Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Search of human proteins with 41352705
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41352705 kinesin family member 3C [Homo sapiens]
(793 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41352705 kinesin family member 3C [Homo sapiens] 1561 0.0
gi|4758646 kinesin family member 3B [Homo sapiens] 907 0.0
gi|46852174 kinesin family member 3A [Homo sapiens] 567 e-161
gi|170784809 kinesin family member 17 isoform b [Homo sapiens] 435 e-122
gi|170784807 kinesin family member 17 isoform a [Homo sapiens] 435 e-122
gi|13699824 kinesin family member 11 [Homo sapiens] 306 5e-83
gi|9910266 kinesin family member 15 [Homo sapiens] 284 2e-76
gi|40254834 kinesin family member 1C [Homo sapiens] 275 2e-73
gi|30794488 kinesin family member 27 [Homo sapiens] 268 2e-71
gi|150010604 kinesin family member 4B [Homo sapiens] 267 3e-71
gi|116686122 kinesin family member 4 [Homo sapiens] 266 4e-71
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 264 2e-70
gi|46852172 kinesin family member 13B [Homo sapiens] 262 8e-70
gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens] 260 4e-69
gi|41393563 kinesin family member 1B isoform b [Homo sapiens] 260 4e-69
gi|19924175 axonal transport of synaptic vesicles [Homo sapiens] 259 7e-69
gi|203096856 kinesin family member 7 [Homo sapiens] 254 3e-67
gi|157738629 kinesin family member 13A isoform d [Homo sapiens] 247 3e-65
gi|157738627 kinesin family member 13A isoform c [Homo sapiens] 247 3e-65
gi|157738625 kinesin family member 13A isoform b [Homo sapiens] 247 3e-65
gi|157738621 kinesin family member 13A isoform a [Homo sapiens] 247 3e-65
gi|45446749 kinesin family member 5A [Homo sapiens] 244 3e-64
gi|71061468 centromere protein E [Homo sapiens] 243 4e-64
gi|38569484 kinesin family member 21A [Homo sapiens] 243 4e-64
gi|7661878 kinesin family member 14 [Homo sapiens] 243 5e-64
gi|4758648 kinesin family member 5B [Homo sapiens] 241 2e-63
gi|148612831 kinesin family member 18A [Homo sapiens] 239 1e-62
gi|83716024 kinesin family member 21B [Homo sapiens] 238 1e-62
gi|4758650 kinesin family member 5C [Homo sapiens] 238 2e-62
gi|156616271 kinesin family member 19 [Homo sapiens] 234 3e-61
>gi|41352705 kinesin family member 3C [Homo sapiens]
Length = 793
Score = 1561 bits (4041), Expect = 0.0
Identities = 793/793 (100%), Positives = 793/793 (100%)
Query: 1 MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTF 60
MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTF
Sbjct: 1 MASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTF 60
Query: 61 DAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVI 120
DAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVI
Sbjct: 61 DAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVI 120
Query: 121 PNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDL 180
PNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDL
Sbjct: 121 PNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDL 180
Query: 181 SSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVG 240
SSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVG
Sbjct: 181 SSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVG 240
Query: 241 KLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSAL 300
KLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSAL
Sbjct: 241 KLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSAL 300
Query: 301 GNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFAN 360
GNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFAN
Sbjct: 301 GNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFAN 360
Query: 361 RAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPG 420
RAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPG
Sbjct: 361 RAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPG 420
Query: 421 YPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRS 480
YPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRS
Sbjct: 421 YPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRS 480
Query: 481 LVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLE 540
LVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLE
Sbjct: 481 LVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLE 540
Query: 541 LKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKA 600
LKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKA
Sbjct: 541 LKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKA 600
Query: 601 EIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWK 660
EIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWK
Sbjct: 601 EIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWK 660
Query: 661 FQPLVPAGVSSSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAENIMFLELDVSPPA 720
FQPLVPAGVSSSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAENIMFLELDVSPPA
Sbjct: 661 FQPLVPAGVSSSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAENIMFLELDVSPPA 720
Query: 721 VFEMEFSHDQEQDPRALHMERLMRLDSFLERPSTSKVRKSRSWCQSPQRPPPSTTHASLA 780
VFEMEFSHDQEQDPRALHMERLMRLDSFLERPSTSKVRKSRSWCQSPQRPPPSTTHASLA
Sbjct: 721 VFEMEFSHDQEQDPRALHMERLMRLDSFLERPSTSKVRKSRSWCQSPQRPPPSTTHASLA 780
Query: 781 SASLRPATVADHE 793
SASLRPATVADHE
Sbjct: 781 SASLRPATVADHE 793
>gi|4758646 kinesin family member 3B [Homo sapiens]
Length = 747
Score = 907 bits (2344), Expect = 0.0
Identities = 476/714 (66%), Positives = 574/714 (80%), Gaps = 48/714 (6%)
Query: 3 SKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDA 62
SK K+SE+++VV RCRP++ KE+AA +++++ +DVKLGQV+++NP+ E+PKTFTFDA
Sbjct: 2 SKLKSSESVRVVVRCRPMNGKEKAASYDKVVDVDVKLGQVSVKNPKGTAHEMPKTFTFDA 61
Query: 63 VYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPN 122
VYD ++KQ +LYDET RPL+DSVLQGFNGT+FAYGQTGTGKTYTM+G +PE RGVIPN
Sbjct: 62 VYDWNAKQFELYDETFRPLVDSVLQGFNGTIFAYGQTGTGKTYTMEGIRGDPEKRGVIPN 121
Query: 123 AFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSS 182
+F+HIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSK+ KRLELKE P+TGVY+KDLSS
Sbjct: 122 SFDHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKDQTKRLELKERPDTGVYVKDLSS 181
Query: 183 FVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKL 242
FVTK+VKEIEHVMN+GNQ R+VG+T+MNE SSRSHAIF+IT+ECSE G DG++HIRVGKL
Sbjct: 182 FVTKSVKEIEHVMNVGNQNRSVGATNMNEHSSRSHAIFVITIECSEVGLDGENHIRVGKL 241
Query: 243 NLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGN 302
NLVDLAGSERQ K GA GER KEA+KINLSLSALGN
Sbjct: 242 NLVDLAGSERQAKT------------------------GAQGERLKEATKINLSLSALGN 277
Query: 303 VIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRA 362
VI+AL +STHIPYRDSKLTRLLQDSLGGNAKT+MVA +GPAS++ +E+L+TLR+ANRA
Sbjct: 278 VISALVDGKSTHIPYRDSKLTRLLQDSLGGNAKTVMVANVGPASYNVEETLTTLRYANRA 337
Query: 363 KNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYP 422
KNIKNKPRVNEDPKD LLREFQEEIARLKAQLEKR +G+R RR+ RR+ S G
Sbjct: 338 KNIKNKPRVNEDPKDALLREFQEEIARLKAQLEKRS-IGRRKRRE-KRREGGGSGGGGEE 395
Query: 423 EGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRSLV 482
E E EEE D+ ++Y +EQ+E+LE EK AI +D SLV
Sbjct: 396 EEE--EGEEGEEEGDDK------------------DDYWREQQEKLEIEKRAIVEDHSLV 435
Query: 483 SEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELK 542
+EEK +LL+EKEK +EDLRRE+ A E+L AK KAMESKLL+GG+NI+DHTNEQQK+LE K
Sbjct: 436 AEEKMRLLKEKEKKMEDLRREKDAAEMLGAKIKAMESKLLVGGKNIVDHTNEQQKILEQK 495
Query: 543 RQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEI 602
RQEIAEQKRRERE+QQ+M RDEET+EL+ TY+SLQQEV++KTKKLKKL++KLQAVKAEI
Sbjct: 496 RQEIAEQKRREREIQQQMESRDEETLELKETYSSLQQEVDIKTKKLKKLFSKLQAVKAEI 555
Query: 603 QDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWKFQ 662
D +E+I+ RQ+LE+ QNE TRELKLK+LIIENFIP EEK+KIMNR F D EE+ WK
Sbjct: 556 HDLQEEHIKERQELEQTQNELTRELKLKHLIIENFIPLEEKSKIMNRAFFDEEEDHWKLH 615
Query: 663 PLVPAGVSSSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAENIMFLELDV 716
P+ + + QM KRP SAVGYKRP+SQ+AR++M + RYRAENI+ LELD+
Sbjct: 616 PI--TRLENQQMMKRPVSAVGYKRPLSQHARMSMMIRPEARYRAENIVLLELDM 667
>gi|46852174 kinesin family member 3A [Homo sapiens]
Length = 699
Score = 567 bits (1461), Expect = e-161
Identities = 305/687 (44%), Positives = 448/687 (65%), Gaps = 50/687 (7%)
Query: 2 ASKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFD 61
+ K ++ + +KVV RCRPL+ +E++ ++Q +++D G +T+ ++ E PKTFTFD
Sbjct: 6 SEKPESCDNVKVVVRCRPLNEREKSMCYKQAVSVDEMRGTITVHKTDSS-NEPPKTFTFD 64
Query: 62 AVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIP 121
V+ SKQ D+Y+ T RP+IDSVL+G+NGT+FAYGQTGTGKT+TM+G PELRG+IP
Sbjct: 65 TVFGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTMEGVRAIPELRGIIP 124
Query: 122 NAFEHIFTHISRSQNQ-QYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDL 180
N+F HIF HI++++ ++LVR SYLEIY EE+RDLL K+ +RLE+KE P+ GVYIKDL
Sbjct: 125 NSFAHIFGHIAKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQTQRLEVKERPDVGVYIKDL 184
Query: 181 SSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVG 240
S++V N +++ +M LG++ R+VG+T+MNE SSRSHAIF IT+ECSE+G DG H+R+G
Sbjct: 185 SAYVVNNADDMDRIMTLGHKNRSVGATNMNEHSSRSHAIFTITIECSEKGIDGNMHVRMG 244
Query: 241 KLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSAL 300
KL+LVDLAGSERQ K G A G+R KEA+KINLSLS L
Sbjct: 245 KLHLVDLAGSERQAKTG------------------------ATGQRLKEATKINLSLSTL 280
Query: 301 GNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFAN 360
GNVI+AL +STH+PYR+SKLTRLLQDSLGGN+KT+M A +GPA ++YDE++STLR+AN
Sbjct: 281 GNVISALVDGKSTHVPYRNSKLTRLLQDSLGGNSKTMMCANIGPADYNYDETISTLRYAN 340
Query: 361 RAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPG 420
RAKNIKNK R+NEDPKD LLR+FQ+EI LK +LE+ + + S G
Sbjct: 341 RAKNIKNKARINEDPKDALLRQFQKEIEELKKKLEE-------------GEEISGSDISG 387
Query: 421 YPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRS 480
E E V E+ + +K + + E + +++EE+ A++
Sbjct: 388 SEEDDDEEGEVGEDGEKRKKRR---------GKKKVSPDKMIEMQAKIDEERKALETKLD 438
Query: 481 LVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLE 540
+ EE+ K E EK +DL + QQ + L K A+E K+++GG +++ EQ+K+LE
Sbjct: 439 MEEEERNKARAELEKREKDLLKAQQEHQSLLEKLSALEKKVIVGGVDLLAKAEEQEKLLE 498
Query: 541 LKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKA 600
E+ E+++R ++++E+ +++E +++ YTSLQ+E + KTKKLKK++ L A K+
Sbjct: 499 ESNMELEERRKRAEQLRRELEEKEQERLDIEEKYTSLQEEAQGKTKKLKKVWTMLMAAKS 558
Query: 601 EIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWK 660
E+ D E+ R + L E + +REL+L+ LII+NFIP + + I N + + + +W+
Sbjct: 559 EMADLQQEHQREIEGLLENIRQLSRELRLQMLIIDNFIPRDYQEMIENYVHWNEDIGEWQ 618
Query: 661 FQPLVPAGVSSSQMKKRPTSAVGYKRP 687
+ + G ++ K+ P K P
Sbjct: 619 LKCVAYTG--NNMRKQTPVPDKKEKDP 643
>gi|170784809 kinesin family member 17 isoform b [Homo sapiens]
Length = 1028
Score = 435 bits (1118), Expect = e-122
Identities = 244/517 (47%), Positives = 326/517 (63%), Gaps = 53/517 (10%)
Query: 7 ASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDA 66
ASEA+KVV RCRP++++E + ++T+D Q ++NP AA E PK FTFD Y
Sbjct: 2 ASEAVKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAAD-EPPKQFTFDGAYHV 60
Query: 67 SSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEH 126
+Y+E PL++ V +G+NGT+FAYGQTG+GK++TMQG P RG+IP AFEH
Sbjct: 61 DHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEH 120
Query: 127 IFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVTK 186
+F + ++N ++LVRASYLEIY E++RDLL + ++LELKE+PE GVY+K LS
Sbjct: 121 VFESVQCAENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVYVKGLSMHTVH 180
Query: 187 NVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKLNLVD 246
+V + EH+M G + R+VG T MN+ SSRSH+IF I++E S G+DH+R GKLNLVD
Sbjct: 181 SVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVD 240
Query: 247 LAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGNVIAA 306
LAGSERQ+K GA GER KEA+KINLSLSALGNVI+A
Sbjct: 241 LAGSERQSKT------------------------GATGERLKEATKINLSLSALGNVISA 276
Query: 307 LAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIK 366
L R H+PYRDSKLTRLLQDSLGGN KT+MVA L PA ++YDE+LSTLR+ANRAKNI+
Sbjct: 277 LVDGRCKHVPYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIR 336
Query: 367 NKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPV 426
NKPR+NEDPKD LLRE+QEEI +LKA L ++ P S+ + V P E +
Sbjct: 337 NKPRINEDPKDALLREYQEEIKKLKAILTQQ----MSPSSLSALLSRQVPPDPVQVEEKL 392
Query: 427 IEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKA---AIQDDRSLVS 483
+ PQP+++ +E + +E +ERL KA A Q+ R+ +
Sbjct: 393 L-----------------PQPVIQHDVEAEKQLIREEYEERLARLKADYKAEQESRARLE 435
Query: 484 EEKQKLLEEKEKML----EDLRREQQATELLAAKYKA 516
E+ + + L E+LR+E +A + YKA
Sbjct: 436 EDITAMRNSYDVRLSTLEENLRKETEAVLQVGVLYKA 472
Score = 50.1 bits (118), Expect = 8e-06
Identities = 51/214 (23%), Positives = 90/214 (42%), Gaps = 25/214 (11%)
Query: 512 AKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELR 571
A+ + +E ++ +GG N+ K +R+ A+++R++ + D L
Sbjct: 743 ARLQLLEQQV-VGGEQAK---NKDLKEKHKRRKRYADERRKQLVAALQNSDEDSGDWVLL 798
Query: 572 GTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTRELKLKY 631
Y S+Q+EV K+K L+K+ KL+A + EI+D E+ + D Q R+ L
Sbjct: 799 NVYDSIQEEVRAKSKLLEKMQRKLRAAEVEIKDLQSEFQLEKIDYLATIRRQERDSMLLQ 858
Query: 632 LIIENFIPPEEKN-------KIMNRLFLDCEEEQWKFQ---------PLVPAGVSSSQMK 675
