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Search of human proteins with 4501969
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|4501969 adrenergic, beta-2-, receptor, surface [Homo
sapiens]
(413 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] 844 0.0
gi|4557265 beta-1-adrenergic receptor [Homo sapiens] 389 e-108
gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens] 314 8e-86
gi|4503383 dopamine receptor D1 [Homo sapiens] 229 3e-60
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 211 1e-54
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 211 1e-54
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 211 1e-54
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 211 1e-54
gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 207 1e-53
gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 207 1e-53
gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 207 1e-53
gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 207 1e-53
gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 207 1e-53
gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] 207 1e-53
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 206 2e-53
gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] 206 4e-53
gi|4503391 dopamine receptor D5 [Homo sapiens] 205 7e-53
gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 205 7e-53
gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 205 7e-53
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 204 9e-53
gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo sap... 189 5e-48
gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo sap... 184 1e-46
gi|4504537 5-hydroxytryptamine (serotonin) receptor 1E [Homo sap... 175 6e-44
gi|110618256 trace amine associated receptor 9 [Homo sapiens] 169 3e-42
gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 167 1e-41
gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 167 1e-41
gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] 167 1e-41
gi|21264324 trace amine associated receptor 1 [Homo sapiens] 167 2e-41
gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo sapi... 162 7e-40
gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo sa... 159 6e-39
>gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens]
Length = 413
Score = 844 bits (2180), Expect = 0.0
Identities = 413/413 (100%), Positives = 413/413 (100%)
Query: 1 MGQPGNGSAFLLAPNRSHAPDHDVTQQRDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK 60
MGQPGNGSAFLLAPNRSHAPDHDVTQQRDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK
Sbjct: 1 MGQPGNGSAFLLAPNRSHAPDHDVTQQRDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAK 60
Query: 61 FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS 120
FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS
Sbjct: 61 FERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTAS 120
Query: 121 IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE 180
IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE
Sbjct: 121 IETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQE 180
Query: 181 AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF 240
AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF
Sbjct: 181 AINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF 240
Query: 241 HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD 300
HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD
Sbjct: 241 HVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQD 300
Query: 301 NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT 360
NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT
Sbjct: 301 NLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIAFQELLCLRRSSLKAYGNGYSSNGNT 360
Query: 361 GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL 413
GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL
Sbjct: 361 GEQSGYHVEQEKENKLLCEDLPGTEDFVGHQGTVPSDNIDSQGRNCSTNDSLL 413
>gi|4557265 beta-1-adrenergic receptor [Homo sapiens]
Length = 477
Score = 389 bits (998), Expect = e-108
Identities = 210/390 (53%), Positives = 259/390 (66%), Gaps = 39/390 (10%)
Query: 4 PGNGSAFLLAPNRSHAPDHDVTQQRDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFER 63
P + A LL P S +P+ ++QQ W GMG++M+LIVL IV GNVLVI AIAK R
Sbjct: 35 PASPPASLLPP-ASESPE-PLSQQ----WTAGMGLLMALIVLLIVAGNVLVIVAIAKTPR 88
Query: 64 LQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIET 123
LQT+TN FI SLA ADLVMGL VVPFGA ++ W +G+F+CE WTS+DVLCVTASIET
Sbjct: 89 LQTLTNLFIMSLASADLVMGLLVVPFGATIVVWGRWEYGSFFCELWTSVDVLCVTASIET 148
Query: 124 LCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAIN 183
LCVIA+DRY AITSPF+YQSLLT+ +AR ++ VW +S L SFLPI MHW+RA EA
Sbjct: 149 LCVIALDRYLAITSPFRYQSLLTRARARGLVCTVWAISALVSFLPILMHWWRAESDEARR 208
Query: 184 CYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRF--- 240
CY + CCDF TN+AYAIASS+VSFYVPL IM FVY RVF+EA++Q++KID E RF
Sbjct: 209 CYNDPKCCDFVTNRAYAIASSVVSFYVPLCIMAFVYLRVFREAQKQVKKIDSCERRFLGG 268
Query: 241 ------------------------HVQNLSQVEQDGRTGHGLRRSSKF-CLKEHKALKTL 275
+ +GR G RR S+ L+E KALKTL
Sbjct: 269 PARPPSPSPSPVPAPAPPPGPPRPAAAAATAPLANGRAGK--RRPSRLVALREQKALKTL 326
Query: 276 GIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCRSPDFRIA 335
GIIMG FTLCWLPFF+ N+V L+ +++ NW+GY NS FNP+IYCRSPDFR A
Sbjct: 327 GIIMGVFTLCWLPFFLANVVKAFHRELVPDRLFVFFNWLGYANSAFNPIIYCRSPDFRKA 386
Query: 336 FQELLCLRRSSLKAYGNGYSSNGNTGEQSG 365
FQ LLC R +A ++++G+ SG
