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Search of human proteins with 40068065
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|40068065 hypothetical protein LOC54058 [Homo sapiens]
(322 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|40068065 hypothetical protein LOC54058 [Homo sapiens] 671 0.0
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ... 54 2e-07
gi|151301053 RNA binding motif protein 33 [Homo sapiens] 49 8e-06
gi|116284398 WAS/WASL interacting protein family, member 1 [Homo... 45 7e-05
gi|38373695 WAS/WASL interacting protein family, member 1 [Homo ... 45 7e-05
gi|209977097 tripartite motif-containing 66 [Homo sapiens] 45 7e-05
gi|153792074 proline rich 12 [Homo sapiens] 45 7e-05
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 44 2e-04
gi|117938768 GNAS complex locus alex [Homo sapiens] 43 3e-04
gi|118572599 formin homology 2 domain containing 1 [Homo sapiens] 43 4e-04
gi|238859557 regulatory factor X1 [Homo sapiens] 42 6e-04
gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Ho... 42 6e-04
gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Ho... 42 6e-04
gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Ho... 42 6e-04
gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Hom... 42 6e-04
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 42 6e-04
gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens] 42 7e-04
gi|60460889 Myb protein P42POP [Homo sapiens] 42 7e-04
gi|110349719 titin isoform N2-A [Homo sapiens] 42 0.001
gi|47132519 Ras association and pleckstrin homology domains 1 is... 42 0.001
gi|21071077 dishevelled-associated activator of morphogenesis 1 ... 42 0.001
gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens] 41 0.001
gi|21040326 SON DNA-binding protein isoform F [Homo sapiens] 41 0.001
gi|21040314 SON DNA-binding protein isoform B [Homo sapiens] 41 0.001
gi|23510413 sorting nexin 26 [Homo sapiens] 40 0.002
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 40 0.002
gi|40288197 GATA binding protein 6 [Homo sapiens] 40 0.003
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 40 0.003
gi|32307177 forkhead box G1 [Homo sapiens] 40 0.003
gi|157785645 SPEG complex locus [Homo sapiens] 40 0.003
>gi|40068065 hypothetical protein LOC54058 [Homo sapiens]
Length = 322
Score = 671 bits (1731), Expect = 0.0
Identities = 322/322 (100%), Positives = 322/322 (100%)
Query: 1 MARSRLPATSLRKPWKLDRQKLPSPDSGHSLLCGWSPGGKARPAGNTGAWAPAEQFFPAS 60
MARSRLPATSLRKPWKLDRQKLPSPDSGHSLLCGWSPGGKARPAGNTGAWAPAEQFFPAS
Sbjct: 1 MARSRLPATSLRKPWKLDRQKLPSPDSGHSLLCGWSPGGKARPAGNTGAWAPAEQFFPAS 60
Query: 61 NRTREGGGLWPPLPLQSSPAAPTMLDSSAAEQVTRLTLKLLGQKLEQERQNVEGGPEGLH 120
NRTREGGGLWPPLPLQSSPAAPTMLDSSAAEQVTRLTLKLLGQKLEQERQNVEGGPEGLH
Sbjct: 61 NRTREGGGLWPPLPLQSSPAAPTMLDSSAAEQVTRLTLKLLGQKLEQERQNVEGGPEGLH 120
Query: 121 LEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSALPPELPP 180
LEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSALPPELPP
Sbjct: 121 LEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSALPPELPP 180
Query: 181 TGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSIKE 240
TGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSIKE
Sbjct: 181 TGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSIKE 240
Query: 241 DMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVHHHHHHHHA 300
DMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVHHHHHHHHA
Sbjct: 241 DMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVHHHHHHHHA 300
Query: 301 VWPPGAATVLQPAPSLWTPGPP 322
VWPPGAATVLQPAPSLWTPGPP
Sbjct: 301 VWPPGAATVLQPAPSLWTPGPP 322
>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
sapiens]
Length = 1362
Score = 53.5 bits (127), Expect = 2e-07
Identities = 47/141 (33%), Positives = 60/141 (42%), Gaps = 20/141 (14%)
Query: 179 PPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSI 238
PPT +LP+ P P LP P P ++ QQL QQP P PQ P Q+
Sbjct: 940 PPTPLLPSVKVQSQPPPP----LPPPPHP--SVQQQLQQQPPPPPPPQPQPPPQQQH--- 990
Query: 239 KEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRV----PRAARPRLPAVHHH 294
+ + LQ Q + Q PP Q PPH PP P+ A+P+ HHH
Sbjct: 991 -QPPPRPVHLQPMQFSTHIQQ-----PPPPQGQQPPHPPPGQQPPPPQPAKPQQVIQHHH 1044
Query: 295 HHHHHAVWPPGAATVLQPAPS 315
HH P + L+ APS
Sbjct: 1045 SPRHHKS-DPYSTGHLREAPS 1064
Score = 38.9 bits (89), Expect = 0.006
Identities = 39/141 (27%), Positives = 53/141 (37%), Gaps = 31/141 (21%)
Query: 188 SPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSIKEDMVELLL 247
+P+P+ PP P QPP Q QQP PPP + P Q + ++K +
Sbjct: 749 APAPVPQQPP----PPPQQPPPPPPPQQQQQP--PPPPPPPSMPQQAAPAMKSSPPPFIA 802
Query: 248 LQNAQVHQLVLQNWMLKALPPALQDP-------------PHVPPRVPRAARPRLPAVHHH 294
QV L Q LP ++ DP P +PP +P+ P H
Sbjct: 803 ---TQVPVLEPQ------LPGSVFDPIGHFTQPILHLPQPELPPHLPQPPEHSTPP---H 850
Query: 295 HHHHHAVWPPGAATVLQPAPS 315
+ H V PP L PS
Sbjct: 851 LNQHAVVSPPALHNALPQQPS 871
Score = 37.7 bits (86), Expect = 0.014
Identities = 38/143 (26%), Positives = 56/143 (39%), Gaps = 19/143 (13%)
Query: 175 PPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQR 234
PP+ PP P P P PP P++PQ A ++ P + Q+P Q
Sbjct: 760 PPQQPPPPPPPQQQQQPPPPPPP----PSMPQQAAPAMKSSPPPFIATQVP---VLEPQL 812
Query: 235 SGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPH--VPPRVPRAARPRLPAVH 292
GS+ + + Q +L + LPP L PP PP + + A PA+H
Sbjct: 813 PGSVFDPI--------GHFTQPIL-HLPQPELPPHLPQPPEHSTPPHLNQHAVVSPPALH 863
Query: 293 HHHHHHHAVWPPGAATVLQPAPS 315
+ + P A L P P+
Sbjct: 864 NALPQQPS-RPSNRAAALPPKPA 885
Score = 33.9 bits (76), Expect = 0.20
Identities = 15/45 (33%), Positives = 18/45 (40%)
Query: 278 PRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
P+ + P HHHHHH + A QP P P PP
Sbjct: 723 PKSKKKGHPGREQKKHHHHHHQQMQQAPAPVPQQPPPPPQQPPPP 767
Score = 32.3 bits (72), Expect = 0.58
Identities = 33/132 (25%), Positives = 43/132 (32%), Gaps = 32/132 (24%)
Query: 175 PPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQ--PLIAQIPPPQAFPT 232
P + T ++ P PL PP +P PQPP Q Q P+IA P P T
Sbjct: 230 PDLIVQTPVMTVVPPQPLQTPPP---VPPQPQPPPAPAPQPVQSHPPIIAATPQP--VKT 284
Query: 233 QRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVH 292
++ K D P DP H PP +P P+ +
Sbjct: 285 KKGVKRKAD-----------------------TTTPTTIDPIHEPPSLP--PEPKTTKLG 319
Query: 293 HHHHHHHAVWPP 304
V PP
Sbjct: 320 QRRESSRPVKPP 331