++E P ++ KI+ D + WK P+V G + +
Sbjct: 859 QLLEQVQPLIRRDCNYSNLEKILRESCWDEDNGFWKIPHPVITKTSLPVVSTGPQNKPAR 918
Query: 676 KRPTSAVGYKRPISQYARVAMAMGSHPRYRAENI 709
K TSA P + R + + R +ENI
Sbjct: 919 K--TSAADNGEPNMEDDRYRLMLS---RSNSENI 947
>gi|170784807 kinesin family member 17 isoform a [Homo sapiens]
Length = 1029
Score = 435 bits (1118), Expect = e-122
Identities = 244/517 (47%), Positives = 326/517 (63%), Gaps = 53/517 (10%)
Query: 7 ASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDA 66
ASEA+KVV RCRP++++E + ++T+D Q ++NP AA E PK FTFD Y
Sbjct: 2 ASEAVKVVVRCRPMNQRERELRCQPVVTVDCARAQCCIQNPGAAD-EPPKQFTFDGAYHV 60
Query: 67 SSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEH 126
+Y+E PL++ V +G+NGT+FAYGQTG+GK++TMQG P RG+IP AFEH
Sbjct: 61 DHVTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPSQRGIIPRAFEH 120
Query: 127 IFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVTK 186
+F + ++N ++LVRASYLEIY E++RDLL + ++LELKE+PE GVY+K LS
Sbjct: 121 VFESVQCAENTKFLVRASYLEIYNEDVRDLLGADTKQKLELKEHPEKGVYVKGLSMHTVH 180
Query: 187 NVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKLNLVD 246
+V + EH+M G + R+VG T MN+ SSRSH+IF I++E S G+DH+R GKLNLVD
Sbjct: 181 SVAQCEHIMETGWKNRSVGYTLMNKDSSRSHSIFTISIEMSAVDERGKDHLRAGKLNLVD 240
Query: 247 LAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGNVIAA 306
LAGSERQ+K GA GER KEA+KINLSLSALGNVI+A
Sbjct: 241 LAGSERQSKT------------------------GATGERLKEATKINLSLSALGNVISA 276
Query: 307 LAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIK 366
L R H+PYRDSKLTRLLQDSLGGN KT+MVA L PA ++YDE+LSTLR+ANRAKNI+
Sbjct: 277 LVDGRCKHVPYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYDETLSTLRYANRAKNIR 336
Query: 367 NKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPV 426
NKPR+NEDPKD LLRE+QEEI +LKA L ++ P S+ + V P E +
Sbjct: 337 NKPRINEDPKDALLREYQEEIKKLKAILTQQ----MSPSSLSALLSRQVPPDPVQVEEKL 392
Query: 427 IEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKA---AIQDDRSLVS 483
+ PQP+++ +E + +E +ERL KA A Q+ R+ +
Sbjct: 393 L-----------------PQPVIQHDVEAEKQLIREEYEERLARLKADYKAEQESRARLE 435
Query: 484 EEKQKLLEEKEKML----EDLRREQQATELLAAKYKA 516
E+ + + L E+LR+E +A + YKA
Sbjct: 436 EDITAMRNSYDVRLSTLEENLRKETEAVLQVGVLYKA 472
Score = 52.8 bits (125), Expect = 1e-06
Identities = 53/213 (24%), Positives = 92/213 (43%), Gaps = 22/213 (10%)
Query: 512 AKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELR 571
A+ + +E ++ +GG N+ K +R+ A+++R++ + D L
Sbjct: 743 ARLQLLEQQV-VGGEQAK---NKDLKEKHKRRKRYADERRKQLVAALQNSDEDSGDWVLL 798
Query: 572 GTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTRELKLKY 631
Y S+Q+EV K+K L+K+ KL+A + EI+D E+ + D Q R+ L
Sbjct: 799 NVYDSIQEEVRAKSKLLEKMQRKLRAAEVEIKDLQSEFQLEKIDYLATIRRQERDSMLLQ 858
Query: 632 LIIENFIPPEEKN-------KIMNRLFLDCEEEQWKF-QPLV-----PAGVSSSQMKK-- 676
++E P ++ KI+ D + WK P++ P VS+ K
Sbjct: 859 QLLEQVQPLIRRDCNYSNLEKILRESCWDEDNGFWKIPHPVITKTSLPVAVSTGPQNKPA 918
Query: 677 RPTSAVGYKRPISQYARVAMAMGSHPRYRAENI 709
R TSA P + R + + R +ENI
Sbjct: 919 RKTSAADNGEPNMEDDRYRLMLS---RSNSENI 948
>gi|13699824 kinesin family member 11 [Homo sapiens]
Length = 1056
Score = 306 bits (784), Expect = 5e-83
Identities = 218/651 (33%), Positives = 328/651 (50%), Gaps = 77/651 (11%)
Query: 4 KTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAV 63
K + + ++VV RCRP + E A I+ D +V++R A KT+TFD V
Sbjct: 12 KEEKGKNIQVVVRCRPFNLAERKASAHSIVECDPVRKEVSVRTGGLADKSSRKTYTFDMV 71
Query: 64 YDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQG--------TWVEPE 115
+ AS+KQ D+Y V P++D V+ G+N T+FAYGQTGTGKT+TM+G TW E
Sbjct: 72 FGASTKQIDVYRSVVCPILDEVIMGYNCTIFAYGQTGTGKTFTMEGERSPNEEYTWEEDP 131
Query: 116 LRGVIPNAFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLL--SKEPGKRLELKENP-- 171
L G+IP IF ++ ++ V+ S LEIY EE+ DLL S + +RL++ ++P
Sbjct: 132 LAGIIPRTLHQIFEKLT-DNGTEFSVKVSLLEIYNEELFDLLNPSSDVSERLQMFDDPRN 190
Query: 172 ETGVYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGS 231
+ GV IK L N E+ ++ G R +T MN SSRSH++F +T+ E
Sbjct: 191 KRGVIIKGLEEITVHNKDEVYQILEKGAAKRTTAATLMNAYSSRSHSVFSVTIHMKETTI 250
Query: 232 DGQDHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEAS 291
DG++ +++GKLNLVDLAGSE ++ GA +R +EA
Sbjct: 251 DGEELVKIGKLNLVDLAGSENIGRS------------------------GAVDKRAREAG 286
Query: 292 KINLSLSALGNVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDE 351
IN SL LG VI AL R+ H+PYR+SKLTR+LQDSLGG +T ++AT+ PAS + +E
Sbjct: 287 NINQSLLTLGRVITALV-ERTPHVPYRESKLTRILQDSLGGRTRTSIIATISPASLNLEE 345
Query: 352 SLSTLRFANRAKNIKNKPRVNED-PKDTLLREFQEEIARLKAQL----EKRGMLGKRPRR 406
+LSTL +A+RAKNI NKP VN+ K L++E+ EEI RLK L EK G+
Sbjct: 346 TLSTLEYAHRAKNILNKPEVNQKLTKKALIKEYTEEIERLKRDLAAAREKNGVYISEENF 405
Query: 407 KSSRRKKAVSAPPGYPEGPVIEAWVAEEED---------DNNNNHRPPQPILESALE--K 455
+ K V +IE A EE+ DN N + L++ + +
Sbjct: 406 RVMSGKLTVQEEQIV---ELIEKIGAVEEELNRVTELFMDNKNELDQCKSDLQNKTQELE 462
Query: 456 NMENYLQEQKERLEEEK---AAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAA 512
+ +LQE K +L +E+ +A++ + + KLL E+ +D+ + A
Sbjct: 463 TTQKHLQETKLQLVKEEYITSALESTEEKLHDAASKLLNTVEETTKDVSGLHSKLDRKKA 522
Query: 513 KYKAMESKLLIGGRN-----------IMDHTNEQQKMLELKRQEIAEQKRREREMQQEMM 561
+ I G+N I D +++Q+ MLE+ + + +
Sbjct: 523 VDQHNAEAQDIFGKNLNSLFNNMEELIKDGSSKQKAMLEVHKTLFGNL------LSSSVS 576
Query: 562 LRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRV 612
D T G+ TS+ + V ++ + K Q++ AE + E I V
Sbjct: 577 ALDTITTVALGSLTSIPENVSTHVSQIFNMILKEQSLAAESKTVLQELINV 627
>gi|9910266 kinesin family member 15 [Homo sapiens]
Length = 1388
Score = 284 bits (727), Expect = 2e-76
Identities = 238/747 (31%), Positives = 367/747 (49%), Gaps = 76/747 (10%)
Query: 9 EALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLR---NPRAAPGELPKTFTFDAVYD 65
+A+KV R RP + + +A EQ L + V L +LR NP PKTFTFD V D
Sbjct: 25 DAIKVFVRIRPPAERSGSADGEQNLCLSV-LSSTSLRLHSNPE------PKTFTFDHVAD 77
Query: 66 ASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPE----LRGVIP 121
+ Q ++ + +++S + G+NGT+FAYGQTG+GKT+TM G LRGVIP
Sbjct: 78 VDTTQESVFATVAKSIVESCMSGYNGTIFAYGQTGSGKTFTMMGPSESDNFSHNLRGVIP 137
Query: 122 NAFEHIFTHISRSQNQ-----QYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVY 176
+FE++F+ I R + + +L + S++EIY E+I DLL L L+E+ + GV+
Sbjct: 138 RSFEYLFSLIDREKEKAGAGKSFLCKCSFIEIYNEQIYDLLDSASAG-LYLREHIKKGVF 196
Query: 177 IKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDH 236
+ V + E V++ G + R V ST MN SSRSHA+F IT+E E+ ++ +
Sbjct: 197 VVGAVEQVVTSAAEAYQVLSGGWRNRRVASTSMNRESSRSHAVFTITIESMEKSNEIVN- 255
Query: 237 IRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLS 296
IR LNLVDLAGSERQ A G R KEA IN S
Sbjct: 256 IRTSLLNLVDLAGSERQKDTH------------------------AEGMRLKEAGNINRS 291
Query: 297 LSALGNVIAALA--GN-RSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESL 353
LS LG VI AL GN + H+ YRDSKLT LL+DSLGGNAKT ++A + P S + E+L
Sbjct: 292 LSCLGQVITALVDVGNGKQRHVCYRDSKLTFLLRDSLGGNAKTAIIANVHPGSRCFGETL 351
Query: 354 STLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKK 413
STL FA RAK IKNK VNED + + + Q E+ RLK QL + P +R KK
Sbjct: 352 STLNFAQRAKLIKNKAVVNEDTQGN-VSQLQAEVKRLKEQLAELASGQTPPESFLTRDKK 410
Query: 414 AVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKA 473
+ + E + + + E + + + + L+K E ++Q K ++ +
Sbjct: 411 KTNYMEYFQEAML---FFKKSEQEKKSLIEKVTQLEDLTLKK--EKFIQSNKMIVKFRED 465
Query: 474 AIQDDRSLVSEEKQKLL-EEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHT 532
I L E + L EE++++L +LR E Q + +E + + +H+
Sbjct: 466 QIIRLEKLHKESRGGFLPEEQDRLLSELRNEIQTLR------EQIEHHPRVAKYAMENHS 519
Query: 533 NEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETM-ELRGTYTS--LQQEVEVKTKKLK 589
+ E +R + E +R +EM + + + E+ E+ G S QQ K +K
Sbjct: 520 LRE----ENRRLRLLEPVKRAQEMDAQTIAKLEKAFSEISGMEKSDKNQQGFSPKAQKEP 575
Query: 590 KLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNR 649
L+A + +KA++ E +Q+ EE + E TR+ +L+ +E+ + +K +
Sbjct: 576 CLFANTEKLKAQLLQIQTELNNSKQEYEEFK-ELTRKRQLE---LESELQSLQKANLNLE 631
Query: 650 LFLDCEEEQWKFQPLVPAGVSSSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAENI 709
L+ + + + + + +K T Y+ +++ MGS +N
Sbjct: 632 NLLEATKACKRQEVSQLNKIHAETLKIITTPTKAYQLHSRPVPKLSPEMGSFGSLYTQNS 691
Query: 710 MFLELDV----SPPAVFEMEFSHDQEQ 732
L+ D+ PP + E F E+
Sbjct: 692 SILDNDILNEPVPPEMNEQAFEAISEE 718
Score = 40.8 bits (94), Expect = 0.005
Identities = 32/167 (19%), Positives = 83/167 (49%), Gaps = 10/167 (5%)
Query: 461 LQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQA--------TELLAA 512
L+ + E+L E KA +QD + E + +++ + L++ ++E + ELL A
Sbjct: 849 LRLENEKLLESKACLQDSYDNLQEIMKFEIDQLSRNLQNFKKENETLKSDLNNLMELLEA 908
Query: 513 KYKAMESKLLIGGRNIMDHTNEQ-QKMLELKRQEIAEQKRREREMQQEMMLRDEETMELR 571
+ K +KL + ++++++ K+LE RQE ++ + + ++ +E +
Sbjct: 909 E-KERNNKLSLQFEEDKENSSKEILKVLEAVRQEKQKETAKCEQQMAKVQKLEESLLATE 967
Query: 572 GTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEE 618
+SL++ + K + L ++Q ++ + ++ + ++Q+L++
Sbjct: 968 KVISSLEKSRDSDKKVVADLMNQIQELRTSVCEKTETIDTLKQELKD 1014
Score = 37.0 bits (84), Expect = 0.072
Identities = 55/291 (18%), Positives = 119/291 (40%), Gaps = 30/291 (10%)
Query: 348 SYDESLSTLRFA--NRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPR 405
SYD ++F ++N++N + NE TL + + L+A+ E+ L +
Sbjct: 866 SYDNLQEIMKFEIDQLSRNLQNFKKENE----TLKSDLNNLMELLEAEKERNNKLSLQFE 921
Query: 406 RKSSRRKKAVSAPPGYPEGPVIEAWVAEEEDDN---NNNHRPPQPILESALEKNMENYLQ 462
K + V+EA E++ + Q + ES L E +
Sbjct: 922 EDKENSSKEILK--------VLEAVRQEKQKETAKCEQQMAKVQKLEESLLAT--EKVIS 971
Query: 463 EQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAM----- 517
++ + +K + D + + E + + E+ E ++ L++E + + KY +
Sbjct: 972 SLEKSRDSDKKVVADLMNQIQELRTSVCEKTET-IDTLKQELKD---INCKYNSALVDRE 1027
Query: 518 ESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRRE--REMQQEMMLRDEETMELRGTYT 575
ES++LI + + ++ L + ++I E +++ + E + + G
Sbjct: 1028 ESRVLIKKQEVDILDLKETLRLRILSEDIERDMLCEDLAHATEQLNMLTEASKKHSGLLQ 1087
Query: 576 SLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTRE 626
S Q+E+ K +++L KL K E++ + +EY + LE + +
Sbjct: 1088 SAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAED 1138
Score = 36.6 bits (83), Expect = 0.094
Identities = 25/105 (23%), Positives = 54/105 (51%), Gaps = 5/105 (4%)
Query: 467 RLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYK--AMESKLLIG 524
R+ +E Q S +EK++L + E+M E+ R Q E+L + + A E+ L+G
Sbjct: 1286 RMTDEVERTQTLESKAFQEKEQLRSKLEEMYEERERTSQEMEMLRKQVECLAEENGKLVG 1345
Query: 525 GRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETME 569
+N+ + Q ++ LK++ + + E+ + + L++++ E
Sbjct: 1346 HQNL---HQKIQYVVRLKKENVRLAEETEKLRAENVFLKEKKRSE 1387
Score = 35.8 bits (81), Expect = 0.16
Identities = 43/214 (20%), Positives = 99/214 (46%), Gaps = 37/214 (17%)
Query: 450 ESALEKNMENYLQEQKERLEEEK---------------AAIQDDRSLVSEEK-----QKL 489
+ AL + +++ L ++KE +E++K +A +D +S + KL
Sbjct: 1096 KEALIQELQHKLNQKKEEVEQKKNEYNFKMRQLEHVMDSAAEDPQSPKTPPHFQTHLAKL 1155
Query: 490 LEEKEKMLEDLRREQQATELLAAKY----KAMESKLLIGGRNIMDHTN---EQQKMLE-- 540
LE +E+ +ED R + + E L K + +++L + + N E Q+++E
Sbjct: 1156 LETQEQEIEDGRASKTSLEHLVTKLNEDREVKNAEILRMKEQLREMENLRLESQQLIEKN 1215
Query: 541 -LKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTK---KLKKLYAKLQ 596
L + ++ + KR++ Q + +L+ +E K+K ++ K+ A L+
Sbjct: 1216 WLLQGQLDDIKRQKENSDQ----NHPDNQQLKNEQEESIKERLAKSKIVEEMLKMKADLE 1271
Query: 597 AVKAEIQDQHDEYIRVRQDLEEAQNEQTRELKLK 630
V++ + ++ E +R+ ++E Q +++ + K
Sbjct: 1272 EVQSALYNKEMECLRMTDEVERTQTLESKAFQEK 1305
Score = 35.0 bits (79), Expect = 0.27
Identities = 43/211 (20%), Positives = 91/211 (43%), Gaps = 27/211 (12%)
Query: 442 HRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLR 501
H Q + + K LQ +E L +++A IQ+ + ++++K+++ ++K + +R
Sbjct: 1067 HATEQLNMLTEASKKHSGLLQSAQEELTKKEALIQELQHKLNQKKEEVEQKKNEYNFKMR 1126
Query: 502 REQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQK----------- 550
+ + + A ++ ++ + H K+LE + QEI + +
Sbjct: 1127 QLEHVMDSAAEDPQSPKTP-----PHFQTHL---AKLLETQEQEIEDGRASKTSLEHLVT 1178
Query: 551 --RREREMQQEMMLR-DEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHD 607
+RE++ +LR E+ E+ QQ +E K L +L +K + ++ D
Sbjct: 1179 KLNEDREVKNAEILRMKEQLREMENLRLESQQLIE----KNWLLQGQLDDIKRQ-KENSD 1233
Query: 608 EYIRVRQDLEEAQNEQTRELKLKYLIIENFI 638
+ Q L+ Q E +E K I+E +
Sbjct: 1234 QNHPDNQQLKNEQEESIKERLAKSKIVEEML 1264
Score = 33.9 bits (76), Expect = 0.61
Identities = 43/179 (24%), Positives = 78/179 (43%), Gaps = 17/179 (9%)
Query: 450 ESALEKN--MENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEE--KEKMLED-LRREQ 504
+ +EKN ++ L + K + E D++ L +E+++ + E K K++E+ L+ +
Sbjct: 1209 QQLIEKNWLLQGQLDDIKRQKENSDQNHPDNQQLKNEQEESIKERLAKSKIVEEMLKMKA 1268
Query: 505 QATELLAAKY-KAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLR 563
E+ +A Y K ME M E+ + LE K + EQ R + E E R
Sbjct: 1269 DLEEVQSALYNKEMECLR-------MTDEVERTQTLESKAFQEKEQLRSKLEEMYEERER 1321
Query: 564 DEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNE 622
+ ME+ E K + L+ K+Q V E +R+ ++ E+ + E
Sbjct: 1322 TSQEMEMLRKQVECLAEENGKLVGHQNLHQKIQYVVR----LKKENVRLAEETEKLRAE 1376
>gi|40254834 kinesin family member 1C [Homo sapiens]
Length = 1103
Score = 275 bits (702), Expect = 2e-73
Identities = 192/526 (36%), Positives = 285/526 (54%), Gaps = 79/526 (15%)