Sbjct: 387 FQGLLCCAR---RAARRRHATHGDRPRASG 413
>gi|4557267 adrenergic, beta-3-, receptor [Homo sapiens]
Length = 408
Score = 314 bits (805), Expect = 8e-86
Identities = 163/321 (50%), Positives = 208/321 (64%), Gaps = 16/321 (4%)
Query: 37 GIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILM 96
G +++L VLA V GN+LVI AIA RLQT+TN F+TSLA ADLVMGL VVP A L
Sbjct: 41 GALLALAVLATVGGNLLVIVAIAWTPRLQTMTNVFVTSLAAADLVMGLLVVPPAATLALT 100
Query: 97 KMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILM 156
W G CE WTS+DVLCVTASIETLC +AVDRY A+T+P +Y +L+TK AR +++
Sbjct: 101 GHWPLGATGCELWTSVDVLCVTASIETLCALAVDRYLAVTNPLRYGALVTKRCARTAVVL 160
Query: 157 VWIVSGLTSFLPIQMHWYR-ATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIM 215
VW+VS SF PI W+R EA C++N CC F +N Y + SS VSFY+PL++M
Sbjct: 161 VWVVSAAVSFAPIMSQWWRVGADAEAQRCHSNPRCCAFASNMPYVLLSSSVSFYLPLLVM 220
Query: 216 VFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQ--------------DGRTGHGLRRS 261
+FVY+RVF A RQL+ + GRF + +G G R +
Sbjct: 221 LFVYARVFVVATRQLRLLRGELGRFPPEESPPAPSRSLAPAPVGTCAPPEGVPACGRRPA 280
Query: 262 SKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVI-QDNLIRKEVYILLNWIGYVNSG 320
L+EH+AL TLG+IMGTFTLCWLPFF+ N++ + +L+ ++ LNW+GY NS
Sbjct: 281 RLLPLREHRALCTLGLIMGTFTLCWLPFFLANVLRALGGPSLVPGPAFLALNWLGYANSA 340
Query: 321 FNPLIYCRSPDFRIAFQELLC 341
FNPLIYCRSPDFR AF+ LLC
Sbjct: 341 FNPLIYCRSPDFRSAFRRLLC 361
>gi|4503383 dopamine receptor D1 [Homo sapiens]
Length = 446
Score = 229 bits (585), Expect = 3e-60
Identities = 122/321 (38%), Positives = 191/321 (59%), Gaps = 18/321 (5%)
Query: 40 MSLIVLAIVFGNVLVITAIAKFERLQT-VTNYFITSLACADLVMGLAVVPFGAAHILMKM 98
+SL++L+ + GN LV A+ +F L++ VTN+F+ SLA +DL++ + V+P+ A +
Sbjct: 30 LSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFVISLAVSDLLVAVLVMPWKAVAEIAGF 89
Query: 99 WTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVW 158
W FG+F C W + D++C TASI LCVI+VDRY+AI+SPF+Y+ +T A ++I + W
Sbjct: 90 WPFGSF-CNIWVAFDIMCSTASILNLCVISVDRYWAISSPFRYERKMTPKAAFILISVAW 148
Query: 159 IVSGLTSFLPIQMHWYRATHQEAINCYANETC-----CDFFTNQAYAIASSIVSFYVPLV 213
+S L SF+P+Q+ W++A + A CD ++ YAI+SS++SFY+P+
Sbjct: 149 TLSVLISFIPVQLSWHKAKPTSPSDGNATSLAETIDNCDSSLSRTYAISSSVISFYIPVA 208
Query: 214 IMVFVYSRVFQEAKRQLQKIDKSE-GRFHVQNLSQVEQDGRTGHGLRRSSKFCL---KEH 269
IM+ Y+R+++ A++Q+++I E H +N +G+ + S F + +E
Sbjct: 209 IMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQTTTGNGKPVECSQPESSFKMSFKRET 268
Query: 270 KALKTLGIIMGTFTLCWLPFFIVNIV------HVIQDNLIRKEVYILLNWIGYVNSGFNP 323
K LKTL +IMG F CWLPFFI+N + Q I + + W G+ NS NP
Sbjct: 269 KVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGETQPFCIDSNTFDVFVWFGWANSSLNP 328
Query: 324 LIYCRSPDFRIAFQELL-CLR 343
+IY + DFR AF LL C R
Sbjct: 329 IIYAFNADFRKAFSTLLGCYR 349
>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
Length = 455
Score = 211 bits (537), Expect = 1e-54
Identities = 125/352 (35%), Positives = 196/352 (55%), Gaps = 29/352 (8%)
Query: 36 MGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHIL 95
+G+++ ++L V GN+LVI ++A L +VT+Y+I +LA ADL++ V+PF A +
Sbjct: 29 LGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEV 88
Query: 96 MKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIIL 155
+ W FG +C W ++DVLC TASI LC+I++DRY ++ P +Y +++T+ + + +L
Sbjct: 89 LGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALL 148
Query: 156 MVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIM 215
VW +S + S P+ W + ++ ET C Y + S++ SFY+PL I+
Sbjct: 149 CVWALSLVISIGPL-FGWRQPAPED-------ETICQINEEPGYVLFSALGSFYLPLAII 200
Query: 216 VFVYSRVFQEAKRQLQ------KIDKSEG-----RFHVQNL----SQVEQDGRTGHGLRR 260
+ +Y RV+ AKR+ + K DKS+ R H +N S + H R
Sbjct: 201 LVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVR 260
Query: 261 SSKFCLKEHKALKTLGIIMGTFTLCWLPFFIV-NIVHVIQDNLIRKEVYILLNWIGYVNS 319
KF +E KA KTLGI++G F LCWLPFF+V I D + V+ ++ W+GY+NS
Sbjct: 261 LLKFS-REKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNS 319
Query: 320 GFNPLIY-CRSPDFRIAFQELL---CLRRSSLKAYGNGYSSNGNTGEQSGYH 367
NP+IY C S +F+ AFQ +L CL R + GY+ + + G H
Sbjct: 320 CINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTLHPPSQAVEGQH 371
>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
Length = 466
Score = 211 bits (537), Expect = 1e-54
Identities = 125/352 (35%), Positives = 196/352 (55%), Gaps = 29/352 (8%)
Query: 36 MGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHIL 95
+G+++ ++L V GN+LVI ++A L +VT+Y+I +LA ADL++ V+PF A +
Sbjct: 29 LGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEV 88
Query: 96 MKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIIL 155
+ W FG +C W ++DVLC TASI LC+I++DRY ++ P +Y +++T+ + + +L
Sbjct: 89 LGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALL 148
Query: 156 MVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIM 215
VW +S + S P+ W + ++ ET C Y + S++ SFY+PL I+
Sbjct: 149 CVWALSLVISIGPL-FGWRQPAPED-------ETICQINEEPGYVLFSALGSFYLPLAII 200
Query: 216 VFVYSRVFQEAKRQLQ------KIDKSEG-----RFHVQNL----SQVEQDGRTGHGLRR 260
+ +Y RV+ AKR+ + K DKS+ R H +N S + H R
Sbjct: 201 LVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVR 260
Query: 261 SSKFCLKEHKALKTLGIIMGTFTLCWLPFFIV-NIVHVIQDNLIRKEVYILLNWIGYVNS 319
KF +E KA KTLGI++G F LCWLPFF+V I D + V+ ++ W+GY+NS
Sbjct: 261 LLKFS-REKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNS 319
Query: 320 GFNPLIY-CRSPDFRIAFQELL---CLRRSSLKAYGNGYSSNGNTGEQSGYH 367
NP+IY C S +F+ AFQ +L CL R + GY+ + + G H
Sbjct: 320 CINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTLHPPSQAVEGQH 371
