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Search of human proteins with 38424073
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|38424073 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
(1377 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221219024 pleckstrin homology-like domain, family B, member 1... 2714 0.0
gi|38424073 pleckstrin homology-like domain, family B, member 1 ... 2714 0.0
gi|221219026 pleckstrin homology-like domain, family B, member 1... 2553 0.0
gi|197313728 pleckstrin homology-like domain, family B, member 2... 652 0.0
gi|21955172 pleckstrin homology-like domain, family B, member 2 ... 652 0.0
gi|197313732 pleckstrin homology-like domain, family B, member 2... 633 0.0
gi|197313730 pleckstrin homology-like domain, family B, member 2... 633 0.0
gi|157266264 pleckstrin homology-like domain, family B, member 3... 205 2e-52
gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens] 100 2e-20
gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens] 76 3e-13
gi|148746195 trichohyalin [Homo sapiens] 76 3e-13
gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens] 75 3e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 73 2e-12
gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens] 73 2e-12
gi|41322923 plectin 1 isoform 11 [Homo sapiens] 73 2e-12
gi|41322914 plectin 1 isoform 10 [Homo sapiens] 73 2e-12
gi|41322919 plectin 1 isoform 8 [Homo sapiens] 73 2e-12
gi|41322910 plectin 1 isoform 7 [Homo sapiens] 73 2e-12
gi|41322916 plectin 1 isoform 6 [Homo sapiens] 73 2e-12
gi|41322908 plectin 1 isoform 3 [Homo sapiens] 73 2e-12
gi|41322912 plectin 1 isoform 2 [Homo sapiens] 73 2e-12
gi|47607492 plectin 1 isoform 1 [Homo sapiens] 73 2e-12
gi|163965366 nascent polypeptide-associated complex alpha subuni... 72 5e-12
gi|145312241 differentially expressed in FDCP 6 homolog [Homo sa... 71 8e-12
gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 71 8e-12
gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens] 69 2e-11
gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens] 69 2e-11
gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens] 69 2e-11
gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens] 69 2e-11
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 68 5e-11
>gi|221219024 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
Length = 1377
Score = 2714 bits (7036), Expect = 0.0
Identities = 1377/1377 (100%), Positives = 1377/1377 (100%)
Query: 1 MDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITLLPLE 60
MDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITLLPLE
Sbjct: 1 MDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITLLPLE 60
Query: 61 EGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQPTRLTQGC 120
EGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQPTRLTQGC
Sbjct: 61 EGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQPTRLTQGC 120
Query: 121 MLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTPQTATRGP 180
MLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTPQTATRGP
Sbjct: 121 MLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTPQTATRGP 180
Query: 181 SACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPG 240
SACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPG
Sbjct: 181 SACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPG 240
Query: 241 AMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQ 300
AMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQ
Sbjct: 241 AMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQ 300
Query: 301 SRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVA 360
SRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVA
Sbjct: 301 SRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVA 360
Query: 361 ISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSP 420
ISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSP
Sbjct: 361 ISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSP 420
Query: 421 SRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPTRTTPDP 480
SRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPTRTTPDP
Sbjct: 421 SRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPTRTTPDP 480
Query: 481 KLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGSFSGRLSP 540
KLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGSFSGRLSP
Sbjct: 481 KLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGSFSGRLSP 540
Query: 541 AYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQER 600
AYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQER
Sbjct: 541 AYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQER 600
Query: 601 LREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGA 660
LREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGA
Sbjct: 601 LREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGA 660
Query: 661 SGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEER 720
SGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEER
Sbjct: 661 SGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEER 720
Query: 721 AQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKL 780
AQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKL
Sbjct: 721 AQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKL 780
Query: 781 VALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRS 840
VALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRS
Sbjct: 781 VALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRS 840
Query: 841 IAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGG 900
IAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGG
Sbjct: 841 IAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGG 900
Query: 901 RPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQV 960
RPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQV
Sbjct: 901 RPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQV 960
Query: 961 YRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPR 1020
YRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPR
Sbjct: 961 YRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPR 1020
Query: 1021 NLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGP 1080
NLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGP
Sbjct: 1021 NLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGP 1080
Query: 1081 SGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSA 1140
SGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSA
Sbjct: 1081 SGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSA 1140
Query: 1141 SGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESAR 1200
SGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESAR
Sbjct: 1141 SGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESAR 1200
Query: 1201 RQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCR 1260
RQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCR
Sbjct: 1201 RQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCR 1260
Query: 1261 GYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK 1320
GYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK
Sbjct: 1261 GYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK 1320
Query: 1321 KRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN 1377
KRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN
Sbjct: 1321 KRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN 1377
>gi|38424073 pleckstrin homology-like domain, family B, member 1
isoform a [Homo sapiens]
Length = 1377
Score = 2714 bits (7036), Expect = 0.0
Identities = 1377/1377 (100%), Positives = 1377/1377 (100%)
Query: 1 MDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITLLPLE 60
MDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITLLPLE
Sbjct: 1 MDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITLLPLE 60
Query: 61 EGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQPTRLTQGC 120
EGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQPTRLTQGC
Sbjct: 61 EGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQPTRLTQGC 120
Query: 121 MLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTPQTATRGP 180
MLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTPQTATRGP
Sbjct: 121 MLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTPQTATRGP 180
Query: 181 SACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPG 240
SACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPG
Sbjct: 181 SACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPG 240
Query: 241 AMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQ 300
AMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQ
Sbjct: 241 AMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQ 300
Query: 301 SRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVA 360
SRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVA
Sbjct: 301 SRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVA 360
Query: 361 ISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSP 420
ISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSP
Sbjct: 361 ISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSP 420
Query: 421 SRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPTRTTPDP 480
SRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPTRTTPDP
Sbjct: 421 SRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPTRTTPDP 480
Query: 481 KLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGSFSGRLSP 540
KLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGSFSGRLSP
Sbjct: 481 KLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGSFSGRLSP 540
Query: 541 AYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQER 600
AYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQER
Sbjct: 541 AYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQER 600
Query: 601 LREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGA 660
LREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGA
Sbjct: 601 LREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGA 660
Query: 661 SGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEER 720
SGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEER
Sbjct: 661 SGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEER 720
Query: 721 AQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKL 780
AQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKL
Sbjct: 721 AQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKL 780
Query: 781 VALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRS 840
VALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRS
Sbjct: 781 VALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRS 840
Query: 841 IAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGG 900
IAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGG
Sbjct: 841 IAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGG 900
Query: 901 RPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQV 960
RPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQV
Sbjct: 901 RPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQV 960
Query: 961 YRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPR 1020
YRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPR
Sbjct: 961 YRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPR 1020
Query: 1021 NLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGP 1080
NLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGP
Sbjct: 1021 NLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGP 1080
Query: 1081 SGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSA 1140
SGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSA
Sbjct: 1081 SGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSA 1140
Query: 1141 SGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESAR 1200
SGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESAR
Sbjct: 1141 SGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESAR 1200
Query: 1201 RQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCR 1260
RQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCR
Sbjct: 1201 RQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCR 1260
Query: 1261 GYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK 1320
GYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK
Sbjct: 1261 GYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK 1320
Query: 1321 KRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN 1377
KRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN
Sbjct: 1321 KRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN 1377
>gi|221219026 pleckstrin homology-like domain, family B, member 1
isoform b [Homo sapiens]
Length = 1319
Score = 2553 bits (6618), Expect = 0.0
Identities = 1314/1377 (95%), Positives = 1316/1377 (95%), Gaps = 58/1377 (4%)
Query: 1 MDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITLLPLE 60
MDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITLLPLE
Sbjct: 1 MDALNRNQIGPGCQTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITLLPLE 60
Query: 61 EGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQPTRLTQGC 120
EGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQPTRLTQGC
Sbjct: 61 EGRTVIGSAARDISLQGPGLAPEHCYIENLRGTLTLYPCGNACTIDGLPVRQPTRLTQGC 120
Query: 121 MLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTPQTATRGP 180
MLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTPQTATRGP
Sbjct: 121 MLCLGQSTFLRFNHPAEAKWMKSMIPAGGRAPGPPYSPVPAESESLVNGNHTPQTATRGP 180
Query: 181 SACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPG 240
SACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPG
Sbjct: 181 SACASHSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPG 240
Query: 241 AMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQ 300
AMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQ
Sbjct: 241 AMSVGSSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQ 300
Query: 301 SRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVA 360
SRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVA
Sbjct: 301 SRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVA 360
Query: 361 ISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSP 420
ISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSP
Sbjct: 361 ISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSP 420
Query: 421 SRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPTRTTPDP 480
SRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPTRTTPDP
Sbjct: 421 SRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPTRTTPDP 480
Query: 481 KLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGSFSGRLSP 540
KLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGSFSGRLSP
Sbjct: 481 KLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGSFSGRLSP 540
Query: 541 AYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQER 600
AYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQER
Sbjct: 541 AYSLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQER 600
Query: 601 LREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGA 660
LREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGA
Sbjct: 601 LREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGA 660
Query: 661 SGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEER 720
SGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEER
Sbjct: 661 SGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEER 720
Query: 721 AQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKL 780
AQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKL
Sbjct: 721 AQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKL 780
Query: 781 VALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRS 840
VALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRS
Sbjct: 781 VALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRS 840
Query: 841 IAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGG 900
IAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGG
Sbjct: 841 IAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGG 900
Query: 901 RPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQV 960
RPFPKTTSTLKE+ Y+ M G
Sbjct: 901 RPFPKTTSTLKEV-------------YRSKMDG--------------------------- 920
Query: 961 YRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPR 1020
EATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPR
Sbjct: 921 -------EATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPR 973
Query: 1021 NLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGP 1080
NLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGP
Sbjct: 974 NLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGP 1033
Query: 1081 SGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSA 1140
SGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSA
Sbjct: 1034 SGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSA 1093
Query: 1141 SGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESAR 1200
SGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESAR
Sbjct: 1094 SGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESAR 1153
Query: 1201 RQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCR 1260
RQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCR
Sbjct: 1154 RQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCR 1213
Query: 1261 GYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK 1320
GYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK
Sbjct: 1214 GYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAK 1273
Query: 1321 KRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN 1377
SPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN
Sbjct: 1274 -----------SPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFMN 1319
>gi|197313728 pleckstrin homology-like domain, family B, member 2
isoform b [Homo sapiens]
Length = 1237
Score = 652 bits (1683), Expect = 0.0
Identities = 392/850 (46%), Positives = 524/850 (61%), Gaps = 90/850 (10%)
Query: 570 PVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADG 629
P RERK+SI+ IS DDL++YHRRQR+ERLREQEMERLERQRLETIL+LCAEY++ D
Sbjct: 434 PALRERKSSISSIS-GRDDLMDYHRRQREERLREQEMERLERQRLETILSLCAEYTKPDS 492
Query: 630 ----GPEAGELPSIGEATAALALAGRR----------------------PSRGLAGASGR 663
G ++ I + L L+ P LA
Sbjct: 493 RLSTGTTVEDVQKINKELEKLQLSDEESVFEEALMSPDTRYRCHRKDSLPDADLASCGSL 552
Query: 664 SSEEPGVATQRLWESMER-SDEENLKEECSST---ESTQQEH--------EDAPSTKLQG 711
S T R + E SD SST S++ + E +
Sbjct: 553 SQSSASFFTPRSTRNDELLSDLTRTPPPPSSTFPKASSESSYLSILPKTPEGISEEQRSQ 612
Query: 712 EVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQK 771
E+ A+EE R +L ++E+LK ++K++ Q+ ES RE +ME ALL GE+++E L KE++
Sbjct: 613 ELAAMEETRIVILNNLEELKQKIKDINDQMDESFRELDMECALLDGEQKSETTELMKEKE 672
Query: 772 AVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLL 831
+D L K+ LE I E+ K+A+ L+ E+K FEDLEFQQLE ESR++EE+E Q LL
Sbjct: 673 ILDHLNRKIAELEKNIVGEKTKDADLLDVESKHFEDLEFQQLEHESRLDEEKENLTQQLL 732
Query: 832 RSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLE 891
R AE R+I RKE+++ L QA I QA +E + ++KN + +LQ+EKE L LE
Sbjct: 733 REVAEYQRNIVSRKEKISALKKQANHIVQQAQREQDHFVKEKNNLIMMLQREKENLCNLE 792
Query: 892 RRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLP 951
++Y SL+GG+ FP +TLKE + + ++ ++ PA A ++ P
Sbjct: 793 KKYSSLSGGKGFPVNPNTLKE-GYISVNEINEPCGNSTNLSPSTQFPADADAVATEPATA 851
Query: 952 AKASR--QLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSAL 1009
AS+ + +RS + + S LP +SS S S AT+GRS +PK+ L
Sbjct: 852 VLASQPQSKEHFRSLEERKKQHKEGLYLSDTLPRKKTTSSISPHFSSATMGRSITPKAHL 911
Query: 1010 LT--QNGTGS-LPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQ 1066
N GS LP +LAA +D E++R L + Q + E R+ +E + A+E+
Sbjct: 912 PLGQSNSCGSVLPPSLAAMAKDSESRRML--RGYNHQQMSEGHRQKSEFYNRTASESNVY 969
Query: 1067 WDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSIST 1126
++ H +P HS + A+DTLSL+SSDSMETSIS
Sbjct: 970 LNSFH-----------YPD---HSYK-------------DQAFDTLSLDSSDSMETSIS- 1001
Query: 1127 GGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRR 1186
ACSPDN+SSAS ++ +IEEME++LK+AHAEK RL+ESREREME +++ALEEE+RR
Sbjct: 1002 ----ACSPDNISSASTSNIARIEEMERLLKQAHAEKTRLLESREREMEAKKRALEEEKRR 1057
Query: 1187 REQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGV 1246
RE +E+RLQ E+++RQ+L+EKEVK+RE+Q +QARPLTRYLP+RKEDFDL++H+E++GH +
Sbjct: 1058 REILEKRLQEETSQRQKLIEKEVKIRERQRAQARPLTRYLPVRKEDFDLRSHVETAGHNI 1117
Query: 1247 DTCLHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQA 1306
DTC HV ++ K CRG+L+KMGGKIK+WKKRWFVFDR KRT SYY DKHETKLKGVIYFQA
Sbjct: 1118 DTCYHVSITEKTCRGFLIKMGGKIKTWKKRWFVFDRNKRTFSYYADKHETKLKGVIYFQA 1177
Query: 1307 IEEVYYDHLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIV 1366
IEEVYYDHL++A K SPNP LTF VKTHDR+YYMVAPS EAMRIWMDVIV
Sbjct: 1178 IEEVYYDHLKNANK-----------SPNPLLTFSVKTHDRIYYMVAPSPEAMRIWMDVIV 1226
Query: 1367 TGAEGYTQFM 1376
TGAEGYT F+
Sbjct: 1227 TGAEGYTHFL 1236
>gi|21955172 pleckstrin homology-like domain, family B, member 2
isoform c [Homo sapiens]
Length = 1210
Score = 652 bits (1683), Expect = 0.0
Identities = 392/850 (46%), Positives = 524/850 (61%), Gaps = 90/850 (10%)
