Guide to the Human Genome
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Search of human proteins with 4502049

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4502049 aldo-keto reductase family 1, member B1 [Homo
sapiens]
         (316 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]     650   0.0  
gi|223468663 aldo-keto reductase family 1, member B10 [Homo sapi...   475   e-134
gi|122937516 aldo-keto reductase family 1, member B10-like [Homo...   451   e-127
gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo ...   367   e-101
gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]     332   2e-91
gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]    325   3e-89
gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]     325   3e-89
gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]     322   4e-88
gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]    320   8e-88
gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]     320   8e-88
gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]    318   5e-87
gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]    315   4e-86
gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]         119   3e-27
gi|27436962 potassium voltage-gated channel, shaker-related subf...    45   8e-05
gi|27436966 potassium voltage-gated channel, shaker-related subf...    44   2e-04
gi|27436969 potassium voltage-gated channel, shaker-related subf...    44   2e-04
gi|27436964 potassium voltage-gated channel, shaker-related subf...    43   3e-04
gi|4504825 potassium voltage-gated channel, shaker-related subfa...    43   4e-04
gi|56549117 dynamin 1 isoform 2 [Homo sapiens]                         32   0.96 
gi|59853099 dynamin 1 isoform 1 [Homo sapiens]                         32   0.96 
gi|149944410 hypothetical protein LOC57587 [Homo sapiens]              32   0.96 
gi|27436971 potassium voltage-gated channel, shaker-related subf...    31   1.6  
gi|219842266 usherin isoform B [Homo sapiens]                          30   2.1  
gi|4504011 glutamate-cysteine ligase regulatory protein [Homo sa...    30   2.8  
gi|156938336 class II transactivator [Homo sapiens]                    29   4.8  

>gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens]
          Length = 316

 Score =  650 bits (1677), Expect = 0.0
 Identities = 316/316 (100%), Positives = 316/316 (100%)

Query: 1   MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
           MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ
Sbjct: 1   MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60

Query: 61  EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
           EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK
Sbjct: 61  EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120

Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
           EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP
Sbjct: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180

Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
           AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK
Sbjct: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240

Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300
           HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA
Sbjct: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300

Query: 301 LLSCTSHKDYPFHEEF 316
           LLSCTSHKDYPFHEEF
Sbjct: 301 LLSCTSHKDYPFHEEF 316


>gi|223468663 aldo-keto reductase family 1, member B10 [Homo
           sapiens]
          Length = 316

 Score =  475 bits (1222), Expect = e-134
 Identities = 223/316 (70%), Positives = 263/316 (83%)

Query: 1   MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
           MA+ + L+  AKMPI+GLGTWKSP G+V EAVKVAID GYRHIDCA+VYQNE+EVG AIQ
Sbjct: 1   MATFVELSTKAKMPIVGLGTWKSPLGKVKEAVKVAIDAGYRHIDCAYVYQNEHEVGEAIQ 60

Query: 61  EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
           EK++E+ VKRE+LFIVSKLW T+ E+ LV+ A +KTL DLKL YLD+YLIHWP GFK G 
Sbjct: 61  EKIQEKAVKREDLFIVSKLWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKSGD 120

Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
           + FP D+ GN +      LD W AMEELVDEGLVKA+G+SNF+H Q+E +LNKPGLKYKP
Sbjct: 121 DLFPKDDKGNAIGGKATFLDAWEAMEELVDEGLVKALGVSNFSHFQIEKLLNKPGLKYKP 180

Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
             NQ+ECHPYLTQEKLIQYC SKGI VTAYSPLGSPDRPWAKPEDPSLLEDP+IK IAAK
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240

Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300
           H KT AQVLIRF +QRN++VIPKSVTP RI EN +VFDF+LS ++M T+LS+NRNWR C 
Sbjct: 241 HKKTAAQVLIRFHIQRNVIVIPKSVTPARIVENIQVFDFKLSDEEMATILSFNRNWRACN 300

Query: 301 LLSCTSHKDYPFHEEF 316
           +L  +  +DYPF+ E+
Sbjct: 301 VLQSSHLEDYPFNAEY 316


>gi|122937516 aldo-keto reductase family 1, member B10-like [Homo
           sapiens]
          Length = 316

 Score =  451 bits (1161), Expect = e-127
 Identities = 213/316 (67%), Positives = 256/316 (81%)