>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
Length = 475
Score = 211 bits (537), Expect = 1e-54
Identities = 125/352 (35%), Positives = 196/352 (55%), Gaps = 29/352 (8%)
Query: 36 MGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHIL 95
+G+++ ++L V GN+LVI ++A L +VT+Y+I +LA ADL++ V+PF A +
Sbjct: 29 LGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEV 88
Query: 96 MKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIIL 155
+ W FG +C W ++DVLC TASI LC+I++DRY ++ P +Y +++T+ + + +L
Sbjct: 89 LGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALL 148
Query: 156 MVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIM 215
VW +S + S P+ W + ++ ET C Y + S++ SFY+PL I+
Sbjct: 149 CVWALSLVISIGPL-FGWRQPAPED-------ETICQINEEPGYVLFSALGSFYLPLAII 200
Query: 216 VFVYSRVFQEAKRQLQ------KIDKSEG-----RFHVQNL----SQVEQDGRTGHGLRR 260
+ +Y RV+ AKR+ + K DKS+ R H +N S + H R
Sbjct: 201 LVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVR 260
Query: 261 SSKFCLKEHKALKTLGIIMGTFTLCWLPFFIV-NIVHVIQDNLIRKEVYILLNWIGYVNS 319
KF +E KA KTLGI++G F LCWLPFF+V I D + V+ ++ W+GY+NS
Sbjct: 261 LLKFS-REKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNS 319
Query: 320 GFNPLIY-CRSPDFRIAFQELL---CLRRSSLKAYGNGYSSNGNTGEQSGYH 367
NP+IY C S +F+ AFQ +L CL R + GY+ + + G H
Sbjct: 320 CINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTLHPPSQAVEGQH 371
>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
Length = 429
Score = 211 bits (537), Expect = 1e-54
Identities = 125/352 (35%), Positives = 196/352 (55%), Gaps = 29/352 (8%)
Query: 36 MGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHIL 95
+G+++ ++L V GN+LVI ++A L +VT+Y+I +LA ADL++ V+PF A +
Sbjct: 29 LGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIVNLAVADLLLTSTVLPFSAIFEV 88
Query: 96 MKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIIL 155
+ W FG +C W ++DVLC TASI LC+I++DRY ++ P +Y +++T+ + + +L
Sbjct: 89 LGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIVTQRRGLMALL 148
Query: 156 MVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIM 215
VW +S + S P+ W + ++ ET C Y + S++ SFY+PL I+
Sbjct: 149 CVWALSLVISIGPL-FGWRQPAPED-------ETICQINEEPGYVLFSALGSFYLPLAII 200
Query: 216 VFVYSRVFQEAKRQLQ------KIDKSEG-----RFHVQNL----SQVEQDGRTGHGLRR 260
+ +Y RV+ AKR+ + K DKS+ R H +N S + H R
Sbjct: 201 LVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASAKTKTHFSVR 260
Query: 261 SSKFCLKEHKALKTLGIIMGTFTLCWLPFFIV-NIVHVIQDNLIRKEVYILLNWIGYVNS 319
KF +E KA KTLGI++G F LCWLPFF+V I D + V+ ++ W+GY+NS
Sbjct: 261 LLKFS-REKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIVFWLGYLNS 319
Query: 320 GFNPLIY-CRSPDFRIAFQELL---CLRRSSLKAYGNGYSSNGNTGEQSGYH 367
NP+IY C S +F+ AFQ +L CL R + GY+ + + G H
Sbjct: 320 CINPIIYPCSSQEFKKAFQNVLRIQCLCRKQSSKHALGYTLHPPSQAVEGQH 371
>gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens]
Length = 359
Score = 207 bits (527), Expect = 1e-53
Identities = 115/310 (37%), Positives = 170/310 (54%), Gaps = 15/310 (4%)
Query: 40 MSLIVLAIVFGNVLVITAIAKFERLQTV-TNYFITSLACADLVMGLAVVPFGAAHILMKM 98
+S ++L + GN+LV+ A+ +L+ + TNYFI SLA ADL++ + V+PFGA ++ +
Sbjct: 26 LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
Query: 99 WTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAI-TSPFKYQSLLTKNKARVIILMV 157
W +G +C TS+DVL TASI LC I++DRY+AI P Y++ +T + +++
Sbjct: 86 WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
Query: 158 WIVSGLTSFLPIQMHWYR-----ATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPL 212
W++ SFLPI W + N +N T C F N+ YAI S+V+FY+P
Sbjct: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205
Query: 213 VIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKAL 272
++MV Y R++ AK +I + D + H +R E KA
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR-------TETKAA 258
Query: 273 KTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYC-RSPD 331
KTL IIMG F LCW PFF+ NIV D + +V+ W+GY+NSG NP +Y +
Sbjct: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKS 318
Query: 332 FRIAFQELLC 341
FR AF +LC
Sbjct: 319 FRRAFLIILC 328
>gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens]
Length = 428
Score = 207 bits (527), Expect = 1e-53
Identities = 115/310 (37%), Positives = 170/310 (54%), Gaps = 15/310 (4%)
Query: 40 MSLIVLAIVFGNVLVITAIAKFERLQTV-TNYFITSLACADLVMGLAVVPFGAAHILMKM 98
+S ++L + GN+LV+ A+ +L+ + TNYFI SLA ADL++ + V+PFGA ++ +
Sbjct: 26 LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
Query: 99 WTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAI-TSPFKYQSLLTKNKARVIILMV 157
W +G +C TS+DVL TASI LC I++DRY+AI P Y++ +T + +++
Sbjct: 86 WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
Query: 158 WIVSGLTSFLPIQMHWYR-----ATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPL 212
W++ SFLPI W + N +N T C F N+ YAI S+V+FY+P
Sbjct: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205
Query: 213 VIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKAL 272
++MV Y R++ AK +I + D + H +R E KA
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR-------TETKAA 258
Query: 273 KTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYC-RSPD 331
KTL IIMG F LCW PFF+ NIV D + +V+ W+GY+NSG NP +Y +
Sbjct: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKS 318
Query: 332 FRIAFQELLC 341
FR AF +LC
Sbjct: 319 FRRAFLIILC 328
>gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens]
Length = 360
Score = 207 bits (527), Expect = 1e-53