Score = 32.3 bits (72), Expect = 0.58
Identities = 44/171 (25%), Positives = 62/171 (36%), Gaps = 34/171 (19%)
Query: 169 ALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQ 228
AL +ALP + P+ + A PP+ P P T LPQ P+ PPQ
Sbjct: 861 ALHNALPQQ-------PSRPSNRAAALPPKPARPPAVSPALTQTPLLPQPPM---AQPPQ 910
Query: 229 AF-----PTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKAL-PPALQDPPH------- 275
P + + + L LQ Q +L + +++ PP L PPH
Sbjct: 911 VLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQPPPPLPPPPHPSVQQQL 970
Query: 276 -VPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQP---APSLWTPGPP 322
P P +P+ P H PP LQP + + P PP
Sbjct: 971 QQQPPPPPPPQPQPPPQQQHQ-------PPPRPVHLQPMQFSTHIQQPPPP 1014
Score = 30.8 bits (68), Expect = 1.7
Identities = 12/31 (38%), Positives = 12/31 (38%)
Query: 292 HHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
HHHHHH P P P P PP
Sbjct: 738 HHHHHHQQMQQAPAPVPQQPPPPPQQPPPPP 768
>gi|151301053 RNA binding motif protein 33 [Homo sapiens]
Length = 1170
Score = 48.5 bits (114), Expect = 8e-06
Identities = 44/145 (30%), Positives = 53/145 (36%), Gaps = 38/145 (26%)
Query: 180 PTGILPTASPS------------PLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPP 227
P GIL + P P P P + LPT QP Q PL +PPP
Sbjct: 537 PVGILHFSQPGSATTRPFIPPRQPFLPGPGQPFLPTHTQPNL-------QGPLHPPLPPP 589
Query: 228 QAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPR 287
Q+ Q+ HQ Q PP Q PP PP+ P +
Sbjct: 590 HQPQPQQPQQQPPP-------QHQPPHQPPHQP------PPQHQPPPQHPPQHPPQHQ-- 634
Query: 288 LPAVHHHHHHHHAVWPPGAATVLQP 312
HHHHHHH +V PP + QP
Sbjct: 635 ----HHHHHHHLSVPPPPLMPMSQP 655
Score = 33.1 bits (74), Expect = 0.34
Identities = 42/157 (26%), Positives = 57/157 (36%), Gaps = 47/157 (29%)
Query: 173 ALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPT 232
AL P PP ++P A P P P PP+ QP ++ Q P QPL+ P P
Sbjct: 307 ALLPTQPP--VVPQAPPPP--PPPPQ------QQPIRSLFQPQPLQPLLPVQHPHHPSPP 356
Query: 233 QRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVH 292
Q G +E P + PP V P+ P+ +H
Sbjct: 357 Q--GMHMPPQLE---------------------TPRMMMTPPPVTPQQPK-------NIH 386
Query: 293 HHHHHHHAVWPPGAATVL----QPAPSLWT---PGPP 322
+ H V P +L QP P++ PGPP
Sbjct: 387 INPHFKGTVVTPVQVPLLPVPSQPRPAVGPQRFPGPP 423
>gi|116284398 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 45.4 bits (106), Expect = 7e-05
Identities = 43/151 (28%), Positives = 53/151 (35%), Gaps = 24/151 (15%)
Query: 165 PSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPP-ATIIQQLPQQPLIAQ 223
PSR AL PP PP G P+ + P PP+ P VP P + Q P P
Sbjct: 256 PSR-ALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPS 314
Query: 224 IPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRA 283
P P P SG N + +L +N L + P L P P P
Sbjct: 315 RPGPPPLPPSSSG-------------NDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP 361
Query: 284 ARPRLPAVHHHHHHHHAVWPPGAATVLQPAP 314
+ P V PPG + L P P
Sbjct: 362 SERPPPPVRD---------PPGRSGPLPPPP 383
Score = 39.7 bits (91), Expect = 0.004
Identities = 44/152 (28%), Positives = 57/152 (37%), Gaps = 24/152 (15%)
Query: 174 LPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQ 233
+PP P G P + P P+ P PR I + + + P+QP PPP FP
Sbjct: 169 MPPPRPDVGSKPDSIPPPV-PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPP--FPGN 225
Query: 234 RSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPP----ALQDPPHVPPRVPRAARPRLP 289
R ++ + L ++ LPP AL D P PP P RP +
Sbjct: 226 RGTALGGGSIRQSPLSSSSPFS------NRPPLPPTPSRALDDKP-PPPPPPVGNRPSI- 277
Query: 290 AVHHHHHHHHAVWPPGAATVLQPAPSLWTPGP 321
H AV PP P PS TP P
Sbjct: 278 -------HREAVPPPPPQNNKPPVPS--TPRP 300
Score = 29.3 bits (64), Expect = 4.9
Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 15/76 (19%)
Query: 165 PSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPP----ATIIQQLPQQPL 220
PS G G PP P+ P P DPP P P PP + + LP P
Sbjct: 349 PSPGRSGPLPPP--------PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATP- 399
Query: 221 IAQIPPPQAFPTQRSG 236
Q+P + RSG
Sbjct: 400 --QLPSRSGVDSPRSG 413
Score = 28.5 bits (62), Expect = 8.4
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 17/80 (21%)
Query: 168 GALGSALP--PELPP-TGI-LPTASPSP-LAPDPPRIILPTVPQPPATIIQQLPQQPL-- 220
G+ ALP P+LP +G+ P + P P L PD P P P P +I P
Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCED 448
Query: 221 ----------IAQIPPPQAF 230
I+ +PPP+ +
Sbjct: 449 EWESRFYFHPISDLPPPEPY 468
>gi|38373695 WAS/WASL interacting protein family, member 1 [Homo
sapiens]
Length = 503
Score = 45.4 bits (106), Expect = 7e-05
Identities = 43/151 (28%), Positives = 53/151 (35%), Gaps = 24/151 (15%)
Query: 165 PSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPP-ATIIQQLPQQPLIAQ 223
PSR AL PP PP G P+ + P PP+ P VP P + Q P P
Sbjct: 256 PSR-ALDDKPPPPPPPVGNRPSIHREAVPPPPPQNNKPPVPSTPRPSASSQAPPPPPPPS 314
Query: 224 IPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRA 283
P P P SG N + +L +N L + P L P P P
Sbjct: 315 RPGPPPLPPSSSG-------------NDETPRLPQRNLSLSSSTPPLPSPGRSGPLPPPP 361
Query: 284 ARPRLPAVHHHHHHHHAVWPPGAATVLQPAP 314
+ P V PPG + L P P
Sbjct: 362 SERPPPPVRD---------PPGRSGPLPPPP 383
Score = 39.7 bits (91), Expect = 0.004
Identities = 44/152 (28%), Positives = 57/152 (37%), Gaps = 24/152 (15%)
Query: 174 LPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQ 233
+PP P G P + P P+ P PR I + + + P+QP PPP FP
Sbjct: 169 MPPPRPDVGSKPDSIPPPV-PSTPRPIQSSPHNRGSPPVPGGPRQPSPGPTPPP--FPGN 225
Query: 234 RSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPP----ALQDPPHVPPRVPRAARPRLP 289
R ++ + L ++ LPP AL D P PP P RP +
Sbjct: 226 RGTALGGGSIRQSPLSSSSPFS------NRPPLPPTPSRALDDKP-PPPPPPVGNRPSI- 277
Query: 290 AVHHHHHHHHAVWPPGAATVLQPAPSLWTPGP 321
H AV PP P PS TP P
Sbjct: 278 -------HREAVPPPPPQNNKPPVPS--TPRP 300
Score = 29.3 bits (64), Expect = 4.9
Identities = 24/76 (31%), Positives = 29/76 (38%), Gaps = 15/76 (19%)
Query: 165 PSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPP----ATIIQQLPQQPL 220
PS G G PP P+ P P DPP P P PP + + LP P
Sbjct: 349 PSPGRSGPLPPP--------PSERPPPPVRDPPGRSGPLPPPPPVSRNGSTSRALPATP- 399
Query: 221 IAQIPPPQAFPTQRSG 236
Q+P + RSG
Sbjct: 400 --QLPSRSGVDSPRSG 413
Score = 28.5 bits (62), Expect = 8.4
Identities = 24/80 (30%), Positives = 34/80 (42%), Gaps = 17/80 (21%)
Query: 168 GALGSALP--PELPP-TGI-LPTASPSP-LAPDPPRIILPTVPQPPATIIQQLPQQPL-- 220