Query: 570 PVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADG 629
P RERK+SI+ IS DDL++YHRRQR+ERLREQEMERLERQRLETIL+LCAEY++ D
Sbjct: 407 PALRERKSSISSIS-GRDDLMDYHRRQREERLREQEMERLERQRLETILSLCAEYTKPDS 465
Query: 630 ----GPEAGELPSIGEATAALALAGRR----------------------PSRGLAGASGR 663
G ++ I + L L+ P LA
Sbjct: 466 RLSTGTTVEDVQKINKELEKLQLSDEESVFEEALMSPDTRYRCHRKDSLPDADLASCGSL 525
Query: 664 SSEEPGVATQRLWESMER-SDEENLKEECSST---ESTQQEH--------EDAPSTKLQG 711
S T R + E SD SST S++ + E +
Sbjct: 526 SQSSASFFTPRSTRNDELLSDLTRTPPPPSSTFPKASSESSYLSILPKTPEGISEEQRSQ 585
Query: 712 EVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQK 771
E+ A+EE R +L ++E+LK ++K++ Q+ ES RE +ME ALL GE+++E L KE++
Sbjct: 586 ELAAMEETRIVILNNLEELKQKIKDINDQMDESFRELDMECALLDGEQKSETTELMKEKE 645
Query: 772 AVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLL 831
+D L K+ LE I E+ K+A+ L+ E+K FEDLEFQQLE ESR++EE+E Q LL
Sbjct: 646 ILDHLNRKIAELEKNIVGEKTKDADLLDVESKHFEDLEFQQLEHESRLDEEKENLTQQLL 705
Query: 832 RSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLE 891
R AE R+I RKE+++ L QA I QA +E + ++KN + +LQ+EKE L LE
Sbjct: 706 REVAEYQRNIVSRKEKISALKKQANHIVQQAQREQDHFVKEKNNLIMMLQREKENLCNLE 765
Query: 892 RRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLP 951
++Y SL+GG+ FP +TLKE + + ++ ++ PA A ++ P
Sbjct: 766 KKYSSLSGGKGFPVNPNTLKE-GYISVNEINEPCGNSTNLSPSTQFPADADAVATEPATA 824
Query: 952 AKASR--QLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSAL 1009
AS+ + +RS + + S LP +SS S S AT+GRS +PK+ L
Sbjct: 825 VLASQPQSKEHFRSLEERKKQHKEGLYLSDTLPRKKTTSSISPHFSSATMGRSITPKAHL 884
Query: 1010 LT--QNGTGS-LPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQ 1066
N GS LP +LAA +D E++R L + Q + E R+ +E + A+E+
Sbjct: 885 PLGQSNSCGSVLPPSLAAMAKDSESRRML--RGYNHQQMSEGHRQKSEFYNRTASESNVY 942
Query: 1067 WDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSIST 1126
++ H +P HS + A+DTLSL+SSDSMETSIS
Sbjct: 943 LNSFH-----------YPD---HSYK-------------DQAFDTLSLDSSDSMETSIS- 974
Query: 1127 GGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRR 1186
ACSPDN+SSAS ++ +IEEME++LK+AHAEK RL+ESREREME +++ALEEE+RR
Sbjct: 975 ----ACSPDNISSASTSNIARIEEMERLLKQAHAEKTRLLESREREMEAKKRALEEEKRR 1030
Query: 1187 REQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGV 1246
RE +E+RLQ E+++RQ+L+EKEVK+RE+Q +QARPLTRYLP+RKEDFDL++H+E++GH +
Sbjct: 1031 REILEKRLQEETSQRQKLIEKEVKIRERQRAQARPLTRYLPVRKEDFDLRSHVETAGHNI 1090
Query: 1247 DTCLHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQA 1306
DTC HV ++ K CRG+L+KMGGKIK+WKKRWFVFDR KRT SYY DKHETKLKGVIYFQA
Sbjct: 1091 DTCYHVSITEKTCRGFLIKMGGKIKTWKKRWFVFDRNKRTFSYYADKHETKLKGVIYFQA 1150
Query: 1307 IEEVYYDHLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIV 1366
IEEVYYDHL++A K SPNP LTF VKTHDR+YYMVAPS EAMRIWMDVIV
Sbjct: 1151 IEEVYYDHLKNANK-----------SPNPLLTFSVKTHDRIYYMVAPSPEAMRIWMDVIV 1199
Query: 1367 TGAEGYTQFM 1376
TGAEGYT F+
Sbjct: 1200 TGAEGYTHFL 1209
>gi|197313732 pleckstrin homology-like domain, family B, member 2
isoform a [Homo sapiens]
Length = 1253
Score = 633 bits (1632), Expect = 0.0
Identities = 393/893 (44%), Positives = 524/893 (58%), Gaps = 133/893 (14%)
Query: 570 PVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADG 629
P RERK+SI+ IS DDL++YHRRQR+ERLREQEMERLERQRLETIL+LCAEY++ D
Sbjct: 407 PALRERKSSISSIS-GRDDLMDYHRRQREERLREQEMERLERQRLETILSLCAEYTKPDS 465
Query: 630 ----GPEAGELPSIGEATAALALAGRR----------------------PSRGLAGASGR 663
G ++ I + L L+ P LA
Sbjct: 466 RLSTGTTVEDVQKINKELEKLQLSDEESVFEEALMSPDTRYRCHRKDSLPDADLASCGSL 525
Query: 664 SSEEPGVATQRLWESMER-SDEENLKEECSST---ESTQQEH--------EDAPSTKLQG 711
S T R + E SD SST S++ + E +
Sbjct: 526 SQSSASFFTPRSTRNDELLSDLTRTPPPPSSTFPKASSESSYLSILPKTPEGISEEQRSQ 585
Query: 712 EVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQK 771
E+ A+EE R +L ++E+LK ++K++ Q+ ES RE +ME ALL GE+++E L KE++
Sbjct: 586 ELAAMEETRIVILNNLEELKQKIKDINDQMDESFRELDMECALLDGEQKSETTELMKEKE 645
Query: 772 AVDQLQEKLVALETGIQKERDKE------------------------------------- 794
+D L K+ LE I E+ KE
Sbjct: 646 ILDHLNRKIAELEKNIVGEKTKEKVKLDAEREKLERLQELYSEQKTQLDNCPESMREQLQ 705
Query: 795 ------AEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERL 848
A+ L+ E+K FEDLEFQQLE ESR++EE+E Q LLR AE R+I RKE++
Sbjct: 706 QQLKRDADLLDVESKHFEDLEFQQLEHESRLDEEKENLTQQLLREVAEYQRNIVSRKEKI 765
Query: 849 AILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTS 908
+ L QA I QA +E + ++KN + +LQ+EKE L LE++Y SL+GG+ FP +
Sbjct: 766 SALKKQANHIVQQAQREQDHFVKEKNNLIMMLQREKENLCNLEKKYSSLSGGKGFPVNPN 825
Query: 909 TLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASR--QLQVYRSKMD 966
TLKE + + ++ ++ PA A ++ P AS+ + +RS +
Sbjct: 826 TLKE-GYISVNEINEPCGNSTNLSPSTQFPADADAVATEPATAVLASQPQSKEHFRSLEE 884
Query: 967 GEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLT--QNGTGS-LPRNLA 1023
+ S LP +SS S S AT+GRS +PK+ L N GS LP +LA
Sbjct: 885 RKKQHKEGLYLSDTLPRKKTTSSISPHFSSATMGRSITPKAHLPLGQSNSCGSVLPPSLA 944
Query: 1024 ATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGF 1083
A +D E++R L + Q + E R+ +E + A+E+ ++ H +
Sbjct: 945 AMAKDSESRRML--RGYNHQQMSEGHRQKSEFYNRTASESNVYLNSFH-----------Y 991
Query: 1084 PPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGL 1143
P HS + A+DTLSL+SSDSMETSIS ACSPDN+SSAS
Sbjct: 992 PD---HSYK-------------DQAFDTLSLDSSDSMETSIS-----ACSPDNISSASTS 1030
Query: 1144 DMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQ 1203
++ +IEEME++LK+AHAEK RL+ESREREME +++ALEEE+RRRE +E+RLQ E+++RQ+
Sbjct: 1031 NIARIEEMERLLKQAHAEKTRLLESREREMEAKKRALEEEKRRREILEKRLQEETSQRQK 1090
Query: 1204 LVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYL 1263
L+EKEVK+RE+Q +QARPLTRYLP+RKEDFDL++H+E++GH +DTC HV ++ K CRG+L
Sbjct: 1091 LIEKEVKIRERQRAQARPLTRYLPVRKEDFDLRSHVETAGHNIDTCYHVSITEKTCRGFL 1150
Query: 1264 VKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAKKRF 1323
+KMGGKIK+WKKRWFVFDR KRT SYY DKHETKLKGVIYFQAIEEVYYDHL++A K
Sbjct: 1151 IKMGGKIKTWKKRWFVFDRNKRTFSYYADKHETKLKGVIYFQAIEEVYYDHLKNANK--- 1207
Query: 1324 FRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFM 1376
SPNP LTF VKTHDR+YYMVAPS EAMRIWMDVIVTGAEGYT F+
Sbjct: 1208 --------SPNPLLTFSVKTHDRIYYMVAPSPEAMRIWMDVIVTGAEGYTHFL 1252
>gi|197313730 pleckstrin homology-like domain, family B, member 2
isoform a [Homo sapiens]
Length = 1253
Score = 633 bits (1632), Expect = 0.0
Identities = 393/893 (44%), Positives = 524/893 (58%), Gaps = 133/893 (14%)
Query: 570 PVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADG 629
P RERK+SI+ IS DDL++YHRRQR+ERLREQEMERLERQRLETIL+LCAEY++ D
Sbjct: 407 PALRERKSSISSIS-GRDDLMDYHRRQREERLREQEMERLERQRLETILSLCAEYTKPDS 465
Query: 630 ----GPEAGELPSIGEATAALALAGRR----------------------PSRGLAGASGR 663
G ++ I + L L+ P LA
Sbjct: 466 RLSTGTTVEDVQKINKELEKLQLSDEESVFEEALMSPDTRYRCHRKDSLPDADLASCGSL 525
Query: 664 SSEEPGVATQRLWESMER-SDEENLKEECSST---ESTQQEH--------EDAPSTKLQG 711
S T R + E SD SST S++ + E +
Sbjct: 526 SQSSASFFTPRSTRNDELLSDLTRTPPPPSSTFPKASSESSYLSILPKTPEGISEEQRSQ 585
Query: 712 EVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQK 771
E+ A+EE R +L ++E+LK ++K++ Q+ ES RE +ME ALL GE+++E L KE++
Sbjct: 586 ELAAMEETRIVILNNLEELKQKIKDINDQMDESFRELDMECALLDGEQKSETTELMKEKE 645
Query: 772 AVDQLQEKLVALETGIQKERDKE------------------------------------- 794
+D L K+ LE I E+ KE
Sbjct: 646 ILDHLNRKIAELEKNIVGEKTKEKVKLDAEREKLERLQELYSEQKTQLDNCPESMREQLQ 705
Query: 795 ------AEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERL 848
A+ L+ E+K FEDLEFQQLE ESR++EE+E Q LLR AE R+I RKE++
Sbjct: 706 QQLKRDADLLDVESKHFEDLEFQQLEHESRLDEEKENLTQQLLREVAEYQRNIVSRKEKI 765
Query: 849 AILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTS 908
+ L QA I QA +E + ++KN + +LQ+EKE L LE++Y SL+GG+ FP +
Sbjct: 766 SALKKQANHIVQQAQREQDHFVKEKNNLIMMLQREKENLCNLEKKYSSLSGGKGFPVNPN 825
Query: 909 TLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASR--QLQVYRSKMD 966
TLKE + + ++ ++ PA A ++ P AS+ + +RS +
Sbjct: 826 TLKE-GYISVNEINEPCGNSTNLSPSTQFPADADAVATEPATAVLASQPQSKEHFRSLEE 884
Query: 967 GEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLT--QNGTGS-LPRNLA 1023
+ S LP +SS S S AT+GRS +PK+ L N GS LP +LA
Sbjct: 885 RKKQHKEGLYLSDTLPRKKTTSSISPHFSSATMGRSITPKAHLPLGQSNSCGSVLPPSLA 944
Query: 1024 ATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGF 1083
A +D E++R L + Q + E R+ +E + A+E+ ++ H +
Sbjct: 945 AMAKDSESRRML--RGYNHQQMSEGHRQKSEFYNRTASESNVYLNSFH-----------Y 991
Query: 1084 PPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGL 1143
P HS + A+DTLSL+SSDSMETSIS ACSPDN+SSAS
Sbjct: 992 PD---HSYK-------------DQAFDTLSLDSSDSMETSIS-----ACSPDNISSASTS 1030
Query: 1144 DMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQ 1203
++ +IEEME++LK+AHAEK RL+ESREREME +++ALEEE+RRRE +E+RLQ E+++RQ+
Sbjct: 1031 NIARIEEMERLLKQAHAEKTRLLESREREMEAKKRALEEEKRRREILEKRLQEETSQRQK 1090
Query: 1204 LVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVDTCLHVVLSSKVCRGYL 1263
L+EKEVK+RE+Q +QARPLTRYLP+RKEDFDL++H+E++GH +DTC HV ++ K CRG+L
Sbjct: 1091 LIEKEVKIRERQRAQARPLTRYLPVRKEDFDLRSHVETAGHNIDTCYHVSITEKTCRGFL 1150
Query: 1264 VKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLKGVIYFQAIEEVYYDHLRSAAKKRF 1323
+KMGGKIK+WKKRWFVFDR KRT SYY DKHETKLKGVIYFQAIEEVYYDHL++A K
Sbjct: 1151 IKMGGKIKTWKKRWFVFDRNKRTFSYYADKHETKLKGVIYFQAIEEVYYDHLKNANK--- 1207
Query: 1324 FRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVIVTGAEGYTQFM 1376
SPNP LTF VKTHDR+YYMVAPS EAMRIWMDVIVTGAEGYT F+
Sbjct: 1208 --------SPNPLLTFSVKTHDRIYYMVAPSPEAMRIWMDVIVTGAEGYTHFL 1252
>gi|157266264 pleckstrin homology-like domain, family B, member 3
[Homo sapiens]
Length = 640
Score = 205 bits (522), Expect = 2e-52
Identities = 214/734 (29%), Positives = 299/734 (40%), Gaps = 145/734 (19%)
Query: 678 SMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKEL 737
S E L EC E Q H + + EVLA R G EQ +
Sbjct: 6 SPEEGTPPPLVPECD-VEVQPQGHPEESREQEASEVLAEPSSR----GGAEQQAEEEEVG 60
Query: 738 EQQLQESAREAEMERALLQGEREAERALLQKE--QKAVDQLQEKLVALETGIQKERDKEA 795
E ES+R+A + + +E + A +LQ G Q E
Sbjct: 61 EGSSTESSRDAPEATPPIAMAATPPASTSSREGVRGAARRLQ--------GQQLEALTRV 112
Query: 796 EALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQA 855
+E K E Q+ +E R+E E E+A LLR + R A+R+E Q
Sbjct: 113 ALMEQRVK-----ELQRQRKELRIEMEVEVA---LLRGELAGERVAARREEE------QL 158
Query: 856 GQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEK 915
++ Q +R + + + L +E+++L L +R G + S ++ +
Sbjct: 159 RELLEQQAASEQRGRQQREQEQRRLSQERDRLEGLRQRLRKAQG-----QLDSQPEDQRE 213
Query: 916 LLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPR 975
LL V QE+ L +A L+ + + +
Sbjct: 214 RLLQGV------QEMREQLDVAQ--------------RAYEDLEFQQLERESRQEE---E 250
Query: 976 TRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQL 1035
R P P Q S+A R + + SL +AA + + K++
Sbjct: 251 DRDSPGPQVPDPKVQELQASMAQHRRGALQHRIRVLEEQLKSLGEQMAAESRGLSRKKEE 310
Query: 1036 ALQQKGQQVIEEQRRRLAELK-----------------------QKAAAEAQCQWDALHG 1072
ALQ + ++R RL EL QK + DA+
Sbjct: 311 ALQ-----ALSQERSRLLELNCLQGTPGGDFSEPNPALTKLLFTQKTDRQLLVLQDAVAH 365
Query: 1073 AAPFPAGPSGFPPLMHHSILHHL------PAGRERGEEGEHAYDT--LSLESSDSMETSI 1124
+A P F +H S+ + R+RGE G LS ++S+E S
Sbjct: 366 SAATPTSSCLFS--VHSSLQGSIGLQRTGSLPRKRGERGSQRGSPRPLSFHCTESLEASA 423
Query: 1125 --STGGNSACSP--DNMSSASGLDMGKIE----EMEKMLKEAHAEKNRLMESREREMELR 1176
G+S P ++ G G I ME++L++A AE+ RL+++RE
Sbjct: 424 LPPAVGDSGRYPLYQLLNCGRGNSCGAIHPDIAHMERLLQQAMAERERLLKAREG----- 478
Query: 1177 RQALEEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLK 1236
R + S + P T P DL+
Sbjct: 479 -------------TRRGTEGSSGPAVPAI-------------TAPPTPPHPPGPRILDLR 512
Query: 1237 THIESSGHGVDTCLHVVLSSKVCRGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHET 1296
H+E GH + C HV +S CRG LVKMGG+IK+W+KRWF FDR R L+YY DK ET
Sbjct: 513 QHLEGWGHNPENCPHVQVSGCCCRGPLVKMGGRIKTWRKRWFCFDRQARRLAYYADKEET 572
Query: 1297 KLKGVIYFQAIEEVYYDHLRSAAKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAE 1356
KLKGVIYFQAIEEVYYDHLR A K SPNP LTFCVKT++RL+YMVAPS E
Sbjct: 573 KLKGVIYFQAIEEVYYDHLRCAFK-----------SPNPRLTFCVKTYERLFYMVAPSPE 621
Query: 1357 AMRIWMDVIVTGAE 1370
AMRIWMDVIVT A+
Sbjct: 622 AMRIWMDVIVTAAD 635
Score = 45.4 bits (106), Expect = 4e-04
Identities = 69/292 (23%), Positives = 120/292 (41%), Gaps = 46/292 (15%)
Query: 601 LREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGA 660
L EQ ++ L+RQR E + + E + GEL GE AA RR L
Sbjct: 114 LMEQRVKELQRQRKELRIEMEVEVALL-----RGELA--GERVAA-----RREEEQL--- 158
Query: 661 SGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLAL-EEE 719
R E A+++ ++ L +E E +Q K QG++ + E++
Sbjct: 159 --RELLEQQAASEQRGRQQREQEQRRLSQERDRLEGLRQRLR-----KAQGQLDSQPEDQ 211
Query: 720 RAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEK 779
R ++L V++++ ++ ++ Q+ E ++ER Q E + + Q V +LQ
Sbjct: 212 RERLLQGVQEMREQL-DVAQRAYEDLEFQQLERESRQEEEDRDSPGPQVPDPKVQELQAS 270
Query: 780 LVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLR 839
+ G + R LE + K +Q+ ESR GL R K E L+
Sbjct: 271 MAQHRRGALQHR---IRVLEEQLKSLG----EQMAAESR----------GLSRKKEEALQ 313
Query: 840 SIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLE 891
++++ + RL L+ G + + L + L QK +L VL+
Sbjct: 314 ALSQERSRLLELNCLQGTPGGDFSEPNPALTK-----LLFTQKTDRQLLVLQ 360
Score = 37.0 bits (84), Expect = 0.13
Identities = 48/182 (26%), Positives = 74/182 (40%), Gaps = 28/182 (15%)
Query: 594 RRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRP 653
+R RQ+R +EQ ER RLE + R G+L S E L G +
Sbjct: 170 QRGRQQREQEQRRLSQERDRLEGL--------RQRLRKAQGQLDSQPEDQRERLLQGVQE 221
Query: 654 SRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEV 713
R E+ VA QR +E +E E +E E P K+Q
Sbjct: 222 MR----------EQLDVA-QRAYEDLEFQQLE--RESRQEEEDRDSPGPQVPDPKVQELQ 268
Query: 714 LALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEME-RALLQGEREAERALLQKEQKA 772
++ + R L H R++ LE+QL+ + E R L + + EA +AL Q+ +
Sbjct: 269 ASMAQHRRGALQH------RIRVLEEQLKSLGEQMAAESRGLSRKKEEALQALSQERSRL 322
Query: 773 VD 774
++
Sbjct: 323 LE 324
>gi|41327691 kinesin-like motor protein C20orf23 [Homo sapiens]
Length = 1317
Score = 99.8 bits (247), Expect = 2e-20
Identities = 52/140 (37%), Positives = 84/140 (60%), Gaps = 5/140 (3%)
Query: 14 QTQTMVQKGPLDLIETGKGLKVQTDKPHLVSLGSGRLSTAITLLPLEEGRTVIG----SA 69
+TQ ++++ L L + G G+ + ++ PHL+ + LST I L L+EG+T +G S
Sbjct: 428 ETQNILKEQTLALRKEGIGVVLDSELPHLIGIDDDLLSTGIILYHLKEGQTYVGRDDAST 487
Query: 70 ARDISLQGPGLAPEHCYIENLRGTLTLYPC-GNACTIDGLPVRQPTRLTQGCMLCLGQST 128
+DI L G L EHC EN+ GT+TL P G+ C+++G+ + + T L QG ++ LG++
Sbjct: 488 EQDIVLHGLDLESEHCIFENIGGTVTLIPLSGSQCSVNGVQIVEATHLNQGAVILLGRTN 547
Query: 129 FLRFNHPAEAKWMKSMIPAG 148
RFNHP EA ++ +G
Sbjct: 548 MFRFNHPKEAAKLREKRKSG 567
Score = 47.0 bits (110), Expect = 1e-04
Identities = 77/356 (21%), Positives = 158/356 (44%), Gaps = 50/356 (14%)
Query: 578 SITEISDNEDDL---------LEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRAD 628
S+T++S + ++L LE+ R+QR+E + + +L + E + AE R
Sbjct: 575 SMTDLSKSRENLSAVMLYNPGLEFERQQREELEKLESKRKLIEEMEEKQKSDKAELERMQ 634
Query: 629 GGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLK 688
E+ + + T + L R+ L S + + L E+ +EE L+
Sbjct: 635 Q-----EVETQRKETEIVQLQIRKQEESLKRRSFHIENK----LKDLLAEKEKFEEERLR 685
Query: 689 EECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREA 748
E QQE E + + L ++EE R+KEL + +
Sbjct: 686 E--------QQEIELQKKRQEEETFLRVQEELQ-----------RLKELNNNEKAEKFQI 726
Query: 749 EMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALET----ETKL 804
E LQ E++ + A L+ E+K +++ +++ V L ++++ ++ E ++ E +
Sbjct: 727 FQELDQLQKEKDEQYAKLELEKKRLEEQEKEQVMLVAHLEEQLREKQEMIQLLRRGEVQW 786
Query: 805 FEDLEFQQLE--RESRVEEERELAG---QGLLRSKAELLRSIAKRKERLAILDSQAGQIR 859
E+ E + LE RES + + AG G KA+L KR++ + +++ + ++
Sbjct: 787 VEE-EKRDLEGIRESLLRVKEARAGGDEDGEELEKAQLRFFEFKRRQLVKLVNLEKDLVQ 845
Query: 860 AQAVQESERLARDKNASLQLLQKEKEKLT-VLERRYHSLTGGRPFPKTTSTLKEME 914
+ + + E +++ L+ L+ E +K + +LE+ S+T P+ +K +E
Sbjct: 846 QKDILKKE--VQEEQEILECLKCEHDKESRLLEKHDESVTDVTEVPQDFEKIKPVE 899
Score = 43.1 bits (100), Expect = 0.002
Identities = 52/232 (22%), Positives = 103/232 (44%), Gaps = 16/232 (6%)
Query: 578 SITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELP 637
S+T++++ D + + + + +E++++ L + L T+L E RA + G L
Sbjct: 881 SVTDVTEVPQDFEKIKPVEYRLQYKERQLQYLLQNHLPTLLE---EKQRAFEILDRGPL- 936
Query: 638 SIGEATAALALAGRRPSRGLAGASGRSSEEPGV-ATQRLWESMERSDEENLKEECSSTES 696
S+ + LA +++ + AT ++ R +E+ K+E ES
Sbjct: 937 SLDNTLYQVEKEMEEKEEQLAQYQANANQLQKLQATFEFTANIARQEEKVRKKEKEILES 996
Query: 697 TQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQ 756
+++ +A LA E R L L + ++E Q+L S E++ LQ
Sbjct: 997 REKQQREALE-----RALARLERRHSALQRHSTLGMEIEEQRQKLA-SLNSGSREQSGLQ 1050
Query: 757 GEREAERALLQKEQK----AVDQLQEKLVALETGIQKERDKEAEALETETKL 804
EAE+ L+K+Q+ + QL++K+ ++ G+QK+ E + L
Sbjct: 1051 ASLEAEQEALEKDQERLEYEIQQLKQKIYEVD-GVQKDHHGTLEGKVASSSL 1101
Score = 31.2 bits (69), Expect = 7.2
Identities = 23/75 (30%), Positives = 42/75 (56%), Gaps = 9/75 (12%)
Query: 1148 IEEMEKMLKEAHAEKNRL---MESREREMEL----RRQALEEERRRREQVERRLQSESAR 1200
IEEME+ K AE R+ +E++ +E E+ R+ E +RR +E +L+ A
Sbjct: 616 IEEMEEKQKSDKAELERMQQEVETQRKETEIVQLQIRKQEESLKRRSFHIENKLKDLLAE 675
Query: 1201 RQQLVEKEVKMREKQ 1215
+++ +E ++RE+Q
Sbjct: 676 KEKF--EEERLREQQ 688
>gi|4505939 DNA-directed RNA polymerase II A [Homo sapiens]
Length = 1970
Score = 75.9 bits (185), Expect = 3e-13
Identities = 109/420 (25%), Positives = 155/420 (36%), Gaps = 46/420 (10%)
Query: 145 IPAGGRAPGPPYSPVPAESESLVNGNHTPQTATRGPSACASHSSLVSSIEKDLQEIMDSL 204
IP+ G A P YSP E G +TPQ+ + P++ S+S S +
Sbjct: 1582 IPSPGGAMSPSYSPTSPAYEPRSPGGYTPQSPSYSPTS-PSYSPTSPSYSPTSPNYSPTS 1640
Query: 205 VLEEPGAAGKKPAAT--SPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPA 262
P + P + SP SP + PTSP SY TSP++SP +SP+
Sbjct: 1641 PSYSPTSPSYSPTSPSYSPTSPSYS--------PTSPSYSPTSPSYSPTSPSYSP-TSPS 1691
Query: 263 SSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPSGARS-ESPRLSRKGGHER 321
S + S+SP+ P+ P P +S + P S S + S SP S +
Sbjct: 1692 YSPTSPSYSPTSPSYSPTSPSYSP--TSPSYSPTSPSYSPTSPSYSPTSPSYSPTSPNYS 1749
Query: 322 PPSPGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVAISLSEYPASGALSQPTS---I 378
P SP SP+ + + + T SP P + + Y + PTS
Sbjct: 1750 PTSP---NYTPTSPSYSPTSPSYSPT-SPNYTPTSPNYSPTSPSYSPTSPSYSPTSPSYS 1805
Query: 379 PGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSPSRQLVGRTFSDGLATRTL 438
P SP++ P P PS P S TSP ++S T
Sbjct: 1806 PSSPRYTPQSPT----------YTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEYTP 1855
Query: 439 QPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPTRTTPDPKLNREVAESPR--PRRWA 496
P+ + + + P SP+ S PT T P SP+ P
Sbjct: 1856 TSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTSPT 1915
Query: 497 AHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGSFSGRLSPAYSLGSLTGASPCQSP 556
SP+ +S T T SP+ G + +P +S SP YSL SP SP
Sbjct: 1916 YSPTSPK-YSPT-----SPTYSPTSPKGSTYSPTSPGYS-PTSPTYSL-----TSPAISP 1963
Score = 62.4 bits (150), Expect = 3e-09
Identities = 85/297 (28%), Positives = 109/297 (36%), Gaps = 36/297 (12%)
Query: 209 PGAAGKKPAATSPLSPMANGGRYLLSP-PTSPGAMSVGSSYENT-----SPAFSPLS--- 259
PGAAG P+A S S + G SP P SPG+ S Y + SP++SP S
Sbjct: 1541 PGAAGFSPSAASDASGFSPGYSPAWSPTPGSPGSPGPSSPYIPSPGGAMSPSYSPTSPAY 1600
Query: 260 SPASSGSCASHSPSGQEPGPSVPPLVPARS--SSYHLALQPPQSRPSGARS-ESPRLSRK 316
P S G SPS PS P P+ S S + P S S + S SP S
Sbjct: 1601 EPRSPGGYTPQSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPT 1660
Query: 317 GGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVAISLSEYPASGALSQPT 376
P SP SP+ + + + T SP P + + Y + PT
Sbjct: 1661 SPSYSPTSPSYS---PTSPSYSPTSPSYSPT-SPSYSPTSPSYSPTSPSYSPTSPSYSPT 1716
Query: 377 S---IPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSPSRQLVGRTFSDGL 433
S P SP + P P + T P+ P S TSPS ++S
Sbjct: 1717 SPSYSPTSPSYSPTSP---SYSPTSPSYSPTSPNYSPTSPNYTPTSPSYSPTSPSYS--- 1770
Query: 434 ATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPTRTTPDPKLNREVAESP 490
T P SP P SPS S + S PT + P R +SP
Sbjct: 1771 PTSPNYTPTSPNYS-----------PTSPSYSPTSPSYSPTSPSYSPSSPRYTPQSP 1816
Score = 52.8 bits (125), Expect = 2e-06
Identities = 90/349 (25%), Positives = 125/349 (35%), Gaps = 37/349 (10%)
Query: 213 GKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPASSGSCASHSP 272
G P+ +SP +P + SVGS + FSP ++ +SG +SP
Sbjct: 1504 GSAPSPMGGISPAMTPWNQGATPAYGAWSPSVGSGMTPGAAGFSPSAASDASGFSPGYSP 1563
Query: 273 SGQEPGPSVPPLVPARSSSYHLALQPPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLT 332
+ P P P P SS Y PS + SP S P SPG G
Sbjct: 1564 A-WSPTPGSPG-SPGPSSPY---------IPSPGGAMSPSYSPTSPAYEPRSPG--GYTP 1610
Query: 333 DSPAATVLAEARRATESPRLGGQLPVVAISLSEYPASGALSQPTS---IPGSPKFQPPVP 389
SP+ + + + T SP P + + Y + PTS P SP + P P
Sbjct: 1611 QSPSYSPTSPSYSPT-SPSYSPTSPNYSPTSPSYSPTSPSYSPTSPSYSPTSPSYSPTSP 1669
Query: 390 APRNKIGTLQDRPPSPFREPPGSERVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRR 449
+ + PS P S TSPS ++S T P SP
Sbjct: 1670 SYSPTSPSYSPTSPS---YSPTSPSYSPTSPSYSPTSPSYS---PTSPSYSPTSPSYS-- 1721
Query: 450 GLDSMRELPPLSPSLSRRALSPLPTRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTL 509
