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Search of human proteins with 42794779
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|42794779 myosin 18A isoform b [Homo sapiens]
(2039 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|42794779 myosin 18A isoform b [Homo sapiens] 3969 0.0
gi|28416946 myosin 18A isoform a [Homo sapiens] 3959 0.0
gi|51317366 myosin XVIIIB [Homo sapiens] 1385 0.0
gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Ho... 599 e-171
gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Ho... 598 e-170
gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Ho... 597 e-170
gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Ho... 597 e-170
gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens] 588 e-167
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 581 e-165
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 531 e-150
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 528 e-149
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 527 e-149
gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo s... 515 e-145
gi|156104908 myosin heavy chain 6 [Homo sapiens] 513 e-145
gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo... 511 e-144
gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo... 507 e-143
gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo... 506 e-143
gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo... 506 e-143
gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta ... 506 e-142
gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [... 502 e-141
gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [H... 502 e-141
gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo ... 501 e-141
gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens] 494 e-139
gi|153945715 myosin VC [Homo sapiens] 302 3e-81
gi|215982794 myosin VA isoform 2 [Homo sapiens] 295 2e-79
gi|215982791 myosin VA isoform 1 [Homo sapiens] 294 5e-79
gi|122937345 myosin VB [Homo sapiens] 286 1e-76
gi|154354979 myosin X [Homo sapiens] 228 4e-59
gi|189083802 myosin VIIA isoform 2 [Homo sapiens] 225 3e-58
gi|189083800 myosin VIIA isoform 3 [Homo sapiens] 225 3e-58
>gi|42794779 myosin 18A isoform b [Homo sapiens]
Length = 2039
Score = 3969 bits (10294), Expect = 0.0
Identities = 2039/2039 (100%), Positives = 2039/2039 (100%)
Query: 1 MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSLRRGFFNLNRSSKRESKTRL 60
MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSLRRGFFNLNRSSKRESKTRL
Sbjct: 1 MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSLRRGFFNLNRSSKRESKTRL 60
Query: 61 EISNPIPIKVASGSDLHLTDIDSDSNRGSVILDSGHLSTASSSDDLKGEEGSFRGSVLQR 120
EISNPIPIKVASGSDLHLTDIDSDSNRGSVILDSGHLSTASSSDDLKGEEGSFRGSVLQR
Sbjct: 61 EISNPIPIKVASGSDLHLTDIDSDSNRGSVILDSGHLSTASSSDDLKGEEGSFRGSVLQR 120
Query: 121 AAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHP 180
AAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHP
Sbjct: 121 AAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHP 180
Query: 181 GPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTM 240
GPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTM
Sbjct: 181 GPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTM 240
Query: 241 LDRGPEGQACRRVVHFAEPGAGTKDLALGLVPGDRLVEINGHNVESKSRDEIVEMIRQSG 300
LDRGPEGQACRRVVHFAEPGAGTKDLALGLVPGDRLVEINGHNVESKSRDEIVEMIRQSG
Sbjct: 241 LDRGPEGQACRRVVHFAEPGAGTKDLALGLVPGDRLVEINGHNVESKSRDEIVEMIRQSG 300
Query: 301 DSVRLKVQPIPELSELSRSWLRSGEGPRREPSDAKTEEQIAAEEAWNETEKVWLVHRDGF 360
DSVRLKVQPIPELSELSRSWLRSGEGPRREPSDAKTEEQIAAEEAWNETEKVWLVHRDGF
Sbjct: 301 DSVRLKVQPIPELSELSRSWLRSGEGPRREPSDAKTEEQIAAEEAWNETEKVWLVHRDGF 360
Query: 361 SLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESS 420
SLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESS
Sbjct: 361 SLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESS 420
Query: 421 VLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQT 480
VLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQT
Sbjct: 421 VLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQT 480
Query: 481 AYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLE 540
AYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLE
Sbjct: 481 AYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLE 540
Query: 541 AFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYY 600
AFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYY
Sbjct: 541 AFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYY 600
Query: 601 LLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQK 660
LLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQK
Sbjct: 601 LLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQK 660
Query: 661 ACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKG 720
ACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKG
Sbjct: 661 ACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKG 720
Query: 721 GTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQH 780
GTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQH
Sbjct: 721 GTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQH 780
Query: 781 SLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENI 840
SLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENI
Sbjct: 781 SLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENI 840
Query: 841 ELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLER 900
ELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLER
Sbjct: 841 ELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLER 900
Query: 901 LFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPR 960
LFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPR
Sbjct: 901 LFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPR 960
Query: 961 LLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS 1020
LLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS
Sbjct: 961 LLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS 1020
Query: 1021 LCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC 1080
LCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC
Sbjct: 1021 LCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC 1080
Query: 1081 EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNY 1140
EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNY
Sbjct: 1081 EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNY 1140
Query: 1141 IVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACR 1200
IVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACR
Sbjct: 1141 IVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACR 1200
Query: 1201 GYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD 1260
GYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD
Sbjct: 1201 GYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD 1260
Query: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL 1320
EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL
Sbjct: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL 1320
Query: 1321 RAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVR 1380
RAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVR
Sbjct: 1321 RAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVR 1380
Query: 1381 EVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ 1440
EVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ
Sbjct: 1381 EVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ 1440
Query: 1441 DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ 1500
DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ
Sbjct: 1441 DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ 1500
Query: 1501 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDE 1560
QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDE
Sbjct: 1501 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDE 1560
Query: 1561 QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE 1620
QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE
Sbjct: 1561 QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE 1620
Query: 1621 DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP 1680
DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP
Sbjct: 1621 DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP 1680
Query: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740
SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE
Sbjct: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740
Query: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800
KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL
Sbjct: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800
Query: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860
QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD
Sbjct: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860
Query: 1861 QRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQA 1920
QRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQA
Sbjct: 1861 QRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQA 1920
Query: 1921 DLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSK 1980
DLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSK
Sbjct: 1921 DLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSK 1980
Query: 1981 AASDDGSLKSSSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYLSDSDTEAKLTETNA 2039
AASDDGSLKSSSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYLSDSDTEAKLTETNA
Sbjct: 1981 AASDDGSLKSSSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYLSDSDTEAKLTETNA 2039
>gi|28416946 myosin 18A isoform a [Homo sapiens]
Length = 2054
Score = 3959 bits (10268), Expect = 0.0
Identities = 2039/2054 (99%), Positives = 2039/2054 (99%), Gaps = 15/2054 (0%)
Query: 1 MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSLRRGFFNLNRSSKRESKTRL 60
MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSLRRGFFNLNRSSKRESKTRL
Sbjct: 1 MFNLMKKDKDKDGGRKEKKEKKEKKERMSAAELRSLEEMSLRRGFFNLNRSSKRESKTRL 60
Query: 61 EISNPIPIKVASGSDLHLTDIDSDSNRGSVILDSGHLSTASSSDDLKGEEGSFRGSVLQR 120
EISNPIPIKVASGSDLHLTDIDSDSNRGSVILDSGHLSTASSSDDLKGEEGSFRGSVLQR
Sbjct: 61 EISNPIPIKVASGSDLHLTDIDSDSNRGSVILDSGHLSTASSSDDLKGEEGSFRGSVLQR 120
Query: 121 AAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHP 180
AAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHP
Sbjct: 121 AAKFGSLAKQNSQMIVKRFSFSQRSRDESASETSTPSEHSAAPSPQVEVRTLEGQLVQHP 180
Query: 181 GPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTM 240
GPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTM
Sbjct: 181 GPGIPRPGHRSRAPELVTKKFPVDLRLPPVVPLPPPTLRELELQRRPTGDFGFSLRRTTM 240
Query: 241 LDRGPEGQACRRVVHFAEPGAGTKDLALGLVPGDRLVEINGHNVESKSRDEIVEMIRQSG 300
LDRGPEGQACRRVVHFAEPGAGTKDLALGLVPGDRLVEINGHNVESKSRDEIVEMIRQSG
Sbjct: 241 LDRGPEGQACRRVVHFAEPGAGTKDLALGLVPGDRLVEINGHNVESKSRDEIVEMIRQSG 300
Query: 301 DSVRLKVQPIPELSELSRSWLRSGEGPRREPSDAKTEEQIAAEEAWNETEKVWLVHRDGF 360
DSVRLKVQPIPELSELSRSWLRSGEGPRREPSDAKTEEQIAAEEAWNETEKVWLVHRDGF
Sbjct: 301 DSVRLKVQPIPELSELSRSWLRSGEGPRREPSDAKTEEQIAAEEAWNETEKVWLVHRDGF 360
Query: 361 SLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESS 420
SLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESS
Sbjct: 361 SLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESS 420
Query: 421 VLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQT 480
VLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQT
Sbjct: 421 VLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQT 480
Query: 481 AYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLE 540
AYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLE
Sbjct: 481 AYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLE 540
Query: 541 AFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYY 600
AFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYY
Sbjct: 541 AFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYY 600
Query: 601 LLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQK 660
LLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQK
Sbjct: 601 LLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQK 660
Query: 661 ACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKG 720
ACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKG
Sbjct: 661 ACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKG 720
Query: 721 GTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQH 780
GTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQH
Sbjct: 721 GTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQH 780
Query: 781 SLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENI 840
SLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENI
Sbjct: 781 SLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENI 840
Query: 841 ELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLER 900
ELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLER
Sbjct: 841 ELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLER 900
Query: 901 LFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPR 960
LFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPR
Sbjct: 901 LFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPR 960
Query: 961 LLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS 1020
LLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS
Sbjct: 961 LLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS 1020
Query: 1021 LCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC 1080
LCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC
Sbjct: 1021 LCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC 1080
Query: 1081 EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNY 1140
EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNY
Sbjct: 1081 EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNY 1140
Query: 1141 IVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACR 1200
IVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACR
Sbjct: 1141 IVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACR 1200
Query: 1201 GYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD 1260
GYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD
Sbjct: 1201 GYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD 1260
Query: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL 1320
EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL
Sbjct: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL 1320
Query: 1321 RAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVR 1380
RAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVR
Sbjct: 1321 RAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVR 1380
Query: 1381 EVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ 1440
EVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ
Sbjct: 1381 EVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ 1440
Query: 1441 DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ 1500
DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ
Sbjct: 1441 DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ 1500
Query: 1501 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDE 1560
QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDE
Sbjct: 1501 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDE 1560
Query: 1561 QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE 1620
QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE
Sbjct: 1561 QAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYE 1620
Query: 1621 DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP 1680
DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP
Sbjct: 1621 DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP 1680
Query: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740
SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE
Sbjct: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740
Query: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800
KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL
Sbjct: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800
Query: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860
QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD
Sbjct: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860
Query: 1861 QRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQA 1920
QRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQA
Sbjct: 1861 QRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQA 1920
Query: 1921 DLKLAFKRIGDLQAAIEDEMESDENEDLINS---------------EGDSDVDSELEDRV 1965
DLKLAFKRIGDLQAAIEDEMESDENEDLINS EGDSDVDSELEDRV
Sbjct: 1921 DLKLAFKRIGDLQAAIEDEMESDENEDLINSLQDMVTKYQKRKNKLEGDSDVDSELEDRV 1980
Query: 1966 DGVKSWLSKNKGPSKAASDDGSLKSSSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYL 2025
DGVKSWLSKNKGPSKAASDDGSLKSSSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYL
Sbjct: 1981 DGVKSWLSKNKGPSKAASDDGSLKSSSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYL 2040
Query: 2026 SDSDTEAKLTETNA 2039
SDSDTEAKLTETNA
Sbjct: 2041 SDSDTEAKLTETNA 2054
>gi|51317366 myosin XVIIIB [Homo sapiens]
Length = 2567
Score = 1385 bits (3584), Expect = 0.0
Identities = 756/1671 (45%), Positives = 1131/1671 (67%), Gaps = 44/1671 (2%)
Query: 322 RSGEGPRREPSDAKTEEQIAA-EEAWNETEKVWLVHRDGFSLASQLKSEE--LNLPEGKV 378
+ G P+ E ++ + A E+ W E EKVWL +DGF+LA+ LK +E +LP G+V
Sbjct: 485 QDGPAPQEEGKGGQSRDSDQAPEDRWYEAEKVWLAQKDGFTLATVLKPDEGTADLPAGRV 544
Query: 379 RVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYA 438
R+ +D D I +VDE+ V +AN P D++EDLASL+ +NESSVL+TL QRY A LLHT
Sbjct: 545 RLWIDADKTITEVDEEHVHRANPPELDQVEDLASLISVNESSVLNTLLQRYKAQLLHTCT 604
Query: 439 GPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLG 498
GP L+VL PRG + KV KG RR+ + HI ++AQ AY A+L R+DQSI+ LG
Sbjct: 605 GPDLIVLQPRGPSVPSAGKVP---KG-RRDGLPAHIGSMAQRAYWALLNQRRDQSIVALG 660
Query: 499 SSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYTLLEAFGNSPTIINGNATRFSQ 558
SG+GKTT C+ ++++L +AG +V SVEK +A +T+L AFG+ + +ATRFS
Sbjct: 661 WSGAGKTTCCEQVLEHLVGMAGSVDGRV-SVEKIRATFTVLRAFGSVSMAHSRSATRFSM 719
Query: 559 ILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHL 618
++SLDF+ G++ +A +QTMLLEK RVAR+P E+ F VF +LA D LRTEL+L+ +
Sbjct: 720 VMSLDFNATGRITAAQLQTMLLEKSRVARQPEGESNFLVFSQMLAGLDLDLRTELNLHQM 779
Query: 619 AENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGAT 678
A+++ FG+ +KPE+KQKAA F++LQ AM++LGIS EQ+A W +LAAIYHLGAAGA
Sbjct: 780 ADSSSFGMGVWSKPEDKQKAAAAFAQLQGAMEMLGISESEQRAVWRVLAAIYHLGAAGAC 839
Query: 679 KEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGL 738
K GRKQF R EWA AA LGC EEL++A FKH H +Q+ T GP GL
Sbjct: 840 K----VGRKQFMRFEWANYAAEALGCEYEELNTATFKH-HLRQIIQQMTF---GPSRWGL 891
Query: 739 GD---GTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQN 795
D +G K++ ++C+EGMA+GLY ELF +VSL+NR+ S S+ S+M+VD+PGFQN
Sbjct: 892 EDEETSSGLKMTGVDCVEGMASGLYQELFAAVVSLINRSFSSHHLSMASIMVVDSPGFQN 951
Query: 796 PEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSV 855
P G R A+FEELCHNY +RLQ LF++RTFV L+RY+EE + + FD +P +V
Sbjct: 952 PRHQGKDRAATFEELCHNYAHERLQLLFYQRTFVSTLQRYQEEGVPVQFDLPDPSPGTTV 1011
Query: 856 AAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQ 915
A VDQ Q + + +ARGL W+L+EE V G+S+ +LERL + + + +G
Sbjct: 1012 AVVDQNPSQVRLPAGGGAQDARGLFWVLDEEVHVEGSSDSVVLERLCAAFEKKGAGTEGS 1071
Query: 916 SPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFL 975
S L +P + H G + V Y++TGWL+ K N + +AP++L S+++ + +LF
Sbjct: 1072 SALRTCEQPLQCEIFHQLGWDPVRYDLTGWLHRAKPNLSALDAPQVLHQSKREELRSLFQ 1131
Query: 976 GRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDT 1035
RA V ++AGLEG SQ AL+R+ +R+TF + +AAV++K+ C Q+KLQ+DAL
Sbjct: 1132 ARAKLPPVCR-AVAGLEGTSQQALQRSRMVRRTFASSLAAVRRKAPCSQIKLQMDALTSM 1190
Query: 1036 IKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQ 1095
IK+S+LHF+HC +P E RS D P G L LD+P LR Q
Sbjct: 1191 IKRSRLHFIHCLVPNP---VVESRSGQESPPPPQPGRDKPGA----GGPLALDIPALRVQ 1243
Query: 1096 LRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLEC 1155
L G +L+A+R++R GY DHM + FRR+F VL L KK +DER+AVEELLE
Sbjct: 1244 LAGFHILEALRLHRTGYADHMGLTRFRRQFQVLDAPLLKKLMSTSEGIDERKAVEELLET 1303
Query: 1156 LDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQD 1215
LDLEK + +G S+VF +AG ++RLE+QR++ S+++ LFQAAC+G+L+RQ FKK KI+
Sbjct: 1304 LDLEKKAVAVGHSQVFLKAGVISRLEKQREKLVSQSIVLFQAACKGFLSRQEFKKLKIRR 1363
Query: 1216 LAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEK 1275
LA +C+QKN+ VKDWPWW+L +++PL+ + EQ+R K+EE+ LR KLEK+EK
Sbjct: 1364 LAAQCIQKNVAVFLAVKDWPWWQLLGSLQPLLSATIGTEQLRAKEEELTTLRRKLEKSEK 1423
Query: 1276 ERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDA 1335
RNELR N+D LES+I++LTS+L DER G+ A Q+L++E AERL+A +E++EL+++++
Sbjct: 1424 LRNELRQNTDLLESKIADLTSDLADERFKGDVACQVLESERAERLQAFREVQELKSKHEQ 1483
Query: 1336 LKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGG--EWRLKYERAVREVDFTKKRLQQEF 1393
++K++ + ++ EA+ + ++N +++ + GG EW+++++ A E +F +KRLQQ
Sbjct: 1484 VQKKLGDVNKQLEEAQ--QKIQLN-DLERNPTGGADEWQMRFDCAQMENEFLRKRLQQ-C 1539
Query: 1394 EDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRN 1453
E++L+ E +++LE++LG+LQ+ + +++ QLK+KC LT +L+DT + LE QQ RN
Sbjct: 1540 EERLDSELTARKELEQKLGELQSAYDGAKKMAHQLKRKCHHLTCDLEDTCVLLENQQSRN 1599
Query: 1454 HELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFT 1513
HELEKKQ++FD +L+QA E+ EK REK+ +E + E L+QQL++K+ + +
Sbjct: 1600 HELEKKQKKFDLQLAQALGESVFEKGLREKVTQENTSVRWELGQLQQQLKQKEQEASQLK 1659
Query: 1514 QKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKL 1573
Q+V L+ +++ S E +A +K++L LE+ +Q++ +Q TI+ LEQ +
Sbjct: 1660 QQVEMLQDHKRELLGSPSLGENCVAGLKERLWKLESSALEQQKIQSQQENTIKQLEQLRQ 1719
Query: 1574 RLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELE 1633
R E+E+ERM+Q H K+ E ++EE+E+ RQSCQK+L Q+E+QLE+EYE+KQ VL EK++LE
Sbjct: 1720 RFELEIERMKQMHQKDREDQEEELEDVRQSCQKRLHQLEMQLEQEYEEKQMVLHEKQDLE 1779
Query: 1634 GKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKN--SAPSKREIAQLKNQ 1691
G + TL DQ+ RDF+ EKRLR+DL+RT ALL+D QL+L +++ ++ SK E+ ++ +Q
Sbjct: 1780 GLIGTLCDQIGHRDFDVEKRLRRDLRRTHALLSDVQLLLGTMEDGKTSVSKEELEKVHSQ 1839
Query: 1692 LEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEED 1751
LE+SE C A+K +K + ++E +H +++++ + K+ ++EQL RLQ EK ++ R++ED
Sbjct: 1840 LEQSEAKCEEALKTQKVLTADLESMHSELENMTRNKSLVDEQLYRLQFEKADLLKRIDED 1899
Query: 1752 QEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSM 1811
Q+D+NELM+KHK +AQ++ D+ QI +LQ QLEEA KEK +LQE+LQ Q ++E+LEQS
Sbjct: 1900 QDDLNELMQKHKDLIAQSAADIGQIQELQLQLEEAKKEKHKLQEQLQVAQMRIEYLEQST 1959
Query: 1812 VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKE 1871
VD+++VSRQEA I +LE + EF++ Q+KR E L RL++++ K+ EE Q +E++++E
Sbjct: 1960 VDRAIVSRQEAVICDLENKTEFQKVQIKRFEVLVIRLRDSLIKMGEELSQAATSESQQRE 2019
Query: 1872 QNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGD 1931
++ QR+L + K +M EL ++EAEASR+ ELE +E L A Q+LQ DL+ + +RI D
Sbjct: 2020 SSQYYQRRLEELKADMEELVQREAEASRRCMELEKYVEELAAVRQTLQTDLETSIRRIAD 2079
Query: 1932 LQAAIEDEMESDENEDLI------NSEGDSDVD--SELEDRVDG-VKSWLS 1973
LQAA+E+ SD + + + S G ++D S L + +G ++SWLS
Sbjct: 2080 LQAALEEVASSDSDTESVQTAVDCGSSGRKEMDNVSILSSQPEGSLQSWLS 2130
>gi|13124879 smooth muscle myosin heavy chain 11 isoform SM1A [Homo
sapiens]
Length = 1972
Score = 599 bits (1545), Expect = e-171
Identities = 497/1750 (28%), Positives = 865/1750 (49%), Gaps = 272/1750 (15%)
Query: 342 AEEAWNETEKVWLV-HRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKAN 400
A+ W VW+ + GF AS +K E+ + +V V+L +G + V +DD++K N
Sbjct: 26 AQADWAAKRLVWVPSEKQGFEAAS-IKEEKGD----EVVVELVENGKKVTVGKDDIQKMN 80
Query: 401 APSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMH 460
P ++ED+A L LNE+SVLH LR+RY + L++TY+G +V+ P +YSEK++
Sbjct: 81 PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140
Query: 461 MFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAG 520
M+KG +R +M PHIYA+A TAYR+ML R+DQSI+ G SG+GKT + + ++QYLA +A
Sbjct: 141 MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200
Query: 521 I-SGNKVFSVE---KWQALYT--LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASAS 574
G K S+ + Q L +LEAFGN+ T+ N N++RF + + ++FD G + A+
Sbjct: 201 SHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260
Query: 575 IQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHL----NHLAENNVFGIVPLA 630
I+T LLEK R R+ E TF++FYY++A +R++L L N+ +N F +P A
Sbjct: 261 IETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAA 320
Query: 631 KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690
+ +E F + AM ++G S +EQ + +++++ LG KE +
Sbjct: 321 QDDE------MFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKER-NTDQASMP 373
Query: 691 RHEWAQKAAYLLGCSLEELSSAIFKHQHKGG--TLQRSTSFRQGPEESGLGDGTGPKLSA 748
+ AQK +L+G ++ + + +I + K G +Q++ + Q A
Sbjct: 374 DNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQ----------------A 417
Query: 749 LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807
+E +A Y LF +++ VN+AL + S + I+D GF+ E SF
Sbjct: 418 DFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVN------SF 471
Query: 808 EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867
E+LC NYT ++LQ+LF+ F+ E E Y+ E IE F D Q +
Sbjct: 472 EQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFG------------LDLQPCI 519
Query: 868 RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927
+ R + G+L LL+EE P A++ + +E+L + G K Q P K
Sbjct: 520 ELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHP---KFQKPKQLKDKTEFS 576
Query: 928 LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGS 987
++ H V+YN + WL +P N LL S K +++L+
Sbjct: 577 II---HYAGKVDYNASAWLT-KNMDPLNDNVTSLLNASSDKFVADLWKD--------VDR 624
Query: 988 IAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCF 1047
I GL+ +++ S KT GM +++ K Q+ L+ T++ + +FV C
Sbjct: 625 IVGLDQMAKMTESSLPSASKT-KKGMF----RTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679
Query: 1048 LPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRM 1107
+P E +G+ LD L+ QLR + +L+ +R+
Sbjct: 680 IPNHEKRSGK-----------------------------LDAFLVLEQLRCNGVLEGIRI 710
Query: 1108 YRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGL 1167
RQG+P+ +VF EFR+R+++LA + K +D ++A +++ L+L+ + +G
Sbjct: 711 CRQGFPNRIVFQEFRQRYEILAANAIPKG-----FMDGKQACILMIKALELDPNLYRIGQ 765
Query: 1168 SRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKK 1227
S++FFR G LA LEE+RD + + + FQA CRGYLAR+ F KR+ Q A++ +Q+N
Sbjct: 766 SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 825
Query: 1228 NKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRL 1287
+++W WW+LFT V+PL++V EE+++ K++E+Q+ + + +KAE E EL
Sbjct: 826 YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKEL------- 878
Query: 1288 ESRISELTSE--LTDERNTGESASQLLDAETAERLRAEK-EMKELQTQYDALKKQMEVME 1344
E + S+LT E L E+ E+ E RL A+K E++E+ + +A ++ E
Sbjct: 879 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 938
Query: 1345 MEVMEARLIRAAE---INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEF---EDKLE 1398
++ R A + + ++++++A + +L+ E+ E K+L+ E +D+
Sbjct: 939 QQLQAERKKMAQQMLDLEEQLEEEEAARQ-KLQLEKVTAEAKI--KKLEDEILVMDDQNN 995
Query: 1399 VEQQNKRQLERRLGDLQ---ADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE 1455
+ ++ LE R+ DL A+ EE + L +LK K + + +EL+ + L+ ++ E
Sbjct: 996 KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE---VRLKKEEKSRQE 1052
Query: 1456 LEKKQRRFDSELSQAHEE-----AQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIA 1510
LEK +R+ + + S HE+ AQ +L+ + ++E+++ A A L ++ +K+ +
Sbjct: 1053 LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA-RLDDEIAQKNNAL- 1110
Query: 1511 GFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDL----EAKVKDQEEELD------- 1559
+K+ LE + D+ + A+ K +KQ RDL EA + E+ LD
Sbjct: 1111 ---KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
Query: 1560 -----EQAGTI--QMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQME 1612
EQ T+ + L++ E +++ MRQ H++ +E E++E+ +++ + L + +
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA-KANLDKNK 1226
Query: 1613 VQLEEEYED-----------KQKVLREKRELEGKL--------------ATLSDQVNRRD 1647
LE+E D KQ+V +K++LE ++ A L+D+V++
Sbjct: 1227 QTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286
Query: 1648 FESEK-------------RLRKDLKRTKALLADAQLML---------------------- 1672
E E +L KD+ + L D Q +L
Sbjct: 1287 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1346
Query: 1673 ---DHLKNSAPSKR-----------EIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHL 1718
D L +K+ +++ K +L++ T A + +K + EIE+L
Sbjct: 1347 SLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ 1406
Query: 1719 QIDDIAKAKTALEEQLSRLQRE----------KNEIQNRLEEDQEDMNELMKKHK----- 1763
Q ++ A A LE+ +RLQ+E + ++ + LE+ Q ++L+ + K
Sbjct: 1407 QYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSK 1466
Query: 1764 ------AAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSL- 1816
A A+A + L LEEA + K+EL+ + L++++E L S D
Sbjct: 1467 YADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKN 1526
Query: 1817 VSRQEAKIRELETRLEFERTQVKRLESLAS-------RLKENMEKLTEERDQRIAAENRE 1869
V E R LET++E +TQ++ LE RL+ NM+ L + ++ + A + +
Sbjct: 1527 VHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQ 1586
Query: 1870 KEQNKR-LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKR 1928
E+ +R LQRQL + + E+ + ++ A A+ K +LE DL+ LE S + A K+
Sbjct: 1587 NEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQ 1646
Query: 1929 IGDLQAAIED 1938
+ LQA ++D
Sbjct: 1647 LRKLQAQMKD 1656
Score = 231 bits (589), Expect = 5e-60
Identities = 189/738 (25%), Positives = 372/738 (50%), Gaps = 61/738 (8%)
Query: 1224 NIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE-EIQQLRSKLEKAEKERNELRL 1282
N+ KNK + L +R L + + E + K E ++Q+L+SK E+ R EL
Sbjct: 1221 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELND 1280
Query: 1283 NSDRLESRISELTSELTDERNTG--------------ESASQLLDAETAERLRAEKEMKE 1328
+L++ + +T L + + +LL ET ++L ++++
Sbjct: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1340
Query: 1329 LQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKR 1388
L+ + ++L+ Q++ EME + + +N ++ D +KK+
Sbjct: 1341 LEEERNSLQDQLDE-EMEAKQNLERHISTLNIQLSD--------------------SKKK 1379
Query: 1389 LQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEG 1448
LQ +F +E ++ K++ ++ + +L EE A +L+K RL EL D + L+
Sbjct: 1380 LQ-DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438
Query: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD 1508
Q+ LEKKQR+FD L++ + + +R++ + E +A SL + LEE
Sbjct: 1439 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1498
Query: 1509 IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
+ L+AE++D+ S + ++ +++K R LE ++++ + +L+E +Q
Sbjct: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
Query: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
E AKLRLE+ M+ ++ +++++RDE+ EE R+ Q++L + E +LE+E + +
Sbjct: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618
Query: 1629 KRELEGKLATL---SDQVNRRDFESEKRLRK---DLKRTKALLADAQLMLDHLKNSA-PS 1681
K++LEG L L +D + E+ K+LRK +K + L DA+ D + +A +
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678
Query: 1682 KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1741
+++ L+ L + + AAA +ARK ++E E+L ++ + AL+++ RL+
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738
Query: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQ 1801
+++ LEE+Q +M + + + A QA + ++ ++ ++ +Q+L+ + + L+
Sbjct: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1798
Query: 1802 SQVEFLEQSMVD--KSLVSRQEAKIRELETRLEFE-RTQVKRLESLASRLKENMEKLTEE 1858
S++ +E ++ KS ++ EAKI +LE ++E E R + +SL + K+ E L +
Sbjct: 1799 SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQV 1858
Query: 1859 RDQRIAAENREKEQN------KRLQRQLRDTKEEMGELARKEAEASRKKHELEMD--LES 1910
D+R AE +++ K+L+RQL + +EE + A+R+K + E+D ES
Sbjct: 1859 EDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE-----SQRINANRRKLQRELDEATES 1913
Query: 1911 LEAANQSLQADLKLAFKR 1928
EA + + A LK +R
Sbjct: 1914 NEAMGREVNA-LKSKLRR 1930
Score = 173 bits (438), Expect = 2e-42
Identities = 185/813 (22%), Positives = 352/813 (43%), Gaps = 137/813 (16%)
Query: 1254 EQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL-- 1311
EQI + +I +L+ +L K E+E L+ RL+ I++ + L R S L
Sbjct: 1069 EQIADLQAQIAELKMQLAKKEEE---LQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125
Query: 1312 -LDAETAERLRAEKEMKELQTQYDALKKQME------VMEMEVMEARLIRAAEINGEVDD 1364
LD+E A R +AEK+ ++L + +ALK ++E + E+ R + +D+
Sbjct: 1126 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185
Query: 1365 DDAGGE-----WRLKYERAVRE--------------VDFTKKRLQQEFED---------- 1395
+ E R K+ +AV E +D K+ L++E D
Sbjct: 1186 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1245
Query: 1396 -KLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRL------------------- 1435
K EVE + K++LE ++ +LQ+ + +RA +L K +L
Sbjct: 1246 AKQEVEHK-KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI 1304
Query: 1436 ---------TAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQR 1486
+++LQDT+ L+ + + + K R+ + E + ++ E ++ L+R
Sbjct: 1305 KLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLER 1364
Query: 1487 EKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRD 1546
L + K++L++ + + + E+++++ Q + A+ K++K
Sbjct: 1365 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1424
Query: 1547 LEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQK 1606
L+ ++ D +LD Q + LE+ + + + + + SK + RD EAR+ K
Sbjct: 1425 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1484
Query: 1607 KLKQMEVQLEEEYEDKQKVLREKRELEGKLATL---SDQVNRRDFESEKRLR-------- 1655
L LEE E K+++ R + L+ ++ L D V + E EK R
Sbjct: 1485 ALSLARA-LEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE 1543
Query: 1656 -----KDLKRTKALLADAQLMLD--------------------HLKNSAPSKREIAQLKN 1690
++L+ DA+L L+ + + +R++ + +
Sbjct: 1544 MKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYET 1603
Query: 1691 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1750
+LE+ A A A+K +E +++DL LQ D K + +QL +LQ + + Q LE+
Sbjct: 1604 ELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1663
Query: 1751 DQEDMNELM---KKHKAAVAQASRDLAQINDLQAQLEEANK----EKQELQEKLQALQSQ 1803
+ +E+ K+++ DL Q+ + A E A K EK+EL E+L + S
Sbjct: 1664 ARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG 1723
Query: 1804 VEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQR 1862
L+ R EA+I +LE LE E+ ++ + + + E+L+ E +R
Sbjct: 1724 RNALQDEK------RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1777
Query: 1863 IAAENRE--KEQNKRLQRQLRDTKEEM---------GELARKEAEASRKKHELEMDLESL 1911
A+ E ++Q +R ++LR EM +A EA+ ++ + ++E +
Sbjct: 1778 STAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREK 1837
Query: 1912 EAANQSLQADLKLAFKRIGDLQAAIEDEMESDE 1944
+AA +SL K K++ ++ +EDE + E
Sbjct: 1838 QAATKSL----KQKDKKLKEILLQVEDERKMAE 1866
>gi|13124875 smooth muscle myosin heavy chain 11 isoform SM2A [Homo
sapiens]
Length = 1938
Score = 598 bits (1543), Expect = e-170
Identities = 462/1684 (27%), Positives = 838/1684 (49%), Gaps = 187/1684 (11%)
Query: 342 AEEAWNETEKVWLV-HRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKAN 400
A+ W VW+ + GF AS +K E+ + +V V+L +G + V +DD++K N
Sbjct: 26 AQADWAAKRLVWVPSEKQGFEAAS-IKEEKGD----EVVVELVENGKKVTVGKDDIQKMN 80
Query: 401 APSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMH 460
P ++ED+A L LNE+SVLH LR+RY + L++TY+G +V+ P +YSEK++
Sbjct: 81 PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140
Query: 461 MFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAG 520
M+KG +R +M PHIYA+A TAYR+ML R+DQSI+ G SG+GKT + + ++QYLA +A
Sbjct: 141 MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200
Query: 521 I-SGNKVFSV-----EKWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASAS 574
G K S+ ++ +LEAFGN+ T+ N N++RF + + ++FD G + A+
Sbjct: 201 SHKGKKDTSITGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGAN 260
Query: 575 IQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHL----NHLAENNVFGIVPLA 630
I+T LLEK R R+ E TF++FYY++A +R++L L N+ +N F +P A
Sbjct: 261 IETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNGFVPIPAA 320
Query: 631 KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690
+ +E F + AM ++G S +EQ + +++++ LG KE +
Sbjct: 321 QDDE------MFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKE-RNTDQASMP 373
Query: 691 RHEWAQKAAYLLGCSLEELSSAIFKHQHKGG--TLQRSTSFRQGPEESGLGDGTGPKLSA 748
+ AQK +L+G ++ + + +I + K G +Q++ + K A
Sbjct: 374 DNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT----------------KEQA 417
Query: 749 LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807
+E +A Y LF +++ VN+AL + S + I+D GF+ E SF
Sbjct: 418 DFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVN------SF 471
Query: 808 EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867
E+LC NYT ++LQ+LF+ F+ E E Y+ E IE F D Q +
Sbjct: 472 EQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF------------GLDLQPCI 519
Query: 868 RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927
+ R + G+L LL+EE P A++ + +E+L + G K Q P K
Sbjct: 520 ELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG---SHPKFQKPKQLKDKTEFS 576
Query: 928 LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGS 987
++ H V+YN + WL +P N LL S K +++L+
Sbjct: 577 II---HYAGKVDYNASAWLT-KNMDPLNDNVTSLLNASSDKFVADLWKD--------VDR 624
Query: 988 IAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCF 1047
I GL+ +++ S KT GM +++ K Q+ L+ T++ + +FV C
Sbjct: 625 IVGLDQMAKMTESSLPSASKT-KKGMF----RTVGQLYKEQLGKLMTTLRNTTPNFVRCI 679
Query: 1048 LPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRM 1107
+P E +G +LD L+ QLR + +L+ +R+
Sbjct: 680 IPNHEKRSG-----------------------------KLDAFLVLEQLRCNGVLEGIRI 710
Query: 1108 YRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGL 1167
RQG+P+ +VF EFR+R+++LA + K +D ++A +++ L+L+ + +G
Sbjct: 711 CRQGFPNRIVFQEFRQRYEILAANAIPKG-----FMDGKQACILMIKALELDPNLYRIGQ 765
Query: 1168 SRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKK 1227
S++FFR G LA LEE+RD + + + FQA CRGYLAR+ F KR+ Q A++ +Q+N
Sbjct: 766 SKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKVIQRNCAA 825
Query: 1228 NKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRL 1287
+++W WW+LFT V+PL++V EE+++ K++E+Q+ + + +KAE E E L
Sbjct: 826 YLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKE-------L 878
Query: 1288 ESRISELTSE--LTDERNTGESASQLLDAETAERLRAEK-EMKELQTQYDALKKQMEVME 1344
E + S+LT E L E+ E+ E RL A+K E++E+ + +A ++ E
Sbjct: 879 EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARLEEEEDRG 938
Query: 1345 MEVMEARLIRA---AEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQE---FEDKLE 1398
++ R A ++ ++++++A + +L+ E+ E K+L+ E +D+
Sbjct: 939 QQLQAERKKMAQQMLDLEEQLEEEEAARQ-KLQLEKVTAEAKI--KKLEDEILVMDDQNN 995
Query: 1399 VEQQNKRQLERRLGDLQ---ADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE 1455
+ ++ LE R+ DL A+ EE + L +LK K + + +EL+ + L+ ++ E
Sbjct: 996 KLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE---VRLKKEEKSRQE 1052
Query: 1456 LEKKQRRFDSELSQAHE-----EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIA 1510
LEK +R+ + + S HE +AQ +L+ + ++E+++ A A L ++ +K+ +
Sbjct: 1053 LEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA-RLDDEIAQKNNAL- 1110
Query: 1511 GFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQ 1570
+K+ LE + D+ + A+ K +KQ RDL +++ + EL++ + ++
Sbjct: 1111 ---KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQE 1167
Query: 1571 AKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY-------EDKQ 1623
+ + E E+ +++ +E S + +V+E RQ + ++++ QLE+ ++KQ
Sbjct: 1168 LRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQ 1227
Query: 1624 KVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPS-K 1682
+ +E +L G+L L Q + +K+L ++ ++ +D + L + +
Sbjct: 1228 TLEKENADLAGELRVLG-QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQ 1286
Query: 1683 REIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKN 1742
E+ + L E+E K ++ +++D + + + K + +L +L+ E+N
Sbjct: 1287 NEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERN 1346
Query: 1743 EIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQS 1802
+Q++L+E+ E L + Q S ++ D + +E + K+ Q++++ L
Sbjct: 1347 SLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQ 1406
Query: 1803 QVEFLEQSMVDK--SLVSRQEAKIRELETRLEFERTQVKRLE-------SLASRLKENME 1853
Q E + + DK +R + ++ +L L+ +R V LE L + K
Sbjct: 1407 QYE-EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISS 1465
Query: 1854 KLTEERDQRIAAENREK---------------EQNKRLQRQLRDTKEEMGELARKEAEAS 1898
K +ERD R AE REK E + L+R + K EM +L + +
Sbjct: 1466 KYADERD-RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVG 1524
Query: 1899 RKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD 1958
+ HELE +LE + ++ L+ + +LQA + ++ + N + + + D+
Sbjct: 1525 KNVHELEKSKRALETQMEEMKTQLE---ELEDELQATEDAKLRLEVNMQALKGQFERDLQ 1581
Query: 1959 SELE 1962
+ E
Sbjct: 1582 ARDE 1585
Score = 231 bits (588), Expect = 7e-60
Identities = 187/730 (25%), Positives = 367/730 (50%), Gaps = 60/730 (8%)
Query: 1224 NIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE-EIQQLRSKLEKAEKERNELRL 1282
N+ KNK + L +R L + + E + K E ++Q+L+SK E+ R EL
Sbjct: 1221 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELND 1280
Query: 1283 NSDRLESRISELTSELTDERNTG--------------ESASQLLDAETAERLRAEKEMKE 1328
+L++ + +T L + + +LL ET ++L ++++
Sbjct: 1281 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1340
Query: 1329 LQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKR 1388
L+ + ++L+ Q++ EME + + +N ++ D +KK+
Sbjct: 1341 LEEERNSLQDQLDE-EMEAKQNLERHISTLNIQLSD--------------------SKKK 1379
Query: 1389 LQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEG 1448
LQ +F +E ++ K++ ++ + +L EE A +L+K RL EL D + L+
Sbjct: 1380 LQ-DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1438
Query: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD 1508
Q+ LEKKQR+FD L++ + + +R++ + E +A SL + LEE
Sbjct: 1439 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1498
Query: 1509 IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
+ L+AE++D+ S + ++ +++K R LE ++++ + +L+E +Q
Sbjct: 1499 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1558
Query: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
E AKLRLE+ M+ ++ +++++RDE+ EE R+ Q++L + E +LE+E + +
Sbjct: 1559 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1618
Query: 1629 KRELEGKLATL---SDQVNRRDFESEKRLRK---DLKRTKALLADAQLMLDHLKNSAPSK 1682
K++LEG L L +D + E+ K+LRK +K + L DA+ D + +A
Sbjct: 1619 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1678
Query: 1683 REIAQ-LKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1741
+ A+ L+ L + + AAA +ARK ++E E+L ++ + AL+++ RL+
Sbjct: 1679 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1738
Query: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQ 1801
+++ LEE+Q +M + + + A QA + ++ ++ ++ +Q+L+ + + L+
Sbjct: 1739 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1798
Query: 1802 SQVEFLEQSMVDK--SLVSRQEAKIRELETRLEFE-RTQVKRLESLASRLKENMEKLTEE 1858
S++ +E ++ K S ++ EAKI +LE ++E E R + +SL + K+ E L +
Sbjct: 1799 SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQV 1858
Query: 1859 RDQRIAAENREKEQNK------RLQRQLRDTKEEMGELARKEAEASRKKHELEMD--LES 1910
D+R AE +++ K +L+RQL + +EE + A+R+K + E+D ES
Sbjct: 1859 EDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE-----SQRINANRRKLQRELDEATES 1913
Query: 1911 LEAANQSLQA 1920
EA + + A
Sbjct: 1914 NEAMGREVNA 1923
Score = 179 bits (455), Expect = 2e-44
Identities = 197/856 (23%), Positives = 373/856 (43%), Gaps = 62/856 (7%)
Query: 1180 LEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKL 1239
LEEQ +E+ + L A KK + + L + + K + + + L