G+ ALP P+LP +G+ P + P P L PD P P P P +I P
Sbjct: 389 GSTSRALPATPQLPSRSGVDSPRSGPRPPLPPDRPSAGAPPPPPPSTSIRNGFQDSPCED 448
Query: 221 ----------IAQIPPPQAF 230
I+ +PPP+ +
Sbjct: 449 EWESRFYFHPISDLPPPEPY 468
>gi|209977097 tripartite motif-containing 66 [Homo sapiens]
Length = 1216
Score = 45.4 bits (106), Expect = 7e-05
Identities = 47/156 (30%), Positives = 63/156 (40%), Gaps = 28/156 (17%)
Query: 175 PPELPP--------TGILPTASPSPLAPDPPRIILPTVP-QPPAT-------IIQQLPQQ 218
PPE+ P + +LP +P PP+++ P + QPP + QQL Q
Sbjct: 350 PPEMVPQQLGSLQCSALLPREKELACSPHPPKLLQPWLETQPPVEQESTSQRLGQQLTSQ 409
Query: 219 PLIAQIPPPQ-------AFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQ 271
P+ I PPQ A PT ++ SI+ L+ + Q Q L PP L
Sbjct: 410 PVC--IVPPQDVQQGAHAQPTLQTPSIQVQFGHHQKLKLSHFQQQPQQQ--LPPPPPPLP 465
Query: 272 DPPHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAA 307
PP P P+ P LP H H PPG A
Sbjct: 466 HPPPPLPPPPQQPHPPLPPSQHLASSQHES-PPGPA 500
>gi|153792074 proline rich 12 [Homo sapiens]
Length = 2036
Score = 45.4 bits (106), Expect = 7e-05
Identities = 53/215 (24%), Positives = 73/215 (33%), Gaps = 25/215 (11%)
Query: 114 GGPEGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSA 173
GGP G E ED LQ+ ++ L + L + GP RG
Sbjct: 681 GGPPGTPYELAKEDPQRYHLQSVIRTSASLDEGATAALELGLGRLKEKKKGPERGG---E 737
Query: 174 LPPELPPTGILPTASPSPLA-------PDPPRIILPTVPQPPATIIQQL-PQQPLIAQIP 225
P L + + A L P PP T P P +++ P PL+ P
Sbjct: 738 TPEGLATSVVHYGAGAKELGAFLQKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPP 797
Query: 226 PPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAAR 285
PPQ P+ +L +A + L PA +D PP P
Sbjct: 798 PPQLLPS--------------VLSHAPSPSPSASKVGVHLLEPATRDGAPQPPPPPPPPP 843
Query: 286 PRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPG 320
P +P H H + P + L+P SL PG
Sbjct: 844 PPMPLQLEAHLRSHGLEPAAPSPRLRPEESLDPPG 878
Score = 42.7 bits (99), Expect = 4e-04
Identities = 36/131 (27%), Positives = 44/131 (33%), Gaps = 44/131 (33%)
Query: 165 PSRGALGSALPP---ELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLI 221
PS + G+ PP E PP P +P P P PP P +P PP ++ P P
Sbjct: 1440 PSANSNGTPEPPLLEEKPPPTPPPAPTPQPQPPPPPPPPQPALPSPP-PLVAPTPSSPPP 1498
Query: 222 AQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPP--R 279
+PPP PPA+ PP PP
Sbjct: 1499 PPLPPPP--------------------------------------PPAMPSPPPPPPPAA 1520
Query: 280 VPRAARPRLPA 290
P AA P PA
Sbjct: 1521 APLAAPPEEPA 1531
Score = 34.7 bits (78), Expect = 0.12
Identities = 22/64 (34%), Positives = 29/64 (45%), Gaps = 4/64 (6%)
Query: 165 PSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQI 224
P + AL S PP + PT P++ P P P PP +P+ P PP L P
Sbjct: 1477 PPQPALPSP-PPLVAPT---PSSPPPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAA 1532
Query: 225 PPPQ 228
P P+
Sbjct: 1533 PSPE 1536
Score = 30.0 bits (66), Expect = 2.9
Identities = 14/34 (41%), Positives = 16/34 (47%), Gaps = 2/34 (5%)
Query: 175 PPELPPTGILPTASPSPLAPDPPRIILPTVPQPP 208
PP PP + P+ L P PP P VP PP
Sbjct: 1305 PPLSPPKSVPPSVPARGLQPQPP--ATPAVPHPP 1336
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 43.9 bits (102), Expect = 2e-04
Identities = 64/238 (26%), Positives = 83/238 (34%), Gaps = 47/238 (19%)
Query: 116 PEGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSAL- 174
PE L P E+ P L AL R L E+ L S P + S L
Sbjct: 462 PEASRLSPPPEELPASPLPEALHLSRPL-----EESPLSPPPEESPLSPPPESSPFSPLE 516
Query: 175 ------PPELPPTGIL-------PTASP-------SPLAPDPPRIILPTVPQPPATIIQQ 214
P E PP+ L P ASP SPL+P P LPT P P A+ +
Sbjct: 517 ESPLSPPEESPPSPALETPLSPPPEASPLSPPFEESPLSPPPEE--LPTSPPPEASRLSP 574
Query: 215 LPQQPLIA-------QIPPPQA---FPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLK 264
P++ ++ PPP+A FP + E L + +L
Sbjct: 575 PPEESPMSPPPEESPMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSP 634
Query: 265 ALPPALQDPPHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
PP + P PP V R + LP V + PP + L P P PP
Sbjct: 635 MSPPPEESPMSPPPEVSRLS--PLPVVSR-------LSPPPEESPLSPPPEESPTSPP 683
Score = 35.8 bits (81), Expect = 0.053
Identities = 42/149 (28%), Positives = 54/149 (36%), Gaps = 56/149 (37%)
Query: 165 PSRGALGSALPPELPPTGIL--------------PTASP---SPLAPDP----------P 197
P + +A PP L P G L P A+P +P++P P P
Sbjct: 938 PLSPIITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISPPPEANCTDPEPVP 997
Query: 198 RIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLV 257
+ILP P P P P++ + PPQ P LLQ H LV
Sbjct: 998 PMILPPSPGSPVG-----PASPILMEPLPPQCSP---------------LLQ----HSLV 1033
Query: 258 LQNWMLKALPPALQDPPHVPPRVPRAARP 286
QN PP+ PP +P VP P
Sbjct: 1034 PQN-----SPPSQCSPPALPLSVPSPLSP 1057
Score = 33.5 bits (75), Expect = 0.26
Identities = 31/124 (25%), Positives = 51/124 (41%), Gaps = 7/124 (5%)
Query: 115 GPEGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSAL 174
GP+ L+ +Q A K ++ Q+ ++QHLL +++ Q AL
Sbjct: 3710 GPDSRLLQERQLQLQQQRMQLAQKLQQQQQQQQQQQHLLGQVAIQQQQQQGPGVQTNQAL 3769
Query: 175 PPELPPTGILPTAS-----PSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQA 229
P+ P G++P +S L+P PP+ + ++QQ L Q P Q
Sbjct: 3770 GPK--PQGLMPPSSHQGLLVQQLSPQPPQGPQGMLGPAQVAVLQQQHPGALGPQGPHRQV 3827
Query: 230 FPTQ 233
TQ
Sbjct: 3828 LMTQ 3831
Score = 33.1 bits (74), Expect = 0.34
Identities = 50/195 (25%), Positives = 71/195 (36%), Gaps = 37/195 (18%)
Query: 46 NTGAWAPAEQFFPASNRTREGGGLWPPL-----PLQSSPAAPTMLDSSAAEQVTRLTLKL 100
NTG P S + G G+ P + LQ A L + +Q +L L
Sbjct: 4167 NTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALL 4226
Query: 101 LGQKLEQERQNVEGGPEGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQ 160
+ ++L+Q + + P + EPG + P Q LL +
Sbjct: 4227 MQRQLQQSQAVRQTPP---YQEPGTQTSP-------------------LQGLLGCQPQLG 4264
Query: 161 AWSGPSRGALGSAL-------PPELP-PTGILPTASP-SPLAPDPPRIILPTVPQPPATI 211
+ GP G L PP LP P G L T P+ P PP P P+ P+ +
Sbjct: 4265 GFPGPQTGPLQELGAGPRPQGPPRLPAPPGALSTGPVLGPVHPTPPPSS-PQEPKRPSQL 4323
Query: 212 IQQLPQQPLIAQIPP 226
Q P AQ+PP
Sbjct: 4324 PSPSSQLPTEAQLPP 4338
Score = 33.1 bits (74), Expect = 0.34
Identities = 27/70 (38%), Positives = 33/70 (47%), Gaps = 15/70 (21%)
Query: 172 SALPPELPPTGILPTASPSPLAPDP------PRIILPTVP--QPPATIIQQLPQQPLIAQ 223
SA PPE P + PSPLAP P P + LPT P +PP L P A+
Sbjct: 4907 SAPPPEEP------SPPPSPLAPSPASPPTEPLVELPTEPLAEPPVPSPLPLASSPESAR 4960
Query: 224 IPPPQAFPTQ 233
P P+A P +
Sbjct: 4961 -PKPRARPPE 4969