+ P SPS S + S PT P SP ++ + +S T
Sbjct: 1722 --PTSPSYSPTSPSYSPTSPSYSPTSPNYSPTSPNYTPTSP------SYSPTSPSYSPTS 1773
Query: 510 GARGRRTRSPSPTLGESLAPHKGSFSGRLSPAYSLGS--LTGASPCQSP 556
+ + SPT S +P S+S SP+YS S T SP +P
Sbjct: 1774 PNYTPTSPNYSPT-SPSYSPTSPSYS-PTSPSYSPSSPRYTPQSPTYTP 1820
Score = 32.0 bits (71), Expect = 4.2
Identities = 49/179 (27%), Positives = 66/179 (36%), Gaps = 38/179 (21%)
Query: 154 PPYSPVPAESESLVNGNHTPQTATRGPSACASHSSLVS-------------SIEKDLQEI 200
P YSP + S S + +TPQ+ T PS+ + S S S E
Sbjct: 1795 PSYSPT-SPSYSPSSPRYTPQSPTYTPSSPSYSPSSPSYSPTSPKYTPTSPSYSPSSPEY 1853
Query: 201 MDSLVLEEPGAAGKKPAAT--SPLSPMANGGRYLLSP-------------PTSPGAMSVG 245
+ P + P + SP SP + SP PTSP
Sbjct: 1854 TPTSPKYSPTSPKYSPTSPKYSPTSPTYSPTTPKYSPTSPTYSPTSPVYTPTSPKYSPTS 1913
Query: 246 SSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHL---ALQPPQS 301
+Y TSP +SP +SP S + SP G P+ P P S +Y L A+ P S
Sbjct: 1914 PTYSPTSPKYSP-TSPTYSPT----SPKGSTYSPTSPGYSPT-SPTYSLTSPAISPDDS 1966
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 75.9 bits (185), Expect = 3e-13
Identities = 84/327 (25%), Positives = 146/327 (44%), Gaps = 30/327 (9%)
Query: 573 RERKNSITEISDNEDDLLEYHRRQRQE----RLREQEMERLERQRLETILNLCAEYSRAD 628
+ER+ + E + + LE RQR++ R R++ ER ER+ E L C
Sbjct: 144 QERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCK------ 197
Query: 629 GGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQ-----RLWESMERSD 683
G E E P + L RR R R ++ + R E++ R +
Sbjct: 198 -GHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKE 256
Query: 684 EENLKEECSSTESTQQEHEDAPSTKLQGEVLALE----EERAQVLGHVEQLKVRVKELEQ 739
EE L+EE + QE E+ KL+ + L E E++ Q L +QL+ + +E +
Sbjct: 257 EEKLQEEEPQRQRELQEEEEQ-LRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERR 315
Query: 740 QLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALE 799
+ QE RE + ER Q ER ++ ++E++ QL+ + Q R++E E E
Sbjct: 316 EQQEERRE-QQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERRE 374
Query: 800 TETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIR 859
+ + QQL RE ++ E++L + LR + +L R R+E+ + Q+R
Sbjct: 375 QQLR-----REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL---RREQQLR 426
Query: 860 AQAVQESERLARDKNASLQLLQKEKEK 886
+ +E ++ Q L++E+E+
Sbjct: 427 REQEEERHEQKHEQERREQRLKREQEE 453
Score = 65.9 bits (159), Expect = 3e-10
Identities = 68/314 (21%), Positives = 135/314 (42%), Gaps = 12/314 (3%)
Query: 575 RKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAG 634
R+ + E+ + + RR+RQ+R+ ++E E+ R+R ET+L E + +
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKR-ETVLRKEEEKLQEEEPQRQR 269
Query: 635 ELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSST 694
EL E L R R EE R + + R EE +E+
Sbjct: 270 ELQEEEEQLRKLERQELRRER--------QEEEQQQQRLRREQQLRRKQEEERREQQEER 321
Query: 695 ESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERAL 754
Q+ E + Q EE R Q L ++ + R ++L ++ +E RE ++ R
Sbjct: 322 REQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ 381
Query: 755 LQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERD--KEAEALETETKLFEDLEFQQ 812
Q RE + Q+ ++ +E+ + E +++E+ +E + + + + + +Q
Sbjct: 382 -QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQ 440
Query: 813 LERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARD 872
RE R++ E+E L R + +RK++L + + R ++E ER +
Sbjct: 441 ERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQ 500
Query: 873 KNASLQLLQKEKEK 886
+ QL ++++E+
Sbjct: 501 ERREQQLRREQEER 514
Score = 64.3 bits (155), Expect = 8e-10
Identities = 138/682 (20%), Positives = 250/682 (36%), Gaps = 76/682 (11%)
Query: 575 RKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAG 634
RK E+ + RR++QE REQ++ R + +R E L E R +
Sbjct: 308 RKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRRE 367
Query: 635 ELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSST 694
+ E RR + R ++ Q E R +++ +E+
Sbjct: 368 QEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRR 427
Query: 695 ESTQQEHEDAPSTKLQGEVLALE-EERAQVLGHVEQLKVRVKELEQQLQESAREAEMERA 753
E ++ HE + + + L E EER L E+ + +E +Q + +E E
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 754 LLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQL 813
L+ E E R ++ ++ + + QE+ Q+E ++ + L +E +L + E ++
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQE-ERR 546
Query: 814 ERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDK 873
E+ + EEE+ L + R + L R +R+++L + + Q R + QE ERL +
Sbjct: 547 EQLLKREEEKRLEQE---RREQRLKREQEERRDQLLKREEERRQQRLKREQE-ERLEQ-- 600
Query: 874 NASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAG 933
+L ++E E+L ERR L K +E + LL + + E+ Q+ +
Sbjct: 601 ----RLKREEVERLEQEERREQRL-------KREEPEEERRQQLLKSEEQEERRQQQLRR 649
Query: 934 LGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQ 993
+ R+ ++ R + + L R + Q
Sbjct: 650 -----------------EQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQ 692
Query: 994 LSVATLGRSPS-----PKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQ 1048
R P A Q+ S PR + E + + ++ Q EE+
Sbjct: 693 ARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEE 752
Query: 1049 RRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILH------------HLP 1096
R + +++ + QW A + S PPL LP
Sbjct: 753 RAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLP 812
Query: 1097 AGRE----RGEEGEHAYDTLSLESSDSMET-------SISTGGNSACSPDNMSSASGLDM 1145
E R + E + LE + ++ G S D
Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872
Query: 1146 G---KIEEMEKMLKEAHAEKNRLMESREREMELRRQALEE------ERRRREQVERRLQS 1196
++EE K + K L E +E +L ++ EE E+RRR++ ER+ +
Sbjct: 873 KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYRE 932
Query: 1197 ESARRQ---QLVEKEVKMREKQ 1215
E +Q QL+ +E + R +Q
Sbjct: 933 EEQLQQEEEQLLREEREKRRRQ 954
Score = 63.5 bits (153), Expect = 1e-09
Identities = 140/682 (20%), Positives = 251/682 (36%), Gaps = 78/682 (11%)
Query: 559 QRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETIL 618
QR LR ER+ E + ++ + R+ Q+ REQE R ++ R E
Sbjct: 298 QRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE 357
Query: 619 NLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWES 678
+ R + E E E RR + L E+ Q+L
Sbjct: 358 ERREQQLRREQEEERREQQLRREQQLRREQQLRREQQ-LRREQQLRREQQLRREQQLRRE 416
Query: 679 MERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELE 738
+ E+ L+ E Q+ ++ +L+ E +EER L E+ + +E
Sbjct: 417 QQLRREQQLRREQEEERHEQKHEQERREQRLKRE----QEERRDWLKREEETERHEQERR 472
Query: 739 QQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEAL 798
+Q + +E E L+ E E R ++ ++ + + QE+ Q+E ++ + L
Sbjct: 473 KQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRL 532
Query: 799 ETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQI 858
+E +L + E ++ E+ + EEE+ L + R + L R +R+++L + + Q
Sbjct: 533 RSEQQLRREQE-ERREQLLKREEEKRLEQE---RREQRLKREQEERRDQLLKREEERRQQ 588
Query: 859 RAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLL 918
R + QE ERL + +L ++E E+L ERR L K +E + LL
Sbjct: 589 RLKREQE-ERLEQ------RLKREEVERLEQEERREQRL-------KREEPEEERRQQLL 634
Query: 919 PAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRS 978
+ + E+ Q+ + + R+ ++ R + + L R
Sbjct: 635 KSEEQEERRQQQLR-----------------REQQERREQRLKREEEEERLEQRLKREHE 677
Query: 979 GPLPSSSGSSSSSSQLSVATLGRSPS-----PKSALLTQNGTGSLPRNLAATLQDIETKR 1033
+ Q R P A Q+ S PR + E +
Sbjct: 678 EERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEE 737
Query: 1034 QLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILH 1093
+ ++ Q EE+R + +++ + QW A + S PPL
Sbjct: 738 KRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQ---- 793
Query: 1094 HLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEK 1153
RER L E E ++ +EE E+
Sbjct: 794 -----RER---------QLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQ 839
Query: 1154 MLKEAHA-----EKNRLMESRE--REMELRRQ-----ALEEERRRREQ---VERRLQSES 1198
+ + A E++ L E +E R E RR LEEER+RR + LQ +
Sbjct: 840 LQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQL 899
Query: 1199 ARRQQLVEKEVKMREKQFSQAR 1220
+ QQL+++E + +++ + R
Sbjct: 900 RKEQQLLQEEEEELQREEREKR 921
Score = 58.2 bits (139), Expect = 5e-08
Identities = 88/372 (23%), Positives = 150/372 (40%), Gaps = 44/372 (11%)
Query: 591 EYHRRQRQERLREQEMERLERQRLET------ILNLCAEYSRADGGPEAGELPSIGEATA 644
E RR+R+ L+ QE ER RQ+ E AE G P + E
Sbjct: 736 EEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRE 795
Query: 645 ALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDE----------------ENLK 688
A R R R E QR + ER E + L+
Sbjct: 796 RQLRAEERQQR-----EQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQ 850
Query: 689 EECSSTESTQQEHEDAPSTKLQGEVLALEEERAQ---VLGHVEQLKVRVKELEQQLQESA 745
EE + Q+ + Q LEEER + L L+ ++++ +Q LQE
Sbjct: 851 EEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEE 910
Query: 746 REAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLF 805
E + E + +E ER ++EQ + Q +E+L+ E +K R +E E + K
Sbjct: 911 EELQREEREKRRRQEQERQYREEEQ--LQQEEEQLLREER--EKRRRQERERQYRKDKKL 966
Query: 806 EDLEFQQL----ERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQ 861
+ E Q L E+ R E E++ + L+ + E L + K R + Q + + +
Sbjct: 967 QQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRK-KDE 1025
Query: 862 AVQESERLARDKNASLQLLQKEKE--KLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLP 919
QE E+L R++ +L ++E++ + L++ L G + T +E+E+
Sbjct: 1026 LQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEE---RETRRRQELERQYRK 1082
Query: 920 AVDLEQWYQELM 931
+L+Q ++L+
Sbjct: 1083 EEELQQEEEQLL 1094
Score = 57.0 bits (136), Expect = 1e-07
Identities = 90/395 (22%), Positives = 156/395 (39%), Gaps = 54/395 (13%)
Query: 573 RERK-NSITEISDNEDDLL----EYHRRQRQER-------LREQEMERLERQRLETILNL 620
RE+K E+ E+ LL E RRQ ER L+++E + L +R + L
Sbjct: 986 REKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQE 1045
Query: 621 CAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESME 680
R + + E +GE R + L + E Q L E E
Sbjct: 1046 RERQYREEEELQQEEEQLLGEERET------RRRQELERQYRKEEELQQEEEQLLREEPE 1099
Query: 681 RSDEENLKEECSSTESTQQEHE----DAPSTKLQGEVLALEEERAQVLGHVEQL------ 730
+ + + +C E QQE E + + + E+ E +V EQL
Sbjct: 1100 KRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPE 1159
Query: 731 KVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKL---------- 780
K R +ELE+Q +E + E LL+ E+E R +++ + ++LQ +
Sbjct: 1160 KRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQ 1219
Query: 781 ---VALETGIQKE---RDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSK 834
+ + +KE RD + E + F LE QL ++ + L G+ R +
Sbjct: 1220 RSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDR 1279
Query: 835 AELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRY 894
+ R +R + Q+ + +E++R R QLL++E+E E+R
Sbjct: 1280 EQERRRWQQRDRHF----PEEEQLEREEQKEAKRRDRKSQEEKQLLREERE-----EKRR 1330
Query: 895 HSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQE 929
T R F + L+E E+ L + ++ ++E
Sbjct: 1331 RQET-DRKFREEEQLLQEREEQPLRRQERDRKFRE 1364
Score = 56.6 bits (135), Expect = 2e-07
Identities = 88/392 (22%), Positives = 157/392 (40%), Gaps = 49/392 (12%)
Query: 574 ERKNSITEISDNEDDLLEYHRRQRQER-----LREQEMERLERQRLETILNLCAEYSRAD 628
ER+ + + + E+ + RR++QER RE+E ERLE++ E A+
Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687
Query: 629 GGPEAG-------------ELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRL 675
E +L S +A + + R G + + ++
Sbjct: 688 EEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQ 747
Query: 676 WESMERSDEENLKEEC-----------SSTESTQQEHEDAPSTKLQGEVLALEEERAQVL 724
W+ ER+ + +EE +E +Q P + Q E EER Q
Sbjct: 748 WQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQ-- 805
Query: 725 GHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAE-RALLQKEQKAVDQLQEKLVAL 783
EQ + +E ++Q + RE E E L+ E + + R Q+ Q+ D LQE
Sbjct: 806 --REQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERR 863
Query: 784 ETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAK 843
+ Q+ K LE E K + + + ++ +E++L L + EL R +
Sbjct: 864 RSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQL----LQEEEEELQREERE 919
Query: 844 RKERLAILDSQAGQIR--AQAVQESERLARDKNASLQLLQKEKE--KLTVLERRYHSLTG 899
++ R Q Q R Q QE E+L R++ + ++E++ K L+++ L G
Sbjct: 920 KRRR----QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLG 975
Query: 900 GRPFPKTTSTLKEMEKLLLPAVDLEQWYQELM 931
P + +E EK +L+Q ++L+
Sbjct: 976 EEPEKRRR---QEREKKYREEEELQQEEEQLL 1004
Score = 50.8 bits (120), Expect = 9e-06
Identities = 60/261 (22%), Positives = 115/261 (44%), Gaps = 18/261 (6%)
Query: 666 EEPGVATQRLWESMER--SDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQ- 722
EEPG ++ + ER ++ E E+ E ++ D + + E EE RA+
Sbjct: 131 EEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEE 190
Query: 723 -----VLGH-VEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQL 776
GH E+ + ++L E R+ E+ + ER+ +R ++E+K +
Sbjct: 191 EQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQQRRERQ-DRVFQEEEEKEWRKR 249
Query: 777 QEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAE 836
+ L E +Q+E + L+ E + LE Q+L RE + EE+++ Q L R +
Sbjct: 250 ETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQ---QRLRREQQL 306
Query: 837 LLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASL-QLLQKEKEKLTVLERRYH 895
+ +R+E+ Q + Q + ++L R++ Q L++E+E+ ERR
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEE----ERREQ 362
Query: 896 SLTGGRPFPKTTSTLKEMEKL 916
L + + L+ ++L
Sbjct: 363 QLRREQEEERREQQLRREQQL 383
Score = 50.8 bits (120), Expect = 9e-06
Identities = 88/384 (22%), Positives = 169/384 (44%), Gaps = 42/384 (10%)
Query: 559 QRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERL--REQEMERLERQRLET 616
+RK + ++ R RK E E + + HR++R + EQ++ R ER R
Sbjct: 1445 ERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFR 1504
Query: 617 ILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLW 676
L ++ E +L +R + L +E G Q+
Sbjct: 1505 EQELRSQEPERKFLEEEQQLHR-----------QQRQRKFLQEEQQLRRQERG---QQRR 1550
Query: 677 ESMERS--DEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRV 734
+ +R +EE L++E + ++QE + +L+ + + +E+ + + +QL R
Sbjct: 1551 QDRDRKFREEEQLRQEREEQQLSRQERDR--KFRLEEQKVRRQEQERKFMEDEQQL--RR 1606
Query: 735 KELEQQL-QESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDK 793
+E +QQL QE R+ + LLQ ERE ++ Q+ + + + +L E Q D+
Sbjct: 1607 QEGQQQLRQERDRKFREDEQLLQ-EREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDR 1665
Query: 794 EAEALETETKLFEDLEFQQLERESR----VEEERELAGQ----GLLRSKAELLRSIAKRK 845
+ + E E +L ++ E QQL R+ R EEE++L Q L+ + +L R +RK
Sbjct: 1666 DRKFRE-EEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERK 1724
Query: 846 ERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPK 905
R + Q+R + QE R + ++L++E+ + E++ R F +
Sbjct: 1725 FR------EEEQLRQETEQEQ---LRRQERYRKILEEEQLRPEREEQQLRRQERDRKFRE 1775
Query: 906 TTSTLKEMEKLLLPAVDLEQWYQE 929
+E E+ L + + ++ ++E
Sbjct: 1776 EEQLRQEREEQQLRSQESDRKFRE 1799
Score = 50.1 bits (118), Expect = 1e-05
Identities = 63/249 (25%), Positives = 112/249 (44%), Gaps = 38/249 (15%)
Query: 681 RSDEENLKEECSSTESTQQEHE--DAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELE 738
R +E+ ++ + + ++E + K + E L+E Q L H ++ + E E
Sbjct: 1433 REEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQL-HRQERDRKFLEEE 1491
Query: 739 QQL----------QESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQ 788
QQL ++ R E ER L+ E++ R Q+ Q+ Q +++L E G Q
Sbjct: 1492 QQLRRQERDRKFREQELRSQEPERKFLEEEQQLHR---QQRQRKFLQEEQQLRRQERGQQ 1548
Query: 789 KERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERL 848
+ +D++ + E E +L ++ E QQL R+ R + + L Q + R + +ER
Sbjct: 1549 RRQDRDRKFRE-EEQLRQEREEQQLSRQER-DRKFRLEEQKVRR----------QEQERK 1596
Query: 849 AILDSQAGQIRAQAVQESERLARDK--NASLQLLQKEKEKLTVLERRYHSLTGGRPFPKT 906
+ D Q Q+R Q Q+ R RD+ QLLQ+ + E++ H R F +
Sbjct: 1597 FMEDEQ--QLRRQEGQQQLRQERDRKFREDEQLLQERE------EQQLHRQERDRKFLEE 1648
Query: 907 TSTLKEMEK 915
L+ E+
Sbjct: 1649 EPQLRRQER 1657
Score = 49.7 bits (117), Expect = 2e-05
Identities = 81/318 (25%), Positives = 132/318 (41%), Gaps = 32/318 (10%)
Query: 559 QRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETIL 618
Q + G ++ R+RK E E + + HR++R + E+E +L RQ E L
Sbjct: 1603 QLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEE-PQLRRQEREQQL 1661
Query: 619 NLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGV---ATQRL 675
+ R E +L GE R R R E Q
Sbjct: 1662 ----RHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLR 1717
Query: 676 WESMERS--DEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVR 733
+ +ER +EE L++E TE Q ++ L+ E L E E Q+ K R
Sbjct: 1718 RQELERKFREEEQLRQE---TEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFR 1774
Query: 734 VKEL------EQQL--QESAREAEMERALLQGEREAERALLQKEQK-AVDQLQEKLVALE 784
+E EQQL QES R+ E L Q E + Q++ K ++ Q +L E
Sbjct: 1775 EEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQE 1834
Query: 785 TGIQKERDK-----EAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLR 839
+++ERD+ E A + +++ E +Q+ E++ R E ER+L + + R + E
Sbjct: 1835 QRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKE--- 1891
Query: 840 SIAKRKERLAILDSQAGQ 857
+R ++ + SQ G+
Sbjct: 1892 --EQRHRQVGEIKSQEGK 1907
Score = 48.9 bits (115), Expect = 3e-05
Identities = 32/84 (38%), Positives = 46/84 (54%), Gaps = 2/84 (2%)
Query: 1150 EMEKMLKEAHAEKNRLMESREREMELRRQALE-EERRRREQVERRLQSESARRQQL-VEK 1207
+ E+ +E E+ E RE++ E R Q L E+ RREQ RR Q E R QQL E+
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
Query: 1208 EVKMREKQFSQARPLTRYLPIRKE 1231
E + RE+Q + + L R +R+E
Sbjct: 369 EEERREQQLRREQQLRREQQLRRE 392
Score = 48.5 bits (114), Expect = 4e-05
Identities = 53/207 (25%), Positives = 86/207 (41%), Gaps = 31/207 (14%)
Query: 1030 ETKRQLALQQKGQQVIEE----QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPP 1085
++++Q L+Q+ +Q +E QR+ E +++ A E Q Q H FP
Sbjct: 154 QSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQ---- 209
Query: 1086 LMHHSILHHLPAGRE-----RGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSA 1140
L +L GRE R E + + + ET + + +
Sbjct: 210 LRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRK------EEEKLQEE 263
Query: 1141 SGLDMGKIEEMEKMLKEAHAEKNRLMESRE--------REMELRRQALEEERR----RRE 1188
+++E E+ L++ ++ R E RE +LRR+ EE R RRE
Sbjct: 264 EPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE 323
Query: 1189 QVERRLQSESARRQQLVEKEVKMREKQ 1215
Q ERR Q E R QQL ++ + RE+Q
Sbjct: 324 QQERREQQEERREQQLRREQEERREQQ 350
Score = 48.1 bits (113), Expect = 6e-05
Identities = 29/83 (34%), Positives = 44/83 (53%), Gaps = 3/83 (3%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKE 1208
+E + +E ++ R + RE +LRR E+E RREQ RR Q E R QQL ++
Sbjct: 325 QERREQQEERREQQLRREQEERREQQLRR---EQEEERREQQLRREQEEERREQQLRREQ 381
Query: 1209 VKMREKQFSQARPLTRYLPIRKE 1231
RE+Q + + L R +R+E
Sbjct: 382 QLRREQQLRREQQLRREQQLRRE 404
Score = 45.8 bits (107), Expect = 3e-04
Identities = 30/105 (28%), Positives = 56/105 (53%), Gaps = 15/105 (14%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMES----REREMELRRQ------ALEEERRRREQVERRLQS 1196
K E E++L+E ++ R E RE E +LRRQ EE++ RR+++ER+ +
Sbjct: 1668 KFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFRE 1727
Query: 1197 ESARRQQLVEKEVKMREK-----QFSQARPLTRYLPIRKEDFDLK 1236
E RQ+ +++++ +E+ + Q RP +R+++ D K
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRK 1772
Score = 44.7 bits (104), Expect = 6e-04
Identities = 31/85 (36%), Positives = 44/85 (51%), Gaps = 3/85 (3%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQAL--EEERRRREQVERRLQSESARRQQLVE 1206
E E+ L+ E+ RE+E E R Q L E+E RREQ RR Q + R QQL
Sbjct: 333 ERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQ-QLRREQQLRR 391
Query: 1207 KEVKMREKQFSQARPLTRYLPIRKE 1231
++ RE+Q + + L R +R+E
Sbjct: 392 EQQLRREQQLRREQQLRREQQLRRE 416
Score = 44.7 bits (104), Expect = 6e-04
Identities = 86/401 (21%), Positives = 155/401 (38%), Gaps = 66/401 (16%)
Query: 566 DLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERL-ERQRLETILNLCAEY 624
DL+ E++N++ DN+ Y + + E+ R+ E +L +RQ + + +L E
Sbjct: 1222 DLKWQWEPEKENAVR---DNK----VYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQ 1274
Query: 625 SRADGGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSD- 683
D E R + +S EE + + E R +
Sbjct: 1275 QERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQET 1334
Query: 684 EENLKEECSSTESTQQEHEDAP------STKLQGEVLALEEERAQVLGHVEQLK------ 731
+ +EE E QE E+ P K + E L +E+ + L ++L+
Sbjct: 1335 DRKFREE----EQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERER 1390
Query: 732 --------VRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQE-KLVA 782
+R +E EQQL++ E +E +R ++EQ+ Q +E K +
Sbjct: 1391 KFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLE 1450
Query: 783 LETGIQKERDKEAEALETETKLFEDLEFQQL---ERESRV-EEERELAGQ---------- 828
E +++ER ++ E +L ++ E QQL ER+ + EEE++L Q
Sbjct: 1451 EEQQLRQERHRK---FREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE 1507
Query: 829 --------GLLRSKAELLRSIAKRK---ERLAILDSQAGQIRAQ----AVQESERLARDK 873
L + +L R +RK E + + GQ R Q +E E+L +++
Sbjct: 1508 LRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQER 1567
