Guide to the Human Genome
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Search of human proteins with 4501933

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo
sapiens]
         (375 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo sa...   755   0.0  
gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo sa...   726   0.0  
gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo sa...   710   0.0  
gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit ...   552   e-157
gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo s...   488   e-138
gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens]   480   e-136
gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens]     475   e-134
gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo sap...   460   e-129
gi|156627571 sorbitol dehydrogenase [Homo sapiens]                     94   2e-19
gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a...    63   5e-10
gi|194239674 crystallin, zeta isoform a [Homo sapiens]                 57   2e-08
gi|13236495 crystallin, zeta isoform a [Homo sapiens]                  57   2e-08
gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b...    50   3e-06
gi|194239676 crystallin, zeta isoform b [Homo sapiens]                 49   7e-06
gi|18379349 vesicle amine transport protein 1 [Homo sapiens]           48   1e-05
gi|28557745 zinc binding alcohol dehydrogenase domain containing...    43   5e-04
gi|24308257 vesicle amine transport protein 1 homolog (T. califo...    42   7e-04
gi|41872631 fatty acid synthase [Homo sapiens]                         39   0.010
gi|90669511 crystallin, zeta-like 1 [Homo sapiens]                     37   0.038
gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]       36   0.064
gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]       36   0.064
gi|47519420 reticulon 4 interacting protein 1 precursor [Homo sa...    32   0.93 
gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]        31   2.1  
gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]        31   2.1  
gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]        31   2.1  
gi|194018457 N-acetylgalactosaminyltransferase-like 6 [Homo sapi...    31   2.1  
gi|222831587 tRNA methyltransferase 61 homolog B [Homo sapiens]        29   7.9  

>gi|4501933 class I alcohol dehydrogenase, gamma subunit [Homo
           sapiens]
          Length = 375

 Score =  755 bits (1950), Expect = 0.0
 Identities = 375/375 (100%), Positives = 375/375 (100%)

Query: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVT 60
           MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVT
Sbjct: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVT 60

Query: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120
           PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP
Sbjct: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120

Query: 121 RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180
           RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG
Sbjct: 121 RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180

Query: 181 YGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240
           YGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE
Sbjct: 181 YGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240

Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300
           CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ
Sbjct: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300

Query: 301 NLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGF 360
           NLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGF
Sbjct: 301 NLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGF 360

Query: 361 DLLRSGKSIRTVLTF 375
           DLLRSGKSIRTVLTF
Sbjct: 361 DLLRSGKSIRTVLTF 375


>gi|34577061 class I alcohol dehydrogenase, beta subunit [Homo
           sapiens]
          Length = 375

 Score =  726 bits (1873), Expect = 0.0
 Identities = 354/375 (94%), Positives = 366/375 (97%)

Query: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVT 60
           MSTAGKVIKCKAAVLWE+KKPFSIE+VEVAPPKA+EVRIKMVA GIC +D+HVVSGNLVT
Sbjct: 1   MSTAGKVIKCKAAVLWEVKKPFSIEDVEVAPPKAYEVRIKMVAVGICHTDDHVVSGNLVT 60

Query: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120
           PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCR+CKNPESNYCLKNDLGNP
Sbjct: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRVCKNPESNYCLKNDLGNP 120

Query: 121 RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180
           RGTLQDGTRRFTC GKPIHHF+G STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG
Sbjct: 121 RGTLQDGTRRFTCRGKPIHHFLGTSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180

Query: 181 YGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240
           YGSAV VAKVTPGSTCAVFGLGGVGLS VMGCKAAGAARIIAVDINKDKFAKAKELGATE
Sbjct: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240

Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300
           CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPP SQ
Sbjct: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPASQ 300

Query: 301 NLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGF 360
           NLSINPMLLLTGRTWKGA++GGFKSKE +PKLVADFMAKKFSLDALIT++LPFEKINEGF
Sbjct: 301 NLSINPMLLLTGRTWKGAVYGGFKSKEGIPKLVADFMAKKFSLDALITHVLPFEKINEGF 360

Query: 361 DLLRSGKSIRTVLTF 375
           DLL SGKSIRTVLTF
Sbjct: 361 DLLHSGKSIRTVLTF 375


>gi|4501929 class I alcohol dehydrogenase, alpha subunit [Homo
           sapiens]
          Length = 375

 Score =  710 bits (1833), Expect = 0.0
 Identities = 348/375 (92%), Positives = 360/375 (96%)

Query: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVT 60
           MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVA GIC +D+HVVSG +VT
Sbjct: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAVGICGTDDHVVSGTMVT 60

Query: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120
           PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPL  PQCGKCRICKNPESNYCLKND+ NP
Sbjct: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLAIPQCGKCRICKNPESNYCLKNDVSNP 120

Query: 121 RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180
           +GTLQDGT RFTC  KPIHHF+G+STFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG
Sbjct: 121 QGTLQDGTSRFTCRRKPIHHFLGISTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180

Query: 181 YGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240
           YGSAV VAKVTPGSTCAVFGLGGVGLS +MGCKAAGAARIIAVDINKDKFAKAKELGATE
Sbjct: 181 YGSAVNVAKVTPGSTCAVFGLGGVGLSAIMGCKAAGAARIIAVDINKDKFAKAKELGATE 240

Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300
           CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ
Sbjct: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300

Query: 301 NLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGF 360
           NLS+NPMLLLTGRTWKGAI GGFKSKE VPKLVADFMAKKFSLDALIT++LPFEKINEGF
Sbjct: 301 NLSMNPMLLLTGRTWKGAILGGFKSKECVPKLVADFMAKKFSLDALITHVLPFEKINEGF 360

Query: 361 DLLRSGKSIRTVLTF 375
           DLL SGKSIRT+L F
Sbjct: 361 DLLHSGKSIRTILMF 375


>gi|71743840 class IV alcohol dehydrogenase, mu or sigma subunit
           [Homo sapiens]
          Length = 386

 Score =  552 bits (1422), Expect = e-157
 Identities = 259/375 (69%), Positives = 314/375 (83%), Gaps = 1/375 (0%)

Query: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVT 60
           M TAGKVIKCKAAVLWE K+PFSIEE+EVAPPK  EVRIK++A GICR+D+HV+ G +V+
Sbjct: 13  MGTAGKVIKCKAAVLWEQKQPFSIEEIEVAPPKTKEVRIKILATGICRTDDHVIKGTMVS 72

Query: 61  PLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120
             PVI+GHEA GIVES+GEGVTTVKPGDKVIPLF PQC +C  C+NP+ N C+++D+   
Sbjct: 73  KFPVIVGHEATGIVESIGEGVTTVKPGDKVIPLFLPQCRECNACRNPDGNLCIRSDITG- 131

Query: 121 RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180
           RG L DGT RFTC GKP+HHF+  STF++YTVVDE++VAKID A+P EKVCLIGCGFSTG
Sbjct: 132 RGVLADGTTRFTCKGKPVHHFMNTSTFTEYTVVDESSVAKIDDAAPPEKVCLIGCGFSTG 191

Query: 181 YGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240
           YG+AVK  KV PGSTC VFGLGGVGLSV+MGCK+AGA+RII +D+NKDKF KA  +GATE
Sbjct: 192 YGAAVKTGKVKPGSTCVVFGLGGVGLSVIMGCKSAGASRIIGIDLNKDKFEKAMAVGATE 251

Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300
           CI+P+D  KPI EVL EMT   V ++FEVIG L+TM+ +L  CH   GTSV+VGVPP ++
Sbjct: 252 CISPKDSTKPISEVLSEMTGNNVGYTFEVIGHLETMIDALASCHMNYGTSVVVGVPPSAK 311

Query: 301 NLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGF 360
            L+ +PMLL TGRTWKG +FGG KS++ VPKLV +F+AKKF LD LIT++LPF+KI+EGF
Sbjct: 312 MLTYDPMLLFTGRTWKGCVFGGLKSRDDVPKLVTEFLAKKFDLDQLITHVLPFKKISEGF 371

Query: 361 DLLRSGKSIRTVLTF 375
           +LL SG+SIRTVLTF
Sbjct: 372 ELLNSGQSIRTVLTF 386


>gi|71565154 class III alcohol dehydrogenase, chi subunit [Homo
           sapiens]
          Length = 374

 Score =  488 bits (1257), Expect = e-138
 Identities = 235/373 (63%), Positives = 290/373 (77%), Gaps = 5/373 (1%)

Query: 4   AGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP-- 61
           A +VIKCKAAV WE  KP SIEE+EVAPPKAHEVRIK++A  +C +D + +SG    P  
Sbjct: 2   ANEVIKCKAAVAWEAGKPLSIEEIEVAPPKAHEVRIKIIATAVCHTDAYTLSG--ADPEG 59

Query: 62  -LPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNP 120
             PVILGHE AGIVESVGEGVT +K GD VIPL+ PQCG+C+ C NP++N C K  +   
Sbjct: 60  CFPVILGHEGAGIVESVGEGVTKLKAGDTVIPLYIPQCGECKFCLNPKTNLCQKIRVTQG 119

Query: 121 RGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTG 180
           +G + DGT RFTC GK I H++G STFS+YTVV + +VAKID  +PL+KVCL+GCG STG
Sbjct: 120 KGLMPDGTSRFTCKGKTILHYMGTSTFSEYTVVADISVAKIDPLAPLDKVCLLGCGISTG 179

Query: 181 YGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATE 240
           YG+AV  AK+ PGS CAVFGLGGVGL+V+MGCK AGA+RII VDINKDKFA+AKE GATE
Sbjct: 180 YGAAVNTAKLEPGSVCAVFGLGGVGLAVIMGCKVAGASRIIGVDINKDKFARAKEFGATE 239

Query: 241 CINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQ 300
           CINPQD+ KPIQEVL EMTDGGVD+SFE IG +  M A+L  CH+  G SV+VGV    +
Sbjct: 240 CINPQDFSKPIQEVLIEMTDGGVDYSFECIGNVKVMRAALEACHKGWGVSVVVGVAASGE 299

Query: 301 NLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGF 360
            ++  P  L+TGRTWKG  FGG+KS ESVPKLV+++M+KK  +D  +T+ L F++IN+ F
Sbjct: 300 EIATRPFQLVTGRTWKGTAFGGWKSVESVPKLVSEYMSKKIKVDEFVTHNLSFDEINKAF 359

