Search of human proteins with 40255260

Search of human proteins with 40255260

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|40255260 phosphotyrosine interaction domain containing 1
isoform 1 [Homo sapiens]
         (248 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|40255260 phosphotyrosine interaction domain containing 1 isof...   516   e-147
gi|154816208 phosphotyrosine interaction domain containing 1 iso...   430   e-121
gi|31377557 hypothetical protein LOC131583 [Homo sapiens]              47   2e-05
gi|46409306 family with sequence similarity 43, member B [Homo s...    45   8e-05
gi|132626790 low density lipoprotein receptor adaptor protein 1 ...    35   0.046
gi|156416003 succinate dehydrogenase complex, subunit A, flavopr...    32   0.39 
gi|169165769 PREDICTED: similar to succinate dehydrogenase compl...    32   0.67 
gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo...    32   0.67 
gi|31542779 tripartite motif family-like 1 [Homo sapiens]              32   0.67 
gi|239756098 PREDICTED: hypothetical protein [Homo sapiens]            30   2.0  
gi|239750629 PREDICTED: hypothetical protein XP_002347479 [Homo ...    30   2.5  
gi|239744936 PREDICTED: hypothetical protein XP_002343312 [Homo ...    30   2.5  
gi|156105707 SNF related kinase [Homo sapiens]                         28   5.7  
gi|156105705 SNF related kinase [Homo sapiens]                         28   5.7  
gi|18034775 PHD finger protein 20 [Homo sapiens]                       28   7.4  
gi|239754648 PREDICTED: hypothetical protein [Homo sapiens]            28   9.7  
gi|239749207 PREDICTED: hypothetical protein [Homo sapiens]            28   9.7  
gi|239508971 PREDICTED: hypothetical protein [Homo sapiens]            28   9.7  
gi|24432026 kelch-like [Homo sapiens]                                  28   9.7  

>gi|40255260 phosphotyrosine interaction domain containing 1 isoform
           1 [Homo sapiens]
          Length = 248

 Score =  516 bits (1329), Expect = e-147
 Identities = 248/248 (100%), Positives = 248/248 (100%)

Query: 1   MPRIAGNHLMLEESRTCSSPELLDGVWPCQPLHFGLPASEMHFQTMLKSKLNVLTLKKEP 60
           MPRIAGNHLMLEESRTCSSPELLDGVWPCQPLHFGLPASEMHFQTMLKSKLNVLTLKKEP
Sbjct: 1   MPRIAGNHLMLEESRTCSSPELLDGVWPCQPLHFGLPASEMHFQTMLKSKLNVLTLKKEP 60

Query: 61  LPAVIFHEPEAIELCTTTPLMKTRTHSGCKVTYLGKVSTTGMQFLSGCTEKPVIELWKKH 120
           LPAVIFHEPEAIELCTTTPLMKTRTHSGCKVTYLGKVSTTGMQFLSGCTEKPVIELWKKH
Sbjct: 61  LPAVIFHEPEAIELCTTTPLMKTRTHSGCKVTYLGKVSTTGMQFLSGCTEKPVIELWKKH 120

Query: 121 TLAREDVFPANALLEIRPFQVWLHHLDHKGEATVHMDTFQVARIAYCTADHNVSPNIFAW 180
           TLAREDVFPANALLEIRPFQVWLHHLDHKGEATVHMDTFQVARIAYCTADHNVSPNIFAW
Sbjct: 121 TLAREDVFPANALLEIRPFQVWLHHLDHKGEATVHMDTFQVARIAYCTADHNVSPNIFAW 180

Query: 181 VYREINDDLSYQMDCHAVECESKLEAKKLAHAMMEAFRKTFHSMKSDGRIHSNSSSEEVS 240
           VYREINDDLSYQMDCHAVECESKLEAKKLAHAMMEAFRKTFHSMKSDGRIHSNSSSEEVS
Sbjct: 181 VYREINDDLSYQMDCHAVECESKLEAKKLAHAMMEAFRKTFHSMKSDGRIHSNSSSEEVS 240

Query: 241 QELESDDG 248
           QELESDDG
Sbjct: 241 QELESDDG 248


>gi|154816208 phosphotyrosine interaction domain containing 1
           isoform 2 [Homo sapiens]
          Length = 217

 Score =  430 bits (1106), Expect = e-121
 Identities = 210/214 (98%), Positives = 211/214 (98%), Gaps = 2/214 (0%)