Score = 29.3 bits (64), Expect = 4.9
Identities = 22/63 (34%), Positives = 28/63 (44%), Gaps = 9/63 (14%)
Query: 175 PPELPPTGILPTASPSPLAPD-----PPRIILPTVPQPPAT-IIQQLPQQPLIAQIPPPQ 228
PPE P P SP+ P+ PP LP P P A + + L + PL PPP+
Sbjct: 443 PPEESPLSPPPEESPTSPPPEASRLSPPPEELPASPLPEALHLSRPLEESPL---SPPPE 499
Query: 229 AFP 231
P
Sbjct: 500 ESP 502
>gi|117938768 GNAS complex locus alex [Homo sapiens]
Length = 626
Score = 43.1 bits (100), Expect = 3e-04
Identities = 79/331 (23%), Positives = 112/331 (33%), Gaps = 59/331 (17%)
Query: 43 PAGNTGAWAPAEQFFPASNRTREGGGLWPPLPLQSSPAAPTMLDSSAAEQVTRLTLKLLG 102
P G+ A P+ Q + + W L P L S E + +
Sbjct: 62 PVGSMQALRPSAQHSWSPEPSVVPDQAWEDTALHQKKLCPLSLTSLPREAAVNFSYR--S 119
Query: 103 QKLEQERQNVEGGPEGLHLEPGNED----RPDDALQTALKRRRDLLQRLREQHL------ 152
Q L QE Q ++G PE L P P++A TAL RR L E+ L
Sbjct: 120 QTLLQEAQVLQGSPELLPRSPKPSGLQRLAPEEA--TALPLRRLCHLSLMEKDLGTTAHP 177
Query: 153 --LDELSRAQAWSGPSRGALGSALPPELPPTGILPTASPSPLAPDPPRI--ILPT----- 203
ELS + SR + LPP LP+ S +P A P R+ +L T
Sbjct: 178 RGFPELSHKSTAAASSRQSRPRVRSASLPPRTRLPSGSQAPSAAHPKRLSDLLLTSRAAA 237
Query: 204 ----VPQPPATI-IQQLPQQPLIAQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVL 258
P P + + L L + PQ+ T R E + ++ Q+ +
Sbjct: 238 PGWRSPDPRSRLAAPPLGSTTLPSTWTAPQSRLTARPSRSPEPQIRESEQRDPQLRR-KQ 296
Query: 259 QNWMLKALPPALQD---------PPHVPPRVPRAARP-------------RLPAVHHHH- 295
Q W +P + PP P R+P +P ++P H
Sbjct: 297 QRWKEPLMPRREEKYPLRGTDPLPPGQPQRIPLPGQPLQPQPILTPGQPQKIPTPGQHQP 356
Query: 296 ----HHHHAVWPPGAATVLQPAPSLWTPGPP 322
H + PG QP P TPG P
Sbjct: 357 ILTPGHSQPIPTPGQPLPPQPIP---TPGRP 384
>gi|118572599 formin homology 2 domain containing 1 [Homo sapiens]
Length = 1164
Score = 42.7 bits (99), Expect = 4e-04
Identities = 57/248 (22%), Positives = 82/248 (33%), Gaps = 55/248 (22%)
Query: 37 PGGKARPAGNTGAWAPAEQFFPASNRTREGGGLWPPLPLQSSPAAPTMLDSSAAEQV--T 94
P G A P G T + PA PAS+ GL + L + + D+S+ +
Sbjct: 382 PTGPASPVGPTSSTGPALLTGPASSPVGPPSGLQASVNLFPTISVAPSADTSSERSIYKA 441
Query: 95 RLTLKLLGQKLEQERQNVEGGPEGLHLEPGNE--DRPD-----DALQTA----------- 136
R + + E++ +G E L NE PD D+ +TA
Sbjct: 442 RFLENVAAAETEKQVALAQGRAETLAGAMPNEAGGHPDARQLWDSPETAPAARTPQSPAP 501
Query: 137 ---LKRRRDLLQRLREQHLLDELSRAQAWSGPSRGA------------------------ 169
L+ +R L +E + W P+R
Sbjct: 502 CVLLRAQRSLAPEPKEPLIPASPKAEPIWELPTRAPRLSIGDLDFSDLGEDEDQDMLNVE 561
Query: 170 ---LGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPP 226
G +P PP +L P P P PP I P P PP + LP +P
Sbjct: 562 SVEAGKDIPAPSPPLPLLSGVPPPPPLPPPPPIKGPFPPPPPLPLAAPLPH-----SVPD 616
Query: 227 PQAFPTQR 234
A PT+R
Sbjct: 617 SSALPTKR 624
>gi|238859557 regulatory factor X1 [Homo sapiens]
Length = 979
Score = 42.4 bits (98), Expect = 6e-04
Identities = 30/76 (39%), Positives = 33/76 (43%), Gaps = 6/76 (7%)
Query: 170 LGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQA 229
L +A PP PP P A P P P PP P PQPP PQ Q P PQA
Sbjct: 9 LQAAPPPSQPPQAP-PQAQPQPPPPPPPAA--PQPPQPPTAAATPQPQYVTELQSPQPQA 65
Query: 230 FPTQRSGSIKEDMVEL 245
P G K+ + EL
Sbjct: 66 QP---PGGQKQYVTEL 78
>gi|68161504 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 42.4 bits (98), Expect = 6e-04
Identities = 54/169 (31%), Positives = 65/169 (38%), Gaps = 32/169 (18%)
Query: 172 SALPPELPPTGILPTA-SPSPL------APDPPRIILPTVPQPPATIIQQ--LPQQPLIA 222
S PP PP LP+A S S L P PP +P P PPAT +Q +P P
Sbjct: 321 SPTPPPPPPP--LPSALSTSSLRASMTSTPPPP---VPPPPPPPATALQAPAVPPPPAPL 375
Query: 223 QI--------PPPQAFP-TQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDP 273
QI PPP A P Q S + + + VH L ++ LPP P
Sbjct: 376 QIAPGVLHPAPPPIAPPLVQPSPPVARAAP---VCETVPVHPL--PQGEVQGLPP----P 426
Query: 274 PHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
P PP P RP P H + P +T P L P PP
Sbjct: 427 PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPP 475
Score = 32.3 bits (72), Expect = 0.58
Identities = 40/148 (27%), Positives = 48/148 (32%), Gaps = 38/148 (25%)
Query: 175 PPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQR 234
PP PP A P P ++ PQ PAT + P PPP P+
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPAT--GRTPVFVSPTPPPPPPPLPSAL 335
Query: 235 SGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVHHH 294
S S L+A + PP PP P A + PAV
Sbjct: 336 STS------------------------SLRASMTSTPPPPVPPPPPPPATALQAPAV--- 368
Query: 295 HHHHHAVWPPGAATVLQPAPSLWTPGPP 322
PP A LQ AP + P PP
Sbjct: 369 --------PPPPAP-LQIAPGVLHPAPP 387
>gi|68161502 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 42.4 bits (98), Expect = 6e-04
Identities = 54/169 (31%), Positives = 65/169 (38%), Gaps = 32/169 (18%)
Query: 172 SALPPELPPTGILPTA-SPSPL------APDPPRIILPTVPQPPATIIQQ--LPQQPLIA 222
S PP PP LP+A S S L P PP +P P PPAT +Q +P P
Sbjct: 321 SPTPPPPPPP--LPSALSTSSLRASMTSTPPPP---VPPPPPPPATALQAPAVPPPPAPL 375
Query: 223 QI--------PPPQAFP-TQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDP 273
QI PPP A P Q S + + + VH L ++ LPP P
Sbjct: 376 QIAPGVLHPAPPPIAPPLVQPSPPVARAAP---VCETVPVHPL--PQGEVQGLPP----P 426
Query: 274 PHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
P PP P RP P H + P +T P L P PP
Sbjct: 427 PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPP 475
Score = 32.3 bits (72), Expect = 0.58
Identities = 40/148 (27%), Positives = 48/148 (32%), Gaps = 38/148 (25%)
Query: 175 PPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQR 234
PP PP A P P ++ PQ PAT + P PPP P+
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPAT--GRTPVFVSPTPPPPPPPLPSAL 335
Query: 235 SGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVHHH 294
S S L+A + PP PP P A + PAV
Sbjct: 336 STS------------------------SLRASMTSTPPPPVPPPPPPPATALQAPAV--- 368
Query: 295 HHHHHAVWPPGAATVLQPAPSLWTPGPP 322
PP A LQ AP + P PP
Sbjct: 369 --------PPPPAP-LQIAPGVLHPAPP 387
>gi|68161500 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 42.4 bits (98), Expect = 6e-04
Identities = 54/169 (31%), Positives = 65/169 (38%), Gaps = 32/169 (18%)
Query: 172 SALPPELPPTGILPTA-SPSPL------APDPPRIILPTVPQPPATIIQQ--LPQQPLIA 222
S PP PP LP+A S S L P PP +P P PPAT +Q +P P
Sbjct: 321 SPTPPPPPPP--LPSALSTSSLRASMTSTPPPP---VPPPPPPPATALQAPAVPPPPAPL 375
Query: 223 QI--------PPPQAFP-TQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDP 273
QI PPP A P Q S + + + VH L ++ LPP P
Sbjct: 376 QIAPGVLHPAPPPIAPPLVQPSPPVARAAP---VCETVPVHPL--PQGEVQGLPP----P 426