Query: 361 DLLRSGKSIRTVL 373
           +L+ SGKSIRTV+
Sbjct: 360 ELMHSGKSIRTVV 372


>gi|156523966 class V alcohol dehydrogenase isoform 1 [Homo sapiens]
          Length = 375

 Score =  480 bits (1236), Expect = e-136
 Identities = 237/374 (63%), Positives = 293/374 (78%), Gaps = 2/374 (0%)

Query: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVV-SGNLV 59
           MST G+VI+CKAA+LW+   PFSIEEVEVAPPKA EVRIK+VA G+C ++  V+ S +L 
Sbjct: 1   MSTTGQVIRCKAAILWKPGAPFSIEEVEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLD 60

Query: 60  TPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGN 119
              P ILGHE AGIVES+GEGV+TVKPGDKVI LF PQCG+C  C N E N+C++     
Sbjct: 61  LLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSK 120

Query: 120 PRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179
            +  + DGT RFTC GK I+HF   STF +YTV+ E +VAKIDA +PLEKVCLI CGFST
Sbjct: 121 TQ-LMSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFST 179

Query: 180 GYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239
           G+G+A+  AKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARII VD+NK+KF KA+ELGAT
Sbjct: 180 GFGAAINTAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGAT 239

Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299
           EC+NPQD KKPIQEVL +MTD G+DF FE IG LD + A+L  C+E+ G  V+VGV P S
Sbjct: 240 ECLNPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLPAS 299

Query: 300 QNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEG 359
             L I+  L  +GR+ KG++FGG+KS++ +PKLVAD+MA+K +LD LIT+ L  +KINE 
Sbjct: 300 VQLKISGQLFFSGRSLKGSVFGGWKSRQHIPKLVADYMAEKLNLDPLITHTLNLDKINEA 359

Query: 360 FDLLRSGKSIRTVL 373
            +L+++GK IR +L
Sbjct: 360 VELMKTGKCIRCIL 373


>gi|4501939 class V alcohol dehydrogenase isoform 2 [Homo sapiens]
          Length = 368

 Score =  475 bits (1222), Expect = e-134
 Identities = 234/368 (63%), Positives = 289/368 (78%), Gaps = 2/368 (0%)

Query: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVV-SGNLV 59
           MST G+VI+CKAA+LW+   PFSIEEVEVAPPKA EVRIK+VA G+C ++  V+ S +L 
Sbjct: 1   MSTTGQVIRCKAAILWKPGAPFSIEEVEVAPPKAKEVRIKVVATGLCGTEMKVLGSKHLD 60

Query: 60  TPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGN 119
              P ILGHE AGIVES+GEGV+TVKPGDKVI LF PQCG+C  C N E N+C++     
Sbjct: 61  LLYPTILGHEGAGIVESIGEGVSTVKPGDKVITLFLPQCGECTSCLNSEGNFCIQFKQSK 120

Query: 120 PRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFST 179
            +  + DGT RFTC GK I+HF   STF +YTV+ E +VAKIDA +PLEKVCLI CGFST
Sbjct: 121 TQ-LMSDGTSRFTCKGKSIYHFGNTSTFCEYTVIKEISVAKIDAVAPLEKVCLISCGFST 179

Query: 180 GYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGAT 239
           G+G+A+  AKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARII VD+NK+KF KA+ELGAT
Sbjct: 180 GFGAAINTAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIGVDVNKEKFKKAQELGAT 239

Query: 240 ECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDS 299
           EC+NPQD KKPIQEVL +MTD G+DF FE IG LD + A+L  C+E+ G  V+VGV P S
Sbjct: 240 ECLNPQDLKKPIQEVLFDMTDAGIDFCFEAIGNLDVLAAALASCNESYGVCVVVGVLPAS 299

Query: 300 QNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEG 359
             L I+  L  +GR+ KG++FGG+KS++ +PKLVAD+MA+K +LD LIT+ L  +KINE 
Sbjct: 300 VQLKISGQLFFSGRSLKGSVFGGWKSRQHIPKLVADYMAEKLNLDPLITHTLNLDKINEA 359

Query: 360 FDLLRSGK 367
            +L+++GK
Sbjct: 360 VELMKTGK 367


>gi|71565152 class II alcohol dehydrogenase, pi subunit [Homo
           sapiens]
          Length = 380

 Score =  460 bits (1183), Expect = e-129
 Identities = 227/380 (59%), Positives = 283/380 (74%), Gaps = 5/380 (1%)

Query: 1   MSTAGKVIKCKAAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLV- 59
           M T GKVIKCKAA+ WE  KP  IEEVEVAPPKAHEVRI+++A  +C +D  V+      
Sbjct: 1   MGTKGKVIKCKAAIAWEAGKPLCIEEVEVAPPKAHEVRIQIIATSLCHTDATVIDSKFEG 60

Query: 60  TPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLK-NDLG 118
              PVI+GHEAAGIVES+G GVT VKPGDKVIPL+ P C KC+ C +P +N C K ++L 
Sbjct: 61  LAFPVIVGHEAAGIVESIGPGVTNVKPGDKVIPLYAPLCRKCKFCLSPLTNLCGKISNLK 120

