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Search of human proteins with 41152114
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|41152114 aldo-keto reductase family 7, member A3 [Homo
sapiens]
(331 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens] 684 0.0
gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo s... 633 0.0
gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens] 601 e-172
gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo s... 318 3e-87
gi|4504825 potassium voltage-gated channel, shaker-related subfa... 83 3e-16
gi|27436969 potassium voltage-gated channel, shaker-related subf... 83 3e-16
gi|27436964 potassium voltage-gated channel, shaker-related subf... 81 1e-15
gi|27436962 potassium voltage-gated channel, shaker-related subf... 81 1e-15
gi|27436966 potassium voltage-gated channel, shaker-related subf... 81 1e-15
gi|27436971 potassium voltage-gated channel, shaker-related subf... 70 2e-12
gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens] 53 4e-07
gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens] 52 6e-07
gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens] 52 6e-07
gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens] 50 2e-06
gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens] 46 5e-05
gi|207028673 hypothetical protein LOC100134257 [Homo sapiens] 44 2e-04
gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens] 33 0.27
gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens] 33 0.27
gi|71999153 hypothetical protein LOC23334 [Homo sapiens] 30 2.3
gi|219555718 synaptonemal complex central element protein 1 isof... 30 3.0
gi|219555716 synaptonemal complex central element protein 1 isof... 30 3.0
gi|18640754 synaptonemal complex central element protein 1 isofo... 30 3.0
gi|225690604 alpha-synuclein isoform NACP140 [Homo sapiens] 29 5.1
gi|225690602 alpha-synuclein isoform NACP140 [Homo sapiens] 29 5.1
gi|4507109 alpha-synuclein isoform NACP140 [Homo sapiens] 29 5.1
>gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens]
Length = 331
Score = 684 bits (1765), Expect = 0.0
Identities = 331/331 (100%), Positives = 331/331 (100%)
Query: 1 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGG 60
MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGG
Sbjct: 1 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGG 60
Query: 61 LGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP 120
LGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP
Sbjct: 61 LGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP 120
Query: 121 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE 180
VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE
Sbjct: 121 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE 180
Query: 181 TELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEH 240
TELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEH
Sbjct: 181 TELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEH 240
Query: 241 HFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLA 300
HFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLA
Sbjct: 241 HFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLA 300
Query: 301 AAEEGPLEPAVVDAFNQAWHLVTHECPNYFR 331
AAEEGPLEPAVVDAFNQAWHLVTHECPNYFR
Sbjct: 301 AAEEGPLEPAVVDAFNQAWHLVTHECPNYFR 331
>gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo
sapiens]
Length = 331
Score = 633 bits (1633), Expect = 0.0
Identities = 305/330 (92%), Positives = 314/330 (95%)