Identities = 115/310 (37%), Positives = 170/310 (54%), Gaps = 15/310 (4%)
Query: 40 MSLIVLAIVFGNVLVITAIAKFERLQTV-TNYFITSLACADLVMGLAVVPFGAAHILMKM 98
+S ++L + GN+LV+ A+ +L+ + TNYFI SLA ADL++ + V+PFGA ++ +
Sbjct: 26 LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
Query: 99 WTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAI-TSPFKYQSLLTKNKARVIILMV 157
W +G +C TS+DVL TASI LC I++DRY+AI P Y++ +T + +++
Sbjct: 86 WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
Query: 158 WIVSGLTSFLPIQMHWYR-----ATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPL 212
W++ SFLPI W + N +N T C F N+ YAI S+V+FY+P
Sbjct: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205
Query: 213 VIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKAL 272
++MV Y R++ AK +I + D + H +R E KA
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR-------TETKAA 258
Query: 273 KTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYC-RSPD 331
KTL IIMG F LCW PFF+ NIV D + +V+ W+GY+NSG NP +Y +
Sbjct: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKS 318
Query: 332 FRIAFQELLC 341
FR AF +LC
Sbjct: 319 FRRAFLIILC 328
>gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens]
Length = 387
Score = 207 bits (527), Expect = 1e-53
Identities = 115/310 (37%), Positives = 170/310 (54%), Gaps = 15/310 (4%)
Query: 40 MSLIVLAIVFGNVLVITAIAKFERLQTV-TNYFITSLACADLVMGLAVVPFGAAHILMKM 98
+S ++L + GN+LV+ A+ +L+ + TNYFI SLA ADL++ + V+PFGA ++ +
Sbjct: 26 LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
Query: 99 WTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAI-TSPFKYQSLLTKNKARVIILMV 157
W +G +C TS+DVL TASI LC I++DRY+AI P Y++ +T + +++
Sbjct: 86 WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
Query: 158 WIVSGLTSFLPIQMHWYR-----ATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPL 212
W++ SFLPI W + N +N T C F N+ YAI S+V+FY+P
Sbjct: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205
Query: 213 VIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKAL 272
++MV Y R++ AK +I + D + H +R E KA
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR-------TETKAA 258
Query: 273 KTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYC-RSPD 331
KTL IIMG F LCW PFF+ NIV D + +V+ W+GY+NSG NP +Y +
Sbjct: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKS 318
Query: 332 FRIAFQELLC 341
FR AF +LC
Sbjct: 319 FRRAFLIILC 328
>gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens]
Length = 378
Score = 207 bits (527), Expect = 1e-53
Identities = 115/310 (37%), Positives = 170/310 (54%), Gaps = 15/310 (4%)
Query: 40 MSLIVLAIVFGNVLVITAIAKFERLQTV-TNYFITSLACADLVMGLAVVPFGAAHILMKM 98
+S ++L + GN+LV+ A+ +L+ + TNYFI SLA ADL++ + V+PFGA ++ +
Sbjct: 26 LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
Query: 99 WTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAI-TSPFKYQSLLTKNKARVIILMV 157
W +G +C TS+DVL TASI LC I++DRY+AI P Y++ +T + +++
Sbjct: 86 WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
Query: 158 WIVSGLTSFLPIQMHWYR-----ATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPL 212
W++ SFLPI W + N +N T C F N+ YAI S+V+FY+P
Sbjct: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205
Query: 213 VIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKAL 272
++MV Y R++ AK +I + D + H +R E KA
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR-------TETKAA 258
Query: 273 KTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYC-RSPD 331
KTL IIMG F LCW PFF+ NIV D + +V+ W+GY+NSG NP +Y +
Sbjct: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKS 318
Query: 332 FRIAFQELLC 341
FR AF +LC
Sbjct: 319 FRRAFLIILC 328
>gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens]
Length = 388
Score = 207 bits (527), Expect = 1e-53
Identities = 115/310 (37%), Positives = 170/310 (54%), Gaps = 15/310 (4%)
Query: 40 MSLIVLAIVFGNVLVITAIAKFERLQTV-TNYFITSLACADLVMGLAVVPFGAAHILMKM 98
+S ++L + GN+LV+ A+ +L+ + TNYFI SLA ADL++ + V+PFGA ++ +
Sbjct: 26 LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
Query: 99 WTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAI-TSPFKYQSLLTKNKARVIILMV 157
W +G +C TS+DVL TASI LC I++DRY+AI P Y++ +T + +++
Sbjct: 86 WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
Query: 158 WIVSGLTSFLPIQMHWYR-----ATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPL 212
W++ SFLPI W + N +N T C F N+ YAI S+V+FY+P
Sbjct: 146 WVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPF 205
Query: 213 VIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKAL 272
++MV Y R++ AK +I + D + H +R E KA
Sbjct: 206 LLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRMR-------TETKAA 258
Query: 273 KTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYC-RSPD 331
KTL IIMG F LCW PFF+ NIV D + +V+ W+GY+NSG NP +Y +
Sbjct: 259 KTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYINSGLNPFLYAFLNKS 318
Query: 332 FRIAFQELLC 341
FR AF +LC
Sbjct: 319 FRRAFLIILC 328
>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
Length = 572
Score = 206 bits (525), Expect = 2e-53
Identities = 129/340 (37%), Positives = 187/340 (55%), Gaps = 41/340 (12%)
Query: 34 VGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAH 93
VG+G+ ++ +L V GN+LVI ++A LQTVTNYFI +LA ADL++ V+PF A
Sbjct: 97 VGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATM 156
Query: 94 ILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVI 153
++ W FG +C+ W ++DVLC TASI +LC I+VDRY + KY +++T+ KA I
Sbjct: 157 EVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAI 216