Query: 119 NPRGT---LQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGC 175
           +P      ++D T RFTC GKP++HF G STFSQYTVV +  +AKID  + LE+VCL+GC
Sbjct: 121 SPASDQQLMEDKTSRFTCKGKPVYHFFGTSTFSQYTVVSDINLAKIDDDANLERVCLLGC 180

Query: 176 GFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKE 235
           GFSTGYG+A+  AKVTPGSTCAVFGLGGVGLS VMGCKAAGA+RII +DIN +KF KAK 
Sbjct: 181 GFSTGYGAAINNAKVTPGSTCAVFGLGGVGLSAVMGCKAAGASRIIGIDINSEKFVKAKA 240

Query: 236 LGATECINPQDYKKPIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGV 295
           LGAT+C+NP+D  KPIQEV+ E+T GGVDF+ +  G  +TM A+L C     G+   +GV
Sbjct: 241 LGATDCLNPRDLHKPIQEVIIELTKGGVDFALDCAGGSETMKAALDCTTAGWGSCTFIGV 300

Query: 296 PPDSQNLSINPMLLLTGRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEK 355
              S+ L+I P  L+ GRT  G  FGG+KS +S+PKLV D+  KKF+LDAL+T+ LPF+K
Sbjct: 301 AAGSKGLTIFPEELIIGRTINGTFFGGWKSVDSIPKLVTDYKNKKFNLDALVTHTLPFDK 360

Query: 356 INEGFDLLRSGKSIRTVLTF 375
           I+E FDL+  GKS+RT+L F
Sbjct: 361 ISEAFDLMNQGKSVRTILIF 380


>gi|156627571 sorbitol dehydrogenase [Homo sapiens]
          Length = 357

 Score = 94.0 bits (232), Expect = 2e-19
 Identities = 92/362 (25%), Positives = 156/362 (43%), Gaps = 47/362 (12%)

Query: 24  IEEVEVAPPKAHEVRIKMVAAGICRSDEHVVS----GNLVTPLPVILGHEAAGIVESVGE 79
           +E   +  P  +EV ++M + GIC SD H       GN +   P++LGHEA+G VE VG 
Sbjct: 22  LENYPIPEPGPNEVLLRMHSVGICGSDVHYWEYGRIGNFIVKKPMVLGHEASGTVEKVGS 81

Query: 80  GVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKP-- 137
            V  +KPGD+V                 E     +ND     G        F C+  P  
Sbjct: 82  SVKHLKPGDRVA---------------IEPGAPRENDEFCKMGRYNLSPSIFFCATPPDD 126

Query: 138 --IHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGST 195
             +  F   +    Y + D     +     PL          S G   A +   VT G  
Sbjct: 127 GNLCRFYKHNAAFCYKLPDNVTFEEGALIEPL----------SVGI-HACRRGGVTLGHK 175

Query: 196 CAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVL 255
             V G G +G+  ++  KA GAA+++  D++  + +KAKE+GA   +  Q  K+  QE+ 
Sbjct: 176 VLVCGAGPIGMVTLLVAKAMGAAQVVVTDLSATRLSKAKEIGADLVL--QISKESPQEIA 233

Query: 256 KEMTDGGV----DFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLLLT 311
           +++ +G +    + + E  G   ++ A +       G  V+VG+  +     +  + LL 
Sbjct: 234 RKV-EGQLGCKPEVTIECTGAEASIQAGIYATRSG-GNLVLVGLGSE-----MTTVPLLH 286

Query: 312 GRTWKGAIFGGFKSKESVPKLVADFMAKKFSLDALITNILPFEKINEGFDLLRSGKSIRT 371
               +  I G F+   + P  ++   +K  ++  L+T+  P EK  E F+  + G  ++ 
Sbjct: 287 AAIREVDIKGVFRYCNTWPVAISMLASKSVNVKPLVTHRFPLEKALEAFETFKKGLGLKI 346

Query: 372 VL 373
           +L
Sbjct: 347 ML 348


>gi|67078404 trans-2-enoyl-CoA reductase, mitochondrial isoform a
           [Homo sapiens]
          Length = 373

 Score = 62.8 bits (151), Expect = 5e-10
 Identities = 62/247 (25%), Positives = 99/247 (40%), Gaps = 56/247 (22%)

Query: 20  KPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSGN--LVTPLPVILGHEAAGIVESV 77
           K   ++ +E+A  +  +VR+KM+AA I  SD +++ GN   +  LP + G+E    V +V
Sbjct: 56  KVVELKNLELAAVRGSDVRVKMLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAV 115

Query: 78  GEGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKP 137
           G  VT +KPGD VIP                                             
Sbjct: 116 GSNVTGLKPGDWVIPA-------------------------------------------- 131

Query: 138 IHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPG-STC 196
                G+ T+    V  E A+ ++ +  PL+    +G    T Y   +   ++ PG S  
Sbjct: 132 ---NAGLGTWRTEAVFSEEALIQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVI 188

Query: 197 AVFGLGGVGLSVVMGCKAAGAARIIAV----DINKDKFAKAKELGATECINPQDYKKP-I 251
                 GVG +V+    A G   I  V    DI K    + K LGA   I  ++ ++P +
Sbjct: 189 QNASNSGVGQAVIQIAAALGLRTINVVRDRPDIQK-LSDRLKSLGAEHVITEEELRRPEM 247