Query: 1 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGG 60
MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAF+YS+GQSETILGG
Sbjct: 1 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGG 60
Query: 61 LGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP 120
LGLR+G SDCRVKI TKA P GNSLKPDS+R QLETSLKRLQCP VDLFYLH PDHS P
Sbjct: 61 LGLRMGSSDCRVKIATKANPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAP 120
Query: 121 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVE 180
VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMY+A TRQVE
Sbjct: 121 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYSATTRQVE 180
Query: 181 TELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEH 240
TELFPCLRHFGLRFYA+NPLAGGLLTGKYKYEDK+GKQPVGRFFG WAE+YRN +WKEH
Sbjct: 181 TELFPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGTQWAEIYRNHFWKEH 240
Query: 241 HFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLA 300
HFEGIALVEKALQAAYGASAPSMTSA LRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLA
Sbjct: 241 HFEGIALVEKALQAAYGASAPSMTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLA 300
Query: 301 AAEEGPLEPAVVDAFNQAWHLVTHECPNYF 330
AAEEGPLEPAVVDAFNQAWHL HECPNYF
Sbjct: 301 AAEEGPLEPAVVDAFNQAWHLFAHECPNYF 330
>gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens]
Length = 359
Score = 601 bits (1550), Expect = e-172
Identities = 290/335 (86%), Positives = 306/335 (91%), Gaps = 5/335 (1%)
Query: 2 SRQLSRARP-----ATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSET 56
+R L+ +RP A+VLG MEMGRRMDAP SAA RAFLERGHTE+DTAF+YS+GQSET
Sbjct: 25 ARALAMSRPPPPRVASVLGTMEMGRRMDAPASAAAVRAFLERGHTELDTAFMYSDGQSET 84
Query: 57 ILGGLGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPD 116
ILGGLGL LGG DCRVKI TKA P G SLKPDS+R QLETSLKRLQCP+VDLFYLH PD
Sbjct: 85 ILGGLGLGLGGGDCRVKIATKANPWDGKSLKPDSVRSQLETSLKRLQCPQVDLFYLHAPD 144
Query: 117 HSTPVEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAIT 176
H TPVEETL AC +LHQEGKFVELGLSNYA+WEVAEICTLCKSNGWILPTVYQGMYNA T
Sbjct: 145 HGTPVEETLHACQRLHQEGKFVELGLSNYASWEVAEICTLCKSNGWILPTVYQGMYNATT 204
Query: 177 RQVETELFPCLRHFGLRFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRY 236
RQVETELFPCLRHFGLRFYA+NPLAGGLLTGKYKYEDK+GKQPVGRFFGN+WAE YRNR+
Sbjct: 205 RQVETELFPCLRHFGLRFYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGNSWAETYRNRF 264
Query: 237 WKEHHFEGIALVEKALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLE 296
WKEHHFE IALVEKALQAAYGASAPS+TSA LRWMYHHSQLQGAHGDAVILGMSSLEQLE
Sbjct: 265 WKEHHFEAIALVEKALQAAYGASAPSVTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLE 324
Query: 297 QNLAAAEEGPLEPAVVDAFNQAWHLVTHECPNYFR 331
QNLAA EEGPLEPAVVDAFNQAWHLV HECPNYFR
Sbjct: 325 QNLAATEEGPLEPAVVDAFNQAWHLVAHECPNYFR 359
>gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo
sapiens]
Length = 249
Score = 318 bits (816), Expect = 3e-87
Identities = 158/177 (89%), Positives = 163/177 (92%)
Query: 1 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGG 60
MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAF+YS+GQSETILGG
Sbjct: 1 MSRQLSRARPATVLGAMEMGRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGG 60
Query: 61 LGLRLGGSDCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTP 120
LGLR+G SDCRVKI TKA P GNSLKPDS+R QLETSLKRLQCP VDLFYLH PDHS P
Sbjct: 61 LGLRMGSSDCRVKIATKANPWIGNSLKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAP 120
Query: 121 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITR 177
VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQ + A R