Query: 37  PASE--MHFQTMLKSKLNVLTLKKEPLPAVIFHEPEAIELCTTTPLMKTRTHSGCKVTYL 94
           PA+E   HFQTMLKSKLNVLTLKKEPLPAVIFHEPEAIELCTTTPLMKTRTHSGCKVTYL
Sbjct: 4   PATERLQHFQTMLKSKLNVLTLKKEPLPAVIFHEPEAIELCTTTPLMKTRTHSGCKVTYL 63

Query: 95  GKVSTTGMQFLSGCTEKPVIELWKKHTLAREDVFPANALLEIRPFQVWLHHLDHKGEATV 154
           GKVSTTGMQFLSGCTEKPVIELWKKHTLAREDVFPANALLEIRPFQVWLHHLDHKGEATV
Sbjct: 64  GKVSTTGMQFLSGCTEKPVIELWKKHTLAREDVFPANALLEIRPFQVWLHHLDHKGEATV 123

Query: 155 HMDTFQVARIAYCTADHNVSPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKLAHAMM 214
           HMDTFQVARIAYCTADHNVSPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKLAHAMM
Sbjct: 124 HMDTFQVARIAYCTADHNVSPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKLAHAMM 183

Query: 215 EAFRKTFHSMKSDGRIHSNSSSEEVSQELESDDG 248
           EAFRKTFHSMKSDGRIHSNSSSEEVSQELESDDG
Sbjct: 184 EAFRKTFHSMKSDGRIHSNSSSEEVSQELESDDG 217


>gi|31377557 hypothetical protein LOC131583 [Homo sapiens]
          Length = 423

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 38/154 (24%), Positives = 64/154 (41%), Gaps = 11/154 (7%)

Query: 91  VTYLGKVSTTGMQFLSGCTEKPVIELWKKHTLAREDVFPANALLEIRPFQVWLHHLDHKG 150
           V YLG  +T   +   GCT+  V ++W K    R+        L +    + + H + + 
Sbjct: 72  VLYLGNATTIQARG-DGCTDLAVGKIWSKSEAGRQGT---KMKLTVSAQGIRMVHAEERA 127

Query: 151 -EATVHMDTFQVARIAYCTADHNVSPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKL 209
                H+  + + R+ YC AD  + P +FAWVYR      +  + CHAV      +A+ +
Sbjct: 128 LRRPGHL--YLLHRVTYCVADARL-PKVFAWVYRHELKHKAVMLRCHAVLVSKPEKAQAM 184

Query: 210 AHAMMEAFRKTFHSMKSDGRIHSNSSSEEVSQEL 243
           A  + +         K   R+     +    QEL
Sbjct: 185 ALLLYQTSANALAEFK---RLKRRDDARHQQQEL 215


>gi|46409306 family with sequence similarity 43, member B [Homo
           sapiens]
          Length = 329

 Score = 44.7 bits (104), Expect = 8e-05
 Identities = 27/84 (32%), Positives = 39/84 (46%), Gaps = 4/84 (4%)

Query: 159 FQVARIAYCTADHNVSPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKLAHAMMEAFR 218
           + + RI YCTAD    P +FAWVYR      +  + CHAV      +A+ LA  + +   
Sbjct: 141 YLLPRITYCTADGR-HPRVFAWVYRHQARHKAVVLRCHAVLLARAHKARALARLLRQTAL 199

Query: 219 KTFHSMKSDGRIHSNSSSEEVSQE 242
             F   K   R+   S +  V Q+
Sbjct: 200 AAFSDFK---RLQRQSDARHVRQQ 220


>gi|132626790 low density lipoprotein receptor adaptor protein 1
           [Homo sapiens]
          Length = 308

 Score = 35.4 bits (80), Expect = 0.046
 Identities = 17/66 (25%), Positives = 36/66 (54%), Gaps = 4/66 (6%)

Query: 156 MDTFQVARIAYCTADHNVSPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKLAHAMME 215
           ++   + RI+YCTAD  +   +FA++ +  ++     ++CHA  C  +  A+ +   + +
Sbjct: 108 IENVSIYRISYCTAD-KMHDKVFAYIAQSQHNQ---SLECHAFLCTKRKMAQAVTLTVAQ 163

Query: 216 AFRKTF 221
           AF+  F
Sbjct: 164 AFKVAF 169


>gi|156416003 succinate dehydrogenase complex, subunit A,
           flavoprotein precursor [Homo sapiens]
          Length = 664

 Score = 32.3 bits (72), Expect = 0.39
 Identities = 15/34 (44%), Positives = 19/34 (55%)

Query: 105 LSGCTEKPVIELWKKHTLAREDVFPANALLEIRP 138
           + G  +KP  E W+KHTL+  DV      LE RP
Sbjct: 610 IQGQQKKPFEEHWRKHTLSYVDVGTGKVTLEYRP 643