Sbjct: 955 LEEQLEEEEAARQKL---QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1011
Query: 1240 FTTVRPLIEVQLSEEQIRNKDEE-IQQLRSKLEKAEKERNEL-----RLNSDR------- 1286
T + E + +++NK E I +L +L+K EK R EL +L D
Sbjct: 1012 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQI 1071
Query: 1287 --LESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQM---- 1340
L+++I+EL +L + ++A LD E A++ A K+++EL+ L++ +
Sbjct: 1072 ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSER 1131
Query: 1341 ------EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE 1394
E + ++ E E+ +D E R K E+ EV KK L +E
Sbjct: 1132 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ---EVTVLKKALDEETR 1188
Query: 1395 DKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNH 1454
Q+ +++ + + +L E+ +RA L K Q L E D L
Sbjct: 1189 SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1248
Query: 1455 ELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQ 1514
E+E K+++ ++++ + + + R +L + L E S+ L E + +
Sbjct: 1249 EVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1308
Query: 1515 KVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLR 1574
V SL ++LQD ++ V +LR LE + +++LDE+ Q LE+
Sbjct: 1309 DVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIST 1368
Query: 1575 LEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEG 1634
L +++ ++ ++ S E +EE ++ QK+++ + Q EE+ K+ + K L+
Sbjct: 1369 LNIQLSDSKKK-LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ 1427
Query: 1635 KLATLS-DQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLE 1693
+L L D N+R S L K ++ LLA+ + ++ + +R+ A+ + + +
Sbjct: 1428 ELDDLVVDLDNQRQLVSN--LEKKQRKFDQLLAEEK----NISSKYADERDRAEAEAREK 1481
Query: 1694 ESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQE 1753
E++ A+ +A+E +E AK LE L+ E ++ + ++ +
Sbjct: 1482 ETK-----ALSLARALEEALE-----------AKEELERTNKMLKAEMEDLVSSKDDVGK 1525
Query: 1754 DMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVD 1813
+++EL K +A Q Q+ +L+ +L+ K L+ +QAL+ Q E Q+ +
Sbjct: 1526 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE 1585
Query: 1814 KSLVSRQEAK--IRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKE 1871
++ R++ + + E ET LE ER Q + +L+ +++ L + D I +
Sbjct: 1586 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1645
Query: 1872 QNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLA--FKRI 1929
Q ++LQ Q++D + E+ + E E E +SLEA LQ DL A ++
Sbjct: 1646 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1705
Query: 1930 GDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDDGSLK 1989
DL+ ++E+ + L D LE R+ ++ L + +G +A SD
Sbjct: 1706 ADLE---KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1762
Query: 1990 SSSPTSYWKSLAPDRS 2005
+ LA +RS
Sbjct: 1763 TQQAEQLSNELATERS 1778
Score = 173 bits (438), Expect = 2e-42
Identities = 185/813 (22%), Positives = 352/813 (43%), Gaps = 137/813 (16%)
Query: 1254 EQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL-- 1311
EQI + +I +L+ +L K E+E L+ RL+ I++ + L R S L
Sbjct: 1069 EQIADLQAQIAELKMQLAKKEEE---LQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1125
Query: 1312 -LDAETAERLRAEKEMKELQTQYDALKKQME------VMEMEVMEARLIRAAEINGEVDD 1364
LD+E A R +AEK+ ++L + +ALK ++E + E+ R + +D+
Sbjct: 1126 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1185
Query: 1365 DDAGGE-----WRLKYERAVRE--------------VDFTKKRLQQEFED---------- 1395
+ E R K+ +AV E +D K+ L++E D
Sbjct: 1186 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1245
Query: 1396 -KLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRL------------------- 1435
K EVE + K++LE ++ +LQ+ + +RA +L K +L
Sbjct: 1246 AKQEVEHK-KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI 1304
Query: 1436 ---------TAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQR 1486
+++LQDT+ L+ + + + K R+ + E + ++ E ++ L+R
Sbjct: 1305 KLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLER 1364
Query: 1487 EKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRD 1546
L + K++L++ + + + E+++++ Q + A+ K++K
Sbjct: 1365 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1424
Query: 1547 LEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQK 1606
L+ ++ D +LD Q + LE+ + + + + + SK + RD EAR+ K
Sbjct: 1425 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1484
Query: 1607 KLKQMEVQLEEEYEDKQKVLREKRELEGKLATL---SDQVNRRDFESEKRLR-------- 1655
L LEE E K+++ R + L+ ++ L D V + E EK R
Sbjct: 1485 ALSLARA-LEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE 1543
Query: 1656 -----KDLKRTKALLADAQLMLD--------------------HLKNSAPSKREIAQLKN 1690
++L+ DA+L L+ + + +R++ + +
Sbjct: 1544 MKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYET 1603
Query: 1691 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1750
+LE+ A A A+K +E +++DL LQ D K + +QL +LQ + + Q LE+
Sbjct: 1604 ELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1663
Query: 1751 DQEDMNELM---KKHKAAVAQASRDLAQINDLQAQLEEANK----EKQELQEKLQALQSQ 1803
+ +E+ K+++ DL Q+ + A E A K EK+EL E+L + S
Sbjct: 1664 ARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG 1723
Query: 1804 VEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQR 1862
L+ R EA+I +LE LE E+ ++ + + + E+L+ E +R
Sbjct: 1724 RNALQDEK------RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1777
Query: 1863 IAAENRE--KEQNKRLQRQLRDTKEEM---------GELARKEAEASRKKHELEMDLESL 1911
A+ E ++Q +R ++LR EM +A EA+ ++ + ++E +
Sbjct: 1778 STAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREK 1837
Query: 1912 EAANQSLQADLKLAFKRIGDLQAAIEDEMESDE 1944
+AA +SL K K++ ++ +EDE + E
Sbjct: 1838 QAATKSL----KQKDKKLKEILLQVEDERKMAE 1866
Score = 120 bits (301), Expect = 1e-26
Identities = 132/583 (22%), Positives = 263/583 (45%), Gaps = 60/583 (10%)
Query: 1174 AGTLARLEE--QRDEQTSRNLTL-FQAACRGYLARQHFKKRKIQDLAIRCV----QKNIK 1226
A T+ LEE +R ++ NLT ++ Y + K R Q+L V Q+ +
Sbjct: 1384 ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1443
Query: 1227 KNKGVKDWPWWKLFTTVRPLI-----EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELR 1281
N K + +L + + E +E + R K+ + L LE+A + + EL
Sbjct: 1444 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1503
Query: 1282 LNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQME 1341
+ L++ + +L S D G++ +L EK + L+TQ + +K Q+E
Sbjct: 1504 RTNKMLKAEMEDLVSSKDD---VGKNVHEL-----------EKSKRALETQMEEMKTQLE 1549
Query: 1342 VMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQ 1401
+E E+ +DA +L+ E ++ + K + +++ + + E +
Sbjct: 1550 ELEDELQAT--------------EDA----KLRLEVNMQAL---KGQFERDLQARDEQNE 1588
Query: 1402 QNKRQLERRLGDLQADSEES--QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKK 1459
+ +RQL+R+L + + + E+ QRAL KK +L +L+D +L + E K+
Sbjct: 1589 EKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLEGDLKDLELQADSAIKGREEAIKQ 1646
Query: 1460 QRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSL 1519
R+ +++ E + + R+++ +A SL+ L + D+A +
Sbjct: 1647 LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 1706
Query: 1520 EAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEM 1579
+ E ++++ + + + ++ + R LEA++ EEEL+E+ G ++ + + +
Sbjct: 1707 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1766
Query: 1580 ERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE-EYEDKQKVLREKRELEGKLAT 1638
E++ + E S ++ E ARQ +++ K++ +L E E K K LE K+A
Sbjct: 1767 EQLSNELATE-RSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ 1825
Query: 1639 LSDQVNRRDFESE---KRLRKDLKRTKALL---ADAQLMLDHLKNSA-PSKREIAQLKNQ 1691
L +QV + E + K L++ K+ K +L D + M + K A + QLK Q
Sbjct: 1826 LEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1885
Query: 1692 LEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1734
LEE+E R+ ++ E+++ + + + AL+ +L
Sbjct: 1886 LEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1928
Score = 58.5 bits (140), Expect = 6e-08
Identities = 96/465 (20%), Positives = 190/465 (40%), Gaps = 106/465 (22%)
Query: 1179 RLEEQRDEQTSRNLTLFQAACRGYLARQHFK------KRKIQDLAIRC--VQKNI---KK 1227
R E + E+ ++ L+L +A A++ + K +++DL V KN+ +K
Sbjct: 1473 RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK 1532
Query: 1228 NKGVKDWPWWKLFTTVRPLI-EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDR 1286
+K + ++ T + L E+Q +E+ + +Q L+ + E+ + R+E R
Sbjct: 1533 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1592
Query: 1287 -LESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDA---------- 1335
L+ ++ E +EL DER A+ A + + E ++K+L+ Q D+
Sbjct: 1593 QLQRQLHEYETELEDERKQRALAA-------AAKKKLEGDLKDLELQADSAIKGREEAIK 1645
Query: 1336 ----LKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGG-----------EWRLKYERAVR 1380
L+ QM+ + E+ +AR R EI +++ E ERA +
Sbjct: 1646 QLRKLQAQMKDFQRELEDARASRD-EIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 1704
Query: 1381 EVDFTKKRLQQEFEDKLEVE---QQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTA 1437
+ D K+ L +E L Q KR+LE R+ L+ + EE Q ++ + + ++ T
Sbjct: 1705 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1764
Query: 1438 ELQDT-------------------KLHLEGQQVRN--HELEKKQRR--------FDSELS 1468
+ + +L + +++R+ HE+E + +++++
Sbjct: 1765 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1824
Query: 1469 QAHEEAQRE----------------KLQREKLQREKDMLLAEAFS------------LKQ 1500
Q E+ ++E KL+ LQ E + +AE + LK+
Sbjct: 1825 QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKR 1884
Query: 1501 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLR 1545
QLEE + + L+ EL + + + +K +LR
Sbjct: 1885 QLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1929
Score = 56.6 bits (135), Expect = 2e-07
Identities = 56/280 (20%), Positives = 130/280 (46%), Gaps = 21/280 (7%)
Query: 1252 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL 1311
+E++ ++ + ++ QL+ L AE+ R + L + L EL S L+ G +A Q
Sbjct: 1678 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE---ELASSLS-----GRNALQ- 1728
Query: 1312 LDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEW 1371
E+ R E + +L+ + + + ME M V +A +A +++ E+ + + +
Sbjct: 1729 -----DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ-QAEQLSNELATERSTAQ- 1781
Query: 1372 RLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKK 1431
K E A ++++ K L+ + E+E K + + + L+A + + ++Q ++
Sbjct: 1782 --KNESARQQLERQNKELRSKLH---EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1836
Query: 1432 CQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDML 1491
Q T L+ L+ ++ + K ++ + + + ++ K Q E+ + E +
Sbjct: 1837 KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRI 1896
Query: 1492 LAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQES 1531
A L+++L+E ++V +L+++L+ QE+
Sbjct: 1897 NANRRKLQRELDEATESNEAMGREVNALKSKLRGPPPQET 1936
>gi|92091586 smooth muscle myosin heavy chain 11 isoform SM1B [Homo
sapiens]
Length = 1979
Score = 597 bits (1540), Expect = e-170
Identities = 495/1757 (28%), Positives = 864/1757 (49%), Gaps = 279/1757 (15%)
Query: 342 AEEAWNETEKVWLV-HRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKAN 400
A+ W VW+ + GF AS +K E+ + +V V+L +G + V +DD++K N
Sbjct: 26 AQADWAAKRLVWVPSEKQGFEAAS-IKEEKGD----EVVVELVENGKKVTVGKDDIQKMN 80
Query: 401 APSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMH 460
P ++ED+A L LNE+SVLH LR+RY + L++TY+G +V+ P +YSEK++
Sbjct: 81 PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140
Query: 461 MFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAG 520
M+KG +R +M PHIYA+A TAYR+ML R+DQSI+ G SG+GKT + + ++QYLA +A
Sbjct: 141 MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200
Query: 521 I-SGNKVFSVEKWQALY------------TLLEAFGNSPTIINGNATRFSQILSLDFDQA 567
G K S+ + + +LEAFGN+ T+ N N++RF + + ++FD
Sbjct: 201 SHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVT 260
Query: 568 GQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHL----NHLAENNV 623
G + A+I+T LLEK R R+ E TF++FYY++A +R++L L N+ +N
Sbjct: 261 GYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNG 320
Query: 624 FGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAE 683
F +P A+ +E F + AM ++G S +EQ + +++++ LG KE
Sbjct: 321 FVPIPAAQDDE------MFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKER-N 373
Query: 684 AGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGG--TLQRSTSFRQGPEESGLGDG 741
+ + AQK +L+G ++ + + +I + K G +Q++ + Q
Sbjct: 374 TDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQTKEQ---------- 423
Query: 742 TGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGG 800
A +E +A Y LF +++ VN+AL + S + I+D GF+ E
Sbjct: 424 ------ADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVN- 476
Query: 801 SARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQ 860
SFE+LC NYT ++LQ+LF+ F+ E E Y+ E IE F D
Sbjct: 477 -----SFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFG------------ 519
Query: 861 ASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLH 920
Q + + R + G+L LL+EE P A++ + +E+L + G K Q P
Sbjct: 520 LDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQGSHP---KFQKPKQL 576
Query: 921 SSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGS 980
K ++ H V+YN + WL +P N LL S K +++L+
Sbjct: 577 KDKTEFSII---HYAGKVDYNASAWLT-KNMDPLNDNVTSLLNASSDKFVADLWKD---- 628
Query: 981 ATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSK 1040
I GL+ +++ S KT GM +++ K Q+ L+ T++ +
Sbjct: 629 ----VDRIVGLDQMAKMTESSLPSASKT-KKGMF----RTVGQLYKEQLGKLMTTLRNTT 679
Query: 1041 LHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSR 1100
+FV C +P E +G+ LD L+ QLR +
Sbjct: 680 PNFVRCIIPNHEKRSGK-----------------------------LDAFLVLEQLRCNG 710
Query: 1101 LLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEK 1160
+L+ +R+ RQG+P+ +VF EFR+R+++LA + K +D ++A +++ L+L+
Sbjct: 711 VLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-----FMDGKQACILMIKALELDP 765
Query: 1161 SSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRC 1220
+ +G S++FFR G LA LEE+RD + + + FQA CRGYLAR+ F KR+ Q A++
Sbjct: 766 NLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKV 825
Query: 1221 VQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNEL 1280
+Q+N +++W WW+LFT V+PL++V EE+++ K++E+Q+ + + +KAE E EL
Sbjct: 826 IQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKEL 885
Query: 1281 RLNSDRLESRISELTSE--LTDERNTGESASQLLDAETAERLRAEK-EMKELQTQYDALK 1337
E + S+LT E L E+ E+ E RL A+K E++E+ + +A
Sbjct: 886 -------EQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARL 938
Query: 1338 KQMEVMEMEVMEARLIRAAE---INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEF- 1393
++ E ++ R A + + ++++++A + +L+ E+ E K+L+ E
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ-KLQLEKVTAEAKI--KKLEDEIL 995
Query: 1394 --EDKLEVEQQNKRQLERRLGDLQ---ADSEESQRALQQLKKKCQRLTAELQDTKLHLEG 1448
+D+ + ++ LE R+ DL A+ EE + L +LK K + + +EL+ + L+
Sbjct: 996 VMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE---VRLKK 1052
Query: 1449 QQVRNHELEKKQRRFDSELSQAHEE-----AQREKLQREKLQREKDMLLAEAFSLKQQLE 1503
++ ELEK +R+ + + S HE+ AQ +L+ + ++E+++ A A L ++
Sbjct: 1053 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA-RLDDEIA 1111
Query: 1504 EKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDL----EAKVKDQEEELD 1559
+K+ + +K+ LE + D+ + A+ K +KQ RDL EA + E+ LD
Sbjct: 1112 QKNNAL----KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1167
Query: 1560 ------------EQAGTI--QMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQ 1605
EQ T+ + L++ E +++ MRQ H++ +E E++E+ +++ +
Sbjct: 1168 STATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRA-K 1226
Query: 1606 KKLKQMEVQLEEEYED-----------KQKVLREKRELEGKL--------------ATLS 1640
L + + LE+E D KQ+V +K++LE ++ A L+
Sbjct: 1227 ANLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286
Query: 1641 DQVNRRDFESEK-------------RLRKDLKRTKALLADAQLML--------------- 1672
D+V++ E E +L KD+ + L D Q +L
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346
Query: 1673 ----------DHLKNSAPSKR-----------EIAQLKNQLEESEFTCAAAVKARKAMEV 1711
D L +K+ +++ K +L++ T A + +K +
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1406
Query: 1712 EIEDLHLQIDDIAKAKTALEEQLSRLQRE----------KNEIQNRLEEDQEDMNELMKK 1761
EIE+L Q ++ A A LE+ +RLQ+E + ++ + LE+ Q ++L+ +
Sbjct: 1407 EIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAE 1466
Query: 1762 HK-----------AAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQS 1810
K A A+A + L LEEA + K+EL+ + L++++E L S
Sbjct: 1467 EKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSS 1526
Query: 1811 MVDKSL-VSRQEAKIRELETRLEFERTQVKRLESLAS-------RLKENMEKLTEERDQR 1862
D V E R LET++E +TQ++ LE RL+ NM+ L + ++
Sbjct: 1527 KDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERD 1586
Query: 1863 IAAENREKEQNKR-LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQAD 1921
+ A + + E+ +R LQRQL + + E+ + ++ A A+ K +LE DL+ LE S
Sbjct: 1587 LQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKG 1646
Query: 1922 LKLAFKRIGDLQAAIED 1938
+ A K++ LQA ++D
Sbjct: 1647 REEAIKQLRKLQAQMKD 1663
Score = 231 bits (589), Expect = 5e-60
Identities = 189/738 (25%), Positives = 372/738 (50%), Gaps = 61/738 (8%)
Query: 1224 NIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE-EIQQLRSKLEKAEKERNELRL 1282
N+ KNK + L +R L + + E + K E ++Q+L+SK E+ R EL
Sbjct: 1228 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELND 1287
Query: 1283 NSDRLESRISELTSELTDERNTG--------------ESASQLLDAETAERLRAEKEMKE 1328
+L++ + +T L + + +LL ET ++L ++++
Sbjct: 1288 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1347
Query: 1329 LQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKR 1388
L+ + ++L+ Q++ EME + + +N ++ D +KK+
Sbjct: 1348 LEEERNSLQDQLDE-EMEAKQNLERHISTLNIQLSD--------------------SKKK 1386
Query: 1389 LQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEG 1448
LQ +F +E ++ K++ ++ + +L EE A +L+K RL EL D + L+
Sbjct: 1387 LQ-DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1445
Query: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD 1508
Q+ LEKKQR+FD L++ + + +R++ + E +A SL + LEE
Sbjct: 1446 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1505
Query: 1509 IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
+ L+AE++D+ S + ++ +++K R LE ++++ + +L+E +Q
Sbjct: 1506 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1565
Query: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
E AKLRLE+ M+ ++ +++++RDE+ EE R+ Q++L + E +LE+E + +
Sbjct: 1566 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1625
Query: 1629 KRELEGKLATL---SDQVNRRDFESEKRLRK---DLKRTKALLADAQLMLDHLKNSA-PS 1681
K++LEG L L +D + E+ K+LRK +K + L DA+ D + +A +
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1685
Query: 1682 KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1741
+++ L+ L + + AAA +ARK ++E E+L ++ + AL+++ RL+
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1745
Query: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQ 1801
+++ LEE+Q +M + + + A QA + ++ ++ ++ +Q+L+ + + L+
Sbjct: 1746 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1805
Query: 1802 SQVEFLEQSMVD--KSLVSRQEAKIRELETRLEFE-RTQVKRLESLASRLKENMEKLTEE 1858
S++ +E ++ KS ++ EAKI +LE ++E E R + +SL + K+ E L +
Sbjct: 1806 SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQV 1865
Query: 1859 RDQRIAAENREKEQN------KRLQRQLRDTKEEMGELARKEAEASRKKHELEMD--LES 1910
D+R AE +++ K+L+RQL + +EE + A+R+K + E+D ES
Sbjct: 1866 EDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE-----SQRINANRRKLQRELDEATES 1920
Query: 1911 LEAANQSLQADLKLAFKR 1928
EA + + A LK +R
Sbjct: 1921 NEAMGREVNA-LKSKLRR 1937
Score = 173 bits (438), Expect = 2e-42
Identities = 185/813 (22%), Positives = 352/813 (43%), Gaps = 137/813 (16%)
Query: 1254 EQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL-- 1311
EQI + +I +L+ +L K E+E L+ RL+ I++ + L R S L
Sbjct: 1076 EQIADLQAQIAELKMQLAKKEEE---LQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1132
Query: 1312 -LDAETAERLRAEKEMKELQTQYDALKKQME------VMEMEVMEARLIRAAEINGEVDD 1364
LD+E A R +AEK+ ++L + +ALK ++E + E+ R + +D+
Sbjct: 1133 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1192
Query: 1365 DDAGGE-----WRLKYERAVRE--------------VDFTKKRLQQEFED---------- 1395
+ E R K+ +AV E +D K+ L++E D
Sbjct: 1193 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1252
Query: 1396 -KLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRL------------------- 1435
K EVE + K++LE ++ +LQ+ + +RA +L K +L
Sbjct: 1253 AKQEVEHK-KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI 1311
Query: 1436 ---------TAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQR 1486
+++LQDT+ L+ + + + K R+ + E + ++ E ++ L+R
Sbjct: 1312 KLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLER 1371
Query: 1487 EKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRD 1546
L + K++L++ + + + E+++++ Q + A+ K++K
Sbjct: 1372 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1431
Query: 1547 LEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQK 1606
L+ ++ D +LD Q + LE+ + + + + + SK + RD EAR+ K
Sbjct: 1432 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1491
Query: 1607 KLKQMEVQLEEEYEDKQKVLREKRELEGKLATL---SDQVNRRDFESEKRLR-------- 1655
L LEE E K+++ R + L+ ++ L D V + E EK R
Sbjct: 1492 ALSLARA-LEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE 1550
Query: 1656 -----KDLKRTKALLADAQLMLD--------------------HLKNSAPSKREIAQLKN 1690
++L+ DA+L L+ + + +R++ + +
Sbjct: 1551 MKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYET 1610
Query: 1691 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1750
+LE+ A A A+K +E +++DL LQ D K + +QL +LQ + + Q LE+
Sbjct: 1611 ELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1670
Query: 1751 DQEDMNELM---KKHKAAVAQASRDLAQINDLQAQLEEANK----EKQELQEKLQALQSQ 1803
+ +E+ K+++ DL Q+ + A E A K EK+EL E+L + S
Sbjct: 1671 ARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG 1730
Query: 1804 VEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQR 1862
L+ R EA+I +LE LE E+ ++ + + + E+L+ E +R
Sbjct: 1731 RNALQDEK------RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1784
Query: 1863 IAAENRE--KEQNKRLQRQLRDTKEEM---------GELARKEAEASRKKHELEMDLESL 1911
A+ E ++Q +R ++LR EM +A EA+ ++ + ++E +
Sbjct: 1785 STAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREK 1844
Query: 1912 EAANQSLQADLKLAFKRIGDLQAAIEDEMESDE 1944
+AA +SL K K++ ++ +EDE + E
Sbjct: 1845 QAATKSL----KQKDKKLKEILLQVEDERKMAE 1873
>gi|92091583 smooth muscle myosin heavy chain 11 isoform SM2B [Homo
sapiens]
Length = 1945
Score = 597 bits (1538), Expect = e-170
Identities = 462/1691 (27%), Positives = 838/1691 (49%), Gaps = 194/1691 (11%)
Query: 342 AEEAWNETEKVWLV-HRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKAN 400
A+ W VW+ + GF AS +K E+ + +V V+L +G + V +DD++K N
Sbjct: 26 AQADWAAKRLVWVPSEKQGFEAAS-IKEEKGD----EVVVELVENGKKVTVGKDDIQKMN 80
Query: 401 APSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMH 460
P ++ED+A L LNE+SVLH LR+RY + L++TY+G +V+ P +YSEK++
Sbjct: 81 PPKFSKVEDMAELTCLNEASVLHNLRERYFSGLIYTYSGLFCVVVNPYKHLPIYSEKIVD 140
Query: 461 MFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAG 520
M+KG +R +M PHIYA+A TAYR+ML R+DQSI+ G SG+GKT + + ++QYLA +A
Sbjct: 141 MYKGKKRHEMPPHIYAIADTAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAVVAS 200
Query: 521 I-SGNKVFSVEKWQAL------------YTLLEAFGNSPTIINGNATRFSQILSLDFDQA 567
G K S+ + + +LEAFGN+ T+ N N++RF + + ++FD
Sbjct: 201 SHKGKKDTSITQGPSFAYGELEKQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVT 260
Query: 568 GQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHL----NHLAENNV 623
G + A+I+T LLEK R R+ E TF++FYY++A +R++L L N+ +N
Sbjct: 261 GYIVGANIETYLLEKSRAIRQARDERTFHIFYYMIAGAKEKMRSDLLLEGFNNYTFLSNG 320
Query: 624 FGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAE 683
F +P A+ +E F + AM ++G S +EQ + +++++ LG KE
Sbjct: 321 FVPIPAAQDDE------MFQETVEAMAIMGFSEEEQLSILKVVSSVLQLGNIVFKKE-RN 373
Query: 684 AGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGG--TLQRSTSFRQGPEESGLGDG 741
+ + AQK +L+G ++ + + +I + K G +Q++ +
Sbjct: 374 TDQASMPDNTAAQKVCHLMGINVTDFTRSILTPRIKVGRDVVQKAQT------------- 420
Query: 742 TGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGG 800
K A +E +A Y LF +++ VN+AL + S + I+D GF+ E
Sbjct: 421 ---KEQADFAVEALAKATYERLFRWILTRVNKALDKTHRQGASFLGILDIAGFEIFEVN- 476
Query: 801 SARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQ 860
SFE+LC NYT ++LQ+LF+ F+ E E Y+ E IE F D
Sbjct: 477 -----SFEQLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDF------------G 519
Query: 861 ASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLH 920
Q + + R + G+L LL+EE P A++ + +E+L + G K Q P
Sbjct: 520 LDLQPCIELIERPNNPPGVLALLDEECWFPKATDKSFVEKLCTEQG---SHPKFQKPKQL 576
Query: 921 SSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGS 980
K ++ H V+YN + WL +P N LL S K +++L+
Sbjct: 577 KDKTEFSII---HYAGKVDYNASAWLT-KNMDPLNDNVTSLLNASSDKFVADLWKD---- 628
Query: 981 ATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSK 1040
I GL+ +++ S KT GM +++ K Q+ L+ T++ +
Sbjct: 629 ----VDRIVGLDQMAKMTESSLPSASKT-KKGMF----RTVGQLYKEQLGKLMTTLRNTT 679
Query: 1041 LHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSR 1100
+FV C +P E +G +LD L+ QLR +
Sbjct: 680 PNFVRCIIPNHEKRSG-----------------------------KLDAFLVLEQLRCNG 710
Query: 1101 LLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEK 1160
+L+ +R+ RQG+P+ +VF EFR+R+++LA + K +D ++A +++ L+L+
Sbjct: 711 VLEGIRICRQGFPNRIVFQEFRQRYEILAANAIPKG-----FMDGKQACILMIKALELDP 765
Query: 1161 SSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRC 1220
+ +G S++FFR G LA LEE+RD + + + FQA CRGYLAR+ F KR+ Q A++
Sbjct: 766 NLYRIGQSKIFFRTGVLAHLEEERDLKITDVIMAFQAMCRGYLARKAFAKRQQQLTAMKV 825
Query: 1221 VQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNEL 1280
+Q+N +++W WW+LFT V+PL++V EE+++ K++E+Q+ + + +KAE E E
Sbjct: 826 IQRNCAAYLKLRNWQWWRLFTKVKPLLQVTRQEEEMQAKEDELQKTKERQQKAENELKE- 884
Query: 1281 RLNSDRLESRISELTSE--LTDERNTGESASQLLDAETAERLRAEK-EMKELQTQYDALK 1337
LE + S+LT E L E+ E+ E RL A+K E++E+ + +A
Sbjct: 885 ------LEQKHSQLTEEKNLLQEQLQAETELYAEAEEMRVRLAAKKQELEEILHEMEARL 938
Query: 1338 KQMEVMEMEVMEARLIRA---AEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQE-- 1392
++ E ++ R A ++ ++++++A + +L+ E+ E K+L+ E
Sbjct: 939 EEEEDRGQQLQAERKKMAQQMLDLEEQLEEEEAARQ-KLQLEKVTAEAKI--KKLEDEIL 995
Query: 1393 -FEDKLEVEQQNKRQLERRLGDLQ---ADSEESQRALQQLKKKCQRLTAELQDTKLHLEG 1448
+D+ + ++ LE R+ DL A+ EE + L +LK K + + +EL+ + L+
Sbjct: 996 VMDDQNNKLSKERKLLEERISDLTTNLAEEEEKAKNLTKLKNKHESMISELE---VRLKK 1052
Query: 1449 QQVRNHELEKKQRRFDSELSQAHE-----EAQREKLQREKLQREKDMLLAEAFSLKQQLE 1503
++ ELEK +R+ + + S HE +AQ +L+ + ++E+++ A A L ++
Sbjct: 1053 EEKSRQELEKLKRKLEGDASDFHEQIADLQAQIAELKMQLAKKEEELQAALA-RLDDEIA 1111
Query: 1504 EKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAG 1563
+K+ + +K+ LE + D+ + A+ K +KQ RDL +++ + EL++
Sbjct: 1112 QKNNAL----KKIRELEGHISDLQEDLDSERAARNKAEKQKRDLGEELEALKTELEDTLD 1167
Query: 1564 TIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY---- 1619
+ ++ + + E E+ +++ +E S + +V+E RQ + ++++ QLE+
Sbjct: 1168 STATQQELRAKREQEVTVLKKALDEETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKA 1227
Query: 1620 ---EDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLK 1676
++KQ + +E +L G+L L Q + +K+L ++ ++ +D + L
Sbjct: 1228 NLDKNKQTLEKENADLAGELRVLG-QAKQEVEHKKKKLEAQVQELQSKCSDGERARAELN 1286
Query: 1677 NSAPS-KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1735
+ + E+ + L E+E K ++ +++D + + + K + +L
Sbjct: 1287 DKVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLR 1346
Query: 1736 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1795
+L+ E+N +Q++L+E+ E L + Q S ++ D + +E + K+ Q+
Sbjct: 1347 QLEEERNSLQDQLDEEMEAKQNLERHISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQK 1406
Query: 1796 KLQALQSQVEFLEQSMVDK--SLVSRQEAKIRELETRLEFERTQVKRLE-------SLAS 1846
+++ L Q E + + DK +R + ++ +L L+ +R V LE L +
Sbjct: 1407 EIENLTQQYE-EKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLA 1465
Query: 1847 RLKENMEKLTEERDQRIAAENREK---------------EQNKRLQRQLRDTKEEMGELA 1891
K K +ERD R AE REK E + L+R + K EM +L
Sbjct: 1466 EEKNISSKYADERD-RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLV 1524
Query: 1892 RKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINS 1951
+ + + HELE +LE + ++ L+ + +LQA + ++ + N +
Sbjct: 1525 SSKDDVGKNVHELEKSKRALETQMEEMKTQLE---ELEDELQATEDAKLRLEVNMQALKG 1581
Query: 1952 EGDSDVDSELE 1962
+ + D+ + E
Sbjct: 1582 QFERDLQARDE 1592
Score = 231 bits (588), Expect = 7e-60
Identities = 187/730 (25%), Positives = 367/730 (50%), Gaps = 60/730 (8%)
Query: 1224 NIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE-EIQQLRSKLEKAEKERNELRL 1282
N+ KNK + L +R L + + E + K E ++Q+L+SK E+ R EL
Sbjct: 1228 NLDKNKQTLEKENADLAGELRVLGQAKQEVEHKKKKLEAQVQELQSKCSDGERARAELND 1287
Query: 1283 NSDRLESRISELTSELTDERNTG--------------ESASQLLDAETAERLRAEKEMKE 1328
+L++ + +T L + + +LL ET ++L ++++
Sbjct: 1288 KVHKLQNEVESVTGMLNEAEGKAIKLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQ 1347
Query: 1329 LQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKR 1388
L+ + ++L+ Q++ EME + + +N ++ D +KK+
Sbjct: 1348 LEEERNSLQDQLDE-EMEAKQNLERHISTLNIQLSD--------------------SKKK 1386
Query: 1389 LQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEG 1448
LQ +F +E ++ K++ ++ + +L EE A +L+K RL EL D + L+
Sbjct: 1387 LQ-DFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDN 1445
Query: 1449 QQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD 1508
Q+ LEKKQR+FD L++ + + +R++ + E +A SL + LEE
Sbjct: 1446 QRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEA 1505
Query: 1509 IAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
+ L+AE++D+ S + ++ +++K R LE ++++ + +L+E +Q
Sbjct: 1506 KEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEEMKTQLEELEDELQAT 1565
Query: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
E AKLRLE+ M+ ++ +++++RDE+ EE R+ Q++L + E +LE+E + +
Sbjct: 1566 EDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYETELEDERKQRALAAAA 1625
Query: 1629 KRELEGKLATL---SDQVNRRDFESEKRLRK---DLKRTKALLADAQLMLDHLKNSAPSK 1682
K++LEG L L +D + E+ K+LRK +K + L DA+ D + +A
Sbjct: 1626 KKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELEDARASRDEIFATAKEN 1685
Query: 1683 REIAQ-LKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1741
+ A+ L+ L + + AAA +ARK ++E E+L ++ + AL+++ RL+
Sbjct: 1686 EKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSGRNALQDEKRRLEARI 1745
Query: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQ 1801
+++ LEE+Q +M + + + A QA + ++ ++ ++ +Q+L+ + + L+
Sbjct: 1746 AQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATERSTAQKNESARQQLERQNKELR 1805
Query: 1802 SQVEFLEQSMVDK--SLVSRQEAKIRELETRLEFE-RTQVKRLESLASRLKENMEKLTEE 1858
S++ +E ++ K S ++ EAKI +LE ++E E R + +SL + K+ E L +
Sbjct: 1806 SKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREKQAATKSLKQKDKKLKEILLQV 1865
Query: 1859 RDQRIAAENREKEQNK------RLQRQLRDTKEEMGELARKEAEASRKKHELEMD--LES 1910
D+R AE +++ K +L+RQL + +EE + A+R+K + E+D ES
Sbjct: 1866 EDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEE-----SQRINANRRKLQRELDEATES 1920
Query: 1911 LEAANQSLQA 1920
EA + + A
Sbjct: 1921 NEAMGREVNA 1930
Score = 179 bits (455), Expect = 2e-44
Identities = 197/856 (23%), Positives = 373/856 (43%), Gaps = 62/856 (7%)
Query: 1180 LEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKL 1239
LEEQ +E+ + L A KK + + L + + K + + + L
Sbjct: 962 LEEQLEEEEAARQKL---QLEKVTAEAKIKKLEDEILVMDDQNNKLSKERKLLEERISDL 1018
Query: 1240 FTTVRPLIEVQLSEEQIRNKDEE-IQQLRSKLEKAEKERNEL-----RLNSDR------- 1286
T + E + +++NK E I +L +L+K EK R EL +L D
Sbjct: 1019 TTNLAEEEEKAKNLTKLKNKHESMISELEVRLKKEEKSRQELEKLKRKLEGDASDFHEQI 1078
Query: 1287 --LESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQM---- 1340
L+++I+EL +L + ++A LD E A++ A K+++EL+ L++ +
Sbjct: 1079 ADLQAQIAELKMQLAKKEEELQAALARLDDEIAQKNNALKKIRELEGHISDLQEDLDSER 1138
Query: 1341 ------EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE 1394
E + ++ E E+ +D E R K E+ EV KK L +E
Sbjct: 1139 AARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQ---EVTVLKKALDEETR 1195
Query: 1395 DKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNH 1454
Q+ +++ + + +L E+ +RA L K Q L E D L
Sbjct: 1196 SHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQAKQ 1255
Query: 1455 ELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQ 1514
E+E K+++ ++++ + + + R +L + L E S+ L E + +
Sbjct: 1256 EVEHKKKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAIKLAK 1315
Query: 1515 KVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLR 1574
V SL ++LQD ++ V +LR LE + +++LDE+ Q LE+
Sbjct: 1316 DVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLERHIST 1375
Query: 1575 LEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEG 1634
L +++ ++ ++ S E +EE ++ QK+++ + Q EE+ K+ + K L+
Sbjct: 1376 LNIQLSDSKKK-LQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQ 1434
Query: 1635 KLATLS-DQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLE 1693
+L L D N+R S L K ++ LLA+ + ++ + +R+ A+ + + +
Sbjct: 1435 ELDDLVVDLDNQRQLVSN--LEKKQRKFDQLLAEEK----NISSKYADERDRAEAEAREK 1488
Query: 1694 ESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQE 1753
E++ A+ +A+E +E AK LE L+ E ++ + ++ +
Sbjct: 1489 ETK-----ALSLARALEEALE-----------AKEELERTNKMLKAEMEDLVSSKDDVGK 1532
Query: 1754 DMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVD 1813
+++EL K +A Q Q+ +L+ +L+ K L+ +QAL+ Q E Q+ +
Sbjct: 1533 NVHELEKSKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDE 1592
Query: 1814 KSLVSRQEAK--IRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKE 1871
++ R++ + + E ET LE ER Q + +L+ +++ L + D I +
Sbjct: 1593 QNEEKRRQLQRQLHEYETELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIK 1652
Query: 1872 QNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLA--FKRI 1929
Q ++LQ Q++D + E+ + E E E +SLEA LQ DL A ++
Sbjct: 1653 QLRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQ 1712
Query: 1930 GDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAASDDGSLK 1989
DL+ ++E+ + L D LE R+ ++ L + +G +A SD
Sbjct: 1713 ADLE---KEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKA 1769
Query: 1990 SSSPTSYWKSLAPDRS 2005
+ LA +RS
Sbjct: 1770 TQQAEQLSNELATERS 1785
Score = 173 bits (438), Expect = 2e-42
Identities = 185/813 (22%), Positives = 352/813 (43%), Gaps = 137/813 (16%)
Query: 1254 EQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL-- 1311
EQI + +I +L+ +L K E+E L+ RL+ I++ + L R S L
Sbjct: 1076 EQIADLQAQIAELKMQLAKKEEE---LQAALARLDDEIAQKNNALKKIRELEGHISDLQE 1132
Query: 1312 -LDAETAERLRAEKEMKELQTQYDALKKQME------VMEMEVMEARLIRAAEINGEVDD 1364
LD+E A R +AEK+ ++L + +ALK ++E + E+ R + +D+
Sbjct: 1133 DLDSERAARNKAEKQKRDLGEELEALKTELEDTLDSTATQQELRAKREQEVTVLKKALDE 1192
Query: 1365 DDAGGE-----WRLKYERAVRE--------------VDFTKKRLQQEFED---------- 1395
+ E R K+ +AV E +D K+ L++E D
Sbjct: 1193 ETRSHEAQVQEMRQKHAQAVEELTEQLEQFKRAKANLDKNKQTLEKENADLAGELRVLGQ 1252
Query: 1396 -KLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRL------------------- 1435
K EVE + K++LE ++ +LQ+ + +RA +L K +L
Sbjct: 1253 AKQEVEHK-KKKLEAQVQELQSKCSDGERARAELNDKVHKLQNEVESVTGMLNEAEGKAI 1311
Query: 1436 ---------TAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQR 1486
+++LQDT+ L+ + + + K R+ + E + ++ E ++ L+R
Sbjct: 1312 KLAKDVASLSSQLQDTQELLQEETRQKLNVSTKLRQLEEERNSLQDQLDEEMEAKQNLER 1371
Query: 1487 EKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRD 1546
L + K++L++ + + + E+++++ Q + A+ K++K
Sbjct: 1372 HISTLNIQLSDSKKKLQDFASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNR 1431
Query: 1547 LEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQK 1606
L+ ++ D +LD Q + LE+ + + + + + SK + RD EAR+ K
Sbjct: 1432 LQQELDDLVVDLDNQRQLVSNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETK 1491
Query: 1607 KLKQMEVQLEEEYEDKQKVLREKRELEGKLATL---SDQVNRRDFESEKRLR-------- 1655
L LEE E K+++ R + L+ ++ L D V + E EK R
Sbjct: 1492 ALSLARA-LEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEKSKRALETQMEE 1550
Query: 1656 -----KDLKRTKALLADAQLMLD--------------------HLKNSAPSKREIAQLKN 1690
++L+ DA+L L+ + + +R++ + +
Sbjct: 1551 MKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRRQLQRQLHEYET 1610
Query: 1691 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1750
+LE+ A A A+K +E +++DL LQ D K + +QL +LQ + + Q LE+
Sbjct: 1611 ELEDERKQRALAAAAKKKLEGDLKDLELQADSAIKGREEAIKQLRKLQAQMKDFQRELED 1670
Query: 1751 DQEDMNELM---KKHKAAVAQASRDLAQINDLQAQLEEANK----EKQELQEKLQALQSQ 1803
+ +E+ K+++ DL Q+ + A E A K EK+EL E+L + S
Sbjct: 1671 ARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAEELASSLSG 1730
Query: 1804 VEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEE-RDQR 1862
L+ R EA+I +LE LE E+ ++ + + + E+L+ E +R
Sbjct: 1731 RNALQDEK------RRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQAEQLSNELATER 1784
Query: 1863 IAAENRE--KEQNKRLQRQLRDTKEEM---------GELARKEAEASRKKHELEMDLESL 1911
A+ E ++Q +R ++LR EM +A EA+ ++ + ++E +
Sbjct: 1785 STAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQLEEQVEQEAREK 1844
Query: 1912 EAANQSLQADLKLAFKRIGDLQAAIEDEMESDE 1944
+AA +SL K K++ ++ +EDE + E
Sbjct: 1845 QAATKSL----KQKDKKLKEILLQVEDERKMAE 1873
Score = 120 bits (301), Expect = 1e-26
Identities = 132/583 (22%), Positives = 263/583 (45%), Gaps = 60/583 (10%)
Query: 1174 AGTLARLEE--QRDEQTSRNLTL-FQAACRGYLARQHFKKRKIQDLAIRCV----QKNIK 1226
A T+ LEE +R ++ NLT ++ Y + K R Q+L V Q+ +
Sbjct: 1391 ASTVEALEEGKKRFQKEIENLTQQYEEKAAAYDKLEKTKNRLQQELDDLVVDLDNQRQLV 1450
Query: 1227 KNKGVKDWPWWKLFTTVRPLI-----EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELR 1281
N K + +L + + E +E + R K+ + L LE+A + + EL
Sbjct: 1451 SNLEKKQRKFDQLLAEEKNISSKYADERDRAEAEAREKETKALSLARALEEALEAKEELE 1510
Query: 1282 LNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQME 1341
+ L++ + +L S D G++ +L EK + L+TQ + +K Q+E
Sbjct: 1511 RTNKMLKAEMEDLVSSKDD---VGKNVHEL-----------EKSKRALETQMEEMKTQLE 1556
Query: 1342 VMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQ 1401
+E E+ +DA +L+ E ++ + K + +++ + + E +
Sbjct: 1557 ELEDELQAT--------------EDA----KLRLEVNMQAL---KGQFERDLQARDEQNE 1595
Query: 1402 QNKRQLERRLGDLQADSEES--QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKK 1459
+ +RQL+R+L + + + E+ QRAL KK +L +L+D +L + E K+
Sbjct: 1596 EKRRQLQRQLHEYETELEDERKQRALAAAAKK--KLEGDLKDLELQADSAIKGREEAIKQ 1653
Query: 1460 QRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSL 1519
R+ +++ E + + R+++ +A SL+ L + D+A +
Sbjct: 1654 LRKLQAQMKDFQRELEDARASRDEIFATAKENEKKAKSLEADLMQLQEDLAAAERARKQA 1713
Query: 1520 EAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEM 1579
+ E ++++ + + + ++ + R LEA++ EEEL+E+ G ++ + + +
Sbjct: 1714 DLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQQA 1773
Query: 1580 ERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE-EYEDKQKVLREKRELEGKLAT 1638
E++ + E S ++ E ARQ +++ K++ +L E E K K LE K+A
Sbjct: 1774 EQLSNELATE-RSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIAQ 1832
Query: 1639 LSDQVNRRDFESE---KRLRKDLKRTKALL---ADAQLMLDHLKNSA-PSKREIAQLKNQ 1691
L +QV + E + K L++ K+ K +L D + M + K A + QLK Q
Sbjct: 1833 LEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQ 1892
Query: 1692 LEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1734
LEE+E R+ ++ E+++ + + + AL+ +L
Sbjct: 1893 LEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKL 1935
Score = 58.5 bits (140), Expect = 6e-08
Identities = 96/465 (20%), Positives = 190/465 (40%), Gaps = 106/465 (22%)
Query: 1179 RLEEQRDEQTSRNLTLFQAACRGYLARQHFK------KRKIQDLAIRC--VQKNI---KK 1227
R E + E+ ++ L+L +A A++ + K +++DL V KN+ +K
Sbjct: 1480 RAEAEAREKETKALSLARALEEALEAKEELERTNKMLKAEMEDLVSSKDDVGKNVHELEK 1539
Query: 1228 NKGVKDWPWWKLFTTVRPLI-EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDR 1286
+K + ++ T + L E+Q +E+ + +Q L+ + E+ + R+E R
Sbjct: 1540 SKRALETQMEEMKTQLEELEDELQATEDAKLRLEVNMQALKGQFERDLQARDEQNEEKRR 1599
Query: 1287 -LESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDA---------- 1335
L+ ++ E +EL DER A+ A + + E ++K+L+ Q D+
Sbjct: 1600 QLQRQLHEYETELEDERKQRALAA-------AAKKKLEGDLKDLELQADSAIKGREEAIK 1652
Query: 1336 ----LKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGG-----------EWRLKYERAVR 1380
L+ QM+ + E+ +AR R EI +++ E ERA +
Sbjct: 1653 QLRKLQAQMKDFQRELEDARASRD-EIFATAKENEKKAKSLEADLMQLQEDLAAAERARK 1711
Query: 1381 EVDFTKKRLQQEFEDKLEVE---QQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTA 1437
+ D K+ L +E L Q KR+LE R+ L+ + EE Q ++ + + ++ T
Sbjct: 1712 QADLEKEELAEELASSLSGRNALQDEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ 1771
Query: 1438 ELQDT-------------------KLHLEGQQVRN--HELEKKQRR--------FDSELS 1468
+ + +L + +++R+ HE+E + +++++
Sbjct: 1772 QAEQLSNELATERSTAQKNESARQQLERQNKELRSKLHEMEGAVKSKFKSTIAALEAKIA 1831
Query: 1469 QAHEEAQRE----------------KLQREKLQREKDMLLAEAFS------------LKQ 1500
Q E+ ++E KL+ LQ E + +AE + LK+
Sbjct: 1832 QLEEQVEQEAREKQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKR 1891
Query: 1501 QLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLR 1545
QLEE + + L+ EL + + + +K +LR
Sbjct: 1892 QLEEAEEESQRINANRRKLQRELDEATESNEAMGREVNALKSKLR 1936
Score = 56.6 bits (135), Expect = 2e-07
Identities = 56/280 (20%), Positives = 130/280 (46%), Gaps = 21/280 (7%)
Query: 1252 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL 1311
+E++ ++ + ++ QL+ L AE+ R + L + L EL S L+ G +A Q
Sbjct: 1685 NEKKAKSLEADLMQLQEDLAAAERARKQADLEKEELAE---ELASSLS-----GRNALQ- 1735
Query: 1312 LDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEW 1371
E+ R E + +L+ + + + ME M V +A +A +++ E+ + + +
Sbjct: 1736 -----DEKRRLEARIAQLEEELEEEQGNMEAMSDRVRKATQ-QAEQLSNELATERSTAQ- 1788
Query: 1372 RLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKK 1431
K E A ++++ K L+ + E+E K + + + L+A + + ++Q ++
Sbjct: 1789 --KNESARQQLERQNKELRSKLH---EMEGAVKSKFKSTIAALEAKIAQLEEQVEQEARE 1843
Query: 1432 CQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDML 1491
Q T L+ L+ ++ + K ++ + + + ++ K Q E+ + E +
Sbjct: 1844 KQAATKSLKQKDKKLKEILLQVEDERKMAEQYKEQAEKGNARVKQLKRQLEEAEEESQRI 1903
Query: 1492 LAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQES 1531
A L+++L+E ++V +L+++L+ QE+
Sbjct: 1904 NANRRKLQRELDEATESNEAMGREVNALKSKLRGPPPQET 1943
>gi|12667788 myosin, heavy polypeptide 9, non-muscle [Homo sapiens]
Length = 1960
Score = 588 bits (1516), Expect = e-167
Identities = 457/1719 (26%), Positives = 852/1719 (49%), Gaps = 169/1719 (9%)
Query: 342 AEEAWNETEKVWLVH-RDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKAN 400
A+ W + VW+ + GF AS LK E + E + V+L +G + V++DD++K N
Sbjct: 22 AQADWAAKKLVWVPSDKSGFEPAS-LKEE---VGEEAI-VELVENGKKVKVNKDDIQKMN 76
Query: 401 APSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMH 460
P ++ED+A L LNE+SVLH L++RY + L++TY+G +V+ P +YSE+++
Sbjct: 77 PPKFSKVEDMAELTCLNEASVLHNLKERYYSGLIYTYSGLFCVVINPYKNLPIYSEEIVE 136
Query: 461 MFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAG 520
M+KG +R +M PHIYA+ TAYR+M+ R+DQSI+ G SG+GKT + + ++QYLA +A
Sbjct: 137 MYKGKKRHEMPPHIYAITDTAYRSMMQDREDQSILCTGESGAGKTENTKKVIQYLAYVAS 196
Query: 521 ISGNKVFSVEKWQALYT---LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQT 577
+K E + L +LEAFGN+ T+ N N++RF + + ++FD G + A+I+T
Sbjct: 197 SHKSKKDQGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVNGYIVGANIET 256
Query: 578 MLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQK 637
LLEK R R+ E TF++FYYLL+ L+T+L L + + P ++ K
Sbjct: 257 YLLEKSRAIRQAKEERTFHIFYYLLSGAGEHLKTDLLLEPYNKYRFLSNGHVTIPGQQDK 316
Query: 638 AAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQK 697
F + AM+++GI +EQ +++ + LG KE + + AQK
Sbjct: 317 --DMFQETMEAMRIMGIPEEEQMGLLRVISGVLQLGNIVFKKER-NTDQASMPDNTAAQK 373