Query: 274 PHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
P PP P RP P H + P +T P L P PP
Sbjct: 427 PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPP 475
Score = 32.3 bits (72), Expect = 0.58
Identities = 40/148 (27%), Positives = 48/148 (32%), Gaps = 38/148 (25%)
Query: 175 PPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQR 234
PP PP A P P ++ PQ PAT + P PPP P+
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPAT--GRTPVFVSPTPPPPPPPLPSAL 335
Query: 235 SGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVHHH 294
S S L+A + PP PP P A + PAV
Sbjct: 336 STS------------------------SLRASMTSTPPPPVPPPPPPPATALQAPAV--- 368
Query: 295 HHHHHAVWPPGAATVLQPAPSLWTPGPP 322
PP A LQ AP + P PP
Sbjct: 369 --------PPPPAP-LQIAPGVLHPAPP 387
>gi|4507913 Wiskott-Aldrich syndrome protein family member 1 [Homo
sapiens]
Length = 559
Score = 42.4 bits (98), Expect = 6e-04
Identities = 54/169 (31%), Positives = 65/169 (38%), Gaps = 32/169 (18%)
Query: 172 SALPPELPPTGILPTA-SPSPL------APDPPRIILPTVPQPPATIIQQ--LPQQPLIA 222
S PP PP LP+A S S L P PP +P P PPAT +Q +P P
Sbjct: 321 SPTPPPPPPP--LPSALSTSSLRASMTSTPPPP---VPPPPPPPATALQAPAVPPPPAPL 375
Query: 223 QI--------PPPQAFP-TQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDP 273
QI PPP A P Q S + + + VH L ++ LPP P
Sbjct: 376 QIAPGVLHPAPPPIAPPLVQPSPPVARAAP---VCETVPVHPL--PQGEVQGLPP----P 426
Query: 274 PHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
P PP P RP P H + P +T P L P PP
Sbjct: 427 PPPPPLPPPGIRPSSPVTVTALAHPPSGLHPTPSTAPGPHVPLMPPSPP 475
Score = 32.3 bits (72), Expect = 0.58
Identities = 40/148 (27%), Positives = 48/148 (32%), Gaps = 38/148 (25%)
Query: 175 PPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQR 234
PP PP A P P ++ PQ PAT + P PPP P+
Sbjct: 278 PPPPPPMHGAGDAKPIPTCISSATGLIENRPQSPAT--GRTPVFVSPTPPPPPPPLPSAL 335
Query: 235 SGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPAVHHH 294
S S L+A + PP PP P A + PAV
Sbjct: 336 STS------------------------SLRASMTSTPPPPVPPPPPPPATALQAPAV--- 368
Query: 295 HHHHHAVWPPGAATVLQPAPSLWTPGPP 322
PP A LQ AP + P PP
Sbjct: 369 --------PPPPAP-LQIAPGVLHPAPP 387
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 42.4 bits (98), Expect = 6e-04
Identities = 46/150 (30%), Positives = 64/150 (42%), Gaps = 19/150 (12%)
Query: 174 LPPELPPTGILPTASPSPLAPDP---PRIILPTV--PQPPATIIQQLPQQPLIAQIPP-- 226
LPP LP LPTA+ P+ P P +ILP++ P PPA+ LP Q + PP
Sbjct: 813 LPPALPD---LPTATVPPVPPPQYFSPAVILPSLAAPLPPAS--PALPLQAVKLPHPPGA 867
Query: 227 PQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARP 286
P A P + + LL + V L + + + + L P P P+ A
Sbjct: 868 PLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQ-----LPGQPVYPAAFPQMAPT 922
Query: 287 RLPAVHHHHHHHHAVWPPGAATVLQPAPSL 316
+P HH + PP A L P P+L
Sbjct: 923 DVPPSPHHTVQNMRATPPQPA--LPPQPTL 950
Score = 37.7 bits (86), Expect = 0.014
Identities = 36/121 (29%), Positives = 50/121 (41%), Gaps = 10/121 (8%)
Query: 176 PELPPTGILPTASPSPLAPD----PPRIILPTVP-QPPATIIQQLPQQPLIAQIPPPQAF 230
P LPP PT P P+ P PP+ +LP P +PP ++ P P +PP A
Sbjct: 942 PALPPQ---PTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPAL 998
Query: 231 PTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLPA 290
P R ++ + E Q++L + A+ A Q P VP P LP
Sbjct: 999 PV-RPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQ-VPTVPVPPAAVLSPPLPE 1056
Query: 291 V 291
V
Sbjct: 1057 V 1057
Score = 37.4 bits (85), Expect = 0.018
Identities = 50/171 (29%), Positives = 60/171 (35%), Gaps = 46/171 (26%)
Query: 163 SGPSRGALGSALPP-ELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLI 221
S P G PP + PP PT P LAP P ++P P PP
Sbjct: 714 STPMPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQP---VVPLQPVPPHL----------- 759
Query: 222 AQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVP 281
PP P + G+ + L+ Q+ Q LQ L +PP + P VPP P
Sbjct: 760 ----PPYLAPASQVGAPAQ-------LKPLQMPQAPLQ--PLAQVPPQMPPIPVVPPITP 806
Query: 282 RA-------ARPRLPAVHHHHHHHHAVWPPGAATVLQPA---PSLWTPGPP 322
A A P LP V P PA PSL P PP
Sbjct: 807 LAGIDGLPPALPDLPTA--------TVPPVPPPQYFSPAVILPSLAAPLPP 849
Score = 35.4 bits (80), Expect = 0.069
Identities = 68/287 (23%), Positives = 98/287 (34%), Gaps = 45/287 (15%)
Query: 18 DRQKLPSPDSGHSLLCGWSPGGKAR------PAGNTGAWAPAEQFF----PASNRTREGG 67
DR P H CG G ++R P +++F A + E
Sbjct: 1268 DRGSDPGTSPPHLSTCGLGTGEESRQSQANAPVYQQNVLHTGKRWFIICPVAEHPAPEAP 1327
Query: 68 GLWPPLPLQSSPAAPTMLDSSAAEQVTRLTLKLLGQKLEQERQNVEGGPEGLHLEPGNED 127
PPLPL S P + +A +L+ K L ++ + GP P
Sbjct: 1328 ESSPPLPLSSLPPEASQ---DSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPPGAPPAPL 1384
Query: 128 RPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSALPPELPP--TGILP 185
P TAL + P+ G A P P T L
Sbjct: 1385 APSSPPVTALPQD-------------GAAPATSTMPEPASGTASQAGGPGTPQGLTSELE 1431
Query: 186 TASP------SPLAPDPPRI-ILPTVPQPPATIIQQL--PQQPLIAQIPPPQAFPTQRSG 236
T+ P +PLA P + + P P P A + P++PL PPP P+ SG
Sbjct: 1432 TSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAPREPL----PPPAPEPSPHSG 1487
Query: 237 SIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRA 283
+ + + + L A V + L L + P P VPP+ P A
Sbjct: 1488 TPQPALGQPAPLLPAAVGAVSLATSQLPSPPLG----PTVPPQPPSA 1530
Score = 30.8 bits (68), Expect = 1.7
Identities = 20/58 (34%), Positives = 27/58 (46%), Gaps = 7/58 (12%)
Query: 174 LPPE--LPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQA 229
LPP+ LPP +LP P+ P+P + LP P AT P ++ P P A
Sbjct: 980 LPPQPMLPPQPVLPPQPALPVRPEPLQPHLPEQAAPAAT-----PGSQILLGHPAPYA 1032
Score = 30.4 bits (67), Expect = 2.2
Identities = 33/120 (27%), Positives = 46/120 (38%), Gaps = 21/120 (17%)
Query: 177 ELPPTGILPTA----SPSPLAPDPPRIIL---PTVPQPPATIIQQLPQQPLIAQIPPPQA 229
+LP + P A +P+ + P P + T PQP LP QP++ PP
Sbjct: 905 QLPGQPVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQPVL---PPQPT 961
Query: 230 FPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLP 289
P Q +L Q + Q VL + P L P +P R P +P LP
Sbjct: 962 LPPQ----------PVLPPQPTRPPQPVLPPQPMLPPQPVLPPQPALPVR-PEPLQPHLP 1010
>gi|14269566 megakaryoblastic leukemia 1 protein [Homo sapiens]
Length = 931
Score = 42.0 bits (97), Expect = 7e-04
Identities = 46/189 (24%), Positives = 80/189 (42%), Gaps = 16/189 (8%)
Query: 109 RQNVEGGPEGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRG 168
R +EG + L+ +D+ +AL L++++ L++RL+ Q L++ RAQ P+