Query: 252 QEVLKEM 258
           +   K+M
Sbjct: 248 KNFFKDM 254


>gi|194239674 crystallin, zeta isoform a [Homo sapiens]
          Length = 329

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 65/284 (22%), Positives = 114/284 (40%), Gaps = 57/284 (20%)

Query: 26  EVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP--LPVILGHEAAGIVESVGEGVTT 83
           ++ V  PK H+V IK+ A G+   + ++ SG       LP   G + AG++E+VG+  + 
Sbjct: 27  DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASA 86

Query: 84  VKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVG 143
            K GD+V   FT                                    T SG        
Sbjct: 87  FKKGDRV---FTSS----------------------------------TISG-------- 101

Query: 144 VSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGL-G 202
              +++Y +  ++ V K+      ++   IG  + T Y + +  A V  G +  V G  G
Sbjct: 102 --GYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASG 159

Query: 203 GVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGG 262
           GVGL+     +A G  +I+     ++      + GA E  N ++    I ++ K + + G
Sbjct: 160 GVGLAACQIARAYG-LKILGTAGTEEGQKIVLQNGAHEVFNHREVNY-IDKIKKYVGEKG 217

Query: 263 VDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINP 306
           +D   E++  ++      L  H   G  ++VG       + INP
Sbjct: 218 IDIIIEMLANVNLSKDLSLLSHG--GRVIVVG---SRGTIEINP 256


>gi|13236495 crystallin, zeta isoform a [Homo sapiens]
          Length = 329

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 65/284 (22%), Positives = 114/284 (40%), Gaps = 57/284 (20%)

Query: 26  EVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP--LPVILGHEAAGIVESVGEGVTT 83
           ++ V  PK H+V IK+ A G+   + ++ SG       LP   G + AG++E+VG+  + 
Sbjct: 27  DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASA 86

Query: 84  VKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVG 143
            K GD+V   FT                                    T SG        
Sbjct: 87  FKKGDRV---FTSS----------------------------------TISG-------- 101

Query: 144 VSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGL-G 202
              +++Y +  ++ V K+      ++   IG  + T Y + +  A V  G +  V G  G
Sbjct: 102 --GYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASG 159

Query: 203 GVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKPIQEVLKEMTDGG 262
           GVGL+     +A G  +I+     ++      + GA E  N ++    I ++ K + + G
Sbjct: 160 GVGLAACQIARAYG-LKILGTAGTEEGQKIVLQNGAHEVFNHREVNY-IDKIKKYVGEKG 217

Query: 263 VDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINP 306
           +D   E++  ++      L  H   G  ++VG       + INP
Sbjct: 218 IDIIIEMLANVNLSKDLSLLSHG--GRVIVVG---SRGTIEINP 256


>gi|67078406 trans-2-enoyl-CoA reductase, mitochondrial isoform b
           [Homo sapiens]
          Length = 297

 Score = 50.1 bits (118), Expect = 3e-06
 Identities = 56/226 (24%), Positives = 86/226 (38%), Gaps = 56/226 (24%)

Query: 41  MVAAGICRSDEHVVSGN--LVTPLPVILGHEAAGIVESVGEGVTTVKPGDKVIPLFTPQC 98
           M+AA I  SD +++ GN   +  LP + G+E    V +VG  VT +KPGD VIP      
Sbjct: 1   MLAAPINPSDINMIQGNYGFLPELPAVGGNEGVAQVVAVGSNVTGLKPGDWVIPA----- 55

Query: 99  GKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQYTVVDENAV 158
                                                       G+ T+    V  E A+
Sbjct: 56  ------------------------------------------NAGLGTWRTEAVFSEEAL 73

Query: 159 AKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPG-STCAVFGLGGVGLSVVMGCKAAGA 217
            ++ +  PL+    +G    T Y   +   ++ PG S        GVG +V+    A G 
Sbjct: 74  IQVPSDIPLQSAATLGVNPCTAYRMLMDFEQLQPGDSVIQNASNSGVGQAVIQIAAALGL 133

Query: 218 ARIIAV----DINKDKFAKAKELGATECINPQDYKKP-IQEVLKEM 258
             I  V    DI K    + K LGA   I  ++ ++P ++   K+M
Sbjct: 134 RTINVVRDRPDIQK-LSDRLKSLGAEHVITEEELRRPEMKNFFKDM 178


>gi|194239676 crystallin, zeta isoform b [Homo sapiens]
          Length = 295

 Score = 48.9 bits (115), Expect = 7e-06
 Identities = 47/194 (24%), Positives = 77/194 (39%), Gaps = 50/194 (25%)

Query: 26  EVEVAPPKAHEVRIKMVAAGICRSDEHVVSGNLVTP--LPVILGHEAAGIVESVGEGVTT 83
           ++ V  PK H+V IK+ A G+   + ++ SG       LP   G + AG++E+VG+  + 
Sbjct: 27  DIAVPIPKDHQVLIKVHACGVNPVETYIRSGTYSRKPLLPYTPGSDVAGVIEAVGDNASA 86

Query: 84  VKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVG 143
            K GD+V   FT                                    T SG        
Sbjct: 87  FKKGDRV---FTSS----------------------------------TISG-------- 101