Query: 698 AAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSALECLEGM 755
++LLG ++ + + I + K G +Q++ + Q A +E +
Sbjct: 374 VSHLLGINVTDFTRGILTPRIKVGRDYVQKAQTKEQ----------------ADFAIEAL 417
Query: 756 AAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASFEELCHNY 814
A Y +F LV +N+AL ++ S + I+D GF+ + SFE+LC NY
Sbjct: 418 AKATYERMFRWLVLRINKALDKTKRQGASFIGILDIAGFEIFDLN------SFEQLCINY 471
Query: 815 TQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTD 874
T ++LQ+LF+ F+ E E Y+ E IE F D + +++ +
Sbjct: 472 TNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIEKPAGPP--------- 522
Query: 875 EARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHG 934
G+L LL+EE P A++ + +E++ G K Q P K ++ H
Sbjct: 523 ---GILALLDEECWFPKATDKSFVEKVMQEQGTHP---KFQKPKQLKDKADFCII---HY 573
Query: 935 TNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGG 994
V+Y WL +P N LL S K +S L+ + + +AG+
Sbjct: 574 AGKVDYKADEWL-MKNMDPLNDNIATLLHQSSDKFVSELW--KDVDRIIGLDQVAGM--- 627
Query: 995 SQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGW 1054
S+ AL A RK + + K+ L L+ T++ + +FV C +P E
Sbjct: 628 SETALPGAFKTRKGMFRTVGQLYKEQLA--------KLMATLRNTNPNFVRCIIPNHEKK 679
Query: 1055 AGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPD 1114
AG+ LD L+ QLR + +L+ +R+ RQG+P+
Sbjct: 680 AGK-----------------------------LDPHLVLDQLRCNGVLEGIRICRQGFPN 710
Query: 1115 HMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRA 1174
+VF EFR+R+++L P+ K +D ++A +++ L+L+ + +G S+VFFRA
Sbjct: 711 RVVFQEFRQRYEILTPNSIPKG-----FMDGKQACVLMIKALELDSNLYRIGQSKVFFRA 765
Query: 1175 GTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDW 1234
G LA LEE+RD + + + FQA CRGYLAR+ F KR+ Q A++ +Q+N +++W
Sbjct: 766 GVLAHLEEERDLKITDVIIGFQACCRGYLARKAFAKRQQQLTAMKVLQRNCAAYLKLRNW 825
Query: 1235 PWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISEL 1294
WW+LFT V+PL++V EE++ K+EE+ ++R K AE E+ +L + +L
Sbjct: 826 QWWRLFTKVKPLLQVSRQEEEMMAKEEELVKVREKQLAAENRLTEMETLQSQLMAEKLQL 885
Query: 1295 TSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIR 1354
+L E A +L TA++ E+ +L+ + + +++ + ++ E + +
Sbjct: 886 QEQLQAETELCAEAEELRARLTAKKQELEEICHDLEARVEEEEERCQHLQAEKKKMQQ-N 944
Query: 1355 AAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQN------KRQLE 1408
E+ +++++++ + +L+ E+ T+ +L++ E+++ +E QN K+ LE
Sbjct: 945 IQELEEQLEEEESARQ-KLQLEKVT-----TEAKLKKLEEEQIILEDQNCKLAKEKKLLE 998
Query: 1409 RRLGDLQ---ADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDS 1465
R+ + + EE ++L +LK K + + +L++ L ++ + ELEK +R+ +
Sbjct: 999 DRIAEFTTNLTEEEEKSKSLAKLKNKHEAMITDLEE---RLRREEKQRQELEKTRRKLEG 1055
Query: 1466 ELSQ-----AHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLE 1520
+ + A +AQ +L+ + ++E+++ A A ++++ +K+M + +K+ LE
Sbjct: 1056 DSTDLSDQIAELQAQIAELKMQLAKKEEELQAALA-RVEEEAAQKNMAL----KKIRELE 1110
Query: 1521 AELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEME 1580
+++ ++ + AS K +KQ RDL +++ + EL++ + ++ + + E E+
Sbjct: 1111 SQISELQEDLESERASRNKAEKQKRDLGEELEALKTELEDTLDSTAAQQELRSKREQEVN 1170
Query: 1581 RMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLS 1640
+++T +E ++ + +++E RQ + ++++ QLE+ K + + K+ LE + L+
Sbjct: 1171 ILKKTLEEEAKTHEAQIQEMRQKHSQAVEELAEQLEQTKRVKANLEKAKQTLENERGELA 1230
Query: 1641 DQV-----NRRDFE-SEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKR-EIAQLKNQLE 1693
++V + D E K++ L+ + + + + L + + E+ + L
Sbjct: 1231 NEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTELADKVTKLQVELDNVTGLLS 1290
Query: 1694 ESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQE 1753
+S+ + K A+E +++D + + + K +L +L +++ EKN + +LEE++E
Sbjct: 1291 QSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTKLKQVEDEKNSFREQLEEEEE 1350
Query: 1754 DMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVD 1813
+ L K+ AQ + ++ D LE A + K++LQ+ L+ L SQ + + D
Sbjct: 1351 AKHNLEKQIATLHAQVADMKKKMEDSVGCLETAEEVKRKLQKDLEGL-SQRHEEKVAAYD 1409
Query: 1814 K--SLVSRQEAKIRELETRLEFERTQV-------KRLESLASRLKENMEKLTEERDQRIA 1864
K +R + ++ +L L+ +R K+ + L + K K EERD R
Sbjct: 1410 KLEKTKTRLQQELDDLLVDLDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERD-RAE 1468
Query: 1865 AENREK---------------EQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLE 1909
AE REK EQ L+R + + EM +L + + + HELE
Sbjct: 1469 AEAREKETKALSLARALEEAMEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKR 1528
Query: 1910 SLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVK 1969
+LE + ++ L+ + +LQA + ++ + N + ++ + D+ +++ + K
Sbjct: 1529 ALEQQVEEMKTQLE---ELEDELQATEDAKLRLEVNLQAMKAQFERDLQGR-DEQSEEKK 1584
Query: 1970 SWLSKNKGPSKAASDDGSLKSSSPTSYWKSLAPDRSDDE 2008
L + +A +D + S + K L D D E
Sbjct: 1585 KQLVRQVREMEAELEDERKQRSMAVAARKKLEMDLKDLE 1623
Score = 213 bits (543), Expect = 1e-54
Identities = 203/796 (25%), Positives = 388/796 (48%), Gaps = 96/796 (12%)
Query: 1221 VQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE-EIQQLRSKLEKAEKERNE 1279
V+ N++K K + +L V+ L++ + E R K E ++Q+L+ K + E+ R E
Sbjct: 1211 VKANLEKAKQTLENERGELANEVKVLLQGKGDSEHKRKKVEAQLQELQVKFNEGERVRTE 1270
Query: 1280 LRLNSDRLE--------------SRISELTSELTDERNTGESASQLLDAETAERLRAEKE 1325
L +L+ S+ S+LT + + + + +LL E ++L +
Sbjct: 1271 LADKVTKLQVELDNVTGLLSQSDSKSSKLTKDFSALESQLQDTQELLQEENRQKLSLSTK 1330
Query: 1326 MKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFT 1385
+K+++ + ++ ++Q+E E E + A ++ +V D
Sbjct: 1331 LKQVEDEKNSFREQLEEEE-EAKHNLEKQIATLHAQVAD--------------------- 1368
Query: 1386 KKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLH 1445
K+ ++ LE ++ KR+L++ L L EE A +L+K RL EL D +
Sbjct: 1369 MKKKMEDSVGCLETAEEVKRKLQKDLEGLSQRHEEKVAAYDKLEKTKTRLQQELDDLLVD 1428
Query: 1446 LEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEK 1505
L+ Q+ LEKKQ++FD L++ + + +R++ + E +A SL + LEE
Sbjct: 1429 LDHQRQSACNLEKKQKKFDQLLAEEKTISAKYAEERDRAEAEAREKETKALSLARALEEA 1488
Query: 1506 DMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTI 1565
A + E++D+ S + S+ +++K R LE +V++ + +L+E +
Sbjct: 1489 MEQKAELERLNKQFRTEMEDLMSSKDDVGKSVHELEKSKRALEQQVEEMKTQLEELEDEL 1548
Query: 1566 QMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKV 1625
Q E AKLRLE+ ++ M+ ++++ RDE+ EE ++ +++++ME +LE+E + +
Sbjct: 1549 QATEDAKLRLEVNLQAMKAQFERDLQGRDEQSEEKKKQLVRQVREMEAELEDERKQRSMA 1608
Query: 1626 LREKRELEGKLATLS---DQVNRRDFESEKRLRKDLKRTKALLADAQLMLDH-------- 1674
+ +++LE L L D N+ E+ K+LRK +A + D LD
Sbjct: 1609 VAARKKLEMDLKDLEAHIDSANKNRDEAIKQLRK----LQAQMKDCMRELDDTRASREEI 1664
Query: 1675 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQI-DDIAKAKTALEEQ 1733
L + +++++ ++ ++ + + AAA +A++ + E ++L +I + K ALEE+
Sbjct: 1665 LAQAKENEKKLKSMEAEMIQLQEELAAAERAKRQAQQERDELADEIANSSGKGALALEEK 1724
Query: 1734 LSRLQREKNEIQNRLEEDQ---EDMNELMKKHKAAVAQASRDL------AQIND-LQAQL 1783
RL+ +++ LEE+Q E +N+ +KK + Q + DL AQ N+ + QL
Sbjct: 1725 -RRLEARIAQLEEELEEEQGNTELINDRLKKANLQIDQINTDLNLERSHAQKNENARQQL 1783
Query: 1784 EEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFE----RTQVK 1839
E NK EL+ KLQ ++ V+ K+ ++ EAKI +LE +L+ E + K
Sbjct: 1784 ERQNK---ELKVKLQEMEGTVK-----SKYKASITALEAKIAQLEEQLDNETKERQAACK 1835
Query: 1840 RLESLASRLKENMEKLTEER---DQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAE 1896
++ +LK+ + ++ +ER +Q ++ + K+L+RQL + +EE + A
Sbjct: 1836 QVRRTEKKLKDVLLQVDDERRNAEQYKDQADKASTRLKQLKRQLEEAEEE-----AQRAN 1890
Query: 1897 ASRKK--HELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGD 1954
ASR+K ELE E+ +A N+ + + LK +R GDL + M GD
Sbjct: 1891 ASRRKLQRELEDATETADAMNREV-SSLKNKLRR-GDLPFVVPRRMAR-------KGAGD 1941
Query: 1955 SDVDSELEDRVDGVKS 1970
D E++ + DG ++
Sbjct: 1942 GS-DEEVDGKADGAEA 1956
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 581 bits (1497), Expect = e-165
Identities = 444/1722 (25%), Positives = 839/1722 (48%), Gaps = 170/1722 (9%)
Query: 341 AAEEAWNETEKVWLV-HRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKA 399
A + W + VW+ R GF AS +K E + +V V+L +G V++DD++K
Sbjct: 25 ATQADWTAKKLVWIPSERHGFEAAS-IKEERGD----EVMVELAENGKKAMVNKDDIQKM 79
Query: 400 NAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVM 459
N P ++ED+A L LNE+SVLH L+ RY + L++TY+G +V+ P +YSE ++
Sbjct: 80 NPPKFSKVEDMAELTCLNEASVLHNLKDRYYSGLIYTYSGLFCVVINPYKNLPIYSENII 139
Query: 460 HMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIA 519
M++G +R +M PHIYA++++AYR ML R+DQSI+ G SG+GKT + + ++QYLA +A
Sbjct: 140 EMYRGKKRHEMPPHIYAISESAYRCMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVA 199
Query: 520 GI-SGNKVFSVE---KWQALYT--LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASA 573
G K ++ + Q L +LE+FGN+ T+ N N++RF + + ++FD G + A
Sbjct: 200 SSHKGRKDHNIPGELERQLLQANPILESFGNAKTVKNDNSSRFGKFIRINFDVTGYIVGA 259
Query: 574 SIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVF--GIVPLAK 631
+I+T LLEK R R+ E TF++FY LL+ L+++L L G +P+
Sbjct: 260 NIETYLLEKSRAVRQAKDERTFHIFYQLLSGAGEHLKSDLLLEGFNNYRFLSNGYIPIPG 319
Query: 632 PEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFAR 691
++K F + AM ++G S +E + +++++ G KE +
Sbjct: 320 QQDKDN----FQETMEAMHIMGFSHEEILSMLKVVSSVLQFGNISFKKER-NTDQASMPE 374
Query: 692 HEWAQKAAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSAL 749
+ AQK +LLG ++ E + AI + K G +Q++ + Q A
Sbjct: 375 NTVAQKLCHLLGMNVMEFTRAILTPRIKVGRDYVQKAQTKEQ----------------AD 418
Query: 750 ECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASFE 808
+E +A Y LF LV +N+AL ++ S + I+D GF+ E SFE
Sbjct: 419 FAVEALAKATYERLFRWLVHRINKALDRTKRQGASFIGILDIAGFEIFELN------SFE 472
Query: 809 ELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVR 868
+LC NYT ++LQ+LF+ F+ E E Y+ E IE F D + +++ ++
Sbjct: 473 QLCINYTNEKLQQLFNHTMFILEQEEYQREGIEWNFIDFGLDLQPCIDLIERPANPP--- 529
Query: 869 SLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFL 928
G+L LL+EE P A++ T +E+L G K Q P K +
Sbjct: 530 ---------GVLALLDEECWFPKATDKTFVEKLVQEQGSHS---KFQKPRQLKDKADFCI 577
Query: 929 LGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSI 988
+ H V+Y WL +P N LL S + ++ L+ I
Sbjct: 578 I---HYAGKVDYKADEWL-MKNMDPLNDNVATLLHQSSDRFVAELWKD--------VDRI 625
Query: 989 AGLE---GGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVH 1045
GL+ G ++ A A +K + + K+SL L+ T++ + +FV
Sbjct: 626 VGLDQVTGMTETAFGSAYKTKKGMFRTVGQLYKESLT--------KLMATLRNTNPNFVR 677
Query: 1046 CFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAM 1105
C +P E AG+ LD L+ QLR + +L+ +
Sbjct: 678 CIIPNHEKRAGK-----------------------------LDPHLVLDQLRCNGVLEGI 708
Query: 1106 RMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCM 1165
R+ RQG+P+ +VF EFR+R+++L P+ K +D ++A E ++ L+L+ + +
Sbjct: 709 RICRQGFPNRIVFQEFRQRYEILTPNAIPKG-----FMDGKQACERMIRALELDPNLYRI 763
Query: 1166 GLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNI 1225
G S++FFRAG LA LEE+RD + + + FQA CRGYLAR+ F K++ Q A++ +Q+N
Sbjct: 764 GQSKIFFRAGVLAHLEEERDLKITDIIIFFQAVCRGYLARKAFAKKQQQLSALKVLQRNC 823
Query: 1226 KKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSD 1285
++ W WW++FT V+PL++V EE+++ KDEE+ +++ K K E E E+
Sbjct: 824 AAYLKLRHWQWWRVFTKVKPLLQVTRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQ 883
Query: 1286 RLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEM 1345
+L + L +L E A ++ A++ E+ + +L+++ + +++ ++++
Sbjct: 884 QLLEEKNILAEQLQAETELFAEAEEMRARLAAKKQELEEILHDLESRVEEEEERNQILQN 943
Query: 1346 EVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQE---FEDKLEVEQQ 1402
E + + ++ ++D+++ G +L+ E+ E K++++E ED+ +
Sbjct: 944 EKKKMQ-AHIQDLEEQLDEEE-GARQKLQLEKVTAEAKI--KKMEEEILLLEDQNSKFIK 999
Query: 1403 NKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRR 1462
K+ +E R+ + + E + + L K + + D + L+ ++ ELEK +R+
Sbjct: 1000 EKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRK 1059
Query: 1463 FDSELSQ-----AHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVV 1517
D E + A +AQ ++L+ + ++E+++ A A + L + + + V
Sbjct: 1060 LDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNA-----LKVVR 1114
Query: 1518 SLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEM 1577
L+A++ ++ ++AS K +KQ RDL +++ + EL++ T ++ + + E
Sbjct: 1115 ELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKREQ 1174
Query: 1578 EMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLA 1637
E+ +++ +E ++ + ++++ RQ L+++ QLE+ K + + K+ LE
Sbjct: 1175 EVAELKKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLETDNK 1234
Query: 1638 TLS------DQVNRRDFESEKRLRKDLKRTKALLADA-QLMLDHLKNSAPSKREIAQLKN 1690
L+ QV K+L ++ A +++ +L ++ + ++ + E+ +
Sbjct: 1235 ELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVST 1294
Query: 1691 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEE 1750
LEE+E K ++E +++D + + + K L ++ +L+ EKN +Q + EE
Sbjct: 1295 LLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQEQQEE 1354
Query: 1751 DQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVE--FLE 1808
++E L K+ A +Q + +++D +E + K++L + +AL ++E L
Sbjct: 1355 EEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEEKALA 1414
Query: 1809 QSMVDKSLVSRQEAKIRELETRLEFER-------TQVKRLESLASRLKENMEKLTEERDQ 1861
++K+ +R + ++ +L L+ +R + K+ + L + K + EERD
Sbjct: 1415 YDKLEKT-KNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERD- 1472
Query: 1862 RIAAENREK---------------EQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEM 1906
R AE REK E + +RQ + + +M +L + + + HELE
Sbjct: 1473 RAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEK 1532
Query: 1907 DLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVD 1966
+LE + ++ L+ + +LQA + ++ + N + ++ + D+ + +++ +
Sbjct: 1533 SKRALEQQVEEMRTQLE---ELEDELQATEDAKLRLEVNMQAMKAQFERDLQTR-DEQNE 1588
Query: 1967 GVKSWLSKNKGPSKAASDDGSLKSSSPTSYWKSLAPDRSDDE 2008
K L K +A +D + + + K + D D E
Sbjct: 1589 EKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLE 1630
Score = 228 bits (580), Expect = 6e-59
Identities = 174/736 (23%), Positives = 373/736 (50%), Gaps = 58/736 (7%)
Query: 1224 NIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNK-DEEIQQLRSKLEKAEKERNELRL 1282
N++KNK + +L V+ L +V+ E R K D ++Q+L +K+ + ++ R EL
Sbjct: 1221 NLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAE 1280
Query: 1283 NSDRLESRISELTSELTDERNTG--------------ESASQLLDAETAERLRAEKEMKE 1328
+ +L++ + +++ L + G + +LL ET ++L +++
Sbjct: 1281 KASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQ 1340
Query: 1329 LQTQYDALKKQMEVME--MEVMEARLI----RAAEINGEVDDDDAGGEWRLKYERAVREV 1382
L+ + ++L++Q E E + +E +++ + A+ +VDDD + +
Sbjct: 1341 LEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLG----------TIESL 1390
Query: 1383 DFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDT 1442
+ KK+L ++ E L +RL EE A +L+K RL EL D
Sbjct: 1391 EEAKKKLLKDAE-----------ALSQRL-------EEKALAYDKLEKTKNRLQQELDDL 1432
Query: 1443 KLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQL 1502
+ L+ Q+ LEKKQ++FD L++ + R +R++ + E +A SL + L
Sbjct: 1433 TVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARAL 1492
Query: 1503 EEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQA 1562
EE F ++ L A+++D+ S + ++ +++K R LE +V++ +L+E
Sbjct: 1493 EEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELE 1552
Query: 1563 GTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDK 1622
+Q E AKLRLE+ M+ M+ +++++RDE+ EE ++ K+++++E +LE+E + +
Sbjct: 1553 DELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQNEEKKRLLIKQVRELEAELEDERKQR 1612
Query: 1623 QKVLREKRELEGKLATLSDQV---NRRDFESEKRLRK---DLKRTKALLADAQLMLDHL- 1675
+ K+++E L L Q+ N+ E K+LRK +K + L +A+ D +
Sbjct: 1613 ALAVASKKKMEIDLKDLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIF 1672
Query: 1676 KNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1735
S S++++ L+ ++ + + A++ +AR+ E E ++L +I + A K+AL ++
Sbjct: 1673 AQSKESEKKLKSLEAEILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKR 1732
Query: 1736 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1795
RL+ +++ LEE+Q +M L + + Q A++ ++ ++++ +Q+L+
Sbjct: 1733 RLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLER 1792
Query: 1796 KLQALQSQVEFLEQSMVD--KSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENME 1853
+ + L+++++ LE ++ K+ +S EAKI +LE +LE E + L R ++ ++
Sbjct: 1793 QNKELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLK 1852
Query: 1854 KLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEA 1913
++ + + ++ KEQ ++ +++ K ++ E + A+ + +L+ +L+
Sbjct: 1853 EIFMQVEDERRHADQYKEQMEKANARMKQLKRQLEEAEEEATRANASRRKLQRELDDATE 1912
Query: 1914 ANQSLQADLKLAFKRI 1929
AN+ L ++ R+
Sbjct: 1913 ANEGLSREVSTLKNRL 1928
Score = 177 bits (450), Expect = 7e-44
Identities = 170/792 (21%), Positives = 368/792 (46%), Gaps = 85/792 (10%)
Query: 1209 KKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLS--EEQIRNKDEEIQQL 1266
+K+ ++D C + ++ + K+ +R EV +S EE+++ +++ Q+L
Sbjct: 1000 EKKLMEDRIAECSSQLAEEEEKAKN------LAKIRNKQEVMISDLEERLKKEEKTRQEL 1053
Query: 1267 RSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEM 1326
K + E +L+ L+++I EL +L + + A D ET + A K +
Sbjct: 1054 EKAKRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARGDDETLHKNNALKVV 1113
Query: 1327 KELQTQYDALKKQMEV----------MEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYE 1376
+ELQ Q L++ E + ++ E E+ +D A E R K E
Sbjct: 1114 RELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTLDTTAAQQELRTKRE 1173
Query: 1377 RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT 1436
+ V E+ KK L++E ++ Q +++ L +L E+++R L+K Q L
Sbjct: 1174 QEVAEL---KKALEEETKNHEAQIQDMRQRHATALEELSEQLEQAKRFKANLEKNKQGLE 1230
Query: 1437 AELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAF 1496
+ ++ ++ Q E E K+++ D+++ + H + R +L + L E
Sbjct: 1231 TDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQNELD 1290
Query: 1497 SLKQQLEEKDMDIAGFTQKVVSLEAELQD----------------------------ISS 1528
++ LEE + F + SLE++LQD +
Sbjct: 1291 NVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSLQE 1350
Query: 1529 QESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSK 1588
Q+ ++E + ++KQ+ L++++ D ++++D+ GTI+ LE+AK +L + E + Q +
Sbjct: 1351 QQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQRLEE 1410
Query: 1589 EMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDF 1648
+ + D+ +E+ + Q++L + V L+ + + + +++++ + LA ++ R
Sbjct: 1411 KALAYDK-LEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAE-EKSISARYA 1468
Query: 1649 ESEKRLRKDL--KRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKAR 1706
E R + K TKAL A+ + + L+ +R+ QL+ +E+
Sbjct: 1469 EERDRAEAEAREKETKALSL-ARALEEALEAKEEFERQNKQLRADMED------------ 1515
Query: 1707 KAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAV 1766
+ +D+ + ++ K+K ALE+Q+ ++ + E+++ L+ ++ L +A
Sbjct: 1516 --LMSSKDDVGKNVHELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMK 1573
Query: 1767 AQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEF-LEQSMVDKSLVSRQEAKIR 1825
AQ RDL Q + E+ ++K+ L ++++ L++++E +Q + + + E ++
Sbjct: 1574 AQFERDL------QTRDEQNEEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLK 1627
Query: 1826 ELETRLEFERTQ----VKRLESLASRLKENMEKLTEERDQR--IAAENREKEQN-KRLQR 1878
+LE ++E +K+L L +++K+ +L E R R I A+++E E+ K L+
Sbjct: 1628 DLEAQIEAANKARDEVIKQLRKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEA 1687
Query: 1879 QLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIED 1938
++ +EE+ R A +++ EL ++ + + +L + + RI L+ +E+
Sbjct: 1688 EILQLQEELASSERARRHAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEE 1747
Query: 1939 EMESDENEDLIN 1950
E N +L+N
Sbjct: 1748 E---QSNMELLN 1756
Score = 115 bits (287), Expect = 6e-25
Identities = 122/584 (20%), Positives = 261/584 (44%), Gaps = 60/584 (10%)
Query: 1175 GTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRK------IQDLAI-----RCVQK 1223
GT+ LEE + + L Q LA +K K + DL + R V
Sbjct: 1385 GTIESLEEAKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVAS 1444
Query: 1224 NI-KKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRL 1282
N+ KK K + + R E +E + R K+ + L LE+A + + E
Sbjct: 1445 NLEKKQKKFDQLLAEEKSISARYAEERDRAEAEAREKETKALSLARALEEALEAKEEFER 1504
Query: 1283 NSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEV 1342
+ +L + + +L S D G++ +L ++ A E++++E++TQ + L+ +++
Sbjct: 1505 QNKQLRADMEDLMSSKDD---VGKNVHELEKSKRA----LEQQVEEMRTQLEELEDELQA 1557
Query: 1343 MEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQ 1402
E +A+L E+N + K + +++ + + E ++
Sbjct: 1558 TE----DAKL--RLEVNMQA----------------------MKAQFERDLQTRDEQNEE 1589
Query: 1403 NKRQLERRLGDLQADSEES--QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQ 1460
KR L +++ +L+A+ E+ QRAL KK ++ +L+D + +E E+ K+
Sbjct: 1590 KKRLLIKQVRELEAELEDERKQRALAVASKK--KMEIDLKDLEAQIEAANKARDEVIKQL 1647
Query: 1461 RRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLE 1520
R+ +++ E + + R+++ + + SL+ ++ + ++A + E
Sbjct: 1648 RKLQAQMKDYQRELEEARASRDEIFAQSKESEKKLKSLEAEILQLQEELASSERARRHAE 1707
Query: 1521 AELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEME 1580
E +++ + + + + + + R LEA++ EEEL+E+ +++L + ++++
Sbjct: 1708 QERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQSNMELLNDRFRKTTLQVD 1767
Query: 1581 RMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE-EYEDKQKVLREKRELEGKLATL 1639
+ + E S ++ + ARQ +++ K+++ +L+E E K K LE K+ L
Sbjct: 1768 TLNAELAAE-RSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALEAKIGQL 1826
Query: 1640 SDQVNRRDFESE------KRLRKDLKRTKALLADAQLMLDHLKNSAP-SKREIAQLKNQL 1692
+Q+ + E +R K LK + D + D K + + QLK QL
Sbjct: 1827 EEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANARMKQLKRQL 1886
Query: 1693 EESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSR 1736
EE+E A +R+ ++ E++D + +++ + L+ +L R
Sbjct: 1887 EEAEEEATRANASRRKLQRELDDATEANEGLSREVSTLKNRLRR 1930
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 531 bits (1369), Expect = e-150
Identities = 480/1777 (27%), Positives = 828/1777 (46%), Gaps = 274/1777 (15%)
Query: 346 WNETEKVWLVHR-DGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSC 404
W VW+ GF A+ L+ E E + V+L G L + D +++ N P
Sbjct: 50 WTARRLVWVPSELHGFEAAA-LRDEG----EEEAEVELAESGRRLRLPRDQIQRMNPPKF 104
Query: 405 DRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKG 464
+ ED+A L LNE+SVLH LR+RY + L++TY+G +V+ P +Y+E ++ M++G
Sbjct: 105 SKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRG 164
Query: 465 CRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI-SG 523
+R ++ PH+YAV + AYR+ML R+DQSI+ G SG+GKT + + ++QYLA +A G
Sbjct: 165 KKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKG 224
Query: 524 NKVFSVE---KWQALYT--LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTM 578
K V + Q L +LEAFGN+ T+ N N++RF + + ++FD AG + A+I+T
Sbjct: 225 RKEPGVPGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYIVGANIETY 284
Query: 579 LLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKA 638
LLEK R R+ E +F++FY LL L+ +L L + P + P ++++
Sbjct: 285 LLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSSSPGQEREL 344
Query: 639 AQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKA 698
F + +++VLG S +E + +++A+ G A K + + AQK
Sbjct: 345 ---FQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI-ALKRERNTDQATMPDNTAAQKL 400
Query: 699 AYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMA 756
LLG + + S A+ + K G +Q++ + Q A LE +A
Sbjct: 401 CRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQ----------------ADFALEALA 444
Query: 757 AGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASFEELCHNYT 815
Y LF LV +NRAL S S + I+D GF+ + SFE+LC NYT
Sbjct: 445 KATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLN------SFEQLCINYT 498
Query: 816 QDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDE 875
++LQ+LF+ FV E E Y+ E I F D + +++ ++
Sbjct: 499 NEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPP---------- 548
Query: 876 ARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGT 935
GLL LL+EE P A++ + +E++ G G K Q P H F + H G
Sbjct: 549 --GLLALLDEECWFPKATDKSFVEKVAQEQG---GHPKFQRPR-HLRDQADFSVLHYAGK 602
Query: 936 NWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGS 995
V+Y WL +P N LL S ++ + ++ G I GLE S
Sbjct: 603 --VDYKANEWL-MKNMDPLNDNVAALLHQSTDRLTAEIWKDVEG--------IVGLEQVS 651
Query: 996 QLA--LRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEG 1053
L R F T + + K+SL L+ T+ + FV C +P E
Sbjct: 652 SLGDGPPGGRPRRGMFRT-VGQLYKESL--------SRLMATLSNTNPSFVRCIVPNHEK 702
Query: 1054 WAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYP 1113
AG+ L+ L+ QLR + +L+ +R+ RQG+P
Sbjct: 703 RAGK-----------------------------LEPRLVLDQLRCNGVLEGIRICRQGFP 733
Query: 1114 DHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFR 1173
+ ++F EFR+R+++L P+ K +D ++A E++++ L+L+ + +G S++FFR
Sbjct: 734 NRILFQEFRQRYEILTPNAIPKG-----FMDGKQACEKMIQALELDPNLYRVGQSKIFFR 788
Query: 1174 AGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKD 1233
AG LA+LEE+RD + + + FQAA RGYLAR+ F+KR+ Q A+R +Q+N ++
Sbjct: 789 AGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRH 848
Query: 1234 WPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQ----------------------------- 1264
W WW+LFT V+PL++V +E ++ + +E+Q
Sbjct: 849 WQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVAQLEEERAR 908
Query: 1265 ---QLRSKLE---KAEKERNELRLNSDRLESRISELTSELTDERNTGESAS--------- 1309
QLR++ E +AE+ R L LE +SEL + + +E
Sbjct: 909 LAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQH 968
Query: 1310 -QLLDA--ETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLI--------RAAEI 1358
Q L+A E E R + +++++ T+ K + +++ +E ++L R AE
Sbjct: 969 IQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEF 1028
Query: 1359 NGEVDDDD----AGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDL 1414
+ + +++ + + RLKYE + +++ RL++E + + E+E+ KR+L+ +L
Sbjct: 1029 SSQAAEEEEKVKSLNKLRLKYEATIADME---DRLRKEEKGRQELEKL-KRRLDGESSEL 1084
Query: 1415 QADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA 1474
Q E Q+ ++L+ + R ELQ E + +L K R + L++A E+
Sbjct: 1085 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1144
Query: 1475 QREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSL--------------- 1519
+ E++ R K ++++ L E +L+ +LE+ +D Q++ S
Sbjct: 1145 ESERVARTKAEKQRRDLGEELEALRGELED-TLDSTNAQQELRSKREQEVTELKKTLEEE 1203
Query: 1520 ----EAELQDISSQESKDEASLAKVKKQLR-----------DLEAKVKDQEEELDEQAGT 1564
EA +Q++ + + LA+ +Q R LEA+V + EL
Sbjct: 1204 TRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTA 1263
Query: 1565 IQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEE----YE 1620
Q EQ + RLE++++ E++ R + E AR +KL++ + +LE E
Sbjct: 1264 RQEGEQRRRRLELQLQ--------EVQGRAGDGERARAEAAEKLQRAQAELENVSGALNE 1315
Query: 1621 DKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAP 1680
+ K +R +EL A L D E+ +L R +A+ A+A + + L+ A
Sbjct: 1316 AESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALG-SRVRAMEAEAAGLREQLEEEAA 1374
Query: 1681 SKR-----------EIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTA 1729
++ ++++ + + EE A +AR+ E E L ++ + +
Sbjct: 1375 ARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVDR 1434
Query: 1730 LEEQLSRLQRE----------KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL------ 1773
LE RLQ+E + ++ + LE+ Q ++L+ + KAAV +A +
Sbjct: 1435 LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAE 1494
Query: 1774 -----AQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSM--VDKSL--------VS 1818
A+ L LEE + ++EL+ + +AL++++E L S V KS+ V+
Sbjct: 1495 GREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELERACRVA 1554
Query: 1819 RQ-----EAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQN 1873
Q A++ ELE L RLE LK E+ + RD+ +E+
Sbjct: 1555 EQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDE------AGEERR 1608
Query: 1874 KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQ 1933
++L +QLRD + E E ++ A + +LE +LE L+A S + A K++ +Q
Sbjct: 1609 RQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQ 1668
Query: 1934 AAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKS 1970
A ++ E+ + E + E + E E R+ G+++
Sbjct: 1669 AQMK-ELWREVEETRTSREEIFSQNRESEKRLKGLEA 1704
Score = 192 bits (489), Expect = 2e-48
Identities = 169/696 (24%), Positives = 332/696 (47%), Gaps = 49/696 (7%)
Query: 1244 RPLIEVQLSEEQIRNKDEEIQQLRS--KLEKAEKERNELRLNSDRLESRISELTSELTDE 1301
R +E+QL E Q R D E + + KL++A+ E + + ES+ L+ EL+
Sbjct: 1271 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1330
Query: 1302 RNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
A +LL ET +L ++ ++ + L++Q+E
Sbjct: 1331 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE-------------------- 1370
Query: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEE 1420
++A R E + ++ R +QE E LE ++ +R+ R L E
Sbjct: 1371 ---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1427
Query: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480
+ +L++ +RL EL D + LE Q+ LEKKQR+FD L++ R +
Sbjct: 1428 KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1487
Query: 1481 REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKV 1540
RE+ + E A A SL + LEE+ ++ +L AEL+ + S + S+ ++
Sbjct: 1488 RERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1547
Query: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600
++ R E D ++ E + E AKLRLE+ ++ ++ H ++++ RDE EE
Sbjct: 1548 ERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1607
Query: 1601 RQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKD 1657
R+ K+L+ EV+ +EE + + + +++LEG+L L Q+ + E+ K+LRK
Sbjct: 1608 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1667
Query: 1658 LKRTKALLADAQLML----DHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEI 1713
+ K L + + + + S++ + L+ ++ + AA+ +AR+ + +
Sbjct: 1668 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDR 1727
Query: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773
+++ ++ + +K A+ E+ +L+ +++ LEE+Q + L +++ + Q
Sbjct: 1728 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLT 1787
Query: 1774 AQINDLQAQLEEANKEKQELQEKLQALQSQV--EFLEQSMVDKSLVSRQEAKIRELETRL 1831
+++ ++ +A +Q+L+ ++Q L+ ++ E K ++ E+K+ + E +L
Sbjct: 1788 TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQL 1847
Query: 1832 EFERTQV----KRLESLASRLKENMEKLTEERDQRIAAENREKEQN-----KRLQRQLRD 1882
E E + K + RLKE + ++ EER R+A + R++ + K+L+RQL +
Sbjct: 1848 EQETRERILSGKLVRRAEKRLKEVVLQVEEER--RVADQLRDQLEKGNLRVKQLKRQLEE 1905
Query: 1883 TKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918
+E E +R +A R + ELE ES E+ N+ +
Sbjct: 1906 AEE---EASRAQAGRRRLQRELEDVTESAESMNREV 1938
Score = 156 bits (394), Expect = 2e-37
Identities = 158/747 (21%), Positives = 329/747 (44%), Gaps = 116/747 (15%)
Query: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
+EQ+ + + ++LR++L + E+E ++ ++L L + + A + L
Sbjct: 1085 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1144
Query: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
++E R +AEK+ ++L + +AL+ ++E +D +A E R
Sbjct: 1145 ESERVARTKAEKQRRDLGEELEALRGELE------------------DTLDSTNAQQELR 1186
Query: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
K E+ V E+ KK L++E Q+ +++ + LG+L E+++R +K
Sbjct: 1187 SKREQEVTEL---KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243
Query: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA---------QREKLQRE- 1482
L AE+ + + L Q E E+++RR + +L + A EKLQR
Sbjct: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303
Query: 1483 ------------------KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524
+L +E A+ ++ L+E+ +V ++EAE
Sbjct: 1304 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1363
Query: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQ 1584
+ Q ++ A+ + ++L+ +A++ + +E+AG ++ E+A+ R E E + Q
Sbjct: 1364 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1423
Query: 1585 THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY------------------EDKQKVL 1626
+++ E+ D +E R+ Q++L + LE++ E+K VL
Sbjct: 1424 RLAEKTETVDR-LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1482
Query: 1627 R-----EKRELEGKLATLSDQVNRRDFESEKRLRKDLKR-TKALLADAQLMLDHLKNSAP 1680
R E+ E EG+ R E E+ R++L+R +AL A+ + +L
Sbjct: 1483 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS------- 1535
Query: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740
SK ++ + ++LE +A + E DL Q+ ++ TA E+ RL+
Sbjct: 1536 SKDDVGKSVHELE----------RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVT 1585
Query: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800
++ + E D + +E ++ + +A+ Q+ D + + +E K++ + L
Sbjct: 1586 VQALKTQHERDLQGRDEAGEERRRQLAK------QLRDAEVERDEERKQRTLAVAARKKL 1639
Query: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860
+ ++E L+ M ++EA VK+L + +++KE ++ E R
Sbjct: 1640 EGELEELKAQMASAGQ-GKEEA---------------VKQLRKMQAQMKELWREVEETRT 1683
Query: 1861 QR--IAAENREKEQN-KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917
R I ++NRE E+ K L+ ++ +EE+ R +A + + E+ ++ + + +
Sbjct: 1684 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1743
Query: 1918 LQADLKLAFKRIGDLQAAIEDEMESDE 1944
+ + + R+G L+ +E+E + E
Sbjct: 1744 ILEEKRQLEGRLGQLEEELEEEQSNSE 1770
Score = 116 bits (291), Expect = 2e-25
Identities = 115/507 (22%), Positives = 228/507 (44%), Gaps = 38/507 (7%)
Query: 1249 VQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESA 1308
V E++ R D+ + + ++ + +A +ER E+R LT L +E+ E
Sbjct: 1460 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1519
Query: 1309 SQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368
+ A AE ++ L++ V E + R A++ D+ A
Sbjct: 1520 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR----AQVTELEDELTAA 1575
Query: 1369 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD--LQADSEESQRALQ 1426
+ +L+ E V+ + K + +++ + + E ++ +RQL ++L D ++ D E QR L
Sbjct: 1576 EDAKLRLEVTVQAL---KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1632
Query: 1427 QLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKL-- 1484
+K +L EL++ K + E K+ R+ +++ + E + + RE++
Sbjct: 1633 VAARK--KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFS 1690
Query: 1485 -QREKDMLL----AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539
RE + L AE L+++L D + + + +++ + + S A
Sbjct: 1691 QNRESEKRLKGLEAEVLRLQEELAASD-------RARRQAQQDRDEMADEVANGNLSKAA 1743
Query: 1540 VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599
+ ++ R LE ++ EEEL+E+ ++L +L +++E + S E S + E
Sbjct: 1744 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE-RSFSAKAES 1802
Query: 1600 ARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE---LEGKLATLSDQVNRRDFE---SEKR 1653
RQ +++++++ +L EE D R K LE KLA +Q+ + E S K
Sbjct: 1803 GRQQLERQIQELRGRLGEE--DAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1860
Query: 1654 LRKDLKRTKALLADAQ---LMLDHLKNSAPSKR-EIAQLKNQLEESEFTCAAAVKARKAM 1709
+R+ KR K ++ + + D L++ + QLK QLEE+E + A R+ +
Sbjct: 1861 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1920
Query: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSR 1736
+ E+ED+ + + + T L +L R
Sbjct: 1921 QRELEDVTESAESMNREVTTLRNRLRR 1947
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 528 bits (1361), Expect = e-149
Identities = 478/1785 (26%), Positives = 827/1785 (46%), Gaps = 282/1785 (15%)
Query: 346 WNETEKVWLVHR-DGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSC 404
W VW+ GF A+ L+ E E + V+L G L + D +++ N P
Sbjct: 50 WTARRLVWVPSELHGFEAAA-LRDEG----EEEAEVELAESGRRLRLPRDQIQRMNPPKF 104
Query: 405 DRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKG 464
+ ED+A L LNE+SVLH LR+RY + L++TY+G +V+ P +Y+E ++ M++G
Sbjct: 105 SKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRG 164
Query: 465 CRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI-SG 523
+R ++ PH+YAV + AYR+ML R+DQSI+ G SG+GKT + + ++QYLA +A G
Sbjct: 165 KKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKG 224
Query: 524 NKVFSVEKWQALYT-------------LLEAFGNSPTIINGNATRFSQILSLDFDQAGQV 570
K V + + +LEAFGN+ T+ N N++RF + + ++FD AG +
Sbjct: 225 RKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYI 284
Query: 571 ASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLA 630
A+I+T LLEK R R+ E +F++FY LL L+ +L L + P +
Sbjct: 285 VGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS 344
Query: 631 KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690
P ++++ F + +++VLG S +E + +++A+ G A K +
Sbjct: 345 SPGQEREL---FQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI-ALKRERNTDQATMP 400
Query: 691 RHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSA 748
+ AQK LLG + + S A+ + K G +Q++ + Q A
Sbjct: 401 DNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQ----------------A 444
Query: 749 LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807
LE +A Y LF LV +NRAL S S + I+D GF+ + SF
Sbjct: 445 DFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLN------SF 498
Query: 808 EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867
E+LC NYT ++LQ+LF+ FV E E Y+ E I F D + +++ ++
Sbjct: 499 EQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPP-- 556
Query: 868 RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927
GLL LL+EE P A++ + +E++ G G K Q P H F
Sbjct: 557 ----------GLLALLDEECWFPKATDKSFVEKVAQEQG---GHPKFQRPR-HLRDQADF 602
Query: 928 LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGS 987
+ H G V+Y WL +P N LL S ++ + ++ G
Sbjct: 603 SVLHYAGK--VDYKANEWL-MKNMDPLNDNVAALLHQSTDRLTAEIWKDVEG-------- 651
Query: 988 IAGLEGGSQLA--LRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVH 1045
I GLE S L R F T + + K+SL L+ T+ + FV
Sbjct: 652 IVGLEQVSSLGDGPPGGRPRRGMFRT-VGQLYKESL--------SRLMATLSNTNPSFVR 702
Query: 1046 CFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAM 1105
C +P E AG+ L+ L+ QLR + +L+ +
Sbjct: 703 CIVPNHEKRAGK-----------------------------LEPRLVLDQLRCNGVLEGI 733
Query: 1106 RMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCM 1165
R+ RQG+P+ ++F EFR+R+++L P+ K +D ++A E++++ L+L+ + +
Sbjct: 734 RICRQGFPNRILFQEFRQRYEILTPNAIPKG-----FMDGKQACEKMIQALELDPNLYRV 788
Query: 1166 GLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNI 1225
G S++FFRAG LA+LEE+RD + + + FQAA RGYLAR+ F+KR+ Q A+R +Q+N
Sbjct: 789 GQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAARGYLARRAFQKRQQQQSALRVMQRNC 848
Query: 1226 KKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQ--------------------- 1264
++ W WW+LFT V+PL++V +E ++ + +E+Q
Sbjct: 849 AAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQARAQELQKVQELQQQSAREVGELQGRVA 908
Query: 1265 -----------QLRSKLE---KAEKERNELRLNSDRLESRISELTSELTDERNTGESAS- 1309
QLR++ E +AE+ R L LE +SEL + + +E
Sbjct: 909 QLEEERARLAEQLRAEAELCAEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQT 968
Query: 1310 ---------QLLDA--ETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLI----- 1353
Q L+A E E R + +++++ T+ K + +++ +E ++L
Sbjct: 969 EKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLEDQNSKLSKERKL 1028
Query: 1354 ---RAAEINGEVDDDD----AGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQ 1406
R AE + + +++ + + RLKYE + +++ RL++E + + E+E+ KR+
Sbjct: 1029 LEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIADME---DRLRKEEKGRQELEKL-KRR 1084
Query: 1407 LERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSE 1466
L+ +LQ E Q+ ++L+ + R ELQ E + +L K R +
Sbjct: 1085 LDGESSELQEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAA 1144
Query: 1467 LSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSL------- 1519
L++A E+ + E++ R K ++++ L E +L+ +LE+ +D Q++ S
Sbjct: 1145 LAEAQEDLESERVARTKAEKQRRDLGEELEALRGELED-TLDSTNAQQELRSKREQEVTE 1203
Query: 1520 ------------EAELQDISSQESKDEASLAKVKKQLR-----------DLEAKVKDQEE 1556
EA +Q++ + + LA+ +Q R LEA+V +
Sbjct: 1204 LKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRA 1263
Query: 1557 ELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLE 1616
EL Q EQ + RLE++++ E++ R + E AR +KL++ + +LE
Sbjct: 1264 ELSSLQTARQEGEQRRRRLELQLQ--------EVQGRAGDGERARAEAAEKLQRAQAELE 1315
Query: 1617 EE----YEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLML 1672
E + K +R +EL A L D E+ +L R +A+ A+A +
Sbjct: 1316 NVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALG-SRVRAMEAEAAGLR 1374
Query: 1673 DHLKNSAPSKR-----------EIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQID 1721
+ L+ A ++ ++++ + + EE A +AR+ E E L ++
Sbjct: 1375 EQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLA 1434
Query: 1722 DIAKAKTALEEQLSRLQRE----------KNEIQNRLEEDQEDMNELMKKHKAAVAQASR 1771
+ + LE RLQ+E + ++ + LE+ Q ++L+ + KAAV +A
Sbjct: 1435 EKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVE 1494
Query: 1772 DL-----------AQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSM--VDKSL-- 1816
+ A+ L LEE + ++EL+ + +AL++++E L S V KS+
Sbjct: 1495 ERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHE 1554
Query: 1817 ------VSRQ-----EAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAA 1865
V+ Q A++ ELE L RLE LK E+ + RD+
Sbjct: 1555 LERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDE---- 1610
Query: 1866 ENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLA 1925
+E+ ++L +QLRD + E E ++ A + +LE +LE L+A S + A
Sbjct: 1611 --AGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEA 1668
Query: 1926 FKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKS 1970
K++ +QA ++ E+ + E + E + E E R+ G+++
Sbjct: 1669 VKQLRKMQAQMK-ELWREVEETRTSREEIFSQNRESEKRLKGLEA 1712
Score = 192 bits (489), Expect = 2e-48
Identities = 169/696 (24%), Positives = 332/696 (47%), Gaps = 49/696 (7%)
Query: 1244 RPLIEVQLSEEQIRNKDEEIQQLRS--KLEKAEKERNELRLNSDRLESRISELTSELTDE 1301
R +E+QL E Q R D E + + KL++A+ E + + ES+ L+ EL+
Sbjct: 1279 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1338
Query: 1302 RNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
A +LL ET +L ++ ++ + L++Q+E
Sbjct: 1339 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE-------------------- 1378
Query: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEE 1420
++A R E + ++ R +QE E LE ++ +R+ R L E
Sbjct: 1379 ---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1435
Query: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480
+ +L++ +RL EL D + LE Q+ LEKKQR+FD L++ R +
Sbjct: 1436 KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1495
Query: 1481 REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKV 1540
RE+ + E A A SL + LEE+ ++ +L AEL+ + S + S+ ++
Sbjct: 1496 RERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1555
Query: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600
++ R E D ++ E + E AKLRLE+ ++ ++ H ++++ RDE EE
Sbjct: 1556 ERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1615
Query: 1601 RQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKD 1657
R+ K+L+ EV+ +EE + + + +++LEG+L L Q+ + E+ K+LRK
Sbjct: 1616 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1675
Query: 1658 LKRTKALLADAQLML----DHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEI 1713
+ K L + + + + S++ + L+ ++ + AA+ +AR+ + +
Sbjct: 1676 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDR 1735
Query: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773
+++ ++ + +K A+ E+ +L+ +++ LEE+Q + L +++ + Q
Sbjct: 1736 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLT 1795
Query: 1774 AQINDLQAQLEEANKEKQELQEKLQALQSQV--EFLEQSMVDKSLVSRQEAKIRELETRL 1831
+++ ++ +A +Q+L+ ++Q L+ ++ E K ++ E+K+ + E +L
Sbjct: 1796 TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQL 1855
Query: 1832 EFERTQV----KRLESLASRLKENMEKLTEERDQRIAAENREKEQN-----KRLQRQLRD 1882
E E + K + RLKE + ++ EER R+A + R++ + K+L+RQL +
Sbjct: 1856 EQETRERILSGKLVRRAEKRLKEVVLQVEEER--RVADQLRDQLEKGNLRVKQLKRQLEE 1913
Query: 1883 TKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918
+E E +R +A R + ELE ES E+ N+ +
Sbjct: 1914 AEE---EASRAQAGRRRLQRELEDVTESAESMNREV 1946
Score = 156 bits (394), Expect = 2e-37
Identities = 158/747 (21%), Positives = 329/747 (44%), Gaps = 116/747 (15%)