Query: 1   MASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
           MA+ + L+  AKMPI+GLGTW+S  G+V EAVKVAID  YRHIDCA+ Y+N++EVG AIQ
Sbjct: 1   MATFVELSTKAKMPIVGLGTWRSLLGKVKEAVKVAIDAEYRHIDCAYFYENQHEVGEAIQ 60

Query: 61  EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
           EK++E+ V RE+LFIVSK+W T+ E+ LV+ A +KTL DLKL YLD+YLIHWP GFK G 
Sbjct: 61  EKIQEKAVMREDLFIVSKVWPTFFERPLVRKAFEKTLKDLKLSYLDVYLIHWPQGFKTGD 120

Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
           +FFP D+ GN++      LD W AMEELVDEGLVKA+G+SNFNH Q+E +LNKPGLKYKP
Sbjct: 121 DFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLNKPGLKYKP 180

Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
             NQ+ECHPYLTQEKLIQYC SKGI VTAYSPLGSPDRPWAKPEDPSLLEDP+IK IAAK
Sbjct: 181 VTNQVECHPYLTQEKLIQYCHSKGITVTAYSPLGSPDRPWAKPEDPSLLEDPKIKEIAAK 240

Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCA 300
           H KTTAQVLIRF +QRN+ VIPKS+TP  I EN +VFDF+LS ++M T+LS+NRNWR   
Sbjct: 241 HKKTTAQVLIRFHIQRNVTVIPKSMTPAHIVENIQVFDFKLSDEEMATILSFNRNWRAFD 300

Query: 301 LLSCTSHKDYPFHEEF 316
               +  +D+PF  E+
Sbjct: 301 FKEFSHLEDFPFDAEY 316


>gi|93277124 aldo-keto reductase family 1, member C-like 2 [Homo
           sapiens]
          Length = 320

 Score =  367 bits (941), Expect = e-101
 Identities = 180/323 (55%), Positives = 226/323 (69%), Gaps = 25/323 (7%)

Query: 13  MPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKREE 72
           +P +GL +WK+ PG+VTEAVK AID GYRH DCA+ Y NE EVG  I+ K++E  V+RE+
Sbjct: 4   IPAVGLSSWKASPGKVTEAVKEAIDAGYRHFDCAYFYHNEREVGAGIRCKIKEGAVRRED 63

Query: 73  LFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK------------ 120
           LFI +KLWCT H+K LV+ AC+K+L  LKL+YLDLYLIHWP GFKP              
Sbjct: 64  LFIATKLWCTCHKKSLVETACRKSLKALKLNYLDLYLIHWPMGFKPPHPEWIMSCSELSF 123

Query: 121 -------EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNK 173
                  +  PLDES  V+PSDT+ LDTW AME+LV  GLVK IG+SNFNH Q+E +LNK
Sbjct: 124 CLSHPRVQDLPLDESNMVIPSDTDFLDTWEAMEDLVITGLVKNIGVSNFNHEQLERLLNK 183

Query: 174 PGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPR 233
           PGL++KP  NQIECHPYLTQ+ LI +CQS+ + VTAY PLG         E   L+++P 
Sbjct: 184 PGLRFKPLTNQIECHPYLTQKNLISFCQSRDVSVTAYRPLG------GSCEGVDLIDNPV 237

Query: 234 IKAIAAKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYN 293
           IK IA +H K+ AQ+LIRF +QRN++VIP S+TP  I EN +VFDFEL+  DM  +LS N
Sbjct: 238 IKRIAKEHGKSPAQILIRFQIQRNVIVIPGSITPSHIKENIQVFDFELTQHDMDNILSLN 297

Query: 294 RNWRVCALLSCTSHKDYPFHEEF 316
           RN R+       +HKDYPFH E+
Sbjct: 298 RNLRLAMFPITKNHKDYPFHIEY 320


>gi|5174695 aldo-keto reductase family 1, member D1 [Homo sapiens]
          Length = 326

 Score =  332 bits (852), Expect = 2e-91
 Identities = 159/318 (50%), Positives = 221/318 (69%), Gaps = 5/318 (1%)

Query: 4   RLLLNNGAKMPILGLGTWK----SPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAI 59
           R+ L++G  +PI+GLGT+     +P G    +VKVAID GYRHID A++YQNE+EVG AI
Sbjct: 9   RIPLSDGNSIPIIGLGTYSEPKSTPKGACATSVKVAIDTGYRHIDGAYIYQNEHEVGEAI 68