Query: 144 VSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGL-G 202
              +++Y +  ++ V K+      ++   IG  + T Y + +  A V  G +  V G  G
Sbjct: 102 --GYAEYALAADHTVYKLPEKLDFKQGAAIGIPYFTAYRALIHSACVKAGESVLVHGASG 159

Query: 203 GVGLSVVMGCKAAG 216
           GVGL+     +A G
Sbjct: 160 GVGLAACQIARAYG 173


>gi|18379349 vesicle amine transport protein 1 [Homo sapiens]
          Length = 393

 Score = 48.1 bits (113), Expect = 1e-05
 Identities = 86/371 (23%), Positives = 137/371 (36%), Gaps = 89/371 (23%)

Query: 32  PKAHEVRIKMVAAGICRSDEHVVSG--NLVTPLPVILGHEAAGIVESVGEGVTTVKPGDK 89
           P   ++ +++ A G+  +D     G  + + PLPV  G E AG+V +VGEGV+  K GD+
Sbjct: 74  PGPGQLTLRLRACGLNFADLMARQGLYDRLPPLPVTPGMEGAGVVIAVGEGVSDRKAGDR 133

Query: 90  VIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPIHHFVGVSTFSQ 149
           V+ L                         N  G  Q+                 V TF  
Sbjct: 134 VMVL-------------------------NRSGMWQEEVT-----------VPSVQTF-- 155

Query: 150 YTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAV-FGLGGVGLSV 208
                      I  A   E+   +   + T Y        + PG +  V    GGVG++ 
Sbjct: 156 ----------LIPEAMTFEEAAALLVNYITAYMVLFDFGNLQPGHSVLVHMAAGGVGMAA 205

Query: 209 VMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDY-KKPIQEVLKEMTDGGVDFSF 267
           V  C+      +     +  K    KE G T   +P DY      + +K+++  GVD   
Sbjct: 206 VQLCRTVENVTVFGT-ASASKHEALKENGVT---HPIDYHTTDYVDEIKKISPKGVDIVM 261

Query: 268 EVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPM--LLLTGRTW---------- 315
           + +G  DT     L   +  G  V  G+     NL   P   L+   RTW          
Sbjct: 262 DPLGGSDTAKGYNLL--KPMGKVVTYGM----ANLLTGPKRNLMALARTWWNQFSVTALQ 315

Query: 316 ----KGAIFG---GFKSKESVPKLVADFMAKKFSL------DALITNILPFEKINEGFDL 362
                 A+ G   G+   E   +LV+  +A+  +L         I ++ PFEK+ +    
Sbjct: 316 LLQANRAVCGFHLGYLDGE--VELVSGVVARLLALYNQGHIKPHIDSVWPFEKVADAMKQ 373

Query: 363 LRSGKSIRTVL 373
           ++  K++  VL
Sbjct: 374 MQEKKNVGKVL 384


>gi|28557745 zinc binding alcohol dehydrogenase domain containing 2
           [Homo sapiens]
          Length = 377

 Score = 42.7 bits (99), Expect = 5e-04
 Identities = 35/132 (26%), Positives = 59/132 (44%), Gaps = 6/132 (4%)

Query: 141 FVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFG 200
           ++   +F++YTVV  +    + +  P E + L+  G +T Y S  ++  ++ G    V  
Sbjct: 123 YMAPGSFAEYTVVPASIATPVPSVKP-EYLTLLVSG-TTAYISLKELGGLSEGKKVLVTA 180

Query: 201 LGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYK-KPIQEVLKEMT 259
             G      M         +I    + +K A  K LG   C  P +YK +P+  VLK+  
Sbjct: 181 AAGGTGQFAMQLSKKAKCHVIGTCSSDEKSAFLKSLG---CDRPINYKTEPVGTVLKQEY 237

Query: 260 DGGVDFSFEVIG 271
             GVD  +E +G
Sbjct: 238 PEGVDVVYESVG 249


>gi|24308257 vesicle amine transport protein 1 homolog (T.
           californica)-like [Homo sapiens]
          Length = 419

 Score = 42.4 bits (98), Expect = 7e-04
 Identities = 26/88 (29%), Positives = 46/88 (52%), Gaps = 2/88 (2%)

Query: 32  PKAHEVRIKMVAAGICRSDEHVVSGNLVTP--LPVILGHEAAGIVESVGEGVTTVKPGDK 89
           P+  E++I++ A G+   D  V  GN+  P   P++ G E +GIVE++G+ V   + GD+
Sbjct: 66  PQDGELKIRVKACGLNFIDLMVRQGNIDNPPKTPLVPGFECSGIVEALGDSVKGYEIGDR 125

Query: 90  VIPLFTPQCGKCRICKNPESNYCLKNDL 117
           V+           +C   E  Y + +D+
Sbjct: 126 VMAFVNYNAWAEVVCTPVEFVYKIPDDM 153


>gi|41872631 fatty acid synthase [Homo sapiens]
          Length = 2511

 Score = 38.5 bits (88), Expect = 0.010
 Identities = 46/199 (23%), Positives = 81/199 (40%), Gaps = 7/199 (3%)

Query: 134  SGKPIHHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPG 193
            SGK +   V     +   ++  + +  + +   LE+   +   +ST Y + V   +V PG
Sbjct: 1609 SGKRVMGLVPAKGLATSVLLSPDFLWDVPSNWTLEEAASVPVVYSTAYYALVVRGRVRPG 1668

