Guide to the Human Genome
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Name: CYP2D6 Sequence: fasta or formatted (497aa) NCBI GI: 40805836
Description:

cytochrome P450, family 2, subfamily D, polypeptide 6 isoform 1

Referenced in:

Cytochrome P450 Enzymes

Other entries for this name:
alt prot [446aa] cytochrome P450, family 2, subfamily D, polypeptide 6 isoform 2
Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             8.2         41           2
 C cysteine            1.4          7           1
 D aspartate           4.6         23           2
 E glutamate           6.0         30           2
 F phenylalanine       6.6         33           2
 G glycine             6.6         33           1
 H histidine           3.2         16           2
 I isoleucine          3.0         15           1
 K lysine              2.4         12           2
 L leucine            13.3         66           3
 M methionine          2.0         10           1
 N asparagine          2.4         12           1
 P proline             7.6         38           2
 Q glutamine           4.4         22           2
 R arginine            7.6         38           3
 S serine              4.4         22           2
 T threonine           5.2         26           2
 V valine              8.0         40           3
 W tryptophan          1.4          7           1
 Y tyrosine            1.2          6           1
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   cytochrome P450, family 2, subfamily D, polypeptide ... 
CYP2D6                0.869   cytochrome P450, family 2, subfamily D, polypeptide ...
CYP2J2                0.357   cytochrome P450, family 2, subfamily J, polypeptide ...
CYP2C8                0.337   cytochrome P450, family 2, subfamily C, polypeptide ...
CYP2U1                0.330   cytochrome P450, family 2, subfamily U, polypeptide ...
CYP2C19               0.327   cytochrome P450, family 2, subfamily C, polypeptide 1...
CYP2B6                0.323   cytochrome P450, family 2, subfamily B, polypeptide 6...
CYP2C9                0.323   cytochrome P450, family 2, subfamily C, polypeptide ...
CYP2C18               0.322   cytochrome P450 family 2 subfamily C polypeptide 18 ...
CYP2E1                0.320   cytochrome P450, family 2, subfamily E, polypeptide ...
CYP2R1                0.310   cytochrome P450, family 2, subfamily R, polypeptide ...
CYP2F1                0.309   cytochrome P450, family 2, subfamily F, polypeptide ...
CYP2W1                0.307   cytochrome P450, family 2, subfamily W, polypeptide ...
CYP2A13               0.303   cytochrome P450, family 2, subfamily A, polypeptide ...
CYP2A6                0.289   cytochrome P450, family 2, subfamily A, polypeptide...
CYP2S1                0.284   cytochrome P450, family 2, subfamily S, polypeptide ...
CYP2A7                0.282   cytochrome P450, family 2, subfamily A, polypeptide ...
CYP2A7                0.247   cytochrome P450, family 2, subfamily A, polypeptide ...
CYP1B1                0.222   cytochrome P450, family 1, subfamily B, polypeptide...
CYP1A1                0.221   cytochrome P450, family 1, subfamily A, polypeptide 1...
CYP1A2                0.208   cytochrome P450, family 1, subfamily A, polypeptide ...
CYP2C18               0.179   cytochrome P450 family 2 subfamily C polypeptide 18...
CYP17A1               0.168   cytochrome P450, family 17 
CYP21A2               0.158   cytochrome P450, family 21, subfamily A, polypeptide...
CYP21A2               0.131   cytochrome P450, family 21, subfamily A, polypeptid...
CYP3A4                0.080   cytochrome P450, family 3, subfamily A, polypeptide ...
CYP4V2                0.076   cytochrome P450, family 4, subfamily v, polypeptide...
CYP3A7                0.073   cytochrome P450, family 3, subfamily A, polypeptide 7...
CYP3A5                0.072   cytochrome P450, family 3, subfamily A, polypeptide 5...
CYP27C1               0.069   cytochrome P450, family 27, subfamily C, polypeptid...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
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