Query: 60  QEKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPG 119
           +EK+ E  V+RE++F   KLW T H   +V+   ++TL  L+LDY+DLY+I  P  FKPG
Sbjct: 69  REKIAEGKVRREDIFYCGKLWATNHVPEMVRPTLERTLRVLQLDYVDLYIIEVPMAFKPG 128

Query: 120 KEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYK 179
            E +P DE+G  +   +N+  TW AME   D GLVK++G+SNFN  Q+E+ILNKPGLK+K
Sbjct: 129 DEIYPRDENGKWLYHKSNLCATWEAMEACKDAGLVKSLGVSNFNRRQLELILNKPGLKHK 188

Query: 180 PAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRP-WAKPEDPSLLEDPRIKAIA 238
           P  NQ+ECHPY TQ KL+++CQ   IV+TAYSPLG+   P W     P LL+D  + ++ 
Sbjct: 189 PVSNQVECHPYFTQPKLLKFCQQHDIVITAYSPLGTSRNPIWVNVSSPPLLKDALLNSLG 248

Query: 239 AKHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRV 298
            ++NKT AQ+++RF +QR +VVIPKS   ERI ENF++FDF L+ ++M  + + N+N R 
Sbjct: 249 KRYNKTAAQIVLRFNIQRGVVVIPKSFNLERIKENFQIFDFSLTEEEMKDIEALNKNVRF 308

Query: 299 CALLSCTSHKDYPFHEEF 316
             LL    H +YPFH+E+
Sbjct: 309 VELLMWRDHPEYPFHDEY 326


>gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]
          Length = 325

 Score =  325 bits (833), Expect = 3e-89
 Identities = 161/325 (49%), Positives = 226/325 (69%), Gaps = 12/325 (3%)

Query: 2   ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61
           AS +LL+ G KMP++GLGTWKS PGQV  AVK A+ VGYRHIDCA +Y NE E+G A++E
Sbjct: 3   ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKE 62

Query: 62  KLRE-QVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
            +   + V REELF+ SKLW T H    V+ A +KTL+DL+L+YLDLYL+HWP  F+ G 
Sbjct: 63  DVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 122

Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
             FP +  G +    T+  +TW A+E LV +GLV+A+G+SNFN  Q++ IL+   ++  P
Sbjct: 123 NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR--P 180

Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
           AV Q+ECHPYL Q +LI +CQ++G+ VTAYSPLGS DR W  P++P LLE+P + A+A K
Sbjct: 181 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK 240

Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR-VC 299
           + ++ AQ+L+R+ +QR ++ IPKS+TP RI +N KVFDF  S ++M  L + N+NWR + 
Sbjct: 241 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV 300

Query: 300 ALLSC--------TSHKDYPFHEEF 316
            +L+           H  YPF++ +
Sbjct: 301 PMLTVDGKRVPRDAGHPLYPFNDPY 325


>gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]
          Length = 325

 Score =  325 bits (833), Expect = 3e-89
 Identities = 161/325 (49%), Positives = 226/325 (69%), Gaps = 12/325 (3%)

Query: 2   ASRLLLNNGAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQE 61
           AS +LL+ G KMP++GLGTWKS PGQV  AVK A+ VGYRHIDCA +Y NE E+G A++E
Sbjct: 3   ASCVLLHTGQKMPLIGLGTWKSEPGQVKAAVKYALSVGYRHIDCAAIYGNEPEIGEALKE 62

Query: 62  KLRE-QVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
            +   + V REELF+ SKLW T H    V+ A +KTL+DL+L+YLDLYL+HWP  F+ G 
Sbjct: 63  DVGPGKAVPREELFVTSKLWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGD 122

Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
             FP +  G +    T+  +TW A+E LV +GLV+A+G+SNFN  Q++ IL+   ++  P
Sbjct: 123 NPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILSVASVR--P 180

Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAK 240
           AV Q+ECHPYL Q +LI +CQ++G+ VTAYSPLGS DR W  P++P LLE+P + A+A K
Sbjct: 181 AVLQVECHPYLAQNELIAHCQARGLEVTAYSPLGSSDRAWRDPDEPVLLEEPVVLALAEK 240