Sbjct: 121 VEETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQLLEGAPLR 177
>gi|4504825 potassium voltage-gated channel, shaker-related
subfamily, beta member 2 isoform 1 [Homo sapiens]
Length = 367
Score = 83.2 bits (204), Expect = 3e-16
Identities = 78/296 (26%), Positives = 136/296 (45%), Gaps = 25/296 (8%)
Query: 20 GRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAI 79
G+ D +T A+ + G DTA VY+ G++E +LG + + G + I TK
Sbjct: 62 GQITDEMAEQLMTLAY-DNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIF 120
Query: 80 PLFGNSLKPDS------LRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQ 133
+G + + + L+ SL+RLQ VD+ + + PD +TP+EET+RA +
Sbjct: 121 --WGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVIN 178
Query: 134 EGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQ-VETELFPCLRHFGL 192
+G + G S +++ E+ E ++ + P Q Y+ R+ VE +L G+
Sbjct: 179 QGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELFHKIGV 238
Query: 193 RFYAFNPLAGGLLTGKYKYEDKNGKQPVGR--FFGNTWAEMYRNRYWKEHHFEGIALVEK 250
++PLA G+++GKY +G P R G W +++ E A + K
Sbjct: 239 GAMTWSPLACGIVSGKY----DSGIPPYSRASLKGYQW---LKDKILSEEGRRQQAKL-K 290
Query: 251 ALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGP 306
LQA ++ + W L+ +V+LG S+ +QL +N+ A + P
Sbjct: 291 ELQAIAERLGCTLPQLAIAWC-----LRNEGVSSVLLGASNADQLMENIGAIQVLP 341
>gi|27436969 potassium voltage-gated channel, shaker-related
subfamily, beta member 2 isoform 2 [Homo sapiens]
Length = 353
Score = 83.2 bits (204), Expect = 3e-16
Identities = 78/296 (26%), Positives = 136/296 (45%), Gaps = 25/296 (8%)
Query: 20 GRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAI 79
G+ D +T A+ + G DTA VY+ G++E +LG + + G + I TK
Sbjct: 48 GQITDEMAEQLMTLAY-DNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIF 106
Query: 80 PLFGNSLKPDS------LRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQ 133
+G + + + L+ SL+RLQ VD+ + + PD +TP+EET+RA +
Sbjct: 107 --WGGKAETERGLSRKHIIEGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVIN 164
Query: 134 EGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQ-VETELFPCLRHFGL 192
+G + G S +++ E+ E ++ + P Q Y+ R+ VE +L G+
Sbjct: 165 QGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELFHKIGV 224
Query: 193 RFYAFNPLAGGLLTGKYKYEDKNGKQPVGR--FFGNTWAEMYRNRYWKEHHFEGIALVEK 250
++PLA G+++GKY +G P R G W +++ E A + K
Sbjct: 225 GAMTWSPLACGIVSGKY----DSGIPPYSRASLKGYQW---LKDKILSEEGRRQQAKL-K 276
Query: 251 ALQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGP 306
LQA ++ + W L+ +V+LG S+ +QL +N+ A + P
Sbjct: 277 ELQAIAERLGCTLPQLAIAWC-----LRNEGVSSVLLGASNADQLMENIGAIQVLP 327
>gi|27436964 potassium voltage-gated channel, shaker-related
subfamily, beta member 1 isoform 3 [Homo sapiens]
Length = 401
Score = 80.9 bits (198), Expect = 1e-15
Identities = 80/295 (27%), Positives = 133/295 (45%), Gaps = 23/295 (7%)
Query: 20 GRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAI 79
G+ D +T A+ E G DTA VY+ G++E ILG + + G + I TK
Sbjct: 96 GQISDEVAERLMTIAY-ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY 154
Query: 80 PLFGNSLKPDS------LRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQ 133
+G + + + L+ SL+RLQ VD+ + + PD +TP+EE +RA +
Sbjct: 155 --WGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVIN 212
Query: 134 EGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQ-VETELFPCLRHFGL 192
+G + G S ++A E+ E ++ + I P Q Y+ R+ VE +L G+
Sbjct: 213 QGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGV 272
Query: 193 RFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVE-KA 251