Query: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
+EQ+ + + ++LR++L + E+E ++ ++L L + + A + L
Sbjct: 1093 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1152
Query: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
++E R +AEK+ ++L + +AL+ ++E +D +A E R
Sbjct: 1153 ESERVARTKAEKQRRDLGEELEALRGELE------------------DTLDSTNAQQELR 1194
Query: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
K E+ V E+ KK L++E Q+ +++ + LG+L E+++R +K
Sbjct: 1195 SKREQEVTEL---KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1251
Query: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA---------QREKLQRE- 1482
L AE+ + + L Q E E+++RR + +L + A EKLQR
Sbjct: 1252 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1311
Query: 1483 ------------------KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524
+L +E A+ ++ L+E+ +V ++EAE
Sbjct: 1312 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1371
Query: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQ 1584
+ Q ++ A+ + ++L+ +A++ + +E+AG ++ E+A+ R E E + Q
Sbjct: 1372 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1431
Query: 1585 THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY------------------EDKQKVL 1626
+++ E+ D +E R+ Q++L + LE++ E+K VL
Sbjct: 1432 RLAEKTETVDR-LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1490
Query: 1627 R-----EKRELEGKLATLSDQVNRRDFESEKRLRKDLKR-TKALLADAQLMLDHLKNSAP 1680
R E+ E EG+ R E E+ R++L+R +AL A+ + +L
Sbjct: 1491 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS------- 1543
Query: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740
SK ++ + ++LE +A + E DL Q+ ++ TA E+ RL+
Sbjct: 1544 SKDDVGKSVHELE----------RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVT 1593
Query: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800
++ + E D + +E ++ + +A+ Q+ D + + +E K++ + L
Sbjct: 1594 VQALKTQHERDLQGRDEAGEERRRQLAK------QLRDAEVERDEERKQRTLAVAARKKL 1647
Query: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860
+ ++E L+ M ++EA VK+L + +++KE ++ E R
Sbjct: 1648 EGELEELKAQMASAGQ-GKEEA---------------VKQLRKMQAQMKELWREVEETRT 1691
Query: 1861 QR--IAAENREKEQN-KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917
R I ++NRE E+ K L+ ++ +EE+ R +A + + E+ ++ + + +
Sbjct: 1692 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1751
Query: 1918 LQADLKLAFKRIGDLQAAIEDEMESDE 1944
+ + + R+G L+ +E+E + E
Sbjct: 1752 ILEEKRQLEGRLGQLEEELEEEQSNSE 1778
Score = 116 bits (291), Expect = 2e-25
Identities = 115/507 (22%), Positives = 228/507 (44%), Gaps = 38/507 (7%)
Query: 1249 VQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESA 1308
V E++ R D+ + + ++ + +A +ER E+R LT L +E+ E
Sbjct: 1468 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1527
Query: 1309 SQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368
+ A AE ++ L++ V E + R A++ D+ A
Sbjct: 1528 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR----AQVTELEDELTAA 1583
Query: 1369 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD--LQADSEESQRALQ 1426
+ +L+ E V+ + K + +++ + + E ++ +RQL ++L D ++ D E QR L
Sbjct: 1584 EDAKLRLEVTVQAL---KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1640
Query: 1427 QLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKL-- 1484
+K +L EL++ K + E K+ R+ +++ + E + + RE++
Sbjct: 1641 VAARK--KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFS 1698
Query: 1485 -QREKDMLL----AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539
RE + L AE L+++L D + + + +++ + + S A
Sbjct: 1699 QNRESEKRLKGLEAEVLRLQEELAASD-------RARRQAQQDRDEMADEVANGNLSKAA 1751
Query: 1540 VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599
+ ++ R LE ++ EEEL+E+ ++L +L +++E + S E S + E
Sbjct: 1752 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE-RSFSAKAES 1810
Query: 1600 ARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE---LEGKLATLSDQVNRRDFE---SEKR 1653
RQ +++++++ +L EE D R K LE KLA +Q+ + E S K
Sbjct: 1811 GRQQLERQIQELRGRLGEE--DAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1868
Query: 1654 LRKDLKRTKALLADAQ---LMLDHLKNSAPSKR-EIAQLKNQLEESEFTCAAAVKARKAM 1709
+R+ KR K ++ + + D L++ + QLK QLEE+E + A R+ +
Sbjct: 1869 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1928
Query: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSR 1736
+ E+ED+ + + + T L +L R
Sbjct: 1929 QRELEDVTESAESMNREVTTLRNRLRR 1955
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 527 bits (1357), Expect = e-149
Identities = 482/1811 (26%), Positives = 838/1811 (46%), Gaps = 301/1811 (16%)
Query: 346 WNETEKVWLVHR-DGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSC 404
W VW+ GF A+ L+ E E + V+L G L + D +++ N P
Sbjct: 50 WTARRLVWVPSELHGFEAAA-LRDEG----EEEAEVELAESGRRLRLPRDQIQRMNPPKF 104
Query: 405 DRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKG 464
+ ED+A L LNE+SVLH LR+RY + L++TY+G +V+ P +Y+E ++ M++G
Sbjct: 105 SKAEDMAELTCLNEASVLHNLRERYYSGLIYTYSGLFCVVINPYKQLPIYTEAIVEMYRG 164
Query: 465 CRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI-SG 523
+R ++ PH+YAV + AYR+ML R+DQSI+ G SG+GKT + + ++QYLA +A G
Sbjct: 165 KKRHEVPPHVYAVTEGAYRSMLQDREDQSILCTGESGAGKTENTKKVIQYLAHVASSPKG 224
Query: 524 NKVFSVEKWQALYT-------------LLEAFGNSPTIINGNATRFSQILSLDFDQAGQV 570
K V + + +LEAFGN+ T+ N N++RF + + ++FD AG +
Sbjct: 225 RKEPGVPASVSTVSYGELERQLLQANPILEAFGNAKTVKNDNSSRFGKFIRINFDVAGYI 284
Query: 571 ASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLA 630
A+I+T LLEK R R+ E +F++FY LL L+ +L L + P +
Sbjct: 285 VGANIETYLLEKSRAIRQAKDECSFHIFYQLLGGAGEQLKADLLLEPCSHYRFLTNGPSS 344
Query: 631 KPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFA 690
P ++++ F + +++VLG S +E + +++A+ G A K +
Sbjct: 345 SPGQEREL---FQETLESLRVLGFSHEEIISMLRMVSAVLQFGNI-ALKRERNTDQATMP 400
Query: 691 RHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSA 748
+ AQK LLG + + S A+ + K G +Q++ + Q A
Sbjct: 401 DNTAAQKLCRLLGLGVTDFSRALLTPRIKVGRDYVQKAQTKEQ----------------A 444
Query: 749 LECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMM-IVDTPGFQNPEQGGSARGASF 807
LE +A Y LF LV +NRAL S S + I+D GF+ + SF
Sbjct: 445 DFALEALAKATYERLFRWLVLRLNRALDRSPRQGASFLGILDIAGFEIFQLN------SF 498
Query: 808 EELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLV 867
E+LC NYT ++LQ+LF+ FV E E Y+ E I F D + +++ ++
Sbjct: 499 EQLCINYTNEKLQQLFNHTMFVLEQEEYQREGIPWTFLDFGLDLQPCIDLIERPANPP-- 556
Query: 868 RSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHF 927
GLL LL+EE P A++ + +E++ G G K Q P H F
Sbjct: 557 ----------GLLALLDEECWFPKATDKSFVEKVAQEQG---GHPKFQRPR-HLRDQADF 602
Query: 928 LLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNL------------FL 975
+ H G V+Y WL +P N LL S ++ + + FL
Sbjct: 603 SVLHYAGK--VDYKANEWL-MKNMDPLNDNVAALLHQSTDRLTAEIWKDEHGGFQQFSFL 659
Query: 976 GR-----AGSATVLSGSIA--GLEGGSQLALRRATSM---------RKTFTTGMAAVKKK 1019
G GSA S +I+ G+EG + L + +S+ R+ + + K+
Sbjct: 660 GSFPPSPPGSAERCSSAISPPGVEG--IVGLEQVSSLGDGPPGGRPRRGMFRTVGQLYKE 717
Query: 1020 SLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDH 1079
SL L+ T+ + FV C +P E AG+
Sbjct: 718 SL--------SRLMATLSNTNPSFVRCIVPNHEKRAGK---------------------- 747
Query: 1080 CEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRN 1139
L+ L+ QLR + +L+ +R+ RQG+P+ ++F EFR+R+++L P+ K
Sbjct: 748 -------LEPRLVLDQLRCNGVLEGIRICRQGFPNRILFQEFRQRYEILTPNAIPKG--- 797
Query: 1140 YIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAAC 1199
+D ++A E++++ L+L+ + +G S++FFRAG LA+LEE+RD + + + FQAA
Sbjct: 798 --FMDGKQACEKMIQALELDPNLYRVGQSKIFFRAGVLAQLEEERDLKVTDIIVSFQAAA 855
Query: 1200 RGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNK 1259
RGYLAR+ F+KR+ Q A+R +Q+N ++ W WW+LFT V+PL++V +E ++ +
Sbjct: 856 RGYLARRAFQKRQQQQSALRVMQRNCAAYLKLRHWQWWRLFTKVKPLLQVTRQDEVLQAR 915
Query: 1260 DEEIQ--------------------------------QLRSKLE---KAEKERNELRLNS 1284
+E+Q QLR++ E +AE+ R L
Sbjct: 916 AQELQKVQELQQQSAREVGELQGRVAQLEEERARLAEQLRAEAELCAEAEETRGRLAARK 975
Query: 1285 DRLESRISELTSELTDERNTGESAS----------QLLDA--ETAERLRAEKEMKELQTQ 1332
LE +SEL + + +E Q L+A E E R + +++++ T+
Sbjct: 976 QELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTE 1035
Query: 1333 YDALKKQMEVMEMEVMEARLI--------RAAEINGEVDDDD----AGGEWRLKYERAVR 1380
K + +++ +E ++L R AE + + +++ + + RLKYE +
Sbjct: 1036 AKMKKFEEDLLLLEDQNSKLSKERKLLEDRLAEFSSQAAEEEEKVKSLNKLRLKYEATIA 1095
Query: 1381 EVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQ 1440
+++ RL++E + + E+E+ KR+L+ +LQ E Q+ ++L+ + R ELQ
Sbjct: 1096 DME---DRLRKEEKGRQELEKL-KRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQ 1151
Query: 1441 DTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQ 1500
E + +L K R + L++A E+ + E++ R K ++++ L E +L+
Sbjct: 1152 AALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRG 1211
Query: 1501 QLEEKDMDIAGFTQKVVSL-------------------EAELQDISSQESKDEASLAKVK 1541
+LE+ +D Q++ S EA +Q++ + + LA+
Sbjct: 1212 ELED-TLDSTNAQQELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQL 1270
Query: 1542 KQLR-----------DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEM 1590
+Q R LEA+V + EL Q EQ + RLE++++ E+
Sbjct: 1271 EQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQ--------EV 1322
Query: 1591 ESRDEEVEEARQSCQKKLKQMEVQLEEE----YEDKQKVLREKRELEGKLATLSDQVNRR 1646
+ R + E AR +KL++ + +LE E + K +R +EL A L D
Sbjct: 1323 QGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELL 1382
Query: 1647 DFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKR-----------EIAQLKNQLEES 1695
E+ +L R +A+ A+A + + L+ A ++ ++++ + + EE
Sbjct: 1383 QEETRAKLALG-SRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEE 1441
Query: 1696 EFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE----------KNEIQ 1745
A +AR+ E E L ++ + + LE RLQ+E + ++
Sbjct: 1442 AGALEAGEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLV 1501
Query: 1746 NRLEEDQEDMNELMKKHKAAVAQASRDL-----------AQINDLQAQLEEANKEKQELQ 1794
+ LE+ Q ++L+ + KAAV +A + A+ L LEE + ++EL+
Sbjct: 1502 STLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELE 1561
Query: 1795 EKLQALQSQVEFLEQSM--VDKSL--------VSRQ-----EAKIRELETRLEFERTQVK 1839
+ +AL++++E L S V KS+ V+ Q A++ ELE L
Sbjct: 1562 RQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKL 1621
Query: 1840 RLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASR 1899
RLE LK E+ + RD+ +E+ ++L +QLRD + E E ++ A
Sbjct: 1622 RLEVTVQALKTQHERDLQGRDE------AGEERRRQLAKQLRDAEVERDEERKQRTLAVA 1675
Query: 1900 KKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDS 1959
+ +LE +LE L+A S + A K++ +QA ++ E+ + E + E +
Sbjct: 1676 ARKKLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMK-ELWREVEETRTSREEIFSQNR 1734
Query: 1960 ELEDRVDGVKS 1970
E E R+ G+++
Sbjct: 1735 ESEKRLKGLEA 1745
Score = 192 bits (489), Expect = 2e-48
Identities = 169/696 (24%), Positives = 332/696 (47%), Gaps = 49/696 (7%)
Query: 1244 RPLIEVQLSEEQIRNKDEEIQQLRS--KLEKAEKERNELRLNSDRLESRISELTSELTDE 1301
R +E+QL E Q R D E + + KL++A+ E + + ES+ L+ EL+
Sbjct: 1312 RRRLELQLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSST 1371
Query: 1302 RNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
A +LL ET +L ++ ++ + L++Q+E
Sbjct: 1372 EAQLHDAQELLQEETRAKLALGSRVRAMEAEAAGLREQLE-------------------- 1411
Query: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE-DKLEVEQQNKRQLERRLGDLQADSEE 1420
++A R E + ++ R +QE E LE ++ +R+ R L E
Sbjct: 1412 ---EEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQRLAE 1468
Query: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480
+ +L++ +RL EL D + LE Q+ LEKKQR+FD L++ R +
Sbjct: 1469 KTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEE 1528
Query: 1481 REKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKV 1540
RE+ + E A A SL + LEE+ ++ +L AEL+ + S + S+ ++
Sbjct: 1529 RERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHEL 1588
Query: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600
++ R E D ++ E + E AKLRLE+ ++ ++ H ++++ RDE EE
Sbjct: 1589 ERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEER 1648
Query: 1601 RQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKD 1657
R+ K+L+ EV+ +EE + + + +++LEG+L L Q+ + E+ K+LRK
Sbjct: 1649 RRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEEAVKQLRKM 1708
Query: 1658 LKRTKALLADAQLML----DHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEI 1713
+ K L + + + + S++ + L+ ++ + AA+ +AR+ + +
Sbjct: 1709 QAQMKELWREVEETRTSREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDR 1768
Query: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDL 1773
+++ ++ + +K A+ E+ +L+ +++ LEE+Q + L +++ + Q
Sbjct: 1769 DEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLT 1828
Query: 1774 AQINDLQAQLEEANKEKQELQEKLQALQSQV--EFLEQSMVDKSLVSRQEAKIRELETRL 1831
+++ ++ +A +Q+L+ ++Q L+ ++ E K ++ E+K+ + E +L
Sbjct: 1829 TELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAALESKLAQAEEQL 1888
Query: 1832 EFERTQV----KRLESLASRLKENMEKLTEERDQRIAAENREKEQN-----KRLQRQLRD 1882
E E + K + RLKE + ++ EER R+A + R++ + K+L+RQL +
Sbjct: 1889 EQETRERILSGKLVRRAEKRLKEVVLQVEEER--RVADQLRDQLEKGNLRVKQLKRQLEE 1946
Query: 1883 TKEEMGELARKEAEASRKKHELEMDLESLEAANQSL 1918
+E E +R +A R + ELE ES E+ N+ +
Sbjct: 1947 AEE---EASRAQAGRRRLQRELEDVTESAESMNREV 1979
Score = 156 bits (394), Expect = 2e-37
Identities = 158/747 (21%), Positives = 329/747 (44%), Gaps = 116/747 (15%)
Query: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
+EQ+ + + ++LR++L + E+E ++ ++L L + + A + L
Sbjct: 1126 QEQMVEQQQRAEELRAQLGRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDL 1185
Query: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
++E R +AEK+ ++L + +AL+ ++E +D +A E R
Sbjct: 1186 ESERVARTKAEKQRRDLGEELEALRGELE------------------DTLDSTNAQQELR 1227
Query: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
K E+ V E+ KK L++E Q+ +++ + LG+L E+++R +K
Sbjct: 1228 SKREQEVTEL---KKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1284
Query: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA---------QREKLQRE- 1482
L AE+ + + L Q E E+++RR + +L + A EKLQR
Sbjct: 1285 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1344
Query: 1483 ------------------KLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQ 1524
+L +E A+ ++ L+E+ +V ++EAE
Sbjct: 1345 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1404
Query: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQ 1584
+ Q ++ A+ + ++L+ +A++ + +E+AG ++ E+A+ R E E + Q
Sbjct: 1405 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGEEARRRAAREAEALTQ 1464
Query: 1585 THSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY------------------EDKQKVL 1626
+++ E+ D +E R+ Q++L + LE++ E+K VL
Sbjct: 1465 RLAEKTETVDR-LERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVL 1523
Query: 1627 R-----EKRELEGKLATLSDQVNRRDFESEKRLRKDLKR-TKALLADAQLMLDHLKNSAP 1680
R E+ E EG+ R E E+ R++L+R +AL A+ + +L
Sbjct: 1524 RAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEALLS------- 1576
Query: 1681 SKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE 1740
SK ++ + ++LE +A + E DL Q+ ++ TA E+ RL+
Sbjct: 1577 SKDDVGKSVHELE----------RACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVT 1626
Query: 1741 KNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQAL 1800
++ + E D + +E ++ + +A+ Q+ D + + +E K++ + L
Sbjct: 1627 VQALKTQHERDLQGRDEAGEERRRQLAK------QLRDAEVERDEERKQRTLAVAARKKL 1680
Query: 1801 QSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERD 1860
+ ++E L+ M ++EA VK+L + +++KE ++ E R
Sbjct: 1681 EGELEELKAQMASAGQ-GKEEA---------------VKQLRKMQAQMKELWREVEETRT 1724
Query: 1861 QR--IAAENREKEQN-KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQS 1917
R I ++NRE E+ K L+ ++ +EE+ R +A + + E+ ++ + + +
Sbjct: 1725 SREEIFSQNRESEKRLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAA 1784
Query: 1918 LQADLKLAFKRIGDLQAAIEDEMESDE 1944
+ + + R+G L+ +E+E + E
Sbjct: 1785 ILEEKRQLEGRLGQLEEELEEEQSNSE 1811
Score = 116 bits (291), Expect = 2e-25
Identities = 115/507 (22%), Positives = 228/507 (44%), Gaps = 38/507 (7%)
Query: 1249 VQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESA 1308
V E++ R D+ + + ++ + +A +ER E+R LT L +E+ E
Sbjct: 1501 VSTLEKKQRKFDQLLAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREEL 1560
Query: 1309 SQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368
+ A AE ++ L++ V E + R A++ D+ A
Sbjct: 1561 ERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLR----AQVTELEDELTAA 1616
Query: 1369 GEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD--LQADSEESQRALQ 1426
+ +L+ E V+ + K + +++ + + E ++ +RQL ++L D ++ D E QR L
Sbjct: 1617 EDAKLRLEVTVQAL---KTQHERDLQGRDEAGEERRRQLAKQLRDAEVERDEERKQRTLA 1673
Query: 1427 QLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKL-- 1484
+K +L EL++ K + E K+ R+ +++ + E + + RE++
Sbjct: 1674 VAARK--KLEGELEELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFS 1731
Query: 1485 -QREKDMLL----AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539
RE + L AE L+++L D + + + +++ + + S A
Sbjct: 1732 QNRESEKRLKGLEAEVLRLQEELAASD-------RARRQAQQDRDEMADEVANGNLSKAA 1784
Query: 1540 VKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599
+ ++ R LE ++ EEEL+E+ ++L +L +++E + S E S + E
Sbjct: 1785 ILEEKRQLEGRLGQLEEELEEEQSNSELLNDRYRKLLLQVESLTTELSAE-RSFSAKAES 1843
Query: 1600 ARQSCQKKLKQMEVQLEEEYEDKQKVLREKRE---LEGKLATLSDQVNRRDFE---SEKR 1653
RQ +++++++ +L EE D R K LE KLA +Q+ + E S K
Sbjct: 1844 GRQQLERQIQELRGRLGEE--DAGARARHKMTIAALESKLAQAEEQLEQETRERILSGKL 1901
Query: 1654 LRKDLKRTKALLADAQ---LMLDHLKNSAPSKR-EIAQLKNQLEESEFTCAAAVKARKAM 1709
+R+ KR K ++ + + D L++ + QLK QLEE+E + A R+ +
Sbjct: 1902 VRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQLKRQLEEAEEEASRAQAGRRRL 1961
Query: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSR 1736
+ E+ED+ + + + T L +L R
Sbjct: 1962 QRELEDVTESAESMNREVTTLRNRLRR 1988
>gi|115496169 myosin, heavy chain 7, cardiac muscle, beta [Homo
sapiens]
Length = 1935
Score = 515 bits (1326), Expect = e-145
Identities = 420/1668 (25%), Positives = 796/1668 (47%), Gaps = 219/1668 (13%)
Query: 366 LKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTL 425
+K++ ++ GKV + ++ G + V ED V + N P D++ED+A L +L+E +VL+ L
Sbjct: 47 VKAKIVSREGGKVTAETEY-GKTVTVKEDQVMQQNPPKFDKIEDMAMLTFLHEPAVLYNL 105
Query: 426 RQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAM 485
+ RYG+ +++TY+G + + P VY+ +V+ ++G +R + PHI++++ AY+ M
Sbjct: 106 KDRYGSWMIYTYSGLFCVTVNPYKWLPVYTPEVVAAYRGKKRSEAPPHIFSISDNAYQYM 165
Query: 486 LMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI--------SGNKVFSVEKWQALYT 537
L R++QSI++ G SG+GKT + + ++QY A IA I S K ++
Sbjct: 166 LTDRENQSILITGESGAGKTVNTKRVIQYFAVIAAIGDRSKKDQSPGKGTLEDQIIQANP 225
Query: 538 LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNV 597
LEAFGN+ T+ N N++RF + + + F G++ASA I+T LLEK RV + +E +++
Sbjct: 226 ALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERDYHI 285
Query: 598 FYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGI 654
FY +L+ + EL L NN + +++ E + +L A A VLG
Sbjct: 286 FYQILS----NKKPELLDMLLITNNPYDYAFISQGETTVASIDDAEELMATDNAFDVLGF 341
Query: 655 SPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIF 714
+ +E+ + + + AI H G + E + E A K+AYL+G + +L +
Sbjct: 342 TSEEKNSMYKLTGAIMHFGNMKFKLKQREEQAEPDGTEE-ADKSAYLMGLNSADLLKGLC 400
Query: 715 KHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRA 774
+ K G + +G + TG +A +Y +F +V+ +N
Sbjct: 401 HPRVKVG----NEYVTKGQNVQQVIYATG----------ALAKAVYERMFNWMVTRINAT 446
Query: 775 LKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELER 834
L++ Q + ++D GF+ + SFE+LC N+T ++LQ+ F+ FV E E
Sbjct: 447 LETKQPRQYFIGVLDIAGFEIFDFN------SFEQLCINFTNEKLQQFFNHHMFVLEQEE 500
Query: 835 YKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASE 894
YK+E IE F D D A +D ++ G++ +LEEE + P A++
Sbjct: 501 YKKEGIEWTFIDFGM---DLQACID------------LIEKPMGIMSILEEECMFPKATD 545
Query: 895 DTLLERLFSYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNP 953
T +LF + + + Q P KP HF L H G V+YN+ GWL K +P
Sbjct: 546 MTFKAKLFDNHLGKSAN--FQKPRNIKGKPEAHFSLIHYAGI--VDYNIIGWLQKNK-DP 600
Query: 954 ATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGM 1013
+ L Q S K++S LF AG+ + + GS +F T +
Sbjct: 601 LNETVVGLYQKSSLKLLSTLFANYAGADAPIEKGKGKAKKGS------------SFQT-V 647
Query: 1014 AAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELD 1073
+A+ +++L + L+ ++ + HFV C +P E +S
Sbjct: 648 SALHRENL--------NKLMTNLRSTHPHFVRCIIP------NETKSPG----------- 682
Query: 1074 LPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLT 1133
+D PL+ QLR + +L+ +R+ R+G+P+ +++ +FR+R+ +L P
Sbjct: 683 ------------VMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILNPAAI 730
Query: 1134 KKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLT 1193
+ +D R+ E+LL LD++ + G ++VFF+AG L LEE RDE+ SR +T
Sbjct: 731 PEGQ----FIDSRKGAEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLSRIIT 786
Query: 1194 LFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSE 1253
QA RG LAR +KK + ++ +Q NI+ GVK+WPW KL+ ++PL++ E
Sbjct: 787 RIQAQSRGVLARMEYKKLLERRDSLLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKSAERE 846
Query: 1254 EQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLD 1313
+++ + EE +L+ LEK+E R EL L ++L ++ E++ A + D
Sbjct: 847 KEMASMKEEFTRLKEALEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLADAEERCD 906
Query: 1314 AETAERLRAEKEMKELQTQYDALKKQMEV-MEMEVMEARL-IRAAEINGEVDDDDAGGEW 1371
+++ E ++KE+ + L+ + E+ E+ + +L +E+ ++DD
Sbjct: 907 QLIKNKIQLEAKVKEMN---ERLEDEEEMNAELTAKKRKLEDECSELKRDIDD------L 957
Query: 1372 RLKYERAVREVDFTKKRLQQEFEDKLEVEQ------QNKRQL----ERRLGDLQADSEES 1421
L + +E T+ +++ E+ +++ + K+ L ++ L DLQA+ ++
Sbjct: 958 ELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQAEEDK- 1016
Query: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREK 1478
+ L K +L ++ D + LE ++ +LE+ +R+ + +L E + + +K
Sbjct: 1017 ---VNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLENDK 1073
Query: 1479 LQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLA 1538
Q ++ ++KD E +L ++E++ + +K+ L+A ++++ + + + A
Sbjct: 1074 QQLDERLKKKDF---ELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARA 1130
Query: 1539 KVKKQLRDLEAKVKDQEEELDEQAGTIQM------------------LEQAKLRLEMEME 1580
KV+K DL ++++ E L+E G + LE+A L+ E
Sbjct: 1131 KVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAA 1190
Query: 1581 RMRQTHSKEMESRDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLA 1637
+R+ H+ + E++ + +Q +K+ + +++L++ + +++++ K LE
Sbjct: 1191 ALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCR 1250
Query: 1638 TLSDQVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEF 1697
TL DQ+N ++E+ R + D A + E +L QL+E E
Sbjct: 1251 TLEDQMNEHRSKAEETQRS--------------VNDLTSQRAKLQTENGELSRQLDEKEA 1296
Query: 1698 TCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQE---D 1754
+ + + ++EDL Q+++ KAK AL L + + + ++ + EE+ E +
Sbjct: 1297 LISQLTRGKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAE 1356
Query: 1755 MNELMKKHKAAVAQ------------------ASRDLAQ-INDLQAQLEEANKEKQELQE 1795
+ ++ K + VAQ A + LAQ + + + +E N + L++
Sbjct: 1357 LQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEK 1416
Query: 1796 KLQALQSQVEFL----EQSMVDKSLVSRQEAK----IRELETRLEFERTQVKRLESLASR 1847
LQ+++E L E+S + + +++ + E + + E +++++ + A
Sbjct: 1417 TKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARS 1476
Query: 1848 LKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMG---------ELARKEAEAS 1898
L + KL ++ + K +NK LQ ++ D E++G E RK+ EA
Sbjct: 1477 LSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEA- 1535
Query: 1899 RKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENE 1946
+K EL+ LE EA+ + + + A ++A IE ++ + E
Sbjct: 1536 -EKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEE 1582
Score = 193 bits (490), Expect = 2e-48
Identities = 177/797 (22%), Positives = 373/797 (46%), Gaps = 39/797 (4%)
Query: 1144 DERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYL 1203
D R +EE+ E LE++ G + V E Q+ + TL A L
Sbjct: 1138 DLSRELEEISE--RLEEAG---GATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAAL 1192
Query: 1204 ARQHFKKRKIQDLA-----IRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLS-EEQIR 1257
++H + +L ++ V++ ++K K + + + +I+ + + E+ R
Sbjct: 1193 RKKHADS--VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKMCR 1250
Query: 1258 NKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETA 1317
++++ + RSK E+ ++ N+L +L++ EL+ +L DE+ L+ T
Sbjct: 1251 TLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQL-DEKEA------LISQLTR 1303
Query: 1318 ERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYER 1377
+L +++++L+ Q + K + + AR ++ +A E + +
Sbjct: 1304 GKLTYTQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSK 1363
Query: 1378 AVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTA 1437
A EV + + + + + E ++ K++L +RL + + E L+K RL
Sbjct: 1364 ANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQN 1423
Query: 1438 ELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1497
E++D + +E L+KKQR FD L++ ++ + + + E Q+E L E F
Sbjct: 1424 EIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK 1483
Query: 1498 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1557
LK EE + F ++ +L+ E+ D++ Q ++ +++K + LEA+ + +
Sbjct: 1484 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSA 1543
Query: 1558 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1617
L+E +++ E LR ++E +++ +++ +DEE+E+A+++ + + ++ L+
Sbjct: 1544 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHLRVVDSLQTSLDA 1603
Query: 1618 EYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKR---LRKDLKRTKALLADAQLM 1671
E + + LR K+++EG L + Q+ NR E++K+ L+ LK T+ L DA
Sbjct: 1604 ETRSRNEALRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1663
Query: 1672 LDHLK-NSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTAL 1730
D LK N A +R L+ +LEE ++RK E E+ + ++ + T+L
Sbjct: 1664 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1723
Query: 1731 EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQA---SRDLAQINDLQAQLEEAN 1787
Q ++ + +++Q +EE ++ +K K A+ A + +L + D A LE
Sbjct: 1724 INQKKKMDADLSQLQTEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE--- 1780
Query: 1788 KEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELETRLEFERTQ----VKRL 1841
+ K+ +++ ++ LQ +++ EQ + K + + EA++RELE LE E+ + VK +
Sbjct: 1781 RMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGM 1840
Query: 1842 ESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901
R+KE + E+R + ++ + +++ R +E + ++ + +
Sbjct: 1841 RKSERRIKELTYQTEEDRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQ 1900
Query: 1902 HELEMDLESLEAANQSL 1918
HEL+ E + A +
Sbjct: 1901 HELDEAEERADIAESQV 1917
Score = 169 bits (428), Expect = 3e-41
Identities = 196/849 (23%), Positives = 392/849 (46%), Gaps = 87/849 (10%)
Query: 1176 TLARLEEQRD--EQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKD 1233
TLA++E+++ E +NLT A +A+ +K+ +Q+ Q+ + + +D
Sbjct: 960 TLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAH----QQALDDLQAEED 1015
Query: 1234 WPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKE-RNELRLNSDR---LES 1289
K+ T + ++++ + + E+ +++R LE+A+++ +L+L + LE+
Sbjct: 1016 ----KVNTLTKAKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIMDLEN 1071
Query: 1290 RISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVME 1349
+L L + + + ++ E A + +K++KELQ + + L++++E +
Sbjct: 1072 DKQQLDERLKKKDFELNALNARIEDEQALGSQLQKKLKELQARIEELEEELEAERTARAK 1131
Query: 1350 ARLIRAAEINGEVDD-----DDAGGEWRLKYE-RAVREVDFTKKRLQQEFEDKLEVEQQN 1403
+R+ +++ E+++ ++AGG ++ E RE +F K R ++ E+ +
Sbjct: 1132 VEKLRS-DLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMR--RDLEEATLQHEAT 1188
Query: 1404 KRQLERRLGDLQADSEES----QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKK 1459
L ++ D A+ E QR Q+L+K+ EL D ++E LEK
Sbjct: 1189 AAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKM 1248
Query: 1460 QRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSL 1519
R + ++++ +A+ + L ++ L E L +QL+EK+ I+ T+ ++
Sbjct: 1249 CRTLEDQMNEHRSKAEETQRSVNDLTSQRAKLQTENGELSRQLDEKEALISQLTRGKLTY 1308
Query: 1520 EAELQDISSQ---ESKDEASLAKVKKQLR-DLEAKVKDQEEELDEQAGTIQMLEQAKLRL 1575
+L+D+ Q E K + +LA + R D + + EEE + +A ++L +A
Sbjct: 1309 TQQLEDLKRQLEEEVKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSKAN--- 1365
Query: 1576 EMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGK 1635
E+ + R + + R EE+EEA++ ++L++ E +E + + K L+ +
Sbjct: 1366 -SEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEAVEAVNAKCSSLEKTKHRLQNE 1424
Query: 1636 LATLSDQVNRRDF------ESEKRLRKDLKRTKALLADAQLMLDHLKNSAPS-KREIAQL 1688
+ L V R + + ++ K L K ++Q L+ + A S E+ +L
Sbjct: 1425 IEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFKL 1484
Query: 1689 KNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRL 1748
KN EES + K ++ EI DL Q+ K LE+ +L+ EK E+Q+ L
Sbjct: 1485 KNAYEESLEHLETFKRENKNLQEEISDLTEQLGSSGKTIHELEKVRKQLEAEKMELQSAL 1544
Query: 1749 EEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLE 1808
EE A+AS + + L+AQLE N+ K E++ KL ++E +
Sbjct: 1545 EE----------------AEASLEHEEGKILRAQLE-FNQIKAEIERKLAEKDEEMEQAK 1587
Query: 1809 QSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENR 1868
++ + + L+T L+ E R + A R+K+ ME E + +++ NR
Sbjct: 1588 RNHL---------RVVDSLQTSLDAET----RSRNEALRVKKKMEGDLNEMEIQLSHANR 1634
Query: 1869 ----EKEQNKRLQRQLRDTKEEMGELARKE-------AEASRKKHELEMDLESLEAANQS 1917
++Q K LQ L+DT+ ++ + R A R+ + L+ +LE L A +
Sbjct: 1635 MAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVVEQ 1694
Query: 1918 LQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD-SELEDRV-DGVKSWLSKN 1975
+ KLA + + ++ + ++ +N LIN + D D S+L+ V + V+ +
Sbjct: 1695 TERSRKLAEQEL--IETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 1752
Query: 1976 KGPSKAASD 1984
+ KA +D
Sbjct: 1753 EKAKKAITD 1761
Score = 118 bits (296), Expect = 5e-26
Identities = 131/594 (22%), Positives = 267/594 (44%), Gaps = 68/594 (11%)
Query: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGES 1307
+ L EQ + E +L+ L KA E + R + E+ + T EL + + +
Sbjct: 1339 DCDLLREQYEEETEAKAELQRVLSKANSEVAQWRT---KYETDAIQRTEELEEAKK--KL 1393
Query: 1308 ASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDA 1367
A +L +AE A + L+ L+ ++E + ++V + AA + + D
Sbjct: 1394 AQRLQEAEEAVEA-VNAKCSSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKI 1452
Query: 1368 GGEWRLKYERAVREVDFTKK----------RLQQEFEDKLEVEQQNKRQ---LERRLGDL 1414
EW+ KYE + E++ ++K +L+ +E+ LE + KR+ L+ + DL
Sbjct: 1453 LAEWKQKYEESQSELESSQKEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDL 1512
Query: 1415 QADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEA 1474
S + + +L+K ++L AE + + LE + E K R E +Q E
Sbjct: 1513 TEQLGSSGKTIHELEKVRKQLEAEKMELQSALEEAEASLEHEEGKILRAQLEFNQIKAEI 1572
Query: 1475 QREKLQR-EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKD 1533
+R+ ++ E++++ K L SL+ L+ + + +E +L ++ Q S
Sbjct: 1573 ERKLAEKDEEMEQAKRNHLRVVDSLQTSLDAETRSRNEALRVKKKMEGDLNEMEIQLSHA 1632
Query: 1534 EASLAKVKKQLRDLEAKVKDQEEELDEQAGT-------IQMLEQAKLRLEMEMERMRQTH 1586
A+ +KQ++ L++ +KD + +LD+ I ++E+ L+ E+E +R
Sbjct: 1633 NRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAELEELRAVV 1692
Query: 1587 SKEMESR---DEEVEEARQSCQ----------KKLKQMEVQLEEEYEDKQKVLREKRELE 1633
+ SR ++E+ E + Q + K+M+ L + + ++ ++E R E
Sbjct: 1693 EQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQTEVEEAVQECRNAE 1752
Query: 1634 GKL-------ATLSDQVNRRDFESE--KRLRKDLKRTKALLADAQLMLDHLKNSAPS--- 1681
K A +++++ + S +R++K++++T + D Q LD + A
Sbjct: 1753 EKAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---IKDLQHRLDEAEQIALKGGK 1809
Query: 1682 ------KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLS 1735
+ + +L+N+LE + A +VK + E I++L Q ++ K L++ +
Sbjct: 1810 KQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEEDRKNLLRLQDLVD 1869
Query: 1736 RLQREKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLA--QINDLQAQ 1782
+LQ + + + EE +E N + K H+ A+ D+A Q+N L+A+
Sbjct: 1870 KLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQVNKLRAK 1923
Score = 80.1 bits (196), Expect = 2e-14
Identities = 68/319 (21%), Positives = 154/319 (48%), Gaps = 18/319 (5%)
Query: 1247 IEVQLS---------EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSE 1297
+E+QLS ++Q+++ ++ + +L+ A + ++L+ N +E R + L +E
Sbjct: 1625 MEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRANDDLKENIAIVERRNNLLQAE 1684
Query: 1298 LTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAE 1357
L + R E + E + + ++ L +Q +L Q + M+ ++ + + E
Sbjct: 1685 LEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSLINQKKKMDADLSQLQ----TE 1740
Query: 1358 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 1417
+ V + E K ++A+ + + L++E + +E+ K+ +E+ + DLQ
Sbjct: 1741 VEEAVQECRNAEE---KAKKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTIKDLQHR 1796
Query: 1418 SEESQR-ALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQR 1476
+E+++ AL+ KK+ Q+L A +++ + LE +Q RN E K R+ + + + + +
Sbjct: 1797 LDEAEQIALKGGKKQLQKLEARVRELENELEAEQKRNAESVKGMRKSERRIKELTYQTEE 1856
Query: 1477 EKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS 1536
++ +LQ D L + + K+Q EE + K ++ EL + + E+
Sbjct: 1857 DRKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQHELDEAEERADIAESQ 1916
Query: 1537 LAKVKKQLRDLEAKVKDQE 1555
+ K++ + RD+ K ++E
Sbjct: 1917 VNKLRAKSRDIGTKGLNEE 1935
>gi|156104908 myosin heavy chain 6 [Homo sapiens]
Length = 1939
Score = 513 bits (1322), Expect = e-145
Identities = 430/1685 (25%), Positives = 810/1685 (48%), Gaps = 224/1685 (13%)
Query: 366 LKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTL 425
+K++ L+ GKV + ++ G + V ED V + N P D++ED+A L +L+E +VL L
Sbjct: 47 VKAKILSREGGKVIAETEN-GKTVTVKEDQVLQQNPPKFDKIEDMAMLTFLHEPAVLFNL 105
Query: 426 RQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAM 485
++RY A +++TY+G + + P VY+ +V+ ++G +R + PHI++++ AY+ M
Sbjct: 106 KERYAAWMIYTYSGLFCVTVNPYKWLPVYNAEVVAAYRGKKRSEAPPHIFSISDNAYQYM 165
Query: 486 LMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI---------SGNKVFSVEKWQALY 536
L R++QSI++ G SG+GKT + + ++QY A+IA I + NK ++
Sbjct: 166 LTDRENQSILITGESGAGKTVNTKRVIQYFASIAAIGDRGKKDNANANKGTLEDQIIQAN 225
Query: 537 TLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFN 596
LEAFGN+ T+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++
Sbjct: 226 PALEAFGNAKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVIFQLKAERNYH 285
Query: 597 VFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLG 653
+FY +L+ + EL L NN + +++ E + +L A A VLG
Sbjct: 286 IFYQILS----NKKPELLDMLLVTNNPYDYAFVSQGEVSVASIDDSEELMATDSAFDVLG 341
Query: 654 ISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAI 713
+ +E+ + + AI H G ++ E + + A K+AYL+G + +L +
Sbjct: 342 FTSEEKAGVYKLTGAIMHYGNMKFKQKQREEQAEPDGTED-ADKSAYLMGLNSADLLKGL 400
Query: 714 FKHQHKGGT--LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLV 771
+ K G + + S +Q G +A +Y ++F +V+ +
Sbjct: 401 CHPRVKVGNEYVTKGQSVQQVYYSIG----------------ALAKAVYEKMFNWMVTRI 444
Query: 772 NRALKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQE 831
N L++ Q + ++D GF+ + SFE+LC N+T ++LQ+ F+ FV E
Sbjct: 445 NATLETKQPRQYFIGVLDIAGFEIFDFN------SFEQLCINFTNEKLQQFFNHHMFVLE 498
Query: 832 LERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPG 891
E YK+E IE F D D A +D ++ G++ +LEEE + P
Sbjct: 499 QEEYKKEGIEWTFIDFGM---DLQACIDLI------------EKPMGIMSILEEECMFPK 543
Query: 892 ASEDTLLERLF-SYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTK 950
A++ T +L+ ++ G +K ++ + + HF L H GT V+YN+ GWL K
Sbjct: 544 ATDMTFKAKLYDNHLGKSNNFQKPRN--IKGKQEAHFSLIHYAGT--VDYNILGWLEKNK 599
Query: 951 QNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSG-SIAGLEGGSQLALRRATSMRKTF 1009
+P + L Q S K+++ LF A + T SG S G + GS +F
Sbjct: 600 -DPLNETVVALYQKSSLKLMATLFSSYATADTGDSGKSKGGKKKGS------------SF 646
Query: 1010 TTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSS 1069
T ++A+ +++L + L+ ++ + HFV C +P
Sbjct: 647 QT-VSALHRENL--------NKLMTNLRTTHPHFVRCIIP-------------------- 677
Query: 1070 SELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLA 1129
+E P +D PL+ QLR + +L+ +R+ R+G+P+ +++ +FR+R+ +L
Sbjct: 678 NERKAPG---------VMDNPLVMHQLRCNGVLEGIRICRKGFPNRILYGDFRQRYRILN 728
Query: 1130 PHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTS 1189
P + G+ +D R+ E+LL LD++ + G ++VFF+AG L LEE RDE+ S
Sbjct: 729 P-VAIPEGQ---FIDSRKGTEKLLSSLDIDHNQYKFGHTKVFFKAGLLGLLEEMRDERLS 784
Query: 1190 RNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEV 1249
R +T QA RG L R FKK + A+ +Q NI+ GVK+WPW KL+ ++PL++
Sbjct: 785 RIITRMQAQARGQLMRIEFKKIVERRDALLVIQWNIRAFMGVKNWPWMKLYFKIKPLLKS 844
Query: 1250 QLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESAS 1309
+E+++ EE +++ LEK+E R EL L ++L ++ E++ A
Sbjct: 845 AETEKEMATMKEEFGRIKETLEKSEARRKELEEKMVSLLQEKNDLQLQVQAEQDNLNDAE 904
Query: 1310 QLLDAETAERLRAEKEMKELQTQYDALKKQMEV-MEMEVMEARL-IRAAEINGEVDDDDA 1367
+ D +++ E ++KE+ + L+ + E+ E+ + +L +E+ ++DD
Sbjct: 905 ERCDQLIKNKIQLEAKVKEMN---ERLEDEEEMNAELTAKKRKLEDECSELKKDIDD--- 958
Query: 1368 GGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQ------QNKRQL----ERRLGDLQAD 1417
L + +E T+ +++ E+ +++ + K+ L ++ L DLQ +
Sbjct: 959 ---LELTLAKVEKEKHATENKVKNLTEEMAGLDEIIAKLTKEKKALQEAHQQALDDLQVE 1015
Query: 1418 SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQRE 1477
++ + L K +L ++ D + LE ++ +LE+ +R+ + +L E
Sbjct: 1016 EDK----VNSLSKSKVKLEQQVDDLEGSLEQEKKVRMDLERAKRKLEGDLKLTQESIM-- 1069
Query: 1478 KLQREKLQREKDMLLAEAFSLKQQ---LEEKDMDIAGFTQKVVSLEAELQDISSQESKDE 1534
L+ +KLQ E + L + F + QQ +E++ + +K+ +A ++++ + +
Sbjct: 1070 DLENDKLQLE-EKLKKKEFDINQQNSKIEDEQVLALQLQKKLKENQARIEELEEELEAER 1128
Query: 1535 ASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQM------------------LEQAKLRLE 1576
+ AKV+K DL ++++ E L+E G + LE+A L+ E
Sbjct: 1129 TARAKVEKLRSDLSRELEEISERLEEAGGATSVQIEMNKKREAEFQKMRRDLEEATLQHE 1188
Query: 1577 MEMERMRQTHSKEMESRDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELE 1633
+R+ H+ + E++ + +Q +K+ + +++L++ + +++++ K LE
Sbjct: 1189 ATAAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLE 1248
Query: 1634 GKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLML-DHLKNSAPSKREIAQLKNQL 1692
TL DQ N E R++ L +AQ L D A + E +L QL
Sbjct: 1249 KVSRTLEDQAN------EYRVK---------LEEAQRSLNDFTTQRAKLQTENGELARQL 1293
Query: 1693 EESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQ 1752
EE E + + + + ++EDL Q+++ KAK AL L + + + ++ + EE+
Sbjct: 1294 EEKEALISQLTRGKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEET 1353
Query: 1753 E---DMNELMKKHKAAVAQ------------------ASRDLAQ-INDLQAQLEEANKEK 1790
E ++ ++ K + VAQ A + LAQ + D + +E N +
Sbjct: 1354 EAKAELQRVLSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKC 1413
Query: 1791 QELQEKLQALQSQVEFL----EQSMVDKSLVSRQEAK----IRELETRLEFERTQVKRLE 1842
L++ LQ+++E L E+S + + +++ + E + + E +++++ +
Sbjct: 1414 SSLEKTKHRLQNEIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQ 1473
Query: 1843 SLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKH 1902
A L + KL ++ + K +NK LQ ++ D E++GE + E + +
Sbjct: 1474 KEARSLSTELFKLKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRK 1533
Query: 1903 ELEMDLESLEAANQSLQADLK-------LAFKRIGDLQAAIEDEM-ESDENEDLINSEGD 1954
+LE++ L++A + +A L+ A ++A IE ++ E DE +
Sbjct: 1534 QLEVEKLELQSALEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQ 1593
Query: 1955 SDVDS 1959
VDS
Sbjct: 1594 RVVDS 1598
Score = 199 bits (505), Expect = 3e-50
Identities = 183/818 (22%), Positives = 382/818 (46%), Gaps = 40/818 (4%)
Query: 1144 DERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYL 1203
D R +EE+ E LE++ G + V E Q+ + TL A L
Sbjct: 1140 DLSRELEEISE--RLEEAG---GATSVQIEMNKKREAEFQKMRRDLEEATLQHEATAAAL 1194
Query: 1204 ARQHFKKRKIQDLA-----IRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQI-R 1257
++H + +L ++ V++ ++K K + + + +I+ + + E++ R
Sbjct: 1195 RKKHADS--VAELGEQIDNLQRVKQKLEKEKSEFKLELDDVTSNMEQIIKAKANLEKVSR 1252
Query: 1258 NKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETA 1317
+++ + R KLE+A++ N+ +L++ EL +L E L+ T
Sbjct: 1253 TLEDQANEYRVKLEEAQRSLNDFTTQRAKLQTENGELARQL-------EEKEALISQLTR 1305
Query: 1318 ERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYER 1377
+L ++M++L+ Q + K + + AR ++ +A E + +
Sbjct: 1306 GKLSYTQQMEDLKRQLEEEGKAKNALAHALQSARHDCDLLREQYEEETEAKAELQRVLSK 1365
Query: 1378 AVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTA 1437
A EV + + + + + E ++ K++L +RL D + E L+K RL
Sbjct: 1366 ANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEAVEAVNAKCSSLEKTKHRLQN 1425
Query: 1438 ELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS 1497
E++D + +E L+KKQR FD L++ ++ + + + E Q+E L E F
Sbjct: 1426 EIEDLMVDVERSNAAAAALDKKQRNFDKILAEWKQKYEESQSELESSQKEARSLSTELFK 1485
Query: 1498 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1557
LK EE + F ++ +L+ E+ D++ Q + ++ +++K + LE + + +
Sbjct: 1486 LKNAYEESLEHLETFKRENKNLQEEISDLTEQLGEGGKNVHELEKVRKQLEVEKLELQSA 1545
Query: 1558 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE 1617
L+E +++ E LR ++E +++ +++ +DEE+E+A+++ Q+ + ++ L+
Sbjct: 1546 LEEAEASLEHEEGKILRAQLEFNQIKAEIERKLAEKDEEMEQAKRNHQRVVDSLQTSLDA 1605
Query: 1618 EYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKR---LRKDLKRTKALLADAQLM 1671
E + +VLR K+++EG L + Q+ NR E++K+ L+ LK T+ L DA
Sbjct: 1606 ETRSRNEVLRVKKKMEGDLNEMEIQLSHANRMAAEAQKQVKSLQSLLKDTQIQLDDAVRA 1665
Query: 1672 LDHLK-NSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTAL 1730
D LK N A +R L+ +LEE ++RK E E+ + ++ + T+L
Sbjct: 1666 NDDLKENIAIVERRNNLLQAELEELRAVVEQTERSRKLAEQELIETSERVQLLHSQNTSL 1725
Query: 1731 EEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQA---SRDLAQINDLQAQLEEAN 1787
Q +++ + ++Q+ +EE ++ +K K A+ A + +L + D A LE
Sbjct: 1726 INQKKKMESDLTQLQSEVEEAVQECRNAEEKAKKAITDAAMMAEELKKEQDTSAHLE--- 1782
Query: 1788 KEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELETRLEFERTQ----VKRL 1841
+ K+ +++ ++ LQ +++ EQ + K + + EA++RELE LE E+ + VK +
Sbjct: 1783 RMKKNMEQTIKDLQHRLDEAEQIALKGGKKQLQKLEARVRELEGELEAEQKRNAESVKGM 1842
Query: 1842 ESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901
R+KE + E++ + ++ + +++ R +E + ++ + +
Sbjct: 1843 RKSERRIKELTYQTEEDKKNLLRLQDLVDKLQLKVKAYKRQAEEAEEQANTNLSKFRKVQ 1902
Query: 1902 HELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDE 1939
HEL+ E + A + L+ + IG Q ++E
Sbjct: 1903 HELDEAEERADIAESQVN-KLRAKSRDIGAKQKMHDEE 1939
>gi|115527082 myosin, heavy chain 1, skeletal muscle, adult [Homo
sapiens]
Length = 1939
Score = 511 bits (1315), Expect = e-144
Identities = 431/1697 (25%), Positives = 811/1697 (47%), Gaps = 218/1697 (12%)
Query: 376 GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435
GKV K + GA + V +D V N P D++ED+A + +L+E +VL+ L++RY A +++
Sbjct: 58 GKVTAKTEA-GATVTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIY 116
Query: 436 TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495
TY+G + + P VY+ +V+ ++G +R++ PHI++++ AY+ ML R++QSI+
Sbjct: 117 TYSGLFCVTVNPYKWLPVYNAEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176
Query: 496 LLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALYT----------LLEAFGNS 545
+ G SG+GKT + + ++QY ATIA K V + T LLEAFGN+
Sbjct: 177 ITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEVTSGKMQGTLEDQIISANPLLEAFGNA 236
Query: 546 PTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACG 605
T+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++++FY +++
Sbjct: 237 KTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQIMS-- 294
Query: 606 DGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKAC 662
+ +L L N + +++ E + +L A A+++LG + DE+ +