Query: 241 HNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWR-VC 299
           + ++ AQ+L+R+ +QR ++ IPKS+TP RI +N KVFDF  S ++M  L + N+NWR + 
Sbjct: 241 YGRSPAQILLRWQVQRKVICIPKSITPSRILQNIKVFDFTFSPEEMKQLNALNKNWRYIV 300

Query: 300 ALLSC--------TSHKDYPFHEEF 316
            +L+           H  YPF++ +
Sbjct: 301 PMLTVDGKRVPRDAGHPLYPFNDPY 325


>gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]
          Length = 323

 Score =  322 bits (824), Expect = 4e-88
 Identities = 153/314 (48%), Positives = 215/314 (68%), Gaps = 4/314 (1%)

Query: 7   LNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63
           LN+G  MP+LG GT+   + P  +  EA K+AI+ G+RHID AH+Y NE +VG+AI+ K+
Sbjct: 10  LNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69

Query: 64  REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123
            +  VKRE++F  SKLWC  H   LV+ A +++L +L+LDY+DLYLIH+P   KPG+E  
Sbjct: 70  ADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI 129

Query: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVN 183
           P DE+G ++    ++  TW A+E+  D GL K+IG+SNFN  Q+EMILNKPGLKYKP  N
Sbjct: 130 PKDENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCN 189

Query: 184 QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHN 242
           Q+ECHPY  Q KL+ +C+SK IV+ AYS LGS  + PW  P  P LLEDP + A+A KH 
Sbjct: 190 QVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHK 249

Query: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302
           +T A + +R+ +QR +VV+ KS   +RI +N +VF+F+L+S++M  +   NRN R   L 
Sbjct: 250 RTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLD 309

Query: 303 SCTSHKDYPFHEEF 316
                 +YPF +E+
Sbjct: 310 IFAGPPNYPFSDEY 323


>gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score =  320 bits (821), Expect = 8e-88
 Identities = 154/314 (49%), Positives = 214/314 (68%), Gaps = 4/314 (1%)

Query: 7   LNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63
           LN+G  MP+LG GT+   + P  +  EAVK+AI+ G+ HID AHVY NE +VG+AI+ K+
Sbjct: 10  LNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKI 69

Query: 64  REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123
            +  VKRE++F  SKLW   H   LV+ A +++L +L+LDY+DLYLIH+P   KPG+E  
Sbjct: 70  ADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI 129

Query: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVN 183
           P DE+G ++    ++  TW AME+  D GL K+IG+SNFNH  +EMILNKPGLKYKP  N
Sbjct: 130 PKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCN 189

Query: 184 QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHN 242
           Q+ECHPY  Q KL+ +C+SK IV+ AYS LGS  + PW  P  P LLEDP + A+A KH 
Sbjct: 190 QVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHK 249

Query: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302
           +T A + +R+ +QR +VV+ KS   +RI +N +VF+F+L+S++M  +   NRN R   L 
Sbjct: 250 RTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLD 309

Query: 303 SCTSHKDYPFHEEF 316
                 +YPF +E+
Sbjct: 310 IFAGPPNYPFSDEY 323


>gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]
          Length = 323

 Score =  320 bits (821), Expect = 8e-88
 Identities = 154/314 (49%), Positives = 214/314 (68%), Gaps = 4/314 (1%)

Query: 7   LNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63
           LN+G  MP+LG GT+   + P  +  EAVK+AI+ G+ HID AHVY NE +VG+AI+ K+
Sbjct: 10  LNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKI 69

Query: 64  REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123
            +  VKRE++F  SKLW   H   LV+ A +++L +L+LDY+DLYLIH+P   KPG+E  
Sbjct: 70  ADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI 129

Query: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVN 183
           P DE+G ++    ++  TW AME+  D GL K+IG+SNFNH  +EMILNKPGLKYKP  N
Sbjct: 130 PKDENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPGLKYKPVCN 189

Query: 184 QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGS-PDRPWAKPEDPSLLEDPRIKAIAAKHN 242
           Q+ECHPY  Q KL+ +C+SK IV+ AYS LGS  + PW  P  P LLEDP + A+A KH 
Sbjct: 190 QVECHPYFNQRKLLDFCKSKDIVLVAYSALGSHREEPWVDPNSPVLLEDPVLCALAKKHK 249

Query: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302
           +T A + +R+ +QR +VV+ KS   +RI +N +VF+F+L+S++M  +   NRN R   L 
Sbjct: 250 RTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLD 309