Query: 874 NASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEME 914
Q+ K + E++ R F + L+ E
Sbjct: 1568 EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQE 1608
Score = 43.5 bits (101), Expect = 0.001
Identities = 26/84 (30%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query: 1149 EEMEKMLKEAHAEKNRLME-SREREMELRRQALEEERRRREQVERRLQSESARRQQLVEK 1207
E E+ L+ E+ R + RE+E E R Q L E++ R + + R + + R QQL +
Sbjct: 345 ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRRE 404
Query: 1208 EVKMREKQFSQARPLTRYLPIRKE 1231
+ RE+Q + + L R +R+E
Sbjct: 405 QQLRREQQLRREQQLRREQQLRRE 428
Score = 43.5 bits (101), Expect = 0.001
Identities = 62/275 (22%), Positives = 108/275 (39%), Gaps = 18/275 (6%)
Query: 554 QSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQR 613
+ P ++R+ LR R+ + + + E+ L R R+ R EQ++ R ER+R
Sbjct: 1648 EEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERER 1707
Query: 614 LETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQ 673
L + R + + E + + T L + R + E +
Sbjct: 1708 --KFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLR 1765
Query: 674 RLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVR 733
R + +EE L++E E Q +++ + E L E E Q+ K R
Sbjct: 1766 RQERDRKFREEEQLRQE---REEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYR 1822
Query: 734 VKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDK 793
+E + QL+E + ER +R +EQ A QEK E + +E ++
Sbjct: 1823 WEEEQLQLEEQEQRLRQER---------DRQYRAEEQFAT---QEKSRREEQELWQEEEQ 1870
Query: 794 EAEALETETKLFEDLEFQQLERESRVEEERELAGQ 828
+ E E KL E+ +Q + E R + E+ Q
Sbjct: 1871 KRRQ-ERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904
Score = 41.2 bits (95), Expect = 0.007
Identities = 24/75 (32%), Positives = 36/75 (48%), Gaps = 2/75 (2%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQAL--EEERRRREQVERRLQSESARRQQLVE 1206
E +++LK E+ R + R + E R Q L EEE R EQ +R E R Q+L E
Sbjct: 628 ERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAE 687
Query: 1207 KEVKMREKQFSQARP 1221
+E + ++ P
Sbjct: 688 EEQEQARERIKSRIP 702
Score = 40.8 bits (94), Expect = 0.009
Identities = 63/308 (20%), Positives = 128/308 (41%), Gaps = 20/308 (6%)
Query: 584 DNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEAT 643
+ E+ L R R+ RL EQ++ R E++R + + R +G + +
Sbjct: 1566 EREEQQLSRQERDRKFRLEEQKVRRQEQER--KFMEDEQQLRRQEGQQQLRQERDRKFRE 1623
Query: 644 AALALAGRRPSRGLAGASGRS--SEEPGVATQRLWESMERSDEENLKEECSSTES--TQQ 699
L R + R EEP + Q + + + +EE + QQ
Sbjct: 1624 DEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQ 1683
Query: 700 EHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAR-EAEMERALLQGE 758
K + E L + + E+ ++R +ELE++ +E + E E+ L+
Sbjct: 1684 LRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLR-R 1742
Query: 759 REAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESR 818
+E R +L++EQ ++ +++L ++ERD++ E +L ++ E QQL +
Sbjct: 1743 QERYRKILEEEQLRPEREEQQL------RRQERDRK---FREEEQLRQEREEQQLRSQ-- 1791
Query: 819 VEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQ 878
E +R+ + LR + E + ++++ + + Q+ Q + + R A Q
Sbjct: 1792 -ESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQ 1850
Query: 879 LLQKEKEK 886
+EK +
Sbjct: 1851 FATQEKSR 1858
Score = 39.7 bits (91), Expect = 0.020
Identities = 28/91 (30%), Positives = 52/91 (57%), Gaps = 7/91 (7%)
Query: 1149 EEMEKMLK-EAHAEKNRLMESREREME--LRRQALE--EERRRREQVERRLQSESARRQQ 1203
E +++LK E + RL +E +E L+R+ +E E+ RREQ +R + E RRQQ
Sbjct: 573 ERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQ 632
Query: 1204 LV--EKEVKMREKQFSQARPLTRYLPIRKED 1232
L+ E++ + R++Q + + R +++E+
Sbjct: 633 LLKSEEQEERRQQQLRREQQERREQRLKREE 663
Score = 38.1 bits (87), Expect = 0.059
Identities = 27/90 (30%), Positives = 44/90 (48%), Gaps = 8/90 (8%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMESREREMELRRQALE----EERRRREQVERRLQSESARRQ 1202
K E E+ L+ E+ L E E +LRRQ LE EE + R++ E+ R +
Sbjct: 1692 KFREEEQQLRRQERERKFLQE----EQQLRRQELERKFREEEQLRQETEQEQLRRQERYR 1747
Query: 1203 QLVEKEVKMREKQFSQARPLTRYLPIRKED 1232
+++E+E E++ Q R R R+E+
Sbjct: 1748 KILEEEQLRPEREEQQLRRQERDRKFREEE 1777
Score = 37.7 bits (86), Expect = 0.077
Identities = 42/194 (21%), Positives = 85/194 (43%), Gaps = 22/194 (11%)
Query: 722 QVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLV 781
Q G E+ + R E LQ+ +E + R + + E ++ QK +Q +E
Sbjct: 91 QATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAE 150
Query: 782 ALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEER----------------EL 825
E ++ER ++ + + +L+ + Q E R EEE+ +L
Sbjct: 151 GEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQL 210
Query: 826 AGQGLL----RSKAELLRSIAKRKERLAILDSQAGQIRAQAV--QESERLARDKNASLQL 879
+ LL + + E + +R++R+ + + + + V +E E+L ++ +
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRE 270
Query: 880 LQKEKEKLTVLERR 893
LQ+E+E+L LER+
Sbjct: 271 LQEEEEQLRKLERQ 284
Score = 37.7 bits (86), Expect = 0.077
Identities = 28/97 (28%), Positives = 50/97 (51%), Gaps = 10/97 (10%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKE 1208
EE + L+E ++ RL + R+R+ Q +E+ RRE+ E + E RRQ E+E
Sbjct: 1824 EEEQLQLEE---QEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQ---ERE 1877
Query: 1209 VKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHG 1245
K+RE+ + + + ++ ++K+ E GHG
Sbjct: 1878 RKLREEHIRRQQKEEQR---HRQVGEIKSQ-EGKGHG 1910
Score = 37.4 bits (85), Expect = 0.10
Identities = 27/88 (30%), Positives = 49/88 (55%), Gaps = 2/88 (2%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKE 1208
E K+L+E R E + R E R+ EEE+ R+E+ E++L+S+ + R+ E++
Sbjct: 1744 ERYRKILEEEQLRPER-EEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQ 1802
Query: 1209 VKMREKQFSQARPLTRYLPIRKEDFDLK 1236
++ +E++ Q RP R R E+ L+
Sbjct: 1803 LR-QEREEQQLRPQQRDGKYRWEEEQLQ 1829
Score = 37.0 bits (84), Expect = 0.13
Identities = 37/132 (28%), Positives = 56/132 (42%), Gaps = 11/132 (8%)
Query: 1100 ERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLK--- 1156
ER E+ E L E + E + + S L + E E++LK
Sbjct: 495 ERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREE 554
Query: 1157 EAHAEKNRLMESREREMELRRQAL---EEERR----RREQVERRLQSESARRQQLVEKEV 1209
E E+ R + +RE E RR L EEERR +REQ E RL+ R + ++
Sbjct: 555 EKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQ-EERLEQRLKREEVERLEQE 613
Query: 1210 KMREKQFSQARP 1221
+ RE++ + P
Sbjct: 614 ERREQRLKREEP 625
Score = 37.0 bits (84), Expect = 0.13
Identities = 24/88 (27%), Positives = 49/88 (55%), Gaps = 4/88 (4%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQALEE--ERRRREQVERRLQSESARRQQLVE 1206
EE E++ + +E+ E ER +L ++ E+ E+ RREQ +R Q E RR QL++
Sbjct: 523 EEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE--RRDQLLK 580
Query: 1207 KEVKMREKQFSQARPLTRYLPIRKEDFD 1234
+E + R+++ + + +++E+ +
Sbjct: 581 REEERRQQRLKREQEERLEQRLKREEVE 608
Score = 37.0 bits (84), Expect = 0.13
Identities = 24/86 (27%), Positives = 43/86 (50%), Gaps = 1/86 (1%)
Query: 1148 IEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEK 1207
++E E+ L+ EK R E + E + EEE+ RE+ E+R + E RQ +K
Sbjct: 906 LQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQE-RERQYRKDK 964
Query: 1208 EVKMREKQFSQARPLTRYLPIRKEDF 1233
+++ +E+Q P R R++ +
Sbjct: 965 KLQQKEEQLLGEEPEKRRRQEREKKY 990
Score = 36.6 bits (83), Expect = 0.17
Identities = 20/77 (25%), Positives = 37/77 (48%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKE 1208
E E+ L+ E+ R + R + R Q L E++ R + + R + + R QQL ++
Sbjct: 358 ERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQ 417
Query: 1209 VKMREKQFSQARPLTRY 1225
RE+Q + + R+
Sbjct: 418 QLRREQQLRREQEEERH 434
Score = 36.6 bits (83), Expect = 0.17
Identities = 28/80 (35%), Positives = 45/80 (56%), Gaps = 16/80 (20%)
Query: 1147 KIEEMEKMLKEAHAEKNRLME-------SREREMELRRQALEEERRRREQVERRLQSESA 1199
++EE E+ L++ + R E SR E EL ++ EE++RR+E+ ER+L+ E
Sbjct: 1829 QLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQE--EEQKRRQER-ERKLREEHI 1885
Query: 1200 RRQQLVEK------EVKMRE 1213
RRQQ E+ E+K +E
Sbjct: 1886 RRQQKEEQRHRQVGEIKSQE 1905
Score = 36.2 bits (82), Expect = 0.22
Identities = 31/104 (29%), Positives = 48/104 (46%), Gaps = 19/104 (18%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMESRER-EMELRRQALEE---------ERRRREQVERRLQ- 1195
K+EE E+ ++ E+ E ER E L+RQ EE ++ RREQ ERR Q
Sbjct: 490 KLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQL 549
Query: 1196 --------SESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKE 1231
E RR+Q +++E + R Q + R +++E
Sbjct: 550 LKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
Score = 35.8 bits (81), Expect = 0.29
Identities = 31/89 (34%), Positives = 42/89 (47%), Gaps = 7/89 (7%)
Query: 1150 EMEKMLKEAHAEKNRLMESREREMELRRQAL--EEERRRREQVER-----RLQSESARRQ 1202
E E+ E E+ R + +RE E RR L EEE R EQ R R Q E R +
Sbjct: 428 EQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRER 487
Query: 1203 QLVEKEVKMREKQFSQARPLTRYLPIRKE 1231
L +E + RE+Q + + L R R+E
Sbjct: 488 WLKLEEEERREQQERREQQLRREQEERRE 516
Score = 35.4 bits (80), Expect = 0.38
Identities = 24/77 (31%), Positives = 42/77 (54%), Gaps = 2/77 (2%)
Query: 1157 EAHAEKNRLME-SREREMELRRQALE-EERRRREQVERRLQSESARRQQLVEKEVKMREK 1214
E H ++ R + R++E E R + L+ EE RREQ ERR Q +++ E+ +K +E+
Sbjct: 465 ERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEE 524
Query: 1215 QFSQARPLTRYLPIRKE 1231
+ + L +R+E
Sbjct: 525 EERLQQRLRSEQQLRRE 541
Score = 35.4 bits (80), Expect = 0.38
Identities = 28/90 (31%), Positives = 50/90 (55%), Gaps = 14/90 (15%)
Query: 1149 EEMEKMLKEAHAEKNRL-MESREREMELRRQALEE------ERRRREQVERRLQSESARR 1201
+E E++L+E ++ R +E + RE E +Q E+ E+RRR+++ER+ + E +
Sbjct: 1118 QEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQ 1177
Query: 1202 Q---QLV----EKEVKMREKQFSQARPLTR 1224
Q QL+ EK + RE+Q+ + L R
Sbjct: 1178 QEEEQLLREEQEKRRQERERQYREEEELQR 1207
Score = 35.0 bits (79), Expect = 0.50
Identities = 18/65 (27%), Positives = 36/65 (55%), Gaps = 1/65 (1%)
Query: 1150 EMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEV 1209
E E++ +E E R + E +L R+ EE+RRR++ +R+ + E Q+ E+ +
Sbjct: 1295 EEEQLEREEQKEAKRRDRKSQEEKQLLREE-REEKRRRQETDRKFREEEQLLQEREEQPL 1353
Query: 1210 KMREK 1214
+ +E+
Sbjct: 1354 RRQER 1358
Score = 35.0 bits (79), Expect = 0.50
Identities = 22/84 (26%), Positives = 44/84 (52%), Gaps = 1/84 (1%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKE 1208
+E+E+ +E + + + R E R+ LEEE+ R E+ E++L+ + R ++ E+E
Sbjct: 1719 QELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQE-RDRKFREEE 1777
Query: 1209 VKMREKQFSQARPLTRYLPIRKED 1232
+E++ Q R R+E+
Sbjct: 1778 QLRQEREEQQLRSQESDRKFREEE 1801
Score = 34.7 bits (78), Expect = 0.65
Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 1/97 (1%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKE 1208
E E+ L+ + RE+++ +Q E++ RREQ RR Q +Q E+E
Sbjct: 371 ERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQE 430
Query: 1209 VKMREKQFSQARPLTRYLPIRKEDFD-LKTHIESSGH 1244
+ E++ Q R R ++E D LK E+ H
Sbjct: 431 EERHEQKHEQERREQRLKREQEERRDWLKREEETERH 467
Score = 34.7 bits (78), Expect = 0.65
Identities = 28/86 (32%), Positives = 40/86 (46%), Gaps = 14/86 (16%)
Query: 1149 EEMEKMLKEAHAEKNR-----LMESREREMELRRQALEEERRRREQVERR-----LQSES 1198
E ++ LK E+ R L E RE + RR E++ RREQ ERR Q E
Sbjct: 470 ERRKQQLKRDQEEERRERWLKLEEEERREQQERR----EQQLRREQEERREQRLKRQEEE 525
Query: 1199 ARRQQLVEKEVKMREKQFSQARPLTR 1224
R QQ + E ++R +Q + L +
Sbjct: 526 ERLQQRLRSEQQLRREQEERREQLLK 551
Score = 34.7 bits (78), Expect = 0.65
Identities = 21/93 (22%), Positives = 45/93 (48%), Gaps = 3/93 (3%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMES---REREMELRRQALEEERRRREQVERRLQSESARRQQ 1203
++E + +E E+ +L+ + R E RQ EEE ++E+ + + RR+Q
Sbjct: 1075 ELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQ 1134
Query: 1204 LVEKEVKMREKQFSQARPLTRYLPIRKEDFDLK 1236
+E++ + E+ + L R P ++ +L+
Sbjct: 1135 ELERQYREEEEVQQEEEQLLREEPEKRRRQELE 1167
Score = 34.3 bits (77), Expect = 0.85
Identities = 24/87 (27%), Positives = 41/87 (47%), Gaps = 1/87 (1%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVE 1206
K+++ E+ L EK R E ++ E EEE+ RE+ E+R + E RQ +
Sbjct: 965 KLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQE-WERQYRKK 1023
Query: 1207 KEVKMREKQFSQARPLTRYLPIRKEDF 1233
E++ E+Q + R L R+ +
Sbjct: 1024 DELQQEEEQLLREEREKRRLQERERQY 1050
Score = 34.3 bits (77), Expect = 0.85
Identities = 24/82 (29%), Positives = 40/82 (48%), Gaps = 6/82 (7%)
Query: 1149 EEMEKMLKEAHA----EKNRLMESRE--REMELRRQALEEERRRREQVERRLQSESARRQ 1202
+E E+ +E E+ L E RE R EL RQ EEE ++E+ + + RR+
Sbjct: 1104 QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRR 1163
Query: 1203 QLVEKEVKMREKQFSQARPLTR 1224
Q +E++ + E+ + L R
Sbjct: 1164 QELERQYREEEELQQEEEQLLR 1185
Score = 34.3 bits (77), Expect = 0.85
Identities = 24/86 (27%), Positives = 44/86 (51%), Gaps = 7/86 (8%)
Query: 1148 IEEMEKMLKEAHA---EKNRLMESREREM----ELRRQALEEERRRREQVERRLQSESAR 1200
+EE +++ +E H E+ +L++ RE + E R+ LEEE++ R Q R E
Sbjct: 1449 LEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQEL 1508
Query: 1201 RQQLVEKEVKMREKQFSQARPLTRYL 1226
R Q E++ E+Q + + ++L
Sbjct: 1509 RSQEPERKFLEEEQQLHRQQRQRKFL 1534
Score = 34.3 bits (77), Expect = 0.85
Identities = 19/67 (28%), Positives = 42/67 (62%), Gaps = 1/67 (1%)
Query: 1150 EMEKMLKEAHAEKNRLMESREREMELRRQALEEERR-RREQVERRLQSESARRQQLVEKE 1208
E +++ ++ K RL E + R E R+ +E+E++ RR++ +++L+ E R+ + E+
Sbjct: 1568 EEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQL 1627
Query: 1209 VKMREKQ 1215
++ RE+Q
Sbjct: 1628 LQEREEQ 1634
Score = 34.3 bits (77), Expect = 0.85
Identities = 20/70 (28%), Positives = 40/70 (57%), Gaps = 2/70 (2%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMES--REREMELRRQALEEERRRREQVERRLQSESARRQQL 1204
KI E E++ E ++ R E + RE E RQ EE++ R ++ +R+ + E RQ+
Sbjct: 1748 KILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQER 1807
Query: 1205 VEKEVKMREK 1214
E++++ +++
Sbjct: 1808 EEQQLRPQQR 1817
Score = 33.9 bits (76), Expect = 1.1
Identities = 21/67 (31%), Positives = 36/67 (53%), Gaps = 2/67 (2%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKE 1208
+E E++L+E ++ R R+ + Q EE+ R E+ +RRLQ RQ E+E
Sbjct: 998 QEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERE--RQYREEEE 1055
Query: 1209 VKMREKQ 1215
++ E+Q
Sbjct: 1056 LQQEEEQ 1062
Score = 33.9 bits (76), Expect = 1.1
Identities = 22/77 (28%), Positives = 41/77 (53%), Gaps = 4/77 (5%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMES---REREMELRRQALEEERRRREQVERRLQSESARRQQ 1203
++E + +E E+ +L+ + R EL RQ EEE ++E+ E+ L+ E +R+Q
Sbjct: 1135 ELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEE-EQLLREEQEKRRQ 1193
Query: 1204 LVEKEVKMREKQFSQAR 1220
E++ + E+ Q R
Sbjct: 1194 ERERQYREEEELQRQKR 1210
Score = 33.9 bits (76), Expect = 1.1
Identities = 19/78 (24%), Positives = 40/78 (51%), Gaps = 3/78 (3%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKE 1208
E+ E ++ +++ + + ERE + RRQ + + R EQ+ + + + RRQ E++
Sbjct: 1303 EQKEAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQ---ERD 1359
Query: 1209 VKMREKQFSQARPLTRYL 1226
K RE++ ++L
Sbjct: 1360 RKFREEELRHQEQGRKFL 1377
Score = 33.9 bits (76), Expect = 1.1
Identities = 26/86 (30%), Positives = 41/86 (47%), Gaps = 17/86 (19%)
Query: 1147 KIEEMEKMLKEAHAEKNR-------------LMESRE----REMELRRQALEEERRRREQ 1189
K +E +++L+E EK R L++ RE R E R+ EEE R +EQ
Sbjct: 1313 KSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQ 1372
Query: 1190 VERRLQSESARRQQLVEKEVKMREKQ 1215
+ L+ E R+Q E++ E+Q
Sbjct: 1373 GRKFLEEEQRLRRQERERKFLKEEQQ 1398
Score = 33.9 bits (76), Expect = 1.1
Identities = 21/76 (27%), Positives = 41/76 (53%), Gaps = 4/76 (5%)
Query: 1156 KEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKMREKQ 1215
+E ++R + RE E +L RQ + + R EQ RR + R ++ +E+E ++R+++
Sbjct: 1404 REQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQE----RERKFLEEEQQLRQER 1459
Query: 1216 FSQARPLTRYLPIRKE 1231
+ R + L R+E
Sbjct: 1460 HRKFREEEQLLQEREE 1475
Score = 33.9 bits (76), Expect = 1.1
Identities = 26/104 (25%), Positives = 53/104 (50%), Gaps = 7/104 (6%)
Query: 1148 IEEMEKMLKEAHAEKNRLMESRE-REMELRRQALEEERRRREQVER--RLQSESARRQQ- 1203
++E +++ ++ ++ R R+ RE E RQ EE++ R++ +R RL+ + RRQ+
Sbjct: 1534 LQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQ 1593
Query: 1204 ---LVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGH 1244
+E E ++R ++ Q R R+++ L+ E H
Sbjct: 1594 ERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLH 1637
Score = 33.5 bits (75), Expect = 1.4
Identities = 17/68 (25%), Positives = 36/68 (52%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVE 1206
++ + +++L+E E R + R E RQ EEE+ ++E+ + + RR+Q E
Sbjct: 898 QLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERE 957
Query: 1207 KEVKMREK 1214
++ + +K
Sbjct: 958 RQYRKDKK 965
Score = 33.5 bits (75), Expect = 1.4
Identities = 21/77 (27%), Positives = 41/77 (53%), Gaps = 10/77 (12%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQALEE-------ERRRREQVERRLQSESARR 1201
+E E++L+E ++ R R+ + + Q EE E+RRR++ E++ + E +
Sbjct: 938 QEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQ 997
Query: 1202 Q---QLVEKEVKMREKQ 1215
Q QL+ +E + R +Q
Sbjct: 998 QEEEQLLREEREKRRRQ 1014
Score = 33.5 bits (75), Expect = 1.4
Identities = 27/93 (29%), Positives = 46/93 (49%), Gaps = 7/93 (7%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMES--REREMELRRQA-----LEEERRRREQVERRLQSESA 1199
K E E++L+E + R E + RE ELR Q LEEE+R R Q R +
Sbjct: 1337 KFREEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEE 1396
Query: 1200 RRQQLVEKEVKMREKQFSQARPLTRYLPIRKED 1232
++ + E+E ++R+ + + R + L ++ D
Sbjct: 1397 QQLRCQEREQQLRQDRDRKFREEEQQLSRQERD 1429
Score = 33.1 bits (74), Expect = 1.9
Identities = 25/82 (30%), Positives = 44/82 (53%), Gaps = 8/82 (9%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKE 1208
+E E++L+E EK RL +ERE RQ EEE ++E+ + + RR+Q +E++
Sbjct: 1028 QEEEQLLREER-EKRRL---QERE----RQYREEEELQQEEEQLLGEERETRRRQELERQ 1079
Query: 1209 VKMREKQFSQARPLTRYLPIRK 1230
+ E+ + L R P ++
Sbjct: 1080 YRKEEELQQEEEQLLREEPEKR 1101
Score = 33.1 bits (74), Expect = 1.9
Identities = 22/74 (29%), Positives = 36/74 (48%), Gaps = 3/74 (4%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVE 1206
++++ E+ L EK R E + E EEE+ RE+ E+R Q R +Q E
Sbjct: 1145 EVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE---RERQYRE 1201
Query: 1207 KEVKMREKQFSQAR 1220
+E R+K+ + R
Sbjct: 1202 EEELQRQKRKQRYR 1215
Score = 32.7 bits (73), Expect = 2.5
Identities = 27/101 (26%), Positives = 43/101 (42%), Gaps = 10/101 (9%)
Query: 1152 EKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKM 1211
+++ +E E+ RE E E R Q L EE + EQ R++S + Q +E E
Sbjct: 657 QRLKREEEEERLEQRLKREHEEERREQELAEEEQ--EQARERIKSRIPKWQWQLESEADA 714
Query: 1212 RE--------KQFSQARPLTRYLPIRKEDFDLKTHIESSGH 1244
R+ KQ Q R + R+ + +L+ E H
Sbjct: 715 RQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAH 755
Score = 32.7 bits (73), Expect = 2.5
Identities = 25/84 (29%), Positives = 43/84 (51%), Gaps = 13/84 (15%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQALEEER--RRREQVERRL--------QSES 1198
EE EK ++ +K R E ++E E Q L EER RRR++ ER+ + E
Sbjct: 976 EEPEKRRRQEREKKYREEEELQQEEE---QLLREEREKRRRQEWERQYRKKDELQQEEEQ 1032
Query: 1199 ARRQQLVEKEVKMREKQFSQARPL 1222
R++ ++ ++ RE+Q+ + L
Sbjct: 1033 LLREEREKRRLQERERQYREEEEL 1056
Score = 32.3 bits (72), Expect = 3.2
Identities = 23/84 (27%), Positives = 41/84 (48%), Gaps = 6/84 (7%)
Query: 1147 KIEEMEKMLKEAHA----EKNRLMESRE--REMELRRQALEEERRRREQVERRLQSESAR 1200
+++E E+ +E E+ L E RE R EL RQ +EE ++E+ + + R
Sbjct: 1042 RLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKR 1101
Query: 1201 RQQLVEKEVKMREKQFSQARPLTR 1224
R+Q E++ + E+ + L R
Sbjct: 1102 RRQERERQCREEEELQQEEEQLLR 1125
Score = 32.3 bits (72), Expect = 3.2
Identities = 19/69 (27%), Positives = 37/69 (53%), Gaps = 5/69 (7%)
Query: 1149 EEMEKMLKEAHAEKNRLMESR---EREMELRRQALEEERRRREQVERRLQSESARRQQLV 1205
+E E+ E + +R R + E +LRRQ E ++RR+ +R+ + E RQ+
Sbjct: 1511 QEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQ--ERGQQRRQDRDRKFREEEQLRQERE 1568
Query: 1206 EKEVKMREK 1214
E+++ +E+
Sbjct: 1569 EQQLSRQER 1577
Score = 32.0 bits (71), Expect = 4.2
Identities = 18/71 (25%), Positives = 35/71 (49%), Gaps = 4/71 (5%)
Query: 1149 EEMEKMLKEAHA----EKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQL 1204
+E E+ +E E+ L E RE+ R+ + ++ +Q E +L E +++
Sbjct: 924 QEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRR 983
Query: 1205 VEKEVKMREKQ 1215
E+E K RE++
Sbjct: 984 QEREKKYREEE 994
Score = 32.0 bits (71), Expect = 4.2
Identities = 24/99 (24%), Positives = 52/99 (52%), Gaps = 8/99 (8%)
Query: 1148 IEEMEKMLKEAHAEKNRLMESREREMELR----RQALEEERRRRE--QVERRLQSESARR 1201
+EE +++ ++ K R E R +E E + Q L ++R+R+ Q E++L+ + +
Sbjct: 1488 LEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQ 1547
Query: 1202 QQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIE 1240
Q+ +++ K RE++ Q R + +++ D K +E
Sbjct: 1548 QRRQDRDRKFREEE--QLRQEREEQQLSRQERDRKFRLE 1584
Score = 31.6 bits (70), Expect = 5.5