Sbjct: 295 --NKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIEILGFTSDERVSI 352
Query: 663 WFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT 722
+ + A+ H G ++ E + E A KAAYL + +L A+ + K G
Sbjct: 353 YKLTGAVMHYGNMKFKQKQREEQAEPDGT-EVADKAAYLQNLNSADLLKALCYPRVKVG- 410
Query: 723 LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSL 782
+ +G + + G +A +Y ++F +V+ +N+ L + Q
Sbjct: 411 ---NEYVTKGQTVQQVYNAVG----------ALAKAVYDKMFLWMVTRINQQLDTKQPRQ 457
Query: 783 CSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIEL 842
+ ++D GF+ + S E+LC N+T ++LQ+ F+ FV E E YK+E IE
Sbjct: 458 YFIGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
Query: 843 AFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLF 902
F D +D A+ L+ ++ G+ +LEEE + P A++ + +L+
Sbjct: 512 TFIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLY 556
Query: 903 SYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRL 961
+ + + Q P KP HF L H GT V+YN+ GWL+ K +P + L
Sbjct: 557 EQHLGKSNN--FQKPKPAKGKPEAHFSLIHYAGT--VDYNIAGWLDKNK-DPLNETVVGL 611
Query: 962 LQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSL 1021
Q S K ++ LF+G G+ G G +GG + +F T A ++
Sbjct: 612 YQKSAMKTLALLFVGATGAEAEAGG---GKKGGKKKG--------SSFQTVSALFRE--- 657
Query: 1022 CIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCE 1081
++ L+ ++ + HFV C +P +E P
Sbjct: 658 ------NLNKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA---- 687
Query: 1082 AGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYI 1141
++ L+ QLR + +L+ +R+ R+G+P +++++F++R+ VL +
Sbjct: 688 -----MEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ---- 738
Query: 1142 VVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRG 1201
+D ++A E+LL +D++ + G ++VFF+AG L LEE RDE+ ++ +T QA CRG
Sbjct: 739 FIDSKKASEKLLGSIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQLITRTQAMCRG 798
Query: 1202 YLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE 1261
+LAR ++K + +I C+Q N++ VK WPW KL+ ++PL++ +E+++ N E
Sbjct: 799 FLARVEYQKMVERRESIFCIQYNVRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMKE 858
Query: 1262 EIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLR 1321
E ++ + +L K E +R EL L ++L ++ E ++ A + D +++
Sbjct: 859 EFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADSLADAEERCDQLIKTKIQ 918
Query: 1322 AEKEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAVR 1380
E ++KE+ + A ++ E+ + +L +E+ ++DD + K E+
Sbjct: 919 LEAKIKEVTER--AEDEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEKH 973
Query: 1381 EVDFTKKRLQQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQ 1433
+ K L +E ++ + + K+ L ++ L DLQA+ ++ + L K
Sbjct: 974 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK----VNTLTKAKI 1029
Query: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA 1493
+L ++ D + LE ++ +LE+ +R+ + +L A E + +++L +
Sbjct: 1030 KLEQQVDDLEGSLEQEKKIRMDLERAKRKLEGDLKLAQESTMDIENDKQQLDEKLKKKEF 1089
Query: 1494 EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKD 1553
E L+ ++E++ +K+ L+A ++++ + + AS AK +KQ DL ++++
Sbjct: 1090 EMSGLQSKIEDEQALGMQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEE 1149
Query: 1554 QEEELDEQAGT----IQM--------------LEQAKLRLEMEMERMRQTHSKEMESRDE 1595
E L+E G I+M LE+A L+ E +R+ H+ + E
Sbjct: 1150 ISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAELGE 1209
Query: 1596 EV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVN--RRDFES 1650
++ + +Q +K+ +M++++++ + + V + K LE L DQ++ + E
Sbjct: 1210 QIDNLQRVKQKLEKEKSEMKMEIDDLASNMETVSKAKGNLEKMCRALEDQLSEIKTKEEE 1269
Query: 1651 EKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAME 1710
++RL DL +A L + E + QL+E + + + ++A
Sbjct: 1270 QQRLINDLTAQRARL----------------QTESGEYSRQLDEKDTLVSQLSRGKQAFT 1313
Query: 1711 VEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL---MKKHKAAVA 1767
+IE+L Q+++ KAK+AL L + + + ++ + EE+QE EL M K + VA
Sbjct: 1314 QQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQYEEEQEAKAELQRAMSKANSEVA 1373
Query: 1768 Q------------------ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQSQVEFL- 1807
Q A + LAQ + D + +E N + L++ Q LQ++VE L
Sbjct: 1374 QWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTKQRLQNEVEDLM 1433
Query: 1808 ---------------EQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENM 1852
+Q DK L E K + ET E E +Q K SL++ L +
Sbjct: 1434 IDVERTNAACAALDKKQRNFDKILA---EWKQKCEETHAELEASQ-KESRSLSTELFKIK 1489
Query: 1853 EKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLE 1912
E DQ K +NK LQ+++ D E++ E ++ E + K ++E + L+
Sbjct: 1490 NAYEESLDQL----ETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQ 1545
Query: 1913 AANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVKSWL 1972
AA + +A L+ +I +Q + ++++S+ + + +E D ++D + + V+S
Sbjct: 1546 AALEEAEASLEHEEGKILRIQLEL-NQVKSEVDRKI--AEKDEEIDQMKRNHIRIVESMQ 1602
Query: 1973 SKNKGPSKAASDDGSLK 1989
S ++ +D LK
Sbjct: 1603 STLDAEIRSRNDAIRLK 1619
Score = 194 bits (494), Expect = 6e-49
Identities = 156/687 (22%), Positives = 334/687 (48%), Gaps = 47/687 (6%)
Query: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
E+ R ++++ ++++K E+ ++ N+L RL++ E + +L DE++T SQL
Sbjct: 1250 EKMCRALEDQLSEIKTKEEEQQRLINDLTAQRARLQTESGEYSRQL-DEKDT--LVSQLS 1306
Query: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
+ A + E+ ++L+ + A ++ + L+R ++ +A E +
Sbjct: 1307 RGKQAFTQQIEELKRQLEEEIKAKSALAHALQSSRHDCDLLREQY----EEEQEAKAELQ 1362
Query: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
+A EV + + + + + E ++ K++L +RL D + E L+K
Sbjct: 1363 RAMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNAKCASLEKTK 1422
Query: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLL 1492
QRL E++D + +E L+KKQR FD L++ ++ + + E Q+E L
Sbjct: 1423 QRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKESRSLS 1482
Query: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVK 1552
E F +K EE + ++ +L+ E+ D++ Q ++ + +++K + +E +
Sbjct: 1483 TELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKS 1542
Query: 1553 DQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQME 1612
+ + L+E +++ E LR+++E+ +++ +++ +DEE+++ +++ + ++ M+
Sbjct: 1543 ELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQ 1602
Query: 1613 VQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLML 1672
L+ E + +R K+++EG L + Q+N + + + LR + + T+A+L D QL L
Sbjct: 1603 STLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR-NYRNTQAILKDTQLHL 1661
Query: 1673 DH-LKNSAPSKREIAQ-------LKNQLEESEFTCAAAVKARKAMEVEIED-------LH 1717
D L++ K ++A L+ ++EE T ++RK E E+ D LH
Sbjct: 1662 DDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLH 1721
Query: 1718 LQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED----------MNELMKKHK---A 1764
Q + K LE +S++Q E +I +E M E +KK + A
Sbjct: 1722 TQNTSLINTKKKLETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1781
Query: 1765 AVAQASRDLAQ-INDLQAQLEEA--------NKEKQELQEKLQALQSQVEFLEQSMVDK- 1814
+ + ++L Q + DLQ +L+EA K+ Q+L+ +++ L+ +VE ++ V+
Sbjct: 1782 HLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAV 1841
Query: 1815 SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNK 1874
+ + E K++EL + E +R + RL+ L +L+ ++ + ++ N + +
Sbjct: 1842 KGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFR 1901
Query: 1875 RLQRQLRDTKEEMGELARKEAEASRKK 1901
R+Q +L + EE ++A + R K
Sbjct: 1902 RIQHELEEA-EERADIAESQVNKLRVK 1927
Score = 105 bits (262), Expect = 5e-22
Identities = 137/611 (22%), Positives = 266/611 (43%), Gaps = 104/611 (17%)
Query: 1256 IRNKDEEIQQLRSKLEKA-EKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDA 1314
+R + EE Q+ +++L++A K +E+ + E+ + T EL + + + A +L DA
Sbjct: 1347 LREQYEEEQEAKAELQRAMSKANSEVAQWRTKYETDAIQRTEELEEAKK--KLAQRLQDA 1404
Query: 1315 ETAERLRA-EKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL 1373
E E + A + L+ L+ ++E + ++V AA + + D EW+
Sbjct: 1405 E--EHVEAVNAKCASLEKTKQRLQNEVEDLMIDVERTNAACAALDKKQRNFDKILAEWKQ 1462
Query: 1374 KYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQ 1433
K E E +LE Q+ R L L ++ EES L+ LK++ +
Sbjct: 1463 KCE---------------ETHAELEASQKESRSLSTELFKIKNAYEESLDQLETLKRENK 1507
Query: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFD---SELSQAHEEAQ-----------REKL 1479
L E+ D + R HELEK +++ + SEL A EEA+ R +L
Sbjct: 1508 NLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKSELQAALEEAEASLEHEEGKILRIQL 1567
Query: 1480 QREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVS---------------LEAELQ 1524
+ +++ E D +AE Q++ + I Q + +E +L
Sbjct: 1568 ELNQVKSEVDRKIAEKDEEIDQMKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLN 1627
Query: 1525 DISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGT-------IQMLEQAKLRLEM 1577
++ Q + A+ + R+ +A +KD + LD+ + + M+E+ L+
Sbjct: 1628 EMEIQLNHANRMAAEALRNYRNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQA 1687
Query: 1578 EMERMRQTHSKEMESR---DEEVEEARQSCQ-------------KKLKQMEVQLEEEYED 1621
E+E +R T + SR ++E+ +A + Q KKL+ Q++ E ED
Sbjct: 1688 EIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQIQGEMED 1747
Query: 1622 KQKVLREKRELEGKL-------ATLSDQVNRRDFESE--KRLRKDLKRTKALLADAQLML 1672
+++E R E K A +++++ + S +R++K+L++T + D Q L
Sbjct: 1748 ---IIQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT---VKDLQHRL 1801
Query: 1673 DHLKNSAPS---------KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI 1723
D + A + + +L+ ++E + AVK + E ++++L Q ++
Sbjct: 1802 DEAEQLALKGGKKQIQKLEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEED 1861
Query: 1724 AKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLA--QI 1776
K L++ + +LQ + + + EE +E N + K H+ A+ D+A Q+
Sbjct: 1862 RKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQV 1921
Query: 1777 NDLQAQLEEAN 1787
N L+ + E +
Sbjct: 1922 NKLRVKSREVH 1932
Score = 82.0 bits (201), Expect = 5e-15
Identities = 68/301 (22%), Positives = 147/301 (48%), Gaps = 11/301 (3%)
Query: 1257 RNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAET 1316
RN ++ + L+ A + + +L+ +E R + L +E+ + R T E +
Sbjct: 1648 RNTQAILKDTQLHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1707
Query: 1317 AERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD-DAGGEWRLKY 1375
E L A + ++ L TQ +L + +E ++ ++I GE++D K
Sbjct: 1708 QELLDASERVQLLHTQNTSLINTKKKLETDI--------SQIQGEMEDIIQEARNAEEKA 1759
Query: 1376 ERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKKKCQR 1434
++A+ + + L++E + +E+ K+ LE+ + DLQ +E+++ AL+ KK+ Q+
Sbjct: 1760 KKAITDAAMMAEELKKEQDTSAHLERM-KKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK 1818
Query: 1435 LTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAE 1494
L A +++ + +E +Q RN E K R+ + ++ + + + ++ +LQ D L A+
Sbjct: 1819 LEARVRELEGEVESEQKRNVEAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAK 1878
Query: 1495 AFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQ 1554
S K+Q EE + K ++ EL++ + E+ + K++ + R++ K+ +
Sbjct: 1879 VKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSREVHTKIISE 1938
Query: 1555 E 1555
E
Sbjct: 1939 E 1939
Score = 56.6 bits (135), Expect = 2e-07
Identities = 68/267 (25%), Positives = 125/267 (46%), Gaps = 44/267 (16%)
Query: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERN----ELRLNSDR----------------- 1286
++ + E + EI++LR+ LE+ E+ R EL S+R
Sbjct: 1674 QLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1733
Query: 1287 LESRISELTSELTD----ERNTGESASQLLD--AETAERLRAEKEMKELQTQYDALKKQM 1340
LE+ IS++ E+ D RN E A + + A AE L+ E ++ + +KK +
Sbjct: 1734 LETDISQIQGEMEDIIQEARNAEEKAKKAITDAAMMAEELKKE---QDTSAHLERMKKNL 1790
Query: 1341 EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL-KYERAVREVDFTKKRLQQEFEDKLEV 1399
E ++ ++ RL A ++ + GG+ ++ K E VRE++ + E E K V
Sbjct: 1791 E-QTVKDLQHRLDEAEQLALK------GGKKQIQKLEARVRELEG-----EVESEQKRNV 1838
Query: 1400 EQ-QNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1458
E + R+ ER++ +L +EE ++ + +L+ +L A+++ K E + +++
Sbjct: 1839 EAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNVNLS 1898
Query: 1459 KQRRFDSELSQAHEEAQREKLQREKLQ 1485
K RR EL +A E A + Q KL+
Sbjct: 1899 KFRRIQHELEEAEERADIAESQVNKLR 1925
Score = 35.0 bits (79), Expect = 0.75
Identities = 36/172 (20%), Positives = 79/172 (45%), Gaps = 16/172 (9%)
Query: 1181 EEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLF 1240
E ++++ TS +L + + + + + LA++ +K I+K L
Sbjct: 1772 ELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK-----------LE 1820
Query: 1241 TTVRPLIEVQLSEEQIRNKDEEIQQLRS---KLEKAEKERNELRLNSDRLESRISELTSE 1297
VR L E ++ EQ RN E ++ LR K+++ + E R N RL+ + +L ++
Sbjct: 1821 ARVREL-EGEVESEQKRNV-EAVKGLRKHERKVKELTYQTEEDRKNILRLQDLVDKLQAK 1878
Query: 1298 LTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVME 1349
+ + E A + + ++ R + E++E + + D + Q+ + ++ E
Sbjct: 1879 VKSYKRQAEEAEEQSNVNLSKFRRIQHELEEAEERADIAESQVNKLRVKSRE 1930
>gi|110624781 myosin, heavy polypeptide 13, skeletal muscle [Homo
sapiens]
Length = 1938
Score = 507 bits (1306), Expect = e-143
Identities = 411/1671 (24%), Positives = 810/1671 (48%), Gaps = 205/1671 (12%)
Query: 385 DGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLV 444
D +L ++ D V N P D++ED+A + +L+E +VL+ L++RY A +++TY+G +
Sbjct: 66 DDRMLTLNNDQVFPMNPPKFDKIEDMAMMTHLHEPAVLYNLKERYAAWMIYTYSGLFCVT 125
Query: 445 LGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGK 504
+ P VY +V+ ++G +R++ PHI++++ AY+ ML R +QSI++ G SG+GK
Sbjct: 126 VNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRDNQSILITGESGAGK 185
Query: 505 TTSCQHLVQYLATIAGISGNKVFSVEKWQALYT----------LLEAFGNSPTIINGNAT 554
T + + ++QY ATIA ++G+K + + T LLEAFGN+ T+ N N++
Sbjct: 186 TVNTKRVIQYFATIA-VTGDKKKETQPGKMQGTLEDQIIQANPLLEAFGNAKTVRNDNSS 244
Query: 555 RFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELH 614
RF + + + F G++ASA I+T LLEK RV + +SE ++++FY +++ + EL
Sbjct: 245 RFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLSSERSYHIFYQIMS----NKKPELI 300
Query: 615 LNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKACWFILAAIYH 671
L N F +++ E + +L A A+ +LG S +E+ + + A+ H
Sbjct: 301 DLLLISTNPFDFPFVSQGEVTVASIDDSEELLATDNAIDILGFSSEEKVGIYKLTGAVMH 360
Query: 672 LGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTLQRSTSFRQ 731
G ++ E + E A KA YL+G + E+ + + K G + +
Sbjct: 361 YGNMKFKQKQREEQAEPDGT-EVADKAGYLMGLNSAEMLKGLCCPRVKVG----NEYVTK 415
Query: 732 GPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMMIVDTP 791
G + + G +A +Y ++F +V+ +N+ L + Q + ++D
Sbjct: 416 GQNVQQVTNSVG----------ALAKAVYEKMFLWMVTRINQQLDTKQPRQYFIGVLDIA 465
Query: 792 GFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPT 851
GF+ + S E+LC N+T ++LQ+ F+ FV E E YK+E IE F D
Sbjct: 466 GFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWEFIDF---- 515
Query: 852 DDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGD 911
+D A+ L+ ++ G+ +LEEE + P A++ + +L+ + + +
Sbjct: 516 -----GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLYDQHLGKSNN 564
Query: 912 KKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIIS 971
+ P ++ HF L H GT V+YN+ GWL+ K +P + L Q S K++S
Sbjct: 565 FQKPKPAKGKAEA-HFSLVHYAGT--VDYNIAGWLDKNK-DPLNETVVGLYQKSSLKLLS 620
Query: 972 NLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDA 1031
LF AG+ T G GGS+ ++ S +T ++AV +++L +
Sbjct: 621 FLFSNYAGAET-------GDSGGSKKGGKKKGSSFQT----VSAVFRENL--------NK 661
Query: 1032 LIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPL 1091
L+ ++ + HFV C +P +E P +D L
Sbjct: 662 LMTNLRSTHPHFVRCLIP--------------------NETKTPG---------VMDHYL 692
Query: 1092 LRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEE 1151
+ QLR + +L+ +R+ R+G+P +++++F++R+ +L + +D + A E+
Sbjct: 693 VMHQLRCNGVLEGIRICRKGFPSRILYADFKQRYRILNASAIPEGQ----FIDSKNASEK 748
Query: 1152 LLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKR 1211
LL +D+++ G ++VFF+AG L LEE RDE+ +T QA CRGYL R FKK
Sbjct: 749 LLNSIDVDREQFRFGNTKVFFKAGLLGLLEEMRDEKLVTLMTSTQAVCRGYLMRVEFKKM 808
Query: 1212 KIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLE 1271
+ +I C+Q NI+ VK WPW LF ++PL++ +E+++ E+ ++ + +L
Sbjct: 809 MERRDSIFCIQYNIRSFMNVKHWPWMNLFFKIKPLLKSAEAEKEMATMKEDFERTKEELA 868
Query: 1272 KAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQT 1331
++E R EL L ++L ++ E A + + ++ E ++KEL
Sbjct: 869 RSEARRKELEEKMVSLLQEKNDLQLQVQSETENLMDAEERCEGLIKSKILLEAKVKELT- 927
Query: 1332 QYDALKKQMEVMEMEVMEARLI--RAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRL 1389
+ L+++ E+ V + R + + + + ++DD + K E+ + K L
Sbjct: 928 --ERLEEEEEMNSELVAKKRNLEDKCSSLKRDIDDLEL---TLTKVEKEKHATENKVKNL 982
Query: 1390 QQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQRLTAELQDT 1442
+E E+ + + K+ L ++ L DLQ + E+ L ++ K ++ T +L+ +
Sbjct: 983 SEEMTALEENISKLTKEKKSLQEAHQQTLDDLQVE-EDKVNGLIKINAKLEQQTDDLEGS 1041
Query: 1443 KLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREKLQREKLQREKDMLLAEAFSLK 1499
LE ++ +LE+ +R+ + +L + E + + +K Q E+ ++K+ L++ L+
Sbjct: 1042 ---LEQEKKLRADLERAKRKLEGDLKMSQESIMDLENDKQQIEEKLKKKEFELSQ---LQ 1095
Query: 1500 QQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELD 1559
+++++ + F +K+ L+A ++++ + + AK++KQ DL ++++ E L+
Sbjct: 1096 AKIDDEQVHSLQFQKKIKELQARIEELEEEIEAEHTLRAKIEKQRSDLARELEEISERLE 1155
Query: 1560 EQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEY 1619
E +G + + E E ++MR +++E + E + +KK +L E+
Sbjct: 1156 EASGATSAQIEMNKKREAEFQKMR----RDLEEATLQHEATAATLRKKQADSVAELGEQI 1211
Query: 1620 ED----KQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLAD-------- 1667
++ KQK+ +EK EL+ ++ ++ + E+ + + +++RT + D
Sbjct: 1212 DNLQRVKQKLEKEKSELKMEIDDMASNI-----EALSKSKSNIERTCRTVEDQFSEIKAK 1266
Query: 1668 ----AQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDI 1723
QL+ D A + + +L +++EE E + K+++A+ ++E+L Q+++
Sbjct: 1267 DEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALTQQLEELKRQMEEE 1326
Query: 1724 AKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL---MKKHKAAVAQ------------ 1768
KAK A+ L + + + ++ + EE+QE EL + K + VAQ
Sbjct: 1327 TKAKNAMAHALQSSRHDCDLLREQYEEEQEAKAELQRALSKANSEVAQWRTKYETDAIQR 1386
Query: 1769 ------ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQSQVE----FLEQSMVDKSLV 1817
A + LAQ + + + E AN + L++ Q LQ +VE LE+S + +
Sbjct: 1387 TEELEEAKKKLAQRLQEAEENTETANSKCASLEKTKQRLQGEVEDLMRDLERSHTACATL 1446
Query: 1818 SRQEAK----IRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQN 1873
+++ + E + +L+ + +++ + + L + K+ ++ + + +N
Sbjct: 1447 DKKQRNFDKVLAEWKQKLDESQAELEAAQKESRSLSTELFKMRNAYEEVVDQLETLRREN 1506
Query: 1874 KRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQ 1933
K LQ ++ D E++ E + EA + K +E + L+ A + ++ L+ +I +Q
Sbjct: 1507 KNLQEEISDLTEQIAETGKNLQEAEKTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQ 1566
Query: 1934 ---AAIEDEM-----ESDENEDLINSEG-------DSDVDSELEDRVDGVK 1969
+ ++ E+ E DE + + S +D+E+ R D ++
Sbjct: 1567 LELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVLDAEIRSRNDALR 1617
Score = 190 bits (483), Expect = 1e-47
Identities = 171/701 (24%), Positives = 332/701 (47%), Gaps = 64/701 (9%)
Query: 1247 IEVQLSEEQIRNKDEE----IQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDER 1302
+E Q SE I+ KDE+ I L + + + + EL + ES IS+LT
Sbjct: 1256 VEDQFSE--IKAKDEQQTQLIHDLNMQKARLQTQNGELSHRVEEKESLISQLTKSKQALT 1313
Query: 1303 NTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AEINGE 1361
E + ++ ET + ++ + D L++Q E E + +A L RA ++ N E
Sbjct: 1314 QQLEELKRQMEEETKAKNAMAHALQSSRHDCDLLREQYE--EEQEAKAELQRALSKANSE 1371
Query: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421
V +WR KYE + + E ++ K++L +RL + + ++E +
Sbjct: 1372 V------AQWRTKYETDAIQ--------------RTEELEEAKKKLAQRLQEAEENTETA 1411
Query: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481
L+K QRL E++D LE L+KKQR FD L++ ++ + +
Sbjct: 1412 NSKCASLEKTKQRLQGEVEDLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQAEL 1471
Query: 1482 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVK 1541
E Q+E L E F ++ EE + ++ +L+ E+ D++ Q ++ +L + +
Sbjct: 1472 EAAQKESRSLSTELFKMRNAYEEVVDQLETLRRENKNLQEEISDLTEQIAETGKNLQEAE 1531
Query: 1542 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1601
K + +E + D + L+E G+++ E LR+++E+ +++ +++ +DEE+E+ +
Sbjct: 1532 KTKKLVEQEKSDLQVALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLK 1591
Query: 1602 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESEKRLRKDL 1658
++ Q+ + ++ L+ E + LR K+++EG L + Q+ NR+ E++K LR
Sbjct: 1592 RNSQRAAEALQSVLDAEIRSRNDALRLKKKMEGDLNEMEIQLGHSNRQMAETQKHLR--- 1648
Query: 1659 KRTKALLADAQLMLDH-LKNSAPSKREIA-------QLKNQLEESEFTCAAAVKARKAME 1710
+ L D+QL LD L+++ K ++A L +LEE + + R+ E
Sbjct: 1649 -TVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSE 1707
Query: 1711 VEIED-------LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHK 1763
E+ D LH Q + K LE +++ Q E++N ++E + + E KK
Sbjct: 1708 QELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQA---EVENSIQESR-NAEEKAKKAI 1763
Query: 1764 AAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQE 1821
A + +L + D A LE + K+ L++ ++ LQ +++ EQ + K + + E
Sbjct: 1764 TDAAMMAEELKKEQDTSAHLE---RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLE 1820
Query: 1822 AKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLR 1881
++RELE L+ E+ + A + + ++++T + ++ R ++ +LQ +++
Sbjct: 1821 NRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVK 1880
Query: 1882 DTK---EEMGELARKEAEASRK-KHELEMDLESLEAANQSL 1918
K EE E A + R+ +HELE E + A +
Sbjct: 1881 SYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQV 1921
Score = 70.1 bits (170), Expect = 2e-11
Identities = 60/304 (19%), Positives = 145/304 (47%), Gaps = 9/304 (2%)
Query: 1252 SEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQL 1311
+++ +R +++ + L+ A + +L+ +E R L EL + + E +
Sbjct: 1643 TQKHLRTVQGQLKDSQLHLDDALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERT 1702
Query: 1312 LDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEW 1371
E L A ++ L +Q +L + +E ++ + + AE+ + + E
Sbjct: 1703 RRLSEQELLDASDRVQLLHSQNTSLINTKKKLEADIAQCQ----AEVENSIQESRNAEE- 1757
Query: 1372 RLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKK 1430
K ++A+ + + L++E + +E+ K+ LE+ + DLQ +E+++ AL+ KK
Sbjct: 1758 --KAKKAITDAAMMAEELKKEQDTSAHLERM-KKNLEQTVKDLQHRLDEAEQLALKGGKK 1814
Query: 1431 KCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDM 1490
+ Q+L +++ + L+ +Q R E K +++ ++ + +A+ + +LQ D
Sbjct: 1815 QIQKLENRVRELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDK 1874
Query: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550
L A+ S K+Q EE + + ++ EL++ + + E+ + K++ + RD+ ++
Sbjct: 1875 LQAKVKSYKRQAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQ 1934
Query: 1551 VKDQ 1554
++
Sbjct: 1935 KMEE 1938
Score = 56.6 bits (135), Expect = 2e-07
Identities = 109/534 (20%), Positives = 222/534 (41%), Gaps = 63/534 (11%)
Query: 1103 DAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSS 1162
D MR + + + +R FD + +K + E A ++ L E
Sbjct: 1431 DLMRDLERSHTACATLDKKQRNFDKVLAEWKQKLDESQA---ELEAAQKESRSLSTELFK 1487
Query: 1163 CCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQ 1222
V + TL R + E+ S +LT Q A G ++ K +K+ + +Q
Sbjct: 1488 MRNAYEEVVDQLETLRRENKNLQEEIS-DLTE-QIAETGKNLQEAEKTKKLVEQEKSDLQ 1545
Query: 1223 KNIKKNKGVKDWPWWKLFTTVRPLIEVQLS-EEQIRNKDEEIQQLRSKLEKAEKERN--- 1278
+++ +G + K+ L +V+ + ++ KDEEI+QL+ ++A +
Sbjct: 1546 VALEEVEGSLEHEESKILRVQLELSQVKSELDRKVIEKDEEIEQLKRNSQRAAEALQSVL 1605
Query: 1279 --ELRLNSDRLESRISELTSELTD-ERNTGESASQLLDAETAERLRA-EKEMKELQTQYD 1334
E+R +D L + ++ +L + E G S Q+ AET + LR + ++K+ Q D
Sbjct: 1606 DAEIRSRNDALRLK-KKMEGDLNEMEIQLGHSNRQM--AETQKHLRTVQGQLKDSQLHLD 1662
Query: 1335 A-------LKKQMEVME---------MEVMEARLIRAAEINGEVDDD--DAGGEWRLKYE 1376
LK+Q+ ++E +E M+ L + + + DA +L +
Sbjct: 1663 DALRSNEDLKEQLAIVERRNGLLLEELEEMKVALEQTERTRRLSEQELLDASDRVQLLHS 1722
Query: 1377 RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT 1436
+ ++ TKK+L+ + Q + ++E + + + E++++A+ + L
Sbjct: 1723 QNTSLIN-TKKKLEADIA-------QCQAEVENSIQESRNAEEKAKKAITDAAMMAEELK 1774
Query: 1437 AELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAF 1496
E QDT HLE ++K + +L +EA++ L+ K Q +K L
Sbjct: 1775 KE-QDTSAHLE-------RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQK--LENRVR 1824
Query: 1497 SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASL-----------AKVKKQLR 1545
L+ +L+ + A + E ++++++ Q +D ++ AKVK R
Sbjct: 1825 ELENELDVEQKRGAEALKGAHKYERKVKEMTYQAEEDHKNILRLQDLVDKLQAKVKSYKR 1884
Query: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE 1599
E + +L LE+A R ++ ++ + +K + +++EE
Sbjct: 1885 QAEEAEEQANTQLSRCRRVQHELEEAAERADIAESQVNKLRAKSRDVGSQKMEE 1938
>gi|153791586 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 506 bits (1304), Expect = e-143
Identities = 428/1678 (25%), Positives = 814/1678 (48%), Gaps = 226/1678 (13%)
Query: 376 GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435
GKV VK + GA L V +D V N P D++ED+A + +L+E +VL+ L++RY A +++
Sbjct: 58 GKVTVKTE-GGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIY 116
Query: 436 TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495
TY+G + + P VY +V+ ++G +R++ PHI++++ AY+ ML R++QSI+
Sbjct: 117 TYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176
Query: 496 LLGSSGSGKTTSCQHLVQYLATIA--------GISGNKVFSVEKWQALYT--LLEAFGNS 545
+ G SG+GKT + + ++QY ATIA I+ K+ + Q + LLEAFGN+
Sbjct: 177 ITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNA 236
Query: 546 PTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACG 605
T+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++++FY + +
Sbjct: 237 KTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITS-- 294
Query: 606 DGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKAC 662
+ EL L N + +++ E + +L A A+ +LG + +E+ +
Sbjct: 295 --NKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSI 352
Query: 663 WFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT 722
+ + A+ H G ++ E + E A KAAYL + +L A+ + K G
Sbjct: 353 YKLTGAVMHYGNLKFKQKQREEQAEPDGT-EVADKAAYLQSLNSADLLKALCYPRVKVG- 410
Query: 723 LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSL 782
+ +G + + G +A +Y ++F +V+ +N+ L + Q
Sbjct: 411 ---NEYVTKGQTVEQVSNAVG----------ALAKAVYEKMFLWMVARINQQLDTKQPRQ 457
Query: 783 CSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIEL 842
+ ++D GF+ + S E+LC N+T ++LQ+ F+ FV E E YK+E IE
Sbjct: 458 YFIGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
Query: 843 AFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLF 902
F D +D A+ L+ ++ G+ +LEEE + P A++ + +L+
Sbjct: 512 TFIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLY 556
Query: 903 SYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRL 961
+ + + Q P + K HF L H G V+YN+TGWL K +P + L
Sbjct: 557 DQHLGKSAN--FQKPKVVKGKAEAHFALIHYAGV--VDYNITGWLEKNK-DPLNETVVGL 611
Query: 962 LQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSL 1021
Q S K ++ LF G A G AG GG++ ++ S +T ++A+ +++L
Sbjct: 612 YQKSAMKTLAQLFSG----AQTAEGEGAG--GGAKKGGKKKGSSFQT----VSALFRENL 661
Query: 1022 CIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCE 1081
+ L+ ++ + HFV C +P +E P
Sbjct: 662 --------NKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA---- 689
Query: 1082 AGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYI 1141
++ L+ QLR + +L+ +R+ R+G+P +++++F++R+ VL +
Sbjct: 690 -----MEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ---- 740
Query: 1142 VVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRG 1201
+D ++A E+LL +D++ + G ++VFF+AG L LEE RD++ ++ +T QA CRG
Sbjct: 741 FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRG 800
Query: 1202 YLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE 1261
+LAR +++ + AI C+Q NI+ VK WPW KLF ++PL++ +E+++ E
Sbjct: 801 FLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 860
Query: 1262 EIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLR 1321
E Q+++ +L K+E +R EL L ++L ++ E A + D +++
Sbjct: 861 EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQ 920
Query: 1322 AEKEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAVR 1380
E ++KE+ + A ++ E+ + +L +E+ ++DD + K E+
Sbjct: 921 LEAKIKEVTER--AEDEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEKH 975
Query: 1381 EVDFTKKRLQQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQ 1433
+ K L +E ++ + + K+ L ++ L DLQA+ ++ + L K
Sbjct: 976 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK----VNTLTKAKI 1031
Query: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREKLQREKLQREKDM 1490
+L ++ D + LE ++ +LE+ +R+ + +L A E + + EK Q ++ ++K+
Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF 1091
Query: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550
E +L+ ++E++ +K+ L+A ++++ + + AS AK +KQ DL +
Sbjct: 1092 ---EISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRE 1148
Query: 1551 VKDQEEELDEQAGT----IQM--------------LEQAKLRLEMEMERMRQTHSKEMES 1592
+++ E L+E G I+M LE+A L+ E +R+ H+ +
Sbjct: 1149 LEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAE 1208
Query: 1593 RDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVN--RRD 1647
E++ + +Q +K+ +M++++++ + + V + K LE TL DQ++ +
Sbjct: 1209 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSK 1268
Query: 1648 FESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARK 1707
E ++RL DL + L + E + QL+E E + + ++
Sbjct: 1269 EEEQQRLINDLTAQRGRL----------------QTESGEFSRQLDEKEALVSQLSRGKQ 1312
Query: 1708 AMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVA 1767
A +IE+L Q+++ KAK AL L + + + ++ + EE+QE EL + A++
Sbjct: 1313 AFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQR----ALS 1368
Query: 1768 QASRDLAQ-----INDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEA 1822
+A+ ++AQ D + EE + K++L ++LQA + VE V+ S ++
Sbjct: 1369 KANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVE-----AVNAKCASLEKT 1423
Query: 1823 KIRELETRLEFERTQVKRLESLASRL---KENMEKLTEERDQRIAAENREKEQNKR---- 1875
K R L+ +E V+R + + L + N +K+ E Q+ + E E +++
Sbjct: 1424 KQR-LQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARS 1482
Query: 1876 ---------------------LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAA 1914
L+R+ ++ ++E+ +L + AE ++ HELE + +E
Sbjct: 1483 LGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE 1542
Query: 1915 NQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD---SELEDRVDGVK 1969
LQA L+ + +A++E E L ++ S+VD +E ++ +D +K
Sbjct: 1543 KCELQAALE-------EAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLK 1593
Score = 186 bits (471), Expect = 3e-46
Identities = 158/694 (22%), Positives = 330/694 (47%), Gaps = 61/694 (8%)
Query: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
E+ R ++++ +L+SK E+ ++ N+L RL++ E + +L DE+ SQL
Sbjct: 1252 EKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQL-DEKEA--LVSQLS 1308
Query: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
+ A + E+ ++L+ + A ++ + L+R ++ ++ E +
Sbjct: 1309 RGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQY----EEEQESKAELQ 1364
Query: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
+A EV + + + + + E ++ K++L +RL + E L+K
Sbjct: 1365 RALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTK 1424
Query: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLL 1492
QRL E++D L +E L+KKQR FD L++ ++ + + E Q+E L
Sbjct: 1425 QRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLG 1484
Query: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ---ESKDEASLAKVKKQLR---- 1545
E F +K EE + ++ +L+ E+ D++ Q K L K+KKQ+
Sbjct: 1485 TELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKC 1544
Query: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQ 1605
+L+A +++ E L+ + G I LR+++E+ +++ +++ +DEE+++ +++
Sbjct: 1545 ELQAALEEAEASLEHEEGKI-------LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHI 1597
Query: 1606 KKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL 1665
+ ++ M+ L+ E + +R K+++EG L + Q+N + + + LR + + T+ +L
Sbjct: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR-NYRNTQGIL 1656
Query: 1666 ADAQLMLDH-LKNSAPSKREIAQ-------LKNQLEESEFTCAAAVKARKAMEVEIED-- 1715
D Q+ LD L++ K ++A L+ ++EE T ++RK E E+ D
Sbjct: 1657 KDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDAS 1716
Query: 1716 -----LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED----------MNELMK 1760
LH Q + K LE +S++Q E +I +E M E +K
Sbjct: 1717 ERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELK 1776
Query: 1761 KHK---AAVAQASRDLAQ-INDLQAQLEEA--------NKEKQELQEKLQALQSQVEFLE 1808
K + A + + +++ Q + DLQ +L+EA K+ Q+L+ +++ L+ +VE +
Sbjct: 1777 KEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836
Query: 1809 QSMVDK-SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAEN 1867
+ + + + E +++EL + E +R + RL+ L +L+ ++ + ++ N
Sbjct: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896
Query: 1868 REKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901
+ ++LQ +L + EE ++A + R K
Sbjct: 1897 TNLAKFRKLQHELEEA-EERADIAESQVNKLRVK 1929
Score = 103 bits (257), Expect = 2e-21
Identities = 124/598 (20%), Positives = 260/598 (43%), Gaps = 78/598 (13%)
Query: 1256 IRNKDEEIQQLRSKLEKA-EKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDA 1314
+R + EE Q+ +++L++A K E+ + E+ + T EL + + + +Q L A
Sbjct: 1349 LREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAK---KKLAQRLQA 1405
Query: 1315 ETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLK 1374
+ L+ L+ ++E + ++V AA + + D EW+ K
Sbjct: 1406 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1465
Query: 1375 YERAVREVDFTKKRLQ-------------QEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421
E E++ ++K + +E D+LE ++ + L++ + DL E
Sbjct: 1466 CEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525
Query: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481
+ + +L+K +++ E + + LE + E K R EL+Q E R+ ++
Sbjct: 1526 GKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK 1585
Query: 1482 EKLQREKDMLLAEAFSLKQQLEEK-DMDIAGFTQKV---VSLEAELQDISSQESKDEASL 1537
++ E D L + + ++ D +I + +E +L ++ Q +
Sbjct: 1586 DE---EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1642
Query: 1538 AKVKKQLRDLEAKVKDQEEELDEQAGT-------IQMLEQAKLRLEMEMERMRQTHSKEM 1590
A+ + R+ + +KD + LD+ + + M+E+ L+ E+E +R T +
Sbjct: 1643 AEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1702
Query: 1591 ESR---DEEVEEARQSCQ-------------KKLKQMEVQLEEEYEDKQKVLREKRELEG 1634
SR ++E+ +A + Q KKL+ Q++ E ED +L+E R E
Sbjct: 1703 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMED---ILQEARNAEE 1759
Query: 1635 KL-------ATLSDQVNRRDFESE--KRLRKDLKRTKALLADAQLMLDHLKNSAPS---- 1681
K A +++++ + S +R++K++++T + D QL LD + A
Sbjct: 1760 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---VKDLQLRLDEAEQLALKGGKK 1816
Query: 1682 -----KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSR 1736
+ + +L+ ++E + A AVK + E +++L Q ++ K L++ + +
Sbjct: 1817 QIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDK 1876
Query: 1737 LQREKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLA--QINDLQAQLEEAN 1787
LQ + + + EE +E N + K H+ A+ D+A Q+N L+ + E +
Sbjct: 1877 LQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVH 1934
Score = 81.6 bits (200), Expect = 7e-15
Identities = 68/301 (22%), Positives = 146/301 (48%), Gaps = 11/301 (3%)
Query: 1257 RNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAET 1316
RN ++ + L+ A + + +L+ +E R + L +E+ + R T E +
Sbjct: 1650 RNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1709
Query: 1317 AERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD-DAGGEWRLKY 1375
E L A + ++ L TQ +L + +E ++ +++ GE++D K
Sbjct: 1710 QELLDASERVQLLHTQNTSLINTKKKLETDI--------SQMQGEMEDILQEARNAEEKA 1761
Query: 1376 ERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKKKCQR 1434
++A+ + + L++E + +E+ K+ +E+ + DLQ +E+++ AL+ KK+ Q+
Sbjct: 1762 KKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1820
Query: 1435 LTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAE 1494
L A +++ + +E +Q RN E K R+ + + + + + ++ +LQ D L A+
Sbjct: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1880
Query: 1495 AFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQ 1554
S K+Q EE + K L+ EL++ + E+ + K++ + R++ KV +
Sbjct: 1881 VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISE 1940
Query: 1555 E 1555
E
Sbjct: 1941 E 1941
Score = 56.6 bits (135), Expect = 2e-07
Identities = 68/267 (25%), Positives = 124/267 (46%), Gaps = 44/267 (16%)
Query: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERN----ELRLNSDR----------------- 1286
++ + E + EI++LR+ LE+ E+ R EL S+R
Sbjct: 1676 QLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1735
Query: 1287 LESRISELTSELTD----ERNTGESASQLLD--AETAERLRAEKEMKELQTQYDALKKQM 1340
LE+ IS++ E+ D RN E A + + A AE L+ E ++ + +KK M
Sbjct: 1736 LETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKE---QDTSAHLERMKKNM 1792
Query: 1341 EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL-KYERAVREVDFTKKRLQQEFEDKLEV 1399
E ++ ++ RL A ++ + GG+ ++ K E VRE++ + E E K
Sbjct: 1793 E-QTVKDLQLRLDEAEQLALK------GGKKQIQKLEARVRELEG-----EVESEQKRNA 1840
Query: 1400 EQ-QNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1458
E + R+ ERR+ +L +EE ++ + +L+ +L A+++ K E + +++
Sbjct: 1841 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLA 1900
Query: 1459 KQRRFDSELSQAHEEAQREKLQREKLQ 1485
K R+ EL +A E A + Q KL+
Sbjct: 1901 KFRKLQHELEEAEERADIAESQVNKLR 1927
Score = 34.7 bits (78), Expect = 0.98
Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 6/143 (4%)
Query: 1210 KRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRS- 1268
++ ++DL +R + KG K KL VR L E ++ EQ RN E ++ LR
Sbjct: 1793 EQTVKDLQLRLDEAEQLALKGGKK-QIQKLEARVREL-EGEVESEQKRNA-EAVKGLRKH 1849
Query: 1269 --KLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEM 1326
++++ + E R N RL+ + +L +++ + E A + + A+ + + E+
Sbjct: 1850 ERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL 1909
Query: 1327 KELQTQYDALKKQMEVMEMEVME 1349
+E + + D + Q+ + ++ E
Sbjct: 1910 EEAEERADIAESQVNKLRVKSRE 1932
>gi|153792663 myosin, heavy chain 2, skeletal muscle, adult [Homo
sapiens]
Length = 1941
Score = 506 bits (1304), Expect = e-143
Identities = 428/1678 (25%), Positives = 814/1678 (48%), Gaps = 226/1678 (13%)
Query: 376 GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435
GKV VK + GA L V +D V N P D++ED+A + +L+E +VL+ L++RY A +++
Sbjct: 58 GKVTVKTE-GGATLTVKDDQVFPMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIY 116
Query: 436 TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495
TY+G + + P VY +V+ ++G +R++ PHI++++ AY+ ML R++QSI+
Sbjct: 117 TYSGLFCVTVNPYKWLPVYKPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176
Query: 496 LLGSSGSGKTTSCQHLVQYLATIA--------GISGNKVFSVEKWQALYT--LLEAFGNS 545
+ G SG+GKT + + ++QY ATIA I+ K+ + Q + LLEAFGN+
Sbjct: 177 ITGESGAGKTVNTKRVIQYFATIAVTGEKKKEEITSGKIQGTLEDQIISANPLLEAFGNA 236
Query: 546 PTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACG 605
T+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++++FY + +
Sbjct: 237 KTVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVVFQLKAERSYHIFYQITS-- 294
Query: 606 DGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKAC 662
+ EL L N + +++ E + +L A A+ +LG + +E+ +
Sbjct: 295 --NKKPELIEMLLITTNPYDYPFVSQGEISVASIDDQEELMATDSAIDILGFTNEEKVSI 352
Query: 663 WFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGT 722
+ + A+ H G ++ E + E A KAAYL + +L A+ + K G
Sbjct: 353 YKLTGAVMHYGNLKFKQKQREEQAEPDGT-EVADKAAYLQSLNSADLLKALCYPRVKVG- 410
Query: 723 LQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSL 782
+ +G + + G +A +Y ++F +V+ +N+ L + Q
Sbjct: 411 ---NEYVTKGQTVEQVSNAVG----------ALAKAVYEKMFLWMVARINQQLDTKQPRQ 457
Query: 783 CSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIEL 842
+ ++D GF+ + S E+LC N+T ++LQ+ F+ FV E E YK+E IE
Sbjct: 458 YFIGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEW 511
Query: 843 AFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLF 902
F D +D A+ L+ ++ G+ +LEEE + P A++ + +L+
Sbjct: 512 TFIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLY 556
Query: 903 SYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRL 961
+ + + Q P + K HF L H G V+YN+TGWL K +P + L
Sbjct: 557 DQHLGKSAN--FQKPKVVKGKAEAHFALIHYAGV--VDYNITGWLEKNK-DPLNETVVGL 611
Query: 962 LQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSL 1021
Q S K ++ LF G A G AG GG++ ++ S +T ++A+ +++L
Sbjct: 612 YQKSAMKTLAQLFSG----AQTAEGEGAG--GGAKKGGKKKGSSFQT----VSALFRENL 661
Query: 1022 CIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCE 1081
+ L+ ++ + HFV C +P +E P
Sbjct: 662 --------NKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA---- 689
Query: 1082 AGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYI 1141
++ L+ QLR + +L+ +R+ R+G+P +++++F++R+ VL +
Sbjct: 690 -----MEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ---- 740
Query: 1142 VVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRG 1201
+D ++A E+LL +D++ + G ++VFF+AG L LEE RD++ ++ +T QA CRG
Sbjct: 741 FIDSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDDKLAQLITRTQARCRG 800
Query: 1202 YLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE 1261
+LAR +++ + AI C+Q NI+ VK WPW KLF ++PL++ +E+++ E
Sbjct: 801 FLARVEYQRMVERREAIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKE 860
Query: 1262 EIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLR 1321
E Q+++ +L K+E +R EL L ++L ++ E A + D +++
Sbjct: 861 EFQKIKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQAEAEGLADAEERCDQLIKTKIQ 920
Query: 1322 AEKEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAVR 1380
E ++KE+ + A ++ E+ + +L +E+ ++DD + K E+
Sbjct: 921 LEAKIKEVTER--AEDEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEKH 975
Query: 1381 EVDFTKKRLQQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQ 1433
+ K L +E ++ + + K+ L ++ L DLQA+ ++ + L K
Sbjct: 976 ATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQAEEDK----VNTLTKAKI 1031
Query: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREKLQREKLQREKDM 1490
+L ++ D + LE ++ +LE+ +R+ + +L A E + + EK Q ++ ++K+
Sbjct: 1032 KLEQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESIMDIENEKQQLDEKLKKKEF 1091
Query: 1491 LLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAK 1550
E +L+ ++E++ +K+ L+A ++++ + + AS AK +KQ DL +
Sbjct: 1092 ---EISNLQSKIEDEQALGIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRE 1148
Query: 1551 VKDQEEELDEQAGT----IQM--------------LEQAKLRLEMEMERMRQTHSKEMES 1592
+++ E L+E G I+M LE+A L+ E +R+ H+ +
Sbjct: 1149 LEEISERLEEAGGATSAQIEMNKKREAEFQKMRRDLEEATLQHEATAATLRKKHADSVAE 1208
Query: 1593 RDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVN--RRD 1647
E++ + +Q +K+ +M++++++ + + V + K LE TL DQ++ +
Sbjct: 1209 LGEQIDNLQRVKQKLEKEKSEMKMEIDDLASNVETVSKAKGNLEKMCRTLEDQLSELKSK 1268
Query: 1648 FESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARK 1707
E ++RL DL + L + E + QL+E E + + ++
Sbjct: 1269 EEEQQRLINDLTAQRGRL----------------QTESGEFSRQLDEKEALVSQLSRGKQ 1312
Query: 1708 AMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVA 1767
A +IE+L Q+++ KAK AL L + + + ++ + EE+QE EL + A++
Sbjct: 1313 AFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQYEEEQESKAELQR----ALS 1368
Query: 1768 QASRDLAQ-----INDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEA 1822
+A+ ++AQ D + EE + K++L ++LQA + VE V+ S ++
Sbjct: 1369 KANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVE-----AVNAKCASLEKT 1423
Query: 1823 KIRELETRLEFERTQVKRLESLASRL---KENMEKLTEERDQRIAAENREKEQNKR---- 1875
K R L+ +E V+R + + L + N +K+ E Q+ + E E +++
Sbjct: 1424 KQR-LQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARS 1482
Query: 1876 ---------------------LQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAA 1914
L+R+ ++ ++E+ +L + AE ++ HELE + +E