Query: 303 SCTSHKDYPFHEEF 316
                 +YPF +E+
Sbjct: 310 IFAGPPNYPFSDEY 323


>gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]
          Length = 323

 Score =  318 bits (814), Expect = 5e-87
 Identities = 152/317 (47%), Positives = 215/317 (67%), Gaps = 4/317 (1%)

Query: 4   RLLLNNGAKMPILGLGTWKSPP---GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQ 60
           R+ LN+G  MP+LG GT+  P     +  E  K+AI+ G+RHID A++Y NE +VG+AI+
Sbjct: 7   RVELNDGHFMPVLGFGTYAPPEVPRNRAVEVTKLAIEAGFRHIDSAYLYNNEEQVGLAIR 66

Query: 61  EKLREQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGK 120
            K+ +  VKRE++F  SKLWCT+ +  +V+ A + +L  L+LDY+DLYL+H+P   KPG+
Sbjct: 67  SKIADGSVKREDIFYTSKLWCTFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE 126

Query: 121 EFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKP 180
              P DE+G V+    ++  TW  ME+  D GL K+IG+SNFN  Q+EMILNKPGLKYKP
Sbjct: 127 TPLPKDENGKVIFDTVDLSATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNKPGLKYKP 186

Query: 181 AVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP-DRPWAKPEDPSLLEDPRIKAIAA 239
             NQ+ECHPYL Q KL+ +C+SK IV+ A+S LG+   + W  P  P LLEDP + A+A 
Sbjct: 187 VCNQVECHPYLNQSKLLDFCKSKDIVLVAHSALGTQRHKLWVDPNSPVLLEDPVLCALAK 246

Query: 240 KHNKTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVC 299
           KH +T A + +R+ +QR +VV+ KS   +RI EN +VF+F+L+S+DM  L   NRN+R  
Sbjct: 247 KHKQTPALIALRYQLQRGVVVLAKSYNEQRIRENIQVFEFQLTSEDMKVLDGLNRNYRYV 306

Query: 300 ALLSCTSHKDYPFHEEF 316
            +     H DYPF +E+
Sbjct: 307 VMDFLMDHPDYPFSDEY 323


>gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]
          Length = 323

 Score =  315 bits (806), Expect = 4e-86
 Identities = 151/314 (48%), Positives = 211/314 (67%), Gaps = 4/314 (1%)

Query: 7   LNNGAKMPILGLGTWKSPP---GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63
           LN+G  MP+LG GT+  P     +  E  K+AI+ G+RHID AH+Y NE +VG+AI+ K+
Sbjct: 10  LNDGHFMPVLGFGTYAPPEVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQVGLAIRSKI 69

Query: 64  REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFF 123
            +  VKRE++F  SKLW T+H   LV+ A + +L   +LDY+DLYLIH P   KPG+E  
Sbjct: 70  ADGSVKREDIFYTSKLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEELS 129

Query: 124 PLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVN 183
           P DE+G V+    ++  TW AME+  D GL K+IG+SNFN  Q+EMILNKPGLKYKP  N
Sbjct: 130 PTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCN 189

Query: 184 QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSP-DRPWAKPEDPSLLEDPRIKAIAAKHN 242
           Q+ECHPY  + KL+ +C+SK IV+ AYS LGS  D+ W  P  P LLEDP + A+A KH 
Sbjct: 190 QVECHPYFNRSKLLDFCKSKDIVLVAYSALGSQRDKRWVDPNSPVLLEDPVLCALAKKHK 249

Query: 243 KTTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRNWRVCALL 302
           +T A + +R+ +QR +VV+ KS   +RI +N +VF+F+L+++DM  +   +RN       
Sbjct: 250 RTPALIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTAEDMKAIDGLDRNLHYFNSD 309

Query: 303 SCTSHKDYPFHEEF 316
           S  SH +YP+ +E+
Sbjct: 310 SFASHPNYPYSDEY 323


>gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]
          Length = 139

 Score =  119 bits (299), Expect = 3e-27
 Identities = 57/114 (50%), Positives = 80/114 (70%), Gaps = 3/114 (2%)

Query: 7   LNNGAKMPILGLGTW---KSPPGQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKL 63
           LN+G  MP+LG GT+   + P  +  EAVK+AI+ G+ HID AHVY NE +VG+AI+ K+
Sbjct: 10  LNDGHFMPVLGFGTYAPAEVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQVGLAIRSKI 69