Query: 154 ILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLV 213
+ ++W+V+ + S P+ + W + E C YA+ SS+ SFY+P+
Sbjct: 217 LALLWVVALVVSVGPL-LGWKEPVPPD-------ERFCGITEEAGYAVFSSVCSFYLPMA 268
Query: 214 IMVFVYSRVFQEA-----------KRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLR--- 259
++V +Y RV+ A KR+ K + R H + + DG HG+R
Sbjct: 269 VIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRG-AATGADG--AHGMRSAK 325
Query: 260 ----RSS------KFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKE-VY 308
RSS KF +E KA KTL I++G F LCW PFF V + + L E V+
Sbjct: 326 GHTFRSSLSVRLLKFS-REKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVF 384
Query: 309 ILLNWIGYVNSGFNPLIY-CRSPDFRIAFQELL---CLRR 344
++ W+GY NS NPLIY C S +F+ AF LL C RR
Sbjct: 385 KVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQCRRR 424
>gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens]
Length = 402
Score = 206 bits (523), Expect = 4e-53
Identities = 116/324 (35%), Positives = 172/324 (53%), Gaps = 29/324 (8%)
Query: 40 MSLIVLAIVFGNVLVITAIAKFERLQTV-TNYFITSLACADLVMGLAVVPFGAAHILMKM 98
+S ++L + GN+LV+ A+ +L+ + TNYFI SLA ADL++ + V+PFGA ++ +
Sbjct: 26 LSTVILMAILGNLLVMVAVCWDRQLRKIKTNYFIVSLAFADLLVSVLVMPFGAIELVQDI 85
Query: 99 WTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAI-TSPFKYQSLLTKNKARVIILMV 157
W +G +C TS+DVL TASI LC I++DRY+AI P Y++ +T + +++
Sbjct: 86 WIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYAICCQPLVYRNKMTPLRIALMLGGC 145
Query: 158 WIVSGLTSFLPIQMHW-------------------YRATHQEAINCYANETCCDFFTNQA 198
W++ SFLPI W + A + N +N T C F N+
Sbjct: 146 WVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDFHAIEKRKFNQNSNSTYCVFMVNKP 205
Query: 199 YAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGL 258
YAI S+V+FY+P ++MV Y R++ AK +I + D + H +
Sbjct: 206 YAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQIQMLQRAGASSESRPQSADQHSTHRM 265
Query: 259 RRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVN 318
R E KA KTL IIMG F LCW PFF+ NIV D + +V+ W+GY+N
Sbjct: 266 R-------TETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQVWTAFLWLGYIN 318
Query: 319 SGFNPLIYC-RSPDFRIAFQELLC 341
SG NP +Y + FR AF +LC
Sbjct: 319 SGLNPFLYAFLNKSFRRAFLIILC 342
>gi|4503391 dopamine receptor D5 [Homo sapiens]
Length = 477
Score = 205 bits (521), Expect = 7e-53
Identities = 119/332 (35%), Positives = 183/332 (55%), Gaps = 34/332 (10%)
Query: 39 VMSLIVLAIVFGNVLVITAIAKFERLQT-VTNYFITSLACADLVMGLAVVPFGAAHILMK 97
+++L+++ + GNVLV AI + L+ +TN FI SLA +DL + L V+P+ A +
Sbjct: 46 LLTLLIIWTLLGNVLVCAAIVRSRHLRANMTNVFIVSLAVSDLFVALLVMPWKAVAEVAG 105
Query: 98 MWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMV 157
W FG F C+ W + D++C TASI LCVI+VDRY+AI+ PF+Y+ +T+ A V++ +
Sbjct: 106 YWPFGAF-CDVWVAFDIMCSTASILNLCVISVDRYWAISRPFRYKRKMTQRMALVMVGLA 164
Query: 158 WIVSGLTSFLPIQMHWYRATHQ-----EAINCYANET--------------CCDFFTNQA 198
W +S L SF+P+Q++W+R + N AN T CD N+
Sbjct: 165 WTLSILISFIPVQLNWHRDQAASWGGLDLPNNLANWTPWEEDFWEPDVNAENCDSSLNRT 224
Query: 199 YAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGL 258
YAI+SS++SFY+P+ IM+ Y+R+++ A+ Q+++I E + L
Sbjct: 225 YAISSSLISFYIPVAIMIVTYTRIYRIAQVQIRRISSLERAAEHAQSCRSSAACAPDTSL 284
Query: 259 RRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDN----------LIRKEVY 308
R S K KE K LKTL +IMG F CWLPFFI+N + + + +
Sbjct: 285 RASIK---KETKVLKTLSVIMGVFVCCWLPFFILNCMVPFCSGHPEGPPAGFPCVSETTF 341
Query: 309 ILLNWIGYVNSGFNPLIYCRSPDFRIAFQELL 340
+ W G+ NS NP+IY + DF+ F +LL
Sbjct: 342 DVFVWFGWANSSLNPVIYAFNADFQKVFAQLL 373
>gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens]
Length = 397
Score = 205 bits (521), Expect = 7e-53
Identities = 111/351 (31%), Positives = 188/351 (53%), Gaps = 27/351 (7%)
Query: 38 IVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMK 97
+V+++++L V GNV+V A+ RL+ +TN FI SLA DL++GL V+PF A + L
Sbjct: 23 VVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSC 82
Query: 98 MWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMV 157
W+FG +C +TS+DV+ TASI L +I++DRY A+ P +Y L+T + + ++++
Sbjct: 83 KWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLI 142
Query: 158 WIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVF 217
W++S SFL I + W N ++ C N+ Y + +V+FY+PL+IM
Sbjct: 143 WVISITLSFLSIHLGWNSRNETSKGNHTTSK--CKVQVNEVYGLVDGLVTFYLPLLIMCI 200
Query: 218 VYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGI 277
Y R+F+ A+ Q ++I+ H+ + ++EHKA TL
Sbjct: 201 TYYRIFKVARDQAKRIN------HISSWKAA----------------TIREHKATVTLAA 238
Query: 278 IMGTFTLCWLPFFIVNIVHVIQ-DNLIRKEVYILLNWIGYVNSGFNPLIYCR-SPDFRIA 335
+MG F +CW P+F + ++ D+ I + + ++ W+GY NS NP++Y + DFR
Sbjct: 239 VMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTG 298
Query: 336 FQELLCLRRSSLKAYGNGYSSNGN-TGEQSGYHVEQEKENKLLCEDLPGTE 385
+Q+L C R ++ ++ SN + Q++E L + GTE
Sbjct: 299 YQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTE 349
>gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens]
Length = 359
Score = 205 bits (521), Expect = 7e-53
Identities = 111/351 (31%), Positives = 188/351 (53%), Gaps = 27/351 (7%)
Query: 38 IVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMK 97
+V+++++L V GNV+V A+ RL+ +TN FI SLA DL++GL V+PF A + L
Sbjct: 23 VVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAIYQLSC 82
Query: 98 MWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMV 157
W+FG +C +TS+DV+ TASI L +I++DRY A+ P +Y L+T + + ++++
Sbjct: 83 KWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAISLVLI 142