Query: 7 ASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVT-LRNPRAAPGELPKTFTFDAVYD 65
A ++KV R RP + +E + + +++M G T + NP+ + + PK+FTFD Y
Sbjct: 2 AGASVKVAVRVRPFNARETSQDAKCVVSMQ---GNTTSIINPKQSK-DAPKSFTFDYSYW 57
Query: 66 ASSKQAD--------LYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELR 117
+ + D +Y + ++ +G+N +FAYGQTG GK+YTM G EP +
Sbjct: 58 SHTSTEDPQFASQQQVYRDIGEEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGRQ-EPGQQ 116
Query: 118 GVIPNAFEHIFTHISRSQNQQ--YLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGV 175
G++P E +F+ +S +Q+ Q Y V SY+EIY E +RDLL+ + L ++E+P G
Sbjct: 117 GIVPQLCEDLFSRVSENQSAQLSYSVEVSYMEIYCERVRDLLNPKSRGSLRVREHPILGP 176
Query: 176 YIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFII--TVECSERGSDG 233
Y++DLS + +I +M+ GN+ R V +T+MNE SSRSHA+F I T C ++ + G
Sbjct: 177 YVQDLSKLAVTSYADIADLMDCGNKARTVAATNMNETSSRSHAVFTIVFTQRCHDQLT-G 235
Query: 234 QDHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKI 293
D +V K++LVDLAGSER + +G A G R KE + I
Sbjct: 236 LDSEKVSKISLVDLAGSERADSSG------------------------ARGMRLKEGANI 271
Query: 294 NLSLSALGNVIAALAG-----NRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHS 348
N SL+ LG VI+ALA +S IPYRDS LT LL+++LGGN++T M+A L PA +
Sbjct: 272 NKSLTTLGKVISALADMQSKKRKSDFIPYRDSVLTWLLKENLGGNSRTAMIAALSPADIN 331
Query: 349 YDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGML-----GKR 403
Y+E+LSTLR+A+R K I+ +NEDP L+RE QEE+ARL+ L +G+ G +
Sbjct: 332 YEETLSTLRYADRTKQIRCNAIINEDPNARLIRELQEEVARLRELLMAQGLSASALEGLK 391
Query: 404 PRRKSSR-RKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYL- 461
S R AVS+PP A V+ +N LE + N E+ +
Sbjct: 392 TEEGSVRGALPAVSSPP---------APVSPSSPTTHNGE------LEPSFSPNTESQIG 436
Query: 462 -QEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQA 506
+E ERL+E + I E + EEK + E LR E++A
Sbjct: 437 PEEAMERLQETEKII--------AELNETWEEKLRKTEALRMEREA 474
>gi|30794488 kinesin family member 27 [Homo sapiens]
Length = 1401
Score = 268 bits (684), Expect = 2e-71
Identities = 198/641 (30%), Positives = 325/641 (50%), Gaps = 118/641 (18%)
Query: 11 LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSKQ 70
+KV R RPL KE H+ + + QV + R FTFD V+ +S Q
Sbjct: 6 VKVAVRIRPLLCKEALHNHQVCVRVIPNSQQVIIGRDRV--------FTFDFVFGKNSTQ 57
Query: 71 ADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPEL---RGVIPNAFEHI 127
++Y+ ++PL+ S+++G+N TVFAYGQTG+GKTYT+ G + + +G+IP A + I
Sbjct: 58 DEVYNTCIKPLVLSLIEGYNATVFAYGQTGSGKTYTIGGGHIASVVEGQKGIIPRAIQEI 117
Query: 128 FTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPG-KRLELKENPETGVYIKDLSSFVTK 186
F IS + + V+ SY+E+Y+E++RDLL E K L ++E+ + I +
Sbjct: 118 FQSISEHPSIDFNVKVSYIEVYKEDLRDLLELETSMKDLHIREDEKGNTVIVGAKECHVE 177
Query: 187 NVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITV-------ECSERGSDGQDHIRV 239
+ E+ ++ +GN R G+T MNE SSRSHAIF I++ E +E GS V
Sbjct: 178 SAGEVMSLLEMGNAARHTGTTQMNEHSSRSHAIFTISICQVHKNMEAAEDGSWYSPRHIV 237
Query: 240 GKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSA 299
K + VDLAGSER K G NT GER KE+ +IN L A
Sbjct: 238 SKFHFVDLAGSERVTKTG-NT-----------------------GERFKESIQINSGLLA 273
Query: 300 LGNVIAALAGNR--STHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLR 357
LGNVI+AL R S+HIPYRD+K+TRLL+DSLGG+AKT+M+ + P+S ++DESL++L+
Sbjct: 274 LGNVISALGDPRRKSSHIPYRDAKITRLLKDSLGGSAKTVMITCVSPSSSNFDESLNSLK 333
Query: 358 FANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSA 417
+ANRA+NI+NKP VN P+ + E + EI L+ L+ +
Sbjct: 334 YANRARNIRNKPTVNFSPESDRIDEMEFEIKLLREALQSQ-------------------- 373
Query: 418 PPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQ- 476
+A V++ N E + + N + L+EQ +L+ E Q
Sbjct: 374 ----------QAGVSQTTQINR----------EGSPDTNRIHSLEEQVAQLQGECLGYQC 413
Query: 477 ------------DDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIG 524
D ++E++Q L+E M++++R+ + S IG
Sbjct: 414 CVEEAFTFLVDLKDTVRLNEKQQHKLQEWFNMIQEVRK------------AVLTSFRGIG 461
Query: 525 GRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVK 584
G ++ + +L+LKR E K+ + + + ++ +++ +E++ L+ +V++
Sbjct: 462 GTASLEEGPQHVTVLQLKR----ELKKCQCVLAADEVVFNQKELEVK----ELKNQVQMM 513
Query: 585 TKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTR 625
++ K L+ + + Q+++ I + +++ E T+
Sbjct: 514 VQENKGHAVSLKEAQKVNRLQNEKIIEQQLLVDQLSEELTK 554
Score = 35.4 bits (80), Expect = 0.21
Identities = 57/298 (19%), Positives = 125/298 (41%), Gaps = 63/298 (21%)
Query: 453 LEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLL--------EEKEKMLED-LRRE 503
L+K ++ + ++ EK A + ++S+ + QK+ EK K L+ ++R+
Sbjct: 817 LQKKQQDSKKLASLSIQNEKRANELEQSVDHMKYQKIQLQRKLREENEKRKQLDAVIKRD 876
Query: 504 QQATELLAAK-------------YKAMESKLLIGGRNIMDH---TNEQQKMLELKRQEIA 547
QQ + + K A K G +DH +EQ+K L+ + +++
Sbjct: 877 QQKIKEIQLKTGQEEGLKPKAEDLDACNLKRRKGSFGSIDHLQKLDEQKKWLDEEVEKVL 936
Query: 548 EQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLK----------KLYAKLQA 597
Q++ E++ ++ R+ + LQ++ ++ KKL+ K+ +L
Sbjct: 937 NQRQELEELEADLKKREAIVSKKEAL---LQEKSHLENKKLRSSQALNTDSLKISTRLNL 993
Query: 598 VKAEIQDQH--------DEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNR 649
++ E+ +++ +E ++ + +E Q E+ + K ++ + E K+ N
Sbjct: 994 LEQELSEKNVQLQTSTAEEKTKISEQVEVLQKEKDQLQKRRHNVDE---------KLKNG 1044
Query: 650 LFLDCEEEQWKFQPLVPAGVSSSQMKKRPTSAVGYKRPISQYARVAMAMGSHPRYRAE 707
L EEE FQ + G+ + + +A+ Y+ Q + ++ H R E
Sbjct: 1045 RVLSPEEEHVLFQ--LEEGIEALE------AAIEYRNESIQNRQKSLRASFHNLSRGE 1094
>gi|150010604 kinesin family member 4B [Homo sapiens]
Length = 1234
Score = 267 bits (682), Expect = 3e-71
Identities = 214/703 (30%), Positives = 340/703 (48%), Gaps = 100/703 (14%)
Query: 11 LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSKQ 70
++V RCRPL KE + G + L+ QV + K+FT+D V+D ++Q
Sbjct: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGETQVVVGTD--------KSFTYDFVFDPCTEQ 61
Query: 71 ADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWV-----EPELRGVIPNAFE 125
+++++ V PLI + +G+N TV AYGQTG+GKTY+M G + EP + G+IP +
Sbjct: 62 EEVFNKAVAPLIKGIFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTV-GIIPRVIQ 120
Query: 126 HIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGK-RLELKENPETGVYIKDLSSFV 184
+F I + + ++ ++ SYLEIY EEI DLL K ++ ++E+P+ G+ I L+
Sbjct: 121 LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT 180
Query: 185 TKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKLNL 244
+ + GN +R V ST MN SSRSHAIF I++E + SD R KL+L
Sbjct: 181 VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISIE-QRKKSDKNCSFR-SKLHL 238
Query: 245 VDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGNVI 304
VDLAGSERQ K A G+R KE IN L LGNVI
Sbjct: 239 VDLAGSERQKKTK------------------------AEGDRLKEGININRGLLCLGNVI 274
Query: 305 AALAGNRS-THIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAK 363
+AL ++ + +PYRDSKLTRLLQDSLGGN+ T+M+A + PA + +E+LSTLR+A+RA+
Sbjct: 275 SALGDDKKGSFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLSTLRYADRAR 334
Query: 364 NIKNKPRVNEDPKDTLLREFQEEIARLKAQL------------------------EKRGM 399
IKNKP VN DP L ++++ +L+ L EK
Sbjct: 335 KIKNKPIVNIDPHTAELNHLKQQVQQLQVLLLQAHGGTLPGSINAEPSENLQSLMEKNQS 394
Query: 400 LGKRPRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEED---DNNNNHRPPQPILESALEKN 456
L + + S KA E ++ V E+ + + H + L+ +E
Sbjct: 395 LVEENEKLSRCLSKAAGQTAQMLERIILTEQVNEKLNAKLEELRQHVACKLDLQKLVETL 454
Query: 457 MENYLQEQKE---RLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLE---DLRREQQATELL 510
+ L+E E L++ + D+ + E+E +E + R A
Sbjct: 455 EDQELKENVEIICNLQQLITQLSDETVACTAAAIDTAVEEEAQVETSPETSRSSDAFTTQ 514
Query: 511 AAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMEL 570
A ++A SK ++ E L LK + + + + ++Q + L
Sbjct: 515 HALHQAQMSKEVV----------ELNNALALKEALVRKMTQNDNQLQPIQFQYQDNIKNL 564
Query: 571 RGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQ----DLEEAQNEQTRE 626
+LQ+E E ++L+ AK +A++ + + ++ + DL++ NEQ++
Sbjct: 565 ELEVINLQKEKEELVRELQT--AKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKL 622
Query: 627 LKLK--------YLIIENFIPPEEKNKIMNRLFLDCEE-EQWK 660
LKLK L E ++ ++ ++M ++ D E+ QWK
Sbjct: 623 LKLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWK 665
Score = 43.1 bits (100), Expect = 0.001
Identities = 42/223 (18%), Positives = 100/223 (44%), Gaps = 30/223 (13%)
Query: 453 LEKNMENYLQEQKERLEEEKAAIQD-DRSLVSEEKQKLLEEKEKMLEDLRRE-------- 503
LE + N +E++E + E + A ++ +++ +SE + KLL+E E + DL+++
Sbjct: 564 LELEVINLQKEKEELVRELQTAKKNVNQAKLSEHRHKLLQELEGQIADLKKKLNEQSKLL 623
Query: 504 --QQATELLAAKYK----AMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQ 557
+++TE +K M+++ + R + + + ++ + K +E+ + K R+R+ Q
Sbjct: 624 KLKESTERTVSKLNQEIWMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQ 683
Query: 558 QEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAK---------------LQAVKAEI 602
E++ + + +E K+LK K + + A +
Sbjct: 684 YELLKLERNFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARV 743
Query: 603 QDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNK 645
++ I V EEA+ L+ + ++ ++ + +EK +
Sbjct: 744 RNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVVQLKEKKE 786
Score = 40.0 bits (92), Expect = 0.008
Identities = 70/350 (20%), Positives = 140/350 (40%), Gaps = 73/350 (20%)
Query: 372 NEDPKDTLLREFQEEIA----RLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPVI 427
N + ++LR EE A RLK L+K+ + + + S K+ ++A G I
Sbjct: 692 NFQKQSSVLRRKTEEAAAANKRLKDALQKQREVTDKRKETQSHGKEGIAARVRNWLGNEI 751
Query: 428 EAWVAEEEDDNN-NNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEK 486
E V+ EE + N+ + IL + + L+E+KE E ++ +SE
Sbjct: 752 EVMVSTEEAKRHLNDLLEDRKILAQDVVQ-----LKEKKESRENPPPKLRKCTFSLSEVH 806
Query: 487 QKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIG---------GRNIMD------- 530
++LE ++ + + + + EL +A+ ++ KLL NI
Sbjct: 807 GQVLESEDCITKQIESLETEMELRSAQIADLQQKLLDAESEDRPKQCWENIATILEAKCA 866
Query: 531 -------------HTNEQQKMLELKRQEIAEQKRR-----------EREMQQEMMLRDEE 566
H + + L + A+ ++ E E+Q E++ +++
Sbjct: 867 LKYLIGELVSSKIHVTKLENSLRQSKASCADMQKMLFEEQNHFSEIETELQAELVRMEQQ 926
Query: 567 TMELRGTYTSLQQEVEVKTKKLKKLYA-KLQAVKAEIQDQHDEYIRVRQDLEEAQN--EQ 623
E S QE ++ K+L+K + K Q + + +Q Q +E ++R+ E+ Q ++
Sbjct: 927 HQEKVLYLVSQLQESQMAEKQLEKSASEKEQQLVSTLQCQDEELEKMREVCEQNQQLLQE 986
Query: 624 TRELKLKYLIIE--------------------NFIPPEEKNKIMNRLFLD 653
+K K ++++ +IPP+ K + FL+
Sbjct: 987 NEIIKQKLILLQVASRQKHLPNDTLLSPDSSFEYIPPKPKPSRVKEKFLE 1036
>gi|116686122 kinesin family member 4 [Homo sapiens]
Length = 1232
Score = 266 bits (681), Expect = 4e-71
Identities = 215/704 (30%), Positives = 349/704 (49%), Gaps = 102/704 (14%)
Query: 11 LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSKQ 70
++V RCRPL KE + G + L+ QV + K+FT+D V+D S++Q
Sbjct: 10 VRVALRCRPLVPKEISEGCQMCLSFVPGEPQVVVGTD--------KSFTYDFVFDPSTEQ 61
Query: 71 ADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWV-----EPELRGVIPNAFE 125
++++ V PLI V +G+N TV AYGQTG+GKTY+M G + EP + GVIP +
Sbjct: 62 EEVFNTAVAPLIKGVFKGYNATVLAYGQTGSGKTYSMGGAYTAEQENEPTV-GVIPRVIQ 120
Query: 126 HIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGK-RLELKENPETGVYIKDLSSFV 184
+F I + + ++ ++ SYLEIY EEI DLL K ++ ++E+P+ G+ I L+
Sbjct: 121 LLFKEIDKKSDFEFTLKVSYLEIYNEEILDLLCPSREKAQINIREDPKEGIKIVGLTEKT 180
Query: 185 TKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKLNL 244
+ + GN +R V ST MN SSRSHAIF I++E + SD R KL+L
Sbjct: 181 VLVALDTVSCLEQGNNSRTVASTAMNSQSSRSHAIFTISLE-QRKKSDKNSSFR-SKLHL 238
Query: 245 VDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGNVI 304
VDLAGSERQ K A G+R KE IN L LGNVI
Sbjct: 239 VDLAGSERQKKTK------------------------AEGDRLKEGININRGLLCLGNVI 274
Query: 305 AALAGNRST-HIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAK 363
+AL ++ +PYRDSKLTRLLQDSLGGN+ T+M+A + PA + +E+L+TLR+A+RA+
Sbjct: 275 SALGDDKKGGFVPYRDSKLTRLLQDSLGGNSHTLMIACVSPADSNLEETLNTLRYADRAR 334
Query: 364 NIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKR------GMLGKRPR------------ 405
IKNKP VN DP+ L ++++ +L+ L + G + P
Sbjct: 335 KIKNKPIVNIDPQTAELNHLKQQVQQLQVLLLQAHGGTLPGSITVEPSENLQSLMEKNQS 394
Query: 406 --RKSSRRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQE 463
++ + + +S G ++E + E+ + N + + +A + +++ ++
Sbjct: 395 LVEENEKLSRGLSEAAG-QTAQMLERIILTEQANEKMNAKLEELRQHAACKLDLQKLVET 453
Query: 464 -QKERLEEEKAAIQDDRSLVSEEKQKLLE----------EKEKMLE---DLRREQQATEL 509
+ + L+E I + + L+++ + + E+E +E + R A
Sbjct: 454 LEDQELKENVEIICNLQQLITQLSDETVACMAAAIDTAVEQEAQVETSPETSRSSDAFTT 513
Query: 510 LAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETME 569
A +A SK L+ E K L LK + + + ++Q + E
Sbjct: 514 QHALRQAQMSKELV----------ELNKALALKEALARKMTQNDSQLQPIQYQYQDNIKE 563
Query: 570 LRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQ----DLEEAQNEQTR 625
L +LQ+E E +L+ AK A +A++ ++ + ++ + DL++ NEQ++
Sbjct: 564 LELEVINLQKEKEELVLELQT--AKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSK 621
Query: 626 ELKLK--------YLIIENFIPPEEKNKIMNRLFLDCEE-EQWK 660
LKLK L E + ++ ++M ++ D E+ QWK
Sbjct: 622 LLKLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWK 665
Score = 41.6 bits (96), Expect = 0.003
Identities = 45/223 (20%), Positives = 106/223 (47%), Gaps = 30/223 (13%)