Query: 64  REQVVKREELFIVSKLWCTYHEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFK 117
            +  VKRE++F  SKLW   H   LV+ A +++L +L+LDY+DLYLIH+P   K
Sbjct: 70  ADGSVKREDIFYTSKLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVK 123


>gi|27436962 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 2 [Homo sapiens]
          Length = 408

 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 53/234 (22%), Positives = 100/234 (42%), Gaps = 45/234 (19%)

Query: 1   MASRLLLNNGAKMPILGLGTWKSPPGQVTEAV-----KVAIDVGYRHIDCAHVYQNENEV 55
           MA R L  +G ++  LGLGTW +  GQ+++ V      +A + G    D A VY    + 
Sbjct: 78  MAYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYA-AGKA 136

Query: 56  GVAIQEKLREQVVKREELFIVSKLWC---TYHEKGL--------VKGACQKTLSDLKLDY 104
            V +   ++++  +R  L I +KL+       E+GL        +KG+ Q+    L+L+Y
Sbjct: 137 EVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQR----LQLEY 192

Query: 105 LDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNH 164
           +D+   + P    P +E                      AM  ++++G+    G S ++ 
Sbjct: 193 VDVVFANRPDSNTPMEEIV-------------------RAMTHVINQGMAMYWGTSRWSA 233

Query: 165 LQV--EMILNKPGLKYKPAVNQIECHPYLTQE---KLIQYCQSKGIVVTAYSPL 213
           +++     + +      P   Q E H +  ++   +L +     G+    +SPL
Sbjct: 234 MEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPL 287


>gi|27436966 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 1 [Homo sapiens]
          Length = 419

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 52/234 (22%), Positives = 99/234 (42%), Gaps = 45/234 (19%)

Query: 1   MASRLLLNNGAKMPILGLGTWKSPPGQVTEAV-----KVAIDVGYRHIDCAHVYQNENEV 55
           M  R L  +G ++  LGLGTW +  GQ+++ V      +A + G    D A VY    + 
Sbjct: 89  MPHRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYA-AGKA 147

Query: 56  GVAIQEKLREQVVKREELFIVSKLWC---TYHEKGL--------VKGACQKTLSDLKLDY 104
            V +   ++++  +R  L I +KL+       E+GL        +KG+ Q+    L+L+Y
Sbjct: 148 EVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQR----LQLEY 203

Query: 105 LDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNH 164
           +D+   + P    P +E                      AM  ++++G+    G S ++ 
Sbjct: 204 VDVVFANRPDSNTPMEEIV-------------------RAMTHVINQGMAMYWGTSRWSA 244

Query: 165 LQV--EMILNKPGLKYKPAVNQIECHPYLTQE---KLIQYCQSKGIVVTAYSPL 213
           +++     + +      P   Q E H +  ++   +L +     G+    +SPL
Sbjct: 245 MEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPL 298


>gi|27436969 potassium voltage-gated channel, shaker-related
           subfamily, beta member 2 isoform 2 [Homo sapiens]
          Length = 353

 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 42/179 (23%), Positives = 80/179 (44%), Gaps = 32/179 (17%)

Query: 1   MASRLLLNNGAKMPILGLGTWKSPPGQVT-----EAVKVAIDVGYRHIDCAHVYQNENEV 55
           M  R L  +G ++  LGLGTW +  GQ+T     + + +A D G    D A VY    + 
Sbjct: 23  MIYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYA-AGKA 81

Query: 56  GVAIQEKLREQVVKREELFIVSKLWC---TYHEKGL----VKGACQKTLSDLKLDYLDLY 108
            V +   ++++  +R  L I +K++       E+GL    +    + +L  L+L+Y+D+ 
Sbjct: 82  EVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVV 141

Query: 109 LIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
             + P    P +E                   T  AM  ++++G+    G S ++ +++
Sbjct: 142 FANRPDPNTPMEE-------------------TVRAMTHVINQGMAMYWGTSRWSSMEI 181


>gi|27436964 potassium voltage-gated channel, shaker-related
           subfamily, beta member 1 isoform 3 [Homo sapiens]
          Length = 401

 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 52/234 (22%), Positives = 99/234 (42%), Gaps = 45/234 (19%)