Query: 158 WIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIMVF 217
W++S SFL I + W N ++ C N+ Y + +V+FY+PL+IM
Sbjct: 143 WVISITLSFLSIHLGWNSRNETSKGNHTTSK--CKVQVNEVYGLVDGLVTFYLPLLIMCI 200
Query: 218 VYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKTLGI 277
Y R+F+ A+ Q ++I+ H+ + ++EHKA TL
Sbjct: 201 TYYRIFKVARDQAKRIN------HISSWKAA----------------TIREHKATVTLAA 238
Query: 278 IMGTFTLCWLPFFIVNIVHVIQ-DNLIRKEVYILLNWIGYVNSGFNPLIYCR-SPDFRIA 335
+MG F +CW P+F + ++ D+ I + + ++ W+GY NS NP++Y + DFR
Sbjct: 239 VMGAFIICWFPYFTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAALNRDFRTG 298
Query: 336 FQELLCLRRSSLKAYGNGYSSNGN-TGEQSGYHVEQEKENKLLCEDLPGTE 385
+Q+L C R ++ ++ SN + Q++E L + GTE
Sbjct: 299 YQQLFCCRLANRNSHKTSLRSNASQLSRTQSREPRQQEEKPLKLQVWSGTE 349
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 204 bits (520), Expect = 9e-53
Identities = 122/355 (34%), Positives = 189/355 (53%), Gaps = 35/355 (9%)
Query: 8 SAFLLAPNRSHAPDHDVTQQRDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTV 67
+A PN++ + + Q D + +G+V+ +L + GN+LVI ++A L+T
Sbjct: 22 NANFTGPNQTSS--NSTLPQLDITRAISVGLVLGAFILFAIVGNILVILSVACNRHLRTP 79
Query: 68 TNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVI 127
TNYFI +LA ADL++ V+PF AA ++ W G +C+ W ++DVLC TASI +LC I
Sbjct: 80 TNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLCCTASILSLCAI 139
Query: 128 AVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYAN 187
++DRY + +Y +L+T+ KA + +L VW++S + S P+ + W + C
Sbjct: 140 SIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPL-LGWKEPAPNDDKECGVT 198
Query: 188 ETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKS----------- 236
E YA+ SS+ SFY+PL +++ +Y RV+ AKR + ++
Sbjct: 199 E-------EPFYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVMKEMSNSKEL 251
Query: 237 -----EGRFHVQNLSQVEQDGRTGHGLRRSSKFCL----KEHKALKTLGIIMGTFTLCWL 287
FH LS + GH R S L +E KA KTLGI++G F LCWL
Sbjct: 252 TLRIHSKNFHEDTLSSTK---AKGHNPRSSIAVKLFKFSREKKAAKTLGIVVGMFILCWL 308
Query: 288 PFFIVNIVHVIQDNLIRKE-VYILLNWIGYVNSGFNPLIY-CRSPDFRIAFQELL 340
PFFI + + L + V+ ++ W+GY NS NP+IY C S +F+ AF +L
Sbjct: 309 PFFIALPLGSLFSTLKPPDAVFKVVFWLGYFNSCLNPIIYPCSSKEFKRAFVRIL 363
>gi|4504535 5-hydroxytryptamine (serotonin) receptor 1D [Homo
sapiens]
Length = 377
Score = 189 bits (479), Expect = 5e-48
Identities = 115/348 (33%), Positives = 179/348 (51%), Gaps = 44/348 (12%)
Query: 34 VGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAH 93
+ + +V+S+I LA V N V+T I +L T NY I SLA DL++ + V+P A+
Sbjct: 39 ISLAVVLSVITLATVLSNAFVLTTILLTRKLHTPANYLIGSLATTDLLVSILVMPISIAY 98
Query: 94 ILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVI 153
+ W FG C+ W S D+ C TASI LCVIA+DRY+AIT +Y T A +
Sbjct: 99 TITHTWNFGQILCDIWLSSDITCCTASILHLCVIALDRYWAITDALEYSKRRTAGHAATM 158
Query: 154 ILMVWIVSGLTSFLPIQMHWYRATHQEAI-NCYANETCCDFFTNQ-AYAIASSIVSFYVP 211
I +VW +S S P + W +A QE + +C N T+Q +Y I S+ +FY+P
Sbjct: 159 IAIVWAISICISIPP--LFWRQAKAQEEMSDCLVN-------TSQISYTIYSTCGAFYIP 209
Query: 212 LVIMVFVYSRVFQEAKRQLQKIDKSEGRFHV----------QNLSQVEQDGRTGH----- 256
V+++ +Y R+++ A+ ++ G+ +L + GH
Sbjct: 210 SVLLIILYGRIYRAARNRILNPPSLYGKRFTTAHLITGSAGSSLCSLNSSLHEGHSHSAG 269
Query: 257 ---------------GLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIV-HVIQD 300
L R +E KA K LGII+G F +CWLPFF+V++V + +D
Sbjct: 270 SPLFFNHVKIKLADSALERKRISAARERKATKILGIILGAFIICWLPFFVVSLVLPICRD 329
Query: 301 NL-IRKEVYILLNWIGYVNSGFNPLIY-CRSPDFRIAFQELLCLRRSS 346
+ I ++ W+GY+NS NP+IY + +FR AFQ+++ R++S
Sbjct: 330 SCWIHPALFDFFTWLGYLNSLINPIIYTVFNEEFRQAFQKIVPFRKAS 377
>gi|4504533 5-hydroxytryptamine (serotonin) receptor 1B [Homo
sapiens]
Length = 390
Score = 184 bits (468), Expect = 1e-46
Identities = 117/386 (30%), Positives = 189/386 (48%), Gaps = 51/386 (13%)
Query: 4 PGNGSAFLLAPNRSHAPDHDVTQQ----RDEV---WVVGMGIVMSLIVLAIVFGNVLVIT 56
P ++ N S AP + + + +D + W V + ++++LI LA N VI
Sbjct: 13 PAGSETWVPQANLSSAPSQNCSAKDYIYQDSISLPWKVLLVMLLALITLATTLSNAFVIA 72
Query: 57 AIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLC 116
+ + +L T NY I SLA DL++ + V+P + + WT G C+FW S D+ C
Sbjct: 73 TVYRTRKLHTPANYLIASLAVTDLLVSILVMPISTMYTVTGRWTLGQVVCDFWLSSDITC 132
Query: 117 VTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRA 176
TASI LCVIA+DRY+AIT +Y + T +A V+I +VW+ S S P W +A
Sbjct: 133 CTASILHLCVIALDRYWAITDAVEYSAKRTPKRAAVMIALVWVFSISISLPP--FFWRQA 190
Query: 177 THQEAIN-CYANETCCDFFTNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQK--- 232
+E ++ C N + Y + S++ +FY P ++++ +Y R++ EA+ ++ K
Sbjct: 191 KAEEEVSECVVNT------DHILYTVYSTVGAFYFPTLLLIALYGRIYVEARSRILKQTP 244
Query: 233 -------------IDKSEGRFHVQNLSQVEQDGRTGHG----------------LRRSSK 263
D V +++ D + G L +
Sbjct: 245 NRTGKRLTRAQLITDSPGSTSSVTSINSRVPDVPSESGSPVYVNQVKVRVSDALLEKKKL 304
Query: 264 FCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNL--IRKEVYILLNWIGYVNSGF 321
+E KA KTLGII+G F +CWLPFFI+++V I + ++ W+GY+NS
Sbjct: 305 MAARERKATKTLGIILGAFIVCWLPFFIISLVMPICKDACWFHLAIFDFFTWLGYLNSLI 364
Query: 322 NPLIYCRS-PDFRIAFQELLCLRRSS 346
NP+IY S DF+ AF +L+ + +S
Sbjct: 365 NPIIYTMSNEDFKQAFHKLIRFKCTS 390
>gi|4504537 5-hydroxytryptamine (serotonin) receptor 1E [Homo
sapiens]
Length = 365
Score = 175 bits (444), Expect = 6e-44
Identities = 113/349 (32%), Positives = 166/349 (47%), Gaps = 50/349 (14%)
Query: 36 MGIVMSLIVLAIVFG--NVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAH 93
M I M+L+V+ + N+ VI AI ++L NY I SLA DL++ + V+P +