Query: 453 LEKNMENYLQEQKERLEEEKAAIQD-DRSLVSEEKQKLLEEKEKMLEDLRRE-------- 503
LE + N +E++E + E + A +D +++ +SE ++K L+E E + DL+++
Sbjct: 564 LELEVINLQKEKEELVLELQTAKKDANQAKLSERRRKRLQELEGQIADLKKKLNEQSKLL 623
Query: 504 --QQATELLAAKY----KAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQ 557
+++TE +K + M+++ + R + + + ++ + K +E+ + K R+R+ Q
Sbjct: 624 KLKESTERTVSKLNQEIRMMKNQRVQLMRQMKEDAEKFRQWKQKKDKEVIQLKERDRKRQ 683
Query: 558 QEMM------------LR---DEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEI 602
E++ LR +E + +LQ++ EV K+ + ++ A +
Sbjct: 684 YELLKLERNFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARV 743
Query: 603 QDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNK 645
++ I V EEA+ L+ + ++ ++ +EK +
Sbjct: 744 KNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKE 786
Score = 37.7 bits (86), Expect = 0.042
Identities = 67/296 (22%), Positives = 118/296 (39%), Gaps = 53/296 (17%)
Query: 372 NEDPKDTLLREFQEEIA----RLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPVI 427
N + +LR EE A RLK L+K+ + + + SR + +A G I
Sbjct: 692 NFQKQSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQSRGMEGTAARVKNWLGNEI 751
Query: 428 EAWVAEEE-----------------------DDNNNNHRPPQPILESALE--------KN 456
E V+ EE + + PP +
Sbjct: 752 EVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPPKLRRRTFSLTEVRGQVSE 811
Query: 457 MENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATEL---LAAK 513
E+ + +Q E LE E ++ + +++ +QKLL+ + + R E AT L A K
Sbjct: 812 SEDSITKQIESLETE---MEFRSAQIADLQQKLLDAESEDRPKQRWENIATILEAKCALK 868
Query: 514 Y--------KAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDE 565
Y K SKL + + QKML +R AE E E+Q E++ ++
Sbjct: 869 YLIGELVSSKIQVSKLESSLKQSKTSCADMQKMLFEERNHFAE---IETELQAELVRMEQ 925
Query: 566 ETMELRGTYTSLQQEVEVKTKKLKK-LYAKLQAVKAEIQDQHDEYIRVRQDLEEAQ 620
+ E S Q+ ++ K+L++ + K Q + + ++ Q +E ++R+ E+ Q
Sbjct: 926 QHQEKVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQ 981
Score = 33.9 bits (76), Expect = 0.61
Identities = 30/108 (27%), Positives = 52/108 (48%), Gaps = 2/108 (1%)
Query: 468 LEEEKAAIQDDRSLVSEEKQKLLE-EKEKMLEDLRREQQATE-LLAAKYKAMESKLLIGG 525
L++ K + D + ++ EE+ E E E E +R EQQ E +L + +S++
Sbjct: 888 LKQSKTSCADMQKMLFEERNHFAEIETELQAELVRMEQQHQEKVLYLLSQLQQSQMAEKQ 947
Query: 526 RNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELRGT 573
EQQ + LK Q+ +K RE Q + +LR+ E ++ + T
Sbjct: 948 LEESVSEKEQQLLSTLKCQDEELEKMREVCEQNQQLLRENEIIKQKLT 995
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 264 bits (675), Expect = 2e-70
Identities = 221/710 (31%), Positives = 338/710 (47%), Gaps = 128/710 (18%)
Query: 10 ALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVT-LRNPRAAPG----ELPKTFTFD-AV 63
++KV R RP++R+E+ + I+ M+ +T L+ P G E KTFT+D +
Sbjct: 3 SVKVAVRVRPMNRREKDLEAKFIIQMEKSKTTITNLKIPEGGTGDSGRERTKTFTYDFSF 62
Query: 64 YDASSKQADLYDETV------RPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELR 117
Y A +K D + + ++ S +G+N VFAYGQTG+GK+YTM G +
Sbjct: 63 YSADTKSPDYVSQEMVFKTLGTDVVKSAFEGYNACVFAYGQTGSGKSYTMMGNSGDS--- 119
Query: 118 GVIPNAFEHIFTHIS---RSQNQQYLVRASYLEIYQEEIRDLLSKEPGK--RLELKENPE 172
G+IP E +F+ I+ R + SYLEIY E +RDLL ++ K L ++E+P+
Sbjct: 120 GLIPRICEGLFSRINETTRWDEASFRTEVSYLEIYNERVRDLLRRKSSKTFNLRVREHPK 179
Query: 173 TGVYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSD 232
G Y++DLS + +N ++E +M+ GN R +T MN+VSSRSHAIF T++ ++ D
Sbjct: 180 EGPYVEDLSKHLVQNYGDVEELMDAGNINRTTAATGMNDVSSRSHAIF--TIKFTQAKFD 237
Query: 233 GQDHIR-VGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEAS 291
+ V K++LVDLAGSER + G A G R KE
Sbjct: 238 SEMPCETVSKIHLVDLAGSERADATG------------------------ATGVRLKEGG 273
Query: 292 KINLSLSALGNVIAALAG-----------NRSTHIPYRDSKLTRLLQDSLGGNAKTIMVA 340
IN SL LGNVI+ALA + +PYRDS LT LL+DSLGGN+KTIM+A
Sbjct: 274 NINKSLVTLGNVISALADLSQDAANTLAKKKQVFVPYRDSVLTWLLKDSLGGNSKTIMIA 333
Query: 341 TLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGML 400
T+ PA +Y E+LSTLR+ANRAKNI NKP +NED L+RE + EIARLK L + +
Sbjct: 334 TISPADVNYGETLSTLRYANRAKNIINKPTINEDANVKLIRELRAEIARLKTLLAQGNQI 393
Query: 401 G--KRPRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILES---ALEK 455
P S K + EA V E + N Q IL+ AL K
Sbjct: 394 ALLDSPTALSMEEKLQQN-----------EARVQELTKEWTNKWNETQNILKEQTLALRK 442
Query: 456 N-------------------------MENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLL 490
+ +L+E + + + A+ + D L + L
Sbjct: 443 EGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDASTEQDIVLHGLD----L 498
Query: 491 EEKEKMLEDL------------RREQQATELLAAKYKAMESKLLIGGRNI--MDHTNEQQ 536
E + + E++ + +++ A + + +L+G N+ +H E
Sbjct: 499 ESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTNMFRFNHPKEAA 558
Query: 537 KMLELKRQEIAE-------QKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLK 589
K+ E ++ + + RE +ML + +E +++E K K ++
Sbjct: 559 KLREKRKSGLLSSFSLSMTDLSKSRENLSAVMLYN-PGLEFERQQREELEKLESKRKLIE 617
Query: 590 KLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQ---NEQTRELKLKYLIIEN 636
++ K ++ KAE++ E R++ E Q +Q LK + IEN
Sbjct: 618 EMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIEN 667
Score = 55.5 bits (132), Expect = 2e-07
Identities = 48/185 (25%), Positives = 92/185 (49%), Gaps = 18/185 (9%)
Query: 458 ENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLE-EKEKMLEDLRREQQATELLAAKYKA 516
E +E+ E+LE ++ I++ EEKQK + E E+M +++ +++ TE++ + +
Sbjct: 599 ERQQREELEKLESKRKLIEE-----MEEKQKSDKAELERMQQEVETQRKETEIVQLQIRK 653
Query: 517 MESKLLIGGRNI----MDHTNEQQKMLELK---RQEIAEQKRRERE-----MQQEMMLRD 564
E L +I D E++K E + +QEI QK+R+ E +Q+E+
Sbjct: 654 QEESLKRRSFHIENKLKDLLAEKEKFEEERLREQQEIELQKKRQEEETFLRVQEELQRLK 713
Query: 565 EETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQT 624
E + + QE++ K+ + YAKL+ K +++Q E + + LEE E+
Sbjct: 714 ELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQ 773
Query: 625 RELKL 629
++L
Sbjct: 774 EMIQL 778
Score = 43.9 bits (102), Expect = 6e-04
Identities = 100/472 (21%), Positives = 197/472 (41%), Gaps = 99/472 (20%)
Query: 351 ESLSTLRFANRAKNIKNKPRVNEDP---KDTLLREFQEEIARLKAQLEKRGMLGKRPRRK 407
E+LS + N + + R + K L+ E +E+ KA+LE+ +
Sbjct: 584 ENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERM------QQEV 637
Query: 408 SSRRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESAL---EKNMENYLQEQ 464
++RK E +++ + ++E+ + L+ L EK E L+EQ
Sbjct: 638 ETQRK----------ETEIVQLQIRKQEESLKRRSFHIENKLKDLLAEKEKFEEERLREQ 687
Query: 465 KERLEEEKAAIQDDRSLVSEEKQKLLE-------EKEKMLEDL------RREQQA-TELL 510
+E ++K ++ V EE Q+L E EK ++ ++L + EQ A EL
Sbjct: 688 QEIELQKKRQEEETFLRVQEELQRLKELNNNEKAEKFQIFQELDQLQKEKDEQYAKLELE 747
Query: 511 AAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQ---EIAEQKRREREMQQEMMLR---- 563
+ + E + ++ ++ + E+Q+M++L R+ + E+++R+ E +E +LR
Sbjct: 748 KKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQWVEEEKRDLEGIRESLLRVKEA 807
Query: 564 ----DEETMELR------------------GTYTSLQQEVEVKTKKLKKLYAKLQAVKAE 601
DE+ EL L Q+ ++ K++++ L+ +K E
Sbjct: 808 RAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQQKDILKKEVQEEQEILECLKCE 867
Query: 602 ------IQDQHDEYI----RVRQDLEEAQ----NEQTRELKLKYLIIENFIPP--EEKNK 645
+ ++HDE + V QD E+ + Q +E +L+YL ++N +P EEK +
Sbjct: 868 HDKESRLLEKHDESVTDVTEVPQDFEKIKPVEYRLQYKERQLQYL-LQNHLPTLLEEKQR 926
Query: 646 ---IMNRLFLDCEEEQWKFQPLVPAGVSSSQMKKRPTSAVGYKRPISQYARVAMAMGSHP 702
I++R L + ++ + +M+++ Y+ +Q ++
Sbjct: 927 AFEILDRGPLSLDNTLYQVE---------KEMEEKEEQLAQYQANANQLQKLQATFEF-- 975
Query: 703 RYRAENIMFLELDVSPPAVFEMEFSHDQEQDPRALHMERLMRLDSFLERPST 754
NI E V +E Q+++ + RL R S L+R ST
Sbjct: 976 ---TANIARQEEKVRKKEKEILESREKQQREALERALARLERRHSALQRHST 1024
Score = 35.4 bits (80), Expect = 0.21
Identities = 32/147 (21%), Positives = 71/147 (48%), Gaps = 18/147 (12%)
Query: 450 ESALEKNMENYLQ---EQKERLEE--EKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQ 504
E L+ ++N+L E+K+R E ++ + D +L EK+ +EEKE+ L +
Sbjct: 906 ERQLQYLLQNHLPTLLEEKQRAFEILDRGPLSLDNTLYQVEKE--MEEKEEQLAQYQANA 963
Query: 505 QATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRD 564
+ L A ++ NI +++K+ + +++ + +++++RE + + R
Sbjct: 964 NQLQKLQATFEFTA--------NI---ARQEEKVRKKEKEILESREKQQREALERALARL 1012
Query: 565 EETMELRGTYTSLQQEVEVKTKKLKKL 591
E +++L E+E + +KL L
Sbjct: 1013 ERRHSALQRHSTLGMEIEEQRQKLASL 1039
>gi|46852172 kinesin family member 13B [Homo sapiens]
Length = 1826
Score = 262 bits (670), Expect = 8e-70
Identities = 163/409 (39%), Positives = 240/409 (58%), Gaps = 53/409 (12%)
Query: 11 LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGEL---PKTFTFDAVY--- 64
+KV R RP++R+E + ++ +D + N + G+ PK F +D +
Sbjct: 6 VKVAVRIRPMNRRETDLHTKCVVDVDANKVILNPVNTNLSKGDARGQPKVFAYDHCFWSM 65
Query: 65 DASSKQADLYDETV-----RPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGV 119
D S K+ + V ++ + G+N +FAYGQTG+GK+YTM GT +P G+
Sbjct: 66 DESVKEKYAGQDIVFKCLGENILQNAFDGYNACIFAYGQTGSGKSYTMMGTADQP---GL 122
Query: 120 IPNAFEHIFTHISRSQN--QQYLVRASYLEIYQEEIRDLLSKEPGKR-LELKENPETGVY 176
IP +F + +N Q + V SY+EIY E++RDLL + ++ L+++E+ G Y
Sbjct: 123 IPRLCSGLFERTQKEENEEQSFKVEVSYMEIYNEKVRDLLDPKGSRQTLKVREHSVLGPY 182
Query: 177 IKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECS----ERGSD 232
+ LS + K+IE +M+ GN++R V +T+MNE SSRSHA+F IT+ + + G+
Sbjct: 183 VDGLSKLAVTSYKDIESLMSEGNKSRTVAATNMNEESSRSHAVFKITLTHTLYDVKSGTS 242
Query: 233 GQDHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASK 292
G+ +VGKL+LVDLAGSER K G A G+R KE S
Sbjct: 243 GE---KVGKLSLVDLAGSERATKTG------------------------AAGDRLKEGSN 275
Query: 293 INLSLSALGNVIAALAG-----NRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASH 347
IN SL+ LG VI+ALA N++ +PYRDS LT LL+DSLGGN+KT MVAT+ PA+
Sbjct: 276 INKSLTTLGLVISALADQSAGKNKNKFVPYRDSVLTWLLKDSLGGNSKTAMVATVSPAAD 335
Query: 348 SYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEK 396
+YDE+LSTLR+A+RAK+I N VNEDP ++R+ +EE+ +L+ QL K
Sbjct: 336 NYDETLSTLRYADRAKHIVNHAVVNEDPNARIIRDLREEVEKLREQLTK 384
>gi|41393559 kinesin family member 1B isoform alpha [Homo sapiens]
Length = 1153
Score = 260 bits (664), Expect = 4e-69
Identities = 159/408 (38%), Positives = 238/408 (58%), Gaps = 48/408 (11%)
Query: 10 ALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSK 69
++KV R RP + +E + + I+ M ++ NP+ P E PK+F+FD Y + +
Sbjct: 5 SVKVAVRVRPFNSRETSKESKCIIQMQGN--STSIINPKN-PKEAPKSFSFDYSYWSHTS 61
Query: 70 QAD--------LYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIP 121
D +Y++ + ++ +G+N +FAYGQTG GK+YTM G E + G+IP
Sbjct: 62 PEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQA-GIIP 120
Query: 122 NAFEHIFTHISRSQNQQ--YLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKD 179
E +F I+ + N++ Y V SY+EIY E +RDLL+ + L ++E+P G Y++D
Sbjct: 121 QLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVED 180
Query: 180 LSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHI-- 237
LS + +I +M+ GN+ R V +T+MNE SSRSHA+F T+ +++ D + ++
Sbjct: 181 LSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVF--TIVFTQKKHDNETNLST 238
Query: 238 -RVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLS 296
+V K++LVDLAGSER + G A G R KE + IN S
Sbjct: 239 EKVSKISLVDLAGSERADSTG------------------------AKGTRLKEGANINKS 274
Query: 297 LSALGNVIAALAG-----NRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDE 351
L+ LG VI+ALA ++ IPYRDS LT LL+++LGGN++T MVA L PA +YDE
Sbjct: 275 LTTLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDE 334
Query: 352 SLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGM 399
+LSTLR+A+RAK IK +NEDP L+RE +EE+ RLK L +G+
Sbjct: 335 TLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGL 382
>gi|41393563 kinesin family member 1B isoform b [Homo sapiens]
Length = 1770
Score = 260 bits (664), Expect = 4e-69
Identities = 159/408 (38%), Positives = 238/408 (58%), Gaps = 48/408 (11%)
Query: 10 ALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSK 69
++KV R RP + +E + + I+ M ++ NP+ P E PK+F+FD Y + +
Sbjct: 5 SVKVAVRVRPFNSRETSKESKCIIQMQGN--STSIINPKN-PKEAPKSFSFDYSYWSHTS 61
Query: 70 QAD--------LYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIP 121
D +Y++ + ++ +G+N +FAYGQTG GK+YTM G E + G+IP
Sbjct: 62 PEDPCFASQNRVYNDIGKEMLLHAFEGYNVCIFAYGQTGAGKSYTMMGKQEESQA-GIIP 120
Query: 122 NAFEHIFTHISRSQNQQ--YLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKD 179
E +F I+ + N++ Y V SY+EIY E +RDLL+ + L ++E+P G Y++D
Sbjct: 121 QLCEELFEKINDNCNEEMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPYVED 180
Query: 180 LSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHI-- 237
LS + +I +M+ GN+ R V +T+MNE SSRSHA+F T+ +++ D + ++
Sbjct: 181 LSKLAVTSYTDIADLMDAGNKARTVAATNMNETSSRSHAVF--TIVFTQKKHDNETNLST 238
Query: 238 -RVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLS 296
+V K++LVDLAGSER + G A G R KE + IN S
Sbjct: 239 EKVSKISLVDLAGSERADSTG------------------------AKGTRLKEGANINKS 274
Query: 297 LSALGNVIAALAG-----NRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDE 351
L+ LG VI+ALA ++ IPYRDS LT LL+++LGGN++T MVA L PA +YDE
Sbjct: 275 LTTLGKVISALAEVSKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAALSPADINYDE 334
Query: 352 SLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGM 399
+LSTLR+A+RAK IK +NEDP L+RE +EE+ RLK L +G+
Sbjct: 335 TLSTLRYADRAKQIKCNAVINEDPNAKLVRELKEEVTRLKDLLRAQGL 382