Sbjct: 1483 LGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQE 1542
Query: 1915 NQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD---SELEDRVDGVK 1969
LQA L+ + +A++E E L ++ S+VD +E ++ +D +K
Sbjct: 1543 KCELQAALE-------EAEASLEHEEGKILRIQLELNQVKSEVDRKIAEKDEEIDQLK 1593
Score = 186 bits (471), Expect = 3e-46
Identities = 158/694 (22%), Positives = 330/694 (47%), Gaps = 61/694 (8%)
Query: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
E+ R ++++ +L+SK E+ ++ N+L RL++ E + +L DE+ SQL
Sbjct: 1252 EKMCRTLEDQLSELKSKEEEQQRLINDLTAQRGRLQTESGEFSRQL-DEKEA--LVSQLS 1308
Query: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
+ A + E+ ++L+ + A ++ + L+R ++ ++ E +
Sbjct: 1309 RGKQAFTQQIEELKRQLEEEIKAKNALAHALQSSRHDCDLLREQY----EEEQESKAELQ 1364
Query: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
+A EV + + + + + E ++ K++L +RL + E L+K
Sbjct: 1365 RALSKANTEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQAAEEHVEAVNAKCASLEKTK 1424
Query: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLL 1492
QRL E++D L +E L+KKQR FD L++ ++ + + E Q+E L
Sbjct: 1425 QRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQKCEETHAELEASQKEARSLG 1484
Query: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ---ESKDEASLAKVKKQLR---- 1545
E F +K EE + ++ +L+ E+ D++ Q K L K+KKQ+
Sbjct: 1485 TELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEGGKRIHELEKIKKQVEQEKC 1544
Query: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQ 1605
+L+A +++ E L+ + G I LR+++E+ +++ +++ +DEE+++ +++
Sbjct: 1545 ELQAALEEAEASLEHEEGKI-------LRIQLELNQVKSEVDRKIAEKDEEIDQLKRNHI 1597
Query: 1606 KKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALL 1665
+ ++ M+ L+ E + +R K+++EG L + Q+N + + + LR + + T+ +L
Sbjct: 1598 RIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMAAEALR-NYRNTQGIL 1656
Query: 1666 ADAQLMLDH-LKNSAPSKREIAQ-------LKNQLEESEFTCAAAVKARKAMEVEIED-- 1715
D Q+ LD L++ K ++A L+ ++EE T ++RK E E+ D
Sbjct: 1657 KDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDAS 1716
Query: 1716 -----LHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED----------MNELMK 1760
LH Q + K LE +S++Q E +I +E M E +K
Sbjct: 1717 ERVQLLHTQNTSLINTKKKLETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELK 1776
Query: 1761 KHK---AAVAQASRDLAQ-INDLQAQLEEA--------NKEKQELQEKLQALQSQVEFLE 1808
K + A + + +++ Q + DLQ +L+EA K+ Q+L+ +++ L+ +VE +
Sbjct: 1777 KEQDTSAHLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELEGEVESEQ 1836
Query: 1809 QSMVDK-SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAEN 1867
+ + + + E +++EL + E +R + RL+ L +L+ ++ + ++ N
Sbjct: 1837 KRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSN 1896
Query: 1868 REKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901
+ ++LQ +L + EE ++A + R K
Sbjct: 1897 TNLAKFRKLQHELEEA-EERADIAESQVNKLRVK 1929
Score = 103 bits (257), Expect = 2e-21
Identities = 124/598 (20%), Positives = 260/598 (43%), Gaps = 78/598 (13%)
Query: 1256 IRNKDEEIQQLRSKLEKA-EKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDA 1314
+R + EE Q+ +++L++A K E+ + E+ + T EL + + + +Q L A
Sbjct: 1349 LREQYEEEQESKAELQRALSKANTEVAQWRTKYETDAIQRTEELEEAK---KKLAQRLQA 1405
Query: 1315 ETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLK 1374
+ L+ L+ ++E + ++V AA + + D EW+ K
Sbjct: 1406 AEEHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERTNAACAALDKKQRNFDKILAEWKQK 1465
Query: 1375 YERAVREVDFTKKRLQ-------------QEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421
E E++ ++K + +E D+LE ++ + L++ + DL E
Sbjct: 1466 CEETHAELEASQKEARSLGTELFKIKNAYEESLDQLETLKRENKNLQQEISDLTEQIAEG 1525
Query: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481
+ + +L+K +++ E + + LE + E K R EL+Q E R+ ++
Sbjct: 1526 GKRIHELEKIKKQVEQEKCELQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAEK 1585
Query: 1482 EKLQREKDMLLAEAFSLKQQLEEK-DMDIAGFTQKV---VSLEAELQDISSQESKDEASL 1537
++ E D L + + ++ D +I + +E +L ++ Q +
Sbjct: 1586 DE---EIDQLKRNHIRIVESMQSTLDAEIRSRNDAIRLKKKMEGDLNEMEIQLNHANRMA 1642
Query: 1538 AKVKKQLRDLEAKVKDQEEELDEQAGT-------IQMLEQAKLRLEMEMERMRQTHSKEM 1590
A+ + R+ + +KD + LD+ + + M+E+ L+ E+E +R T +
Sbjct: 1643 AEALRNYRNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTE 1702
Query: 1591 ESR---DEEVEEARQSCQ-------------KKLKQMEVQLEEEYEDKQKVLREKRELEG 1634
SR ++E+ +A + Q KKL+ Q++ E ED +L+E R E
Sbjct: 1703 RSRKIAEQELLDASERVQLLHTQNTSLINTKKKLETDISQMQGEMED---ILQEARNAEE 1759
Query: 1635 KL-------ATLSDQVNRRDFESE--KRLRKDLKRTKALLADAQLMLDHLKNSAPS---- 1681
K A +++++ + S +R++K++++T + D QL LD + A
Sbjct: 1760 KAKKAITDAAMMAEELKKEQDTSAHLERMKKNMEQT---VKDLQLRLDEAEQLALKGGKK 1816
Query: 1682 -----KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSR 1736
+ + +L+ ++E + A AVK + E +++L Q ++ K L++ + +
Sbjct: 1817 QIQKLEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDK 1876
Query: 1737 LQREKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLA--QINDLQAQLEEAN 1787
LQ + + + EE +E N + K H+ A+ D+A Q+N L+ + E +
Sbjct: 1877 LQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVH 1934
Score = 81.6 bits (200), Expect = 7e-15
Identities = 68/301 (22%), Positives = 146/301 (48%), Gaps = 11/301 (3%)
Query: 1257 RNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAET 1316
RN ++ + L+ A + + +L+ +E R + L +E+ + R T E +
Sbjct: 1650 RNTQGILKDTQIHLDDALRSQEDLKEQLAMVERRANLLQAEIEELRATLEQTERSRKIAE 1709
Query: 1317 AERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD-DAGGEWRLKY 1375
E L A + ++ L TQ +L + +E ++ +++ GE++D K
Sbjct: 1710 QELLDASERVQLLHTQNTSLINTKKKLETDI--------SQMQGEMEDILQEARNAEEKA 1761
Query: 1376 ERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKKKCQR 1434
++A+ + + L++E + +E+ K+ +E+ + DLQ +E+++ AL+ KK+ Q+
Sbjct: 1762 KKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQK 1820
Query: 1435 LTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAE 1494
L A +++ + +E +Q RN E K R+ + + + + + ++ +LQ D L A+
Sbjct: 1821 LEARVRELEGEVESEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAK 1880
Query: 1495 AFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQ 1554
S K+Q EE + K L+ EL++ + E+ + K++ + R++ KV +
Sbjct: 1881 VKSYKRQAEEAEEQSNTNLAKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKVISE 1940
Query: 1555 E 1555
E
Sbjct: 1941 E 1941
Score = 56.6 bits (135), Expect = 2e-07
Identities = 68/267 (25%), Positives = 124/267 (46%), Gaps = 44/267 (16%)
Query: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERN----ELRLNSDR----------------- 1286
++ + E + EI++LR+ LE+ E+ R EL S+R
Sbjct: 1676 QLAMVERRANLLQAEIEELRATLEQTERSRKIAEQELLDASERVQLLHTQNTSLINTKKK 1735
Query: 1287 LESRISELTSELTD----ERNTGESASQLLD--AETAERLRAEKEMKELQTQYDALKKQM 1340
LE+ IS++ E+ D RN E A + + A AE L+ E ++ + +KK M
Sbjct: 1736 LETDISQMQGEMEDILQEARNAEEKAKKAITDAAMMAEELKKE---QDTSAHLERMKKNM 1792
Query: 1341 EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL-KYERAVREVDFTKKRLQQEFEDKLEV 1399
E ++ ++ RL A ++ + GG+ ++ K E VRE++ + E E K
Sbjct: 1793 E-QTVKDLQLRLDEAEQLALK------GGKKQIQKLEARVRELEG-----EVESEQKRNA 1840
Query: 1400 EQ-QNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1458
E + R+ ERR+ +L +EE ++ + +L+ +L A+++ K E + +++
Sbjct: 1841 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLA 1900
Query: 1459 KQRRFDSELSQAHEEAQREKLQREKLQ 1485
K R+ EL +A E A + Q KL+
Sbjct: 1901 KFRKLQHELEEAEERADIAESQVNKLR 1927
Score = 34.7 bits (78), Expect = 0.98
Identities = 33/143 (23%), Positives = 69/143 (48%), Gaps = 6/143 (4%)
Query: 1210 KRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRS- 1268
++ ++DL +R + KG K KL VR L E ++ EQ RN E ++ LR
Sbjct: 1793 EQTVKDLQLRLDEAEQLALKGGKK-QIQKLEARVREL-EGEVESEQKRNA-EAVKGLRKH 1849
Query: 1269 --KLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEM 1326
++++ + E R N RL+ + +L +++ + E A + + A+ + + E+
Sbjct: 1850 ERRVKELTYQTEEDRKNILRLQDLVDKLQAKVKSYKRQAEEAEEQSNTNLAKFRKLQHEL 1909
Query: 1327 KELQTQYDALKKQMEVMEMEVME 1349
+E + + D + Q+ + ++ E
Sbjct: 1910 EEAEERADIAESQVNKLRVKSRE 1932
>gi|114842389 myosin, heavy polypeptide 7B, cardiac muscle, beta [Homo
sapiens]
Length = 1983
Score = 506 bits (1302), Expect = e-142
Identities = 432/1676 (25%), Positives = 787/1676 (46%), Gaps = 206/1676 (12%)
Query: 346 WNETEKVWLVHRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCD 405
W+ ++VW+ + +++KSE G+V V+ D +L V E +++ N P D
Sbjct: 71 WDGKKRVWVPDEQDAYVEAEVKSEATG---GRVTVETK-DQKVLMVREAELQPMNPPRFD 126
Query: 406 RLEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGC 465
LED+A + +LNE+SVLH LRQRY +++TY+G + + P VY+ V+ +KG
Sbjct: 127 LLEDMAMMTHLNEASVLHNLRQRYARWMIYTYSGLFCVTINPYKWLPVYTASVVAAYKGK 186
Query: 466 RREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNK 525
RR D PHIYAVA AY ML +R +QS+++ G SG+GKT + + ++QY A +A +
Sbjct: 187 RRSDSPPHIYAVADNAYNDMLRNRDNQSMLITGESGAGKTVNTKRVIQYFAIVAALGDG- 245
Query: 526 VFSVEKWQALYT---------------LLEAFGNSPTIINGNATRFSQILSLDFDQAGQV 570
+K Q L T +EAFGN+ T+ N N++RF + + + F +G++
Sbjct: 246 --PGKKAQFLATKTGGTLEDQIIEANPAMEAFGNAKTLRNDNSSRFGKFIRIHFGPSGKL 303
Query: 571 ASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLN------HLAENNVF 624
ASA I + LLEK RV + E +++V+Y +L+ L+ L L+ H V
Sbjct: 304 ASADIDSYLLEKSRVIFQLPGERSYHVYYQILSGRKPELQDMLLLSMNPYDYHFCSQGVI 363
Query: 625 GIVPLAKPEEKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEA 684
+ + ++ AM +LG S DE+ AC+ I+ A+ H G K+
Sbjct: 364 TV-------DNMNDGEELIATDHAMDILGFSVDEKCACYKIVGALLHFGNM-KFKQKQRE 415
Query: 685 GRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGLGDGTGP 744
+ + E A KAAYL+G S +L + + R G E G
Sbjct: 416 EQAEADGTESADKAAYLMGVSSGDLLKGLLHPR-----------VRVGNEYVTKGQSVEQ 464
Query: 745 KLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQNPEQGGSARG 804
+ A+ L A Y LF LVS +N+ L + + ++D GF+ E
Sbjct: 465 VVFAVGAL---AKATYDRLFRWLVSRINQTLDTKLPRQFFIGVLDIAGFEIFEFN----- 516
Query: 805 ASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQ 864
SFE+LC N+T ++LQ+ F++ FV E E YK E I+ F D + +
Sbjct: 517 -SFEQLCINFTNEKLQQFFNQHMFVLEQEEYKREGIDWVFIDFGLDLQPCIDLI------ 569
Query: 865 SLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKP 924
++ G+L +LEEE + P AS+ + +L+ + + + + P
Sbjct: 570 ---------EKPLGILSILEEECMFPKASDASFRAKLYDNHAGKSPNFQQPRPDKKRKYQ 620
Query: 925 HHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVL 984
HF + H G V Y++ GWL K +P + + Q SQ ++++ L+ AGS
Sbjct: 621 AHFEVVHYAGV--VPYSIVGWLEKNK-DPLNETVVPIFQKSQNRLLATLYENYAGSC--- 674
Query: 985 SGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFV 1044
S + G + ++A S + ++ + K++L + L+ ++ ++ HFV
Sbjct: 675 --STEPPKSGVKEKRKKAASFQT-----VSQLHKENL--------NKLMTNLRATQPHFV 719
Query: 1045 HCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDA 1104
C +P G +D L+ QLR + +L+
Sbjct: 720 RCIVPNENKTPG-----------------------------VMDAFLVLHQLRCNGVLEG 750
Query: 1105 MRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCC 1164
+R+ RQG+P+ +++++FR+R+ +L P + +D R+A E+LL LDL+ +
Sbjct: 751 IRICRQGFPNRLLYTDFRQRYRILNPSAIP----DDTFMDSRKATEKLLGSLDLDHTQYQ 806
Query: 1165 MGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKN 1224
G ++VFF+AG L LEE RD++ ++ LTL QA RG L R +++ A+ +Q N
Sbjct: 807 FGHTKVFFKAGLLGVLEELRDQRLAKVLTLLQARSRGRLMRLEYQRLLGGRDALFTIQWN 866
Query: 1225 IKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNS 1284
I+ VK+W W KLF ++PL+ +EE++ E++ LR L AE +R EL
Sbjct: 867 IRAFNAVKNWSWMKLFFKMKPLLRSAQAEEELAALRAELRGLRGALAAAEAKRQELEETH 926
Query: 1285 DRLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVME 1344
+ ++L +L E++ A + +++ E ++KEL + L+ + EV
Sbjct: 927 VSITQEKNDLALQLQAEQDNLADAEERCHLLIKSKVQLEGKVKELS---ERLEDEEEVNA 983
Query: 1345 MEVMEARLI--RAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQ- 1401
R + E+ ++DD +L +A +E T+ +++ E+ +++
Sbjct: 984 DLAARRRKLEDECTELKKDIDD------LKLTLAKAEKEKQATENKVKNLTEEMAALDES 1037
Query: 1402 -----QNKRQL----ERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVR 1452
+ K+ L ++ LGDLQA+ + + L K RL +++D + LE ++
Sbjct: 1038 VARLTKEKKALQEAHQQALGDLQAEEDR----VSALTKAKLRLEQQVEDLECSLEQEKKL 1093
Query: 1453 NHELEKKQRRFDSELSQAHE---EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDI 1509
+ E+ +R+ + +L E +A ++K Q E+ ++KD +E L ++E++ +
Sbjct: 1094 RMDTERAKRKLEGDLKLTQESVADAAQDKQQLEEKLKKKD---SELSQLSLRVEDEQLLG 1150
Query: 1510 AGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTI---- 1565
A +K+ L+A +++ + + A+ A+V+KQ + ++++ E L+E G
Sbjct: 1151 AQMQKKIKELQARAEELEEELEAERAARARVEKQRAEAARELEELSERLEEAGGASAGQR 1210
Query: 1566 --------------QMLEQAKLRLEMEMERMRQTHSK---EMESRDEEVEEARQSCQKKL 1608
+ LE+A LR E + +R+ ++ E+ + + ++ RQ +K+
Sbjct: 1211 EGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQRVRQKLEKEK 1270
Query: 1609 KQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADA 1668
++ +++++ + + + R K E T DQ++ + E+ R+ LADA
Sbjct: 1271 SELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQ--------LADA 1322
Query: 1669 QLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKT 1728
L+ E +L LEE E + + + +E+L Q+++ +KAK+
Sbjct: 1323 STQRGRLQT------ESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKS 1376
Query: 1729 ALEEQLSRLQREKNEIQNRLEED---QEDMNELMKKHKAAVAQASRDLAQINDLQAQLEE 1785
AL + L+ + + ++ + EE+ Q ++ L+ K A VAQ R + + +Q + EE
Sbjct: 1377 ALAHAVQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQ-WRSKYEADAIQ-RTEE 1434
Query: 1786 ANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLA 1845
+ K++L +LQ + VE + S ++AK+R L+T E +++R S A
Sbjct: 1435 LEEAKKKLALRLQEAEEGVE-----AANAKCSSLEKAKLR-LQTESEDVTLELERATSAA 1488
Query: 1846 SRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELE 1905
+ L + L ++R E + + + QR+ R E+ L EA L+
Sbjct: 1489 AALDKKQRHLERALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLK 1548
Query: 1906 MDLESLEAANQSLQADLKLAFKRIGDLQ---AAIEDEMESDENEDLINSEGDSDVD 1958
+ ++L+ L + L+ K I +L+ A+E E +S+ L +EG +++
Sbjct: 1549 RENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEGE-KSEIQAALEEAEGALELE 1603
Score = 181 bits (460), Expect = 5e-45
Identities = 185/814 (22%), Positives = 366/814 (44%), Gaps = 72/814 (8%)
Query: 1147 RAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQ 1206
R +EEL E L+ + R L RL + +E R+ A R
Sbjct: 1190 RELEELSERLEEAGGASAGQREGCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGA 1249
Query: 1207 HFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQI-RNKDEEIQQ 1265
++ L + V++ ++K K L V L + S E++ R ++++ +
Sbjct: 1250 AELGEQVDSL--QRVRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSE 1307
Query: 1266 LRSKLEKAEKERNELRLNSDRLESRISELTSELTDERN---TGESASQLLDAETAERLRA 1322
+ K+E+ +++ + RL++ EL S L +E+ + S + L A++ E LR
Sbjct: 1308 AKIKVEELQRQLADASTQRGRLQTESGEL-SRLLEEKECLISQLSRGKALAAQSLEELRR 1366
Query: 1323 EKE------------MKELQTQYDALKKQMEVMEMEVMEARLIRA-AEINGEVDDDDAGG 1369
+ E ++ L+ D L++Q E E +A L R ++ N EV
Sbjct: 1367 QLEEESKAKSALAHAVQALRHDCDLLREQHE--EEAEAQAELQRLLSKANAEV------A 1418
Query: 1370 EWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLK 1429
+WR KYE + + E ++ K++L RL + + E + L+
Sbjct: 1419 QWRSKYEADAIQ--------------RTEELEEAKKKLALRLQEAEEGVEAANAKCSSLE 1464
Query: 1430 KKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKD 1489
K RL E +D L LE L+KKQR + L + + + + + E QRE
Sbjct: 1465 KAKLRLQTESEDVTLELERATSAAAALDKKQRHLERALEERRRQEEEMQRELEAAQRESR 1524
Query: 1490 MLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEA 1549
L E F L+ EE + ++ +L+ E+ D++ Q S S+ +++K + LE
Sbjct: 1525 GLGTELFRLRHGHEEALEALETLKRENKNLQEEISDLTDQVSLSGKSIQELEKTKKALEG 1584
Query: 1550 KVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLK 1609
+ + + L+E G +++ E LR+++E+ +++ +++ +DEE R++ Q+ ++
Sbjct: 1585 EKSEIQAALEEAEGALELEETKTLRIQLELSQVKAEVDRKLAEKDEECANLRRNHQRAVE 1644
Query: 1610 QMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV---NRRDFESE---KRLRKDLKRTKA 1663
++ L+ E + + LR K+++EG L L Q+ R+ E++ + ++ LK +A
Sbjct: 1645 SLQASLDAETRARNEALRLKKKMEGDLNDLELQLGHATRQATEAQAATRLMQAQLKEEQA 1704
Query: 1664 LLADAQLMLDHLKNSAPS-KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDD 1722
+ Q + L A + +R + L +LEE ++R+ E E+ + +++
Sbjct: 1705 GRDEEQRLAAELHEQAQALERRASLLAAELEELRAALEQGERSRRLAEQELLEATERLNL 1764
Query: 1723 IAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQA---SRDLAQINDL 1779
+ T L Q +L+ + ++ +EE ++ E +K K A+ A + +L + D
Sbjct: 1765 LHSQNTGLLNQKKKLEADLAQLSGEVEEAAQERREAEEKAKKAITDAAMMAEELKKEQDT 1824
Query: 1780 QAQLEEANKEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELETRLEFE--- 1834
A LE + K+ L++ ++ LQ+++E EQ+ + K V + EAK+RELE L+ E
Sbjct: 1825 SAHLE---RMKKTLEQTVRELQARLEEAEQAALRGGKKQVQKLEAKVRELEAELDAEQKK 1881
Query: 1835 --------RTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEE 1886
R +R++ LA + +E+ + L +D ++ + + K +RQ + +++
Sbjct: 1882 HAEALKGVRKHERRVKELAYQAEEDRKNLARMQD----LVDKLQSKVKSYKRQFEEAEQQ 1937
Query: 1887 MGELARKEAEASRKKHELEMDLESLEAANQSLQA 1920
K +A + + E + E L+A
Sbjct: 1938 ANTNLAKYRKAQHELDDAEERADMAETQANKLRA 1971
Score = 146 bits (368), Expect = 2e-34
Identities = 207/894 (23%), Positives = 381/894 (42%), Gaps = 136/894 (15%)
Query: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGES 1307
+++L++E + + ++ QQL KL+K + E ++L L + + +++ ++ + + E
Sbjct: 1107 DLKLTQESVADAAQDKQQLEEKLKKKDSELSQLSLRVEDEQLLGAQMQKKIKELQARAEE 1166
Query: 1308 ASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDA 1367
+ L+AE A R R EK+ E + + L +++E +A
Sbjct: 1167 LEEELEAERAARARVEKQRAEAARELEELSERLE------------------------EA 1202
Query: 1368 GGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES----QR 1423
GG + E R+ + RL++E E+ + L R+ + A+ E QR
Sbjct: 1203 GGASAGQRE-GCRKREAELGRLRRELEEAALRHEATVAALRRKQAEGAAELGEQVDSLQR 1261
Query: 1424 ALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREK 1483
Q+L+K+ L E+ D ++E EK R ++ +LS+A + + + Q
Sbjct: 1262 VRQKLEKEKSELRMEVDDLAANVETLTRAKASAEKLCRTYEDQLSEAKIKVEELQRQLAD 1321
Query: 1484 LQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ---ESKDEASLAKV 1540
++ L E+ L + LEEK+ I+ ++ L+++ Q ESK +++LA
Sbjct: 1322 ASTQRGRLQTESGELSRLLEEKECLISQLSRGKALAAQSLEELRRQLEEESKAKSALAHA 1381
Query: 1541 KKQLR-DLEAKVKDQEEELDEQAGTIQML-----EQAKLRLEMEMERMRQTHSKE----- 1589
+ LR D + + EEE + QA ++L E A+ R + E + +++T E
Sbjct: 1382 VQALRHDCDLLREQHEEEAEAQAELQRLLSKANAEVAQWRSKYEADAIQRTEELEEAKKK 1441
Query: 1590 ----MESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVL-----------REKRELEG 1634
++ +E VE A C L++ +++L+ E ED L +++R LE
Sbjct: 1442 LALRLQEAEEGVEAANAKCSS-LEKAKLRLQTESEDVTLELERATSAAAALDKKQRHLER 1500
Query: 1635 KLATLSDQVN--RRDFESEKR----LRKDLKRTKALLADAQLMLDHLKNSAPS-KREIAQ 1687
L Q +R+ E+ +R L +L R + +A L+ LK + + EI+
Sbjct: 1501 ALEERRRQEEEMQRELEAAQRESRGLGTELFRLRHGHEEALEALETLKRENKNLQEEISD 1560
Query: 1688 LKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE----KNE 1743
L +Q+ S + K +KA+E E ++ +++ A E + R+Q E K E
Sbjct: 1561 LTDQVSLSGKSIQELEKTKKALEGEKSEIQAALEEAEGALELEETKTLRIQLELSQVKAE 1620
Query: 1744 IQNRLEEDQEDMNELMKKHKAAVA--QASRDL----------------AQINDLQAQLEE 1785
+ +L E E+ L + H+ AV QAS D +NDL+ QL
Sbjct: 1621 VDRKLAEKDEECANLRRNHQRAVESLQASLDAETRARNEALRLKKKMEGDLNDLELQLGH 1680
Query: 1786 ANKEKQELQEKLQALQSQV---------------EFLEQSMVDKSLVSRQEAKIRELETR 1830
A ++ E Q + +Q+Q+ E EQ+ + S A++ EL
Sbjct: 1681 ATRQATEAQAATRLMQAQLKEEQAGRDEEQRLAAELHEQAQALERRASLLAAELEELRAA 1740
Query: 1831 LEFERTQVKRLESLASR-LKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGE 1889
LE Q +R LA + L E E+L Q N Q K+L+ L E+ E
Sbjct: 1741 LE----QGERSRRLAEQELLEATERLNLLHSQNTGLLN----QKKKLEADLAQLSGEVEE 1792
Query: 1890 LA--RKEAEASRKK---------HELEMDLES---LEAANQSLQADLKLAFKRIGDL-QA 1934
A R+EAE KK EL+ + ++ LE ++L+ ++ R+ + QA
Sbjct: 1793 AAQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKTLEQTVRELQARLEEAEQA 1852
Query: 1935 AIEDEMESDENEDLINSEGDSDVDSELE---DRVDGVKSWLSKNKGPSKAASDDGSLKS- 1990
A+ + + + E ++++D+E + + + GV+ + K + A +D +
Sbjct: 1853 ALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLAR 1912
Query: 1991 -----SSPTSYWKSLAPDRSDDEHDPLDNTSRPRYSHSYLSDSDTEAKLTETNA 2039
S KS + E N ++ R + L D++ A + ET A
Sbjct: 1913 MQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQA 1966
Score = 86.3 bits (212), Expect = 3e-16
Identities = 77/303 (25%), Positives = 146/303 (48%), Gaps = 23/303 (7%)
Query: 1246 LIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTG 1305
L++ QL EEQ +DEE Q+L ++L + + LE R S L +EL + R
Sbjct: 1694 LMQAQLKEEQA-GRDEE-QRLAAELHE----------QAQALERRASLLAAELEELRAAL 1741
Query: 1306 ESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD 1365
E + E L A + + L +Q L Q + +E ++ A+++GEV++
Sbjct: 1742 EQGERSRRLAEQELLEATERLNLLHSQNTGLLNQKKKLEADL--------AQLSGEVEEA 1793
Query: 1366 -DAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES-QR 1423
E K ++A+ + + L++E + +E+ K+ LE+ + +LQA EE+ Q
Sbjct: 1794 AQERREAEEKAKKAITDAAMMAEELKKEQDTSAHLERM-KKTLEQTVRELQARLEEAEQA 1852
Query: 1424 ALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREK 1483
AL+ KK+ Q+L A++++ + L+ +Q ++ E K R+ + + + +A+ ++ +
Sbjct: 1853 ALRGGKKQVQKLEAKVRELEAELDAEQKKHAEALKGVRKHERRVKELAYQAEEDRKNLAR 1912
Query: 1484 LQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQ 1543
+Q D L ++ S K+Q EE + K + EL D + E K++ +
Sbjct: 1913 MQDLVDKLQSKVKSYKRQFEEAEQQANTNLAKYRKAQHELDDAEERADMAETQANKLRAR 1972
Query: 1544 LRD 1546
RD
Sbjct: 1973 TRD 1975
>gi|153945790 myosin, heavy chain 8, skeletal muscle, perinatal [Homo
sapiens]
Length = 1937
Score = 502 bits (1293), Expect = e-141
Identities = 434/1724 (25%), Positives = 813/1724 (47%), Gaps = 239/1724 (13%)
Query: 320 WLRSGEGPRRE----PSDAKTEEQIAAEEAWNETEKVWLVHRDGFSLASQLKSEELNLPE 375
+LR E R E P DAKT +A + S +KS +
Sbjct: 18 YLRKSEKERIEAQNKPFDAKTSVFVAEPKE------------------SYVKSTIQSKEG 59
Query: 376 GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435
GKV VK + GA L V ED V N P D++ED+A + +L+E VL+ L++RY A +++
Sbjct: 60 GKVTVKTE-GGATLTVREDQVFPMNPPKYDKIEDMAMMTHLHEPGVLYNLKERYAAWMIY 118
Query: 436 TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495
TY+G + + P VY +V+ ++G +R++ PHI++++ AY+ ML R++QSI+
Sbjct: 119 TYSGLFCVTVNPYKWLPVYKPEVVAAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 178
Query: 496 LLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQ--------ALYTLLEAFGNSPT 547
+ G SG+GKT + + ++QY ATIA K K Q + LLEAFGN+ T
Sbjct: 179 ITGESGAGKTVNTKRVIQYFATIAVTGEKKKDESGKMQGTLEDQIISANPLLEAFGNAKT 238
Query: 548 IINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGDG 607
+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++++FY + +
Sbjct: 239 VRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQITS---- 294
Query: 608 TLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKACWF 664
+ +L L N + +++ E + +L A A+ +LG +P+E+ + +
Sbjct: 295 NKKPDLIEMLLITTNPYDYAFVSQGEITVPSIDDQEELMATDSAIDILGFTPEEKVSIYK 354
Query: 665 ILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTLQ 724
+ A+ H G ++ E + E A KAAYL + +L A+ + K G
Sbjct: 355 LTGAVMHYGNMKFKQKQREEQAEPDGT-EVADKAAYLQSLNSADLLKALCYPRVKVG--- 410
Query: 725 RSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLCS 784
+ +G + + G +A +Y ++F +V+ +N+ L + Q
Sbjct: 411 -NEYVTKGQTVQQVYNAVG----------ALAKAVYEKMFLWMVTRINQQLDTKQPRQYF 459
Query: 785 MMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELAF 844
+ ++D GF+ + S E+LC N+T ++LQ+ F+ FV E E YK+E IE F
Sbjct: 460 IGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWTF 513
Query: 845 DDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFSY 904
D +D A+ L+ ++ G+ +LEEE + P A++ + +L+
Sbjct: 514 IDF---------GMDLAACIELI------EKPLGIFSILEEECMFPKATDTSFKNKLYDQ 558
Query: 905 YGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQ 963
+ + + Q P + K HF L H GT V+YN+TGWL+ K +P L Q
Sbjct: 559 HLGKSAN--FQKPKVVKGKAEAHFSLIHYAGT--VDYNITGWLDKNK-DPLNDTVVGLYQ 613
Query: 964 DSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLCI 1023
S K +++LF + A E S A + A +F T A ++
Sbjct: 614 KSAMKTLASLF-----------STYASAEADSS-AKKGAKKKGSSFQTVSALFRE----- 656
Query: 1024 QMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEAG 1083
++ L+ ++ + HFV C +P +E P
Sbjct: 657 ----NLNKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA------ 686
Query: 1084 LLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVV 1143
++ L+ QLR + +L+ +R+ R+G+P +++ +F++R+ VL + +
Sbjct: 687 ---MEHELVLHQLRCNGVLEGIRICRKGFPSRILYGDFKQRYKVLNASAIPEGQ----FI 739
Query: 1144 DERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYL 1203
D ++A E+LL +D++ + G ++VFF+AG L LEE RDE+ ++ +T QA CRG+L
Sbjct: 740 DSKKASEKLLASIDIDHTQYKFGHTKVFFKAGLLGLLEEMRDEKLAQIITRTQAVCRGFL 799
Query: 1204 ARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEI 1263
R ++K + A+ C+Q N++ VK WPW KLF ++PL++ +E+++ EE
Sbjct: 800 MRVEYQKMLQRREALFCIQYNVRAFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEEF 859
Query: 1264 QQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLRAE 1323
Q+ + +L K+E +R EL L ++L ++ E ++ A + + +++ E
Sbjct: 860 QKTKDELAKSEAKRKELEEKMVTLLKEKNDLQLQVQSEADSLADAEERCEQLIKNKIQLE 919
Query: 1324 KEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAVREV 1382
++KE+ + A +++ E+ + +L +E+ ++DD + K E+
Sbjct: 920 AKIKEVTER--AEEEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEKHAT 974
Query: 1383 DFTKKRLQQE---FEDKLEVEQQNKRQL----ERRLGDLQADSEESQRALQQLKKKCQRL 1435
+ K L +E ++ + + K+ L ++ L DLQA+ ++ + L K +L
Sbjct: 975 ENKVKNLTEEMAGLDETIAKLSKEKKALQETHQQTLDDLQAEEDK----VNILTKAKTKL 1030
Query: 1436 TAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEA 1495
++ D + LE ++ +LE+ +R+ + +L A E + +++L + + E
Sbjct: 1031 EQQVDDLEGSLEQEKKLRMDLERAKRKLEGDLKLAQESTMDMENDKQQLDEKLEKKEFEI 1090
Query: 1496 FSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQE 1555
+L ++E++ +K+ L+A ++++ + + AS AK +KQ DL ++++
Sbjct: 1091 SNLISKIEDEQAVEIQLQKKIKELQARIEELGEEIEAERASRAKAEKQRSDLSRELEEIS 1150
Query: 1556 EELDEQAGTIQM------------------LEQAKLRLEMEMERMRQTHSKEMESRDEEV 1597
E L+E G LE+A L+ E + +R+ H+ M E++
Sbjct: 1151 ERLEEAGGATSAQVELNKKREAEFQKLRRDLEEATLQHEAMVAALRKKHADSMAELGEQI 1210
Query: 1598 ---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVN--RRDFESEK 1652
+ +Q +K+ +++++ ++ + + + + K LE +L DQV+ + E ++
Sbjct: 1211 DNLQRVKQKLEKEKSELKMETDDLSSNAEAISKAKGNLEKMCRSLEDQVSELKTKEEEQQ 1270
Query: 1653 RLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVE 1712
RL DL +A L + E + QL+E + + ++++A +
Sbjct: 1271 RLINDLTAQRARL----------------QTEAGEYSRQLDEKDALVSQLSRSKQASTQQ 1314
Query: 1713 IEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL---MKKHKAAVAQ- 1768
IE+L Q+++ KAK AL L + + + ++ + EE+QE EL + K + VAQ
Sbjct: 1315 IEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALSKANSEVAQW 1374
Query: 1769 -----------------ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQSQVEFL--- 1807
A + LAQ + + + +E N + L++ Q LQ++VE L
Sbjct: 1375 RTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQRLQNEVEDLMLD 1434
Query: 1808 -------------EQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEK 1854
+Q DK L E K + ET+ E E +Q K SL++ L +
Sbjct: 1435 VERSNAACAALDKKQRNFDKVL---SEWKQKYEETQAELEASQ-KESRSLSTELFKVKNV 1490
Query: 1855 LTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAA 1914
E DQ + +NK LQ+++ D E++ E ++ E + K ++E + ++AA
Sbjct: 1491 YEESLDQL----ETLRRENKNLQQEISDLTEQIAEGGKQIHELEKIKKQVEQEKCEIQAA 1546
Query: 1915 NQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD 1958
+ +A L+ +I +Q + ++++S+ + + +E D ++D
Sbjct: 1547 LEEAEASLEHEEGKILRIQLEL-NQVKSEVDRKI--AEKDEEID 1587
Score = 189 bits (479), Expect = 3e-47
Identities = 171/709 (24%), Positives = 338/709 (47%), Gaps = 91/709 (12%)
Query: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDE--------RNT 1304
E+ R+ ++++ +L++K E+ ++ N+L RL++ E + +L ++ R+
Sbjct: 1249 EKMCRSLEDQVSELKTKEEEQQRLINDLTAQRARLQTEAGEYSRQLDEKDALVSQLSRSK 1308
Query: 1305 GESASQL------LDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AE 1357
S Q+ L+ ET + ++ + D L++Q E E + +A L RA ++
Sbjct: 1309 QASTQQIEELKHQLEEETKAKNALAHALQSSRHDCDLLREQYE--EEQEGKAELQRALSK 1366
Query: 1358 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 1417
N EV +WR KYE + + E ++ K++L +RL + +
Sbjct: 1367 ANSEV------AQWRTKYETDAIQ--------------RTEELEEAKKKLAQRLQEAEEH 1406
Query: 1418 SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQRE 1477
E L+K QRL E++D L +E L+KKQR FD LS+ ++ +
Sbjct: 1407 VEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQKYEET 1466
Query: 1478 KLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ---ESKDE 1534
+ + E Q+E L E F +K EE + ++ +L+ E+ D++ Q K
Sbjct: 1467 QAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAEGGKQI 1526
Query: 1535 ASLAKVKKQLR----DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEM 1590
L K+KKQ+ +++A +++ E L+ + G I LR+++E+ +++ +++
Sbjct: 1527 HELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKI-------LRIQLELNQVKSEVDRKI 1579
Query: 1591 ESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFES 1650
+DEE+++ +++ + ++ M+ L+ E + LR K+++EG L + Q+N + +
Sbjct: 1580 AEKDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLA 1639
Query: 1651 EKRLRKDLKRTKALLADAQLMLDH-LKNSAPSKREIA-------QLKNQLEESEFTCAAA 1702
+ LR + + T+ +L + QL LD L+ K ++A L+ ++EE T
Sbjct: 1640 AESLR-NYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQT 1698
Query: 1703 VKARKAMEVEIED-------LHLQIDDIAKAKTALEEQLSRLQREKNEI--QNRLEE--- 1750
++RK E E+ D LH Q + K LE +S+LQ E E+ ++R E
Sbjct: 1699 ERSRKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVIQESRNAEEKA 1758
Query: 1751 -----DQEDMNELMKKHK---AAVAQASRDLAQ-INDLQAQLEEA--------NKEKQEL 1793
D M E +KK + A + + ++L Q + DLQ +L+EA K+ Q+L
Sbjct: 1759 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKL 1818
Query: 1794 QEKLQALQSQVEFLEQSMVDK-SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENM 1852
+ +++ L+ +VE ++ + + + E +++EL + E +R V RL+ L +L+ +
Sbjct: 1819 EARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQAKV 1878
Query: 1853 EKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKK 1901
+ + ++ N + ++LQ +L + EE ++A + R K
Sbjct: 1879 KSYKRQAEEAEEQSNANLSKFRKLQHELEEA-EERADIAESQVNKLRVK 1926
Score = 99.0 bits (245), Expect = 4e-20
Identities = 124/596 (20%), Positives = 263/596 (44%), Gaps = 74/596 (12%)
Query: 1256 IRNKDEEIQQLRSKLEKA-EKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDA 1314
+R + EE Q+ +++L++A K +E+ + E+ + T EL + + + A +L +A
Sbjct: 1346 LREQYEEEQEGKAELQRALSKANSEVAQWRTKYETDAIQRTEELEEAKK--KLAQRLQEA 1403
Query: 1315 ETAERLRA-EKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL 1373
E E + A + L+ L+ ++E + ++V + AA + + D EW+
Sbjct: 1404 E--EHVEAVNAKCASLEKTKQRLQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQ 1461
Query: 1374 KYERAVREVD-------------FTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEE 1420
KYE E++ F K + +E D+LE ++ + L++ + DL E
Sbjct: 1462 KYEETQAELEASQKESRSLSTELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIAE 1521
Query: 1421 SQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQ 1480
+ + +L+K +++ E + + LE + E K R EL+Q E R+ +
Sbjct: 1522 GGKQIHELEKIKKQVEQEKCEIQAALEEAEASLEHEEGKILRIQLELNQVKSEVDRKIAE 1581
Query: 1481 R-EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAK 1539
+ E++ + K +++ L+ + + +E +L ++ Q + A+
Sbjct: 1582 KDEEIDQLKRNHTRVVETMQSTLDAEIRSRNDALRVKKKMEGDLNEMEIQLNHANRLAAE 1641
Query: 1540 VKKQLRDLEAKVKDQEEELDEQAG-------TIQMLEQAKLRLEMEMERMRQTHSKEMES 1592
+ R+ + +K+ + LD+ + ++E+ L+ E+E + T + S
Sbjct: 1642 SLRNYRNTQGILKETQLHLDDALRGQEDLKEQLAIVERRANLLQAEIEELWATLEQTERS 1701
Query: 1593 R---DEEVEEARQSCQ-------------KKLKQMEVQLEEEYEDKQKVLREKRELEGKL 1636
R ++E+ +A + Q KKL+ QL+ E E+ V++E R E K
Sbjct: 1702 RKIAEQELLDASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEE---VIQESRNAEEKA 1758
Query: 1637 -------ATLSDQVNRRDFESE--KRLRKDLKRTKALLADAQLMLDHLKNSAPS------ 1681
A +++++ + S +R++K+L++T + D Q LD + A
Sbjct: 1759 KKAITDAAMMAEELKKEQDTSAHLERMKKNLEQT---VKDLQHRLDEAEQLALKGGKKQI 1815
Query: 1682 ---KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQ 1738
+ + +L+ ++E + A AVK + E +++L Q ++ K L++ + +LQ
Sbjct: 1816 QKLEARVRELEGEVENEQKRNAEAVKGLRKHERRVKELTYQTEEDRKNVLRLQDLVDKLQ 1875
Query: 1739 REKNEIQNRLEEDQEDMNELMKK-----HKAAVAQASRDLA--QINDLQAQLEEAN 1787
+ + + EE +E N + K H+ A+ D+A Q+N L+ + E +
Sbjct: 1876 AKVKSYKRQAEEAEEQSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVH 1931
Score = 88.2 bits (217), Expect = 7e-17
Identities = 133/648 (20%), Positives = 277/648 (42%), Gaps = 107/648 (16%)
Query: 1158 LEKSSCCMGLSRVFFRAGTLARLEE---------QRDEQTSRNLTLFQAACRGYLARQHF 1208
L K++ + R + + R EE QR ++ ++ A C +
Sbjct: 1364 LSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQEAEEHVEAVNAKCASLEKTKQR 1423
Query: 1209 KKRKIQDLAI-------RCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDE 1261
+ +++DL + C + K+ K WK E++ S+++ R+
Sbjct: 1424 LQNEVEDLMLDVERSNAACAALDKKQRNFDKVLSEWKQ-KYEETQAELEASQKESRSLST 1482
Query: 1262 EIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERLR 1321
E+ ++++ E++ + LR + L+ IS+LT ++ E Q+ + E ++ +
Sbjct: 1483 ELFKVKNVYEESLDQLETLRRENKNLQQEISDLTEQIA------EGGKQIHELEKIKK-Q 1535
Query: 1322 AEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVD-----DDDAGGEWRLKYE 1376
E+E E+Q + + +E E +++ +L ++ EVD D+ + + +
Sbjct: 1536 VEQEKCEIQAALEEAEASLEHEEGKILRIQL-ELNQVKSEVDRKIAEKDEEIDQLKRNHT 1594
Query: 1377 RAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT 1436
R V + T + D L V K+++E L +++ + R + + +
Sbjct: 1595 RVVETMQSTLDAEIRSRNDALRV----KKKMEGDLNEMEIQLNHANRLAAESLRNYRNTQ 1650
Query: 1437 AELQDTKLHLE----GQQVRNHELEKKQRRFDSELSQAHEE---AQREKLQREKLQREKD 1489
L++T+LHL+ GQ+ +L +RR + L QA E A E+ +R + E++
Sbjct: 1651 GILKETQLHLDDALRGQEDLKEQLAIVERR--ANLLQAEIEELWATLEQTERSRKIAEQE 1708
Query: 1490 MLLAEAFSLKQQLEEKDMDIAGFTQK----VVSLEAELQDISSQESKDEASLAKVKKQLR 1545
+L +A Q L ++ + +K V L++E++++ QES++ K KK +
Sbjct: 1709 LL--DASERVQLLHTQNTSLINTKKKLENDVSQLQSEVEEVI-QESRNAEE--KAKKAIT 1763
Query: 1546 DLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEE-ARQSC 1604
D EEL ++ T LE+ K LE + K+++ R +E E+ A +
Sbjct: 1764 DAAMMA----EELKKEQDTSAHLERMKKNLEQTV--------KDLQHRLDEAEQLALKGG 1811
Query: 1605 QKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKAL 1664
+K+++++E ++ RELEG++ + +R+ E+ K LRK +R K L
Sbjct: 1812 KKQIQKLEARV--------------RELEGEV----ENEQKRNAEAVKGLRKHERRVKEL 1853
Query: 1665 LADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIA 1724
+ ++ + +L++ +++ + A VK+ K E E+
Sbjct: 1854 TYQTE----------EDRKNVLRLQDLVDKLQ----AKVKSYKRQAEEAEE--------- 1890
Query: 1725 KAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRD 1772
A + +LQ E E + R + + +N+L K + + S +
Sbjct: 1891 -QSNANLSKFRKLQHELEEAEERADIAESQVNKLRVKSREVHTKISAE 1937
>gi|98986453 myosin, heavy chain 3, skeletal muscle, embryonic [Homo
sapiens]
Length = 1940
Score = 502 bits (1292), Expect = e-141
Identities = 430/1673 (25%), Positives = 815/1673 (48%), Gaps = 222/1673 (13%)
Query: 375 EGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLL 434
+GKV V+ + D L V +DV N P DR+ED+A L +LNE +VL+ L+ RY + ++
Sbjct: 57 DGKVTVETE-DNRTLVVKPEDVYAMNPPKFDRIEDMAMLTHLNEPAVLYNLKDRYTSWMI 115
Query: 435 HTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSI 494
+TY+G + + P VY+ +V+ ++G +R++ PHI++++ AY+ ML R++QSI
Sbjct: 116 YTYSGLFCVTVNPYKWLPVYNPEVVEGYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSI 175
Query: 495 ILLGSSGSGKTTSCQHLVQYLATIAGISG------NKVFSVEKWQALYT--LLEAFGNSP 546
++ G SG+GKT + + ++QY ATIA +K+ + Q + LLEAFGN+
Sbjct: 176 LITGESGAGKTVNTKRVIQYFATIAATGDLAKKKDSKMKGTLEDQIISANPLLEAFGNAK 235
Query: 547 TIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLACGD 606
T+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++++FY +L+
Sbjct: 236 TVRNDNSSRFGKFIRIHFGTTGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILS--- 292
Query: 607 GTLRTELHLNHLAENNVFGIVPLAKPEEKQKA---AQQFSKLQAAMKVLGISPDEQKACW 663
+ EL L N + +++ E + A++ +A+ +LG +P+E+ +
Sbjct: 293 -NKKPELIELLLITTNPYDYPFISQGEILVASIDDAEELLATDSAIDILGFTPEEKSGLY 351
Query: 664 FILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGGTL 723
+ A+ H G ++ E + E A K AYL+G + +L A+ + K G
Sbjct: 352 KLTGAVMHYGNMKFKQKQREEQAEPDGT-EVADKTAYLMGLNSSDLLKALCFPRVKVGN- 409
Query: 724 QRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHSLC 783
E G A+ L + +Y +LF +V+ +N+ L +
Sbjct: 410 ----------EYVTKGQTVDQVHHAVNAL---SKSVYEKLFLWMVTRINQQLDTKLPRQH 456
Query: 784 SMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIELA 843
+ ++D GF+ E S E+LC N+T ++LQ+ F+ FV E E YK+E IE
Sbjct: 457 FIGVLDIAGFEIFEYN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIEWT 510
Query: 844 FDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERLFS 903
F D +D A+ L+ ++ G+ +LEEE + P A++ + +L+
Sbjct: 511 FIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKLYD 555
Query: 904 YY-GPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPRLL 962
+ G +K + ++ HF L H GT V+Y+V+GWL K +P + L
Sbjct: 556 QHLGKSNNFQKPK--VVKGRAEAHFSLIHYAGT--VDYSVSGWLEKNK-DPLNETVVGLY 610
Query: 963 QDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKSLC 1022
Q S +++++L+ A AT + S G ++A ++ +S + ++A+ +++L
Sbjct: 611 QKSSNRLLAHLY---ATFATADADS-----GKKKVAKKKGSSFQT-----VSALFRENL- 656
Query: 1023 IQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHCEA 1082
+ L+ ++ + HFV C +P +E P
Sbjct: 657 -------NKLMSNLRTTHPHFVRCIIP--------------------NETKTPGA----- 684
Query: 1083 GLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIV 1142
++ L+ QLR + +L+ +R+ R+G+P+ +++ +F++R+ VL +
Sbjct: 685 ----MEHSLVLHQLRCNGVLEGIRICRKGFPNRILYGDFKQRYRVLNASAIPEGQ----F 736
Query: 1143 VDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGY 1202
+D ++A E+LL +D++ + G ++VFF+AG L LEE RD++ ++ +T QA CRG+
Sbjct: 737 IDSKKACEKLLASIDIDHTQYKFGHTKVFFKAGLLGTLEEMRDDRLAKLITRTQAVCRGF 796
Query: 1203 LARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEE 1262
L R F+K + +I C+Q NI+ VK WPW KLF ++PL++ +E+++ EE
Sbjct: 797 LMRVEFQKMVQRRESIFCIQYNIRSFMNVKHWPWMKLFFKIKPLLKSAETEKEMATMKEE 856
Query: 1263 IQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDER----NTGESASQLLDA---- 1314
Q+ + +L K+E +R EL L ++L ++ E + E QL+ A
Sbjct: 857 FQKTKDELAKSEAKRKELEEKLVTLVQEKNDLQLQVQAESENLLDAEERCDQLIKAKFQL 916
Query: 1315 -----ETAERLRAEKEMK-ELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAG 1368
E ER E+E+ EL + L+ + ++ ++ + L A +V+ +
Sbjct: 917 EAKIKEVTERAEDEEEINAELTAKKRKLEDECSELKKDIDDLELTLA-----KVEKEKHA 971
Query: 1369 GEWRLK-YERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQ 1427
E ++K + +D T +L +E + E QQ L DLQA+ ++ +
Sbjct: 972 TENKVKNLTEELSGLDETIAKLTREKKALQEAHQQ-------ALDDLQAEEDK----VNS 1020
Query: 1428 LKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE---EAQREKLQREKL 1484
L K +L +++D + LE ++ +LE+ +R+ + +L A E + + +K Q ++
Sbjct: 1021 LNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESILDLENDKQQLDER 1080
Query: 1485 QREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQL 1544
++KD E L+ ++E++ F +K+ L+A ++++ + + A+ AK +KQ
Sbjct: 1081 LKKKDF---EYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAERATRAKTEKQR 1137
Query: 1545 RDLEAKVKDQEEELDEQAGTIQM------------------LEQAKLRLEMEMERMRQTH 1586
D ++++ E L+E G LE+A L+ E + +R+ H
Sbjct: 1138 SDYARELEELSERLEEAGGVTSTQIELNKKREAEFLKLRRDLEEATLQHEAMVAALRKKH 1197
Query: 1587 SKEMESRDEEV---EEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV 1643
+ + E++ + +Q +K+ + ++++++ + V + K LE TL DQ+
Sbjct: 1198 ADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKANLEKICRTLEDQL 1257
Query: 1644 NRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAV 1703
+ ++E +++R+ + L + L + E +L QLEE E +
Sbjct: 1258 SEARGKNE-----EIQRSLSELTTQKSRL---------QTEAGELSRQLEEKESIVSQLS 1303
Query: 1704 KARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL---MK 1760
++++A + E+L Q+++ KAK AL L + + + ++ + EE+QE EL +
Sbjct: 1304 RSKQAFTQQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYEEEQEGKAELQRALS 1363
Query: 1761 KHKAAVAQ------------------ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQ 1801
K + VAQ A + LAQ + D + Q+E N + L++ Q LQ
Sbjct: 1364 KANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKTKQRLQ 1423
Query: 1802 SQVEFLEQSMVD----KSLVSRQEAKIRELETRLEFERTQVKRLES-LASRLKENMEKLT 1856
+VE L MVD SL + + K R + L +T+ + ++ L + LKE+ T
Sbjct: 1424 GEVEDL---MVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSLST 1480
Query: 1857 EERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQ 1916
E + A E +Q + ++R+ ++ ++E+ +L + AE + HELE + +E
Sbjct: 1481 ELFKLKNAYE-EALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELE-- 1537
Query: 1917 SLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELEDRVDGVK 1969
+AD++LA + + +AA+E E L ++ S++D ++ ++ + ++
Sbjct: 1538 --KADIQLALE---EAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIE 1585
Score = 196 bits (497), Expect = 3e-49
Identities = 174/695 (25%), Positives = 330/695 (47%), Gaps = 52/695 (7%)
Query: 1247 IEVQLSEEQIRNKDEEIQQLRSKL----EKAEKERNELRLNSDRLESRISELTSELTDER 1302
+E QLSE R K+EEIQ+ S+L + + E EL + ES +S+L+
Sbjct: 1253 LEDQLSEA--RGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRSKQAFT 1310
Query: 1303 NTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRA-AEINGE 1361
E + L+ E + ++ + D L++Q E E + +A L RA ++ N E
Sbjct: 1311 QQTEELKRQLEEENKAKNALAHALQSSRHDCDLLREQYE--EEQEGKAELQRALSKANSE 1368
Query: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEES 1421
V +WR KYE + + E ++ K++L +RL D + E
Sbjct: 1369 V------AQWRTKYETDAIQ--------------RTEELEEAKKKLAQRLQDSEEQVEAV 1408
Query: 1422 QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQR 1481
L+K QRL E++D + +E L+KKQR FD L++ + + + +
Sbjct: 1409 NAKCASLEKTKQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAEL 1468
Query: 1482 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVK 1541
E +E L E F LK EE + ++ +LE E+ D++ Q +++ ++ +++
Sbjct: 1469 EASLKESRSLSTELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELE 1528
Query: 1542 KQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEAR 1601
K + +E + D + L+E ++ E LR+++E+ +++ +++ +DEE+E+ +
Sbjct: 1529 KSRKQIELEKADIQLALEEAEAALEHEEAKILRIQLELTQVKSEIDRKIAEKDEEIEQLK 1588
Query: 1602 QSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRT 1661
++ Q+ ++ M+ L+ E + + +R K+++EG L + Q++ + ++ + L K L+
Sbjct: 1589 RNYQRTVETMQSALDAEVRSRNEAIRLKKKMEGDLNEIEIQLSHANRQAAETL-KHLRSV 1647
Query: 1662 KALLADAQLMLDH-LKNSAPSKREIA-------QLKNQLEESEFTCAAAVKARKAMEVEI 1713
+ L D QL LD L+ K ++A L+ ++EE T +ARK E E+
Sbjct: 1648 QGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEELRATLEQTERARKLAEQEL 1707
Query: 1714 EDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQA---S 1770
D + ++ + T+L +L+ + ++Q+ +E+ D +K K A+ A +
Sbjct: 1708 LDSNERVQLLHTQNTSLIHTKKKLETDLMQLQSEVEDASRDARNAEEKAKKAITDAAMMA 1767
Query: 1771 RDLAQINDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMV--DKSLVSRQEAKIRELE 1828
+L + D A LE + K+ L++ ++ LQ +++ EQ + K + + E +IRELE
Sbjct: 1768 EELKKEQDTSAHLE---RMKKNLEQTVKDLQHRLDEAEQLALKGGKKQIQKLETRIRELE 1824
Query: 1829 TRLEFERTQ----VKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTK 1884
LE E+ + VK L R+KE + E+R + ++ + +++ R
Sbjct: 1825 FELEGEQKKNTESVKGLRKYERRVKELTYQSEEDRKNVLRLQDLVDKLQVKVKSYKRQA- 1883
Query: 1885 EEMGELARKEAEASRK-KHELEMDLESLEAANQSL 1918
EE E A RK +HELE E + A +
Sbjct: 1884 EEADEQANAHLTKFRKAQHELEEAEERADIAESQV 1918
Score = 165 bits (418), Expect = 4e-40
Identities = 194/811 (23%), Positives = 364/811 (44%), Gaps = 102/811 (12%)
Query: 1246 LIEVQLSEEQIR--NK-----DEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSEL 1298
L ++Q E+++ NK +++++ L S LE+ +K R +L N +LE + +
Sbjct: 1008 LDDLQAEEDKVNSLNKTKSKLEQQVEDLESSLEQEKKLRVDLERNKRKLEGDLKLAQESI 1067
Query: 1299 TDERNTGESASQLLDAETAERLRAEKEMKELQT-------QYDALKKQMEVMEMEVMEAR 1351