Sbjct: 23 MLICMTLVVITTLTTLLNLAVIMAIGTTKKLHQPANYLICSLAVTDLLVAVLVMPLSIIY 82
Query: 94 ILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVI 153
I+M W G F CE W S+D+ C T SI LCVIA+DRY+AIT+ +Y T +A ++
Sbjct: 83 IVMDRWKLGYFLCEVWLSVDMTCCTCSILHLCVIALDRYWAITNAIEYARKRTAKRAALM 142
Query: 154 ILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLV 213
IL VW +S S P+ +R C + Y I S++ +FY+PL
Sbjct: 143 ILTVWTISIFISMPPLFWRSHRRLSPPPSQCTIQH------DHVIYTIYSTLGAFYIPLT 196
Query: 214 IMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQ----------------------- 250
+++ +Y R++ AK QK S H+ N S Q
Sbjct: 197 LILILYYRIYHAAKSLYQKRGSSR---HLSNRSTDSQNSFASCKLTQTFCVSDFSTSDPT 253
Query: 251 ---------------DGRTGHGLRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIV 295
D H R +E KA + LG+I+G F L WLPFFI ++
Sbjct: 254 TEFEKFHASIRIPPFDNDLDHPGERQQISSTRERKAARILGLILGAFILSWLPFFIKELI 313
Query: 296 HVIQDNLIRKEVYILLNWIGYVNSGFNPLIYCR-SPDFRIAFQELLCLR 343
+ + EV L W+GYVNS NPL+Y + DF++AF++L+ R
Sbjct: 314 VGLSIYTVSSEVADFLTWLGYVNSLINPLLYTSFNEDFKLAFKKLIRCR 362
>gi|110618256 trace amine associated receptor 9 [Homo sapiens]
Length = 348
Score = 169 bits (429), Expect = 3e-42
Identities = 102/298 (34%), Positives = 155/298 (52%), Gaps = 28/298 (9%)
Query: 33 VVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAA 92
V+G G V++ FGN+LV+ AI F++L T TN+ I SLACAD ++G+ V+PF
Sbjct: 38 VLGFGAVLA------AFGNLLVMIAILHFKQLHTPTNFLIASLACADFLVGVTVMPFSTV 91
Query: 93 HILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARV 152
+ W FG+ +C+F T D AS+ LC I+VDRY A+T P Y + T + + +
Sbjct: 92 RSVESCWYFGDSYCKFHTCFDTSFCFASLFHLCCISVDRYIAVTDPLTYPTKFTVSVSGI 151
Query: 153 IILMVWIVSGLTSFLPIQMHWYRATHQEAI-NCYANETC---CDFFTNQAYAIASSIVSF 208
I++ W S SF +Y ++E I TC C NQ + + ++ F
Sbjct: 152 CIVLSWFFSVTYSF----SIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLL-F 206
Query: 209 YVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKE 268
++P V MVF+YS++F AK Q +KI+ + + + S E+ + +E
Sbjct: 207 FIPNVAMVFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAK-------------RE 253
Query: 269 HKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIY 326
KA KTLGI M F + WLP+ + ++ + + VY +L W Y NS NPLIY
Sbjct: 254 RKAAKTLGIAMAAFLVSWLPYLVDAVIDAYMNFITPPYVYEILVWCVYYNSAMNPLIY 311
>gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens]
Length = 432
Score = 167 bits (424), Expect = 1e-41
Identities = 107/328 (32%), Positives = 170/328 (51%), Gaps = 31/328 (9%)
Query: 34 VGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPF-GAA 92
V +G +++LI L + GN LV+ ++ ++L+ +NY I SLA ADL + +AV+PF
Sbjct: 82 VVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVT 141
Query: 93 HILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARV 152
++ W FG+F+C + ++DV+C TASI TLCVI++DRY IT P Y
Sbjct: 142 DLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAK 201
Query: 153 IILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPL 212
+IL VW++S + LP W + + + + C + Y I S+ V+FY+P+
Sbjct: 202 MILSVWLLSASIT-LPPLFGWAQNVNDDKV--------CLISQDFGYTIYSTAVAFYIPM 252
Query: 213 VIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDG---------------RTGHG 257
+M+F+Y ++++ A++ K K G V+ S + +G R
Sbjct: 253 SVMLFMYYQIYKAARKSAAK-HKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKH 311
Query: 258 LRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVI----QDNLIRKEVYILLNW 313
R++ +E KA TLGII+G FT+CWLPFF+++ + I V W
Sbjct: 312 ERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLW 371
Query: 314 IGYVNSGFNPLIYC-RSPDFRIAFQELL 340
+GY NS NP IY + D R ++ LL
Sbjct: 372 LGYANSLINPFIYAFFNRDLRTTYRSLL 399
>gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens]
Length = 479
Score = 167 bits (424), Expect = 1e-41
Identities = 107/328 (32%), Positives = 170/328 (51%), Gaps = 31/328 (9%)
Query: 34 VGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPF-GAA 92
V +G +++LI L + GN LV+ ++ ++L+ +NY I SLA ADL + +AV+PF
Sbjct: 82 VVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVT 141
Query: 93 HILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARV 152
++ W FG+F+C + ++DV+C TASI TLCVI++DRY IT P Y
Sbjct: 142 DLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAK 201
Query: 153 IILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPL 212
+IL VW++S + LP W + + + + C + Y I S+ V+FY+P+
Sbjct: 202 MILSVWLLSASIT-LPPLFGWAQNVNDDKV--------CLISQDFGYTIYSTAVAFYIPM 252
Query: 213 VIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDG---------------RTGHG 257
+M+F+Y ++++ A++ K K G V+ S + +G R
Sbjct: 253 SVMLFMYYQIYKAARKSAAK-HKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKH 311
Query: 258 LRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVI----QDNLIRKEVYILLNW 313
R++ +E KA TLGII+G FT+CWLPFF+++ + I V W
Sbjct: 312 ERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLW 371
Query: 314 IGYVNSGFNPLIYC-RSPDFRIAFQELL 340
+GY NS NP IY + D R ++ LL
Sbjct: 372 LGYANSLINPFIYAFFNRDLRTTYRSLL 399
>gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens]
Length = 445
Score = 167 bits (424), Expect = 1e-41
Identities = 107/328 (32%), Positives = 170/328 (51%), Gaps = 31/328 (9%)
Query: 34 VGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPF-GAA 92
V +G +++LI L + GN LV+ ++ ++L+ +NY I SLA ADL + +AV+PF
Sbjct: 82 VVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSVT 141
Query: 93 HILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARV 152
++ W FG+F+C + ++DV+C TASI TLCVI++DRY IT P Y
Sbjct: 142 DLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQNGKCMAK 201