Query: 1   MASRLLLNNGAKMPILGLGTWKSPPGQVTEAV-----KVAIDVGYRHIDCAHVYQNENEV 55
           M  R L  +G ++  LGLGTW +  GQ+++ V      +A + G    D A VY    + 
Sbjct: 71  MKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYA-AGKA 129

Query: 56  GVAIQEKLREQVVKREELFIVSKLWC---TYHEKGL--------VKGACQKTLSDLKLDY 104
            V +   ++++  +R  L I +KL+       E+GL        +KG+ Q+    L+L+Y
Sbjct: 130 EVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQR----LQLEY 185

Query: 105 LDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNH 164
           +D+   + P    P +E                      AM  ++++G+    G S ++ 
Sbjct: 186 VDVVFANRPDSNTPMEEIV-------------------RAMTHVINQGMAMYWGTSRWSA 226

Query: 165 LQV--EMILNKPGLKYKPAVNQIECHPYLTQE---KLIQYCQSKGIVVTAYSPL 213
           +++     + +      P   Q E H +  ++   +L +     G+    +SPL
Sbjct: 227 MEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPL 280


>gi|4504825 potassium voltage-gated channel, shaker-related
           subfamily, beta member 2 isoform 1 [Homo sapiens]
          Length = 367

 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 41/176 (23%), Positives = 79/176 (44%), Gaps = 32/176 (18%)

Query: 4   RLLLNNGAKMPILGLGTWKSPPGQVT-----EAVKVAIDVGYRHIDCAHVYQNENEVGVA 58
           R L  +G ++  LGLGTW +  GQ+T     + + +A D G    D A VY    +  V 
Sbjct: 40  RNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYA-AGKAEVV 98

Query: 59  IQEKLREQVVKREELFIVSKLWC---TYHEKGL----VKGACQKTLSDLKLDYLDLYLIH 111
           +   ++++  +R  L I +K++       E+GL    +    + +L  L+L+Y+D+   +
Sbjct: 99  LGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFAN 158

Query: 112 WPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQV 167
            P    P +E                   T  AM  ++++G+    G S ++ +++
Sbjct: 159 RPDPNTPMEE-------------------TVRAMTHVINQGMAMYWGTSRWSSMEI 195


>gi|56549117 dynamin 1 isoform 2 [Homo sapiens]
          Length = 851

 Score = 31.6 bits (70), Expect = 0.96
 Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 10/89 (11%)

Query: 26  GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKR------EELFIVSKL 79
           G+  E V + ID+   +++  H    E+ +G A  ++   Q+ K+      +E+ ++ K 
Sbjct: 469 GRTKEQVMLLIDIELAYMNTNH----EDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKG 524

Query: 80  WCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
           W T +  G++KG  ++    L  + L  Y
Sbjct: 525 WLTINNIGIMKGGSKEYWFVLTAENLSWY 553


>gi|59853099 dynamin 1 isoform 1 [Homo sapiens]
          Length = 864

 Score = 31.6 bits (70), Expect = 0.96
 Identities = 21/89 (23%), Positives = 43/89 (48%), Gaps = 10/89 (11%)

Query: 26  GQVTEAVKVAIDVGYRHIDCAHVYQNENEVGVAIQEKLREQVVKR------EELFIVSKL 79
           G+  E V + ID+   +++  H    E+ +G A  ++   Q+ K+      +E+ ++ K 
Sbjct: 469 GRTKEQVMLLIDIELAYMNTNH----EDFIGFANAQQRSNQMNKKKTSGNQDEILVIRKG 524

Query: 80  WCTYHEKGLVKGACQKTLSDLKLDYLDLY 108
           W T +  G++KG  ++    L  + L  Y
Sbjct: 525 WLTINNIGIMKGGSKEYWFVLTAENLSWY 553


>gi|149944410 hypothetical protein LOC57587 [Homo sapiens]
          Length = 532

 Score = 31.6 bits (70), Expect = 0.96
 Identities = 19/65 (29%), Positives = 27/65 (41%)

Query: 171 LNKPGLKYKPAVNQIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLE 230
           L  P  KYK  +   E  P  T  K   Y +     VT  SPL +PD    +  +  +  
Sbjct: 216 LLSPKHKYKSGIKSTETQPSSTTPKCGHYPEESEDTVTDVSPLSTPDISPLQSFELGIAN 275

Query: 231 DPRIK 235
           D ++K
Sbjct: 276 DQKVK 280


>gi|27436971 potassium voltage-gated channel, shaker-related
           subfamily, beta member 3 [Homo sapiens]
          Length = 404