Sbjct: 515 RAELEGRDKDQMLQ--EKDKQIEALTRMLRQKQQLVERLKLQ--LEQEKRAQQ-PAPAPA 569
Query: 169 ALGSALPPELPPTGILPTASP-SPLAPDPPRIILPTV---------PQPPATIIQQLPQQ 218
LG+ + E + + P P P P + P P PP+ +++Q Q
Sbjct: 570 PLGTPVKQENSFSSCQLSQQPLGPAHPFNPSLAAPATNHIDPCAVAPGPPSVVVKQEALQ 629
Query: 219 PLIAQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQD-PPHVP 277
P +P PQ + S+ + + L+ ++ LVL A P L P P
Sbjct: 630 PEPEPVPAPQLLLGPQGPSLIKGVAPPTLITDSTGTHLVLTVTNKNADSPGLSSGSPQQP 689
Query: 278 PRVPRAARP 286
P + P
Sbjct: 690 SSQPGSPAP 698
>gi|60460889 Myb protein P42POP [Homo sapiens]
Length = 399
Score = 42.0 bits (97), Expect = 7e-04
Identities = 32/114 (28%), Positives = 50/114 (43%), Gaps = 13/114 (11%)
Query: 176 PELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRS 235
P LPP L +PSP +P PP P+PP T+ P + + +
Sbjct: 225 PPLPPPPPLAQVAPSPPSPPPP-------PRPPPTLSASDPSLDFLRAQQETANAIRELA 277
Query: 236 GSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPRLP 289
G++++ + +L +A + +L + +LPP L PP PP RP LP
Sbjct: 278 GTLRQGLAKLSEALSALLP--LLPGTPVDSLPPPLPPPPPPPP----PPRPVLP 325
Score = 29.6 bits (65), Expect = 3.8
Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 1/46 (2%)
Query: 172 SALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQ 217
SAL P LP T + P P P PP P +P PPA ++ P+
Sbjct: 292 SALLPLLPGTPVDSLPPPLPPPPPPPPPPRPVLP-PPAPKVEITPE 336
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 41.6 bits (96), Expect = 0.001
Identities = 57/264 (21%), Positives = 110/264 (41%), Gaps = 37/264 (14%)
Query: 95 RLTLKLLGQKLEQERQNVEGGPEGLHLEPGNEDRPDDALQTALKR-----RRDLLQRLRE 149
RL L+++ ++E+ + E + E G ++ ++ R R + + R+ E
Sbjct: 10364 RLELEVVEAEVEEIPEEEEFHEVEEYFEEGEFHEVEEFIKLEQHRVEEEHRVEKVHRVIE 10423
Query: 150 QHLLDELSRAQAWSGPSRGALGSA--LPPELPPTGILPTASPSPLAPDPPRII------- 200
+E+ + P +G S +PP+ PPT ++P P P+ P+ I
Sbjct: 10424 VFEAEEVEVFEKPKAPPKGPEISEKIIPPKKPPTKVVPRKEPPAKVPEVPKKIVVEEKVR 10483
Query: 201 LPTVPQ-PPATIIQQLPQQPLIAQ----IPP---PQAFPTQRSGSIKEDMVELLL----- 247
+P P+ PP + + LP + ++ + +PP P+A P + + KE + E +
Sbjct: 10484 VPEEPRVPPTKVPEVLPPKEVVPEKKVPVPPAKKPEAPPPKVPEAPKEVVPEKKVPVPPP 10543
Query: 248 ----LQNAQVHQL----VLQNWMLKALPPALQDPPHVPPRVPRAARP--RLPAVHHHHHH 297
+ +V ++ V + + +A+PP + PP P P+ P ++PA
Sbjct: 10544 KKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPKEVVPEKKVPAAPPKKPE 10603
Query: 298 HHAVWPPGAATVLQPAPSLWTPGP 321
V P A + P + P P
Sbjct: 10604 VTPVKVPEAPKEVVPEKKVPVPPP 10627
Score = 33.1 bits (74), Expect = 0.34
Identities = 29/130 (22%), Positives = 53/130 (40%), Gaps = 15/130 (11%)
Query: 165 PSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLI--A 222
P + A PE+P + P P+ P +P VP+ P ++++ P P+ A
Sbjct: 10739 PKKPEAPPAKVPEVPKEVVPEKKVAVPKKPEVPPAKVPEVPKKP--VLEEKPAVPVPERA 10796
Query: 223 QIPPPQAF-------PTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALP----PALQ 271
+ PPP+ + P + +E V + + +V + K +P P ++
Sbjct: 10797 ESPPPEVYEEPEEIAPEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIK 10856
Query: 272 DPPHVPPRVP 281
P PP+ P
Sbjct: 10857 KPEAPPPKEP 10866
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 41.6 bits (96), Expect = 0.001
Identities = 44/192 (22%), Positives = 75/192 (39%), Gaps = 22/192 (11%)
Query: 151 HLLDELSRAQAWSGPSRGALGSALPPELPPTGILPTASP----------SPLAPDPPRII 200
H + +++ + P + + LPP+ PP ++ +P + AP P
Sbjct: 750 HQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPP 809
Query: 201 LPTVPQPPATIIQQLPQQPLIAQIP-PPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQ 259
+P + PA +P P +P PP P Q+S K L + + V + +
Sbjct: 810 VPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPS--VVKQIAS 867
Query: 260 NWMLKALPPALQD------PPHVPPRVPRA--ARPR-LPAVHHHHHHHHAVWPPGAATVL 310
+ PPA++ P +V P+ P A A+P+ P+ PP ++ V
Sbjct: 868 QFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESSLVF 927
Query: 311 QPAPSLWTPGPP 322
P P P PP
Sbjct: 928 PPPPPSPVPAPP 939
Score = 38.1 bits (87), Expect = 0.011
Identities = 48/182 (26%), Positives = 62/182 (34%), Gaps = 45/182 (24%)
Query: 179 PPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQ---RS 235
P T ++P SP P P P+ P PP P P PPP P+Q +
Sbjct: 601 PYTSLVPPLSPQPKIVTPYTASQPSPPLPPP---PPPPPPPPPPPPPPPPPLPSQSAPSA 657
Query: 236 GSIKEDMVE---LLLLQNAQVHQ---------LVLQNWMLK----------ALPPALQDP 273
GS V+ + LQNA H V+Q+ +K PP P
Sbjct: 658 GSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPP 717
Query: 274 PHVP-------------PRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPG 320
P P P +P+ + P P H H V PP P P + P
Sbjct: 718 PPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPP----TPPPPPPIPAPL 773
Query: 321 PP 322
PP
Sbjct: 774 PP 775
Score = 35.0 bits (79), Expect = 0.090
Identities = 26/110 (23%), Positives = 39/110 (35%), Gaps = 32/110 (29%)
Query: 178 LPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGS 237
+PP G++P P P P P + P P A P P + PPP
Sbjct: 703 VPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCA------PSLPQFSAPPPP---------- 746
Query: 238 IKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPRVPRAARPR 287
++HQ+ + + PP PP +P +P A P+
Sbjct: 747 -------------LKIHQV---QHITQVAPPTPPPPPPIPAPLPPQAPPK 780
Score = 30.4 bits (67), Expect = 2.2
Identities = 42/158 (26%), Positives = 56/158 (35%), Gaps = 15/158 (9%)
Query: 171 GSALPPELPPTGILPTASPSPLAPDPPRIILP--TVPQPPATI--IQQLPQ-QPLIAQIP 225
G PP PP P ++ + L P P LP + P PP I +Q + Q P P
Sbjct: 707 GVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPP 766
Query: 226 PPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQ---NWMLKALPPALQDP----PHVPP 278
PP P K + V +V Q +PPA + P ++PP
Sbjct: 767 PPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPP 826
Query: 279 RVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSL 316
P P P A PP + L P PS+
Sbjct: 827 SPPTPPVPVPPPTLPKQQSFCAKPPP---SPLSPVPSV 861
Score = 29.6 bits (65), Expect = 3.8
Identities = 24/63 (38%), Positives = 29/63 (46%), Gaps = 10/63 (15%)
Query: 176 PELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPT-QR 234
P+ P+ I P SP P PP L P PP+ + P P PPP A PT +
Sbjct: 902 PKWQPSSI-PVPSPD-FPPPPPESSLVFPPPPPSPV--PAPPPP-----PPPTASPTPDK 952
Query: 235 SGS 237
SGS
Sbjct: 953 SGS 955
>gi|21071077 dishevelled-associated activator of morphogenesis 1
[Homo sapiens]
Length = 1078
Score = 41.6 bits (96), Expect = 0.001
Identities = 39/149 (26%), Positives = 59/149 (39%), Gaps = 28/149 (18%)
Query: 103 QKLEQERQNVEGGPEGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHL---------- 152
+K+ +E ++ E E + + + + L + ++ L++ +H
Sbjct: 453 EKMRKEHNELQQKLEKKERECDAKTQEKEEMMQTLNKMKEKLEKETTEHKQVKQQVADLT 512
Query: 153 --LDELSR----AQAWSGPSRGALGSALPPELPPTGILPTASPSPLA----PDPPRIILP 202
L ELSR A GPS GA G P +P + +LP P PL P PP + P
Sbjct: 513 AQLHELSRRAVCASIPGGPSPGAPGGPFPSSVPGS-LLPPPPPPPLPGGMLPPPPPPLPP 571
Query: 203 TVPQPPATIIQQLPQQPLIAQIPPPQAFP 231
P PP P P + I PP P
Sbjct: 572 GGPPPP-------PGPPPLGAIMPPPGAP 593
>gi|162138911 IQ motif and Sec7 domain 2 isoform1 [Homo sapiens]
Length = 1488
Score = 41.2 bits (95), Expect = 0.001
Identities = 56/198 (28%), Positives = 70/198 (35%), Gaps = 30/198 (15%)
Query: 152 LLDELSRAQAWSGPSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATI 211
L D S+ QA G A PP LPP P+ P P P PP L ++P PPA+
Sbjct: 1257 LPDGQSKLQALHAQYCQGPGPAPPPYLPPQQ--PSLPPPPQQP-PPLPQLGSIPPPPASA 1313
Query: 212 IQQLPQQPLIAQ--IPPPQAFPTQRSG-SIKEDMVELLLLQNAQVHQLVLQNWMLKALPP 268
P + A +P PQ + R G + + H L L P
Sbjct: 1314 PPVGPHRHFHAHGPVPGPQHYTLGRPGRAPRRGAGGHPQFAPHGRHPLHQPTSPLPLYSP 1373
Query: 269 ALQDPP------------HVPPRVPRAAR-----PRLPAVHHHHHHH-------HAVWPP 304
A Q PP H P +P A R P + H HH H+ PP
Sbjct: 1374 APQHPPAHKQGPKHFIFSHHPQMMPAAGAAGGPGSRPPGGSYSHPHHPQSPLSPHSPIPP 1433
Query: 305 GAATVLQPAPSLWTPGPP 322
+ P PS TP P
Sbjct: 1434 HPSYPPLPPPSPHTPHSP 1451
Score = 33.5 bits (75), Expect = 0.26
Identities = 27/103 (26%), Positives = 36/103 (34%), Gaps = 18/103 (17%)
Query: 213 QQLPQQPLIAQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQD 272
Q++P P PPP+ + +QR S + L + P
Sbjct: 1178 QRMPPPP---PPPPPEEYKSQRPVSNSSSFLGSLFGSK-------------RGKGPFQMP 1221
Query: 273 PPHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPS 315
PP P A+ + HHHHHHHH G VL S
Sbjct: 1222 PP--PTGQASASSSSASSTHHHHHHHHHGHSHGGLGVLPDGQS 1262
Score = 31.6 bits (70), Expect = 0.99
Identities = 29/93 (31%), Positives = 37/93 (39%), Gaps = 12/93 (12%)
Query: 165 PSRGALGSALPPELPPTGIL-----PTASPSPLAPDPPRIILPTVPQP-PATIIQQLPQQ 218
P+ GA G P PP G P + SP +P PP P +P P P T LP
Sbjct: 1398 PAAGAAGG--PGSRPPGGSYSHPHHPQSPLSPHSPIPPHPSYPPLPPPSPHTPHSPLPPT 1455
Query: 219 ----PLIAQIPPPQAFPTQRSGSIKEDMVELLL 247
PL A PP A P + K + ++
Sbjct: 1456 SPHGPLHASGPPGTANPPSANPKAKPSRISTVV 1488
>gi|21040326 SON DNA-binding protein isoform F [Homo sapiens]
Length = 2426
Score = 41.2 bits (95), Expect = 0.001
Identities = 37/117 (31%), Positives = 54/117 (46%), Gaps = 12/117 (10%)
Query: 117 EGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHL-LDELSRAQAWSGPSRGALGSALP 175
E L L D P + +++ R ++L + + L L E S A A P A
Sbjct: 335 EALRLPEQPVDVPSEIADSSMTRPQELPELPKTTALELQESSVASAMELPGPPATSM--- 391
Query: 176 PEL---PPTGIL----PTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIP 225
PEL P T +L P+A+P P P P +P +P PPAT + +LP P + +P
Sbjct: 392 PELQGPPVTPVLELPGPSATPVPELPGPLSTPVPELPGPPATAVPELP-GPSVTPVP 447
Score = 35.8 bits (81), Expect = 0.053
Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 12/67 (17%)
Query: 172 SALP-PELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQ------PLIAQI 224
SA P PELP P ++P P P PP +P +P P T + QL Q+ P + +
Sbjct: 409 SATPVPELPG----PLSTPVPELPGPPATAVPELPGPSVTPVPQLSQELPGLPAPSMG-L 463
Query: 225 PPPQAFP 231
PPQ P
Sbjct: 464 EPPQEVP 470
Score = 30.8 bits (68), Expect = 1.7
Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 7/82 (8%)
Query: 165 PSRGALGSALPPELPPTG-ILPTASPSPLAPDPPRIILPT-VPQPPATIIQQLPQQPLI- 221
P + LPPE PP G LPT + A + PT VP P+ P+ P+
Sbjct: 1162 PEEPPMTPPLPPEEPPEGPALPTEQSALTAEN----TWPTEVPSSPSEESVSQPEPPVSQ 1217
Query: 222 AQIPPPQAFPTQRSGSIKEDMV 243
++I P A PT S S + V
Sbjct: 1218 SEISEPSAVPTDYSVSASDPSV 1239
>gi|21040314 SON DNA-binding protein isoform B [Homo sapiens]
Length = 2303
Score = 41.2 bits (95), Expect = 0.001
Identities = 37/117 (31%), Positives = 54/117 (46%), Gaps = 12/117 (10%)
Query: 117 EGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQHL-LDELSRAQAWSGPSRGALGSALP 175
E L L D P + +++ R ++L + + L L E S A A P A
Sbjct: 335 EALRLPEQPVDVPSEIADSSMTRPQELPELPKTTALELQESSVASAMELPGPPATSM--- 391
Query: 176 PEL---PPTGIL----PTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIP 225
PEL P T +L P+A+P P P P +P +P PPAT + +LP P + +P
Sbjct: 392 PELQGPPVTPVLELPGPSATPVPELPGPLSTPVPELPGPPATAVPELP-GPSVTPVP 447
Score = 35.8 bits (81), Expect = 0.053
Identities = 25/67 (37%), Positives = 33/67 (49%), Gaps = 12/67 (17%)
Query: 172 SALP-PELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQ------PLIAQI 224
SA P PELP P ++P P P PP +P +P P T + QL Q+ P + +
Sbjct: 409 SATPVPELPG----PLSTPVPELPGPPATAVPELPGPSVTPVPQLSQELPGLPAPSMG-L 463
Query: 225 PPPQAFP 231
PPQ P
Sbjct: 464 EPPQEVP 470
Score = 30.8 bits (68), Expect = 1.7
Identities = 27/82 (32%), Positives = 36/82 (43%), Gaps = 7/82 (8%)
Query: 165 PSRGALGSALPPELPPTG-ILPTASPSPLAPDPPRIILPT-VPQPPATIIQQLPQQPLI- 221
P + LPPE PP G LPT + A + PT VP P+ P+ P+
Sbjct: 1162 PEEPPMTPPLPPEEPPEGPALPTEQSALTAEN----TWPTEVPSSPSEESVSQPEPPVSQ 1217
Query: 222 AQIPPPQAFPTQRSGSIKEDMV 243
++I P A PT S S + V
Sbjct: 1218 SEISEPSAVPTDYSVSASDPSV 1239
>gi|23510413 sorting nexin 26 [Homo sapiens]
Length = 1126
Score = 40.4 bits (93), Expect = 0.002
Identities = 47/179 (26%), Positives = 69/179 (38%), Gaps = 19/179 (10%)
Query: 66 GGGLWPPLPLQSSPAAPTMLDSSAAEQVTRLTLKLLGQKLEQERQNVEGGPEGLH----L 121
GG PP P S P T+ + + E ++ Q E G P L
Sbjct: 613 GGTRAPPQPSGSRPDTVTLRSAKSEESLS-------SQASGAELLGAGGAPASATPTPAL 665
Query: 122 EPGNEDRPDDALQTALKRRRDLLQRLREQHLLDELSRAQAWSGPSRGALGSALPPELPPT 181
PG RP + L+ L +Q + +L AQ GP + S LPP PP
Sbjct: 666 SPGRSLRPH-LIPLLLRGAEAPLTDACQQEMCSKLRGAQGPLGPD---MESPLPP--PPL 719
Query: 182 GIL-PTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSIK 239
+L P +P P +P R++ + + + +Q QQ PP P RS S++
Sbjct: 720 SLLRPGGAPPPPPKNPARLMALALAERAQQVAEQQSQQE-CGGTPPASQSPFHRSLSLE 777
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 40.4 bits (93), Expect = 0.002
Identities = 61/254 (24%), Positives = 87/254 (34%), Gaps = 29/254 (11%)
Query: 25 PDSGHSLLCGWSPGGKARPAGNTGAWAPAEQFFPASNRTREGG-GLWPPLPLQSSPAAPT 83
P+ +S + G SPGG RP +P P+S + + G PP L PA+P
Sbjct: 552 PNPANSWVPGLSPGGSRRPPR-----SPERTLSPSSGYSSQSGTPTLPPKGLAGPPASPG 606
Query: 84 MLDSSAAEQVTRLTLKLLGQKLEQERQNVEGGPEGLHLEPGNEDRPDDALQTALKRRRDL 143
E+VT +L+ G + ++ +P DR + T L R +