D N + + L + E + + ++++ QT + L+ ++E +E E+ R
Sbjct: 1068 LDLENDKQQLDERLKKKDFEYCQLQSKVEDEQTLGLQFQKKIKELQARIEELEEEIEAER 1127
Query: 1352 LIRA------AEINGEVDD-----DDAGGEWRLKYE-RAVREVDFTKKRLQQEFEDKLEV 1399
RA ++ E+++ ++AGG + E RE +F K L+++ E+
Sbjct: 1128 ATRAKTEKQRSDYARELEELSERLEEAGGVTSTQIELNKKREAEFLK--LRRDLEEATLQ 1185
Query: 1400 EQQNKRQLERRLGDLQADSEES----QRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE 1455
+ L ++ D A+ E QR Q+L+K+ E+ D +E
Sbjct: 1186 HEAMVAALRKKHADSVAELGEQIDNLQRVKQKLEKEKSEFKLEIDDLSSSMESVSKSKAN 1245
Query: 1456 LEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIA----- 1510
LEK R + +LS+A + + + +L +K L EA L +QLEEK+ ++
Sbjct: 1246 LEKICRTLEDQLSEARGKNEEIQRSLSELTTQKSRLQTEAGELSRQLEEKESIVSQLSRS 1305
Query: 1511 --GFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQML 1568
FTQ+ L+ +L++ E+K + +LA + R +++Q EE EQ G + L
Sbjct: 1306 KQAFTQQTEELKRQLEE----ENKAKNALAHALQSSRHDCDLLREQYEE--EQEGKAE-L 1358
Query: 1569 EQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLRE 1628
++A + E+ + R + + R EE+EEA++ ++L+ E Q+E + +
Sbjct: 1359 QRALSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDSEEQVEAVNAKCASLEKT 1418
Query: 1629 KRELEGKLATLSDQVNRRDF------ESEKRLRKDLKRTKALLADAQLMLD-HLKNSAPS 1681
K+ L+G++ L V R + + ++ K L K ++Q L+ LK S
Sbjct: 1419 KQRLQGEVEDLMVDVERANSLAAALDKKQRNFDKVLAEWKTKCEESQAELEASLKESRSL 1478
Query: 1682 KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREK 1741
E+ +LKN EE+ + K +E EI DL QI + K LE+ +++ EK
Sbjct: 1479 STELFKLKNAYEEALDQLETVKRENKNLEQEIADLTEQIAENGKTIHELEKSRKQIELEK 1538
Query: 1742 NEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQ 1801
+IQ LEE A+A+ + + L+ QLE + K E+ K+
Sbjct: 1539 ADIQLALEE----------------AEAALEHEEAKILRIQLE-LTQVKSEIDRKIAEKD 1581
Query: 1802 SQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQ 1861
++E L+++ +++ + Q A E+ +R E A RLK+ ME E +
Sbjct: 1582 EEIEQLKRNY-QRTVETMQSALDAEVRSRNE------------AIRLKKKMEGDLNEIEI 1628
Query: 1862 RIAAENREKEQN----KRLQRQLRDTKEEMGELARKE-------AEASRKKHELEMDLES 1910
+++ NR+ + + +Q QL+DT+ + + R + A R+ + L+ ++E
Sbjct: 1629 QLSHANRQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQAEVEE 1688
Query: 1911 LEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVD-----SELEDRV 1965
L A + + KLA + + D + ++ +N LI+++ + D SE+ED
Sbjct: 1689 LRATLEQTERARKLAEQELLDSNERV--QLLHTQNTSLIHTKKKLETDLMQLQSEVEDAS 1746
Query: 1966 DGVKSWLSK-NKGPSKAASDDGSLKSSSPTS 1995
++ K K + AA LK TS
Sbjct: 1747 RDARNAEEKAKKAITDAAMMAEELKKEQDTS 1777
Score = 84.7 bits (208), Expect = 8e-16
Identities = 79/327 (24%), Positives = 155/327 (47%), Gaps = 29/327 (8%)
Query: 1247 IEVQLSEEQIRNKDEEIQQLRS----------KLEKAEKERNELRLNSDRLESRISELTS 1296
IE+QLS R E ++ LRS L+ A + + +L+ +E R + L +
Sbjct: 1626 IEIQLSHAN-RQAAETLKHLRSVQGQLKDTQLHLDDALRGQEDLKEQLAIVERRANLLQA 1684
Query: 1297 ELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAA 1356
E+ + R T E + E L + + ++ L TQ +L + +E ++M+
Sbjct: 1685 EVEELRATLEQTERARKLAEQELLDSNERVQLLHTQNTSLIHTKKKLETDLMQ------- 1737
Query: 1357 EINGEVDD---DDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGD 1413
+ EV+D D E + K +A+ + + L++E + +E+ K+ LE+ + D
Sbjct: 1738 -LQSEVEDASRDARNAEEKAK--KAITDAAMMAEELKKEQDTSAHLERM-KKNLEQTVKD 1793
Query: 1414 LQADSEESQR-ALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE 1472
LQ +E+++ AL+ KK+ Q+L +++ + LEG+Q +N E K R+++ + +
Sbjct: 1794 LQHRLDEAEQLALKGGKKQIQKLETRIRELEFELEGEQKKNTESVKGLRKYERRVKELTY 1853
Query: 1473 EAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESK 1532
+++ ++ +LQ D L + S K+Q EE D K + EL++ +
Sbjct: 1854 QSEEDRKNVLRLQDLVDKLQVKVKSYKRQAEEADEQANAHLTKFRKAQHELEEAEERADI 1913
Query: 1533 DEASLAKVKKQLRDLEAK---VKDQEE 1556
E+ + K++ + RD + V + EE
Sbjct: 1914 AESQVNKLRAKTRDFTSSRMVVHESEE 1940
>gi|110611903 myosin, heavy polypeptide 4, skeletal muscle [Homo
sapiens]
Length = 1939
Score = 501 bits (1290), Expect = e-141
Identities = 420/1673 (25%), Positives = 789/1673 (47%), Gaps = 192/1673 (11%)
Query: 376 GKVRVKLDHDGAILDVDEDDVEKANAPSCDRLEDLASLVYLNESSVLHTLRQRYGASLLH 435
GKV K + GA + V ED V N P D++ED+A + +L+E +VL+ L++RY A +++
Sbjct: 58 GKVTAKTEA-GATVTVKEDQVFSMNPPKYDKIEDMAMMTHLHEPAVLYNLKERYAAWMIY 116
Query: 436 TYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSII 495
TY+G + + P VY+ +V+ ++G +R++ PHI++++ AY+ ML R++QSI+
Sbjct: 117 TYSGLFCVTVNPYKWLPVYNPEVVTAYRGKKRQEAPPHIFSISDNAYQFMLTDRENQSIL 176
Query: 496 LLGSSGSGKTTSCQHLVQYLATIAGISGNKVFS-----------VEKWQALYTLLEAFGN 544
+ G SG+GKT + + ++QY ATIA ++G K ++ + LLEAFGN
Sbjct: 177 ITGESGAGKTVNTKRVIQYFATIA-VTGEKKKEEPASGKMQGTLEDQIISANPLLEAFGN 235
Query: 545 SPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFNVFYYLLAC 604
+ T+ N N++RF + + + F G++ASA I+T LLEK RV + +E ++++FY +L+
Sbjct: 236 AKTVRNDNSSRFGKFIRIHFGATGKLASADIETYLLEKSRVTFQLKAERSYHIFYQILS- 294
Query: 605 GDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQA---AMKVLGISPDEQKA 661
+ EL L N + +++ E + +L A A+ +LG + DE+ A
Sbjct: 295 ---NKKPELIEMLLITTNPYDFAFVSQGEITVPSIDDQEELMATDSAVDILGFTADEKVA 351
Query: 662 CWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAIFKHQHKGG 721
+ + A+ H G ++ E + E A KAAYL + +L ++ + K G
Sbjct: 352 IYKLTGAVMHYGNMKFKQKQREEQAEPDGT-EVADKAAYLTSLNSADLLKSLCYPRVKVG 410
Query: 722 TLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLVNRALKSSQHS 781
+ +G + + G +A +Y ++F +V+ +N+ L + Q
Sbjct: 411 ----NEFVTKGQTVQQVYNAVG----------ALAKAIYEKMFLWMVTRINQQLDTKQPR 456
Query: 782 LCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHERTFVQELERYKEENIE 841
+ ++D GF+ + S E+LC N+T ++LQ+ F+ FV E E YK+E IE
Sbjct: 457 QYFIGVLDIAGFEIFDFN------SLEQLCINFTNEKLQQFFNHHMFVLEQEEYKKEGIE 510
Query: 842 LAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEEALVPGASEDTLLERL 901
F D +D A+ L+ ++ G+ +LEEE + P A++ + +L
Sbjct: 511 WEFIDF---------GMDLAACIELI------EKPMGIFSILEEECMFPKATDTSFKNKL 555
Query: 902 FSYYGPQEGDKKGQSPLLHSSKPH-HFLLGHSHGTNWVEYNVTGWLNYTKQNPATQNAPR 960
+ + + + Q P KP HF L H GT V+YN+ GWL+ K +P +
Sbjct: 556 YEQHLGKSNN--FQKPKPAKGKPEAHFSLVHYAGT--VDYNIAGWLDKNK-DPLNETVVG 610
Query: 961 LLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMRKTFTTGMAAVKKKS 1020
L Q S K ++ LF +G+ T + G +GG + +F T A ++
Sbjct: 611 LYQKSAMKTLAFLF---SGAQTAEAEGGGGKKGGKKKG--------SSFQTVSALFRE-- 657
Query: 1021 LCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRVSSSSELDLPSGDHC 1080
++ L+ ++ + HFV C +P +E P
Sbjct: 658 -------NLNKLMTNLRSTHPHFVRCIIP--------------------NETKTPGA--- 687
Query: 1081 EAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNY 1140
++ L+ QLR + +L+ +R+ R+G+P +++++F++R+ VL +
Sbjct: 688 ------MEHELVLHQLRCNGVLEGIRICRKGFPSRILYADFKQRYKVLNASAIPEGQ--- 738
Query: 1141 IVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACR 1200
+D ++A E+LL ++++ + G ++VFF+AG L LEE RDE+ ++ +T QA CR
Sbjct: 739 -FIDSKKASEKLLGSIEIDHTQYKFGHTKVFFKAGLLGTLEEMRDEKLAQLITRTQAICR 797
Query: 1201 GYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKD 1260
G+L R F+K + +I C+Q NI+ VK WPW KL+ ++PL++ +E+++ N
Sbjct: 798 GFLMRVEFRKMMERRESIFCIQYNIRAFMNVKHWPWMKLYFKIKPLLKSAETEKEMANMK 857
Query: 1261 EEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAETAERL 1320
EE ++ + +L K E +R EL L ++L ++ E + A + D ++
Sbjct: 858 EEFEKTKEELAKTEAKRKELEEKMVTLMQEKNDLQLQVQAEADALADAEERCDQLIKTKI 917
Query: 1321 RAEKEMKELQTQYDALKKQMEVMEMEVMEARL-IRAAEINGEVDDDDAGGEWRLKYERAV 1379
+ E ++KE+ + A ++ E+ + +L +E+ ++DD + K E+
Sbjct: 918 QLEAKIKEVTER--AEDEEEINAELTAKKRKLEDECSELKKDIDDLEL---TLAKVEKEK 972
Query: 1380 REVDFTKKRLQQE---FEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLT 1436
+ K L +E ++ + + K+ L+ D + + + L K +L
Sbjct: 973 HATENKVKNLTEEMAGLDETIAKLTKEKKALQEAHQQTLDDLQMEEDKVNTLTKAKTKLE 1032
Query: 1437 AELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAF 1496
++ D + LE ++ +LE+ +R+ + +L A E + +++L + E
Sbjct: 1033 QQVDDLEGSLEQEKKLCMDLERAKRKLEGDLKLAQESTMDTENDKQQLNEKLKKKEFEMS 1092
Query: 1497 SLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEE 1556
+L+ ++E++ +K+ L+A ++++ + + AS AK +KQ DL ++++ E
Sbjct: 1093 NLQGKIEDEQALAIQLQKKIKELQARIEELEEEIEAERASRAKAEKQRSDLSRELEEISE 1152
Query: 1557 ELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLE 1616
L+E G + + E E ++MR+ + + R+ + ++ Q++
Sbjct: 1153 RLEEAGGATSAQIEMNKKREAEFQKMRRDLEESTLQHEATAAALRKKHADSVAELGEQID 1212
Query: 1617 EEYEDKQKVLREKRELEGKLATLSDQVN-----RRDFESEKRLRKD-LKRTKALLADAQL 1670
KQK+ +EK EL+ ++ L+ + + +FE R +D L K + Q
Sbjct: 1213 SLQRVKQKLEKEKSELKMEINDLASNMETVSKAKANFEKMCRTLEDQLSEIKTKEEEQQR 1272
Query: 1671 MLDHLK-NSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTA 1729
+++ L A E + QL+E + + + ++A +IE+L Q+++ KAK+
Sbjct: 1273 LINELSAQKARLHTESGEFSRQLDEKDAMVSQLSRGKQAFTQQIEELKRQLEEETKAKST 1332
Query: 1730 LEEQLSRLQREKNEIQNRLEEDQEDMNEL---MKKHKAAVAQ------------------ 1768
L L + + + ++ + EE+QE EL M K + VAQ
Sbjct: 1333 LAHALQSARHDCDLLREQYEEEQEAKAELQRGMSKANSEVAQWRTKYETDAIQRTEELEE 1392
Query: 1769 ASRDLAQ-INDLQAQLEEANKEKQELQEKLQALQSQVEFL----------------EQSM 1811
A + LAQ + D + +E N + L++ Q LQ++VE L +Q
Sbjct: 1393 AKKKLAQRLQDAEEHVEAVNSKCASLEKTKQRLQNEVEDLMIDVERSNAACIALDKKQRN 1452
Query: 1812 VDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKE 1871
DK L E K + ET+ E E +Q K SL++ L + E D K
Sbjct: 1453 FDKVLA---EWKQKYEETQAELEASQ-KESRSLSTELFKVKNAYEESLDHL----ETLKR 1504
Query: 1872 QNKRLQRQLRDTKEEMG-------ELARKEAEASRKKHELEMDLESLEAANQSLQADLKL 1924
+NK LQ+++ D E++ EL + + + +K EL+ LE EA+ + + +
Sbjct: 1505 ENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKSELQTSLEEAEASLEHEEGKILR 1564
Query: 1925 AFKRIGDLQAAIEDEM-ESDENEDLIN-------SEGDSDVDSELEDRVDGVK 1969
+ +++ I+ ++ E DE D + S +D+E+ R D ++
Sbjct: 1565 IQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQSTLDAEIRSRNDALR 1617
Score = 192 bits (487), Expect = 4e-48
Identities = 153/687 (22%), Positives = 333/687 (48%), Gaps = 47/687 (6%)
Query: 1253 EEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLL 1312
E+ R ++++ ++++K E+ ++ NEL RL + E + +L DE++ SQL
Sbjct: 1250 EKMCRTLEDQLSEIKTKEEEQQRLINELSAQKARLHTESGEFSRQL-DEKDA--MVSQLS 1306
Query: 1313 DAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWR 1372
+ A + E+ ++L+ + A ++ + L+R ++ +A E +
Sbjct: 1307 RGKQAFTQQIEELKRQLEEETKAKSTLAHALQSARHDCDLLREQY----EEEQEAKAELQ 1362
Query: 1373 LKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKC 1432
+A EV + + + + + E ++ K++L +RL D + E L+K
Sbjct: 1363 RGMSKANSEVAQWRTKYETDAIQRTEELEEAKKKLAQRLQDAEEHVEAVNSKCASLEKTK 1422
Query: 1433 QRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLL 1492
QRL E++D + +E L+KKQR FD L++ ++ + + + E Q+E L
Sbjct: 1423 QRLQNEVEDLMIDVERSNAACIALDKKQRNFDKVLAEWKQKYEETQAELEASQKESRSLS 1482
Query: 1493 AEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVK 1552
E F +K EE + ++ +L+ E+ D++ Q ++ + +++K + L+ +
Sbjct: 1483 TELFKVKNAYEESLDHLETLKRENKNLQQEISDLTEQIAEGGKHIHELEKVKKQLDHEKS 1542
Query: 1553 DQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQME 1612
+ + L+E +++ E LR+++E+ +++ +++ +DEE+++ +++ + ++ M+
Sbjct: 1543 ELQTSLEEAEASLEHEEGKILRIQLELNQVKSEIDRKIAEKDEELDQLKRNHLRVVESMQ 1602
Query: 1613 VQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQLML 1672
L+ E + LR K+++EG L + Q+N + ++ + LR +L+ T+ +L D QL L
Sbjct: 1603 STLDAEIRSRNDALRIKKKMEGDLNEMEIQLNHANRQAAEALR-NLRNTQGILKDTQLHL 1661
Query: 1673 DH-LKNSAPSKREIAQLKN-------QLEESEFTCAAAVKARKAMEVEIED-------LH 1717
D ++ K ++A ++ ++EE + + RK E E+ D LH
Sbjct: 1662 DDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLH 1721
Query: 1718 LQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQED----------MNELMKKHK---A 1764
Q + K LE +S++Q E +I +E M E +KK + A
Sbjct: 1722 TQNTSLINTKKKLETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSA 1781
Query: 1765 AVAQASRDLAQ-INDLQAQLEEA--------NKEKQELQEKLQALQSQVEFLEQSMVDK- 1814
+ + +++ Q + DLQ +L+EA K+ Q+L+ +++ L+S+VE ++ V+
Sbjct: 1782 HLERMKKNMEQTVKDLQLRLDEAEQLALKGGKKQIQKLEARVRELESEVESEQKHNVEAV 1841
Query: 1815 SLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNK 1874
+ + E +++EL + E +R + RL+ L +L+ ++ + ++ N + +
Sbjct: 1842 KGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLAKFR 1901
Query: 1875 RLQRQLRDTKEEMGELARKEAEASRKK 1901
+LQ +L + KE ++A + R K
Sbjct: 1902 KLQHELEEAKER-ADIAESQVNKLRVK 1927
Score = 74.7 bits (182), Expect = 9e-13
Identities = 64/302 (21%), Positives = 146/302 (48%), Gaps = 11/302 (3%)
Query: 1256 IRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESASQLLDAE 1315
+RN ++ + L+ A + +++L+ +E R + + +E+ + R + E +
Sbjct: 1647 LRNTQGILKDTQLHLDDAIRGQDDLKEQLAMVERRANLMQAEVEELRASLERTERGRKMA 1706
Query: 1316 TAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDD-DAGGEWRLK 1374
E L A + ++ L TQ +L + +E ++ ++I GE++D K
Sbjct: 1707 EQELLDASERVQLLHTQNTSLINTKKKLETDI--------SQIQGEMEDIVQEARNAEEK 1758
Query: 1375 YERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQR-ALQQLKKKCQ 1433
++A+ + + L++E + +E+ K+ +E+ + DLQ +E+++ AL+ KK+ Q
Sbjct: 1759 AKKAITDAAMMAEELKKEQDTSAHLERM-KKNMEQTVKDLQLRLDEAEQLALKGGKKQIQ 1817
Query: 1434 RLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA 1493
+L A +++ + +E +Q N E K R+ + + + + + ++ +LQ D L
Sbjct: 1818 KLEARVRELESEVESEQKHNVEAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQT 1877
Query: 1494 EAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKD 1553
+ + K+Q EE + K L+ EL++ + E+ + K++ + R++ KV
Sbjct: 1878 KVKAYKRQAEEAEEQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSREVHTKVIS 1937
Query: 1554 QE 1555
+E
Sbjct: 1938 EE 1939
Score = 55.1 bits (131), Expect = 7e-07
Identities = 67/267 (25%), Positives = 124/267 (46%), Gaps = 44/267 (16%)
Query: 1248 EVQLSEEQIRNKDEEIQQLRSKLEKAEKERN----ELRLNSDR----------------- 1286
++ + E + E+++LR+ LE+ E+ R EL S+R
Sbjct: 1674 QLAMVERRANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKK 1733
Query: 1287 LESRISELTSELTD----ERNTGESASQLLD--AETAERLRAEKEMKELQTQYDALKKQM 1340
LE+ IS++ E+ D RN E A + + A AE L+ E ++ + +KK M
Sbjct: 1734 LETDISQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKE---QDTSAHLERMKKNM 1790
Query: 1341 EVMEMEVMEARLIRAAEINGEVDDDDAGGEWRL-KYERAVREVDFTKKRLQQEFEDKLEV 1399
E ++ ++ RL A ++ + GG+ ++ K E VRE++ + E E K V
Sbjct: 1791 E-QTVKDLQLRLDEAEQLALK------GGKKQIQKLEARVRELE-----SEVESEQKHNV 1838
Query: 1400 EQ-QNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEK 1458
E + R+ ERR+ +L +EE ++ + +L+ +L +++ K E + +++
Sbjct: 1839 EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAEEQSNVNLA 1898
Query: 1459 KQRRFDSELSQAHEEAQREKLQREKLQ 1485
K R+ EL +A E A + Q KL+
Sbjct: 1899 KFRKLQHELEEAKERADIAESQVNKLR 1925
Score = 32.7 bits (73), Expect = 3.7
Identities = 57/280 (20%), Positives = 118/280 (42%), Gaps = 43/280 (15%)
Query: 1082 AGLLQLDVPLLRTQL----RGSR-----LLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHL 1132
A L+Q +V LR L RG + LLDA + + + +++ + +
Sbjct: 1682 ANLMQAEVEELRASLERTERGRKMAEQELLDASERVQLLHTQNTSLINTKKKLET---DI 1738
Query: 1133 TKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNL 1192
++ G +V E R EE + + + L + + L R+++ EQT ++L
Sbjct: 1739 SQIQGEMEDIVQEARNAEEKAKKAITDAAMMAEELKKEQDTSAHLERMKKNM-EQTVKDL 1797
Query: 1193 TLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLS 1252
L + + + LA++ +K I+K L VR L E ++
Sbjct: 1798 QL--------------RLDEAEQLALKGGKKQIQK-----------LEARVREL-ESEVE 1831
Query: 1253 EEQIRNKDEEIQQLRS---KLEKAEKERNELRLNSDRLESRISELTSELTDERNTGESAS 1309
EQ N E ++ LR ++++ + E R N RL+ + +L +++ + E A
Sbjct: 1832 SEQKHNV-EAVKGLRKHERRVKELTYQTEEDRKNILRLQDLVDKLQTKVKAYKRQAEEAE 1890
Query: 1310 QLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVME 1349
+ + A+ + + E++E + + D + Q+ + ++ E
Sbjct: 1891 EQSNVNLAKFRKLQHELEEAKERADIAESQVNKLRVKSRE 1930
>gi|150010558 myosin, heavy polypeptide 15 [Homo sapiens]
Length = 1946
Score = 494 bits (1272), Expect = e-139
Identities = 421/1641 (25%), Positives = 756/1641 (46%), Gaps = 190/1641 (11%)
Query: 350 EKVWLVHRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKANAPSCDRLED 409
+K W+ + + +++K E +G V V+ DG L + ED +++ N P + +ED
Sbjct: 52 KKCWIPDGENAYIEAEVKGSE---DDGTVIVETA-DGESLSIKEDKIQQMNPPEFEMIED 107
Query: 410 LASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRRED 469
+A L +LNE+SVLHTL++RYG +++TY+G + + P VY ++VM +KG RR +
Sbjct: 108 MAMLTHLNEASVLHTLKRRYGQWMIYTYSGLFCVTINPYKWLPVYQKEVMAAYKGKRRSE 167
Query: 470 MAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGI--SGNKVF 527
PHI+AVA A++ ML +R++QSI+ G SG+GKT + +H++QY ATIA + S K
Sbjct: 168 APPHIFAVANNAFQDMLHNRENQSILFTGESGAGKTVNSKHIIQYFATIAAMIESRKKQG 227
Query: 528 SVE-KWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVA 586
++E + T+LEAFGN+ T+ N N++RF + + + F G ++S I LLEK RV
Sbjct: 228 ALEDQIMQANTILEAFGNAKTLRNDNSSRFGKFIRMHFGARGMLSSVDIDIYLLEKSRVI 287
Query: 587 RRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNV--FGIVPL-AKPEEKQKAAQQFS 643
+ A E +++FY +L+ + ELH L N F A E A++
Sbjct: 288 FQQAGERNYHIFYQILSG-----QKELHDLLLVSANPSDFHFCSCGAVTVESLDDAEELL 342
Query: 644 KLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKAAYLLG 703
+ AM +LG PDE+ C+ + AI H G ++ E + + E A KAA+L+G
Sbjct: 343 ATEQAMDILGFLPDEKYGCYKLTGAIMHFGNMKFKQKPREE-QLEADGTENADKAAFLMG 401
Query: 704 CSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEG-MAAGLYSE 762
+ EL + + K G + G + + C G ++ +Y
Sbjct: 402 INSSELVKCLIHPRIKVGNEYVTR---------------GQTIEQVTCAVGALSKSMYER 446
Query: 763 LFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRL 822
+F LV+ +NRAL + + I+D GF+ E S E+LC N+T ++LQ+
Sbjct: 447 MFKWLVARINRALDAKLSRQFFIGILDITGFEILEYN------SLEQLCINFTNEKLQQF 500
Query: 823 FHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWL 882
F+ FV E E YK+E+IE V L + ++ G+L +
Sbjct: 501 FNWHMFVLEQEEYKKESIEW---------------VSIGFGLDLQACIDLIEKPMGILSI 545
Query: 883 LEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPH------HFLLGHSHGTN 936
LEEE + P A++ T +LF + G+S L KP HF L H G
Sbjct: 546 LEEECMFPKATDLTFKTKLFDNHF-------GKSVHLQKPKPDKKKFEAHFELVHYAGV- 597
Query: 937 WVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQ 996
V YN++GWL K + + + Q S +++++LF + + + + G+
Sbjct: 598 -VPYNISGWLEKNK-DLLNETVVAVFQKSSNRLLASLFENYMSTDSAIPFGEKKRKKGA- 654
Query: 997 LALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAG 1056
+F T +A++ K++L + L+ +K + HFV C P G
Sbjct: 655 -----------SFQT-VASLHKENL--------NKLMTNLKSTAPHFVRCINPNVNKIPG 694
Query: 1057 EPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHM 1116
LD L+ QLR + +L+ R+ R+G+P+ +
Sbjct: 695 I-----------------------------LDPYLVLQQLRCNGVLEGTRICREGFPNRL 725
Query: 1117 VFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGT 1176
+++F++R+ +L P K V R+A EELL L+++ + G+++VFF+AG
Sbjct: 726 QYADFKQRYCILNPRTFPKSK----FVSSRKAAEELLGSLEIDHTQYRFGITKVFFKAGF 781
Query: 1177 LARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPW 1236
L +LE RDE+ S+ TLFQA +G L R F+K + A+ +Q NI+ VK+WPW
Sbjct: 782 LGQLEAIRDERLSKVFTLFQARAQGKLMRIKFQKILEERDALILIQWNIRAFMAVKNWPW 841
Query: 1237 WKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTS 1296
+LF ++PL++ E++ EE QL+ LEK+E +R EL+ L ++L
Sbjct: 842 MRLFFKIKPLVKSSEVGEEVAGLKEECAQLQKALEKSEFQREELKAKQVSLTQEKNDLIL 901
Query: 1297 ELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAA 1356
+L E+ T + + + +++ E +KEL R+
Sbjct: 902 QLQAEQETLANVEEQCEWLIKSKIQLEARVKEL-------------------SERVEEEE 942
Query: 1357 EINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQA 1416
EIN E+ A G R + + F K+ + E L ++ KR E ++ +L
Sbjct: 943 EINSEL---TARG-------RKLEDECFELKKEIDDLETMLVKSEKEKRTTEHKVKNLTE 992
Query: 1417 DSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQR 1476
+ E + +L + + + Q T L ++ + L K + + ++ + ++
Sbjct: 993 EVEFLNEDISKLNRAAKVVQEAHQQTLDDLHMEEEKLSSLSKANLKLEQQVDELEGALEQ 1052
Query: 1477 EKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS 1536
E+ R +RE L ++ +E + +++ E EL ++S+ ++
Sbjct: 1053 ERKARMNCERELHKLEGNLKLNRESMENLESSQRHLAEELRKKELELSQMNSKVENEKGL 1112
Query: 1537 LAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEE 1596
+A+++K +++L+ ++KD +E+L+ + T +MER R ++++ +E
Sbjct: 1113 VAQLQKTVKELQTQIKDLKEKLEAERTT-----------RAKMERERADLTQDLADLNER 1161
Query: 1597 VEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQVNRRDFESEKRLRK 1656
+EE S L Q+E+ ++E + QK+ R+ E T S + +R +S L
Sbjct: 1162 LEEVGGS---SLAQLEITKKQETK-FQKLHRDMEEATLHFETTSASLKKRHADSLAELEG 1217
Query: 1657 DLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDL 1716
++ + + + K+ + + E+ L ++E+ A A K E + +
Sbjct: 1218 QVENLQQVKQKLE------KDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEA 1271
Query: 1717 HLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQI 1776
++D + + L Q ++L E E RLEE + +N+L + + S QI
Sbjct: 1272 TAKLDKVTQLANDLAAQKTKLWSESGEFLRRLEEKEALINQLSR-------EKSNFTRQI 1324
Query: 1777 NDLQAQLEEANKEKQELQEKLQALQSQVEFL----EQSMVDKSLVSRQEAKIRE--LETR 1830
DL+ QLE+ K + L LQ Q + L E+ K+ + R +K+ ++ R
Sbjct: 1325 EDLRGQLEKETKSQSALAHALQKAQRDCDLLREQYEEEQEVKAELHRTLSKVNAEMVQWR 1384
Query: 1831 LEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENRE---KEQNKRLQRQLRDTKEEM 1887
+++E ++R E L KE +L E + A R + +LQ +L D ++
Sbjct: 1385 MKYENNVIQRTEDLEDAKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDL 1444
Query: 1888 GELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENED 1947
G++ A +K+ + L + ++ QA L + K + L + ++++ E
Sbjct: 1445 GKVRSAAARLDQKQLQSGKALADWKQKHEESQALLDASQKEVQALSTELL-KLKNTYEES 1503
Query: 1948 LINSEGDSDVDSELEDRVDGV 1968
++ E + L++ + +
Sbjct: 1504 IVGQETLRRENKNLQEEISNL 1524
Score = 154 bits (389), Expect = 8e-37
Identities = 174/803 (21%), Positives = 363/803 (45%), Gaps = 79/803 (9%)
Query: 1176 TLARLEEQRDEQTS---RNLTLFQAACRGYLARQHFKKRKIQDLA--------IRCVQKN 1224
+LA+LE + ++T + + +A KKR LA ++ V++
Sbjct: 1169 SLAQLEITKKQETKFQKLHRDMEEATLHFETTSASLKKRHADSLAELEGQVENLQQVKQK 1228
Query: 1225 IKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIRNKDEE-IQQLRSKLEKAEKERNELRLN 1283
++K+K L T V + + + E++ EE + + +KL+K + N+L
Sbjct: 1229 LEKDKSDLQLEVDDLLTRVEQMTRAKANAEKLCTLYEERLHEATAKLDKVTQLANDLAAQ 1288
Query: 1284 SDRL--------------ESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKEL 1329
+L E+ I++L+ E ++ E L+ ET + +++
Sbjct: 1289 KTKLWSESGEFLRRLEEKEALINQLSREKSNFTRQIEDLRGQLEKETKSQSALAHALQKA 1348
Query: 1330 QTQYDALKKQMEVMEMEVMEARLIRA-AEINGEVDDDDAGGEWRLKYERAV----REVDF 1384
Q D L++Q E E + ++A L R +++N E+ +WR+KYE V +++
Sbjct: 1349 QRDCDLLREQYE--EEQEVKAELHRTLSKVNAEMV------QWRMKYENNVIQRTEDLED 1400
Query: 1385 TKKRLQ---QEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQD 1441
KK L QE + + V LER LQ + ++ L +++ RL D
Sbjct: 1401 AKKELAIRLQEAAEAMGVANARNASLERARHQLQLELGDALSDLGKVRSAAARL-----D 1455
Query: 1442 TKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQ 1501
K G+ + ++ Q HEE+Q + Q+E L E LK
Sbjct: 1456 QKQLQSGKAL-------------ADWKQKHEESQA---LLDASQKEVQALSTELLKLKNT 1499
Query: 1502 LEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQ 1561
EE + ++ +L+ E+ ++++Q + +L +++K + +E + + + L+E
Sbjct: 1500 YEESIVGQETLRRENKNLQEEISNLTNQVREGTKNLTEMEKVKKLIEEEKTEVQVTLEET 1559
Query: 1562 AGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYED 1621
G ++ E L ++E+ + +++ +DEE+E R+ Q + ++ L+ E +
Sbjct: 1560 EGALERNESKILHFQLELLEAKAELERKLSEKDEEIENFRRKQQCTIDSLQSSLDSEAKS 1619
Query: 1622 KQKVLREKRELEGKLATLSDQV---NRRDFESEK---RLRKDLKRTKALLADA-QLMLDH 1674
+ +V R K+++E L + Q+ NR+ E+ K +L+ +K + L D+ QL D
Sbjct: 1620 RIEVTRLKKKMEEDLNEMELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDL 1679
Query: 1675 LKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQL 1734
+ A ++R + L+++LE+ + R+ E E+ + +I+ T+L Q
Sbjct: 1680 KEQVAVAERRNSLLQSELEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQK 1739
Query: 1735 SRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQ 1794
+L+ + +Q EE ++ +K K A +A+ ++ Q + + ++ ++
Sbjct: 1740 KKLEADVARMQKEAEEVVQECQNAEEKAKKAAIEAANLSEELKKKQDTIAHLERTRENME 1799
Query: 1795 EKLQALQSQVEFLEQS--MVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENM 1852
+ + LQ ++ EQ M + + + E+++RELE LE E + + A RL+ +
Sbjct: 1800 QTITDLQKRLAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCI 1859
Query: 1853 EKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEA-----EASRKKHELEMD 1907
++LT + ++ +R + Q +LQ ++++ K+++ E+A +A + +++HEL
Sbjct: 1860 KELTYQAEEDKKNLSRMQTQMDKLQLKVQNYKQQV-EVAETQANQYLSKYKKQQHELNEV 1918
Query: 1908 LESLEAANQSLQADLKLAFKRIG 1930
E E A + LK+ + G
Sbjct: 1919 KERAEVAESQVN-KLKIKAREFG 1940
Score = 85.9 bits (211), Expect = 4e-16
Identities = 78/318 (24%), Positives = 156/318 (49%), Gaps = 18/318 (5%)
Query: 1247 IEVQLS--EEQIRNKDEEIQQLRSKLEKAEKERNE-LRLNSDRLES------RISELTSE 1297
+E+QLS Q+ + + QL+ +++ + + ++ +LNSD E R S L SE
Sbjct: 1637 MELQLSCANRQVSEATKSLGQLQIQIKDLQMQLDDSTQLNSDLKEQVAVAERRNSLLQSE 1696
Query: 1298 LTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVMEARLIRAAE 1357
L D R+ E + E L A + + TQ +L Q + +E +V AR+ + AE
Sbjct: 1697 LEDLRSLQEQTERGRRLSEEELLEATERINLFYTQNTSLLSQKKKLEADV--ARMQKEAE 1754
Query: 1358 INGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQAD 1417
EV + E + K +A E + L+++ +D + ++ + +E+ + DLQ
Sbjct: 1755 ---EVVQECQNAEEKAK--KAAIEAANLSEELKKK-QDTIAHLERTRENMEQTITDLQKR 1808
Query: 1418 -SEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQR 1476
+E Q AL +K+ Q+L + +++ + LEG+ R+ E ++ RR + + + +A+
Sbjct: 1809 LAEAEQMALMGSRKQIQKLESRVRELEGELEGEIRRSAEAQRGARRLERCIKELTYQAEE 1868
Query: 1477 EKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEAS 1536
+K ++Q + D L + + KQQ+E + + K + EL ++ + E+
Sbjct: 1869 DKKNLSRMQTQMDKLQLKVQNYKQQVEVAETQANQYLSKYKKQQHELNEVKERAEVAESQ 1928
Query: 1537 LAKVKKQLRDLEAKVKDQ 1554
+ K+K + R+ KV+++
Sbjct: 1929 VNKLKIKAREFGKKVQEE 1946
>gi|153945715 myosin VC [Homo sapiens]
Length = 1742
Score = 302 bits (773), Expect = 3e-81
Identities = 344/1470 (23%), Positives = 654/1470 (44%), Gaps = 197/1470 (13%)
Query: 340 IAAEEAWNETEKVWLVHRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILDVDEDDVEKA 399
+A E + + +VW+ + ++++ +++ + + +R+ L+ DG LD +
Sbjct: 1 MAVAELYTQYNRVWIPDPEEVWKSAEI-AKDYRVGDKVLRLLLE-DGTELDYSVNPESLP 58
Query: 400 NAPSCDRL---EDLASLVYLNESSVLHTLRQRYGAS-LLHTYAGPSLLVLGPRGAPAVYS 455
+ D L DL +L YL+E +VLH LR R+ S L++TY+G L+ + P +Y
Sbjct: 59 PLRNPDILVGENDLTALSYLHEPAVLHNLRIRFAESKLIYTYSGIILVAMNPYKQLPIYG 118
Query: 456 EKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYL 515
+ ++H + G DM PHI+AVA+ AY+ M + ++QSII+ G SG+GKT S ++ ++Y
Sbjct: 119 DAIIHAYSGQNMGDMDPHIFAVAEEAYKQMARNNRNQSIIVSGESGAGKTVSARYAMRYF 178
Query: 516 ATIAGISGNKVFSVEKWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASI 575
AT++ SG+ +K A + EA GN+ T N N++RF + + FD+ Q+ A++
Sbjct: 179 ATVSK-SGSNAHVEDKVLASNPITEAVGNAKTTRNDNSSRFGKYTEISFDEQNQIIGANM 237
Query: 576 QTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEK 635
T LLEK RV + +E +++FY L A + L L E N + E
Sbjct: 238 STYLLEKSRVVFQSENERNYHIFYQLCASAQQSEFKHLKLGSAEEFNYTRMGGNTVIEGV 297
Query: 636 QKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWA 695
A+ + Q +LG D Q + ILAAI HLG T E R +
Sbjct: 298 NDRAEMV-ETQKTFTLLGFKEDFQMDVFKILAAILHLGNVQITAVGNE-------RSSVS 349
Query: 696 QKAAYL-LGCSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEG 754
+ ++L + C L L S + S+ E+ + T P+ A+ +
Sbjct: 350 EDDSHLKVFCELLGLESGRVAQWLCNRKIVTSS-------ETVVKPMTRPQ--AVNARDA 400
Query: 755 MAAGLYSELFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNY 814
+A +Y+ LF +V +N+AL+ S + ++D GF+ + SFE+ C NY
Sbjct: 401 LAKKIYAHLFDFIVERINQALQFSGKQHTFIGVLDIYGFETFDVN------SFEQFCINY 454
Query: 815 TQDRLQRLFHERTFVQELERYKEENIE---LAFDDLEPPTDDSVAAVDQASHQSLVRSLA 871
++LQ+ F+ F E E Y +E+I + F D +P D
Sbjct: 455 ANEKLQQQFNMHVFKLEQEEYMKEDIPWTLIDFYDNQPVID------------------- 495
Query: 872 RTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGH 931
+ G+L LL+EE L+P +++ L++L++ + ++PL + +
Sbjct: 496 LIEAKMGILELLDEECLLPHGTDENWLQKLYNNF-------VNRNPLFEKPRMSNTSFVI 548
Query: 932 SHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGL 991
H + VEY G+L ++ +L+ S+ + +N F + GS+ +
Sbjct: 549 QHFADKVEYKCEGFLE-KNRDTVYDMLVEILRASKFHLCANFFQENPTPPSPF-GSMITV 606
Query: 992 EGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVA 1051
+ Q+ + K F T + + + SL + L++T+ + H+V C P
Sbjct: 607 KSAKQVIKPNS----KHFRTTVGSKFRSSLYL--------LMETLNATTPHYVRCIKP-- 652
Query: 1052 EGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQG 1111
++ LP + D + QLR +L+ +R+ Q
Sbjct: 653 ------------------NDEKLP---------FEFDSKRIVQQLRACGVLETIRISAQS 685
Query: 1112 YPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVF 1171
YP + EF R+ +L +TK + D++ + +L L + + G +++F
Sbjct: 686 YPSRWTYIEFYSRYGIL---MTK---QELSFSDKKEVCKVVLHRLIQDSNQYQFGKTKIF 739
Query: 1172 FRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCV---QKNIKK- 1227
FRAG +A LE+ R ++ ++ + Q RG+L R+ F + + L I+ Q+ ++K
Sbjct: 740 FRAGQVAYLEKLRLDKLRQSCVMVQKHMRGWLQRKKFLRERRAALIIQQYFRGQQTVRKA 799
Query: 1228 ---------------NKGVKDWPWWKLFTTVR-PLIEVQ------LSEEQIRNKDEE--- 1262
K + + L+ +R I +Q L+ + R EE
Sbjct: 800 ITAVALKEAWAAIIIQKHCRGYLVRSLYQLIRMATITMQAYSRGFLARRRYRKMLEEHKA 859
Query: 1263 -IQQLRSKLEKAEKERNELR--LNSDRLESRISELTSELTD---------ERNTGESASQ 1310
I Q ++ A + +R + + +L R+ L +L D E+ T +A +
Sbjct: 860 VILQKYARAWLARRRFQSIRRFVLNIQLTYRVQRLQKKLEDQNKENHGLVEKLTSLAALR 919
Query: 1311 LLDAETAERLRAEKEMKEL-QTQYDALKKQMEVMEMEVMEARLIRAAEINGEVDDDDAGG 1369
D E ++L AE E + Y+ K+ + +E +L + + N E++
Sbjct: 920 AGDVEKIQKLEAELEKAATHRRNYEEKGKRYR----DAVEEKLAKLQKHNSELETQKE-- 973
Query: 1370 EWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERRLGDLQADSEESQRALQQLK 1429
+ +LK + E+ L ++ D ++ E++ + LE+ + +++ ++ +Q LK
Sbjct: 974 QIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLLEK---SFELKTQDYEKQIQSLK 1030
Query: 1430 KKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHE-EAQREKLQREKLQREK 1488
++ + L E + +EG+ V + L+ + R ++ E E + E LQ +K+ EK
Sbjct: 1031 EEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEFEKEIELLQAQKIDVEK 1090
Query: 1489 DMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEA-----------SL 1537
+ S K+++ EK +I K + +++D+ S+ S ++ +
Sbjct: 1091 HVQ-----SQKREMREKMSEIT----KQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAY 1141
Query: 1538 AKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEV 1597
+KK R LE+ + Q++ +++ I+ L + L E+ +++ +E + +
Sbjct: 1142 EGLKKATRVLESHFQSQKDCYEKE---IEALNFKVVHLSQEINHLQKLFREENDINESIR 1198
Query: 1598 EEARQSCQKKL-----KQMEVQLEEEYEDKQKVLREKRE-LEGKLATLSDQVNRRDFESE 1651
E + + + KQ +LE++ +D + L E+ E ++GKL LS+Q++R E E
Sbjct: 1199 HEVTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHRSQ-EEE 1257
Query: 1652 KRLRKDLKRTKAL-LADAQLMLDHLKNSAPSKREIAQLKNQLE-ESEFTCAAAVKARKAM 1709
RK L+ + + + ++D ++ + LK Q E ESE C +A + +
Sbjct: 1258 GTQRKALEAQNEIHTKEKEKLIDKIQEMQEAS---DHLKKQFETESEVKCNFRQEASR-L 1313
Query: 1710 EVEIEDLHLQIDDIAKAKTALEEQLSRLQR 1739
+E DL ++D + L++Q+ L +
Sbjct: 1314 TLENRDLEEELDMKDRVIKKLQDQVKTLSK 1343
Score = 91.3 bits (225), Expect = 9e-18
Identities = 113/489 (23%), Positives = 212/489 (43%), Gaps = 74/489 (15%)
Query: 1482 EKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQ----ESKD---- 1533
++LQ++ + E L ++L AG +K+ LEAEL+ ++ E K
Sbjct: 892 QRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYR 951
Query: 1534 ---EASLAKVKKQLRDLEA-------KVKDQEEELDEQAGT--------IQMLEQAKLRL 1575
E LAK++K +LE K++++ EEL E+ +Q E+ ++ L
Sbjct: 952 DAVEEKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDNLTKQLFDDVQKEERQRMLL 1011
Query: 1576 EMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGK 1635
E E Q + K+++S EE+ ++ + + Q++ +E E+ + E L +
Sbjct: 1012 EKSFELKTQDYEKQIQSLKEEI----KALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQ 1067
Query: 1636 LATLSD--------QVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQ 1687
+ T+S+ Q + D E + +K R K QL+ + S+ +
Sbjct: 1068 VKTISEFEKEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRLSVED 1127
Query: 1688 LKNQLEESE--FTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQ 1745
L++ E+ E F KA + +E + Q D K AL ++ L +E N +Q
Sbjct: 1128 LEHLNEDGELWFAYEGLKKATRVLESHFQS---QKDCYEKEIEALNFKVVHLSQEINHLQ 1184
Query: 1746 NRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQEKLQALQSQVE 1805
+L ++ D+NE ++ V + + + I D + Q+ E K+KQ+L+ +L
Sbjct: 1185 -KLFREENDINESIRHE---VTRLTSENMMIPDFKQQISELEKQKQDLEIRLN------- 1233
Query: 1806 FLEQSMVDKSLVSRQEAKIRELETRL----EFERTQVKRLESLASRLKENMEKLTEERDQ 1861
EQ+ + + K+ EL +L E E TQ K LE+ E T+E+++
Sbjct: 1234 --EQA-------EKMKGKLEELSNQLHRSQEEEGTQRKALEA-------QNEIHTKEKEK 1277
Query: 1862 RIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQAD 1921
I +E + L++Q E ++ + + + +LE +L+ + + LQ
Sbjct: 1278 LIDKIQEMQEASDHLKKQFETESEVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQ 1337
Query: 1922 LKLAFKRIG 1930
+K K IG
Sbjct: 1338 VKTLSKTIG 1346
Score = 85.1 bits (209), Expect = 6e-16
Identities = 128/541 (23%), Positives = 239/541 (44%), Gaps = 94/541 (17%)
Query: 1498 LKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQEEE 1557
L+++LE+++ + G +K+ SL A + K EA L K R+ E K K +
Sbjct: 894 LQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEKGKRYRDA 953
Query: 1558 LDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQ-MEVQLE 1616
++E+ AKL Q H+ E+E++ E+++ Q ++LK+ M+ +
Sbjct: 954 VEEKL--------AKL----------QKHNSELETQKEQIQLKLQEKTEELKEKMDNLTK 995
Query: 1617 EEYEDKQKVLREKRELEGKLATLSDQVNRRDFESE-KRLRKDLKRTKALLADAQLMLDHL 1675
+ ++D QK R++ LE S ++ +D+E + + L++++K K D ++ L HL
Sbjct: 996 QLFDDVQKEERQRMLLEK-----SFELKTQDYEKQIQSLKEEIKALK----DEKMQLQHL 1046
Query: 1676 KN-----SAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAK----A 1726
S K E+A+L Q VK E EIE L Q D+ K
Sbjct: 1047 VEGEHVTSDGLKAEVARLSKQ-----------VKTISEFEKEIELLQAQKIDVEKHVQSQ 1095
Query: 1727 KTALEEQLSRLQREKNE------IQNRLE-EDQEDMNELMKKHKA--AVAQASRDLAQIN 1777
K + E++S + ++ E +++RL ED E +NE + A + +A+R L +
Sbjct: 1096 KREMREKMSEITKQLLESYDIEDVRSRLSVEDLEHLNEDGELWFAYEGLKKATRVLE--S 1153
Query: 1778 DLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQ 1837
Q+Q + KE + L K+ L ++ L++ + R+E I E R +
Sbjct: 1154 HFQSQKDCYEKEIEALNFKVVHLSQEINHLQK-------LFREENDINESI------RHE 1200
Query: 1838 VKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEA 1897
V RL S + + ++++E Q+ E R EQ ++++ +L + ++ +E E
Sbjct: 1201 VTRLTSENMMIPDFKQQISELEKQKQDLEIRLNEQAEKMKGKLEELSNQLHR--SQEEEG 1258
Query: 1898 SRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSE----- 1952
+++K +LEA N+ + + +I ++Q A + + E E +
Sbjct: 1259 TQRK--------ALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETESEVKCNFRQEA 1310
Query: 1953 -----GDSDVDSELEDRVDGVKSWLSKNKGPSKAASDDGSLKSSS-PTSYWKSLAPDRSD 2006
+ D++ EL+ + +K + K SK + SSS P Y L R D
Sbjct: 1311 SRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHSSSGPKEYLGMLQYKRED 1370
Query: 2007 D 2007
+
Sbjct: 1371 E 1371
Score = 61.2 bits (147), Expect = 1e-08
Identities = 76/353 (21%), Positives = 161/353 (45%), Gaps = 28/353 (7%)
Query: 1247 IEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTGE 1306
++ Q E+QI++ EEI+ L+ + + + + SD L++ ++ L+ ++ E
Sbjct: 1017 LKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHVTSDGLKAEVARLSKQVKTISEF-E 1075
Query: 1307 SASQLLDAETAE-RLRAEKEMKELQTQYDALKKQM-EVMEMEVMEARLIRAAEINGEVDD 1364
+LL A+ + + + +E++ + + KQ+ E ++E + +RL + E +++
Sbjct: 1076 KEIELLQAQKIDVEKHVQSQKREMREKMSEITKQLLESYDIEDVRSRL--SVEDLEHLNE 1133
Query: 1365 DDAGGEWRLKYERAVREVDFTKKRLQQE---FEDKLEVEQQNKRQLERRLGDLQADSEES 1421
D GE YE + + Q + +E ++E L + + LQ E
Sbjct: 1134 D---GELWFAYEGLKKATRVLESHFQSQKDCYEKEIEALNFKVVHLSQEINHLQKLFREE 1190
Query: 1422 QRALQQLKKKCQRLTAE---LQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQREK 1478
+ ++ + RLT+E + D K QQ+ ELEK+++ + L+ E+A++ K
Sbjct: 1191 NDINESIRHEVTRLTSENMMIPDFK-----QQIS--ELEKQKQDLEIRLN---EQAEKMK 1240
Query: 1479 LQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEASLA 1538
+ E+L + E + ++ LE ++ +K++ E+Q+ S K + +
Sbjct: 1241 GKLEELSNQLHRSQEEEGTQRKALEAQNEIHTKEKEKLIDKIQEMQEASDHLKKQFETES 1300
Query: 1539 KVKKQLRDLEAKV----KDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHS 1587
+VK R +++ +D EEELD + I+ L+ L + + HS
Sbjct: 1301 EVKCNFRQEASRLTLENRDLEEELDMKDRVIKKLQDQVKTLSKTIGKANDVHS 1353
Score = 57.4 bits (137), Expect = 1e-07
Identities = 46/208 (22%), Positives = 105/208 (50%), Gaps = 20/208 (9%)
Query: 1736 RLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQELQE 1795
R+QR +Q +LE+ ++ + L++K + A + D+ +I L+A+LE+A ++ +E
Sbjct: 890 RVQR----LQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEE 945
Query: 1796 KLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVK-RLESLASRLKENMEK 1854
K + + VE + AK+++ + LE ++ Q++ +L+ LKE M+
Sbjct: 946 KGKRYRDAVE-------------EKLAKLQKHNSELETQKEQIQLKLQEKTEELKEKMDN 992
Query: 1855 LTEERDQRIAAENREKE-QNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEA 1913
LT++ + E R++ K + + +D ++++ L + +K +L+ +E
Sbjct: 993 LTKQLFDDVQKEERQRMLLEKSFELKTQDYEKQIQSLKEEIKALKDEKMQLQHLVEGEHV 1052
Query: 1914 ANQSLQADLKLAFKRIGDLQAAIEDEME 1941
+ L+A++ K++ + + E E+E
Sbjct: 1053 TSDGLKAEVARLSKQVKTI-SEFEKEIE 1079
Score = 35.8 bits (81), Expect = 0.44
Identities = 33/152 (21%), Positives = 74/152 (48%), Gaps = 16/152 (10%)
Query: 1823 KIRELETRLEFERTQ----VKRLESLASRLKENMEKLTE-ERDQRIAAENREKEQNKRLQ 1877
+++ L+ +LE + + V++L SLA+ ++EK+ + E + AA +R + K
Sbjct: 890 RVQRLQKKLEDQNKENHGLVEKLTSLAALRAGDVEKIQKLEAELEKAATHRRNYEEK--G 947
Query: 1878 RQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIE 1937
++ RD EE K A+ + ELE E ++ Q +LK +++ +L +
Sbjct: 948 KRYRDAVEE------KLAKLQKHNSELETQKEQIQLKLQEKTEELK---EKMDNLTKQLF 998
Query: 1938 DEMESDENEDLINSEGDSDVDSELEDRVDGVK 1969
D+++ +E + ++ + + E ++ +K
Sbjct: 999 DDVQKEERQRMLLEKSFELKTQDYEKQIQSLK 1030
>gi|215982794 myosin VA isoform 2 [Homo sapiens]
Length = 1828
Score = 295 bits (756), Expect = 2e-79
Identities = 352/1534 (22%), Positives = 670/1534 (43%), Gaps = 237/1534 (15%)
Query: 340 IAAEEAWNETEKVWLVHRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILD--VDEDDVE 397
+AA E + + +VW+ + +++L + P KV + +G L+ +D E
Sbjct: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYK--PGDKVLLLHLEEGKDLEYHLDPKTKE 58
Query: 398 KANAPSCDRL---EDLASLVYLNESSVLHTLRQRY-GASLLHTYAGPSLLVLGPRGAPAV 453
+ + D L DL +L YL+E +VLH LR R+ + L++TY G L+ + P +
Sbjct: 59 LPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPI 118
Query: 454 YSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQ 513
Y E +++ + G DM PHI+AVA+ AY+ M ++QSII+ G SG+GKT S ++ ++
Sbjct: 119 YGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMR 178
Query: 514 YLATIAGISGNKVFSVEKWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASA 573
Y AT++G S ++ EK A ++E+ GN+ T N N++RF + + + FD+ ++ A
Sbjct: 179 YFATVSG-SASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGA 237
Query: 574 SIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPE 633
+++T LLEK RV + E +++FY L A L L + A+N + +
Sbjct: 238 NMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGN-ADNFNYTKQGGSPVI 296
Query: 634 EKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHE 693
E A++ + + A +LGIS Q + ILA I HLG G T A++ +HE
Sbjct: 297 EGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIP-PKHE 355
Query: 694 WAQKAAYLLGCSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLE 753
L+G EE+ + + L +T P KL A +
Sbjct: 356 PLCIFCDLMGVDYEEMCHWLCHRK-----LATATETYIKPIS---------KLQATNARD 401
Query: 754 GMAAGLYSELFTLLVSLVNRALKSS--QHSLCSMMIVDTPGFQNPEQGGSARGASFEELC 811
+A +Y++LF +V VN+AL S+ QHS ++D GF+ E SFE+ C
Sbjct: 402 ALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIG--VLDIYGFETFEIN------SFEQFC 453
Query: 812 HNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLA 871
NY ++LQ+ F+ F E E Y +E I +D +Q + +
Sbjct: 454 INYANEKLQQQFNMHVFKLEQEEYMKEQIPWTL-------------IDFYDNQPCINLI- 499
Query: 872 RTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGH 931
+ G+L LL+EE +P ++DT ++L++ + + L + +
Sbjct: 500 --ESKLGILDLLDEECKMPKGTDDTWAQKLYNTH-------LNKCALFEKPRLSNKAFII 550
Query: 932 SHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGL 991
H + VEY G+L K + + ++L+ S+ K++ LF +S + A
Sbjct: 551 QHFADKVEYQCEGFLEKNK-DTVFEEQIKVLKSSKFKMLPELF---QDDEKAISPTSATS 606
Query: 992 EGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVA 1051
G + L R K MA KK++ Q + + L++T+ + H+V C P
Sbjct: 607 SGRTPLT-RTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKP-- 663
Query: 1052 EGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQG 1111
++ P D QLR +L+ +R+ G
Sbjct: 664 ------------------NDFKFP---------FTFDEKRAVQQLRACGVLETIRISAAG 696
Query: 1112 YPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVF 1171
+P + EF R+ VL + ++ D ++ + +LE L L+K G +++F
Sbjct: 697 FPSRWTYQEFFSRYRVLMK-------QKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIF 749
Query: 1172 FRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHF---------KKRKIQDLAIRCVQ 1222
FRAG +A LE+ R ++ Q RG+L R+ + +R ++ RC
Sbjct: 750 FRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYA 809
Query: 1223 KNIKKNKGVK-DWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELR 1281
K +++ K +W+++ VR +++ + + R++ K +E +
Sbjct: 810 KFLRRTKAATIIQKYWRMY-VVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAV- 867
Query: 1282 LNSDRLESRISELTSELTDERNTGESASQLLDAETA-ERLRAEKEMKELQTQYDALKKQM 1340
++ R+ + +R S ++ + R+ A++E+K+L+ + ++++
Sbjct: 868 ----IIQKRVRGWLARTHYKR----SMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYK 919
Query: 1341 EV---MEMEVMEARLIRAAEINGEVDDDDAGGEWRLK--------YERAVREVDFTKKRL 1389
++ ME ++M ++ +VD+ + + ++ Y ++ +RL
Sbjct: 920 KLHIGMENKIM--------QLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERL 971
Query: 1390 QQEFEDKLEVEQQNKRQLERRLGDLQADSEES-------QRALQQLKKKCQRLTAEL-QD 1441
Q E++ +V L+ + L+ D E++ + + K++ ++L + L ++
Sbjct: 972 QLS-EEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEE 1030
Query: 1442 TKLHLEGQQVRNHEL--------EKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA 1493
L + ++ NH + E +++ E Q + E+L+ + L E L
Sbjct: 1031 NTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEE 1090
Query: 1494 EAFSLKQQL------------EEKDMDIAGFTQKVVSLE-AELQDISSQESK-------- 1532
LK+++ + ++ + S E AE++DI S+ +
Sbjct: 1091 RYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPL 1150
Query: 1533 DEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMES 1592
D + K++K++ +LE + + ++ELD + E+ LR + + E Q E+E
Sbjct: 1151 DMSLFLKLQKRVTELEQEKQVMQDELDRK-------EEQVLRSKAKEEERPQIRGAELEY 1203
Query: 1593 RDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREK-------------RELEGKLATL 1639
+ +E +S KKLK E + +K L EK R L +L ++
Sbjct: 1204 ESLKRQEL-ESENKKLK-------NELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSV 1255
Query: 1640 SDQVNRRDFESEKRLRKDL---------KRTKALLADAQLMLDHLKNSAPSKREIAQLKN 1690
S++++ R E LR L K K + D+ ++L+ ++ K EIAQ
Sbjct: 1256 SEELDVRK-EEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQ-KMKDKGEIAQAYI 1313
Query: 1691 QLEESEFTCAAAVKARK--------AMEVEIEDL-------------HLQIDDIAKAKTA 1729
L+E+ + ++++K A+ EI+ L +LQ+ A+ + +
Sbjct: 1314 GLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEAS 1373
Query: 1730 LEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHK 1763
L+ +++RL E ++ +LE+ + + +L K+ K
Sbjct: 1374 LQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLK 1407
Score = 76.6 bits (187), Expect = 2e-13
Identities = 122/576 (21%), Positives = 243/576 (42%), Gaps = 102/576 (17%)
Query: 1419 EESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE-----LEKKQRRFDSELSQAHEE 1473
+ S A+ L+ +R+ A+ + KL +E + V ++ +E K + ++ + +++
Sbjct: 883 KRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKD 942
Query: 1474 AQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD----------IAGFTQKVVSLEAEL 1523
K EKL + + +E L+ LE + + +++ L +L