++PLA G+++GKY NG R + + +E + L +
Sbjct: 273 GAMTWSPLACGIISGKY----GNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSP 328
Query: 252 LQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGP 306
+ G + P + A W L+ +V+LG S+ EQL +NL A + P
Sbjct: 329 IAERLGCTLPQLAVA---WC-----LRNEGVSSVLLGSSTPEQLIENLGAIQVLP 375
>gi|27436962 potassium voltage-gated channel, shaker-related
subfamily, beta member 1 isoform 2 [Homo sapiens]
Length = 408
Score = 80.9 bits (198), Expect = 1e-15
Identities = 80/295 (27%), Positives = 133/295 (45%), Gaps = 23/295 (7%)
Query: 20 GRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAI 79
G+ D +T A+ E G DTA VY+ G++E ILG + + G + I TK
Sbjct: 103 GQISDEVAERLMTIAY-ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY 161
Query: 80 PLFGNSLKPDS------LRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQ 133
+G + + + L+ SL+RLQ VD+ + + PD +TP+EE +RA +
Sbjct: 162 --WGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVIN 219
Query: 134 EGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQ-VETELFPCLRHFGL 192
+G + G S ++A E+ E ++ + I P Q Y+ R+ VE +L G+
Sbjct: 220 QGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGV 279
Query: 193 RFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVE-KA 251
++PLA G+++GKY NG R + + +E + L +
Sbjct: 280 GAMTWSPLACGIISGKY----GNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSP 335
Query: 252 LQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGP 306
+ G + P + A W L+ +V+LG S+ EQL +NL A + P
Sbjct: 336 IAERLGCTLPQLAVA---WC-----LRNEGVSSVLLGSSTPEQLIENLGAIQVLP 382
>gi|27436966 potassium voltage-gated channel, shaker-related
subfamily, beta member 1 isoform 1 [Homo sapiens]
Length = 419
Score = 80.9 bits (198), Expect = 1e-15
Identities = 80/295 (27%), Positives = 133/295 (45%), Gaps = 23/295 (7%)
Query: 20 GRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAI 79
G+ D +T A+ E G DTA VY+ G++E ILG + + G + I TK
Sbjct: 114 GQISDEVAERLMTIAY-ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY 172
Query: 80 PLFGNSLKPDS------LRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQ 133
+G + + + L+ SL+RLQ VD+ + + PD +TP+EE +RA +
Sbjct: 173 --WGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVIN 230
Query: 134 EGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQ-VETELFPCLRHFGL 192
+G + G S ++A E+ E ++ + I P Q Y+ R+ VE +L G+
Sbjct: 231 QGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGV 290
Query: 193 RFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVE-KA 251
++PLA G+++GKY NG R + + +E + L +
Sbjct: 291 GAMTWSPLACGIISGKY----GNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSP 346
Query: 252 LQAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGP 306
+ G + P + A W L+ +V+LG S+ EQL +NL A + P
Sbjct: 347 IAERLGCTLPQLAVA---WC-----LRNEGVSSVLLGSSTPEQLIENLGAIQVLP 393
>gi|27436971 potassium voltage-gated channel, shaker-related
subfamily, beta member 3 [Homo sapiens]
Length = 404
Score = 70.5 bits (171), Expect = 2e-12
Identities = 74/291 (25%), Positives = 125/291 (42%), Gaps = 20/291 (6%)
Query: 20 GRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAI 79
G ++ T+ V E G DTA VY+ G++E LG + G I TK
Sbjct: 102 GSQISDETAEDVLTVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIF 161
Query: 80 PLFGNSLKPDS------LRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQ 133
+G + + + L SL+RLQ VD+ + + D + P+EE +RA +
Sbjct: 162 --WGGQAETERGLSRKHIIEGLRGSLERLQLGYVDIVFANRSDPNCPMEEIVRAMTYVIN 219
Query: 134 EGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQ-VETELFPCLRHFGL 192