Identities = 22/82 (26%), Positives = 43/82 (52%), Gaps = 10/82 (12%)
Query: 1137 MSSASGLDMGK---IEEMEKMLKEAHAEKN-RLMESREREMELRRQALEEERRRREQVER 1192
+ A+GLD K + E +L++ E++ R E R+R++E EE +RR Q +
Sbjct: 89 LGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLE------EEPGQRRRQKRQ 142
Query: 1193 RLQSESARRQQLVEKEVKMREK 1214
+ E A ++ EK+ ++ ++
Sbjct: 143 EQERELAEGEEQSEKQERLEQR 164
Score = 31.2 bits (69), Expect = 7.2
Identities = 21/70 (30%), Positives = 40/70 (57%), Gaps = 3/70 (4%)
Query: 1169 REREM-ELRRQALEE-ERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYL 1226
R RE+ ELRR+ EE +++RRE+ +R Q E + + E ++ E++ + P R
Sbjct: 211 RRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEP-QRQR 269
Query: 1227 PIRKEDFDLK 1236
+++E+ L+
Sbjct: 270 ELQEEEEQLR 279
Score = 31.2 bits (69), Expect = 7.2
Identities = 19/78 (24%), Positives = 37/78 (47%), Gaps = 2/78 (2%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKE 1208
E K L+E + E +L ++ E++ R+E+ + L+ E R+Q E++
Sbjct: 1443 ERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQ--ERD 1500
Query: 1209 VKMREKQFSQARPLTRYL 1226
K RE++ P ++L
Sbjct: 1501 RKFREQELRSQEPERKFL 1518
Score = 31.2 bits (69), Expect = 7.2
Identities = 20/80 (25%), Positives = 41/80 (51%), Gaps = 8/80 (10%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSE--------SAR 1200
+E ++ +E + E + R E R+ EEE+ R+E+ E++L+ +
Sbjct: 1767 QERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826
Query: 1201 RQQLVEKEVKMREKQFSQAR 1220
+ QL E+E ++R+++ Q R
Sbjct: 1827 QLQLEEQEQRLRQERDRQYR 1846
>gi|41406064 myosin, heavy polypeptide 10, non-muscle [Homo sapiens]
Length = 1976
Score = 75.5 bits (184), Expect = 3e-13
Identities = 168/754 (22%), Positives = 301/754 (39%), Gaps = 124/754 (16%)
Query: 574 ERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEA 633
E + +I NE ++ H + +E+L E+E R ++ +LE + + A
Sbjct: 932 EEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGAR-QKLQLEKVT------AEAKIKKME 984
Query: 634 GELPSIGEATAALALAGRRPSRGLAGASGRSSEEP----GVATQRLWESMERSD-EENLK 688
E+ + + + + +A S + +EE +A R + + SD EE LK
Sbjct: 985 EEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKAKNLAKIRNKQEVMISDLEERLK 1044
Query: 689 EECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQ------ 742
+E E T+QE E A KL GE L+++ A++ +++LK+++ + E++LQ
Sbjct: 1045 KE----EKTRQELEKA-KRKLDGETTDLQDQIAELQAQIDELKLQLAKKEEELQGALARG 1099
Query: 743 -----------ESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKER 791
+ RE + + A LQ + E+E+A K +K L E+L AL+T ++
Sbjct: 1100 DDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKRDLSEELEALKTELEDTL 1159
Query: 792 DKEA-----------------EALETETK---------------LFEDLEFQQLERESRV 819
D A +ALE ETK E+L +QLE+ R
Sbjct: 1160 DTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHATALEELS-EQLEQAKRF 1218
Query: 820 EEERELAGQGLLRSKAELLRSI-------AKRKERLAILDSQAGQIRAQAVQESERLARD 872
+ E QGL EL + A+ + + LD+Q ++ A+ V E +RL +
Sbjct: 1219 KANLEKNKQGLETDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAK-VSEGDRLRVE 1277
Query: 873 KNASLQLLQKEKEKLTVL--ERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQEL 930
LQ E + ++ L E + + S L++ ++LL E+ Q+L
Sbjct: 1278 LAEKASKLQNELDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELL-----QEETRQKL 1332
Query: 931 MAGLGTGPAAASPHS----SPPPLPAKASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSG 986
+S A+ + + QV + T G + S
Sbjct: 1333 NLSSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQLADTKKKVDDDLGTIESLEE 1392
Query: 987 SSSSSSQLSVATLGRSPSPKSAL-LTQNGTGSLPRNLAATLQDIETKRQLA-----LQQK 1040
+ + + A R A + L + L D++ +RQ+A Q+K
Sbjct: 1393 AKKKLLKDAEALSQRLEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKK 1452
Query: 1041 GQQVIEEQR---RRLAELKQKAAAEA-QCQWDALHGAAPFPAGPSGFPPLMHHSILHHLP 1096
Q++ E++ R AE + +A AEA + + AL S+ L
Sbjct: 1453 FDQLLAEEKSISARYAEERDRAEAEAREKETKAL-------------------SLARALE 1493
Query: 1097 AGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLK 1156
E EE E L + D M + G N + S L+ ++EEM L+
Sbjct: 1494 EALEAKEEFERQNKQLRADMEDLMSSKDDVGKN---VHELEKSKRALEQ-QVEEMRTQLE 1549
Query: 1157 EAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARR---QQLVEKEVKMRE 1213
E E +++ R +E+ QA++ + R Q R Q+E +R +Q+ E E ++ +
Sbjct: 1550 ELEDELQATEDAKLR-LEVNMQAMKAQFERDLQT-RDEQNEEKKRLLIKQVRELEAELED 1607
Query: 1214 KQFSQARPLTRYLPIRKEDFDLKTHIESSGHGVD 1247
++ +A + + + DL+ IE++ D
Sbjct: 1608 ERKQRALAVASKKKMEIDLKDLEAQIEAANKARD 1641
Score = 68.6 bits (166), Expect = 4e-11
Identities = 146/715 (20%), Positives = 285/715 (39%), Gaps = 101/715 (14%)
Query: 583 SDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLC-AEYSRADGGPEAGELPSIGE 641
+DN++ E Q+ + E + ++L+ Q E + + R + +A +L + E
Sbjct: 1231 TDNKELACEVKVLQQVKAESEHKRKKLDAQVQELHAKVSEGDRLRVELAEKASKLQN--E 1288
Query: 642 ATAALALAGRRPSRGLAGASGRSSEEPGVA-TQRLWESMER------SDEENLKEECSST 694
L +G+ A +S E + TQ L + R S L+EE +S
Sbjct: 1289 LDNVSTLLEEAEKKGIKFAKDAASLESQLQDTQELLQEETRQKLNLSSRIRQLEEEKNSL 1348
Query: 695 ESTQQEHEDAPSTKLQGEVLALEEERAQV-------LGHVEQLKVRVKEL-------EQQ 740
+ Q+E E+A L+ +VLAL+ + A LG +E L+ K+L Q+
Sbjct: 1349 QEQQEEEEEARKN-LEKQVLALQSQLADTKKKVDDDLGTIESLEEAKKKLLKDAEALSQR 1407
Query: 741 LQESAR---EAEMERALLQGE----------REAERALLQKEQKAVDQLQEKLVALETGI 787
L+E A + E + LQ E + + L+K+QK DQL + ++
Sbjct: 1408 LEEKALAYDKLEKTKNRLQQELDDLTVDLDHQRQVASNLEKKQKKFDQLLAEEKSISARY 1467
Query: 788 QKERDK-EAEALETETKLFEDLEFQQLERESRVEEERELAG-----QGLLRSKAELLRSI 841
+ERD+ EAEA E ETK + E++ E ER+ + L+ SK ++ +++
Sbjct: 1468 AEERDRAEAEAREKETKALSLARALEEALEAKEEFERQNKQLRADMEDLMSSKDDVGKNV 1527
Query: 842 AKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQL--------------------LQ 881
+ ++ L+ Q ++R Q + + L ++A L+L
Sbjct: 1528 HELEKSKRALEQQVEEMRTQLEELEDELQATEDAKLRLEVNMQAMKAQFERDLQTRDEQN 1587
Query: 882 KEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAA 941
+EK++L + + R + + +K+ + DLE + AA
Sbjct: 1588 EEKKRLLIKQVRELEAELEDERKQRALAVASKKKMEIDLKDLEAQIE----------AAN 1637
Query: 942 SPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGR 1001
K Q++ Y+ +++ S R S S L L
Sbjct: 1638 KARDEVIKQLRKLQAQMKDYQRELEEARAS-----RDEIFAQSKESEKKLKSLEAEIL-- 1690
Query: 1002 SPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRL----AELKQ 1057
L + + R A +D E ++ G+ + +++RRL A+L++
Sbjct: 1691 ------QLQEELASSERARRHAEQERD-ELADEITNSASGKSALLDEKRRLEARIAQLEE 1743
Query: 1058 KAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESS 1117
+ E Q + L+ L ++ L A R ++ ++A L ++
Sbjct: 1744 ELEEE-QSNMELLNDRFRKTT-------LQVDTLNAELAAERSAAQKSDNARQQLERQNK 1795
Query: 1118 DSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRR 1177
+ G SA +G++EE + + A N+L+ E++++
Sbjct: 1796 ELKAKLQELEGAVKSKFKATISALEAKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIF 1855
Query: 1178 QALEEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKED 1232
+E+ERR +Q + +++ +AR +QL +++++ E++ ++A R L +D
Sbjct: 1856 MQVEDERRHADQYKEQMEKANARMKQL-KRQLEEAEEEATRANASRRKLQRELDD 1909
Score = 57.0 bits (136), Expect = 1e-07
Identities = 58/229 (25%), Positives = 108/229 (47%), Gaps = 36/229 (15%)
Query: 687 LKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESA- 745
L+EE +S+E ++ H + +L E+ ++ +L +L+ R+ +LE++L+E
Sbjct: 1692 LQEELASSERARR-HAEQERDELADEITNSASGKSALLDEKRRLEARIAQLEEELEEEQS 1750
Query: 746 ---------REAEMERALLQGEREAERALLQKEQKAVDQLQE-------KLVALETGIQK 789
R+ ++ L E AER+ QK A QL+ KL LE ++
Sbjct: 1751 NMELLNDRFRKTTLQVDTLNAELAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKS 1810
Query: 790 ERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAEL----------LR 839
+ ALE + E +QLE+E++ ER A + + R++ +L R
Sbjct: 1811 KFKATISALEAKIGQLE----EQLEQEAK---ERAAANKLVRRTEKKLKEIFMQVEDERR 1863
Query: 840 SIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLT 888
+ KE++ +++ Q++ Q ++E+E A NAS + LQ+E + T
Sbjct: 1864 HADQYKEQMEKANARMKQLKRQ-LEEAEEEATRANASRRKLQRELDDAT 1911
Score = 48.9 bits (115), Expect = 3e-05
Identities = 110/547 (20%), Positives = 220/547 (40%), Gaps = 56/547 (10%)
Query: 707 TKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGERE--AERA 764
T+ + E+ A +EE +V +++ ++E+E++ Q+ E + LQ E E AE
Sbjct: 848 TRQEEELQAKDEELLKVKEKQTKVEGELEEMERKHQQLLEEKNILAEQLQAETELFAEAE 907
Query: 765 LLQKEQKAVDQ-LQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEER 823
++ A Q L+E L LE+ +++E ++ + L+ E K + Q LE + +E
Sbjct: 908 EMRARLAAKKQELEEILHDLESRVEEEEERN-QILQNEKKKMQ-AHIQDLEEQL---DEE 962
Query: 824 ELAGQGLLRSKAELLRSIAKRKERLAILDSQ--------------AGQIRAQAVQESER- 868
E A Q L K I K +E + +L+ Q + +Q +E E+
Sbjct: 963 EGARQKLQLEKVTAEAKIKKMEEEILLLEDQNSKFIKEKKLMEDRIAECSSQLAEEEEKA 1022
Query: 869 --LARDKNASLQLLQKEKEKLTVLERRYHSL-TGGRPFPKTTSTLKEMEKLLLPAVD--- 922
LA+ +N ++ +E+L E+ L R T+ L++ L +D
Sbjct: 1023 KNLAKIRNKQEVMISDLEERLKKEEKTRQELEKAKRKLDGETTDLQDQIAELQAQIDELK 1082
Query: 923 --LEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATS-----PLPR 975
L + +EL L G ++ + + Q+ + + E S R
Sbjct: 1083 LQLAKKEEELQGALARGDDETLHKNNALKVVRELQAQIAELQEDFESEKASRNKAEKQKR 1142
Query: 976 TRSGPLPSSSGSSSSSSQLSVATLG-RSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQ 1034
S L + + + A R+ + + +N A +QD+ +
Sbjct: 1143 DLSEELEALKTELEDTLDTTAAQQELRTKREQEVAELKKALEEETKNHEAQIQDMRQRHA 1202
Query: 1035 LALQQKGQQVIEEQRRRLAELKQKAAA------EAQCQWDALHGAAPFPAGPSGFPPLMH 1088
AL++ +Q +E+ +R A L++ E C+ L S
Sbjct: 1203 TALEELSEQ-LEQAKRFKANLEKNKQGLETDNKELACEVKVLQQV----KAESEHKRKKL 1257
Query: 1089 HSILHHLPAGRERGE--EGEHAYDTLSLESS-DSMETSISTGGNSACSPDNMSSASGLDM 1145
+ + L A G+ E A L++ D++ T + A+ L+
Sbjct: 1258 DAQVQELHAKVSEGDRLRVELAEKASKLQNELDNVSTLLEEAEKKGIK--FAKDAASLE- 1314
Query: 1146 GKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSE-SARRQQL 1204
++++ +++L+E +K L SR R++E + +L+E++ E+ + L+ + A + QL
Sbjct: 1315 SQLQDTQELLQEETRQKLNL-SSRIRQLEEEKNSLQEQQEEEEEARKNLEKQVLALQSQL 1373
Query: 1205 VEKEVKM 1211
+ + K+
Sbjct: 1374 ADTKKKV 1380
Score = 39.3 bits (90), Expect = 0.026
Identities = 47/222 (21%), Positives = 94/222 (42%), Gaps = 33/222 (14%)
Query: 670 VATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQ 729
+A +R + + L+ + ++ QE E A +K + + ALE
Sbjct: 1773 LAAERSAAQKSDNARQQLERQNKELKAKLQELEGAVKSKFKATISALE------------ 1820
Query: 730 LKVRVKELEQQLQESARE-AEMERALLQGEREAERALLQ--KEQKAVDQLQEKLVALETG 786
++ +LE+QL++ A+E A + + + E++ + +Q E++ DQ +E++
Sbjct: 1821 --AKIGQLEEQLEQEAKERAAANKLVRRTEKKLKEIFMQVEDERRHADQYKEQMEKANAR 1878
Query: 787 IQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKE 846
+++ + + EA E T+ SR + +REL + L R ++ K
Sbjct: 1879 MKQLKRQLEEAEEEATR----------ANASRRKLQREL--DDATEANEGLSREVSTLKN 1926
Query: 847 RLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLT 888
RL + G I + + R + ASL+L + E T
Sbjct: 1927 RL----RRGGPISFSSSRSGRRQLHLEGASLELSDDDTESKT 1964
Score = 35.4 bits (80), Expect = 0.38
Identities = 31/109 (28%), Positives = 49/109 (44%), Gaps = 20/109 (18%)
Query: 1146 GKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRR------------EQVERR 1193
G++EEME+ ++ EKN L E + E EL +A EE R R +E R
Sbjct: 873 GELEEMERKHQQLLEEKNILAEQLQAETELFAEA--EEMRARLAAKKQELEEILHDLESR 930
Query: 1194 LQSESARRQQLVEKEVKMR------EKQFSQARPLTRYLPIRKEDFDLK 1236
++ E R Q L ++ KM+ E+Q + + L + K + K
Sbjct: 931 VEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVTAEAK 979
Score = 34.3 bits (77), Expect = 0.85
Identities = 21/81 (25%), Positives = 45/81 (55%), Gaps = 9/81 (11%)
Query: 1147 KIEEMEKMLK------EAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESAR 1200
K +E+E++L E E+N+++++ +++M+ Q LEE+ E ++LQ E
Sbjct: 916 KKQELEEILHDLESRVEEEEERNQILQNEKKKMQAHIQDLEEQLDEEEGARQKLQLEKVT 975
Query: 1201 RQ---QLVEKEVKMREKQFSQ 1218
+ + +E+E+ + E Q S+
Sbjct: 976 AEAKIKKMEEEILLLEDQNSK 996
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 73.2 bits (178), Expect = 2e-12
Identities = 119/437 (27%), Positives = 151/437 (34%), Gaps = 73/437 (16%)
Query: 146 PAGGRAPGPPYSPVPAESESLVNGNHTPQ---TATRGPSACASHSSLVSSIEKDLQEIMD 202
PA P PP + P +S S + + T + A R PSA S +
Sbjct: 183 PAPSARPRPP-TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 241
Query: 203 SLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPA 262
S P A G A P P G + L P +P ++ +PA PLSS
Sbjct: 242 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPR-------KDAAPALGPLSS-- 292
Query: 263 SSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPSGARSESPRLSRKGGHERP 322
A+ SPS P PS PP + S PP + PS A + + + H
Sbjct: 293 --SPLATPSPSAP-PSPSAPPSLQTLPS-------PPATPPSQATTSLGSPTLQATHSFL 342
Query: 323 PSPGLRGLLT---DSPAATVLAEARR-------------ATESPRLGGQLPVVAISLS-- 364
PSP L L T +P A L + AT SP+ L V +
Sbjct: 343 PSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 402
Query: 365 ---EYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSPS 421
P S P S P SP PP AP + PPSP PP S + +P
Sbjct: 403 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP---SATPP 459
Query: 422 RQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELP-------PLSPSLSRRALSPLPT 474
Q + L P P L L ++ P P SPS S +SPL T
Sbjct: 460 PQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS-LPMSPLAT 518
Query: 475 RTTPDPKLNR----EVAESP-------RPRRWAAHGASPE------DFSLTLGARGRRTR 517
P + +V SP PRR G +L G +R
Sbjct: 519 PPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSR 578
Query: 518 SPSPTL-GESLAPHKGS 533
SPS TL G LA H S
Sbjct: 579 SPSSTLSGPDLAGHSSS 595
Score = 67.8 bits (164), Expect = 7e-11
Identities = 126/453 (27%), Positives = 169/453 (37%), Gaps = 71/453 (15%)
Query: 143 SMIPAGGRAPGPPYSP-VPAESESLVNGNHTPQ----TATRGPSACASHSSL----VSSI 193
S P +P P SP P ++L + TP T+ P+ A+HS L +S +
Sbjct: 291 SSSPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPL 350
Query: 194 EKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSP 253
+ +L L P A P A+ PLSP+A P +P A++V SP
Sbjct: 351 ATPPPQAPPALALP-PLQAPPSPPASPPLSPLATPS------PQAPNALAVHLLQAPFSP 403
Query: 254 A--------FSPLSSPASSGSCASHS---PSGQEPGPSVPPLVPARSSSYHLALQPPQSR 302
FSP +SP S S S PS P VPP PA A PPQ+
Sbjct: 404 PPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAP 463
Query: 303 PSGARSESPRLSRKGGHERPPS---PGLRGLLTDSPAATVLAEARRATESPRLGGQLPVV 359
P A P K + PP+ P L+ L SP A+ +A SP + +
Sbjct: 464 PPLAAP--PLQLAKPPPQAPPALATPPLQAL--PSPPASFPGQA---PFSPSASLPMSPL 516
Query: 360 AISLSEYP---ASGALSQPTSIPGSPKFQ----PPVPAPRNKIG----TLQDRPPSPFRE 408
A + P A+ L P S P SP Q PP P P + TL P P
Sbjct: 517 ATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP--- 573
Query: 409 PPGSERVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRE-----LPPLSPS 463
PP S SPS L G + ++ T P E RG DS E PP P
Sbjct: 574 PPPSR-----SPSSTLSGPDLAGHSSSATSTPEE-----LRGYDSGPEGGAAASPP--PD 621
Query: 464 LSRRALSPLPTRTTPDPKLN-REVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPT 522
A P P P L R +P P A S + G + +P+P
Sbjct: 622 AELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPG 681
Query: 523 LGESLAPHKGSFSGRLSPAYSLGSLTGASPCQS 555
+ P G+ G+ + G+ + SP Q+
Sbjct: 682 ALDP-GPSPGTSGGKAAAGAGAGA-SSRSPKQA 712
Score = 32.7 bits (73), Expect = 2.5
Identities = 41/161 (25%), Positives = 59/161 (36%), Gaps = 31/161 (19%)
Query: 933 GLGTGPAAASPHSSPPPLPAK---------ASRQLQVYRSKMDGEATSPLPRTRSGPLPS 983
GL T SP PP PA R+ R+ G AT P R+GP +
Sbjct: 23 GLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGGATIPESAPRAGPTRT 82
Query: 984 SSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQ 1043
S +S + + SP P S+ +G T R L QKG +
Sbjct: 83 SRPPASGRGERAPPAKNTSPGPVSSPGRASG----------------TTRPGPLGQKGLR 126
Query: 1044 VIEEQ---RRRLAELKQKAAAEAQCQWDALHGAAPFPAGPS 1081
+ E+ R + E +++A A + D + P P PS
Sbjct: 127 ISAEETVARGKATEAPKRSALSAGARRDT---SGPTPGTPS 164
>gi|71361682 nuclear mitotic apparatus protein 1 [Homo sapiens]
Length = 2115
Score = 73.2 bits (178), Expect = 2e-12
Identities = 155/678 (22%), Positives = 257/678 (37%), Gaps = 93/678 (13%)
Query: 574 ERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEA 633
E++ I+E+ L+E H+R+R +E E ER R+ LE L E +A+
Sbjct: 731 EQQRCISELKAETRSLVEQHKRER----KELEEERAGRKGLEARLQQLGEAHQAETEVLR 786
Query: 634 GELPSIGEATAALALAGRRPSRGLAG-ASGRSSEEPGVATQRLWESMERSDEENLKEECS 692
EL EA AA A + + A+ R E + + +M + LKEEC
Sbjct: 787 REL---AEAMAAQHTAESECEQLVKEVAAWRERYEDSQQEEAQYGAMFQEQLMTLKEECE 843
Query: 693 STESTQQE----------HEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQL- 741
QE H + ++ Q E+ L A+ L V++ +VR ++L L
Sbjct: 844 KARQELQEAKEKVAGIESHSELQISRQQNELAELHANLARALQQVQEKEVRAQKLADDLS 903
Query: 742 ----------QESAREAEMERALLQGEREAERALLQKEQKAVDQLQE--------KLVAL 783
+E AR + R + + A R L+++ +A D+ E + +
Sbjct: 904 TLQEKMAATSKEVARLETLVRKAGEQQETASRELVKEPARAGDRQPEWLEEQQGRQFCST 963
Query: 784 ETGIQ-KERDKEAEALETETKLFEDLEFQQLERESRVEEERELA--GQGLLRSKAELLRS 840
+ +Q ER+ E E E +E Q ++E R ++ERE+A Q R++A+L
Sbjct: 964 QAALQAMEREAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALE 1023
Query: 841 IAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGG 900
A R E L + + R + E LA L +KE + + + R
Sbjct: 1024 KAARAELEMRLQNALNEQRVEFATLQEALAH------ALTEKEGKDQELAKLRGLEAAQI 1077
Query: 901 RPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGT-GPAAASPHSSPPPLPA------K 953
+ + T+K++++ L + +E +G G AA + P L A K
Sbjct: 1078 KELEELRQTVKQLKE------QLAKKEKEHASGSGAQSEAAGRTEPTGPKLEALRAEVSK 1131
Query: 954 ASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQL--SVATLGRSPSPKSALLT 1011
+Q Q + + D S L R+ S + QL LG S
Sbjct: 1132 LEQQCQKQQEQADSLERS-LEAERASRAERDSALETLQGQLEEKAQELGHS--------- 1181
Query: 1012 QNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALH 1071
Q+ S R LAA ++ + + K Q + R+ AE K + + + L+
Sbjct: 1182 QSALASAQRELAAFRTKVQDHSKAEDEWKAQVA---RGRQEAERKNSLISSLEEEVSILN 1238
Query: 1072 GAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSA 1131
G S + + A E+ ++ E L E T NSA
Sbjct: 1239 RQVLEKEGES-------KELKRLVMAESEKSQKLEERLRLLQAE----------TASNSA 1281
Query: 1132 CSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQ--ALEEERRRREQ 1189
+ + S+ EE EK + + L ER EL ++ A +E+ ++EQ
Sbjct: 1282 RAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQKEQ 1341
Query: 1190 VERRLQSESARRQQLVEK 1207
LQ E Q LV +
Sbjct: 1342 ALSTLQLEHTSTQALVSE 1359
Score = 66.2 bits (160), Expect = 2e-10
Identities = 158/773 (20%), Positives = 296/773 (38%), Gaps = 139/773 (17%)
Query: 539 SPAYSLGSLTGASPCQSPCVQRKLSS-----GDLRVPVTRERK------NSITEISDNED 587
SPA +G + Q ++++L+ +L + + RK I + D
Sbjct: 200 SPASPMGDILQTPQFQMRRLKKQLADERSNRDELELELAENRKLLTEKDAQIAMMQQRID 259
Query: 588 DLLEYHRRQRQERLREQEMERLERQ------RLETILNLCAEYSRADGGPEAGELPSIGE 641
L + +Q L +E+E L + RL L C + + + ++ + E
Sbjct: 260 RLALLNEKQAASPLEPKELEELRDKNESLTMRLHETLKQCQDL-KTEKSQMDRKINQLSE 318
Query: 642 ATAALALAGRRPS---RGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQ 698
L+ R + + L A +EE ATQ W + E+ L + +
Sbjct: 319 ENGDLSFKLREFASHLQQLQDALNELTEEHSKATQE-WLEKQAQLEKELSAALQDKKCLE 377
Query: 699 QEHEDAPSTKLQGEVLALEE-----------ERAQVLGHVEQLKVRVKEL------EQQL 741
+++E LQG++ LEE E+ +VLG V QL+ +E QL
Sbjct: 378 EKNEI-----LQGKLSQLEEHLSQLQDNPPQEKGEVLGDVLQLETLKQEAATLAANNTQL 432
Query: 742 QESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETE 801
Q E ER + + AER ++E++ + L L + + + + +++ +A +
Sbjct: 433 QARVEMLETERGQQEAKLLAERGHFEEEKQQLSSLITDLQSSISNLSQAKEELEQASQAH 492
Query: 802 --------------------TKLFEDLEFQQLERESRVE--------EERELAGQGL--- 830
T +D E L+++++ + +++E A QGL
Sbjct: 493 GARLTAQVASLTSELTTLNATIQQQDQELAGLKQQAKEKQAQLAQTLQQQEQASQGLRHQ 552
Query: 831 -------LRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNAS---LQLL 880
L+ K + L+ +A+++E A A Q+ A A +E E R+++A+ L+ L
Sbjct: 553 VEQLSSSLKQKEQQLKEVAEKQE--ATRQDHAQQL-ATAAEEREASLRERDAALKQLEAL 609
Query: 881 QKEK-EKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTG-- 937
+KEK KL +L+++ R +T+ T + EK +L + +EL A + T
Sbjct: 610 EKEKAAKLEILQQQLQVANEARDSAQTSVTQAQREK-----AELSRKVEELQACVETARQ 664
Query: 938 ---PAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQL 994
A A L ++ + + R + + + L + GS +
Sbjct: 665 EQHEAQAQVAELELQLRSEQQKATEKERVAQEKDQLQEQLQALKESLKVTKGSLEEEKRR 724
Query: 995 SVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKR------QLALQQKG---QQVI 1045
+ L S L + T SL +++E +R + LQQ G Q
Sbjct: 725 AADALEEQQRCISELKAE--TRSLVEQHKRERKELEEERAGRKGLEARLQQLGEAHQAET 782
Query: 1046 EEQRRRLAE-LKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEE 1104
E RR LAE + + AE++C+ ++ + A RER E+
Sbjct: 783 EVLRRELAEAMAAQHTAESECE-----------------------QLVKEVAAWRERYED 819
Query: 1105 G---EHAYDTLSLESSDSMETSISTGGNSAC-SPDNMSSASGLDMGKIEEMEKMLKEAHA 1160
E Y + E +++ + + ++ +I + L E HA
Sbjct: 820 SQQEEAQYGAMFQEQLMTLKEECEKARQELQEAKEKVAGIESHSELQISRQQNELAELHA 879
Query: 1161 EKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKEVKMRE 1213
R ++ + +E E+R Q L ++ ++ E AR + LV K + +E
Sbjct: 880 NLARALQ-QVQEKEVRAQKLADDLSTLQEKMAATSKEVARLETLVRKAGEQQE 931
Score = 61.6 bits (148), Expect = 5e-09
Identities = 115/518 (22%), Positives = 202/518 (38%), Gaps = 69/518 (13%)
Query: 573 RERKNSITEISDNEDDLLEYHRRQRQER-LREQEMERLERQRLETILNLCAEYSRADGGP 631
RE + E+ L+E +Q++ER +E+E+ RL ++R +L E + A
Sbjct: 972 REAEQMGNELERLRAALMESQGQQQEERGQQEREVARLTQERGRAQADLALEKA-ARAEL 1030