Query: 194  STCAVF-GLGGVGLSVVMGCKAAGAARIIAV-DINKDKFAKAK--ELGATECINPQDYKK 249
             T  +  G GGVG + +    + G      V    K  + +A+  +L +T   N +D   
Sbjct: 1669 ETLLIHSGSGGVGQAAIAIALSLGCRVFTTVGSAEKRAYLQARFPQLDSTSFANSRDTSF 1728

Query: 250  PIQEVLKEMTDGGVDFSFEVIGRLDTMMASLLCCHEACGTSVIVGVPPDSQNLSINPMLL 309
              Q VL      GVD     +   + + AS+ C     G  + +G    SQN  +   + 
Sbjct: 1729 E-QHVLWHTGGKGVDLVLNSLAE-EKLQASVRCL-ATHGRFLEIGKFDLSQNHPLGMAIF 1785

Query: 310  LTGRTWKGAIFGGFKSKES 328
            L   T+ G +   F ++ S
Sbjct: 1786 LKNVTFHGVLLDAFFNESS 1804


>gi|90669511 crystallin, zeta-like 1 [Homo sapiens]
          Length = 349

 Score = 36.6 bits (83), Expect = 0.038
 Identities = 43/162 (26%), Positives = 68/162 (41%), Gaps = 18/162 (11%)

Query: 66  LGHEAAGIVESVGEGVTTVKPGDKVI---PLFTPQCGKCRICKNPESNYCLKND---LGN 119
           +G E AGIV  VG  V+  +P D+V+   PL +   G C + +  E     K +      
Sbjct: 62  VGREIAGIVLDVGSKVSFFQPDDEVVGILPLDSEDPGLCEVVRVHEHYLVHKPEKVTWTE 121

Query: 120 PRGTLQDGTRRFTC--------SGKPIHHFVGVSTFSQYTV-VDENAVAKI--DAASPLE 168
             G+++DG R +T          GK +    G S F    + +  +  AK+   A S  +
Sbjct: 122 AAGSIRDGVRAYTALHYLSHLSPGKSVLIMDGASAFGTIAIQLAHHRGAKVISTACSLED 181

Query: 169 KVCLIGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVVM 210
           K CL            V   KV    +C +   GG+G+ +V+
Sbjct: 182 KQCLERFRPPIARVIDVSNGKVHVAESC-LEETGGLGVDIVL 222


>gi|22538446 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 35.8 bits (81), Expect = 0.064
 Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 7/127 (5%)

Query: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVF-GLGGVGL 206
           +QY  V E  +  I     L +   I   + T +     V  V  G    +  GL GVG 
Sbjct: 96  AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155

Query: 207 SVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264
           + +   + AGA  ++     K K   A++LGA    N   YKK    +  LK     GV+
Sbjct: 156 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 211

Query: 265 FSFEVIG 271
              + IG
Sbjct: 212 LILDCIG 218


>gi|22538444 tumor protein p53 inducible protein 3 [Homo sapiens]
          Length = 332

 Score = 35.8 bits (81), Expect = 0.064
 Identities = 35/127 (27%), Positives = 51/127 (40%), Gaps = 7/127 (5%)

Query: 148 SQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVAKVTPGSTCAVF-GLGGVGL 206
           +QY  V E  +  I     L +   I   + T +     V  V  G    +  GL GVG 
Sbjct: 96  AQYVTVPEGLLMPIPEGLTLTQAAAIPEAWLTAFQLLHLVGNVQAGDYVLIHAGLSGVGT 155

Query: 207 SVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKKP--IQEVLKEMTDGGVD 264
           + +   + AGA  ++     K K   A++LGA    N   YKK    +  LK     GV+
Sbjct: 156 AAIQLTRMAGAIPLVTAGSQK-KLQMAEKLGAAAGFN---YKKEDFSEATLKFTKGAGVN 211

Query: 265 FSFEVIG 271
              + IG
Sbjct: 212 LILDCIG 218


>gi|47519420 reticulon 4 interacting protein 1 precursor [Homo
           sapiens]
          Length = 396

 Score = 32.0 bits (71), Expect = 0.93
 Identities = 89/363 (24%), Positives = 132/363 (36%), Gaps = 92/363 (25%)

Query: 35  HEVRIKMVAAGICRSDEHVVSGNLVTPL----------------PVILGHEAAGIVESVG 78
           +EV +K+ AA +   D ++ SG   T L                P+ LG + +G+V   G
Sbjct: 72  NEVIVKVHAASVNPIDVNMRSGYGATALNMKRDPLHVKIKGEEFPLTLGRDVSGVVMECG 131

Query: 79  EGVTTVKPGDKVIPLFTPQCGKCRICKNPESNYCLKNDLGNPRGTLQDGTRRFTCSGKPI 138
             V   KPGD+V     P                        +GTL +       SG  +
Sbjct: 132 LDVKYFKPGDEVWAAVPPW----------------------KQGTLSEFV---VVSGNEV 166

