Guide to the Human Genome
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Name: SRD5A2 Sequence: fasta or formatted (254aa) NCBI GI: 39812447
Description:

3-oxo-5 alpha-steroid 4-dehydrogenase 2

Referenced in:

Steroid Hormones

Composition:

amino acid map
 Amino acid        Percentage    Count  Longest homopolymer
 A alanine             9.8         25           2
 C cysteine            2.0          5           1
 D aspartate           1.6          4           1
 E glutamate           2.8          7           1
 F phenylalanine       8.3         21           2
 G glycine             9.4         24           2
 H histidine           2.8          7           3
 I isoleucine          6.3         16           2
 K lysine              2.8          7           1
 L leucine            14.6         37           2
 M methionine          1.2          3           1
 N asparagine          1.6          4           1
 P proline             6.7         17           2
 Q glutamine           3.5          9           2
 R arginine            5.5         14           1
 S serine              5.5         14           1
 T threonine           3.9         10           1
 V valine              3.9         10           1
 W tryptophan          1.6          4           1
 Y tyrosine            6.3         16           2
Comparative genomics:

Search single species RefSeq proteins at NCBI
   H. sapiens
   M. musculus
   D. rerio
   C. intestinalis
   S. purpuratus
   D. melanogaster
   C. elegans
   A. thaliana
   S. cerevisiae
   E. coli W3110
   A. pernix K1

Search summary

comparative genomics plot

   Figure data

Additional searches of
RefSeq proteins at NCBI

   All
   Eukaryotes
   Bacteria
   Archaea
   Viruses
   Primates
   Mammals
   Vertebrates

Related human proteins:
Protein          Relative score         Description

Self-match            1.000   3-oxo-5 alpha-steroid 4-dehydrogenase 2 
SRD5A1                0.426   steroid-5-alpha-reductase 1 
GPSN2                 0.076   glycoprotein, synaptic 2 
LOC100294376          0.074   PREDICTED: similar to hCG16318 
SRD5A3                0.072   steroid 5 alpha-reductase 3 
SRD5A2L2              0.042   steroid 5 alpha-reductase 2-like 2 
HCN4                  0.018   hyperpolarization activated cyclic nucleotide-gated p...
LOC100288750          0.008   PREDICTED: hypothetical protein 
LOC100288750          0.008   PREDICTED: hypothetical protein XP_002343022 
RAX                   0.008   retina and anterior neural fold homeobox 
TNFSF14               0.006   tumor necrosis factor ligand superfamily, member 14 ...
TRPM8                 0.006   transient receptor potential cation channel, subfam...
Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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