>gi|19924175 axonal transport of synaptic vesicles [Homo sapiens]
Length = 1690
Score = 259 bits (662), Expect = 7e-69
Identities = 159/417 (38%), Positives = 238/417 (57%), Gaps = 54/417 (12%)
Query: 7 ASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDA 66
A ++KV R RP + +E + + I+ M T+ NP+ P E PK+F+FD Y +
Sbjct: 2 AGASVKVAVRVRPFNSREMSRDSKCIIQMSGST--TTIVNPKQ-PKETPKSFSFDYSYWS 58
Query: 67 SSKQADL--------YDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRG 118
+ D+ Y + ++ +G+N +FAYGQTG GK+YTM G E + +G
Sbjct: 59 HTSPEDINYASQKQVYRDIGEEMLQHAFEGYNVCIFAYGQTGAGKSYTMMGKQ-EKDQQG 117
Query: 119 VIPNAFEHIFTHIS--RSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVY 176
+IP E +F+ I+ + N Y V SY+EIY E +RDLL+ + L ++E+P G Y
Sbjct: 118 IIPQLCEDLFSRINDTTNDNMSYSVEVSYMEIYCERVRDLLNPKNKGNLRVREHPLLGPY 177
Query: 177 IKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDH 236
++DLS + +I+ +M+ GN+ R V +T+MNE SSRSHA+F I +++ D + +
Sbjct: 178 VEDLSKLAVTSYNDIQDLMDSGNKARTVAATNMNETSSRSHAVFNIIF--TQKRHDAETN 235
Query: 237 I---RVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKI 293
I +V K++LVDLAGSER + G A G R KE + I
Sbjct: 236 ITTEKVSKISLVDLAGSERADSTG------------------------AKGTRLKEGANI 271
Query: 294 NLSLSALGNVIAALAG-----------NRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATL 342
N SL+ LG VI+ALA ++ IPYRDS LT LL+++LGGN++T MVA L
Sbjct: 272 NKSLTTLGKVISALAEMDSGPNKNKKKKKTDFIPYRDSVLTWLLRENLGGNSRTAMVAAL 331
Query: 343 GPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGM 399
PA +YDE+LSTLR+A+RAK I+ +NEDP + L+RE ++E+ RL+ L +G+
Sbjct: 332 SPADINYDETLSTLRYADRAKQIRCNAVINEDPNNKLIRELKDEVTRLRDLLYAQGL 388
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 254 bits (648), Expect = 3e-67
Identities = 186/555 (33%), Positives = 270/555 (48%), Gaps = 95/555 (17%)
Query: 7 ASEA-LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYD 65
A EA ++V R RPL KE GH+ L ++ LG+VTL R F F V
Sbjct: 11 AEEAPVRVALRVRPLLPKELLHGHQSCLQVEPGLGRVTLGRDRH--------FGFHVVLA 62
Query: 66 ASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPEL---RGVIPN 122
+ Q +Y V+PL+++ +GFN TVFAYGQTG+GKTYTM V L +G++P
Sbjct: 63 EDAGQEAVYQACVQPLLEAFFEGFNATVFAYGQTGSGKTYTMGEASVASLLEDEQGIVPR 122
Query: 123 AFEHIFTHISRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKR-LELKENPETGVYIKDLS 181
A F I + LV SYLE+Y+EE RDLL R ++L+E+ V + +
Sbjct: 123 AMAEAFKLIDENDLLDCLVHVSYLEVYKEEFRDLLEVGTASRDIQLREDERGNVVLCGVK 182
Query: 182 SFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSD-----GQDH 236
+ + E+ ++ +GN R G+TH+N +SSRSH +F +T+E R
Sbjct: 183 EVDVEGLDEVLSLLEMGNAARHTGATHLNHLSSRSHTVFTVTLEQRGRAPSRLPRPAPGQ 242
Query: 237 IRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLS 296
+ V K + VDLAGSER K G GER KE+ +IN S
Sbjct: 243 LLVSKFHFVDLAGSERVLKTGST------------------------GERLKESIQINSS 278
Query: 297 LSALGNVIAALAG--NRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLS 354
L ALGNVI+AL R +HIPYRDSK+TR+L+DSLGGNAKT+M+A + P+S +DE+L+
Sbjct: 279 LLALGNVISALGDPQRRGSHIPYRDSKITRILKDSLGGNAKTVMIACVSPSSSDFDETLN 338
Query: 355 TLRFANRAKNIKNKPRVN------EDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKS 408
TL +A+RA+NI+N+ VN P++T R + ++ RG P S
Sbjct: 339 TLNYASRAQNIRNRATVNWRPEAERPPEETASGARGPPRHRSETRIIHRGRRAPGPATAS 398
Query: 409 SRRK---------------------KAVSAPPGYPEGPV--IEAWVAEEEDDNN--NNHR 443
+ + + A PG P + W+ E + + ++
Sbjct: 399 AAAAMRLGAECARYRACTDAAYSLLRELQAEPGLPGAAARKVRDWLCAVEGERSALSSAS 458
Query: 444 PPQPILESALEKNMENY----------------LQEQKERLEEEK----AAIQDDRSLVS 483
P +ESA ++ LQ Q RLEEE AA++D
Sbjct: 459 GPDSGIESASVEDQAAQGAGGRKEDEGAQQLLTLQNQVARLEEENRDFLAALEDAMEQYK 518
Query: 484 EEKQKLLEEKEKMLE 498
+ +L E++E+M+E
Sbjct: 519 LQSDRLREQQEEMVE 533
Score = 46.6 bits (109), Expect = 9e-05
Identities = 41/158 (25%), Positives = 76/158 (48%), Gaps = 7/158 (4%)
Query: 439 NNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQD--DRSLVSEEKQKLLEEKEKM 496
N H LE E+ + Q++ E E +QD +RS + E ++++ + ++
Sbjct: 738 NRQHSQRIRELEQEAEQVRAELSEGQRQLRELEGKELQDAGERSRLQEFRRRVAAAQSQV 797
Query: 497 LEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREM 556
+ L+ ++QATE L + E +L RN+ +QQ L+ + +E EQKRR +
Sbjct: 798 -QVLKEKKQATERLVSLSAQSEKRLQELERNV-QLMRQQQGQLQRRLREETEQKRR---L 852
Query: 557 QQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAK 594
+ EM R EL + Q+ +++KT+++ K
Sbjct: 853 EAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRK 890
Score = 38.9 bits (89), Expect = 0.019
Identities = 43/178 (24%), Positives = 79/178 (44%), Gaps = 23/178 (12%)
Query: 462 QEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKL 521
Q Q + L+E+K A + SL S + +K L+E E+ ++ L R+QQ + + + +
Sbjct: 794 QSQVQVLKEKKQATERLVSL-SAQSEKRLQELERNVQ-LMRQQQGQLQRRLREETEQKRR 851
Query: 522 LIGGRNIMDHT--------NEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELRGT 573
L + H +QQK+L++K +EIA +R+ R ++ E+ ++
Sbjct: 852 LEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRSGSNGSVVSLEQQQKIEEQ 911
Query: 574 YTSLQQEVE-------------VKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEE 618
L QE+E + K + + AK +A+ E + +R Q L E
Sbjct: 912 KKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALMQEKTGLESKRLRSSQALNE 969
Score = 35.4 bits (80), Expect = 0.21
Identities = 31/158 (19%), Positives = 73/158 (46%), Gaps = 3/158 (1%)
Query: 493 KEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKML-ELKRQEIAEQKR 551
KE+++ +L R +A + L ++ +L + +E Q+ L EL+ +E+ +
Sbjct: 720 KEELIGELVRTGKAAQALNRQHSQRIRELEQEAEQVRAELSEGQRQLRELEGKELQDAGE 779
Query: 552 RER--EMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEY 609
R R E ++ + + L+ + ++ V + + K+L + V+ Q Q
Sbjct: 780 RSRLQEFRRRVAAAQSQVQVLKEKKQATERLVSLSAQSEKRLQELERNVQLMRQQQGQLQ 839
Query: 610 IRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIM 647
R+R++ E+ + + K ++ + E + E++ KI+
Sbjct: 840 RRLREETEQKRRLEAEMSKRQHRVKELELKHEQQQKIL 877
Score = 30.8 bits (68), Expect = 5.1
Identities = 46/226 (20%), Positives = 95/226 (42%), Gaps = 54/226 (23%)
Query: 463 EQKERLEEEKAAIQD---DRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMES 519
EQK RLE E + Q + L E++QK+L+ K + + +R++++
Sbjct: 847 EQKRRLEAEMSKRQHRVKELELKHEQQQKILKIKTEEIAAFQRKRRS------------- 893
Query: 520 KLLIGGRNIMDHTNEQQKMLELKR-------QEIAEQKRREREMQQEMMLRDE------- 565
G N + EQQ+ +E ++ +++ +Q+R E+ +E+ R+
Sbjct: 894 -----GSNGSVVSLEQQQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEA 948
Query: 566 --------ETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEI-QDQHDEYIRVRQDL 616
E+ LR + +L +++ + +L+ L +L ++ Q ++R ++
Sbjct: 949 LMQEKTGLESKRLRSS-QALNEDIVRVSSRLEHLEKELSEKSGQLRQGSAQSQQQIRGEI 1007
Query: 617 EEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLFLDCEEEQWKFQ 662
+ + E+ LK + E K+ L EEE+ FQ
Sbjct: 1008 DSLRQEKDSLLKQRL---------EIDGKLRQGSLLSPEEERTLFQ 1044
>gi|157738629 kinesin family member 13A isoform d [Homo sapiens]
Length = 1749
Score = 247 bits (630), Expect = 3e-65
Identities = 158/411 (38%), Positives = 238/411 (57%), Gaps = 58/411 (14%)
Query: 11 LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNP-----RAAPGELPKTFTFDAVY- 64
+KV R RP++R+E + ++ M+ G T+ +P + + PK F FD +
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEME---GNQTVLHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 65 --DASSKQADLYDETV-----RPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELR 117
D S+ E V +++ QG+N +FAYGQTG+GK+++M G E
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMG---HAEQL 119
Query: 118 GVIPNAFEHIFTHISRSQN--QQYLVRASYLEIYQEEIRDLLSKEPGKR-LELKENPETG 174
G+IP +F IS QN Q + V SY+EIY E++RDLL + ++ L+++E+ G
Sbjct: 120 GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVLG 179
Query: 175 VYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECS----ERG 230
Y+ LS + ++IE +M+ GN++R V +T+MNE SSRSHA+F I + + + G
Sbjct: 180 PYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSG 239
Query: 231 SDGQDHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEA 290
+ G+ +V K++LVDLAGSER +K G A GER KE
Sbjct: 240 NSGE---KVSKVSLVDLAGSERVSKTG------------------------AAGERLKEG 272
Query: 291 SKINLSLSALGNVIAALAGN-----RSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPA 345
S IN SL+ LG VI++LA +S +PYRDS LT LL+D+LGGN++T M+AT+ PA
Sbjct: 273 SNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPA 332
Query: 346 SHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEK 396
+ +Y+E+LSTLR+A+RAK I N VNEDP ++RE +EE+ +L+ QL +
Sbjct: 333 ADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQ 383
Score = 30.8 bits (68), Expect = 5.1
Identities = 51/252 (20%), Positives = 100/252 (39%), Gaps = 55/252 (21%)
Query: 404 PRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKN-MENYLQ 462
P+RK K G PE + A A E D N + I+++ + ++N +Q
Sbjct: 544 PKRKRRDWLKDFEKETGPPEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQ 603
Query: 463 E-QKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKL 521
+K+ LEE+++A+++ R + E ++L ++++ D + + + LA + + K+
Sbjct: 604 VLEKQYLEEKRSALEEQRLMYERELEQL---RQQLSPDRQPQSSGPDRLAYSSQTAQQKV 660
Query: 522 ---------------------LIGGRNIMDHTN----EQQKMLEL--------------- 541
L+ ++ N E K+ +
Sbjct: 661 TQWAEERDELFRQSLAKLREQLVKANTLVREANFLAEEMSKLTDYQVTLQIPAANLSANR 720
Query: 542 KR----QEIAEQKRREREMQQEMMLR--DEETMELRGTYTSLQQEVEVKTKKLKKLYAKL 595
KR E A Q RR+ + Q + + + +++R Y QE + K + K+LY K
Sbjct: 721 KRGAIVSEPAIQVRRKGKSTQVWTIEKLENKLIDMRDLY----QEWKEKVPEAKRLYGKR 776
Query: 596 QAVKAEIQDQHD 607
E Q+ H+
Sbjct: 777 GDPFYEAQENHN 788
>gi|157738627 kinesin family member 13A isoform c [Homo sapiens]
Length = 1757
Score = 247 bits (630), Expect = 3e-65
Identities = 158/411 (38%), Positives = 238/411 (57%), Gaps = 58/411 (14%)
Query: 11 LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNP-----RAAPGELPKTFTFDAVY- 64
+KV R RP++R+E + ++ M+ G T+ +P + + PK F FD +
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEME---GNQTVLHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 65 --DASSKQADLYDETV-----RPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELR 117
D S+ E V +++ QG+N +FAYGQTG+GK+++M G E
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMG---HAEQL 119
Query: 118 GVIPNAFEHIFTHISRSQN--QQYLVRASYLEIYQEEIRDLLSKEPGKR-LELKENPETG 174
G+IP +F IS QN Q + V SY+EIY E++RDLL + ++ L+++E+ G
Sbjct: 120 GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVLG 179
Query: 175 VYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECS----ERG 230
Y+ LS + ++IE +M+ GN++R V +T+MNE SSRSHA+F I + + + G
Sbjct: 180 PYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSG 239
Query: 231 SDGQDHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEA 290
+ G+ +V K++LVDLAGSER +K G A GER KE
Sbjct: 240 NSGE---KVSKVSLVDLAGSERVSKTG------------------------AAGERLKEG 272
Query: 291 SKINLSLSALGNVIAALAGN-----RSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPA 345
S IN SL+ LG VI++LA +S +PYRDS LT LL+D+LGGN++T M+AT+ PA
Sbjct: 273 SNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPA 332
Query: 346 SHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEK 396
+ +Y+E+LSTLR+A+RAK I N VNEDP ++RE +EE+ +L+ QL +
Sbjct: 333 ADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQ 383
Score = 30.8 bits (68), Expect = 5.1
Identities = 51/252 (20%), Positives = 100/252 (39%), Gaps = 55/252 (21%)
Query: 404 PRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKN-MENYLQ 462
P+RK K G PE + A A E D N + I+++ + ++N +Q
Sbjct: 544 PKRKRRDWLKDFEKETGPPEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQ 603
Query: 463 E-QKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKL 521
+K+ LEE+++A+++ R + E ++L ++++ D + + + LA + + K+
Sbjct: 604 VLEKQYLEEKRSALEEQRLMYERELEQL---RQQLSPDRQPQSSGPDRLAYSSQTAQQKV 660
Query: 522 ---------------------LIGGRNIMDHTN----EQQKMLEL--------------- 541
L+ ++ N E K+ +
Sbjct: 661 TQWAEERDELFRQSLAKLREQLVKANTLVREANFLAEEMSKLTDYQVTLQIPAANLSANR 720
Query: 542 KR----QEIAEQKRREREMQQEMMLR--DEETMELRGTYTSLQQEVEVKTKKLKKLYAKL 595
KR E A Q RR+ + Q + + + +++R Y QE + K + K+LY K
Sbjct: 721 KRGAIVSEPAIQVRRKGKSTQVWTIEKLENKLIDMRDLY----QEWKEKVPEAKRLYGKR 776
Query: 596 QAVKAEIQDQHD 607
E Q+ H+
Sbjct: 777 GDPFYEAQENHN 788
>gi|157738625 kinesin family member 13A isoform b [Homo sapiens]
Length = 1770
Score = 247 bits (630), Expect = 3e-65
Identities = 158/411 (38%), Positives = 238/411 (57%), Gaps = 58/411 (14%)
Query: 11 LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNP-----RAAPGELPKTFTFDAVY- 64
+KV R RP++R+E + ++ M+ G T+ +P + + PK F FD +
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEME---GNQTVLHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 65 --DASSKQADLYDETV-----RPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELR 117
D S+ E V +++ QG+N +FAYGQTG+GK+++M G E
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMG---HAEQL 119
Query: 118 GVIPNAFEHIFTHISRSQN--QQYLVRASYLEIYQEEIRDLLSKEPGKR-LELKENPETG 174
G+IP +F IS QN Q + V SY+EIY E++RDLL + ++ L+++E+ G
Sbjct: 120 GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVLG 179
Query: 175 VYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECS----ERG 230
Y+ LS + ++IE +M+ GN++R V +T+MNE SSRSHA+F I + + + G
Sbjct: 180 PYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSG 239