>gi|169165769 PREDICTED: similar to succinate dehydrogenase complex,
           subunit A, flavoprotein (Fp) [Homo sapiens]
          Length = 109

 Score = 31.6 bits (70), Expect = 0.67
 Identities = 14/34 (41%), Positives = 19/34 (55%)

Query: 105 LSGCTEKPVIELWKKHTLAREDVFPANALLEIRP 138
           + G  +KP  E W+KHTL+  DV      +E RP
Sbjct: 55  IQGQQKKPFEEHWRKHTLSYVDVSTGKVTVEYRP 88


>gi|78217386 RAB GTPase activating protein 1-like isoform A [Homo
           sapiens]
          Length = 815

 Score = 31.6 bits (70), Expect = 0.67
 Identities = 21/102 (20%), Positives = 46/102 (45%), Gaps = 6/102 (5%)

Query: 152 ATVHMDTFQVARIAYCTADHNVSPNIFAWVYREINDDLSYQMDCHAVECESKLEAKKLAH 211
           + V + +F + ++ +C   H+ +     + + E +   S +   H   CE K    ++ +
Sbjct: 187 SNVEIASFPIYKVLFCARGHDGTTESNCFAFTESSHG-SEEFQIHVFSCEIKEAVSRILY 245

Query: 212 AMMEAFRKTFHSMK--SDGRIHSNSS---SEEVSQELESDDG 248
           +   AF+++   +    D  I +  S   +  VS E++ DDG
Sbjct: 246 SFCTAFKRSSRQVSDVKDSVIPTPDSDVFTFSVSLEVKEDDG 287


>gi|31542779 tripartite motif family-like 1 [Homo sapiens]
          Length = 468

 Score = 31.6 bits (70), Expect = 0.67
 Identities = 13/37 (35%), Positives = 24/37 (64%)

Query: 39  SEMHFQTMLKSKLNVLTLKKEPLPAVIFHEPEAIELC 75
           +E H +  L+  LN+L ++++   AV+ HE E ++LC
Sbjct: 131 AEEHHREKLQEILNLLRVRRKEAQAVLTHEKERVKLC 167


>gi|239756098 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 260

 Score = 30.0 bits (66), Expect = 2.0
 Identities = 20/58 (34%), Positives = 26/58 (44%), Gaps = 1/58 (1%)

Query: 105 LSGCTEKPVIELWKKHTLAREDVFPANALLEIRPFQVWLHHLDH-KGEATVHMDTFQV 161
           +SGC   P      + T AR+       +LE+   QV LH  DH  G+    MD  QV
Sbjct: 49  VSGCLGGPSYVPGSERTRARQAAHLLQVVLEVEESQVSLHLADHFHGQCLFFMDDGQV 106


>gi|239750629 PREDICTED: hypothetical protein XP_002347479 [Homo
           sapiens]
          Length = 271

 Score = 29.6 bits (65), Expect = 2.5
 Identities = 20/58 (34%), Positives = 26/58 (44%), Gaps = 1/58 (1%)

Query: 105 LSGCTEKPVIELWKKHTLAREDVFPANALLEIRPFQVWLHHLDH-KGEATVHMDTFQV 161
           +SGC   P      + T AR+       +LE+   QV LH  DH  G+    MD  QV
Sbjct: 60  VSGCLGGPSYVPGSERTRARQAAHLLQVVLEVEEGQVSLHLADHFHGQCLFFMDDGQV 117


>gi|239744936 PREDICTED: hypothetical protein XP_002343312 [Homo
           sapiens]
          Length = 271

 Score = 29.6 bits (65), Expect = 2.5
 Identities = 20/58 (34%), Positives = 26/58 (44%), Gaps = 1/58 (1%)

Query: 105 LSGCTEKPVIELWKKHTLAREDVFPANALLEIRPFQVWLHHLDH-KGEATVHMDTFQV 161
           +SGC   P      + T AR+       +LE+   QV LH  DH  G+    MD  QV
Sbjct: 60  VSGCLGGPSYVPGSERTRARQAAHLLQVVLEVEEGQVSLHLADHFHGQCLFFMDDGQV 117


>gi|156105707 SNF related kinase [Homo sapiens]
          Length = 765

 Score = 28.5 bits (62), Expect = 5.7
 Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 3/65 (4%)

Query: 181 VYREINDDLSYQMDCHAVECESKLEAKKLAHAMMEAFRKTFHSMKSDGRIHSNSSSEEVS 240
           ++ E   D  + MD        KL   K+  A      K +H  KS GR  S SSSE   
Sbjct: 489 IFEEGESDDEFDMD---ENLPPKLSRLKMNIASPGTVHKRYHRRKSQGRGSSCSSSETSD 545