Query: 153 IILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPL 212
+IL VW++S + LP W + + + + C + Y I S+ V+FY+P+
Sbjct: 202 MILSVWLLSASIT-LPPLFGWAQNVNDDKV--------CLISQDFGYTIYSTAVAFYIPM 252
Query: 213 VIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDG---------------RTGHG 257
+M+F+Y ++++ A++ K K G V+ S + +G R
Sbjct: 253 SVMLFMYYQIYKAARKSAAK-HKFPGFPRVEPDSVIALNGIVKLQKEVEECANLSRLLKH 311
Query: 258 LRRSSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVI----QDNLIRKEVYILLNW 313
R++ +E KA TLGII+G FT+CWLPFF+++ + I V W
Sbjct: 312 ERKNISIFKREQKAATTLGIIVGAFTVCWLPFFLLSTARPFICGTSCSCIPLWVERTFLW 371
Query: 314 IGYVNSGFNPLIYC-RSPDFRIAFQELL 340
+GY NS NP IY + D R ++ LL
Sbjct: 372 LGYANSLINPFIYAFFNRDLRTTYRSLL 399
>gi|21264324 trace amine associated receptor 1 [Homo sapiens]
Length = 339
Score = 167 bits (422), Expect = 2e-41
Identities = 97/307 (31%), Positives = 163/307 (53%), Gaps = 21/307 (6%)
Query: 39 VMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHILMKM 98
+M LI+L + GN++VI +I+ F++L T TN+ I S+A D ++G V+P+
Sbjct: 29 LMVLIILTTLVGNLIVIVSISHFKQLHTPTNWLIHSMATVDFLLGCLVMPYSMVRSAEHC 88
Query: 99 WTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIILMVW 158
W FG +C+ TS D++ +ASI L I++DRY+A+ P +Y++ + V+I + W
Sbjct: 89 WYFGEVFCKIHTSTDIMLSSASIFHLSFISIDRYYAVCDPLRYKAKMNILVICVMIFISW 148
Query: 159 IVSGLTS----FLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVI 214
V + + FL + + + ++C C F ++ + + + SFY+P I
Sbjct: 149 SVPAVFAFGMIFLELNFKGAEEIYYKHVHCRGG---CSVFFSKISGVLTFMTSFYIPGSI 205
Query: 215 MVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRTGHGLRRSSKFCLKEHKALKT 274
M+ VY R++ AK Q + I + + + +G+ +S KE KA+KT
Sbjct: 206 MLCVYYRIYLIAKEQARLISDANQKLQI--------GLEMKNGISQS-----KERKAVKT 252
Query: 275 LGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLIYC-RSPDFR 333
LGI+MG F +CW PFFI ++ +I + +L W GY+NS FNP++Y P FR
Sbjct: 253 LGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFNPMVYAFFYPWFR 312
Query: 334 IAFQELL 340
A + +L
Sbjct: 313 KALKMML 319
>gi|4504545 5-hydroxytryptamine (serotonin) receptor 6 [Homo
sapiens]
Length = 440
Score = 162 bits (409), Expect = 7e-40
Identities = 95/301 (31%), Positives = 153/301 (50%), Gaps = 14/301 (4%)
Query: 32 WVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGA 91
WV + +++ N L+I I L+ +N+F+ SL +DL++GL V+P
Sbjct: 28 WVAA---ALCVVIALTAAANSLLIALICTQPALRNTSNFFLVSLFTSDLMVGLVVMPPAM 84
Query: 92 AHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKAR 151
+ L W C WT+ DV+C +ASI LC+I++DRY I SP +Y+ +T +A
Sbjct: 85 LNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLISLDRYLLILSPLRYKLRMTPLRAL 144
Query: 152 VIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVP 211
++L W ++ L SFLP+ + W+ H C + + + +S ++F++P
Sbjct: 145 ALVLGAWSLAALASFLPLLLGWHELGHARP----PVPGQCRLLASLPFVLVASGLTFFLP 200
Query: 212 LVIMVFVYSRVFQEAKRQ-LQKIDKSEG-RFHVQNLSQVEQDGRTG----HGLRRSSKFC 265
+ F Y R+ A++Q +Q + G QV + R G R ++K
Sbjct: 201 SGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVPRTPRPGVESADSRRLATKHS 260
Query: 266 LKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEVYILLNWIGYVNSGFNPLI 325
K KA TLGI++G F + WLPFF+ NIV + D I ++ +L W+GY NS NP+I
Sbjct: 261 RKALKASLTLGILLGMFFVTWLPFFVANIVQAVCD-CISPGLFDVLTWLGYCNSTMNPII 319
Query: 326 Y 326
Y
Sbjct: 320 Y 320
>gi|10835197 5-hydroxytryptamine (serotonin) receptor 1F [Homo
sapiens]
Length = 366
Score = 159 bits (401), Expect = 6e-39
Identities = 112/348 (32%), Positives = 166/348 (47%), Gaps = 48/348 (13%)
Query: 36 MGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITSLACADLVMGLAVVPFGAAHIL 95
+ + +S + L N LVI AI +L NY I SLA D ++ + V+PF +I+
Sbjct: 26 VSLTLSGLALMTTTINSLVIAAIIVTRKLHHPANYLICSLAVTDFLVAVLVMPFSIVYIV 85
Query: 96 MKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFAITSPFKYQSLLTKNKARVIIL 155
+ W G C+ W S+D+ C T SI L IA+DRY AIT +Y T A ++I
Sbjct: 86 RESWIMGQVVCDIWLSVDITCCTCSILHLSAIALDRYRAITDAVEYARKRTPKHAGIMIT 145
Query: 156 MVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFFTNQAYAIASSIVSFYVPLVIM 215
+VWI+S S P + W HQ ++ C + I S+ +FY+PL ++
Sbjct: 146 IVWIISVFISMPP--LFW---RHQ---GTSRDDECIIKHDHIVSTIYSTFGAFYIPLALI 197
Query: 216 VFVYSRVFQEA-----KRQLQKIDKSEGRFHV-------------------QNLSQVEQD 251
+ +Y ++++ A KRQ +I K E V ++LS D
Sbjct: 198 LILYYKIYRAAKTLYHKRQASRIAKEEVNGQVLLESGEKSTKSVSTSYVLEKSLSDPSTD 257
Query: 252 GRTGHGLRRSSKFCLK--------------EHKALKTLGIIMGTFTLCWLPFFIVN-IVH 296
H RS + K E KA TLG+I+G F +CWLPFF+ +V+
Sbjct: 258 FDKIHSTVRSLRSEFKHEKSWRRQKISGTRERKAATTLGLILGAFVICWLPFFVKELVVN 317
Query: 297 VIQDNLIRKEVYILLNWIGYVNSGFNPLIY-CRSPDFRIAFQELLCLR 343
V I +E+ L W+GY+NS NPLIY + DF+ AFQ+L+ R
Sbjct: 318 VCDKCKISEEMSNFLAWLGYLNSLINPLIYTIFNEDFKKAFQKLVRCR 365
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.325 0.138 0.432
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,085,512
Number of Sequences: 37866
Number of extensions: 627722
Number of successful extensions: 3378
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 512
Number of HSP's successfully gapped in prelim test: 238
Number of HSP's that attempted gapping in prelim test: 1950
Number of HSP's gapped (non-prelim): 943
length of query: 413
length of database: 18,247,518
effective HSP length: 105
effective length of query: 308
effective length of database: 14,271,588
effective search space: 4395649104
effective search space used: 4395649104
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.