Query: 231 SDGQDHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEA 290
+ G+ +V K++LVDLAGSER +K G A GER KE
Sbjct: 240 NSGE---KVSKVSLVDLAGSERVSKTG------------------------AAGERLKEG 272
Query: 291 SKINLSLSALGNVIAALAGN-----RSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPA 345
S IN SL+ LG VI++LA +S +PYRDS LT LL+D+LGGN++T M+AT+ PA
Sbjct: 273 SNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPA 332
Query: 346 SHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEK 396
+ +Y+E+LSTLR+A+RAK I N VNEDP ++RE +EE+ +L+ QL +
Sbjct: 333 ADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQ 383
Score = 30.8 bits (68), Expect = 5.1
Identities = 51/252 (20%), Positives = 100/252 (39%), Gaps = 55/252 (21%)
Query: 404 PRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKN-MENYLQ 462
P+RK K G PE + A A E D N + I+++ + ++N +Q
Sbjct: 544 PKRKRRDWLKDFEKETGPPEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQ 603
Query: 463 E-QKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKL 521
+K+ LEE+++A+++ R + E ++L ++++ D + + + LA + + K+
Sbjct: 604 VLEKQYLEEKRSALEEQRLMYERELEQL---RQQLSPDRQPQSSGPDRLAYSSQTAQQKV 660
Query: 522 ---------------------LIGGRNIMDHTN----EQQKMLEL--------------- 541
L+ ++ N E K+ +
Sbjct: 661 TQWAEERDELFRQSLAKLREQLVKANTLVREANFLAEEMSKLTDYQVTLQIPAANLSANR 720
Query: 542 KR----QEIAEQKRREREMQQEMMLR--DEETMELRGTYTSLQQEVEVKTKKLKKLYAKL 595
KR E A Q RR+ + Q + + + +++R Y QE + K + K+LY K
Sbjct: 721 KRGAIVSEPAIQVRRKGKSTQVWTIEKLENKLIDMRDLY----QEWKEKVPEAKRLYGKR 776
Query: 596 QAVKAEIQDQHD 607
E Q+ H+
Sbjct: 777 GDPFYEAQENHN 788
>gi|157738621 kinesin family member 13A isoform a [Homo sapiens]
Length = 1805
Score = 247 bits (630), Expect = 3e-65
Identities = 158/411 (38%), Positives = 238/411 (57%), Gaps = 58/411 (14%)
Query: 11 LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNP-----RAAPGELPKTFTFDAVY- 64
+KV R RP++R+E + ++ M+ G T+ +P + + PK F FD +
Sbjct: 6 VKVAVRVRPMNRRELELNTKCVVEME---GNQTVLHPPPSNTKQGERKPPKVFAFDYCFW 62
Query: 65 --DASSKQADLYDETV-----RPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELR 117
D S+ E V +++ QG+N +FAYGQTG+GK+++M G E
Sbjct: 63 SMDESNTTKYAGQEVVFKCLGEGILEKAFQGYNACIFAYGQTGSGKSFSMMG---HAEQL 119
Query: 118 GVIPNAFEHIFTHISRSQN--QQYLVRASYLEIYQEEIRDLLSKEPGKR-LELKENPETG 174
G+IP +F IS QN Q + V SY+EIY E++RDLL + ++ L+++E+ G
Sbjct: 120 GLIPRLCCALFKRISLEQNESQTFKVEVSYMEIYNEKVRDLLDPKGSRQSLKVREHKVLG 179
Query: 175 VYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECS----ERG 230
Y+ LS + ++IE +M+ GN++R V +T+MNE SSRSHA+F I + + + G
Sbjct: 180 PYVDGLSQLAVTSFEDIESLMSEGNKSRTVAATNMNEESSRSHAVFNIIITQTLYDLQSG 239
Query: 231 SDGQDHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEA 290
+ G+ +V K++LVDLAGSER +K G A GER KE
Sbjct: 240 NSGE---KVSKVSLVDLAGSERVSKTG------------------------AAGERLKEG 272
Query: 291 SKINLSLSALGNVIAALAGN-----RSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPA 345
S IN SL+ LG VI++LA +S +PYRDS LT LL+D+LGGN++T M+AT+ PA
Sbjct: 273 SNINKSLTTLGLVISSLADQAAGKGKSKFVPYRDSVLTWLLKDNLGGNSQTSMIATISPA 332
Query: 346 SHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEK 396
+ +Y+E+LSTLR+A+RAK I N VNEDP ++RE +EE+ +L+ QL +
Sbjct: 333 ADNYEETLSTLRYADRAKRIVNHAVVNEDPNAKVIRELREEVEKLREQLSQ 383
Score = 30.8 bits (68), Expect = 5.1
Identities = 51/252 (20%), Positives = 100/252 (39%), Gaps = 55/252 (21%)
Query: 404 PRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKN-MENYLQ 462
P+RK K G PE + A A E D N + I+++ + ++N +Q
Sbjct: 544 PKRKRRDWLKDFEKETGPPEHDLDAASEASSEPDYNYEFAQMEVIMKTLNSNDPVQNVVQ 603
Query: 463 E-QKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKL 521
+K+ LEE+++A+++ R + E ++L ++++ D + + + LA + + K+
Sbjct: 604 VLEKQYLEEKRSALEEQRLMYERELEQL---RQQLSPDRQPQSSGPDRLAYSSQTAQQKV 660
Query: 522 ---------------------LIGGRNIMDHTN----EQQKMLEL--------------- 541
L+ ++ N E K+ +
Sbjct: 661 TQWAEERDELFRQSLAKLREQLVKANTLVREANFLAEEMSKLTDYQVTLQIPAANLSANR 720
Query: 542 KR----QEIAEQKRREREMQQEMMLR--DEETMELRGTYTSLQQEVEVKTKKLKKLYAKL 595
KR E A Q RR+ + Q + + + +++R Y QE + K + K+LY K
Sbjct: 721 KRGAIVSEPAIQVRRKGKSTQVWTIEKLENKLIDMRDLY----QEWKEKVPEAKRLYGKR 776
Query: 596 QAVKAEIQDQHD 607
E Q+ H+
Sbjct: 777 GDPFYEAQENHN 788
>gi|45446749 kinesin family member 5A [Homo sapiens]
Length = 1032
Score = 244 bits (622), Expect = 3e-64
Identities = 188/614 (30%), Positives = 306/614 (49%), Gaps = 67/614 (10%)
Query: 3 SKTKASEALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDA 62
++T ++KV+ R RPL++ E G + I V P + FD
Sbjct: 2 AETNNECSIKVLCRFRPLNQAEILRGDKFIPIFQGDDSVVIGGKP----------YVFDR 51
Query: 63 VYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPN 122
V+ ++ Q +Y ++ VL G+NGT+FAYGQT +GKT+TM+G +P+L G+IP
Sbjct: 52 VFPPNTTQEQVYHACAMQIVKDVLAGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPR 111
Query: 123 AFEHIFTHI-SRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLS 181
IF HI S +N ++ ++ SY EIY ++IRDLL L + E+ ++K +
Sbjct: 112 IARDIFNHIYSMDENLEFHIKVSYFEIYLDKIRDLLDVTK-TNLSVHEDKNRVPFVKGCT 170
Query: 182 SFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGK 241
+ +EI V++ G R V T+MNE SSRSH+IF+I ++ ++ + GK
Sbjct: 171 ERFVSSPEEILDVIDEGKSNRHVAVTNMNEHSSRSHSIFLINIKQENMETEQK---LSGK 227
Query: 242 LNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALG 301
L LVDLAGSE+ +K G A G EA IN SLSALG
Sbjct: 228 LYLVDLAGSEKVSKTG------------------------AEGAVLDEAKNINKSLSALG 263
Query: 302 NVIAALAGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANR 361
NVI+ALA +++PYRDSK+TR+LQDSLGGN +T M P+S++ E+ STL F R
Sbjct: 264 NVISALAEGTKSYVPYRDSKMTRILQDSLGGNCRTTMFICCSPSSYNDAETKSTLMFGQR 323
Query: 362 AKNIKNKPRVN-EDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPG 420
AK IKN VN E + +++++E + KAQ E L + SR + + P
Sbjct: 324 AKTIKNTASVNLELTAEQWKKKYEKEKEKTKAQKETIAKL----EAELSRWRNGENVPET 379
Query: 421 ---YPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQD 477
E + A + EE N+N+ + E + E ++ ++L+++ I
Sbjct: 380 ERLAGEEAALGAELCEETPVNDNSSIVVRIAPEE--RQKYEEEIRRLYKQLDDKDDEINQ 437
Query: 478 DRSLVSEEKQKLLEEKEKMLE---DLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNE 534
L+ + KQ++L+++E ++ D + Q+ L ++ A + ++ + ++ E
Sbjct: 438 QSQLIEKLKQQMLDQEELLVSTRGDNEKVQRELSHLQSENDAAKDEV----KEVLQALEE 493
Query: 535 QQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEV----EVKTKKLKK 590
+ K QE+ E + QQ +L DE + ++ T SL+ E+ EV + K+
Sbjct: 494 LAVNYDQKSQEV------EEKSQQNQLLVDELSQKV-ATMLSLESELQRLQEVSGHQRKR 546
Query: 591 LYAKLQAVKAEIQD 604
+ L + ++ +
Sbjct: 547 IAEVLNGLMKDLSE 560
Score = 38.9 bits (89), Expect = 0.019
Identities = 39/190 (20%), Positives = 88/190 (46%), Gaps = 34/190 (17%)
Query: 455 KNMENYLQE---QKERLEEEKAAIQDDRSLVSEEK---QKLLEEKEKMLEDLRREQQATE 508
+++ Y+Q +K LEE ++ D+ + + ++ + L++KE +D ++A E
Sbjct: 641 RSLTEYMQSVELKKRHLEESYDSLSDELAKLQAQETVHEVALKDKEPDTQDADEVKKALE 700
Query: 509 LLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETM 568
L ++ + L + D NE+QK ++ +++ Q++ L E
Sbjct: 701 LQMESHREAHHRQLA---RLRDEINEKQKTID-----------ELKDLNQKLQL---ELE 743
Query: 569 ELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTRELK 628
+L+ Y L+ E K+ KL++L + ++H++ +QDL+ + REL+
Sbjct: 744 KLQADYEKLKSEEHEKSTKLQEL--------TFLYERHEQ---SKQDLKGLEETVARELQ 792
Query: 629 LKYLIIENFI 638
+ + + F+
Sbjct: 793 TLHNLRKLFV 802
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 243 bits (621), Expect = 4e-64
Identities = 161/394 (40%), Positives = 224/394 (56%), Gaps = 45/394 (11%)
Query: 10 ALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELP--KTFTFDAVYDAS 67
A+ V R RPL+ +EE+ G + QV + ++ K+F FD V+ +
Sbjct: 6 AVAVCVRVRPLNSREESLG---------ETAQVYWKTDNNVIYQVDGSKSFNFDRVFHGN 56
Query: 68 SKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEHI 127
++Y+E P+IDS +QG+NGT+FAYGQT +GKTYTM G+ E L GVIP A I
Sbjct: 57 ETTKNVYEEIAAPIIDSAIQGYNGTIFAYGQTASGKTYTMMGS--EDHL-GVIPRAIHDI 113
Query: 128 FTHISRSQNQQYLVRASYLEIYQEEIRDLL-SKEPGKRLELKENPETGVYIKDLSSFVTK 186
F I + ++++L+R SY+EIY E I DLL + K L ++E+ VY+ DL+ V
Sbjct: 114 FQKIKKFPDREFLLRVSYMEIYNETITDLLCGTQKMKPLIIREDVNRNVYVADLTEEVVY 173
Query: 187 NVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERG--SDGQDHIRVGKLNL 244
+ + G ++R G T MN+ SSRSH IF + +E E+G S+ + ++V LNL
Sbjct: 174 TSEMALKWITKGEKSRHYGETKMNQRSSRSHTIFRMILESREKGEPSNCEGSVKVSHLNL 233
Query: 245 VDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGNVI 304
VDLAGSER + GA G R KE IN SL LG VI
Sbjct: 234 VDLAGSERAAQT------------------------GAAGVRLKEGCNINRSLFILGQVI 269
Query: 305 AALA-GNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAK 363
L+ G I YRDSKLTR+LQ+SLGGNAKT ++ T+ P S+DE+L+ L+FA+ AK
Sbjct: 270 KKLSDGQVGGFINYRDSKLTRILQNSLGGNAKTRIICTITPV--SFDETLTALQFASTAK 327
Query: 364 NIKNKPRVNEDPKD-TLLREFQEEIARLKAQLEK 396
+KN P VNE D LL+ +++EI LK QLE+
Sbjct: 328 YMKNTPYVNEVSTDEALLKRYRKEIMDLKKQLEE 361
Score = 48.9 bits (115), Expect = 2e-05
Identities = 47/202 (23%), Positives = 99/202 (49%), Gaps = 25/202 (12%)
Query: 451 SALEKNMENYLQEQKERLEEEKAAIQDDRSLVS-----EEKQKLLEEKEKMLEDLRREQQ 505
S ++K++EN + +E+++E KA ++ L++ E QK + E E++ + ++ +
Sbjct: 1805 SNMQKDLENSNAKLQEKIQELKA---NEHQLITLKKDVNETQKKVSEMEQLKKQIKDQSL 1861
Query: 506 ATELLAAKYKAMESKL---LIGGRNIM---DHTNEQQKMLELKRQEIAEQ----KRRERE 555
L + + KL L +++M D+ ++ L+L+R ++ E K R+ E
Sbjct: 1862 TLSKLEIENLNLAQKLHENLEEMKSVMKERDNLRRVEETLKLERDQLKESLQETKARDLE 1921
Query: 556 MQQEMMLRDEETMELRGTYTSLQQEVEVKT-------KKLKKLYAKLQAVKAEIQDQHDE 608
+QQE+ + E + T L++++ KT K L K +LQ E+Q + +
Sbjct: 1922 IQQELKTARMLSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQ 1981
Query: 609 YIRVRQDLEEAQNEQTRELKLK 630
+RV++D+ + + +LK
Sbjct: 1982 LLRVKEDVNMSHKKINEMEQLK 2003
Score = 40.0 bits (92), Expect = 0.008
Identities = 34/192 (17%), Positives = 85/192 (44%), Gaps = 16/192 (8%)
Query: 461 LQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESK 520
L+EQ+E + E + + + + +S +++L +K+ ++ + E K + +
Sbjct: 1486 LKEQEETINELRVNLSEKETEISTIQKQLEAINDKLQNKIQEIYEKEEQFNIKQISEVQE 1545
Query: 521 LLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQE 580
+ + +H + L+ ++ E R +E Q+E+ + +E E++ +LQ E
Sbjct: 1546 KVNELKQFKEHRKAKDSALQSIESKMLELTNRLQESQEEIQIMIKEKEEMKRVQEALQIE 1605
Query: 581 VEVKTKKLKKLYAKLQAVKA------------EIQDQHDEYIRVRQDLE----EAQNEQT 624
+ + K++ AK++ + E Q++ E +++ E +N +T
Sbjct: 1606 RDQLKENTKEIVAKMKESQEKEYQFLKMTAVNETQEKMCEIEHLKEQFETQKLNLENIET 1665
Query: 625 RELKLKYLIIEN 636
++L ++ EN
Sbjct: 1666 ENIRLTQILHEN 1677
Score = 40.0 bits (92), Expect = 0.008
Identities = 39/192 (20%), Positives = 85/192 (44%), Gaps = 17/192 (8%)
Query: 455 KNMENYLQEQKERL-------EEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQAT 507
+ ++N +Q++ +R+ AI ++ + E + +E E +DL+ ++
Sbjct: 2283 EKLKNGIQKENDRICQVNNFFNNRIIAIMNESTEFEERSATISKEWE---QDLKSLKEKN 2339
Query: 508 ELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEET 567
E L Y+ +++ L G + ++ T + K + + + RE++ + E
Sbjct: 2340 EKLFKNYQTLKTSLASGAQ--VNPTTQDNKNPHVTSRATQLTTEKIRELENSLHEAKESA 2397
Query: 568 MELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDL----EEAQNEQ 623
M +Q+E+EV + KL AK+ + ++ E I+V QD + E+
Sbjct: 2398 MHKESKIIKMQKELEVTNDIIAKLQAKVHE-SNKCLEKTKETIQVLQDKVALGAKPYKEE 2456
Query: 624 TRELKLKYLIIE 635
+LK+K + I+
Sbjct: 2457 IEDLKMKLVKID 2468
Score = 39.3 bits (90), Expect = 0.014
Identities = 54/271 (19%), Positives = 123/271 (45%), Gaps = 53/271 (19%)
Query: 459 NYLQEQKERLEEEKAAIQD---DRSLVSEEKQKLLEEKEKML---EDLRREQQATELLAA 512
N +++ KE+LE + +Q +++L++E+ Q+ LEE + + +DL++ Q++ ++
Sbjct: 887 NEMEQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKDDLKQLQESLQIERD 946
Query: 513 KYKA-------MESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRR-----------ER 554
+ K+ M RN ++ + Q+ + + +I+E+ R +
Sbjct: 947 QLKSDIHDTVNMNIDTQEQLRNALESLKQHQETINTLKSKISEEVSRNLHMEENTGETKD 1006
Query: 555 EMQQEMM-------------------LRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKL 595
E QQ+M+ ++D E +E + SL QE + L+ + A+
Sbjct: 1007 EFQQKMVGIDKKQDLEAKNTQTLTADVKDNEIIEQQRKIFSLIQEKNELQQMLESVIAEK 1066
Query: 596 QAVKAEIQDQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPE-EKNKIMNRLFLDC 654
+ +K ++++ + I +++L +E ++ ++ + I E E ++ +RL +
Sbjct: 1067 EQLKTDLKENIEMTIENQEELRLLGDELKKQQEIVAQEKNHAIKKEGELSRTCDRL-AEV 1125
Query: 655 EEE--------QWKFQPLVPAGVSSSQMKKR 677
EE+ Q K Q L+ S+M+K+
Sbjct: 1126 EEKLKEKSQQLQEKQQQLLNVQEEMSEMQKK 1156
Score = 39.3 bits (90), Expect = 0.014
Identities = 42/178 (23%), Positives = 80/178 (44%), Gaps = 13/178 (7%)
Query: 466 ERLEEEKAAIQDDRSLVSEEKQKLLEE---KEKMLEDLRREQQATELLAAKYKAMES--K 520
E LEE ++ ++ L S E+ +E KE + E + R+ + E L + ++ +
Sbjct: 1676 ENLEEMRSVTKERDDLRSVEETLKVERDQLKENLRETITRDLEKQEELKIVHMHLKEHQE 1735
Query: 521 LLIGGRNIM-DHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQ 579
+ R I+ + TNE M + K ++ ++Q+E+ + E + T L+
Sbjct: 1736 TIDKLRGIVSEKTNEISNMQKDLEHSNDALKAQDLKIQEELRIAHMHLKEQQETIDKLRG 1795
Query: 580 EVEVKTKKLKKLY-------AKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTRELKLK 630
V KT KL + AKLQ E++ + I +++D+ E Q + + +LK
Sbjct: 1796 IVSEKTDKLSNMQKDLENSNAKLQEKIQELKANEHQLITLKKDVNETQKKVSEMEQLK 1853
Score = 38.9 bits (89), Expect = 0.019
Identities = 46/225 (20%), Positives = 105/225 (46%), Gaps = 24/225 (10%)