Query: 632 EAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEEC 691
E ++ E A + L G+ E +A R E+ + + E L++
Sbjct: 1031 EMRLQNALNEQRVEFATLQEALAHALTEKEGKDQE---LAKLRGLEAAQIKELEELRQTV 1087
Query: 692 SSTES--TQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAE 749
+ ++E E A + Q E E L E L+ V +LEQQ Q+ +A+
Sbjct: 1088 KQLKEQLAKKEKEHASGSGAQSEAAGRTEPTGPKL---EALRAEVSKLEQQCQKQQEQAD 1144
Query: 750 -MERAL----------------LQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERD 792
+ER+L LQG+ E + L Q A+ Q +L A T +Q
Sbjct: 1145 SLERSLEAERASRAERDSALETLQGQLEEKAQELGHSQSALASAQRELAAFRTKVQ---- 1200
Query: 793 KEAEALETETKLFEDLEFQQLERE----SRVEEERELAGQGLLRSKA---ELLRSIAKRK 845
+ E E K Q+ ER+ S +EEE + + +L + EL R +
Sbjct: 1201 -DHSKAEDEWKAQVARGRQEAERKNSLISSLEEEVSILNRQVLEKEGESKELKRLVMAES 1259
Query: 846 ERLAILDSQAGQIRAQAVQESERLARDKNA---SLQLLQKEKEKLTVLERRYHSLTGGRP 902
E+ L+ + ++A+ S R A +A +Q L++E EK V
Sbjct: 1260 EKSQKLEERLRLLQAETASNSARAAERSSALREEVQSLREEAEKQRVASENLRQ------ 1313
Query: 903 FPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPP-----LPAK-ASR 956
+ TS + E+L +L+ W ++ H+S LPAK +
Sbjct: 1314 --ELTSQAERAEEL---GQELKAWQEKFFQKEQALSTLQLEHTSTQALVSELLPAKHLCQ 1368
Query: 957 QLQVYRSKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTG 1016
QLQ ++ + L +++ ++G + + LG + + Q T
Sbjct: 1369 QLQAEQAAAEKRHREELEQSK-----QAAGGLRAELLRAQRELGELIPLRQKVAEQERTA 1423
Query: 1017 SLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAE 1054
R A+ + QL++ +K ++ E+ R L E
Sbjct: 1424 QQLRAEKASYAE-----QLSMLKKAHGLLAEENRGLGE 1456
Score = 45.4 bits (106), Expect = 4e-04
Identities = 94/383 (24%), Positives = 159/383 (41%), Gaps = 46/383 (12%)
Query: 673 QRLWESMERSDEENLKEECSSTESTQQEHE--------DAPSTKLQGEVLALEEERAQVL 724
QR E ++ + + E E T+Q E D S Q ++ A++ + +
Sbjct: 1524 QRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQGGESQ 1583
Query: 725 GHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALE 784
++L+ ++ EL+ QL S +E E LQ E+ +K+Q +LQE+L +LE
Sbjct: 1584 QEAQRLQAQLNELQAQL--SQKEQAAEHYKLQMEKAKTHYDAKKQQN--QELQEQLRSLE 1639
Query: 785 TGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKR 844
++ ++ AEA +L +L+ L+ + + R L Q +RS L +A
Sbjct: 1640 QLQKENKELRAEA----ERLGHELQQAGLKTKEAEQTCRHLTAQ--VRS---LEAQVAHA 1690
Query: 845 KERLAILDSQAGQIRAQAVQESERLARDK----NASLQLLQKEKEKLTVLERRYHSLTGG 900
++L D Q+ A++ E A+ + SL L +E L++ + + G
Sbjct: 1691 DQQLR--DLGKFQVATDALKSREPQAKPQLDLSIDSLDLSCEEGTPLSITSKLPRTQPDG 1748
Query: 901 RPFPKTTSTLKEMEKLLLPAVD-LEQWYQELMAGLGTGPAAASPHS-------SPPPLPA 952
P ++ + + L P V+ LE Y + P +S S S +
Sbjct: 1749 TSVPGEPAS--PISQRLPPKVESLESLYFTPIPARSQAPLESSLDSLGDVFLDSGRKTRS 1806
Query: 953 KASRQLQVYR----SKMDGE----ATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPS 1004
R Q+ K+D E A S TRS P +S ++SS+Q S+A LG
Sbjct: 1807 ARRRTTQIINITMTKKLDVEEPDSANSSFYSTRSAPASQASLRATSSTQ-SLARLGSPDY 1865
Query: 1005 PKSALLTQNGTGSLPRNLAATLQ 1027
SALL+ G R+ A Q
Sbjct: 1866 GNSALLSLPGYRPTTRSSARRSQ 1888
Score = 45.1 bits (105), Expect = 5e-04
Identities = 89/387 (22%), Positives = 151/387 (39%), Gaps = 78/387 (20%)
Query: 574 ERKNSITEISDNEDDLLEYHRRQRQERLREQEMERL------ERQRLETILNLCAEYSRA 627
ERKNS+ IS E+++ +R+ ++ +E++RL + Q+LE L L + +
Sbjct: 1221 ERKNSL--ISSLEEEVSILNRQVLEKEGESKELKRLVMAESEKSQKLEERLRLLQAETAS 1278
Query: 628 DGGPEAG-------ELPSIGEATAALALAGRRPSRGLAGASGRSSE-------------- 666
+ A E+ S+ E +A + L + R+ E
Sbjct: 1279 NSARAAERSSALREEVQSLREEAEKQRVASENLRQELTSQAERAEELGQELKAWQEKFFQ 1338
Query: 667 -EPGVATQRLWESMERSDEENL---KEECSSTESTQ-----QEHEDAPSTKLQGEVLALE 717
E ++T +L + ++ L K C ++ Q + E+ +K L E
Sbjct: 1339 KEQALSTLQLEHTSTQALVSELLPAKHLCQQLQAEQAAAEKRHREELEQSKQAAGGLRAE 1398
Query: 718 EERAQ-VLGHVEQLKVRVKELEQQLQESARE------------------AEMERALLQ-- 756
RAQ LG + L+ +V E E+ Q+ E AE R L +
Sbjct: 1399 LLRAQRELGELIPLRQKVAEQERTAQQLRAEKASYAEQLSMLKKAHGLLAEENRGLGERA 1458
Query: 757 --GEREAERALLQKEQKAVDQLQEKLVALETG---IQKERDKEAEALETETKLFEDLEFQ 811
G + E L Q +K V +L ET +Q+E A LE T +E + +
Sbjct: 1459 NLGRQFLEVELDQAREKYVQELAAVRADAETRLAEVQREAQSTARELEVMTAKYEGAKVK 1518
Query: 812 QLERESRVEEER----------ELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQ 861
LE R +EER E+ + + EL + +A + + + ++AQ
Sbjct: 1519 VLEERQRFQEERQKLTAQVEQLEVFQREQTKQVEELSKKLADSDQASKVQQQKLKAVQAQ 1578
Query: 862 ---AVQESERLARDKN-ASLQLLQKEK 884
+ QE++RL N QL QKE+
Sbjct: 1579 GGESQQEAQRLQAQLNELQAQLSQKEQ 1605
>gi|41322923 plectin 1 isoform 11 [Homo sapiens]
Length = 4547
Score = 73.2 bits (178), Expect = 2e-12
Identities = 142/692 (20%), Positives = 275/692 (39%), Gaps = 80/692 (11%)
Query: 566 DLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYS 625
+L + + R R N+ + E LE RQRQ E+ R +R++ L E +
Sbjct: 1943 ELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAEERVQKSLAAEEEAA 2001
Query: 626 RADGGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEE 685
R L + A + A R R S R + A Q+ ++ E++
Sbjct: 2002 RQ----RKAALEEVERLKAKVEEARRLRERA-EQESARQLQLAQEAAQKRLQAEEKAHAF 2056
Query: 686 NLKEECSSTESTQQEHEDAPSTKLQGEVLAL-------EEERAQVLGHVEQLKVRVKELE 738
++++ + T Q+ E + +L+GE A EE R Q Q + +V+E E
Sbjct: 2057 AVQQKEQELQQTLQQ-EQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE 2115
Query: 739 QQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVAL------ETGIQKERD 792
+ L++SA E RA Q + AE+ + EQ+A + Q + AL + ++K +
Sbjct: 2116 R-LKQSAEEQAQARA--QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2172
Query: 793 KEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKE------ 846
+ L + ++ ++L +L+ E + ++ L + L R KAE + +R +
Sbjct: 2173 FAEQTLRQKAQVEQELTTLRLQLE-ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELF 2231
Query: 847 RLAILDSQAGQIRAQAVQESERL-ARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPK 905
+ + + +++A+ E+ L RDK+ + + LQ+E EK+ + L+
Sbjct: 2232 SVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAA 2291
Query: 906 TTSTLKEMEKLLLPAVDLEQWYQELMAGLGTG---PAAASPHSSPPPLPAKASRQLQVYR 962
L E E L E+ +E M + A A L + +R+LQ +
Sbjct: 2292 RLRQLAE-EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK 2350
Query: 963 SKMD---GEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLP 1019
+M E T RT S+ + +L + S + A
Sbjct: 2351 EQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA----EEDAQRF 2406
Query: 1020 RNLAATLQDIETKRQLALQQKGQ--QVIEEQRRRL---AELKQKAAAEAQCQWDALHGAA 1074
R A + + + +LA Q+K Q +E QR++ AE ++A AE + + + L A
Sbjct: 2407 RKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEA 2466
Query: 1075 PFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSP 1134
+ + EE + L+ + +++ S + +S
Sbjct: 2467 KLL---------------------QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2505
Query: 1135 DNMSSASGLDMGKI------------EEMEKMLKEAHAEKNRLMESREREMELRRQALEE 1182
+ + ++ EE ++ ++ E+ RL+ S E + +A E
Sbjct: 2506 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2565
Query: 1183 ERRRREQVERRLQSESARRQQLVEKEVKMREK 1214
RR++E++++ Q + + L E+ ++RE+
Sbjct: 2566 VRRKQEELQQLEQQRRQQEELLAEENQRLREQ 2597
Score = 72.0 bits (175), Expect = 4e-12
Identities = 144/673 (21%), Positives = 276/673 (41%), Gaps = 81/673 (12%)
Query: 591 EYHRRQRQERLR-----EQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAA 645
E RR+ +ER++ E+E R + LE + L A+ A E E S + A
Sbjct: 1980 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLA 2039
Query: 646 LALAGRR-PSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDA 704
A +R + A A +E Q L +++++ ++ L + E+ ++ E+A
Sbjct: 2040 QEAAQKRLQAEEKAHAFAVQQKE-----QELQQTLQQ-EQSVLDQLRGEAEAARRAAEEA 2093
Query: 705 PSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAR-EAEMERALLQGEREAER 763
++Q E E AQ VE+ + + E+Q Q A+ +A E+ + E+EA R
Sbjct: 2094 EEARVQAE-----REAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2148
Query: 764 ALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEER 823
Q EQ A+ Q Q A + ++K + + L + ++ ++L +L+ E + ++
Sbjct: 2149 RA-QAEQAALRQKQ----AADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE-TDHQK 2202
Query: 824 ELAGQGLLRSKAELLRSIAKRKE------RLAILDSQAGQIRAQAVQESERLA-RDKNAS 876
L + L R KAE + +R + + + + +++A+ E+ L RDK+ +
Sbjct: 2203 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2262
Query: 877 LQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGT 936
+ LQ+E EK+ + L+ L E E L E+ +E M +
Sbjct: 2263 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAE-EDLAQQRALAEKMLKEKMQAVQE 2321
Query: 937 GP---AAASPHSSPPPLPAKASRQLQVYRSKMD---GEATSPLPRTRSGPLPSSSGSSSS 990
A A L + +R+LQ + +M E T RT S+
Sbjct: 2322 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2381
Query: 991 SSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQ--QVIEEQ 1048
+ +L + S + A R A + + + +LA Q+K Q +E Q
Sbjct: 2382 AERLKLRVAEMSRAQARA----EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ 2437
Query: 1049 RRRL---AELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEG 1105
R++ AE ++A AE + + + L A + + EE
Sbjct: 2438 RQQSDHDAERLREAIAELEREKEKLQQEAKLL---------------------QLKSEEM 2476
Query: 1106 EHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRL 1165
+ L+ + +++ S + +S + ++ K + +E++ ++ A+ +L
Sbjct: 2477 QTVQQEQLLQETQALQQSFLSEKDSLLQRERF-----IEQEKAK-LEQLFQDEVAKAQQL 2530
Query: 1166 MESRERE---MELRRQAL----EEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQ 1218
E ++R+ ME RQ L EE RRR+ + E ++ + QQL ++ + E +
Sbjct: 2531 REEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEE 2590
Query: 1219 ARPLTRYLPIRKE 1231
+ L L + +E
Sbjct: 2591 NQRLREQLQLLEE 2603
Score = 68.2 bits (165), Expect = 5e-11
Identities = 156/694 (22%), Positives = 276/694 (39%), Gaps = 96/694 (13%)
Query: 596 QRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSR 655
Q+Q+R ++E+++L RQ E + A + A E L I E + L R
Sbjct: 1412 QQQKRSIQEELQQL-RQSSEAEIQAKARQAEA---AERSRL-RIEEEIRVVRLQLEATER 1466
Query: 656 GLAGASG-----RSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQ 710
GA G R+ E A +R ++ E ++ + + S Q E E A K +
Sbjct: 1467 QRGGAEGELQALRARAEEAEAQKR--QAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1524
Query: 711 GEVLALEEERAQVLGHVEQLKVRVKELEQQLQESA--REAEMERALLQGEREAERALLQK 768
E A E++RA L +E+L+++ +E E++L+++ R +++ AL +R AE L K
Sbjct: 1525 AEA-AREKQRA--LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSK 1581
Query: 769 EQKAVDQ-------LQEKLVA---LETGIQKERDKEAEALETETKLFEDLEFQQLERES- 817
++ LQE+ VA L ++ ++AEA + +LE QL+
Sbjct: 1582 RASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEA 1641
Query: 818 ---RVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKN 874
R++ E + L +++AE + A+R+ R + G+ QAV++ E ++
Sbjct: 1642 LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREAR------RRGKAEEQAVRQRELAEQELE 1695
Query: 875 ASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTL--KEMEKLLLPAVDLEQWYQELMA 932
QL + ++ E+ L + L +E+ +L A Q QEL A
Sbjct: 1696 KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1755
Query: 933 GLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRT---RSGPLPSSSGSSS 989
L A + + SR +SK EA + R + L + + +
Sbjct: 1756 ELAKVRAEMEVLLASKARAEEESRSTSE-KSKQRLEAEAGRFRELAEEAARLRALAEEAK 1814
Query: 990 SSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEE-- 1047
QL+ R + +L + T +I K + A ++ +++ E+
Sbjct: 1815 RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1874
Query: 1048 -QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGE 1106
QRRRL E + A+ + + L A+ ++ R + EE
Sbjct: 1875 FQRRRLEEQAAQHKADIEERLAQLRKASDSELE-------RQKGLVEDTLRQRRQVEE-- 1925
Query: 1107 HAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIE-EMEKMLKEAHAEKN-R 1164
+ L+L++S + GK E E+E ++AE R
Sbjct: 1926 ---EILALKASFEKAAA----------------------GKAELELELGRIRSNAEDTLR 1960
Query: 1165 LMESREREMELRRQALEEERRRREQVERRLQ------SESARRQQLVEKEVKMREKQFSQ 1218
E E E +RQ EE RRR + E R+Q E+AR+++ +EV+ + + +
Sbjct: 1961 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2020
Query: 1219 ARPL--------TRYLPIRKEDFDLKTHIESSGH 1244
AR L R L + +E + E H
Sbjct: 2021 ARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH 2054
Score = 61.6 bits (148), Expect = 5e-09
Identities = 165/730 (22%), Positives = 285/730 (39%), Gaps = 129/730 (17%)
Query: 584 DNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEAT 643
+ E+ L E R + +ERL E E LE+QR L ++A EA EL +
Sbjct: 1345 EEEERLAEQQRAEERERLAEVEAA-LEKQRQ---LAEAHAQAKAQAEREAKEL----QQR 1396
Query: 644 AALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHED 703
+ R + A RS +E Q+L +S E + ++ ++ S + E+
Sbjct: 1397 MQEEVVRREEAAVDAQQQKRSIQEE---LQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1453
Query: 704 APSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGERE--- 760
+LQ E A E +R G ++ L+ R +E E Q +++ EAE R +Q E +
Sbjct: 1454 IRVVRLQLE--ATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKR 1511
Query: 761 -----------AERALLQKEQKAVDQLQEKLVALETGIQKERDKEAE-------ALETET 802
AE +++Q+A+ L+E + E ++ R E E ALET
Sbjct: 1512 QAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ 1571
Query: 803 KLFEDLEFQ-----------QLERE--------SRVEEERELAGQGLLRSKAELLRSIAK 843
+ E E Q QLER +++ EE E Q +++AE R A+
Sbjct: 1572 RSAE-AELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQ--QQAEAERAREEAE 1628
Query: 844 RK-ERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERR--------- 893
R+ ER + ++A ++R QA E +A+ K+ + +K+KE+ RR
Sbjct: 1629 RELERWQLKANEALRLRLQA----EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1684
Query: 894 ------YHSLTGGRPFPKTTS--TLKEMEKLLLPAVDLEQWYQ------ELMAGLGTGPA 939
L R + T+ L ++L+ + EQ Q E +A L A
Sbjct: 1685 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1744
Query: 940 AASPHSSPPPLP-AKASRQLQVY-----RSKMDGEATSPLPRTR--------------SG 979
AA+ AK +++V R++ + +TS + R +
Sbjct: 1745 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1804
Query: 980 PLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQ 1039
L + + + QL+ R + +L + T +I K + A +
Sbjct: 1805 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1864
Query: 1040 KGQQVIEE---QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLP 1096
+ +++ E+ QRRRL E + A+ + + L A+ L L
Sbjct: 1865 RLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASD--------SELERQKGLVEDT 1916
Query: 1097 AGRERGEEGEHAYDTLSLE--SSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKM 1154
+ R E E S E ++ E + G + + D + S ++ + +
Sbjct: 1917 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1976
Query: 1155 LKEAHAEK---NRLMESREREMELRRQ---ALEEERRRREQVE------RRLQSESARRQ 1202
+E + R+ +S E E RQ ALEE R + +VE R + ESAR+
Sbjct: 1977 AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQL 2036
Query: 1203 QLVEKEVKMR 1212
QL ++ + R
Sbjct: 2037 QLAQEAAQKR 2046
Score = 57.0 bits (136), Expect = 1e-07
Identities = 109/483 (22%), Positives = 190/483 (39%), Gaps = 82/483 (16%)
Query: 554 QSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQR 613
Q V+++L++ L++ T +KN + E RQR + E R++ +
Sbjct: 2180 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEE 2239
Query: 614 LETILNLCAEYSRA------DGGP-----EAGELPSIGEATAALALAGRRPSRGLAGASG 662
L + +RA D EA ++ + E A L++A + +R A
Sbjct: 2240 LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEE 2299
Query: 663 RSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQ 722
+++ +A + L E M+ E + + Q+E + +LQ + +E+ AQ
Sbjct: 2300 DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED----KEQMAQ 2355
Query: 723 VLGHVEQLKVRVKELEQQ--LQESA-------REAEMERALLQGEREAERALLQKEQKAV 773
L Q R E E+Q L+ SA R AEM RA + E +A+R +K
Sbjct: 2356 QLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRF-----RKQA 2410
Query: 774 DQLQEKLVALETGIQK---------------------------ERDKEAEALETETKLFE 806
+++ EKL E Q+ E ++E E L+ E KL +
Sbjct: 2411 EEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2470
Query: 807 --DLEFQQLERESRVEEERELAGQGLLRSKAELL---RSIAKRKERLAILDSQAGQIRAQ 861
E Q +++E ++E + L Q L K LL R I + K +L Q+
Sbjct: 2471 LKSEEMQTVQQEQLLQETQALQ-QSFLSEKDSLLQRERFIEQEKAKLE-------QLFQD 2522
Query: 862 AVQESERLARDKNASLQLLQKEKEKLTV----LERRYHSLTGG-----RPFPKTTSTLKE 912
V ++++L ++ Q +++E+++L RR H G + ++
Sbjct: 2523 EVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2582
Query: 913 MEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSP-PPLPAKASRQLQVYRSKMDGEATS 971
E+LL + Q +E + L AA HS A++ L R +DG A
Sbjct: 2583 QEELL---AEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAE 2639
Query: 972 PLP 974
P
Sbjct: 2640 AEP 2642
Score = 56.6 bits (135), Expect = 2e-07
Identities = 140/678 (20%), Positives = 259/678 (38%), Gaps = 97/678 (14%)
Query: 574 ERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEA 633
ER + + SD+E +RQ+ L E + R RQ E IL L A + +A G
Sbjct: 1893 ERLAQLRKASDSE--------LERQKGLVEDTL-RQRRQVEEEILALKASFEKAAAGKAE 1943
Query: 634 GELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSS 693
EL GR S + E A QR + E
Sbjct: 1944 LELE-----------LGRIRSNAEDTLRSKEQAELEAARQRQLAAEE------------- 1979
Query: 694 TESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERA 753
E ++E E+ L E A + +A L VE+LK +V+E ++L+E A
Sbjct: 1980 -ERRRREAEERVQKSLAAEEEAARQRKA-ALEEVERLKAKVEEA-RRLRERA-------- 2028
Query: 754 LLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQ-- 811
E+E+ R L ++ A +LQ + A +Q++ + + L+ E + + L +
Sbjct: 2029 ----EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2084
Query: 812 ------QLERESRVEEERELAGQGLLRSKAELLRSIAKRK-ERLAILDSQAGQIRAQAVQ 864
+ E+RV+ ERE A +AE L+ A+ + + A + A ++R +A Q
Sbjct: 2085 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ 2144
Query: 865 ESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVD-- 922
E+ R A+ + A+L+ +++ E H + + +E+ L L +
Sbjct: 2145 EAARRAQAEQAALR-----QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETD 2199
Query: 923 -----LEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTR 977
L++ Q L A S +L +++++ E + + R +
Sbjct: 2200 HQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDK 2259
Query: 978 SGPLPSSSGSSSSSSQLSVATLGRSPSPKSA----------LLTQNGTGS--LPRNLAAT 1025
+ Q++ S + + A L Q L + A
Sbjct: 2260 DNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAV 2319
Query: 1026 LQDIETKRQLALQQKGQQVIEEQRRRLAE----LKQKAAAEAQCQWDALHGAAPFPAGPS 1081
+ K + L Q+ +++ +EQ RRL E + Q+ A E Q L S
Sbjct: 2320 QEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2379
Query: 1082 GFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSAS 1141
+ + + + R EE + + E + + + + + ++
Sbjct: 2380 AEAERLKLRVA-EMSRAQARAEEDAQRFRKQAEEIGEKLHRT------ELATQEKVTLVQ 2432
Query: 1142 GLDMGK--IEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESA 1199
L++ + + + L+EA AE R E ++E +L + L+ E + Q E+ LQ A
Sbjct: 2433 TLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ--LKSEEMQTVQQEQLLQETQA 2490
Query: 1200 RRQQ-LVEKEVKMREKQF 1216
+Q L EK+ ++ ++F
Sbjct: 2491 LQQSFLSEKDSLLQRERF 2508
Score = 56.2 bits (134), Expect = 2e-07
Identities = 155/719 (21%), Positives = 275/719 (38%), Gaps = 122/719 (16%)
Query: 576 KNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGE 635
K + E S E+ + R+ ER +Q+ E ER R E L +A+ EA
Sbjct: 1588 KTAQLERSLQEEHVAVAQLREEAERRAQQQAEA-ERAREEAERELERWQLKAN---EALR 1643
Query: 636 LPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTE 695
L E A + + + R + G A ++ E +++E L+++ E
Sbjct: 1644 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE-LEKQRQLAE 1702
Query: 696 STQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREA------- 748
T Q+ LA E+E ++ EQ + + + LE++L REA
Sbjct: 1703 GTAQQR------------LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR 1750
Query: 749 ---EMERALLQGERE---AERALLQKEQKAVDQLQEKLVALETGIQKERDKEA---EALE 799
E E A ++ E E A +A ++E ++ + ++ + E G +E +EA AL
Sbjct: 1751 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1810
Query: 800 TETK-----LFEDLEFQQLERESRVEEERELAGQGL-LRSKAEL-LRSIAKRKERLAILD 852
E K ED Q+ E E + E+ G+ L+++AE+ L+ ERL L
Sbjct: 1811 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA 1870
Query: 853 S----QAGQIRAQAVQE----SERLARDKNASLQLLQKEKEKL--TVLERRYHSLTGGRP 902
Q ++ QA Q ERLA+ + AS L+++K + T+ +RR
Sbjct: 1871 EDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR--------- 1921
Query: 903 FPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYR 962
+ E++L E+ AAA L S R
Sbjct: 1922 --------QVEEEILALKASFEK-------------AAAGKAELELELGRIRSNAEDTLR 1960
Query: 963 SKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNL 1022
SK E + R + + Q S+A + + A L + L
Sbjct: 1961 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE------VERL 2014
Query: 1023 AATLQDIETKRQLALQQKGQQV----IEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPA 1078
A +++ R+ A Q+ +Q+ Q+R AE K A A Q + +
Sbjct: 2015 KAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQ---- 2070
Query: 1079 GPSGFPPLMHHSILHHL----PAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSP 1134
S+L L A R EE E A E++ S + S
Sbjct: 2071 --------QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS-RRQVEEAERLKQSA 2121
Query: 1135 DNMSSASGLDMGKIEEMEK-----MLKEAHAEKNRLMESR--EREMELRRQALEEERRRR 1187
+ + A E++ K + A AE+ L + + + EME ++ E+ R++
Sbjct: 2122 EEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2181
Query: 1188 EQVERRLQS------ESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIE 1240
QVE+ L + E+ ++ L+++E++ + + ++A + + +E F ++ +E