Sbjct: 607 KAQPPKPERVT--SLRSPGASVSSSLTSLCSSSS----DPAPSDRSGPQILTPLGDRFVI 660
Query: 144 LQRLREQHLLDELSRAQAWSGPSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPT 203
+ P+ AL A P +P G + T SP +P P+ L
Sbjct: 661 PPHPKVPAPFSPPPSKPRSPNPAAPAL--AAPAVVP--GPVSTTDASPQSPPTPQTTLTP 716
Query: 204 VPQPPATIIQQLPQQPLIAQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWML 263
+ + P Q P PPP P E +VE L NW
Sbjct: 717 LQESPVISKDQSPPPS-----PPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNW-- 769
Query: 264 KALPPALQDPPHVP 277
PP PP P
Sbjct: 770 ---PP---PPPPAP 777
Score = 32.7 bits (73), Expect = 0.44
Identities = 32/119 (26%), Positives = 45/119 (37%), Gaps = 18/119 (15%)
Query: 175 PPELPPTGILPTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQIPPPQ------ 228
PP P ++ S S A +P + P PPA Q L +A PPP+
Sbjct: 742 PPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQDLS----MADFPPPEEAFFSV 797
Query: 229 AFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPALQDPPHVPPR-VPRAARP 286
A P S ++V ++ L +Q PP DPP PP P ++ P
Sbjct: 798 ASPEPAGPSGSPELVSSPAASSSSATALQIQ-------PPGSPDPPPAPPAPAPASSAP 849
Score = 32.0 bits (71), Expect = 0.76
Identities = 35/129 (27%), Positives = 49/129 (37%), Gaps = 22/129 (17%)
Query: 165 PSRGALGSALPPELPPTGIL-PTASPSPLAPDPPRIILPTVPQPPATIIQQLPQQPLIAQ 223
PS G + P LPP G+ P ASP P P + ++ P A++ L +
Sbjct: 580 PSSGYSSQSGTPTLPPKGLAGPPASPGKAQPPKPERVT-SLRSPGASVSSSLTSLCSSSS 638
Query: 224 IPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALP--PALQDPPHVPPRVP 281
P P + RSG Q+ + +++ P PA PP PR P
Sbjct: 639 DPAP----SDRSGP--------------QILTPLGDRFVIPPHPKVPAPFSPPPSKPRSP 680
Query: 282 RAARPRLPA 290
A P L A
Sbjct: 681 NPAAPALAA 689
>gi|40288197 GATA binding protein 6 [Homo sapiens]
Length = 595
Score = 40.0 bits (92), Expect = 0.003
Identities = 18/39 (46%), Positives = 19/39 (48%)
Query: 283 AARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGP 321
AARP HHHHHHHH P + V P W GP
Sbjct: 315 AARPLNGTYHHHHHHHHHHPSPYSPYVGAPLTPAWPAGP 353
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 40.0 bits (92), Expect = 0.003
Identities = 50/227 (22%), Positives = 92/227 (40%), Gaps = 19/227 (8%)
Query: 91 EQVTRLTLKLLGQKLEQERQNVEGGPEGLHLEPGNEDRPDDALQTALKRRRDLLQRLREQ 150
+Q+ R+ L Q+ +Q++Q + + L +P + P Q + L Q+L++
Sbjct: 236 QQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQA--LPQQLQQM 293
Query: 151 HLLDELSRAQAWSGPSRGALGSALPPELPPTG-ILPTASPSPLAPDPPRIILPTVPQPPA 209
H Q P + + P +LPP P S + P +L T QPP
Sbjct: 294 H---HTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQ---MLYT--QPPL 345
Query: 210 TIIQQLPQQPLIAQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKALPPA 269
++ P++ Q PP Q Q+ +++ ++ QV Q L ML + P
Sbjct: 346 KFVRA----PMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLP--MLSSPSPG 399
Query: 270 --LQDPPHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAP 314
+Q P +PP + +P P+ + + P ++ + P+P
Sbjct: 400 QQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSP 446
Score = 37.4 bits (85), Expect = 0.018
Identities = 33/108 (30%), Positives = 40/108 (37%), Gaps = 1/108 (0%)
Query: 213 QQLPQQPLIAQIPPPQAFPTQRSGSIKE-DMVELLLLQNAQVHQLVLQNWMLKALPPALQ 271
QQ QQ LI Q Q+ ++ ++L Q Q Q Q L+A PP Q
Sbjct: 213 QQQQQQHLIKLHHQNQQQIQQQQQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQ 272
Query: 272 DPPHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTP 319
P P P A P+ HH HH P V Q PS P
Sbjct: 273 PPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPP 320
>gi|32307177 forkhead box G1 [Homo sapiens]
Length = 489
Score = 40.0 bits (92), Expect = 0.003
Identities = 16/31 (51%), Positives = 16/31 (51%)
Query: 292 HHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
HHHHHHHH PP A P P P PP
Sbjct: 47 HHHHHHHHHHHPPPPAPQPPPPPQQQQPPPP 77
Score = 29.6 bits (65), Expect = 3.8
Identities = 19/52 (36%), Positives = 21/52 (40%), Gaps = 3/52 (5%)
Query: 179 PPTGILPTASPSPLAPDPPRIILPTVPQP---PATIIQQLPQQPLIAQIPPP 227
PP P P P PP P PQ PA + PQQ L+ PPP
Sbjct: 59 PPPAPQPPPPPQQQQPPPPPPPAPQPPQTRGAPAADDDKGPQQLLLPPPPPP 110
>gi|157785645 SPEG complex locus [Homo sapiens]
Length = 3267
Score = 40.0 bits (92), Expect = 0.003
Identities = 76/297 (25%), Positives = 101/297 (34%), Gaps = 52/297 (17%)
Query: 36 SPGGKARPAGNTGAWAPAEQFFPASNRTREGG-------GLWPPL--PLQSSPAAPTMLD 86
SPG G G A++ R GG GL PL L P M
Sbjct: 2047 SPGATRLARGGLGEGEYAQRLQALRQRLLRGGPEDGKVSGLRGPLLESLGGRARDPRMAR 2106
Query: 87 SSAAEQVTRLTLKLLGQKLEQERQNVEGGPEGLHLEPGNEDRPDDALQTALKRRRDLLQR 146
++++E L + L++ +G E G R L+ + R +R
Sbjct: 2107 AASSEAAPHHQPPLENRGLQKSSSFSQGEAE----PRGRHRRAGAPLEIPVARLG--ARR 2160
Query: 147 LREQHLLDELSRAQAWSGPSRGALGSALPPELPPTGILPTASPSPLAPDPPRIILPTVPQ 206
L+E L LS AQ S A + P P+ P+ +P P AP P + P+
Sbjct: 2161 LQESPSLSALSEAQPSSPARPSAPKPSTPKSAEPSATTPSDAPQPPAPQPAQ---DKAPE 2217
Query: 207 P-PATIIQQLPQQPLIAQIPPPQAFPTQRSGSIKEDMVELLLLQNAQVHQLVLQNWMLKA 265
P P + P PPPQA T + L L AQ+ Q +
Sbjct: 2218 PRPEPVRASKP-------APPPQALQT----------LALPLTPYAQIIQSL-------Q 2253
Query: 266 LPPALQDPPHVPPRVPRAARPRLPAVHHHHHHHHAVWPPGAATVLQPAPSLWTPGPP 322
L Q P P AA P P H A PPGA P+ GPP
Sbjct: 2254 LSGHAQGPSQGP-----AAPPSEPKPHAAVFARVASPPPGAPEKRVPSAG----GPP 2301
Score = 31.6 bits (70), Expect = 0.99
Identities = 22/66 (33%), Positives = 32/66 (48%), Gaps = 10/66 (15%)
Query: 173 ALPPELPPTGILPTASPSPLAPDPPRIIL--PTVPQPPATIIQQLPQQPLIAQIPPPQAF 230
A PP+ PT + P +P+ AP PP + + + P PP+ + L A PPPQ
Sbjct: 2794 ARPPD-SPTSLAPPLAPA--APTPPSVTVSPSSPPTPPSQALSSLK-----AVGPPPQTP 2845
Query: 231 PTQRSG 236
P + G
Sbjct: 2846 PRRHRG 2851
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.134 0.427
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,169,659
Number of Sequences: 37866
Number of extensions: 1163182
Number of successful extensions: 12502
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 235
Number of HSP's successfully gapped in prelim test: 636
Number of HSP's that attempted gapping in prelim test: 7759
Number of HSP's gapped (non-prelim): 3696
length of query: 322
length of database: 18,247,518
effective HSP length: 102
effective length of query: 220
effective length of database: 14,385,186
effective search space: 3164740920
effective search space used: 3164740920
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.5 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.