 Score = 30.8 bits (68), Expect = 1.6
 Identities = 31/119 (26%), Positives = 54/119 (45%), Gaps = 13/119 (10%)

Query: 1   MASRLLLNNGAKMPILGLGTWKSPPGQVT-EAVKVAIDVGYRH----IDCAHVYQNENEV 55
           M  R L  +G ++  LGLGTW +   Q++ E  +  + V Y H     D A VY    + 
Sbjct: 78  MKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAEDVLTVAYEHGVNLFDTAEVYA-AGKA 136

Query: 56  GVAIQEKLREQVVKREELFIVSKLWC---TYHEKGL----VKGACQKTLSDLKLDYLDL 107
              +   L+ +  +R    I +K++       E+GL    +    + +L  L+L Y+D+
Sbjct: 137 ERTLGNILKSKGWRRSSYVITTKIFWGGQAETERGLSRKHIIEGLRGSLERLQLGYVDI 195


>gi|219842266 usherin isoform B [Homo sapiens]
          Length = 5202

 Score = 30.4 bits (67), Expect = 2.1
 Identities = 40/172 (23%), Positives = 71/172 (41%), Gaps = 26/172 (15%)

Query: 126  DESGNVVPSDTNILDTWAAMEELVDEGLVKAIG-ISNFN-HLQVEMILNKPGLKYKPAVN 183
            D+ G VVP    +LD  + M  +  +   K+ G I+++N +L   + L  PG      V 
Sbjct: 2531 DKPGPVVPPI--LLDVKSRMMLVTWQHPRKSNGVITHYNIYLHGRLYLRTPGNVTNCTVM 2588

Query: 184  QIECHPYLTQEKLIQYCQSKGIVVTAYSPLGSPDRPWAKPEDPSLLEDPRIKAIAAKHNK 243
             +  HPY   +  ++ C SKG  ++  S        W  P  P  +  P +       + 
Sbjct: 2589 HL--HPYTAYKFQVEACTSKGCSLSPES-----QTVWTLPGAPEGIPSPEL------FSD 2635

Query: 244  TTAQVLIRFPMQRNLVVIPKSVTPERIAENFKVFDFELSSQDMTTLLSYNRN 295
            T   V+I +    +         P  + ENF +       +++TTL++  R+
Sbjct: 2636 TPTSVIISWQPPTH---------PNGLVENFTIERRVKGKEEVTTLVTLPRS 2678


>gi|4504011 glutamate-cysteine ligase regulatory protein [Homo
           sapiens]
          Length = 274

 Score = 30.0 bits (66), Expect = 2.8
 Identities = 29/118 (24%), Positives = 52/118 (44%), Gaps = 15/118 (12%)

Query: 69  KREELFIVSKLWCTY-HEKGLVKGACQKTLSDLKLDYLDLYLIHWPTGFKPGKEFFPLDE 127
           +REE+ + +KL+    +     + A     S L +  LD  +I  P          P+++
Sbjct: 85  EREEMKVSAKLFIVESNSSSSTRSAVDMACSVLGVAQLDSVIIASP----------PIED 134

Query: 128 SGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNHLQVEMILNKPGLKYKPAVNQI 185
             N+  S  ++   W  +E LV    + AIG S+ +  Q+E +      + KP  NQ+
Sbjct: 135 GVNL--SLEHLQPYWEELENLVQSKKIVAIGTSDLDKTQLEQLYQ--WAQVKPNSNQV 188


>gi|156938336 class II transactivator [Homo sapiens]
          Length = 1130

 Score = 29.3 bits (64), Expect = 4.8
 Identities = 13/33 (39%), Positives = 19/33 (57%)

Query: 10  GAKMPILGLGTWKSPPGQVTEAVKVAIDVGYRH 42
           G  + +LG     SPPG + E  K+A ++G RH
Sbjct: 639 GLYVGLLGRAALDSPPGALAELAKLAWELGRRH 671


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.136    0.416 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,708,857
Number of Sequences: 37866
Number of extensions: 554623
Number of successful extensions: 1269
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1234
Number of HSP's gapped (non-prelim): 25
length of query: 316
length of database: 18,247,518
effective HSP length: 102
effective length of query: 214
effective length of database: 14,385,186
effective search space: 3078429804
effective search space used: 3078429804
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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