+G + G S + A E+ E ++ + I P Q ++ R+ VE +L G+
Sbjct: 220 QGLALYWGTSRWGAAEIMEAYSMARQFNLIPPVCEQAEHHLFQREKVEMQLPELYHKIGV 279
Query: 193 RFYAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVEKAL 252
+ PLA GL+T KY +G+ P + +++ E + A V L
Sbjct: 280 GSVTWYPLACGLITSKY-----DGRVPDTCRASIKGYQWLKDKVQSEDGKKQQAKVMDLL 334
Query: 253 QAAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAE 303
A+ ++ + W L+ +V+LG+SS EQL ++L A +
Sbjct: 335 PVAHQLGC-TVAQLAIAWC-----LRSEGVSSVLLGVSSAEQLIEHLGALQ 379
>gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens]
Length = 323
Score = 52.8 bits (125), Expect = 4e-07
Identities = 47/145 (32%), Positives = 68/145 (46%), Gaps = 15/145 (10%)
Query: 24 DAPTSAAV--TRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDT--KAI 79
+ P S A+ T+ +E G ID+A +Y+ + GL +R +D VK +
Sbjct: 28 EVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
Query: 80 PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVE 139
L+ NS +P+ +R LE SLK LQ VDL+ +H P P EE + + GK +
Sbjct: 84 KLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI----PKDENGKILF 139
Query: 140 LGLSNYAAWEVAEICT---LCKSNG 161
+ A WE E C L KS G
Sbjct: 140 DTVDLCATWEAVEKCKDAGLAKSIG 164
>gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens]
Length = 323
Score = 52.4 bits (124), Expect = 6e-07
Identities = 47/145 (32%), Positives = 67/145 (46%), Gaps = 15/145 (10%)
Query: 24 DAPTSAAV--TRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDT--KAI 79
+ P S A+ + +E G ID+A VY+ + GL +R +D VK +
Sbjct: 28 EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
Query: 80 PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVE 139
L+ NS +P+ +R LE SLK LQ VDL+ +H P P EE + + GK +
Sbjct: 84 KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI----PKDENGKILF 139
Query: 140 LGLSNYAAWEVAEICT---LCKSNG 161
+ A WE E C L KS G
Sbjct: 140 DTVDLCATWEAMEKCKDAGLAKSIG 164
>gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens]
Length = 323
Score = 52.4 bits (124), Expect = 6e-07
Identities = 47/145 (32%), Positives = 67/145 (46%), Gaps = 15/145 (10%)
Query: 24 DAPTSAAV--TRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDT--KAI 79
+ P S A+ + +E G ID+A VY+ + GL +R +D VK +
Sbjct: 28 EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
Query: 80 PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVE 139
L+ NS +P+ +R LE SLK LQ VDL+ +H P P EE + + GK +
Sbjct: 84 KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVI----PKDENGKILF 139
Query: 140 LGLSNYAAWEVAEICT---LCKSNG 161
+ A WE E C L KS G
Sbjct: 140 DTVDLCATWEAMEKCKDAGLAKSIG 164
>gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens]
Length = 323
Score = 50.4 bits (119), Expect = 2e-06
Identities = 44/136 (32%), Positives = 64/136 (47%), Gaps = 13/136 (9%)
Query: 31 VTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDT--KAIPLFGNSLKP 88
VT+ +E G ID+A++Y+ + GL +R +D VK + L+ +P
Sbjct: 37 VTKLAIEAGFRHIDSAYLYNNEEQV----GLAIRSKIADGSVKREDIFYTSKLWCTFFQP 92
Query: 89 DSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVELGLSNYAAW 148
++ LE+SLK+LQ VDL+ LH P P E L + GK + + A W
Sbjct: 93 QMVQPALESSLKKLQLDYVDLYLLHFPMALKPGETPL----PKDENGKVIFDTVDLSATW 148
Query: 149 EVAEICT---LCKSNG 161
EV E C L KS G
Sbjct: 149 EVMEKCKDAGLAKSIG 164
>gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens]
Length = 323
Score = 45.8 bits (107), Expect = 5e-05
Identities = 44/145 (30%), Positives = 64/145 (44%), Gaps = 15/145 (10%)
Query: 24 DAPTSAA--VTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDT--KAI 79