Sbjct: 2182 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA--ARQRSQVEEELFSVRVQME 2238
Score = 50.1 bits (118), Expect = 1e-05
Identities = 115/550 (20%), Positives = 214/550 (38%), Gaps = 75/550 (13%)
Query: 695 ESTQQEH--EDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMER 752
E QQ H D + + V L E VL + + +++L +QL+ A+
Sbjct: 1161 ERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLG 1220
Query: 753 ALLQGEREAERAL----LQKEQKAVDQLQEKLVALETGIQKERDKEAEA---LETETKLF 805
A LQ R + + L Q +QL+++ LE I++ +K E +
Sbjct: 1221 AWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEE-IERHGEKVEECQRFAKQYINAI 1279
Query: 806 EDLEFQQLERESRVEEERELAGQGLLRSKAELLRS----IAKRKERLAILDSQAGQIRAQ 861
+D E Q + ++++E A + ++S +E + + L L SQ + ++
Sbjct: 1280 KDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISE 1339
Query: 862 AV---QESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLL 918
+ +E ERLA + A +E+E+L +E +L R + + K +
Sbjct: 1340 TLRRMEEEERLAEQQRA------EERERLAEVEA---ALEKQRQLAEAHAQAKAQAER-- 1388
Query: 919 PAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRS 978
A +L+Q QE + A +LQ R + E + + +
Sbjct: 1389 EAKELQQRMQEEVVRREEAAVDAQQQKR------SIQEELQQLRQSSEAEIQAKARQAEA 1442
Query: 979 GPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQ 1038
+ ++ V L + + + G + L A ++ E +++ A +
Sbjct: 1443 ----AERSRLRIEEEIRVVRLQLEATERQ----RGGAEGELQALRARAEEAEAQKRQAQE 1494
Query: 1039 Q----KGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHH 1094
+ + Q E QR+R AE++ + +A+ + A L
Sbjct: 1495 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA-----------------LQA 1537
Query: 1095 LPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKM 1154
L R + EE E +E + ++ ++ T SA + AS + K ++E+
Sbjct: 1538 LEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE--KTAQLERS 1595
Query: 1155 LKEAHAEKNRLMESREREMELRRQALEEERRRREQVER-----RLQSESARRQQLVEKEV 1209
L+E H +L E ER R Q E R RE+ ER +L++ A R +L +EV
Sbjct: 1596 LQEEHVAVAQLREEAER----RAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1651
Query: 1210 KMREKQFSQA 1219
++K +QA
Sbjct: 1652 -AQQKSLAQA 1660
Score = 35.8 bits (81), Expect = 0.29
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVE 1206
++EE E++ ++ AE+ + E +E +RQ E + + Q ER E+ QQ ++
Sbjct: 1343 RMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAER----EAKELQQRMQ 1398
Query: 1207 KEVKMREKQFSQARPLTR 1224
+EV RE+ A+ R
Sbjct: 1399 EEVVRREEAAVDAQQQKR 1416
>gi|41322914 plectin 1 isoform 10 [Homo sapiens]
Length = 4551
Score = 73.2 bits (178), Expect = 2e-12
Identities = 142/692 (20%), Positives = 275/692 (39%), Gaps = 80/692 (11%)
Query: 566 DLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYS 625
+L + + R R N+ + E LE RQRQ E+ R +R++ L E +
Sbjct: 1947 ELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAEERVQKSLAAEEEAA 2005
Query: 626 RADGGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEE 685
R L + A + A R R S R + A Q+ ++ E++
Sbjct: 2006 RQ----RKAALEEVERLKAKVEEARRLRERA-EQESARQLQLAQEAAQKRLQAEEKAHAF 2060
Query: 686 NLKEECSSTESTQQEHEDAPSTKLQGEVLAL-------EEERAQVLGHVEQLKVRVKELE 738
++++ + T Q+ E + +L+GE A EE R Q Q + +V+E E
Sbjct: 2061 AVQQKEQELQQTLQQ-EQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE 2119
Query: 739 QQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVAL------ETGIQKERD 792
+ L++SA E RA Q + AE+ + EQ+A + Q + AL + ++K +
Sbjct: 2120 R-LKQSAEEQAQARA--QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2176
Query: 793 KEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKE------ 846
+ L + ++ ++L +L+ E + ++ L + L R KAE + +R +
Sbjct: 2177 FAEQTLRQKAQVEQELTTLRLQLE-ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELF 2235
Query: 847 RLAILDSQAGQIRAQAVQESERL-ARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPK 905
+ + + +++A+ E+ L RDK+ + + LQ+E EK+ + L+
Sbjct: 2236 SVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAA 2295
Query: 906 TTSTLKEMEKLLLPAVDLEQWYQELMAGLGTG---PAAASPHSSPPPLPAKASRQLQVYR 962
L E E L E+ +E M + A A L + +R+LQ +
Sbjct: 2296 RLRQLAE-EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK 2354
Query: 963 SKMD---GEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLP 1019
+M E T RT S+ + +L + S + A
Sbjct: 2355 EQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA----EEDAQRF 2410
Query: 1020 RNLAATLQDIETKRQLALQQKGQ--QVIEEQRRRL---AELKQKAAAEAQCQWDALHGAA 1074
R A + + + +LA Q+K Q +E QR++ AE ++A AE + + + L A
Sbjct: 2411 RKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEA 2470
Query: 1075 PFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSP 1134
+ + EE + L+ + +++ S + +S
Sbjct: 2471 KLL---------------------QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2509
Query: 1135 DNMSSASGLDMGKI------------EEMEKMLKEAHAEKNRLMESREREMELRRQALEE 1182
+ + ++ EE ++ ++ E+ RL+ S E + +A E
Sbjct: 2510 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2569
Query: 1183 ERRRREQVERRLQSESARRQQLVEKEVKMREK 1214
RR++E++++ Q + + L E+ ++RE+
Sbjct: 2570 VRRKQEELQQLEQQRRQQEELLAEENQRLREQ 2601
Score = 72.0 bits (175), Expect = 4e-12
Identities = 144/673 (21%), Positives = 276/673 (41%), Gaps = 81/673 (12%)
Query: 591 EYHRRQRQERLR-----EQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAA 645
E RR+ +ER++ E+E R + LE + L A+ A E E S + A
Sbjct: 1984 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLA 2043
Query: 646 LALAGRR-PSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDA 704
A +R + A A +E Q L +++++ ++ L + E+ ++ E+A
Sbjct: 2044 QEAAQKRLQAEEKAHAFAVQQKE-----QELQQTLQQ-EQSVLDQLRGEAEAARRAAEEA 2097
Query: 705 PSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAR-EAEMERALLQGEREAER 763
++Q E E AQ VE+ + + E+Q Q A+ +A E+ + E+EA R
Sbjct: 2098 EEARVQAE-----REAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2152
Query: 764 ALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEER 823
Q EQ A+ Q Q A + ++K + + L + ++ ++L +L+ E + ++
Sbjct: 2153 RA-QAEQAALRQKQ----AADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE-TDHQK 2206
Query: 824 ELAGQGLLRSKAELLRSIAKRKE------RLAILDSQAGQIRAQAVQESERLA-RDKNAS 876
L + L R KAE + +R + + + + +++A+ E+ L RDK+ +
Sbjct: 2207 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2266
Query: 877 LQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGT 936
+ LQ+E EK+ + L+ L E E L E+ +E M +
Sbjct: 2267 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAE-EDLAQQRALAEKMLKEKMQAVQE 2325
Query: 937 GP---AAASPHSSPPPLPAKASRQLQVYRSKMD---GEATSPLPRTRSGPLPSSSGSSSS 990
A A L + +R+LQ + +M E T RT S+
Sbjct: 2326 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2385
Query: 991 SSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQ--QVIEEQ 1048
+ +L + S + A R A + + + +LA Q+K Q +E Q
Sbjct: 2386 AERLKLRVAEMSRAQARA----EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ 2441
Query: 1049 RRRL---AELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEG 1105
R++ AE ++A AE + + + L A + + EE
Sbjct: 2442 RQQSDHDAERLREAIAELEREKEKLQQEAKLL---------------------QLKSEEM 2480
Query: 1106 EHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRL 1165
+ L+ + +++ S + +S + ++ K + +E++ ++ A+ +L
Sbjct: 2481 QTVQQEQLLQETQALQQSFLSEKDSLLQRERF-----IEQEKAK-LEQLFQDEVAKAQQL 2534
Query: 1166 MESRERE---MELRRQAL----EEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQ 1218
E ++R+ ME RQ L EE RRR+ + E ++ + QQL ++ + E +
Sbjct: 2535 REEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEE 2594
Query: 1219 ARPLTRYLPIRKE 1231
+ L L + +E
Sbjct: 2595 NQRLREQLQLLEE 2607
Score = 68.2 bits (165), Expect = 5e-11
Identities = 156/694 (22%), Positives = 276/694 (39%), Gaps = 96/694 (13%)
Query: 596 QRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSR 655
Q+Q+R ++E+++L RQ E + A + A E L I E + L R
Sbjct: 1416 QQQKRSIQEELQQL-RQSSEAEIQAKARQAEA---AERSRL-RIEEEIRVVRLQLEATER 1470
Query: 656 GLAGASG-----RSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQ 710
GA G R+ E A +R ++ E ++ + + S Q E E A K +
Sbjct: 1471 QRGGAEGELQALRARAEEAEAQKR--QAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1528
Query: 711 GEVLALEEERAQVLGHVEQLKVRVKELEQQLQESA--REAEMERALLQGEREAERALLQK 768
E A E++RA L +E+L+++ +E E++L+++ R +++ AL +R AE L K
Sbjct: 1529 AEA-AREKQRA--LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSK 1585
Query: 769 EQKAVDQ-------LQEKLVA---LETGIQKERDKEAEALETETKLFEDLEFQQLERES- 817
++ LQE+ VA L ++ ++AEA + +LE QL+
Sbjct: 1586 RASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEA 1645
Query: 818 ---RVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKN 874
R++ E + L +++AE + A+R+ R + G+ QAV++ E ++
Sbjct: 1646 LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREAR------RRGKAEEQAVRQRELAEQELE 1699
Query: 875 ASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTL--KEMEKLLLPAVDLEQWYQELMA 932
QL + ++ E+ L + L +E+ +L A Q QEL A
Sbjct: 1700 KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1759
Query: 933 GLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRT---RSGPLPSSSGSSS 989
L A + + SR +SK EA + R + L + + +
Sbjct: 1760 ELAKVRAEMEVLLASKARAEEESRSTSE-KSKQRLEAEAGRFRELAEEAARLRALAEEAK 1818
Query: 990 SSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEE-- 1047
QL+ R + +L + T +I K + A ++ +++ E+
Sbjct: 1819 RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1878
Query: 1048 -QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGE 1106
QRRRL E + A+ + + L A+ ++ R + EE
Sbjct: 1879 FQRRRLEEQAAQHKADIEERLAQLRKASDSELE-------RQKGLVEDTLRQRRQVEE-- 1929
Query: 1107 HAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIE-EMEKMLKEAHAEKN-R 1164
+ L+L++S + GK E E+E ++AE R
Sbjct: 1930 ---EILALKASFEKAAA----------------------GKAELELELGRIRSNAEDTLR 1964
Query: 1165 LMESREREMELRRQALEEERRRREQVERRLQ------SESARRQQLVEKEVKMREKQFSQ 1218
E E E +RQ EE RRR + E R+Q E+AR+++ +EV+ + + +
Sbjct: 1965 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2024
Query: 1219 ARPL--------TRYLPIRKEDFDLKTHIESSGH 1244
AR L R L + +E + E H
Sbjct: 2025 ARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH 2058
Score = 61.6 bits (148), Expect = 5e-09
Identities = 165/730 (22%), Positives = 285/730 (39%), Gaps = 129/730 (17%)
Query: 584 DNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEAT 643
+ E+ L E R + +ERL E E LE+QR L ++A EA EL +
Sbjct: 1349 EEEERLAEQQRAEERERLAEVEAA-LEKQRQ---LAEAHAQAKAQAEREAKEL----QQR 1400
Query: 644 AALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHED 703
+ R + A RS +E Q+L +S E + ++ ++ S + E+
Sbjct: 1401 MQEEVVRREEAAVDAQQQKRSIQEE---LQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1457
Query: 704 APSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGERE--- 760
+LQ E A E +R G ++ L+ R +E E Q +++ EAE R +Q E +
Sbjct: 1458 IRVVRLQLE--ATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKR 1515
Query: 761 -----------AERALLQKEQKAVDQLQEKLVALETGIQKERDKEAE-------ALETET 802
AE +++Q+A+ L+E + E ++ R E E ALET
Sbjct: 1516 QAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ 1575
Query: 803 KLFEDLEFQ-----------QLERE--------SRVEEERELAGQGLLRSKAELLRSIAK 843
+ E E Q QLER +++ EE E Q +++AE R A+
Sbjct: 1576 RSAE-AELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQ--QQAEAERAREEAE 1632
Query: 844 RK-ERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERR--------- 893
R+ ER + ++A ++R QA E +A+ K+ + +K+KE+ RR
Sbjct: 1633 RELERWQLKANEALRLRLQA----EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1688
Query: 894 ------YHSLTGGRPFPKTTS--TLKEMEKLLLPAVDLEQWYQ------ELMAGLGTGPA 939
L R + T+ L ++L+ + EQ Q E +A L A
Sbjct: 1689 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1748
Query: 940 AASPHSSPPPLP-AKASRQLQVY-----RSKMDGEATSPLPRTR--------------SG 979
AA+ AK +++V R++ + +TS + R +
Sbjct: 1749 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1808
Query: 980 PLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQ 1039
L + + + QL+ R + +L + T +I K + A +
Sbjct: 1809 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1868
Query: 1040 KGQQVIEE---QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLP 1096
+ +++ E+ QRRRL E + A+ + + L A+ L L
Sbjct: 1869 RLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASD--------SELERQKGLVEDT 1920
Query: 1097 AGRERGEEGEHAYDTLSLE--SSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKM 1154
+ R E E S E ++ E + G + + D + S ++ + +
Sbjct: 1921 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1980
Query: 1155 LKEAHAEK---NRLMESREREMELRRQ---ALEEERRRREQVE------RRLQSESARRQ 1202
+E + R+ +S E E RQ ALEE R + +VE R + ESAR+
Sbjct: 1981 AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQL 2040
Query: 1203 QLVEKEVKMR 1212
QL ++ + R
Sbjct: 2041 QLAQEAAQKR 2050
Score = 57.0 bits (136), Expect = 1e-07
Identities = 109/483 (22%), Positives = 190/483 (39%), Gaps = 82/483 (16%)
Query: 554 QSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQR 613
Q V+++L++ L++ T +KN + E RQR + E R++ +
Sbjct: 2184 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEE 2243
Query: 614 LETILNLCAEYSRA------DGGP-----EAGELPSIGEATAALALAGRRPSRGLAGASG 662
L + +RA D EA ++ + E A L++A + +R A
Sbjct: 2244 LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEE 2303
Query: 663 RSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQ 722
+++ +A + L E M+ E + + Q+E + +LQ + +E+ AQ
Sbjct: 2304 DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED----KEQMAQ 2359
Query: 723 VLGHVEQLKVRVKELEQQ--LQESA-------REAEMERALLQGEREAERALLQKEQKAV 773
L Q R E E+Q L+ SA R AEM RA + E +A+R +K
Sbjct: 2360 QLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRF-----RKQA 2414
Query: 774 DQLQEKLVALETGIQK---------------------------ERDKEAEALETETKLFE 806
+++ EKL E Q+ E ++E E L+ E KL +
Sbjct: 2415 EEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2474
Query: 807 --DLEFQQLERESRVEEERELAGQGLLRSKAELL---RSIAKRKERLAILDSQAGQIRAQ 861
E Q +++E ++E + L Q L K LL R I + K +L Q+
Sbjct: 2475 LKSEEMQTVQQEQLLQETQALQ-QSFLSEKDSLLQRERFIEQEKAKLE-------QLFQD 2526
Query: 862 AVQESERLARDKNASLQLLQKEKEKLTV----LERRYHSLTGG-----RPFPKTTSTLKE 912
V ++++L ++ Q +++E+++L RR H G + ++
Sbjct: 2527 EVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2586
Query: 913 MEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSP-PPLPAKASRQLQVYRSKMDGEATS 971
E+LL + Q +E + L AA HS A++ L R +DG A
Sbjct: 2587 QEELL---AEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAE 2643
Query: 972 PLP 974
P
Sbjct: 2644 AEP 2646
Score = 56.6 bits (135), Expect = 2e-07
Identities = 140/678 (20%), Positives = 259/678 (38%), Gaps = 97/678 (14%)
Query: 574 ERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEA 633
ER + + SD+E +RQ+ L E + R RQ E IL L A + +A G
Sbjct: 1897 ERLAQLRKASDSE--------LERQKGLVEDTL-RQRRQVEEEILALKASFEKAAAGKAE 1947
Query: 634 GELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSS 693
EL GR S + E A QR + E
Sbjct: 1948 LELE-----------LGRIRSNAEDTLRSKEQAELEAARQRQLAAEE------------- 1983
Query: 694 TESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERA 753
E ++E E+ L E A + +A L VE+LK +V+E ++L+E A
Sbjct: 1984 -ERRRREAEERVQKSLAAEEEAARQRKA-ALEEVERLKAKVEEA-RRLRERA-------- 2032
Query: 754 LLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQ-- 811
E+E+ R L ++ A +LQ + A +Q++ + + L+ E + + L +
Sbjct: 2033 ----EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2088
Query: 812 ------QLERESRVEEERELAGQGLLRSKAELLRSIAKRK-ERLAILDSQAGQIRAQAVQ 864
+ E+RV+ ERE A +AE L+ A+ + + A + A ++R +A Q
Sbjct: 2089 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ 2148
Query: 865 ESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVD-- 922
E+ R A+ + A+L+ +++ E H + + +E+ L L +
Sbjct: 2149 EAARRAQAEQAALR-----QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETD 2203
Query: 923 -----LEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTR 977
L++ Q L A S +L +++++ E + + R +
Sbjct: 2204 HQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDK 2263
Query: 978 SGPLPSSSGSSSSSSQLSVATLGRSPSPKSA----------LLTQNGTGS--LPRNLAAT 1025
+ Q++ S + + A L Q L + A
Sbjct: 2264 DNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAV 2323
Query: 1026 LQDIETKRQLALQQKGQQVIEEQRRRLAE----LKQKAAAEAQCQWDALHGAAPFPAGPS 1081
+ K + L Q+ +++ +EQ RRL E + Q+ A E Q L S
Sbjct: 2324 QEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2383
Query: 1082 GFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSAS 1141
+ + + + R EE + + E + + + + + ++
Sbjct: 2384 AEAERLKLRVA-EMSRAQARAEEDAQRFRKQAEEIGEKLHRT------ELATQEKVTLVQ 2436
Query: 1142 GLDMGK--IEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESA 1199
L++ + + + L+EA AE R E ++E +L + L+ E + Q E+ LQ A
Sbjct: 2437 TLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ--LKSEEMQTVQQEQLLQETQA 2494
Query: 1200 RRQQ-LVEKEVKMREKQF 1216
+Q L EK+ ++ ++F
Sbjct: 2495 LQQSFLSEKDSLLQRERF 2512
Score = 56.2 bits (134), Expect = 2e-07
Identities = 155/719 (21%), Positives = 275/719 (38%), Gaps = 122/719 (16%)
Query: 576 KNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGE 635
K + E S E+ + R+ ER +Q+ E ER R E L +A+ EA
Sbjct: 1592 KTAQLERSLQEEHVAVAQLREEAERRAQQQAEA-ERAREEAERELERWQLKAN---EALR 1647
Query: 636 LPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTE 695
L E A + + + R + G A ++ E +++E L+++ E
Sbjct: 1648 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE-LEKQRQLAE 1706
Query: 696 STQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREA------- 748
T Q+ LA E+E ++ EQ + + + LE++L REA
Sbjct: 1707 GTAQQR------------LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR 1754
Query: 749 ---EMERALLQGERE---AERALLQKEQKAVDQLQEKLVALETGIQKERDKEA---EALE 799
E E A ++ E E A +A ++E ++ + ++ + E G +E +EA AL
Sbjct: 1755 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1814
Query: 800 TETK-----LFEDLEFQQLERESRVEEERELAGQGL-LRSKAEL-LRSIAKRKERLAILD 852
E K ED Q+ E E + E+ G+ L+++AE+ L+ ERL L
Sbjct: 1815 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA 1874
Query: 853 S----QAGQIRAQAVQE----SERLARDKNASLQLLQKEKEKL--TVLERRYHSLTGGRP 902
Q ++ QA Q ERLA+ + AS L+++K + T+ +RR
Sbjct: 1875 EDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR--------- 1925
Query: 903 FPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYR 962
+ E++L E+ AAA L S R
Sbjct: 1926 --------QVEEEILALKASFEK-------------AAAGKAELELELGRIRSNAEDTLR 1964
Query: 963 SKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNL 1022
SK E + R + + Q S+A + + A L + L
Sbjct: 1965 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE------VERL 2018
Query: 1023 AATLQDIETKRQLALQQKGQQV----IEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPA 1078
A +++ R+ A Q+ +Q+ Q+R AE K A A Q + +
Sbjct: 2019 KAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQ---- 2074
Query: 1079 GPSGFPPLMHHSILHHL----PAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSP 1134
S+L L A R EE E A E++ S + S
Sbjct: 2075 --------QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS-RRQVEEAERLKQSA 2125
Query: 1135 DNMSSASGLDMGKIEEMEK-----MLKEAHAEKNRLMESR--EREMELRRQALEEERRRR 1187
+ + A E++ K + A AE+ L + + + EME ++ E+ R++
Sbjct: 2126 EEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2185
Query: 1188 EQVERRLQS------ESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIE 1240
QVE+ L + E+ ++ L+++E++ + + ++A + + +E F ++ +E
Sbjct: 2186 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA--ARQRSQVEEELFSVRVQME 2242
Score = 50.1 bits (118), Expect = 1e-05
Identities = 115/550 (20%), Positives = 214/550 (38%), Gaps = 75/550 (13%)
Query: 695 ESTQQEH--EDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMER 752
E QQ H D + + V L E VL + + +++L +QL+ A+
Sbjct: 1165 ERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLG 1224
Query: 753 ALLQGEREAERAL----LQKEQKAVDQLQEKLVALETGIQKERDKEAEA---LETETKLF 805
A LQ R + + L Q +QL+++ LE I++ +K E +
Sbjct: 1225 AWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEE-IERHGEKVEECQRFAKQYINAI 1283
Query: 806 EDLEFQQLERESRVEEERELAGQGLLRSKAELLRS----IAKRKERLAILDSQAGQIRAQ 861
+D E Q + ++++E A + ++S +E + + L L SQ + ++
Sbjct: 1284 KDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISE 1343
Query: 862 AV---QESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLL 918
+ +E ERLA + A +E+E+L +E +L R + + K +
Sbjct: 1344 TLRRMEEEERLAEQQRA------EERERLAEVEA---ALEKQRQLAEAHAQAKAQAER-- 1392
Query: 919 PAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRS 978
A +L+Q QE + A +LQ R + E + + +
Sbjct: 1393 EAKELQQRMQEEVVRREEAAVDAQQQKR------SIQEELQQLRQSSEAEIQAKARQAEA 1446
Query: 979 GPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQ 1038
+ ++ V L + + + G + L A ++ E +++ A +
Sbjct: 1447 ----AERSRLRIEEEIRVVRLQLEATERQ----RGGAEGELQALRARAEEAEAQKRQAQE 1498
Query: 1039 Q----KGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHH 1094
+ + Q E QR+R AE++ + +A+ + A L
Sbjct: 1499 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA-----------------LQA 1541
Query: 1095 LPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKM 1154
L R + EE E +E + ++ ++ T SA + AS + K ++E+
Sbjct: 1542 LEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE--KTAQLERS 1599
Query: 1155 LKEAHAEKNRLMESREREMELRRQALEEERRRREQVER-----RLQSESARRQQLVEKEV 1209