Sbjct: 943 Y---KCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDL 999
Query: 1524 QDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTI--QMLEQAKLRLE-MEME 1580
+ S++ E + K++ L + +K++ L ++ + ++++QAK E ME +
Sbjct: 1000 EQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKK 1059
Query: 1581 RMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLR---------EKRE 1631
+ +T E++ DE R Q L + +LEE Y+D ++ + KR
Sbjct: 1060 LVEETKQLELDLNDE-----RLRYQNLLNEFS-RLEERYDDLKEEMTLMVHVPKPGHKRT 1113
Query: 1632 ------------LEGKLATLSDQVNRRDFESEKRLRKDL-------KRTKALLADAQLML 1672
++A + D +R + SEK++ D+ KR L + Q+M
Sbjct: 1114 DSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQ 1173
Query: 1673 DHLKNSAPSKREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEE 1732
D L ++E L+++ +E E + E+E E L Q LE
Sbjct: 1174 DEL-----DRKEEQVLRSKAKEEERPQI------RGAELEYESLKRQ---------ELES 1213
Query: 1733 QLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQIND-LQAQLEEANKEKQ 1791
+ +L+ E NE++ L E + E+ A L +++ L + EE +
Sbjct: 1214 ENKKLKNELNELRKALSE--KSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRS 1271
Query: 1792 ELQEKLQALQSQVE---------FLE--QSMVDKSLVSRQEAKIRELETRLEFERTQVKR 1840
+L + +A+Q + + LE Q M DK +++ ++E LE + KR
Sbjct: 1272 QLVSQKEAIQPKDDKNTMTDSTILLEDVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKR 1331
Query: 1841 L-ESLASRLKENMEKLTEE--RDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEA 1897
E+ A L+ ++ L EE R Q++ A+N + R++ L+ E+ R
Sbjct: 1332 SHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQH------EITR----L 1381
Query: 1898 SRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQ 1933
+ + +L LE + + L+ LK+ K+IG+L+
Sbjct: 1382 TNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1417
Score = 62.8 bits (151), Expect = 3e-09
Identities = 92/417 (22%), Positives = 170/417 (40%), Gaps = 65/417 (15%)
Query: 1625 VLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQ----LMLDHLKNSAP 1680
V+R + ++ + AT+ Q R F + R RK L+ KA++ + L H K S
Sbjct: 829 VVRRRYKIR-RAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887
Query: 1681 S-------------KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAK 1727
+ KRE+ +LK + E K ME +I L ++D+ K
Sbjct: 888 AIIYLQCCFRRMMAKRELKKLKIEARSVE----RYKKLHIGMENKIMQLQRKVDEQNKDY 943
Query: 1728 TALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEAN 1787
L E+L+ L+ N +L D E + ++ K A + +I L+ LE+
Sbjct: 944 KCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTR 1003
Query: 1788 KEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQE------------------------AK 1823
EK+ ++E + + E L ++ +++ + +QE +
Sbjct: 1004 SEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEE 1063
Query: 1824 IRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRI----AAENREKEQNKRLQRQ 1879
++LE L ER + + L + SRL+E + L EE + R + + +
Sbjct: 1064 TKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESE 1123
Query: 1880 LRDTKE--EMGELARKEAEASRKKHELEMDL--------ESLEAANQSLQADLKLAFKRI 1929
+ E EM ++ + E S KK L+M L LE Q +Q +L +++
Sbjct: 1124 YIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQV 1183
Query: 1930 GDLQAAIEDEME----SDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAA 1982
+A E+ + E E L E +S+ + +L++ ++ ++ LS+ P A
Sbjct: 1184 LRSKAKEEERPQIRGAELEYESLKRQELESE-NKKLKNELNELRKALSEKSAPEVTA 1239
Score = 50.8 bits (120), Expect = 1e-05
Identities = 145/675 (21%), Positives = 247/675 (36%), Gaps = 219/675 (32%)
Query: 1091 LLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDE---RR 1147
L + LR + M+ Y +GY +++F RR A + +K+ R Y+V RR
Sbjct: 782 LRKKYLRMRKAAITMQRYVRGYQARC-YAKFLRR--TKAATIIQKYWRMYVVRRRYKIRR 838
Query: 1148 AVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQH 1207
A +L+ + G LAR R + Q RG+LAR H
Sbjct: 839 AATIVLQS----------------YLRGFLAR-NRYRKILREHKAVIIQKRVRGWLARTH 881
Query: 1208 FK------------------KRKIQDLAI------------------------------- 1218
+K KR+++ L I
Sbjct: 882 YKRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNK 941
Query: 1219 --RCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLSEEQIR-------NKDEEIQQLRSK 1269
+C+ + + +G+ + KL + + L QLSEE+ + + EEI +LR
Sbjct: 942 DYKCLVEKLTNLEGIYNSETEKLRSDLERL---QLSEEEAKVATGRVLSLQEEIAKLRKD 998
Query: 1270 LEKAEKERNELRLNSDRLESRISELTSELTDE-------------------RNTGESASQ 1310
LE+ E+ + ++DR + +L S L +E + E+ +
Sbjct: 999 LEQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEK 1058
Query: 1311 LLDAETA--------ERLRAEK---EMKELQTQYDALKKQMEVM-------------EME 1346
L ET ERLR + E L+ +YD LK++M +M
Sbjct: 1059 KLVEETKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHS 1118
Query: 1347 VMEARLIRAAEINGEVDDDDAGGEWR------------LKYERAVREVDFTKKRLQQEFE 1394
E+ I ++EI E++D + E LK ++ V E++ K+ +Q E +
Sbjct: 1119 SNESEYIFSSEI-AEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELD 1177
Query: 1395 DK---------------------LEVEQQNKRQLERRLGDLQADSEESQRALQQ------ 1427
K LE E +++LE L+ + E ++AL +
Sbjct: 1178 RKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEKSAPEV 1237
Query: 1428 ----------LKKKCQRLTAELQDTK---LHLEGQQVRNHE-----------------LE 1457
L ++ ++ EL K L L Q V E LE
Sbjct: 1238 TAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLE 1297
Query: 1458 KKQRRFDS-ELSQAH---EEAQR---EKLQREKL--QREKDMLLAEAFSLK------QQL 1502
Q+ D E++QA+ +E R +LQ +K + E + L E SLK QQL
Sbjct: 1298 DVQKMKDKGEIAQAYIGLKETNRLLESQLQSQKRSHENEAEALRGEIQSLKEENNRQQQL 1357
Query: 1503 EEKDMDI-------AGFTQKVVSLEAELQDISSQESKDEASLAKVKKQLRDLEAKVKDQE 1555
+++ + A ++ L E D+ Q K + ++ K+KKQL+ K+ + E
Sbjct: 1358 LAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1417
Query: 1556 EELDEQAGTIQMLEQ 1570
E Q++++
Sbjct: 1418 VGQMENISPGQIIDE 1432
>gi|215982791 myosin VA isoform 1 [Homo sapiens]
Length = 1855
Score = 294 bits (753), Expect = 5e-79
Identities = 364/1580 (23%), Positives = 684/1580 (43%), Gaps = 237/1580 (15%)
Query: 340 IAAEEAWNETEKVWLVHRDGFSLASQLKSEELNLPEGKVRVKLDHDGAILD--VDEDDVE 397
+AA E + + +VW+ + +++L + P KV + +G L+ +D E
Sbjct: 1 MAASELYTKFARVWIPDPEEVWKSAELLKDYK--PGDKVLLLHLEEGKDLEYHLDPKTKE 58
Query: 398 KANAPSCDRL---EDLASLVYLNESSVLHTLRQRY-GASLLHTYAGPSLLVLGPRGAPAV 453
+ + D L DL +L YL+E +VLH LR R+ + L++TY G L+ + P +
Sbjct: 59 LPHLRNPDILVGENDLTALSYLHEPAVLHNLRVRFIDSKLIYTYCGIVLVAINPYEQLPI 118
Query: 454 YSEKVMHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQ 513
Y E +++ + G DM PHI+AVA+ AY+ M ++QSII+ G SG+GKT S ++ ++
Sbjct: 119 YGEDIINAYSGQNMGDMDPHIFAVAEEAYKQMARDERNQSIIVSGESGAGKTVSAKYAMR 178
Query: 514 YLATIAGISGNKVFSVEKWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASA 573
Y AT++G S ++ EK A ++E+ GN+ T N N++RF + + + FD+ ++ A
Sbjct: 179 YFATVSG-SASEANVEEKVLASNPIMESIGNAKTTRNDNSSRFGKYIEIGFDKRYRIIGA 237
Query: 574 SIQTMLLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPE 633
+++T LLEK RV + E +++FY L A L L + A+N + +
Sbjct: 238 NMRTYLLEKSRVVFQAEEERNYHIFYQLCASAKLPEFKMLRLGN-ADNFNYTKQGGSPVI 296
Query: 634 EKQKAAQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHE 693
E A++ + + A +LGIS Q + ILA I HLG G T A++ +HE
Sbjct: 297 EGVDDAKEMAHTRQACTLLGISESHQMGIFRILAGILHLGNVGFTSRDADSCTIP-PKHE 355
Query: 694 WAQKAAYLLGCSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLE 753
L+G EE+ + + L +T P KL A +
Sbjct: 356 PLCIFCDLMGVDYEEMCHWLCHRK-----LATATETYIKPIS---------KLQATNARD 401
Query: 754 GMAAGLYSELFTLLVSLVNRALKSS--QHSLCSMMIVDTPGFQNPEQGGSARGASFEELC 811
+A +Y++LF +V VN+AL S+ QHS ++D GF+ E SFE+ C
Sbjct: 402 ALAKHIYAKLFNWIVDNVNQALHSAVKQHSFIG--VLDIYGFETFEIN------SFEQFC 453
Query: 812 HNYTQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLA 871
NY ++LQ+ F+ F E E Y +E I +D +Q + +
Sbjct: 454 INYANEKLQQQFNMHVFKLEQEEYMKEQIPWTL-------------IDFYDNQPCINLI- 499
Query: 872 RTDEARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGH 931
+ G+L LL+EE +P ++DT ++L++ + + L + +
Sbjct: 500 --ESKLGILDLLDEECKMPKGTDDTWAQKLYNTH-------LNKCALFEKPRLSNKAFII 550
Query: 932 SHGTNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGL 991
H + VEY G+L K + + ++L+ S+ K++ LF +S + A
Sbjct: 551 QHFADKVEYQCEGFLEKNK-DTVFEEQIKVLKSSKFKMLPELF---QDDEKAISPTSATS 606
Query: 992 EGGSQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVA 1051
G + L R K MA KK++ Q + + L++T+ + H+V C P
Sbjct: 607 SGRTPLT-RTPAKPTKGRPGQMAKEHKKTVGHQFRNSLHLLMETLNATTPHYVRCIKP-- 663
Query: 1052 EGWAGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQG 1111
++ P D QLR +L+ +R+ G
Sbjct: 664 ------------------NDFKFP---------FTFDEKRAVQQLRACGVLETIRISAAG 696
Query: 1112 YPDHMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVF 1171
+P + EF R+ VL + ++ D ++ + +LE L L+K G +++F
Sbjct: 697 FPSRWTYQEFFSRYRVLMK-------QKDVLSDRKQTCKNVLEKLILDKDKYQFGKTKIF 749
Query: 1172 FRAGTLARLEEQRDEQTSRNLTLFQAACRGYLARQHF---------KKRKIQDLAIRCVQ 1222
FRAG +A LE+ R ++ Q RG+L R+ + +R ++ RC
Sbjct: 750 FRAGQVAYLEKLRADKLRAACIRIQKTIRGWLLRKKYLRMRKAAITMQRYVRGYQARCYA 809
Query: 1223 KNIKKNKGVK-DWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELR 1281
K +++ K +W+++ VR +++ + + R++ K +E +
Sbjct: 810 KFLRRTKAATIIQKYWRMY-VVRRRYKIRRAATIVLQSYLRGFLARNRYRKILREHKAV- 867
Query: 1282 LNSDRLESRISELTSELTDERNTGESASQLLDAETA-ERLRAEKEMKELQTQYDALKKQM 1340
++ R+ + +R S ++ + R+ A++E+K+L+ + ++++
Sbjct: 868 ----IIQKRVRGWLARTHYKR----SMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYK 919
Query: 1341 EV---MEMEVMEARLIRAAEINGEVDDDDAGGEWRLK--------YERAVREVDFTKKRL 1389
++ ME ++M ++ +VD+ + + ++ Y ++ +RL
Sbjct: 920 KLHIGMENKIM--------QLQRKVDEQNKDYKCLVEKLTNLEGIYNSETEKLRSDLERL 971
Query: 1390 QQEFEDKLEVEQQNKRQLERRLGDLQADSEES-------QRALQQLKKKCQRLTAEL-QD 1441
Q E++ +V L+ + L+ D E++ + + K++ ++L + L ++
Sbjct: 972 QLS-EEEAKVATGRVLSLQEEIAKLRKDLEQTRSEKKCIEEHADRYKQETEQLVSNLKEE 1030
Query: 1442 TKLHLEGQQVRNHEL--------EKKQRRFDSELSQAHEEAQREKLQREKLQREKDMLLA 1493
L + ++ NH + E +++ E Q + E+L+ + L E L
Sbjct: 1031 NTLLKQEKEALNHRIVQQAKEMTETMEKKLVEETKQLELDLNDERLRYQNLLNEFSRLEE 1090
Query: 1494 EAFSLKQQL------------EEKDMDIAGFTQKVVSLE-AELQDISSQESK-------- 1532
LK+++ + ++ + S E AE++DI S+ +
Sbjct: 1091 RYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPL 1150
Query: 1533 DEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMES 1592
D + K++K++ +LE + + ++ELD + E+ LR + + E Q E+E
Sbjct: 1151 DMSLFLKLQKRVTELEQEKQVMQDELDRK-------EEQVLRSKAKEEERPQIRGAELEY 1203
Query: 1593 RDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREK-------------RELEGKLATL 1639
+ +E +S KKLK E + +K L EK R L +L ++
Sbjct: 1204 ESLKRQEL-ESENKKLK-------NELNELRKALSEKSAPEVTAPGAPAYRVLMEQLTSV 1255
Query: 1640 SDQVNRRDFESEKRLRKDL---------KRTKALLADAQLMLDHLKNSAPSKREIAQLKN 1690
S++++ R E LR L K K + D+ ++L+ ++ K EIAQ
Sbjct: 1256 SEELDVRK-EEVLILRSQLVSQKEAIQPKDDKNTMTDSTILLEDVQ-KMKDKGEIAQAYI 1313
Query: 1691 QLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQRE--------KN 1742
L+E+ + A E +L L + + +A LE QL +R +
Sbjct: 1314 GLKETNRSSALDYHELN----EDGELWLVYEGLKQANRLLESQLQSQKRSHENEAEALRG 1369
Query: 1743 EIQNRLEEDQEDMNELMK--------KHKAAVAQASRDLAQIN-DLQAQLEEANKEKQEL 1793
EIQ+ EE+ L + + +A++ L N DL QLE+ +K ++L
Sbjct: 1370 EIQSLKEENNRQQQLLAQNLQLPPEARIEASLQHEITRLTNENLDLMEQLEKQDKTVRKL 1429
Query: 1794 QEKLQALQSQVEFLEQSMVD 1813
+++L+ ++ LE ++
Sbjct: 1430 KKQLKVFAKKIGELEVGQME 1449
Score = 65.5 bits (158), Expect = 5e-10
Identities = 121/590 (20%), Positives = 246/590 (41%), Gaps = 103/590 (17%)
Query: 1419 EESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHE-----LEKKQRRFDSELSQAHEE 1473
+ S A+ L+ +R+ A+ + KL +E + V ++ +E K + ++ + +++
Sbjct: 883 KRSMHAIIYLQCCFRRMMAKRELKKLKIEARSVERYKKLHIGMENKIMQLQRKVDEQNKD 942
Query: 1474 AQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMD----------IAGFTQKVVSLEAEL 1523
K EKL + + +E L+ LE + + +++ L +L
Sbjct: 943 Y---KCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDL 999
Query: 1524 QDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTI--QMLEQAKLRLE-MEME 1580
+ S++ E + K++ L + +K++ L ++ + ++++QAK E ME +
Sbjct: 1000 EQTRSEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKK 1059
Query: 1581 RMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLR---------EKRE 1631
+ +T E++ DE R Q L + +LEE Y+D ++ + KR
Sbjct: 1060 LVEETKQLELDLNDE-----RLRYQNLLNEFS-RLEERYDDLKEEMTLMVHVPKPGHKRT 1113
Query: 1632 ------------LEGKLATLSDQVNRRDFESEKRLRKDL-------KRTKALLADAQLML 1672
++A + D +R + SEK++ D+ KR L + Q+M
Sbjct: 1114 DSTHSSNESEYIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQ 1173
Query: 1673 DHLKNSAPSKREIAQLKNQLEESEFTCAAAVK----ARKAMEVEIEDLHLQIDDIAKAKT 1728
D L + ++ + K + EE A ++ R+ +E E + L +++++ KA +
Sbjct: 1174 DELDRK---EEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALS 1230
Query: 1729 -------------ALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQ 1775
A + +L E+ R EE ++L+ + +A Q D
Sbjct: 1231 EKSAPEVTAPGAPAYRVLMEQLTSVSEELDVRKEEVLILRSQLVSQKEAI--QPKDDKNT 1288
Query: 1776 INDLQAQLEEANKEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQ----------EAKIR 1825
+ D LE+ K K + E QA E S +D ++ + R
Sbjct: 1289 MTDSTILLEDVQKMKDK-GEIAQAYIGLKETNRSSALDYHELNEDGELWLVYEGLKQANR 1347
Query: 1826 ELETRLEFERTQVKRLESLASRLKENMEKLTEE--RDQRIAAENREKEQNKRLQRQLRDT 1883
LE++L+ +Q + E+ A L+ ++ L EE R Q++ A+N + R++ L+
Sbjct: 1348 LLESQLQ---SQKRSHENEAEALRGEIQSLKEENNRQQQLLAQNLQLPPEARIEASLQH- 1403
Query: 1884 KEEMGELARKEAEASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQ 1933
E+ R + + +L LE + + L+ LK+ K+IG+L+
Sbjct: 1404 -----EITR----LTNENLDLMEQLEKQDKTVRKLKKQLKVFAKKIGELE 1444
Score = 62.8 bits (151), Expect = 3e-09
Identities = 92/417 (22%), Positives = 170/417 (40%), Gaps = 65/417 (15%)
Query: 1625 VLREKRELEGKLATLSDQVNRRDFESEKRLRKDLKRTKALLADAQ----LMLDHLKNSAP 1680
V+R + ++ + AT+ Q R F + R RK L+ KA++ + L H K S
Sbjct: 829 VVRRRYKIR-RAATIVLQSYLRGFLARNRYRKILREHKAVIIQKRVRGWLARTHYKRSMH 887
Query: 1681 S-------------KREIAQLKNQLEESEFTCAAAVKARKAMEVEIEDLHLQIDDIAKAK 1727
+ KRE+ +LK + E K ME +I L ++D+ K
Sbjct: 888 AIIYLQCCFRRMMAKRELKKLKIEARSVE----RYKKLHIGMENKIMQLQRKVDEQNKDY 943
Query: 1728 TALEEQLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEAN 1787
L E+L+ L+ N +L D E + ++ K A + +I L+ LE+
Sbjct: 944 KCLVEKLTNLEGIYNSETEKLRSDLERLQLSEEEAKVATGRVLSLQEEIAKLRKDLEQTR 1003
Query: 1788 KEKQELQEKLQALQSQVEFLEQSMVDKSLVSRQE------------------------AK 1823
EK+ ++E + + E L ++ +++ + +QE +
Sbjct: 1004 SEKKCIEEHADRYKQETEQLVSNLKEENTLLKQEKEALNHRIVQQAKEMTETMEKKLVEE 1063
Query: 1824 IRELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRI----AAENREKEQNKRLQRQ 1879
++LE L ER + + L + SRL+E + L EE + R + + +
Sbjct: 1064 TKQLELDLNDERLRYQNLLNEFSRLEERYDDLKEEMTLMVHVPKPGHKRTDSTHSSNESE 1123
Query: 1880 LRDTKE--EMGELARKEAEASRKKHELEMDL--------ESLEAANQSLQADLKLAFKRI 1929
+ E EM ++ + E S KK L+M L LE Q +Q +L +++
Sbjct: 1124 YIFSSEIAEMEDIPSRTEEPSEKKVPLDMSLFLKLQKRVTELEQEKQVMQDELDRKEEQV 1183
Query: 1930 GDLQAAIEDEME----SDENEDLINSEGDSDVDSELEDRVDGVKSWLSKNKGPSKAA 1982
+A E+ + E E L E +S+ + +L++ ++ ++ LS+ P A
Sbjct: 1184 LRSKAKEEERPQIRGAELEYESLKRQELESE-NKKLKNELNELRKALSEKSAPEVTA 1239
Score = 48.1 bits (113), Expect = 9e-05
Identities = 76/335 (22%), Positives = 143/335 (42%), Gaps = 62/335 (18%)
Query: 1248 EVQLSEEQI---RNKDEEIQQLR-SKLEKAEKERNELRLNSDRLESRISELTSELTDERN 1303
E+ EEQ+ + K+EE Q+R ++LE +R EL + +L++ ++EL L+++
Sbjct: 1175 ELDRKEEQVLRSKAKEEERPQIRGAELEYESLKRQELESENKKLKNELNELRKALSEK-- 1232
Query: 1304 TGESASQLLDAETAERLRAEKEMKELQTQYDALKKQMEVMEMEVM--EARLIRAAEINGE 1361
SA ++ TA A + + E Q ++ ++++V + EV+ ++L+ E
Sbjct: 1233 ---SAPEV----TAPGAPAYRVLME---QLTSVSEELDVRKEEVLILRSQLVSQKEAIQP 1282
Query: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQ------QNKRQLERRLGDLQ 1415
DD + + + E Q+ +DK E+ Q + R +L
Sbjct: 1283 KDDKNTMTDSTILLEDV------------QKMKDKGEIAQAYIGLKETNRSSALDYHELN 1330
Query: 1416 ADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAHEEAQ 1475
D E + LK+ + L ++LQ K R+HE E + R E+ EE
Sbjct: 1331 EDGE-LWLVYEGLKQANRLLESQLQSQK--------RSHENEAEALR--GEIQSLKEENN 1379
Query: 1476 REKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAELQDISSQESKDEA 1535
R++ LLA+ L + + A ++ L E D+ Q K +
Sbjct: 1380 RQQ-----------QLLAQNLQLPPEARIE----ASLQHEITRLTNENLDLMEQLEKQDK 1424
Query: 1536 SLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQ 1570
++ K+KKQL+ K+ + E E Q++++
Sbjct: 1425 TVRKLKKQLKVFAKKIGELEVGQMENISPGQIIDE 1459
>gi|122937345 myosin VB [Homo sapiens]
Length = 1848
Score = 286 bits (732), Expect = 1e-76
Identities = 366/1618 (22%), Positives = 682/1618 (42%), Gaps = 226/1618 (13%)
Query: 344 EAWNETEKVWLVHRDGFSLASQLKSEELNLPEGKVRVKLDHDGAI---LDVDEDDVEKAN 400
E +++ +VW+ D +++L +++ + ++++L+ + + +DV + +
Sbjct: 5 ELYSQCTRVWIPDPDEVWRSAEL-TKDYKEGDKSLQLRLEDETILEYPIDVQRNQLPFLR 63
Query: 401 APSCDRLE-DLASLVYLNESSVLHTLRQRY-GASLLHTYAGPSLLVLGPRGAPAVYSEKV 458
P E DL +L YL+E +VLH L+ R+ ++ ++TY G L+ + P +Y + V
Sbjct: 64 NPDILVGENDLTALSYLHEPAVLHNLKVRFLESNHIYTYCGIVLVAINPYEQLPIYGQDV 123
Query: 459 MHMFKGCRREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATI 518
++ + G DM PHI+AVA+ AY+ M ++QSII+ G SG+GKT S ++ ++Y AT+
Sbjct: 124 IYTYSGQNMGDMDPHIFAVAEEAYKQMARDEKNQSIIVSGESGAGKTVSAKYAMRYFATV 183
Query: 519 AGISGNKVFSVEKWQALYTLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTM 578
G S ++ EK A ++EA GN+ T N N++RF + + + FD+ + A+++T
Sbjct: 184 GG-SASETNIEEKVLASSPIMEAIGNAKTTRNDNSSRFGKYIQIGFDKRYHIIGANMRTY 242
Query: 579 LLEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKA 638
LLEK RV + E +++FY L A EL L AE+ + E
Sbjct: 243 LLEKSRVVFQADDERNYHIFYQLCAAAGLPEFKELALTS-AEDFFYTSQGGDTSIEGVDD 301
Query: 639 AQQFSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKA 698
A+ F K + A +LG+ Q + + I+A+I HLG+ E + +
Sbjct: 302 AEDFEKTRQAFTLLGVKESHQMSIFKIIASILHLGSVAIQAERDGDSCSISPQDVYLSNF 361
Query: 699 AYLLGCSLEELSSAIF--KHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMA 756
LLG ++ + K T ++ S +Q + +A
Sbjct: 362 CRLLGVEHSQMEHWLCHRKLVTTSETYVKTMSLQQ----------------VINARNALA 405
Query: 757 AGLYSELFTLLVSLVNRALKSS--QHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNY 814
+Y++LF +V +N+AL +S QHS ++D GF+ E SFE+ C NY
Sbjct: 406 KHIYAQLFGWIVEHINKALHTSLKQHSFIG--VLDIYGFETFEVN------SFEQFCINY 457
Query: 815 TQDRLQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTD 874
++LQ+ F+ F E E Y +E I D D+ +D +
Sbjct: 458 ANEKLQQQFNSHVFKLEQEEYMKEQIPWTLIDFY----DNQPCID------------LIE 501
Query: 875 EARGLLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHG 934
G+L LL+EE VP ++ ++L Y + Q P + ++ F++ H
Sbjct: 502 AKLGILDLLDEECKVPKGTDQNWAQKL---YDRHSSSQHFQKPRMSNTA---FII--VHF 553
Query: 935 TNWVEYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGG 994
+ VEY G+L ++ + +L+ S+ ++++LF + + G
Sbjct: 554 ADKVEYLSDGFLE-KNRDTVYEEQINILKASKFPLVADLF---HDDKDPVPATTPGKGSS 609
Query: 995 SQLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGW 1054
S++++R A K KK++ Q + + L++T+ + H+V C P
Sbjct: 610 SKISVRSARPPMKVSN----KEHKKTVGHQFRTSLHLLMETLNATTPHYVRCIKP----- 660
Query: 1055 AGEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPD 1114
++ LP D QLR +L+ +R+ GYP
Sbjct: 661 ---------------NDEKLP---------FHFDPKRAVQQLRACGVLETIRISAAGYPS 696
Query: 1115 HMVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRA 1174
+ +F R+ V L KK R D++ +LE L + G +++FFRA
Sbjct: 697 RWAYHDFFNRYRV----LVKK--RELANTDKKAICRSVLENLIKDPDKFQFGRTKIFFRA 750
Query: 1175 GTLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDW 1234
G +A LE+ R ++ + Q RG+L + + + K L ++
Sbjct: 751 GQVAYLEKLRADKFRTATIMIQKTVRGWLQKVKYHRLKGATLTLQ--------------- 795
Query: 1235 PWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISEL 1294
R + +L+E R + + Q ++++A + +R R I
Sbjct: 796 ------RYCRGHLARRLAEHLRRIRAAVVLQKHYRMQRARQAYQRVR----RAAVVIQAF 845
Query: 1295 TSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDA------------LKKQMEV 1342
T + R + + + +R + Q DA +++++
Sbjct: 846 TRAMFVRRTYRQVLMEHKATTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELKA 905
Query: 1343 MEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQ 1402
+ +E A ++ + E ++ +R + E + K L ++
Sbjct: 906 LRIEARSAEHLKRLNVGME--------NKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTM 957
Query: 1403 NKRQLERRLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRN-HELEK--- 1458
+L++ L Q E +L+++ + L ELQ + H E + + + H EK
Sbjct: 958 EVERLKKELVHYQQSPGEDTSL--RLQEEVESLRTELQ--RAHSERKILEDAHSREKDEL 1013
Query: 1459 KQRRFDSELSQAHEEAQREKLQREKLQREKDMLLAEAFS---LKQQLEEKDMDIAGFTQK 1515
++R D E A + ++E+L + L + KD + +K++LEE+ ++
Sbjct: 1014 RKRVADLEQENALLKDEKEQLNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKE 1073
Query: 1516 VVSLEAELQDISSQES--KDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKL 1573
LE ++ + + K + LE+ E T L+Q +
Sbjct: 1074 YSQLEQRYDNLRDEMTIIKQTPGHRRNPSNQSSLESDSNYPSISTSEIGDTEDALQQVE- 1132
Query: 1574 RLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEE-EYEDKQKVLREKREL 1632
+ +E M T +++ R E+E+ R K+++VQLE+ E +D +KV E +
Sbjct: 1133 EIGLEKAAMDMTVFLKLQKRVRELEQER-------KKLQVQLEKREQQDSKKVQAEPPQT 1185
Query: 1633 EGKLATLSD----QVNRRDFESE-KRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQ 1687
+ L +D + R++ ESE K+L+ DL + +AD Q ++ + +P +
Sbjct: 1186 DIDLDPNADLAYNSLKRQELESENKKLKNDLNELRKAVAD-QATQNNSSHGSPDSYSL-- 1242
Query: 1688 LKNQLEESEFTCAAAVKARKAMEVEIED---LHLQIDDIAKAKTALEEQLSRLQREKNEI 1744
L NQL+ A + +EV E+ L QI + + A + +
Sbjct: 1243 LLNQLK----------LAHEELEVRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWP 1292
Query: 1745 QNRLEEDQEDMNELMK---------------KHKAAVAQASRDLAQINDLQAQLEEANKE 1789
+ DQED E + A + L Q+ A+L EA +
Sbjct: 1293 NSEKHVDQEDAIEAYHGVCQTNSKTEDWGYLNEDGELGLAYQGLKQV----ARLLEAQLQ 1348
Query: 1790 KQEL--QEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEF-ERTQVKRLESLAS 1846
Q L +E+++ L++Q+E L++ M DK + + + E ++EF + ++ RL +
Sbjct: 1349 AQSLEHEEEVEHLKAQLEALKEEM-DKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENL 1407
Query: 1847 RLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHEL 1904
LKE +EKL E E++ K+L+ ++ K + E A+ A++ RK+HEL
Sbjct: 1408 DLKELVEKL----------EKNERKLKKQLKIYMK--KAQDLEAAQALAQSERKRHEL 1453
Score = 80.5 bits (197), Expect = 2e-14
Identities = 136/666 (20%), Positives = 280/666 (42%), Gaps = 87/666 (13%)
Query: 1193 TLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKLFTTVRPLIEVQLS 1252
T Q RG++AR+HF++ + + I+C + +K + +K +R IE + +
Sbjct: 865 TTIQKHVRGWMARRHFQRLRDAAIVIQCAFRMLKARRELK---------ALR--IEARSA 913
Query: 1253 EEQIR---NKDEEIQQLRSKLEKAEKE----RNELRLNSDRLESRISELTSELTD-ERNT 1304
E R + ++ QL+ K+++ KE +L + + + L EL +++
Sbjct: 914 EHLKRLNVGMENKVVQLQRKIDEQNKEFKTLSEQLSVTTSTYTMEVERLKKELVHYQQSP 973
Query: 1305 GESASQLLDAET----AERLRAEKEMKELQTQYDALKKQM--EVMEMEVMEARLIRAAE- 1357
GE S L E E RA E K L+ + K ++ V ++E A L E
Sbjct: 974 GEDTSLRLQEEVESLRTELQRAHSERKILEDAHSREKDELRKRVADLEQENALLKDEKEQ 1033
Query: 1358 INGEV--DDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQ--NKRQ----LER 1409
+N ++ D + +K +E++ + R Q ++ ++EQ+ N R +++
Sbjct: 1034 LNNQILCQSKDEFAQNSVKENLMKKELEEERSRYQNLVKEYSQLEQRYDNLRDEMTIIKQ 1093
Query: 1410 RLGDLQADSEESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQR------RF 1463
G + S +S +L+ T+E+ DT+ L QQV LEK +
Sbjct: 1094 TPGHRRNPSNQS--SLESDSNYPSISTSEIGDTEDAL--QQVEEIGLEKAAMDMTVFLKL 1149
Query: 1464 DSELSQAHEEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGFTQKVVSLEAEL 1523
+ + +E ++ ++Q EK +++ S K Q E DI + A+L
Sbjct: 1150 QKRVRELEQERKKLQVQLEKREQQD--------SKKVQAEPPQTDID------LDPNADL 1195
Query: 1524 QDISSQESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMR 1583
S + + E+ K+K L +L V DQ + + G+ +L++ E +
Sbjct: 1196 AYNSLKRQELESENKKLKNDLNELRKAVADQATQNNSSHGSPDSYSLLLNQLKLAHEELE 1255
Query: 1584 QTHSKEMESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSDQV 1643
+ + R + V ++ + + + + + +K + ++ +E
Sbjct: 1256 VRKEEVLILRTQIVSADQRRLAGRNAEPNINARSSWPNSEKHVDQEDAIEAYHGVCQTNS 1315
Query: 1644 NRRDF-----ESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFT 1698
D+ + E L + A L +AQL L++ + E+ LK QLE
Sbjct: 1316 KTEDWGYLNEDGELGLAYQGLKQVARLLEAQLQAQSLEH----EEEVEHLKAQLE----- 1366
Query: 1699 CAAAVKARKAMEVEIEDLHLQIDDIAKAKTALEEQLSRLQREKNEIQNRLEEDQEDMNEL 1758
A+K + + L + A+ + +++++SRL E +++ +E+ +++ +L
Sbjct: 1367 ---ALKEEMDKQQQTFCQTLLLSPEAQVEFGVQQEISRLTNENLDLKELVEKLEKNERKL 1423
Query: 1759 MKKHKAAVAQASRDLAQINDLQA--QLEEANKEKQELQEKLQALQSQVEF---LEQSMVD 1813
K+ K + +A DL+A L ++ +++ EL ++ + + +F LE D
Sbjct: 1424 KKQLKIYMKKA-------QDLEAAQALAQSERKRHELNRQVTVQRKEKDFQGMLEYHKED 1476
Query: 1814 KSLVSR 1819
++L+ R
Sbjct: 1477 EALLIR 1482
>gi|154354979 myosin X [Homo sapiens]
Length = 2058
Score = 228 bits (582), Expect = 4e-59
Identities = 254/1035 (24%), Positives = 445/1035 (42%), Gaps = 168/1035 (16%)
Query: 407 LEDLASLVYLNESSVLHTLRQRYGASLLHTYAGPSLLVLGP-RGAPAVYSEKVMHMFKGC 465
++D+ASL L+ S+++ L QRY + ++TY G L + P + +Y M +
Sbjct: 65 VDDMASLTELHGGSIMYNLFQRYKRNQIYTYIGSILASVNPYQPIAGLYEPATMEQYSRR 124
Query: 466 RREDMAPHIYAVAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGIS--- 522
++ PHI+A+A YR + +Q I++ G SG+GKT S + ++++L+ I+ S
Sbjct: 125 HLGELPPHIFAIANECYRCLWKRHDNQCILISGESGAGKTESTKLILKFLSVISQQSLEL 184
Query: 523 --GNKVFSVEKWQALYT-LLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTML 579
K VE+ + ++EAFGN+ T+ N N++RF + + L+ Q G + I L
Sbjct: 185 SLKEKTSCVERAILESSPIMEAFGNAKTVYNNNSSRFGKFVQLNICQKGNIQGGRIVDYL 244
Query: 580 LEKLRVARRPASEATFNVFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAA 639
LEK RV R+ E +++FY LLA + R E +L+ N + E+K +
Sbjct: 245 LEKNRVVRQNPGERNYHIFYALLAGLEHEEREEFYLS--TPENYHYLNQSGCVEDKTISD 302
Query: 640 QQ-FSKLQAAMKVLGISPDEQKACWFILAAIYHLGAAGATKEAAEAGRKQFARHEWAQKA 698
Q+ F ++ AM V+ S +E + +LA I HLG E AG Q + ++
Sbjct: 303 QESFREVITAMDVMQFSKEEVREVSRLLAGILHLG----NIEFITAGGAQVSFKTALGRS 358
Query: 699 AYLLGCSLEELSSAIFKHQHKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAG 758
A LLG +L+ A+ QRS R + L A++ + +A
Sbjct: 359 AELLGLDPTQLTDAL---------TQRSMFLRGEEILTPLN-----VQQAVDSRDSLAMA 404
Query: 759 LYSELFTLLVSLVNRALKSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDR 818
LY+ F ++ +N +K ++ S+ I+D GF+N E FE+ NY ++
Sbjct: 405 LYACCFEWVIKKINSRIKGNE-DFKSIGILDIFGFENFEVN------HFEQFNINYANEK 457
Query: 819 LQRLFHERTFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARG 878
LQ F++ F E Y E L ++D++ +D L+ ++ G
Sbjct: 458 LQEYFNKHIFSLEQLEYSREG--LVWEDID--------WIDNGECLDLI------EKKLG 501
Query: 879 LLWLLEEEALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWV 938
LL L+ EE+ P A++ TLLE+L S + K + + + G H V
Sbjct: 502 LLALINEESHFPQATDSTLLEKLHSQHANNHFYVKPRVAVNN--------FGVKHYAGEV 553
Query: 939 EYNVTGWLNYTKQNPATQNAPRLLQDSQKKIISNLF---LGRAGSATVLSGSIAGLEGGS 995
+Y+V G L ++ + LL++S+ I +LF R T+ GS
Sbjct: 554 QYDVRGILE-KNRDTFRDDLLNLLRESRFDFIYDLFEHVSSRNNQDTLKCGS-------- 604
Query: 996 QLALRRATSMRKTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWA 1055
++ ++ Q K + +L+ T+ S FV C P +
Sbjct: 605 -------------------KHRRPTVSSQFKDSLHSLMATLSSSNPFFVRCIKPNMQ--- 642
Query: 1056 GEPRSASSRRVSSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDH 1115
+P Q D ++ QLR S +L+ +R+ + GY
Sbjct: 643 -----------------KMPD---------QFDQAVVLNQLRYSGMLETVRIRKAGYAVR 676
Query: 1116 MVFSEFRRRFDVLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAG 1175
F +F +R+ VL +L + D R LL+ D S +G ++VF R
Sbjct: 677 RPFQDFYKRYKVLMRNLA-------LPEDVRGKCTSLLQLYDASNSEWQLGKTKVFLRES 729
Query: 1176 TLARLEEQRDEQTSRNLTLFQAACRGYLARQHFKK---------RKIQDLAIRCVQKNIK 1226
+LE++R+E+ S + +A G+LAR+ ++K + + +R ++K
Sbjct: 730 LEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVIIQKNYRAFLLRRRFLHLK 789
Query: 1227 KNKGV--KDWPWWKLFTTVRPLIEVQLSEEQIRNKDEEIQQLRSKLEK-AEKERNELRLN 1283
K V K R L+ + +E+ + ++EE ++ R + E+ E+ER E L
Sbjct: 790 KAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQEEEEKKKREEEERERERERREAELR 849
Query: 1284 SD-----RLESRISELTSELTDERNTGESASQLLDAETAERLRAEKEMKELQTQYDALKK 1338
+ R + + L + T E Q + + E LR EKE+++LQ +
Sbjct: 850 AQQEEETRKQQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIEDLQ-------R 902
Query: 1339 QMEVMEMEVMEARLIRAAEINGEVDDDDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLE 1398
E E+ + EA L + E + ++ +R ++ R QEF + L
Sbjct: 903 MKEQQELSLTEASLQKLQE----------------RRDQELRRLEEEACRAAQEFLESLN 946
Query: 1399 VEQQNK--RQLERRL 1411
++ ++ R +ER L
Sbjct: 947 FDEIDECVRNIERSL 961
Score = 49.7 bits (117), Expect = 3e-05
Identities = 57/263 (21%), Positives = 118/263 (44%), Gaps = 31/263 (11%)
Query: 1365 DDAGGEWRLKYERAVREVDFTKKRLQQEFEDKLEVEQQNKRQLERR--LGDLQADS---- 1418
D + EW+L + F ++ L+Q+ E + E E + + R LG L
Sbjct: 711 DASNSEWQLGKTKV-----FLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKV 765
Query: 1419 -------EESQRALQQLKKKCQRLTAELQDTKLHLEGQQVRNHELEKKQRRFDSELSQAH 1471
+++ RA L+++ L + L GQ R + + + E +
Sbjct: 766 LYCVVIIQKNYRAFL-LRRRFLHLKKAAIVFQKQLRGQIARRVYRQLLAEKREQEEKKKQ 824
Query: 1472 EEAQREKLQREKLQREKDMLLAEAFSLKQQLEEKDMDIAGF--TQKVVSLEAELQDISSQ 1529
EE +++K + E+ +RE++ AE + +++ K ++ +QK L EL+ +
Sbjct: 825 EEEEKKKREEEERERERERREAELRAQQEEETRKQQELEALQKSQKEAELTRELE--KQK 882
Query: 1530 ESKDEASLAKVKKQLRDLEAKVKDQEEELDEQAGTIQMLEQAK----LRLEMEMERMRQT 1585
E+K + +++K++ DL+ + QE L E ++Q L++ + RLE E R Q
Sbjct: 883 ENKQVEEILRLEKEIEDLQRMKEQQELSLTE--ASLQKLQERRDQELRRLEEEACRAAQE 940
Query: 1586 HSKEMESRDEEVEEARQSCQKKL 1608
+ + +E++E ++ ++ L
Sbjct: 941 FLESLNF--DEIDECVRNIERSL 961
Score = 45.8 bits (107), Expect = 4e-04
Identities = 66/277 (23%), Positives = 114/277 (41%), Gaps = 36/277 (12%)
Query: 1733 QLSRLQREKNEIQNRLEEDQEDMNELMKKHKAAVAQASRDLAQINDLQAQLEEANKEKQE 1792
QL +RE+ E + + EE+++ E ++ + +A +L+AQ EE +++QE
Sbjct: 810 QLLAEKREQEEKKKQEEEEKKKREEEERERERERREA--------ELRAQQEEETRKQQE 861
Query: 1793 LQEKLQALQSQVEFLEQSMVDKSLVSRQEAKIRELETRLEFERTQVKRLESLASRLKENM 1852
L E LQ Q + E + ++K ++Q +I LE +E + ++K + L S + ++
Sbjct: 862 L-EALQKSQKEAELTRE--LEKQKENKQVEEILRLEKEIE-DLQRMKEQQEL-SLTEASL 916
Query: 1853 EKLTEERDQRIAAENRE-----------------KEQNKRLQRQLRDTKEEMGELARKEA 1895
+KL E RDQ + E E + ++R L E ELA
Sbjct: 917 QKLQERRDQELRRLEEEACRAAQEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESAC 976
Query: 1896 EASRKKHELEMDLESLEAANQSLQADLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDS 1955
E + + E E ++ +AD AFK D E + S+ S
Sbjct: 977 EEKPNFNFSQPYPE--EEVDEGFEAD-DDAFK---DSPNPSEHGHSDQRTSGIRTSDDSS 1030
Query: 1956 DVDSELEDRVDGVKSWLSKNKGPSKAASDDGSLKSSS 1992
+ D + D V + + D GSL +SS
Sbjct: 1031 EEDPYMNDTVVPTSPSADSTVLLAPSVQDSGSLHNSS 1067
Score = 42.4 bits (98), Expect = 0.005
Identities = 31/100 (31%), Positives = 57/100 (57%), Gaps = 13/100 (13%)
Query: 1541 KKQLRDLEAKVKDQEEELDEQAGTIQMLEQAKLRLEMEMERMRQTHSKEMESRDEEVEEA 1600
++ R L A+ ++QEE+ ++ E+ K R E E ER R+ E+ ++ EE
Sbjct: 805 RRVYRQLLAEKREQEEKKKQEE------EEKKKREEEERERERERREAELRAQQEEETRK 858
Query: 1601 RQ---SCQKKLKQMEV--QLEEEYEDKQ--KVLREKRELE 1633
+Q + QK K+ E+ +LE++ E+KQ ++LR ++E+E
Sbjct: 859 QQELEALQKSQKEAELTRELEKQKENKQVEEILRLEKEIE 898
Score = 41.6 bits (96), Expect = 0.008
Identities = 67/281 (23%), Positives = 123/281 (43%), Gaps = 34/281 (12%)
Query: 1531 SKDEASLAKVKKQLRD-LEAKV-KDQEEELDEQAGTIQ-----MLEQAKLRLEMEMERMR 1583
S E L K K LR+ LE K+ K +EEE+ A I+ L + + R + +
Sbjct: 713 SNSEWQLGKTKVFLRESLEQKLEKRREEEVSHAAMVIRAHVLGFLARKQYRKVLYCVVII 772
Query: 1584 QTHSKE--MESRDEEVEEARQSCQKKLKQMEVQLEEEYEDKQKVLREKRELEGKLATLSD 1641
Q + + + R +++A QK+L+ + +++L EKRE E K +
Sbjct: 773 QKNYRAFLLRRRFLHLKKAAIVFQKQLRGQIAR-----RVYRQLLAEKREQEEKKKQEEE 827
Query: 1642 QVNRRDFESEKRLRKDLKRTKALLADAQLMLDHLKNSAPSKREIAQLKNQLEESEFTCAA 1701
+ +R+ E +R R+ R +A L Q + ++E+ L+ +E+E T
Sbjct: 828 EKKKREEEERERERE---RREAELRAQQ------EEETRKQQELEALQKSQKEAELTREL 878
Query: 1702 AVKARKAMEVEIEDLHLQIDDIAKAK-----TALEEQLSRLQREKNEIQNRLEED----- 1751
+ EI L +I+D+ + K + E L +LQ +++ RLEE+
Sbjct: 879 EKQKENKQVEEILRLEKEIEDLQRMKEQQELSLTEASLQKLQERRDQELRRLEEEACRAA 938
Query: 1752 QEDMNEL-MKKHKAAVAQASRDLAQINDLQAQLEEANKEKQ 1791
QE + L + V R L+ ++ ++L E+ E++
Sbjct: 939 QEFLESLNFDEIDECVRNIERSLSVGSEFSSELAESACEEK 979
Score = 36.2 bits (82), Expect = 0.34
Identities = 21/103 (20%), Positives = 52/103 (50%), Gaps = 12/103 (11%)
Query: 1861 QRIAAENREKEQNKRLQRQLRDTKEEMGELARKEAEASRKKHELEMDLESLEAANQSLQA 1920
+++ AE RE+E+ K+ + + + +EE +E E R++ E E+ + E + +
Sbjct: 809 RQLLAEKREQEEKKKQEEEEKKKREE------EERERERERREAELRAQQEEETRKQQEL 862
Query: 1921 DLKLAFKRIGDLQAAIEDEMESDENEDLINSEGDSDVDSELED 1963
+ ++ +L +E + E+ + E+++ ++ E+ED
Sbjct: 863 EALQKSQKEAELTRELEKQKENKQVEEILR------LEKEIED 899
>gi|189083802 myosin VIIA isoform 2 [Homo sapiens]
Length = 2175
Score = 225 bits (574), Expect = 3e-58
Identities = 267/1053 (25%), Positives = 446/1053 (42%), Gaps = 167/1053 (15%)
Query: 369 EELNLPEGKVRVKLDHDGAILDVDEDDVEKANAP------------SCDRLEDLASLVYL 416
+E ++P G V VKL G + VD++D E +P S +ED+ L L
Sbjct: 18 QEFDVPIGAV-VKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDL 76
Query: 417 NESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYA 476
NE+ +L L RY L++TY G L+ + P ++YS + + + + +M PHI+A
Sbjct: 77 NEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFA 136
Query: 477 VAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALY 536
+A Y M + +DQ I+ G SG+GKT S + ++Q+L A ISG + ++
Sbjct: 137 IADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFL---AAISGQHSWIEQQVLEAT 193
Query: 537 TLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFN 596
+LEAFGN+ TI N N++RF + + + F++ G + A I+ LLEK RV R+ E ++
Sbjct: 194 PILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYH 253
Query: 597 VFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISP 656
VFY +L + +L L ++ N + E + +Q+++ +++AMKVL +
Sbjct: 254 VFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVD-SQEYANIRSAMKVLMFTD 312
Query: 657 DEQKACWFILAAIYHLG---AAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAI 713
E +LAAI HLG T E +A F+ AA LL + +L S +
Sbjct: 313 TENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPS--LATAASLLEVNPPDLMSCL 370
Query: 714 FKHQ--HKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLV 771
+G T+ S Q AL+ + G+Y LF +V +
Sbjct: 371 TSRTLITRGETVSTPLSREQ----------------ALDVRDAFVKGIYGRLFVWIVDKI 414
Query: 772 NRAL-----KSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHER 826
N A+ + ++S S+ ++D GF+N SFE+LC N+ + LQ+ F
Sbjct: 415 NAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVN------SFEQLCINFANEHLQQFFVRH 468
Query: 827 TFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEE 886
F E E Y E+I D L D+ A+D +++ + ++ L++EE
Sbjct: 469 VFKLEQEEYDLESI----DWLHIEFTDNQDALDMIANKPM-----------NIISLIDEE 513
Query: 887 ALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWL 946
+ P ++ T+L +L S + K + + H G +H V Y G+L
Sbjct: 514 SKFPKGTDTTMLHKLNSQH-------KLNANYIPPKNNHETQFGINHFAGIVYYETQGFL 566
Query: 947 NYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMR 1006
++ + +L+ S+ K I +F Q + R
Sbjct: 567 E-KNRDTLHGDIIQLVHSSRNKFIKQIF---------------------QADVAMGAETR 604
Query: 1007 KTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRV 1066
K + +L Q K ++ L+ T+ + FV C P
Sbjct: 605 K---------RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKP----------------- 638
Query: 1067 SSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFD 1126
+E P + D L QLR S +++ +R+ R GYP F EF R+
Sbjct: 639 ---NEFKKP---------MLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYR 686
Query: 1127 VLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDE 1186
VL P + + + D R + + E + +G +++F + LE +RD+
Sbjct: 687 VLLPGVKPAYKQG----DLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDK 742
Query: 1187 QTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKL-FTTVRP 1245
+ + L Q RG+ R +F K K A +Q++ + + K++ +L F ++
Sbjct: 743 AITDRVILLQKVIRGFKDRSNFLKLK---NAATLIQRHWRGHNCRKNYGLMRLGFLRLQA 799
Query: 1246 LIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTG 1305
L + +Q R + I Q +++ +A R R + LT +
Sbjct: 800 LHRSRKLHQQYRLARQRIIQFQARC-RAYLVRKAFR------HRLWAVLTVQAYARGMIA 852
Query: 1306 ESASQLLDAETAERLRAEK----EMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
Q L AE RL AEK E ++L+ + A KK E E + E RL + A
Sbjct: 853 RRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSA-KKAKEEAERKHQE-RLAQLAR---- 906
Query: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE 1394
+DA E LK + A R KK L ++ E
Sbjct: 907 ---EDA--ERELKEKEAARR----KKELLEQME 930
Score = 34.7 bits (78), Expect = 0.98
Identities = 37/111 (33%), Positives = 49/111 (44%), Gaps = 23/111 (20%)
Query: 1825 RELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTK 1884
R L RL E + RLE+ RL E EKL +E + A E E++ +RL
Sbjct: 853 RRLHQRLRAE--YLWRLEAEKMRLAEE-EKLRKEMSAKKAKEEAERKHQERL-------- 901
Query: 1885 EEMGELAR-------KEAEASRKKHEL--EMDLESLEAANQSLQADLKLAF 1926
+LAR KE EA+R+K EL +M+ E N S D F
Sbjct: 902 ---AQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGF 949
Score = 32.0 bits (71), Expect = 6.3
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 7/81 (8%)
Query: 1568 LEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQM-EVQLEEEYEDKQKVL 1626
LE K+RL E E++R KEM ++ + EEA + Q++L Q+ E E ++K+
Sbjct: 867 LEAEKMRLAEE-EKLR----KEMSAKKAK-EEAERKHQERLAQLAREDAERELKEKEAAR 920
Query: 1627 REKRELEGKLATLSDQVNRRD 1647
R+K LE + VN D
Sbjct: 921 RKKELLEQMERARHEPVNHSD 941
Score = 31.6 bits (70), Expect = 8.3
Identities = 37/139 (26%), Positives = 64/139 (46%), Gaps = 15/139 (10%)
Query: 1433 QRLTAE----LQDTKLHLEGQQVRNHEL------EKKQRRFDSELSQ-AHEEAQREKLQR 1481
QRL AE L+ K+ L ++ E+ E+ +R+ L+Q A E+A+RE ++
Sbjct: 857 QRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEK 916
Query: 1482 EKLQREKDMLLAEAFSLKQQLEEKDM--DIAGFTQKVVSLEA-ELQDISSQESKDEASLA 1538
E +R+K++L + + + DM + GF L E Q S E +
Sbjct: 917 EAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRRE 976
Query: 1539 KVKKQLRDLEAKVKDQEEE 1557
V++ L D + D++EE
Sbjct: 977 MVEEDL-DAALPLPDEDEE 994
>gi|189083800 myosin VIIA isoform 3 [Homo sapiens]
Length = 1204
Score = 225 bits (574), Expect = 3e-58
Identities = 267/1053 (25%), Positives = 446/1053 (42%), Gaps = 167/1053 (15%)
Query: 369 EELNLPEGKVRVKLDHDGAILDVDEDDVEKANAP------------SCDRLEDLASLVYL 416
+E ++P G V VKL G + VD++D E +P S +ED+ L L
Sbjct: 18 QEFDVPIGAV-VKLCDSGQVQVVDDEDNEHWISPQNATHIKPMHPTSVHGVEDMIRLGDL 76
Query: 417 NESSVLHTLRQRYGASLLHTYAGPSLLVLGPRGAPAVYSEKVMHMFKGCRREDMAPHIYA 476
NE+ +L L RY L++TY G L+ + P ++YS + + + + +M PHI+A
Sbjct: 77 NEAGILRNLLIRYRDHLIYTYTGSILVAVNPYQLLSIYSPEHIRQYTNKKIGEMPPHIFA 136
Query: 477 VAQTAYRAMLMSRQDQSIILLGSSGSGKTTSCQHLVQYLATIAGISGNKVFSVEKWQALY 536
+A Y M + +DQ I+ G SG+GKT S + ++Q+L A ISG + ++
Sbjct: 137 IADNCYFNMKRNSRDQCCIISGESGAGKTESTKLILQFL---AAISGQHSWIEQQVLEAT 193
Query: 537 TLLEAFGNSPTIINGNATRFSQILSLDFDQAGQVASASIQTMLLEKLRVARRPASEATFN 596
+LEAFGN+ TI N N++RF + + + F++ G + A I+ LLEK RV R+ E ++
Sbjct: 194 PILEAFGNAKTIRNDNSSRFGKYIDIHFNKRGAIEGAKIEQYLLEKSRVCRQALDERNYH 253
Query: 597 VFYYLLACGDGTLRTELHLNHLAENNVFGIVPLAKPEEKQKAAQQFSKLQAAMKVLGISP 656
VFY +L + +L L ++ N + E + +Q+++ +++AMKVL +
Sbjct: 254 VFYCMLEGMSEDQKKKLGLGQASDYNYLAMGNCITCEGRVD-SQEYANIRSAMKVLMFTD 312
Query: 657 DEQKACWFILAAIYHLG---AAGATKEAAEAGRKQFARHEWAQKAAYLLGCSLEELSSAI 713
E +LAAI HLG T E +A F+ AA LL + +L S +
Sbjct: 313 TENWEISKLLAAILHLGNLQYEARTFENLDACEVLFSPS--LATAASLLEVNPPDLMSCL 370
Query: 714 FKHQ--HKGGTLQRSTSFRQGPEESGLGDGTGPKLSALECLEGMAAGLYSELFTLLVSLV 771
+G T+ S Q AL+ + G+Y LF +V +
Sbjct: 371 TSRTLITRGETVSTPLSREQ----------------ALDVRDAFVKGIYGRLFVWIVDKI 414
Query: 772 NRAL-----KSSQHSLCSMMIVDTPGFQNPEQGGSARGASFEELCHNYTQDRLQRLFHER 826
N A+ + ++S S+ ++D GF+N SFE+LC N+ + LQ+ F
Sbjct: 415 NAAIYKPPSQDVKNSRRSIGLLDIFGFENFAVN------SFEQLCINFANEHLQQFFVRH 468
Query: 827 TFVQELERYKEENIELAFDDLEPPTDDSVAAVDQASHQSLVRSLARTDEARGLLWLLEEE 886
F E E Y E+I D L D+ A+D +++ + ++ L++EE
Sbjct: 469 VFKLEQEEYDLESI----DWLHIEFTDNQDALDMIANKPM-----------NIISLIDEE 513
Query: 887 ALVPGASEDTLLERLFSYYGPQEGDKKGQSPLLHSSKPHHFLLGHSHGTNWVEYNVTGWL 946
+ P ++ T+L +L S + K + + H G +H V Y G+L
Sbjct: 514 SKFPKGTDTTMLHKLNSQH-------KLNANYIPPKNNHETQFGINHFAGIVYYETQGFL 566
Query: 947 NYTKQNPATQNAPRLLQDSQKKIISNLFLGRAGSATVLSGSIAGLEGGSQLALRRATSMR 1006
++ + +L+ S+ K I +F Q + R
Sbjct: 567 E-KNRDTLHGDIIQLVHSSRNKFIKQIF---------------------QADVAMGAETR 604
Query: 1007 KTFTTGMAAVKKKSLCIQMKLQVDALIDTIKKSKLHFVHCFLPVAEGWAGEPRSASSRRV 1066
K + +L Q K ++ L+ T+ + FV C P
Sbjct: 605 K---------RSPTLSSQFKRSLELLMRTLGACQPFFVRCIKP----------------- 638
Query: 1067 SSSSELDLPSGDHCEAGLLQLDVPLLRTQLRGSRLLDAMRMYRQGYPDHMVFSEFRRRFD 1126
+E P + D L QLR S +++ +R+ R GYP F EF R+
Sbjct: 639 ---NEFKKP---------MLFDRHLCVRQLRYSGMMETIRIRRAGYPIRYSFVEFVERYR 686
Query: 1127 VLAPHLTKKHGRNYIVVDERRAVEELLECLDLEKSSCCMGLSRVFFRAGTLARLEEQRDE 1186
VL P + + + D R + + E + +G +++F + LE +RD+
Sbjct: 687 VLLPGVKPAYKQG----DLRGTCQRMAEAVLGTHDDWQIGKTKIFLKDHHDMLLEVERDK 742
Query: 1187 QTSRNLTLFQAACRGYLARQHFKKRKIQDLAIRCVQKNIKKNKGVKDWPWWKL-FTTVRP 1245
+ + L Q RG+ R +F K K A +Q++ + + K++ +L F ++
Sbjct: 743 AITDRVILLQKVIRGFKDRSNFLKLK---NAATLIQRHWRGHNCRKNYGLMRLGFLRLQA 799
Query: 1246 LIEVQLSEEQIRNKDEEIQQLRSKLEKAEKERNELRLNSDRLESRISELTSELTDERNTG 1305
L + +Q R + I Q +++ +A R R + LT +
Sbjct: 800 LHRSRKLHQQYRLARQRIIQFQARC-RAYLVRKAFR------HRLWAVLTVQAYARGMIA 852
Query: 1306 ESASQLLDAETAERLRAEK----EMKELQTQYDALKKQMEVMEMEVMEARLIRAAEINGE 1361
Q L AE RL AEK E ++L+ + A KK E E + E RL + A
Sbjct: 853 RRLHQRLRAEYLWRLEAEKMRLAEEEKLRKEMSA-KKAKEEAERKHQE-RLAQLAR---- 906
Query: 1362 VDDDDAGGEWRLKYERAVREVDFTKKRLQQEFE 1394
+DA E LK + A R KK L ++ E
Sbjct: 907 ---EDA--ERELKEKEAARR----KKELLEQME 930
Score = 34.7 bits (78), Expect = 0.98
Identities = 37/111 (33%), Positives = 49/111 (44%), Gaps = 23/111 (20%)
Query: 1825 RELETRLEFERTQVKRLESLASRLKENMEKLTEERDQRIAAENREKEQNKRLQRQLRDTK 1884
R L RL E + RLE+ RL E EKL +E + A E E++ +RL
Sbjct: 853 RRLHQRLRAE--YLWRLEAEKMRLAEE-EKLRKEMSAKKAKEEAERKHQERL-------- 901
Query: 1885 EEMGELAR-------KEAEASRKKHEL--EMDLESLEAANQSLQADLKLAF 1926
+LAR KE EA+R+K EL +M+ E N S D F
Sbjct: 902 ---AQLAREDAERELKEKEAARRKKELLEQMERARHEPVNHSDMVDKMFGF 949
Score = 32.0 bits (71), Expect = 6.3
Identities = 27/81 (33%), Positives = 42/81 (51%), Gaps = 7/81 (8%)
Query: 1568 LEQAKLRLEMEMERMRQTHSKEMESRDEEVEEARQSCQKKLKQM-EVQLEEEYEDKQKVL 1626
LE K+RL E E++R KEM ++ + EEA + Q++L Q+ E E ++K+
Sbjct: 867 LEAEKMRLAEE-EKLR----KEMSAKKAK-EEAERKHQERLAQLAREDAERELKEKEAAR 920
Query: 1627 REKRELEGKLATLSDQVNRRD 1647
R+K LE + VN D
Sbjct: 921 RKKELLEQMERARHEPVNHSD 941
Score = 31.6 bits (70), Expect = 8.3
Identities = 37/139 (26%), Positives = 64/139 (46%), Gaps = 15/139 (10%)
Query: 1433 QRLTAE----LQDTKLHLEGQQVRNHEL------EKKQRRFDSELSQ-AHEEAQREKLQR 1481
QRL AE L+ K+ L ++ E+ E+ +R+ L+Q A E+A+RE ++
Sbjct: 857 QRLRAEYLWRLEAEKMRLAEEEKLRKEMSAKKAKEEAERKHQERLAQLAREDAERELKEK 916
Query: 1482 EKLQREKDMLLAEAFSLKQQLEEKDM--DIAGFTQKVVSLEA-ELQDISSQESKDEASLA 1538
E +R+K++L + + + DM + GF L E Q S E +
Sbjct: 917 EAARRKKELLEQMERARHEPVNHSDMVDKMFGFLGTSGGLPGQEGQAPSGFEDLERGRRE 976
Query: 1539 KVKKQLRDLEAKVKDQEEE 1557
V++ L D + D++EE
Sbjct: 977 MVEEDL-DAALPLPDEDEE 994
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.313 0.128 0.352
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 73,388,484
Number of Sequences: 37866
Number of extensions: 3530450
Number of successful extensions: 55306
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 855
Number of HSP's successfully gapped in prelim test: 1468
Number of HSP's that attempted gapping in prelim test: 16400
Number of HSP's gapped (non-prelim): 15156
length of query: 2039
length of database: 18,247,518
effective HSP length: 118
effective length of query: 1921
effective length of database: 13,779,330
effective search space: 26470092930
effective search space used: 26470092930
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 70 (31.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.