+ P S A VT+ +E G ID+A +Y+ + GL +R +D VK +
Sbjct: 28 EVPRSKALEVTKLAIEAGFRHIDSAHLYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
Query: 80 PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEGKFVE 139
L+ +P+ +R LE SLK+ Q VDL+ +H P P EE + GK +
Sbjct: 84 KLWSTFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPGEE----LSPTDENGKVIF 139
Query: 140 LGLSNYAAWEVAEICT---LCKSNG 161
+ WE E C L KS G
Sbjct: 140 DIVDLCTTWEAMEKCKDAGLAKSIG 164
>gi|207028673 hypothetical protein LOC100134257 [Homo sapiens]
Length = 139
Score = 43.9 bits (102), Expect = 2e-04
Identities = 33/96 (34%), Positives = 49/96 (51%), Gaps = 8/96 (8%)
Query: 24 DAPTSAAV--TRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDT--KAI 79
+ P S A+ + +E G ID+A VY+ + GL +R +D VK +
Sbjct: 28 EVPKSKALEAVKLAIEAGFHHIDSAHVYNNEEQV----GLAIRSKIADGSVKREDIFYTS 83
Query: 80 PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMP 115
L+ NS +P+ +R LE SLK LQ VDL+ +H P
Sbjct: 84 KLWSNSHRPELVRPALERSLKNLQLDYVDLYLIHFP 119
>gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens]
Length = 325
Score = 33.5 bits (75), Expect = 0.27
Identities = 48/199 (24%), Positives = 75/199 (37%), Gaps = 44/199 (22%)
Query: 30 AVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIP--------- 80
A + L G+ ID A +Y G I L +G KA+P
Sbjct: 31 AAVKYALSVGYRHIDCAAIY--GNEPEIGEALKEDVGPG--------KAVPREELFVTSK 80
Query: 81 LFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPD-------------------HSTPV 121
L+ P+ + L +L LQ +DL+ +H P ST
Sbjct: 81 LWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHY 140
Query: 122 EETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVET 181
+ET +A L +G LGLSN+ + ++ +I ++ + P V Q + Q
Sbjct: 141 KETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS----VRPAVLQVECHPYLAQ--N 194
Query: 182 ELFPCLRHFGLRFYAFNPL 200
EL + GL A++PL
Sbjct: 195 ELIAHCQARGLEVTAYSPL 213
>gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens]
Length = 325
Score = 33.5 bits (75), Expect = 0.27
Identities = 48/199 (24%), Positives = 75/199 (37%), Gaps = 44/199 (22%)
Query: 30 AVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAIP--------- 80
A + L G+ ID A +Y G I L +G KA+P
Sbjct: 31 AAVKYALSVGYRHIDCAAIY--GNEPEIGEALKEDVGPG--------KAVPREELFVTSK 80
Query: 81 LFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPD-------------------HSTPV 121
L+ P+ + L +L LQ +DL+ +H P ST
Sbjct: 81 LWNTKHHPEDVEPALRKTLADLQLEYLDLYLMHWPYAFERGDNPFPKNADGTICYDSTHY 140
Query: 122 EETLRACHQLHQEGKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQVET 181
+ET +A L +G LGLSN+ + ++ +I ++ + P V Q + Q
Sbjct: 141 KETWKALEALVAKGLVQALGLSNFNSRQIDDILSVAS----VRPAVLQVECHPYLAQ--N 194
Query: 182 ELFPCLRHFGLRFYAFNPL 200
EL + GL A++PL
Sbjct: 195 ELIAHCQARGLEVTAYSPL 213
>gi|71999153 hypothetical protein LOC23334 [Homo sapiens]
Length = 2533
Score = 30.4 bits (67), Expect = 2.3
Identities = 21/51 (41%), Positives = 25/51 (49%), Gaps = 3/51 (5%)
Query: 283 DAVILG-MSSLEQLEQNLAAAEEGPL--EPAVVDAFNQAWHLVTHECPNYF 330
DA +G M S E L Q + E GPL EP V D +Q HE P +F
Sbjct: 101 DAACIGSMLSFEYLIQLCQSKEWGPLPPEPRVSDGLDQGGDTCVHEIPFHF 151
>gi|219555718 synaptonemal complex central element protein 1 isoform
4 [Homo sapiens]
Length = 351
Score = 30.0 bits (66), Expect = 3.0
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 5/94 (5%)
Query: 69 DCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRAC 128
+C+ +I + + K LR E L+ L DL+ HMP+ L +
Sbjct: 132 ECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSS 191