Query: 139 HHFVGVSTFSQYTVVDENAVAKIDAASPLEKVCLIGCGFSTGYGSAVKVA----KVTPGS 194
            H     T +Q              A+ L  V L      T + +  KV     K   G 
Sbjct: 167 SHKPKSLTHTQ--------------AASLPYVAL------TAWSAINKVGGLNDKNCTGK 206

Query: 195 TCAVFGL-GGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKELGATECINPQDYKK-PIQ 252
              + G  GGVG   +   K A  A + AV  ++D     ++LGA + I   DYK   ++
Sbjct: 207 RVLILGASGGVGTFAIQVMK-AWDAHVTAV-CSQDASELVRKLGADDVI---DYKSGSVE 261

Query: 253 EVLKEMTDGGVDFSFE-VIGRLDTMMASLLCCHEACGTSVIVGVPP---DSQNLSINPML 308
           E LK +     DF  + V G  +T     L   +  G + +  V P   +   L I   +
Sbjct: 262 EQLKSLKP--FDFILDNVGGSTETWAPDFL--KKWSGATYVTLVTPFLLNMDRLGIADGM 317

Query: 309 LLTGRT---------WKGAIFGGFKSKESVPKL--VADFMAKKFSLDALITNILPFEKIN 357
           L TG T         WKG  +       S P L  +A+ +     +  +I    PF K+ 
Sbjct: 318 LQTGVTVGSKALKHFWKGVHYRWAFFMASGPCLDDIAE-LVDAGKIRPVIEQTFPFSKVP 376

Query: 358 EGF 360
           E F
Sbjct: 377 EAF 379


>gi|226059159 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 17/107 (15%)

Query: 173 IGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVV------MGCKAAGAARIIAVDIN 226
           +G    T Y   +++  V  G T  V    G   SVV       GCK  GA        +
Sbjct: 122 VGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVG------S 175

Query: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG 271
            +K A  ++LG     N   YK  + ++E LK+ +  G D  F+ +G
Sbjct: 176 DEKVAYLQKLGFDVVFN---YKTVESLEETLKKASPDGYDCYFDNVG 219


>gi|226059133 prostaglandin reductase 1 isoform 1 [Homo sapiens]
          Length = 329

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 17/107 (15%)

Query: 173 IGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVV------MGCKAAGAARIIAVDIN 226
           +G    T Y   +++  V  G T  V    G   SVV       GCK  GA        +
Sbjct: 122 VGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVG------S 175

Query: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG 271
            +K A  ++LG     N   YK  + ++E LK+ +  G D  F+ +G
Sbjct: 176 DEKVAYLQKLGFDVVFN---YKTVESLEETLKKASPDGYDCYFDNVG 219


>gi|226056130 prostaglandin reductase 1 isoform 2 [Homo sapiens]
          Length = 301

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 30/107 (28%), Positives = 45/107 (42%), Gaps = 17/107 (15%)

Query: 173 IGCGFSTGYGSAVKVAKVTPGSTCAVFGLGGVGLSVV------MGCKAAGAARIIAVDIN 226
           +G    T Y   +++  V  G T  V    G   SVV       GCK  GA        +
Sbjct: 122 VGMPGLTAYFGLLEICGVKGGETVMVNAAAGAVGSVVGQIAKLKGCKVVGAVG------S 175

Query: 227 KDKFAKAKELGATECINPQDYK--KPIQEVLKEMTDGGVDFSFEVIG 271
            +K A  ++LG     N   YK  + ++E LK+ +  G D  F+ +G
Sbjct: 176 DEKVAYLQKLGFDVVFN---YKTVESLEETLKKASPDGYDCYFDNVG 219


>gi|194018457 N-acetylgalactosaminyltransferase-like 6 [Homo
           sapiens]
          Length = 601

 Score = 30.8 bits (68), Expect = 2.1
 Identities = 20/57 (35%), Positives = 28/57 (49%), Gaps = 10/57 (17%)

Query: 6   KVIKCK------AAVLWELKKPFSIEEVEVAPPKAHEVRIKMVAAGICRSDEHVVSG 56
           K +KCK      AAV W++ K +      V PP A    I+ VAA +C   +H  +G
Sbjct: 423 KQLKCKDFKWFMAAVAWDVPKYYP----PVEPPPAAWGEIRNVAANLCVDSKHGATG 475


>gi|222831587 tRNA methyltransferase 61 homolog B [Homo sapiens]
          Length = 477

 Score = 28.9 bits (63), Expect = 7.9
 Identities = 13/46 (28%), Positives = 22/46 (47%)

Query: 190 VTPGSTCAVFGLGGVGLSVVMGCKAAGAARIIAVDINKDKFAKAKE 235
           + PG T    G G  G+S+ +        R+I+ ++ KD    AK+
Sbjct: 244 INPGDTVLEAGSGSGGMSLFLSKAVGSQGRVISFEVRKDHHDLAKK 289


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.320    0.137    0.412 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,345,438
Number of Sequences: 37866
Number of extensions: 628288
Number of successful extensions: 1408
Number of sequences better than 10.0: 27
Number of HSP's better than 10.0 without gapping: 17
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 1375
Number of HSP's gapped (non-prelim): 32
length of query: 375
length of database: 18,247,518
effective HSP length: 104
effective length of query: 271
effective length of database: 14,309,454
effective search space: 3877862034
effective search space used: 3877862034
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 63 (28.9 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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