Query: 452 ALEKN----MENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKM---------LE 498
A EKN E L +RL E + +++ + E++Q+LL +E+M +E
Sbjct: 1102 AQEKNHAIKKEGELSRTCDRLAEVEEKLKEKSQQLQEKQQQLLNVQEEMSEMQKKINEIE 1161
Query: 499 DLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQ 558
+L+ E + EL + ME++ L + + ++ E + + K +++ ++ ++ E ++
Sbjct: 1162 NLKNELKNKEL---TLEHMETERLELAQKLNENYEEVKSI--TKERKVLKELQKSFETER 1216
Query: 559 EMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEE 618
+ + +E G T ++E+++ LK+ + ++ + ++ + I QDLE+
Sbjct: 1217 DHLRGYIREIEATGLQT--KEELKIAHIHLKEHQETIDELRRSVSEKTAQIINT-QDLEK 1273
Query: 619 AQNEQTRELKL---KYLIIENFIPPEEKNKIMNRLFLDCEEEQWK 660
+ + E+ + + ++ N E + MN L L E+ K
Sbjct: 1274 SHTKLQEEIPVLHEEQELLPNVKEVSETQETMNELELLTEQSTTK 1318
Score = 36.2 bits (82), Expect = 0.12
Identities = 32/149 (21%), Positives = 67/149 (44%), Gaps = 8/149 (5%)
Query: 484 EEKQKL-LEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELK 542
E+K K+ LEE E+M +++ + + + A++++L + + + T E Q+ L
Sbjct: 830 EQKYKMVLEENERMNQEIVNLSKEAQKFDSSLGALKTELSYKTQELQEKTREVQERLNEM 889
Query: 543 RQEIAEQKRREREMQ---QEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVK 599
Q + + R+ +Q +E L E+ + +L QE + LK+L LQ +
Sbjct: 890 EQLKEQLENRDSTLQTVEREKTLITEKLQQTLEEVKTLTQEKD----DLKQLQESLQIER 945
Query: 600 AEIQDQHDEYIRVRQDLEEAQNEQTRELK 628
+++ + + + D +E LK
Sbjct: 946 DQLKSDIHDTVNMNIDTQEQLRNALESLK 974
Score = 34.7 bits (78), Expect = 0.36
Identities = 36/169 (21%), Positives = 77/169 (45%), Gaps = 8/169 (4%)
Query: 463 EQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLL 522
+ KE L+ +++ + + E ++ + E+ +++ E+ T+L E + L
Sbjct: 1232 QTKEELKIAHIHLKEHQETIDELRRSVSEKTAQIINTQDLEKSHTKLQEEIPVLHEEQEL 1291
Query: 523 IGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVE 582
+ + T E LEL ++ + K + EM E + L + Q+E++
Sbjct: 1292 LPNVKEVSETQETMNELELLTEQ-STTKDSTTLARIEM-----ERLRLNEKFQESQEEIK 1345
Query: 583 VKTKKLKKLYAKLQAVKAEIQDQHDEYIR-VRQDLEEAQNEQTRELKLK 630
TK+ L +A++ + DQ E+IR ++E+Q++Q + L +K
Sbjct: 1346 SLTKERDNLKTIKEALEVK-HDQLKEHIRETLAKIQESQSKQEQSLNMK 1393
Score = 33.9 bits (76), Expect = 0.61
Identities = 47/228 (20%), Positives = 101/228 (44%), Gaps = 32/228 (14%)
Query: 453 LEKNMENYLQEQKERLEEEKAAIQD---DRSLVSEEKQKLLEEKEKMLEDLRREQQATEL 509
L K + + + +E++ E+ I D D +E QK ++E +K L R ++ +
Sbjct: 1932 LSKEHKETVDKLREKISEKTIQISDIQKDLDKSKDELQKKIQELQKKELQLLRVKEDVNM 1991
Query: 510 LAAKYKAMES-KLLIGGRNI---------------MDHTNEQQKMLELKRQE---IAEQK 550
K ME K +N+ + + E+ +++ +R E I E
Sbjct: 1992 SHKKINEMEQLKKQFEAQNLSMQSVRMDNFQLTKKLHESLEEIRIVAKERDELRRIKESL 2051
Query: 551 RREREM----QQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAV---KAEIQ 603
+ ER+ +EM+ RD + +++ L + T+ L++ ++++ + +E+
Sbjct: 2052 KMERDQFIATLREMIARDRQNHQVKPEKRLLSDGQQHLTESLREKCSRIKELLKRYSEMD 2111
Query: 604 DQHDEYIRVRQDLEEAQNEQTRELKLKYLIIENFIPPEEKNKIMNRLF 651
D ++ R+ DLE+ + E +EL ++ + N P + K + +LF
Sbjct: 2112 DHYECLNRLSLDLEK-EIEFQKELSMR--VKANLSLPYLQTKHIEKLF 2156
Score = 30.0 bits (66), Expect = 8.8
Identities = 32/167 (19%), Positives = 73/167 (43%), Gaps = 17/167 (10%)
Query: 446 QPILESALEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQ 505
Q I E + KN+ + + + LE E ++ K +LL EKE ++ L+
Sbjct: 551 QLIHEISNLKNLVKHAEVYNQDLENELSS-----------KVELLREKEDQIKKLQEYID 599
Query: 506 ATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEMMLRDE 565
+ +L + ++ L +I D +Q + + + + + KR ++ E + E
Sbjct: 600 SQKL-----ENIKMDLSYSLESIEDPKQMKQTLFDAETVAL-DAKRESAFLRSENLELKE 653
Query: 566 ETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRV 612
+ EL TY ++ ++++ +L+ ++ E+Q +E ++
Sbjct: 654 KMKELATTYKQMENDIQLYQSQLEAKKKMQVDLEKELQSAFNEITKL 700
>gi|38569484 kinesin family member 21A [Homo sapiens]
Length = 1661
Score = 243 bits (621), Expect = 4e-64
Identities = 199/670 (29%), Positives = 317/670 (47%), Gaps = 108/670 (16%)
Query: 10 ALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSK 69
+++V R RP KE+ G I T VT P+ G+ K FTFD V+D S+
Sbjct: 9 SVRVAVRIRPQLAKEKIEGCH-ICT------SVTPGEPQVFLGK-DKAFTFDYVFDIDSQ 60
Query: 70 QADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTW-----VEPELRGVIPNAF 124
Q +Y + + LI+ +G+N TVFAYGQTG GKTYTM GT VE EL G+I A
Sbjct: 61 QEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTM-GTGFDVNIVEEEL-GIISRAV 118
Query: 125 EHIFTHISRSQN---------QQYLVRASYLEIYQEEI-------RDLLSKEPGKRLELK 168
+H+F I ++ + V A +LE+Y EE+ RD+ +K + +
Sbjct: 119 KHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDIDAKSKKSNIRIH 178
Query: 169 ENPETGVYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITV---- 224
E+ G+Y +++ E+ + LG +R ST MN SSRSHAIF I V
Sbjct: 179 EDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTR 238
Query: 225 ECSERGSDGQDHIRV--------------GKLNLVDLAGSERQNKAGPNTAGGAATPSSG 270
C + +D ++ K + VDLAGSER + G
Sbjct: 239 VCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTG------------- 285
Query: 271 GGGGGGGSGGGAGGERPKEASKINLSLSALGNVIAALA--GNRSTHIPYRDSKLTRLLQD 328
A GER KE IN L ALGNVI+AL R+TH+PYRDSKLTRLLQD
Sbjct: 286 -----------ATGERAKEGISINCGLLALGNVISALGDKSKRATHVPYRDSKLTRLLQD 334
Query: 329 SLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIA 388
SLGGN++TIM+A + P+ + E+L+TL++ANRA+NIKNK VN+D + + EI
Sbjct: 335 SLGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVMVNQDRASQQINALRSEIT 394
Query: 389 RLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPI 448
RL+ +L + + ++ + S + E +++ +NNN + +
Sbjct: 395 RLQMEL-----MEYKTGKRIIDEEGVESINDMFHENAMLQT-------ENNNLRVRIKAM 442
Query: 449 LES--ALEKNMENYLQEQKERL--------EEEKAAIQDDRSLVSEEKQKLLEEKEKMLE 498
E+ AL + + +Q + EE I + + + KLL E E + E
Sbjct: 443 QETVDALRSRITQLVSDQANHVLARAGEGNEEISNMIHSYIKEIEDLRAKLL-ESEAVNE 501
Query: 499 DLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQ 558
+LR+ A + + I+ E ++++L ++++ + KR+E+ ++
Sbjct: 502 NLRKNLTRATARAPYFSGSST----FSPTILSSDKETIEIIDLAKKDLEKLKRKEKRKKK 557
Query: 559 EMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLE- 617
+ +++ T T ++E V ++ +L + ++ +D+ +E D++
Sbjct: 558 SVAGKEDNT----DTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDG 613
Query: 618 -EAQNEQTRE 626
E+ +E E
Sbjct: 614 GESSDESDSE 623
Score = 39.7 bits (91), Expect = 0.011
Identities = 73/305 (23%), Positives = 120/305 (39%), Gaps = 72/305 (23%)
Query: 369 PRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPVIE 428
P + K+T+ E I K LEK +RK R+KK+V+
Sbjct: 525 PTILSSDKETI-----EIIDLAKKDLEKL-------KRKEKRKKKSVAGK---------- 562
Query: 429 AWVAEEEDDNNNNHRPPQPILE---SALEKNMENYLQEQKERLEEEKAAIQD-DRSLVSE 484
E+ D + + + + E + LE + + ++ EEE+ D D S+
Sbjct: 563 ----EDNTDTDQEKKEEKGVSERENNELEVEESQEVSDHEDEEEEEEEEEDDIDGGESSD 618
Query: 485 EKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQ 544
E +EK DL T +A K K ++ + N Q+++ LK+Q
Sbjct: 619 ESDSESDEKANYQADLAN---ITCEIAIKQKLID-----------ELENSQKRLQTLKKQ 664
Query: 545 EIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLY-AKLQAVKAEIQ 603
+ + +++ + RD+ L S++ E K KK++ Y KLQA+ E+
Sbjct: 665 YEEKLMMLQHKIRDTQLERDQVLQNL----GSVESYSEEKAKKVRSEYEKKLQAMNKEL- 719
Query: 604 DQHDEYIRVRQDLEEAQNEQTRELK--------LKYLIIENFIPPEEKNKIMNRLFLDCE 655
Q L+ AQ E R LK LK L + + +K K+ RL +
Sbjct: 720 ----------QRLQAAQKEHARLLKNQSQYEKQLKKL--QQDVMEMKKTKV--RLMKQMK 765
Query: 656 EEQWK 660
EEQ K
Sbjct: 766 EEQEK 770
>gi|7661878 kinesin family member 14 [Homo sapiens]
Length = 1648
Score = 243 bits (620), Expect = 5e-64
Identities = 154/404 (38%), Positives = 232/404 (57%), Gaps = 60/404 (14%)
Query: 13 VVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDAS----- 67
V R RP +++E+ Q++ M K ++T+ +P + + + F +YD S
Sbjct: 361 VAVRVRPFTKREKIEKASQVVFMSGK--EITVEHP-----DTKQVYNF--IYDVSFWSFD 411
Query: 68 ------SKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIP 121
+ Q +Y++ PL++ +GFN +FAYGQTG+GK+YTM G EP G+IP
Sbjct: 412 ECHPHYASQTTVYEKLAAPLLERAFEGFNTCLFAYGQTGSGKSYTMMGFSEEP---GIIP 468
Query: 122 NAFEHIFTHISRSQNQQ--YLVRASYLEIYQEEIRDLL--SKEPGKR---LELKENPETG 174
E +F+ ++R Q Q+ Y + S+ E+Y E+I DLL E G+R L ++E+P G
Sbjct: 469 RFCEDLFSQVARKQTQEVSYHIEMSFFEVYNEKIHDLLVCKDENGQRKQPLRVREHPVYG 528
Query: 175 VYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIF-IITVECSERGSDG 233
Y++ LS + + +I+ + LGN+ RA +T MN+ SSRSH++F ++ + +G
Sbjct: 529 PYVEALSMNIVSSYADIQSWLELGNKQRATAATGMNDKSSRSHSVFTLVMTQTKTEFVEG 588
Query: 234 Q--DHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEAS 291
+ DH ++NL+DLAGSER + A N G+R KE
Sbjct: 589 EEHDHRITSRINLIDLAGSERCSTAHTN------------------------GDRLKEGV 624
Query: 292 KINLSLSALGNVIAAL---AGNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHS 348
IN SL LG VI+AL A RS IPYR+S LT LL++SLGGN+KT M+AT+ PA+ +
Sbjct: 625 SINKSLLTLGKVISALSEQANQRSVFIPYRESVLTWLLKESLGGNSKTAMIATISPAASN 684
Query: 349 YDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKA 392
+E+LSTLR+AN+A+ I N +VNED L+RE + EIA+LKA
Sbjct: 685 IEETLSTLRYANQARLIVNIAKVNEDMNAKLIRELKAEIAKLKA 728
Score = 39.3 bits (90), Expect = 0.014
Identities = 35/150 (23%), Positives = 75/150 (50%), Gaps = 22/150 (14%)
Query: 481 LVSEEKQKLLEEKEKMLEDLR-REQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKML 539
L +E K+ L+ KE+M++ ++ ++ A + L+++ A ESK+ K L
Sbjct: 939 LEAEIKEAQLKAKEEMMQGIQIAKEMAQQELSSQKAAYESKI---------------KAL 983
Query: 540 ELKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVK 599
E + +E +++K+ + Q+ + EE L L+QE+ V K+L+ + A K
Sbjct: 984 EAELREESQRKKMQEINNQKANHKIEE---LEKAKQHLEQEIYVNKKRLE---METLATK 1037
Query: 600 AEIQDQHDEYIRVRQDLEEAQNEQTRELKL 629
++D + R+ + LE + + +E+++
Sbjct: 1038 QALEDHSIRHARILEALETEKQKIAKEVQI 1067
Score = 34.3 bits (77), Expect = 0.46
Identities = 63/326 (19%), Positives = 138/326 (42%), Gaps = 55/326 (16%)
Query: 376 KDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEE 435
+DT + E ++ K +L ++ +R + ++ ++ + A +G I +A++E
Sbjct: 913 RDTPISEGPKDFEFAKNEL----LMAQRSQLEAEIKEAQLKAKEEMMQGIQIAKEMAQQE 968
Query: 436 DDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRSLVSEEKQKLLEEKEK 495
+ + ES + K +E L+E+ +R + ++ + +++ +EE EK
Sbjct: 969 LSSQ------KAAYESKI-KALEAELREESQRKKMQE--------INNQKANHKIEELEK 1013
Query: 496 MLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRRERE 555
+ L +E + K +E + L + + DH+ ++LE E + + +
Sbjct: 1014 AKQHLEQE------IYVNKKRLEMETLATKQALEDHSIRHARILEALETEKQKIAKEVQI 1067
Query: 556 MQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQD 615
+QQ RD +T ++ T++S+ KL + + A+ ++++ Y+ R D
Sbjct: 1068 LQQNRNNRD-KTFTVQTTWSSM---------KLSMMIQEANAISSKLKTY---YVFGRHD 1114
Query: 616 LEEAQNEQT----RELKLKYLIIENFIPPEEKNKIMNRLFLD----------CE-EEQWK 660
+ + + T R LKL + E K M L+ C+ E++W
Sbjct: 1115 ISDKSSSDTSIRVRNLKLGISTFWSLEKFESKLAAMKELYESNGSNRGEDAFCDPEDEW- 1173
Query: 661 FQPLVPAGVSSSQMKKRPTSAVGYKR 686
+P + SS ++R S + +R
Sbjct: 1174 -EPDITDAPVSSLSRRRSRSLMKNRR 1198
>gi|4758648 kinesin family member 5B [Homo sapiens]
Length = 963
Score = 241 bits (615), Expect = 2e-63
Identities = 183/597 (30%), Positives = 292/597 (48%), Gaps = 72/597 (12%)
Query: 11 LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSKQ 70
+KV+ R RPL+ E G + I + V P + FD V+ +S+ Q
Sbjct: 9 IKVMCRFRPLNESEVNRGDKYIAKFQGEDTVVIASKP----------YAFDRVFQSSTSQ 58
Query: 71 ADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEHIFTH 130
+Y++ + ++ VL+G+NGT+FAYGQT +GKT+TM+G +PE G+IP + IF +
Sbjct: 59 EQVYNDCAKKIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPEGMGIIPRIVQDIFNY 118
Query: 131 I-SRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVTKNVK 189
I S +N ++ ++ SY EIY ++IRDLL L + E+ Y+K + +
Sbjct: 119 IYSMDENLEFHIKVSYFEIYLDKIRDLLDVSK-TNLSVHEDKNRVPYVKGCTERFVCSPD 177
Query: 190 EIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKLNLVDLAG 249
E+ ++ G R V T+MNE SSRSH+IF+I V+ ++ + GKL LVDLAG
Sbjct: 178 EVMDTIDEGKSNRHVAVTNMNEHSSRSHSIFLINVKQENTQTEQK---LSGKLYLVDLAG 234
Query: 250 SERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGNVIAALAG 309
SE+ +K GA G EA IN SLSALGNVI+ALA
Sbjct: 235 SEKVSKT------------------------GAEGAVLDEAKNINKSLSALGNVISALA- 269
Query: 310 NRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKP 369
ST++PYRDSK+TR+LQDSLGGN +T +V P+S++ E+ STL F RAK IKN
Sbjct: 270 EGSTYVPYRDSKMTRILQDSLGGNCRTTIVICCSPSSYNESETKSTLLFGQRAKTIKNTV 329
Query: 370 RVN-EDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGY-PEGPVI 427
VN E + +++++E + K ++ + + R + V + E +
Sbjct: 330 CVNVELTAEQWKKKYEKE--KEKNKILRNTIQWLENELNRWRNGETVPIDEQFDKEKANL 387
Query: 428 EAWVAEEEDDNNNNHRPPQPI-----LESALEKNMENYLQEQKERLEEEKAAIQDDRSLV 482
EA+ ++D N +P I A + E + + ++L+++ I LV
Sbjct: 388 EAFTV-DKDITLTNDKPATAIGVIGNFTDAERRKCEEEIAKLYKQLDDKDEEINQQSQLV 446
Query: 483 SEEKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELK 542
+ K ++L++ E++L RR+Q N+ N Q +
Sbjct: 447 EKLKTQMLDQ-EELLASTRRDQD---------------------NMQAELNRLQAENDAS 484
Query: 543 RQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVK 599
++E+ E + E+ + +E + Y L E+ K+ L + A+LQ +K
Sbjct: 485 KEEVKEVLQALEELAVNYDQKSQEVEDKTKEYELLSDELNQKSATLASIDAELQKLK 541
Score = 45.8 bits (107), Expect = 2e-04
Identities = 52/190 (27%), Positives = 90/190 (47%), Gaps = 35/190 (18%)
Query: 455 KNMENYLQ--EQKER-LEEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLA 511