Query: 241 QELES 245
            + ES
Sbjct: 546 DDSES 550


>gi|156105705 SNF related kinase [Homo sapiens]
          Length = 765

 Score = 28.5 bits (62), Expect = 5.7
 Identities = 21/65 (32%), Positives = 27/65 (41%), Gaps = 3/65 (4%)

Query: 181 VYREINDDLSYQMDCHAVECESKLEAKKLAHAMMEAFRKTFHSMKSDGRIHSNSSSEEVS 240
           ++ E   D  + MD        KL   K+  A      K +H  KS GR  S SSSE   
Sbjct: 489 IFEEGESDDEFDMD---ENLPPKLSRLKMNIASPGTVHKRYHRRKSQGRGSSCSSSETSD 545

Query: 241 QELES 245
            + ES
Sbjct: 546 DDSES 550


>gi|18034775 PHD finger protein 20 [Homo sapiens]
          Length = 1012

 Score = 28.1 bits (61), Expect = 7.4
 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 7/62 (11%)

Query: 188 DLSYQMDCHAVECESKLEAKKLAHAMMEAF---RKTFHSMKSDGRIH----SNSSSEEVS 240
           DL ++  C  V+C       KL H  M+ F    K+    +S G+ H      S+S++ S
Sbjct: 447 DLDHKFRCKVVDCLKFFRKAKLLHYHMKYFHGMEKSLEPEESPGKRHVQTRGPSASDKPS 506

Query: 241 QE 242
           QE
Sbjct: 507 QE 508


>gi|239754648 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 377

 Score = 27.7 bits (60), Expect = 9.7
 Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 3/52 (5%)

Query: 69  PEAIELCTTTPLMKTRTHS-GCKVTYLGKVSTTGMQFLSGCTEKPVI--ELW 117
           P+A  +    P+   + HS GC+VTYLG       Q L    E+ V+  E W
Sbjct: 179 PQACRVLGMQPVCVMQDHSLGCQVTYLGNPDPHPGQELGPADERLVVFAEAW 230


>gi|239749207 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 369

 Score = 27.7 bits (60), Expect = 9.7
 Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 3/52 (5%)

Query: 69  PEAIELCTTTPLMKTRTHS-GCKVTYLGKVSTTGMQFLSGCTEKPVI--ELW 117
           P+A  +    P+   + HS GC+VTYLG       Q L    E+ V+  E W
Sbjct: 171 PQACRVLGMQPVCVMQDHSLGCQVTYLGNPDPHPGQELGPADERLVVFAEAW 222


>gi|239508971 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 369

 Score = 27.7 bits (60), Expect = 9.7
 Identities = 18/52 (34%), Positives = 25/52 (48%), Gaps = 3/52 (5%)

Query: 69  PEAIELCTTTPLMKTRTHS-GCKVTYLGKVSTTGMQFLSGCTEKPVI--ELW 117
           P+A  +    P+   + HS GC+VTYLG       Q L    E+ V+  E W
Sbjct: 171 PQACRVLGMQPVCVMQDHSLGCQVTYLGNPDPHPGQELGPADERLVVFAEAW 222


>gi|24432026 kelch-like [Homo sapiens]
          Length = 634

 Score = 27.7 bits (60), Expect = 9.7
 Identities = 21/87 (24%), Positives = 38/87 (43%), Gaps = 3/87 (3%)

Query: 37  PASEMHFQTMLKSKLNVLTLKKEPLPAVIFHEPEAIELCTTTPLMKTRTHSGCKVTYLGK 96
           P  E      L  KL+   L+     A+++H  E+++    +P  + R+   C V + G 
Sbjct: 247 PLMEAEVLQRLHDKLDPSPLRDTVASALMYHRNESLQPSLQSPQTELRSDFQCVVGF-GG 305

Query: 97  VSTTGMQFLSGCTE--KPVIELWKKHT 121
           + +T    LS   +   P++  WK  T
Sbjct: 306 IHSTPSTVLSDQAKYLNPLLGEWKHFT 332


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.132    0.407 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 9,810,759
Number of Sequences: 37866
Number of extensions: 417480
Number of successful extensions: 960
Number of sequences better than 10.0: 19
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 949
Number of HSP's gapped (non-prelim): 20
length of query: 248
length of database: 18,247,518
effective HSP length: 100
effective length of query: 148
effective length of database: 14,460,918
effective search space: 2140215864
effective search space used: 2140215864
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.