Query: 129 -HQLHQEGKFVELGLSNYAAWEVAEICTLCKSNG 161
QL +E K V+ L + ++C+LC + G
Sbjct: 192 KEQLLKEEKLVKATLEDVK----HQLCSLCGAEG 221
>gi|219555716 synaptonemal complex central element protein 1 isoform
3 [Homo sapiens]
Length = 318
Score = 30.0 bits (66), Expect = 3.0
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 5/94 (5%)
Query: 69 DCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRAC 128
+C+ +I + + K LR E L+ L DL+ HMP+ L +
Sbjct: 132 ECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSS 191
Query: 129 -HQLHQEGKFVELGLSNYAAWEVAEICTLCKSNG 161
QL +E K V+ L + ++C+LC + G
Sbjct: 192 KEQLLKEEKLVKATLEDVK----HQLCSLCGAEG 221
>gi|18640754 synaptonemal complex central element protein 1 isoform
1 [Homo sapiens]
Length = 282
Score = 30.0 bits (66), Expect = 3.0
Identities = 24/94 (25%), Positives = 40/94 (42%), Gaps = 5/94 (5%)
Query: 69 DCRVKIDTKAIPLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRAC 128
+C+ +I + + K LR E L+ L DL+ HMP+ L +
Sbjct: 96 ECKERISALNLQIEEEKNKQRQLRLAFEEQLEDLMGQHKDLWDFHMPERLAKEICALDSS 155
Query: 129 -HQLHQEGKFVELGLSNYAAWEVAEICTLCKSNG 161
QL +E K V+ L + ++C+LC + G
Sbjct: 156 KEQLLKEEKLVKATLEDVK----HQLCSLCGAEG 185
>gi|225690604 alpha-synuclein isoform NACP140 [Homo sapiens]
Length = 140
Score = 29.3 bits (64), Expect = 5.1
Identities = 32/112 (28%), Positives = 45/112 (40%), Gaps = 6/112 (5%)
Query: 217 KQPVGRFFGNTW-AEMYRNRYWKEHHFEGIALV-EKALQAAYGASAPSMTSATLRWMYHH 274
KQ V G T +Y KE G+A V EK + +T T
Sbjct: 23 KQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTA---VAQ 79
Query: 275 SQLQGAHGDAVILGMSSLEQLEQNLAAA-EEGPLEPAVVDAFNQAWHLVTHE 325
++GA A G +QL +N A +EG LE VD N+A+ + + E
Sbjct: 80 KTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEE 131
>gi|225690602 alpha-synuclein isoform NACP140 [Homo sapiens]
Length = 140
Score = 29.3 bits (64), Expect = 5.1
Identities = 32/112 (28%), Positives = 45/112 (40%), Gaps = 6/112 (5%)
Query: 217 KQPVGRFFGNTW-AEMYRNRYWKEHHFEGIALV-EKALQAAYGASAPSMTSATLRWMYHH 274
KQ V G T +Y KE G+A V EK + +T T
Sbjct: 23 KQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTA---VAQ 79
Query: 275 SQLQGAHGDAVILGMSSLEQLEQNLAAA-EEGPLEPAVVDAFNQAWHLVTHE 325
++GA A G +QL +N A +EG LE VD N+A+ + + E
Sbjct: 80 KTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEE 131
>gi|4507109 alpha-synuclein isoform NACP140 [Homo sapiens]
Length = 140
Score = 29.3 bits (64), Expect = 5.1
Identities = 32/112 (28%), Positives = 45/112 (40%), Gaps = 6/112 (5%)
Query: 217 KQPVGRFFGNTW-AEMYRNRYWKEHHFEGIALV-EKALQAAYGASAPSMTSATLRWMYHH 274
KQ V G T +Y KE G+A V EK + +T T
Sbjct: 23 KQGVAEAAGKTKEGVLYVGSKTKEGVVHGVATVAEKTKEQVTNVGGAVVTGVTA---VAQ 79
Query: 275 SQLQGAHGDAVILGMSSLEQLEQNLAAA-EEGPLEPAVVDAFNQAWHLVTHE 325
++GA A G +QL +N A +EG LE VD N+A+ + + E
Sbjct: 80 KTVEGAGSIAAATGFVKKDQLGKNEEGAPQEGILEDMPVDPDNEAYEMPSEE 131
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.135 0.420
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,663,597
Number of Sequences: 37866
Number of extensions: 537900
Number of successful extensions: 1082
Number of sequences better than 10.0: 25
Number of HSP's better than 10.0 without gapping: 16
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1044
Number of HSP's gapped (non-prelim): 28
length of query: 331
length of database: 18,247,518
effective HSP length: 103
effective length of query: 228
effective length of database: 14,347,320
effective search space: 3271188960
effective search space used: 3271188960
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.