K++ YLQ EQK+R LEE A+ ++ LV Q+ + E EK E L + Q A E+
Sbjct: 644 KSLTEYLQNVEQKKRQLEESVDALSEE--LVQLRAQEKVHEMEK--EHLNKVQTANEVKQ 699
Query: 512 AKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQ---QEMMLRDEETM 568
A + ++S H QK + R E+ + + ++Q Q+MML E
Sbjct: 700 AVEQQIQS-----------HRETHQKQISSLRDEVEAKAKLITDLQDQNQKMMLEQER-- 746
Query: 569 ELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTRELK 628
LR + L+ + K++KL +L +QD+ ++ RQDL+ + +EL+
Sbjct: 747 -LRVEHEKLKATDQEKSRKLHELTV--------MQDRREQ---ARQDLKGLEETVAKELQ 794
Query: 629 LKYLIIENFI 638
+ + + F+
Sbjct: 795 TLHNLRKLFV 804
>gi|148612831 kinesin family member 18A [Homo sapiens]
Length = 898
Score = 239 bits (609), Expect = 1e-62
Identities = 198/640 (30%), Positives = 324/640 (50%), Gaps = 108/640 (16%)
Query: 11 LKVVARCRPLSRKEEAAGHEQ--------ILTMDVKLGQVTLRNPRAAPGE-------LP 55
+KVV R RP + KE+AAG + IL D K +V+ + + +
Sbjct: 12 MKVVVRVRPENTKEKAAGFHKVVHVVDKHILVFDPKQEEVSFFHGKKTTNQNVIKKQNKD 71
Query: 56 KTFTFDAVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPE 115
F FDAV+D +S Q+++++ T +P++ S L G+N TV AYG TG GKT+TM G+ EP
Sbjct: 72 LKFVFDAVFDETSTQSEVFEHTTKPILRSFLNGYNCTVLAYGATGAGKTHTMLGSADEP- 130
Query: 116 LRGVIPNAFEHIFTHISRSQNQQYLVRA-SYLEIYQEEIRDLLSKEPGKRLELKENPETG 174
GV+ H++ + + ++ A SYLE+Y E+IRDLL L ++E+ + G
Sbjct: 131 --GVMYLTMLHLYKCMDEIKEEKICSTAVSYLEVYNEQIRDLLVNSGP--LAVREDTQKG 186
Query: 175 VYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQ 234
V + L+ K+ +EI H+++ GN+ R T MN SSRSHA+F I + ++ +
Sbjct: 187 VVVHGLTLHQPKSSEEILHLLDNGNKNRTQHPTDMNATSSRSHAVFQIYLRQQDKTASIN 246
Query: 235 DHIRVGKLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKIN 294
++R+ K++L+DLAGSER S GA G R E + IN
Sbjct: 247 QNVRIAKMSLIDLAGSER------------------------ASTSGAKGTRFVEGTNIN 282
Query: 295 LSLSALGNVIAALAGNR--STHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDES 352
SL ALGNVI ALA ++ + HIPYR+SKLTRLL+DSLGGN +TIM+A + P+S YD++
Sbjct: 283 RSLLALGNVINALADSKRKNQHIPYRNSKLTRLLKDSLGGNCQTIMIAAVSPSSVFYDDT 342
Query: 353 LSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRK 412
+TL++ANRAK+IK+ + N + + ++ + KA++ L + + K+ +
Sbjct: 343 YNTLKYANRAKDIKSSLKSNVLNVNNHITQYVKICNEQKAEI-----LLLKEKLKAYEEQ 397
Query: 413 KAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEK 472
KA + N N+ + + N +++ ER +E
Sbjct: 398 KAFT---------------------NENDQ----------AKLMISNPQEKEIERFQEIL 426
Query: 473 AAIQDDRSLVSEEKQKL-LEEKEKMLEDLRREQ--QATELLAAKYKAMESKLLIGGRNIM 529
+ +R + +E KL + KE L+ ++Q + E++ ++ K ++ G R
Sbjct: 427 NCLFQNREEIRQEYLKLEMLLKENELKSFYQQQCHKQIEMMCSEDKVEKA---TGKR--- 480
Query: 530 DHTNEQQKMLELKRQEIAEQKRREREMQQ-----EMMLRDEETMELRGTYTSLQQEVEVK 584
DH ++ LK + +KRRE E++Q + R E+ M L + +E++ K
Sbjct: 481 DH-----RLAMLKTRRSYLEKRREEELKQFDENTNWLHRVEKEMGLLSQNGHIPKELK-K 534
Query: 585 TKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQT 624
L+ + + +KA+I+ D L+E Q+ QT
Sbjct: 535 DLHCHHLHLQNKDLKAQIRHMMD-----LACLQEQQHRQT 569
>gi|83716024 kinesin family member 21B [Homo sapiens]
Length = 1624
Score = 238 bits (608), Expect = 1e-62
Identities = 207/683 (30%), Positives = 316/683 (46%), Gaps = 113/683 (16%)
Query: 11 LKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSKQ 70
+KV R RP KE+ G I T VT P+ G+ K FT+D V+D + Q
Sbjct: 9 VKVAVRIRPQLSKEKIEGCH-ICT------SVTPGEPQVLLGK-DKAFTYDFVFDLDTWQ 60
Query: 71 ADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVE----PELRGVIPNAFEH 126
+Y V LI+ +G+N TV AYGQTG GKTYTM GT + E +G+IP A H
Sbjct: 61 EQIYSTCVSKLIEGCFEGYNATVLAYGQTGAGKTYTM-GTGFDMATSEEEQGIIPRAIAH 119
Query: 127 IFTHIS----RSQNQ-----QYLVRASYLEIYQEEIRDLL--SKEPGKR-----LELKEN 170
+F I+ R+Q Q ++ V A +LE+Y EEI DL +++P R +++ E+
Sbjct: 120 LFGGIAERKRRAQEQGVAGPEFKVSAQFLELYNEEILDLFDSTRDPDTRHRRSNIKIHED 179
Query: 171 PETGVYIKDLSSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERG 230
G+Y ++S + + +E+ + G +R ST MN SSRSHAIF I + C R
Sbjct: 180 ANGGIYTTGVTSRLIHSQEELIQCLKQGALSRTTASTQMNVQSSRSHAIFTIHL-CQMRM 238
Query: 231 SDGQDHIR-------------------VGKLNLVDLAGSERQNKAGPNTAGGAATPSSGG 271
D + K + VDLAGSER + G
Sbjct: 239 CTQPDLVNEAVTGLPDGTPPSSEYETLTAKFHFVDLAGSERLKRTG-------------- 284
Query: 272 GGGGGGSGGGAGGERPKEASKINLSLSALGNVIAALA--GNRSTHIPYRDSKLTRLLQDS 329
A GER KE IN L ALGNVI+AL + H+PYRDSKLTRLLQDS
Sbjct: 285 ----------ATGERAKEGISINCGLLALGNVISALGDQSKKVVHVPYRDSKLTRLLQDS 334
Query: 330 LGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNKPRVNEDPKDTLLREFQEEIAR 389
LGGN++TIM+A + P+ + E+L+TL++ANRA+NIKNK VN+D + + EIAR
Sbjct: 335 LGGNSQTIMIACVSPSDRDFMETLNTLKYANRARNIKNKVVVNQDKTSQQISALRAEIAR 394
Query: 390 LKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPIL 449
L+ +L + K+ +R GY + A + +E + Q +
Sbjct: 395 LQMELME---------YKAGKRVIGEDGAEGYSDLFRENAMLQKENGALRLRVKAMQEAI 445
Query: 450 ESALEKNMENYLQEQKERL---------EEEKAAIQDDRSLVSEEKQKLLEEKEKMLEDL 500
++ N L Q+ L E A IQ+ + E + KLL E E M E L
Sbjct: 446 DAI--NNRVTQLMSQEANLLLAKAGDGNEAIGALIQNYIREIEELRTKLL-ESEAMNESL 502
Query: 501 RREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKRREREMQQEM 560
RR + G + + +++ +Q++ ++ +++E++Q
Sbjct: 503 RRSLSRASARSPYSLGASPAAPAFGGSPASSMEDASEVIRRAKQDL--ERLKKKEVRQRR 560
Query: 561 MLRDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQ 620
++E + R LQQE +T + E +++ +E + EE +
Sbjct: 561 KSPEKEAFKKR---AKLQQENSEETD------------ENEAEEEEEERDESGCEEEEGR 605
Query: 621 NEQTRELKLKYLIIENFIPPEEK 643
++ + + ++++ PEEK
Sbjct: 606 EDEDEDSGSEESLVDSDSDPEEK 628
Score = 32.7 bits (73), Expect = 1.4
Identities = 35/142 (24%), Positives = 70/142 (49%), Gaps = 20/142 (14%)
Query: 457 MENYLQEQKERLEE--EKAAIQDDRSLVSEEKQKLLEEKEKMLEDLRREQQATELLAAKY 514
ME Y +E+ +++ EK + +R L ++ Q +E ++L++ R ++ + L A+
Sbjct: 695 MECYTEEKANKIKADYEKRLREMNRDL--QKLQAAQKEHARLLKNQSRYERELKKLQAEV 752
Query: 515 KAMESKLLIGGRNIMDHTNEQQKMLELKR-QEIAEQKRRER------------EMQQEMM 561
M+ K + M ++++++E KR +EIA+ K+ +R + QQEM+
Sbjct: 753 AEMK-KAKVALMKQMREEQQRRRLVETKRNREIAQLKKEQRRQEFQIRALESQKRQQEMV 811
Query: 562 LR--DEETMELRGTYTSLQQEV 581
LR +E LR + + V
Sbjct: 812 LRRKTQEVSALRRLAKPMSERV 833
>gi|4758650 kinesin family member 5C [Homo sapiens]
Length = 957
Score = 238 bits (607), Expect = 2e-62
Identities = 187/593 (31%), Positives = 292/593 (49%), Gaps = 66/593 (11%)
Query: 10 ALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGELPKTFTFDAVYDASSK 69
++KV+ R RPL+ E G + I G T+ + P + FD V ++
Sbjct: 8 SIKVMCRFRPLNEAEILRGDKFIPKFK---GDETVVIGQGKP------YVFDRVLPPNTT 58
Query: 70 QADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIPNAFEHIFT 129
Q +Y+ + ++ VL+G+NGT+FAYGQT +GKT+TM+G +P+L G+IP IF
Sbjct: 59 QEQVYNACAKQIVKDVLEGYNGTIFAYGQTSSGKTHTMEGKLHDPQLMGIIPRIAHDIFD 118
Query: 130 HI-SRSQNQQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDLSSFVTKNV 188
HI S +N ++ ++ SY EIY ++IRDLL L + E+ Y+K + +
Sbjct: 119 HIYSMDENLEFHIKVSYFEIYLDKIRDLLDVSK-TNLAVHEDKNRVPYVKGCTERFVSSP 177
Query: 189 KEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVGKLNLVDLA 248
+E+ V++ G R V T+MNE SSRSH+IF+I ++ ++ + GKL LVDLA
Sbjct: 178 EEVMDVIDEGKANRHVAVTNMNEHSSRSHSIFLINIKQENVETEKK---LSGKLYLVDLA 234
Query: 249 GSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSALGNVIAALA 308
GSE+ +K G A G EA IN SLSALGNVI+ALA
Sbjct: 235 GSEKVSKTG------------------------AEGAVLDEAKNINKSLSALGNVISALA 270
Query: 309 GNRSTHIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFANRAKNIKNK 368
TH+PYRDSK+TR+LQDSLGGN +T +V P+ + E+ STL F RAK IKN
Sbjct: 271 EGTKTHVPYRDSKMTRILQDSLGGNCRTTIVICCSPSVFNEAETKSTLMFGQRAKTIKNT 330
Query: 369 PRVN-EDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYPEGPVI 427
VN E + +++++E + K + K + R +AV PE I
Sbjct: 331 VSVNLELTAEEWKKKYEKE--KEKNKTLKNVIQHLEMELNRWRNGEAV------PEDEQI 382
Query: 428 EAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQ---DDRSLVSE 484
A +D N PI+++ + + E+KE+ +EE +++ DD+
Sbjct: 383 SA-----KDQKNLEPCDNTPIIDN-IAPVVAGISTEEKEKYDEEISSLYRQLDDKDDEIN 436
Query: 485 EKQKLLEEKEKMLEDLRREQQATELLAAKYKAMESKLLIGGRNIMDHTNEQQKMLE---- 540
++ +L E+ ++ + D +T K + ++L I D E + LE
Sbjct: 437 QQSQLAEKLKQQMLDQDELLASTRRDYEKIQEELTRLQIENEAAKDEVKEVLQALEELAV 496
Query: 541 ---LKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQEVEVKTKKLKK 590
K QE+ ++ R ++ E+ ++T L T L Q E+ + K+
Sbjct: 497 NYDQKSQEVEDKTRANEQLTDELA---QKTTTLTTTQRELSQLQELSNHQKKR 546
Score = 52.8 bits (125), Expect = 1e-06
Identities = 52/191 (27%), Positives = 93/191 (48%), Gaps = 32/191 (16%)
Query: 455 KNMENYLQ--EQKER-LEEEKAAIQDDRS-LVSEEKQKLLEEKEKMLEDLRREQQATELL 510
K++ +Y+Q EQK R LEE + ++ ++ + L ++EK + ++K E L R Q A E+
Sbjct: 641 KSLTDYMQNMEQKRRQLEESQDSLSEELAKLRAQEKMHEVSFQDKEKEHLTRLQDAEEMK 700
Query: 511 AAKYKAMESKLLIGGRNIMDHTNEQQKMLELKRQEIAEQKR---REREMQQEMMLRDEET 567
A + MES H QK L R EI E+++ R++ Q++ L E
Sbjct: 701 KALEQQMES-----------HREAHQKQLSRLRDEIEEKQKIIDEIRDLNQKLQLEQE-- 747
Query: 568 MELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEAQNEQTREL 627
+L Y L+ E + + KL+KL +D+ + R+DL+ + +REL
Sbjct: 748 -KLSSDYNKLKIEDQEREMKLEKLLL-----------LNDKREQAREDLKGLEETVSREL 795
Query: 628 KLKYLIIENFI 638
+ + + + F+
Sbjct: 796 QTLHNLRKLFV 806
Score = 38.9 bits (89), Expect = 0.019
Identities = 62/297 (20%), Positives = 123/297 (41%), Gaps = 77/297 (25%)
Query: 363 KNIKNKPRVNEDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRKKAVSAPPGYP 422
+N++ K R E+ +D+L EE+A+L+AQ EK + + + K
Sbjct: 648 QNMEQKRRQLEESQDSL----SEELAKLRAQ-EKMHEVSFQDKEKEH------------- 689
Query: 423 EGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEKAAIQDDRSLV 482
+ AEE ++ ALE+ ME++ + +++L + I++ + ++
Sbjct: 690 ---LTRLQDAEE--------------MKKALEQQMESHREAHQKQLSRLRDEIEEKQKII 732
Query: 483 SEEK---QKLLEEKEKM--------LEDLRREQQATELLAAKYKAMESKLLIGGRN---- 527
E + QKL E+EK+ +ED RE + +LL K +++ + G
Sbjct: 733 DEIRDLNQKLQLEQEKLSSDYNKLKIEDQEREMKLEKLLLLNDKREQAREDLKGLEETVS 792
Query: 528 -------------IMDHTNEQQKMLELKRQE---IAEQKRR----EREMQQ-----EMML 562
+ D T +K +EL + A QK++ E ++Q + ++
Sbjct: 793 RELQTLHNLRKLFVQDLTTRVKKSVELDNDDGGGSAAQKQKISFLENNLEQLTKVHKQLV 852
Query: 563 RDEETMELRGTYTSLQQEVEVKTKKLKKLYAKLQAVKAEIQDQHDEYIRVRQDLEEA 619
RD +LR L++ + +++K L + L+ K Y + ++EA
Sbjct: 853 RD--NADLRCELPKLEKRLRATAERVKALESALKEAKENAMRDRKRYQQEVDRIKEA 907
>gi|156616271 kinesin family member 19 [Homo sapiens]
Length = 998
Score = 234 bits (596), Expect = 3e-61
Identities = 187/597 (31%), Positives = 292/597 (48%), Gaps = 84/597 (14%)
Query: 9 EALKVVARCRPLSRKEEAAGHEQILTMDVKLGQVTLRNPRAAPGEL-------PKTFTFD 61
+ L V R RP+S E G ++ V V L +P P ++ K++ FD
Sbjct: 10 QQLMVALRVRPISVAELEEG-ATLIAHKVDEQMVVLMDPMEDPDDILRAHRSREKSYLFD 68
Query: 62 AVYDASSKQADLYDETVRPLIDSVLQGFNGTVFAYGQTGTGKTYTMQGTWVEPELRGVIP 121
+D ++ Q +Y T + LI+ V+ G+N TVFAYG TG GKTYTM GT EP G+
Sbjct: 69 VAFDFTATQEMVYQATTKSLIEGVISGYNATVFAYGPTGCGKTYTMLGTDQEP---GIYV 125
Query: 122 NAFEHIFTHISRSQN-QQYLVRASYLEIYQEEIRDLLSKEPGKRLELKENPETGVYIKDL 180
+F I + N +Y V SYLEIY E IRDLL+ G LEL+E+ + + + +
Sbjct: 126 QTLNDLFRAIEETSNDMEYEVSMSYLEIYNEMIRDLLNPSLG-YLELREDSKGVIQVAGI 184
Query: 181 SSFVTKNVKEIEHVMNLGNQTRAVGSTHMNEVSSRSHAIFIITVECSERGSDGQDHIRVG 240
+ T N KEI ++ GN+ R T N+ SSRSHA+ +TV R + +R G
Sbjct: 185 TEVSTINAKEIMQLLMKGNRQRTQEPTAANQTSSRSHAVLQVTVRQRSRVKNILQEVRQG 244
Query: 241 KLNLVDLAGSERQNKAGPNTAGGAATPSSGGGGGGGGSGGGAGGERPKEASKINLSLSAL 300
+L ++DLAGSER ++ G+R KE + IN SL AL
Sbjct: 245 RLFMIDLAGSERASQTQNR------------------------GQRMKEGAHINRSLLAL 280
Query: 301 GNVIAALAGNRST-HIPYRDSKLTRLLQDSLGGNAKTIMVATLGPASHSYDESLSTLRFA 359
GN I AL+ S +I YRDSKLTRLL+DSLGGN++T+M+A + PAS +++ES +TL +A
Sbjct: 281 GNCINALSDKGSNKYINYRDSKLTRLLKDSLGGNSRTVMIAHISPASSAFEESRNTLTYA 340
Query: 360 NRAKNIKNKPRVN-------EDPKDTLLREFQEEIARLKAQLEKRGMLGKRPRRKSSRRK 412
RAKNIK + + N +++ + + EI RLK +++++ G+ R+
Sbjct: 341 GRAKNIKTRVKQNLLNVSYHIAQYTSIIADLRGEIQRLKRKIDEQTGRGQARGRQDRGDI 400
Query: 413 KAVSAPPGYPEGPVIEAWVAEEEDDNNNNHRPPQPILESALEKNMENYLQEQKERLEEEK 472
+ + A G +A + + + L SA ++ M+ ++ + LE
Sbjct: 401 RHIQAEVQLHSGQGEKAGMGQLREQ-----------LASAFQEQMD--VRRRLLELENRA 447
Query: 473 AAIQDDRSLVSEEKQKLLE----EKEKMLEDLR-REQQATELLAAKYKAMESKLLIGGRN 527
+Q D S + LL + EK L+ RE+Q E A +S
Sbjct: 448 MEVQIDTS------RHLLTIAGWKHEKSRRALKWREEQRKECYAKDDSEKDS-------- 493
Query: 528 IMDHTNEQQKMLE-----LKRQEIAEQKRREREMQQEMMLRDEETMELRGTYTSLQQ 579
D ++Q +LE R+ IA +++++++ + ++ ELR L++
Sbjct: 494 --DTGDDQPDILEPPEVAAARESIAALVDEQKQLRKQKLALEQRCRELRARGRRLEE 548
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.129 0.356
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 31,013,641
Number of Sequences: 37866
Number of extensions: 1544044
Number of successful extensions: 30964
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 680
Number of HSP's successfully gapped in prelim test: 1061
Number of HSP's that attempted gapping in prelim test: 13591
Number of HSP's gapped (non-prelim): 9301
length of query: 793
length of database: 18,247,518
effective HSP length: 110
effective length of query: 683
effective length of database: 14,082,258
effective search space: 9618182214
effective search space used: 9618182214
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Home |
Table of Contents |
Search text |
Search genes |
Search sequences |
Purchase |
FAQ |
Blog |
Help
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.