L+E H +L E ER R Q E R RE+ ER +L++ A R +L +EV
Sbjct: 1600 LQEEHVAVAQLREEAER----RAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1655
Query: 1210 KMREKQFSQA 1219
++K +QA
Sbjct: 1656 -AQQKSLAQA 1664
Score = 35.8 bits (81), Expect = 0.29
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVE 1206
++EE E++ ++ AE+ + E +E +RQ E + + Q ER E+ QQ ++
Sbjct: 1347 RMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAER----EAKELQQRMQ 1402
Query: 1207 KEVKMREKQFSQARPLTR 1224
+EV RE+ A+ R
Sbjct: 1403 EEVVRREEAAVDAQQQKR 1420
>gi|41322919 plectin 1 isoform 8 [Homo sapiens]
Length = 4547
Score = 73.2 bits (178), Expect = 2e-12
Identities = 142/692 (20%), Positives = 275/692 (39%), Gaps = 80/692 (11%)
Query: 566 DLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYS 625
+L + + R R N+ + E LE RQRQ E+ R +R++ L E +
Sbjct: 1943 ELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAEERVQKSLAAEEEAA 2001
Query: 626 RADGGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEE 685
R L + A + A R R S R + A Q+ ++ E++
Sbjct: 2002 RQ----RKAALEEVERLKAKVEEARRLRERA-EQESARQLQLAQEAAQKRLQAEEKAHAF 2056
Query: 686 NLKEECSSTESTQQEHEDAPSTKLQGEVLAL-------EEERAQVLGHVEQLKVRVKELE 738
++++ + T Q+ E + +L+GE A EE R Q Q + +V+E E
Sbjct: 2057 AVQQKEQELQQTLQQ-EQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE 2115
Query: 739 QQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVAL------ETGIQKERD 792
+ L++SA E RA Q + AE+ + EQ+A + Q + AL + ++K +
Sbjct: 2116 R-LKQSAEEQAQARA--QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2172
Query: 793 KEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKE------ 846
+ L + ++ ++L +L+ E + ++ L + L R KAE + +R +
Sbjct: 2173 FAEQTLRQKAQVEQELTTLRLQLE-ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELF 2231
Query: 847 RLAILDSQAGQIRAQAVQESERL-ARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPK 905
+ + + +++A+ E+ L RDK+ + + LQ+E EK+ + L+
Sbjct: 2232 SVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAA 2291
Query: 906 TTSTLKEMEKLLLPAVDLEQWYQELMAGLGTG---PAAASPHSSPPPLPAKASRQLQVYR 962
L E E L E+ +E M + A A L + +R+LQ +
Sbjct: 2292 RLRQLAE-EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK 2350
Query: 963 SKMD---GEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLP 1019
+M E T RT S+ + +L + S + A
Sbjct: 2351 EQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA----EEDAQRF 2406
Query: 1020 RNLAATLQDIETKRQLALQQKGQ--QVIEEQRRRL---AELKQKAAAEAQCQWDALHGAA 1074
R A + + + +LA Q+K Q +E QR++ AE ++A AE + + + L A
Sbjct: 2407 RKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEA 2466
Query: 1075 PFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSP 1134
+ + EE + L+ + +++ S + +S
Sbjct: 2467 KLL---------------------QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2505
Query: 1135 DNMSSASGLDMGKI------------EEMEKMLKEAHAEKNRLMESREREMELRRQALEE 1182
+ + ++ EE ++ ++ E+ RL+ S E + +A E
Sbjct: 2506 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2565
Query: 1183 ERRRREQVERRLQSESARRQQLVEKEVKMREK 1214
RR++E++++ Q + + L E+ ++RE+
Sbjct: 2566 VRRKQEELQQLEQQRRQQEELLAEENQRLREQ 2597
Score = 72.0 bits (175), Expect = 4e-12
Identities = 144/673 (21%), Positives = 276/673 (41%), Gaps = 81/673 (12%)
Query: 591 EYHRRQRQERLR-----EQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAA 645
E RR+ +ER++ E+E R + LE + L A+ A E E S + A
Sbjct: 1980 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLA 2039
Query: 646 LALAGRR-PSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDA 704
A +R + A A +E Q L +++++ ++ L + E+ ++ E+A
Sbjct: 2040 QEAAQKRLQAEEKAHAFAVQQKE-----QELQQTLQQ-EQSVLDQLRGEAEAARRAAEEA 2093
Query: 705 PSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAR-EAEMERALLQGEREAER 763
++Q E E AQ VE+ + + E+Q Q A+ +A E+ + E+EA R
Sbjct: 2094 EEARVQAE-----REAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2148
Query: 764 ALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEER 823
Q EQ A+ Q Q A + ++K + + L + ++ ++L +L+ E + ++
Sbjct: 2149 RA-QAEQAALRQKQ----AADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE-TDHQK 2202
Query: 824 ELAGQGLLRSKAELLRSIAKRKE------RLAILDSQAGQIRAQAVQESERLA-RDKNAS 876
L + L R KAE + +R + + + + +++A+ E+ L RDK+ +
Sbjct: 2203 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2262
Query: 877 LQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGT 936
+ LQ+E EK+ + L+ L E E L E+ +E M +
Sbjct: 2263 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAE-EDLAQQRALAEKMLKEKMQAVQE 2321
Query: 937 GP---AAASPHSSPPPLPAKASRQLQVYRSKMD---GEATSPLPRTRSGPLPSSSGSSSS 990
A A L + +R+LQ + +M E T RT S+
Sbjct: 2322 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2381
Query: 991 SSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQ--QVIEEQ 1048
+ +L + S + A R A + + + +LA Q+K Q +E Q
Sbjct: 2382 AERLKLRVAEMSRAQARA----EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ 2437
Query: 1049 RRRL---AELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEG 1105
R++ AE ++A AE + + + L A + + EE
Sbjct: 2438 RQQSDHDAERLREAIAELEREKEKLQQEAKLL---------------------QLKSEEM 2476
Query: 1106 EHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRL 1165
+ L+ + +++ S + +S + ++ K + +E++ ++ A+ +L
Sbjct: 2477 QTVQQEQLLQETQALQQSFLSEKDSLLQRERF-----IEQEKAK-LEQLFQDEVAKAQQL 2530
Query: 1166 MESRERE---MELRRQAL----EEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQ 1218
E ++R+ ME RQ L EE RRR+ + E ++ + QQL ++ + E +
Sbjct: 2531 REEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEE 2590
Query: 1219 ARPLTRYLPIRKE 1231
+ L L + +E
Sbjct: 2591 NQRLREQLQLLEE 2603
Score = 68.2 bits (165), Expect = 5e-11
Identities = 156/694 (22%), Positives = 276/694 (39%), Gaps = 96/694 (13%)
Query: 596 QRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSR 655
Q+Q+R ++E+++L RQ E + A + A E L I E + L R
Sbjct: 1412 QQQKRSIQEELQQL-RQSSEAEIQAKARQAEA---AERSRL-RIEEEIRVVRLQLEATER 1466
Query: 656 GLAGASG-----RSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQ 710
GA G R+ E A +R ++ E ++ + + S Q E E A K +
Sbjct: 1467 QRGGAEGELQALRARAEEAEAQKR--QAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1524
Query: 711 GEVLALEEERAQVLGHVEQLKVRVKELEQQLQESA--REAEMERALLQGEREAERALLQK 768
E A E++RA L +E+L+++ +E E++L+++ R +++ AL +R AE L K
Sbjct: 1525 AEA-AREKQRA--LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSK 1581
Query: 769 EQKAVDQ-------LQEKLVA---LETGIQKERDKEAEALETETKLFEDLEFQQLERES- 817
++ LQE+ VA L ++ ++AEA + +LE QL+
Sbjct: 1582 RASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEA 1641
Query: 818 ---RVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKN 874
R++ E + L +++AE + A+R+ R + G+ QAV++ E ++
Sbjct: 1642 LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREAR------RRGKAEEQAVRQRELAEQELE 1695
Query: 875 ASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTL--KEMEKLLLPAVDLEQWYQELMA 932
QL + ++ E+ L + L +E+ +L A Q QEL A
Sbjct: 1696 KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1755
Query: 933 GLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRT---RSGPLPSSSGSSS 989
L A + + SR +SK EA + R + L + + +
Sbjct: 1756 ELAKVRAEMEVLLASKARAEEESRSTSE-KSKQRLEAEAGRFRELAEEAARLRALAEEAK 1814
Query: 990 SSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEE-- 1047
QL+ R + +L + T +I K + A ++ +++ E+
Sbjct: 1815 RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1874
Query: 1048 -QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGE 1106
QRRRL E + A+ + + L A+ ++ R + EE
Sbjct: 1875 FQRRRLEEQAAQHKADIEERLAQLRKASDSELE-------RQKGLVEDTLRQRRQVEE-- 1925
Query: 1107 HAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIE-EMEKMLKEAHAEKN-R 1164
+ L+L++S + GK E E+E ++AE R
Sbjct: 1926 ---EILALKASFEKAAA----------------------GKAELELELGRIRSNAEDTLR 1960
Query: 1165 LMESREREMELRRQALEEERRRREQVERRLQ------SESARRQQLVEKEVKMREKQFSQ 1218
E E E +RQ EE RRR + E R+Q E+AR+++ +EV+ + + +
Sbjct: 1961 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2020
Query: 1219 ARPL--------TRYLPIRKEDFDLKTHIESSGH 1244
AR L R L + +E + E H
Sbjct: 2021 ARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH 2054
Score = 61.6 bits (148), Expect = 5e-09
Identities = 165/730 (22%), Positives = 285/730 (39%), Gaps = 129/730 (17%)
Query: 584 DNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEAT 643
+ E+ L E R + +ERL E E LE+QR L ++A EA EL +
Sbjct: 1345 EEEERLAEQQRAEERERLAEVEAA-LEKQRQ---LAEAHAQAKAQAEREAKEL----QQR 1396
Query: 644 AALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHED 703
+ R + A RS +E Q+L +S E + ++ ++ S + E+
Sbjct: 1397 MQEEVVRREEAAVDAQQQKRSIQEE---LQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1453
Query: 704 APSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGERE--- 760
+LQ E A E +R G ++ L+ R +E E Q +++ EAE R +Q E +
Sbjct: 1454 IRVVRLQLE--ATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKR 1511
Query: 761 -----------AERALLQKEQKAVDQLQEKLVALETGIQKERDKEAE-------ALETET 802
AE +++Q+A+ L+E + E ++ R E E ALET
Sbjct: 1512 QAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ 1571
Query: 803 KLFEDLEFQ-----------QLERE--------SRVEEERELAGQGLLRSKAELLRSIAK 843
+ E E Q QLER +++ EE E Q +++AE R A+
Sbjct: 1572 RSAE-AELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQ--QQAEAERAREEAE 1628
Query: 844 RK-ERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERR--------- 893
R+ ER + ++A ++R QA E +A+ K+ + +K+KE+ RR
Sbjct: 1629 RELERWQLKANEALRLRLQA----EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1684
Query: 894 ------YHSLTGGRPFPKTTS--TLKEMEKLLLPAVDLEQWYQ------ELMAGLGTGPA 939
L R + T+ L ++L+ + EQ Q E +A L A
Sbjct: 1685 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1744
Query: 940 AASPHSSPPPLP-AKASRQLQVY-----RSKMDGEATSPLPRTR--------------SG 979
AA+ AK +++V R++ + +TS + R +
Sbjct: 1745 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1804
Query: 980 PLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQ 1039
L + + + QL+ R + +L + T +I K + A +
Sbjct: 1805 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1864
Query: 1040 KGQQVIEE---QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLP 1096
+ +++ E+ QRRRL E + A+ + + L A+ L L
Sbjct: 1865 RLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASD--------SELERQKGLVEDT 1916
Query: 1097 AGRERGEEGEHAYDTLSLE--SSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKM 1154
+ R E E S E ++ E + G + + D + S ++ + +
Sbjct: 1917 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1976
Query: 1155 LKEAHAEK---NRLMESREREMELRRQ---ALEEERRRREQVE------RRLQSESARRQ 1202
+E + R+ +S E E RQ ALEE R + +VE R + ESAR+
Sbjct: 1977 AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQL 2036
Query: 1203 QLVEKEVKMR 1212
QL ++ + R
Sbjct: 2037 QLAQEAAQKR 2046
Score = 57.0 bits (136), Expect = 1e-07
Identities = 109/483 (22%), Positives = 190/483 (39%), Gaps = 82/483 (16%)
Query: 554 QSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQR 613
Q V+++L++ L++ T +KN + E RQR + E R++ +
Sbjct: 2180 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEE 2239
Query: 614 LETILNLCAEYSRA------DGGP-----EAGELPSIGEATAALALAGRRPSRGLAGASG 662
L + +RA D EA ++ + E A L++A + +R A
Sbjct: 2240 LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEE 2299
Query: 663 RSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQ 722
+++ +A + L E M+ E + + Q+E + +LQ + +E+ AQ
Sbjct: 2300 DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED----KEQMAQ 2355
Query: 723 VLGHVEQLKVRVKELEQQ--LQESA-------REAEMERALLQGEREAERALLQKEQKAV 773
L Q R E E+Q L+ SA R AEM RA + E +A+R +K
Sbjct: 2356 QLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRF-----RKQA 2410
Query: 774 DQLQEKLVALETGIQK---------------------------ERDKEAEALETETKLFE 806
+++ EKL E Q+ E ++E E L+ E KL +
Sbjct: 2411 EEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2470
Query: 807 --DLEFQQLERESRVEEERELAGQGLLRSKAELL---RSIAKRKERLAILDSQAGQIRAQ 861
E Q +++E ++E + L Q L K LL R I + K +L Q+
Sbjct: 2471 LKSEEMQTVQQEQLLQETQALQ-QSFLSEKDSLLQRERFIEQEKAKLE-------QLFQD 2522
Query: 862 AVQESERLARDKNASLQLLQKEKEKLTV----LERRYHSLTGG-----RPFPKTTSTLKE 912
V ++++L ++ Q +++E+++L RR H G + ++
Sbjct: 2523 EVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2582
Query: 913 MEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSP-PPLPAKASRQLQVYRSKMDGEATS 971
E+LL + Q +E + L AA HS A++ L R +DG A
Sbjct: 2583 QEELL---AEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAE 2639
Query: 972 PLP 974
P
Sbjct: 2640 AEP 2642
Score = 56.6 bits (135), Expect = 2e-07
Identities = 140/678 (20%), Positives = 259/678 (38%), Gaps = 97/678 (14%)
Query: 574 ERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEA 633
ER + + SD+E +RQ+ L E + R RQ E IL L A + +A G
Sbjct: 1893 ERLAQLRKASDSE--------LERQKGLVEDTL-RQRRQVEEEILALKASFEKAAAGKAE 1943
Query: 634 GELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSS 693
EL GR S + E A QR + E
Sbjct: 1944 LELE-----------LGRIRSNAEDTLRSKEQAELEAARQRQLAAEE------------- 1979
Query: 694 TESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERA 753
E ++E E+ L E A + +A L VE+LK +V+E ++L+E A
Sbjct: 1980 -ERRRREAEERVQKSLAAEEEAARQRKA-ALEEVERLKAKVEEA-RRLRERA-------- 2028
Query: 754 LLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQ-- 811
E+E+ R L ++ A +LQ + A +Q++ + + L+ E + + L +
Sbjct: 2029 ----EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2084
Query: 812 ------QLERESRVEEERELAGQGLLRSKAELLRSIAKRK-ERLAILDSQAGQIRAQAVQ 864
+ E+RV+ ERE A +AE L+ A+ + + A + A ++R +A Q
Sbjct: 2085 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ 2144
Query: 865 ESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVD-- 922
E+ R A+ + A+L+ +++ E H + + +E+ L L +
Sbjct: 2145 EAARRAQAEQAALR-----QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETD 2199
Query: 923 -----LEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTR 977
L++ Q L A S +L +++++ E + + R +
Sbjct: 2200 HQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDK 2259
Query: 978 SGPLPSSSGSSSSSSQLSVATLGRSPSPKSA----------LLTQNGTGS--LPRNLAAT 1025
+ Q++ S + + A L Q L + A
Sbjct: 2260 DNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAV 2319
Query: 1026 LQDIETKRQLALQQKGQQVIEEQRRRLAE----LKQKAAAEAQCQWDALHGAAPFPAGPS 1081
+ K + L Q+ +++ +EQ RRL E + Q+ A E Q L S
Sbjct: 2320 QEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2379
Query: 1082 GFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSAS 1141
+ + + + R EE + + E + + + + + ++
Sbjct: 2380 AEAERLKLRVA-EMSRAQARAEEDAQRFRKQAEEIGEKLHRT------ELATQEKVTLVQ 2432
Query: 1142 GLDMGK--IEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESA 1199
L++ + + + L+EA AE R E ++E +L + L+ E + Q E+ LQ A
Sbjct: 2433 TLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ--LKSEEMQTVQQEQLLQETQA 2490
Query: 1200 RRQQ-LVEKEVKMREKQF 1216
+Q L EK+ ++ ++F
Sbjct: 2491 LQQSFLSEKDSLLQRERF 2508
Score = 56.2 bits (134), Expect = 2e-07
Identities = 155/719 (21%), Positives = 275/719 (38%), Gaps = 122/719 (16%)
Query: 576 KNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGE 635
K + E S E+ + R+ ER +Q+ E ER R E L +A+ EA
Sbjct: 1588 KTAQLERSLQEEHVAVAQLREEAERRAQQQAEA-ERAREEAERELERWQLKAN---EALR 1643
Query: 636 LPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTE 695
L E A + + + R + G A ++ E +++E L+++ E
Sbjct: 1644 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE-LEKQRQLAE 1702
Query: 696 STQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREA------- 748
T Q+ LA E+E ++ EQ + + + LE++L REA
Sbjct: 1703 GTAQQR------------LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR 1750
Query: 749 ---EMERALLQGERE---AERALLQKEQKAVDQLQEKLVALETGIQKERDKEA---EALE 799
E E A ++ E E A +A ++E ++ + ++ + E G +E +EA AL
Sbjct: 1751 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1810
Query: 800 TETK-----LFEDLEFQQLERESRVEEERELAGQGL-LRSKAEL-LRSIAKRKERLAILD 852
E K ED Q+ E E + E+ G+ L+++AE+ L+ ERL L
Sbjct: 1811 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA 1870
Query: 853 S----QAGQIRAQAVQE----SERLARDKNASLQLLQKEKEKL--TVLERRYHSLTGGRP 902
Q ++ QA Q ERLA+ + AS L+++K + T+ +RR
Sbjct: 1871 EDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR--------- 1921
Query: 903 FPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYR 962
+ E++L E+ AAA L S R
Sbjct: 1922 --------QVEEEILALKASFEK-------------AAAGKAELELELGRIRSNAEDTLR 1960
Query: 963 SKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNL 1022
SK E + R + + Q S+A + + A L + L
Sbjct: 1961 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE------VERL 2014
Query: 1023 AATLQDIETKRQLALQQKGQQV----IEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPA 1078
A +++ R+ A Q+ +Q+ Q+R AE K A A Q + +
Sbjct: 2015 KAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQ---- 2070
Query: 1079 GPSGFPPLMHHSILHHL----PAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSP 1134
S+L L A R EE E A E++ S + S
Sbjct: 2071 --------QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS-RRQVEEAERLKQSA 2121
Query: 1135 DNMSSASGLDMGKIEEMEK-----MLKEAHAEKNRLMESR--EREMELRRQALEEERRRR 1187
+ + A E++ K + A AE+ L + + + EME ++ E+ R++
Sbjct: 2122 EEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2181
Query: 1188 EQVERRLQS------ESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIE 1240
QVE+ L + E+ ++ L+++E++ + + ++A + + +E F ++ +E
Sbjct: 2182 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA--ARQRSQVEEELFSVRVQME 2238
Score = 50.1 bits (118), Expect = 1e-05
Identities = 115/550 (20%), Positives = 214/550 (38%), Gaps = 75/550 (13%)
Query: 695 ESTQQEH--EDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMER 752
E QQ H D + + V L E VL + + +++L +QL+ A+
Sbjct: 1161 ERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLG 1220
Query: 753 ALLQGEREAERAL----LQKEQKAVDQLQEKLVALETGIQKERDKEAEA---LETETKLF 805
A LQ R + + L Q +QL+++ LE I++ +K E +
Sbjct: 1221 AWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEE-IERHGEKVEECQRFAKQYINAI 1279
Query: 806 EDLEFQQLERESRVEEERELAGQGLLRSKAELLRS----IAKRKERLAILDSQAGQIRAQ 861
+D E Q + ++++E A + ++S +E + + L L SQ + ++
Sbjct: 1280 KDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISE 1339
Query: 862 AV---QESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLL 918
+ +E ERLA + A +E+E+L +E +L R + + K +
Sbjct: 1340 TLRRMEEEERLAEQQRA------EERERLAEVEA---ALEKQRQLAEAHAQAKAQAER-- 1388
Query: 919 PAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRS 978
A +L+Q QE + A +LQ R + E + + +
Sbjct: 1389 EAKELQQRMQEEVVRREEAAVDAQQQKR------SIQEELQQLRQSSEAEIQAKARQAEA 1442
Query: 979 GPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQ 1038
+ ++ V L + + + G + L A ++ E +++ A +
Sbjct: 1443 ----AERSRLRIEEEIRVVRLQLEATERQ----RGGAEGELQALRARAEEAEAQKRQAQE 1494
Query: 1039 Q----KGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHH 1094
+ + Q E QR+R AE++ + +A+ + A L
Sbjct: 1495 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA-----------------LQA 1537
Query: 1095 LPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKM 1154
L R + EE E +E + ++ ++ T SA + AS + K ++E+
Sbjct: 1538 LEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE--KTAQLERS 1595
Query: 1155 LKEAHAEKNRLMESREREMELRRQALEEERRRREQVER-----RLQSESARRQQLVEKEV 1209
L+E H +L E ER R Q E R RE+ ER +L++ A R +L +EV
Sbjct: 1596 LQEEHVAVAQLREEAER----RAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1651
Query: 1210 KMREKQFSQA 1219
++K +QA
Sbjct: 1652 -AQQKSLAQA 1660
Score = 35.8 bits (81), Expect = 0.29
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVE 1206
++EE E++ ++ AE+ + E +E +RQ E + + Q ER E+ QQ ++
Sbjct: 1343 RMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAER----EAKELQQRMQ 1398
Query: 1207 KEVKMREKQFSQARPLTR 1224
+EV RE+ A+ R
Sbjct: 1399 EEVVRREEAAVDAQQQKR 1416
>gi|41322910 plectin 1 isoform 7 [Homo sapiens]
Length = 4515
Score = 73.2 bits (178), Expect = 2e-12
Identities = 142/692 (20%), Positives = 275/692 (39%), Gaps = 80/692 (11%)
Query: 566 DLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYS 625
+L + + R R N+ + E LE RQRQ E+ R +R++ L E +
Sbjct: 1911 ELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAEERVQKSLAAEEEAA 1969
Query: 626 RADGGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEE 685
R L + A + A R R S R + A Q+ ++ E++
Sbjct: 1970 RQ----RKAALEEVERLKAKVEEARRLRERA-EQESARQLQLAQEAAQKRLQAEEKAHAF 2024
Query: 686 NLKEECSSTESTQQEHEDAPSTKLQGEVLAL-------EEERAQVLGHVEQLKVRVKELE 738
++++ + T Q+ E + +L+GE A EE R Q Q + +V+E E
Sbjct: 2025 AVQQKEQELQQTLQQ-EQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE 2083
Query: 739 QQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVAL------ETGIQKERD 792
+ L++SA E RA Q + AE+ + EQ+A + Q + AL + ++K +
Sbjct: 2084 R-LKQSAEEQAQARA--QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2140
Query: 793 KEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKE------ 846
+ L + ++ ++L +L+ E + ++ L + L R KAE + +R +
Sbjct: 2141 FAEQTLRQKAQVEQELTTLRLQLE-ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELF 2199
Query: 847 RLAILDSQAGQIRAQAVQESERL-ARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPK 905
+ + + +++A+ E+ L RDK+ + + LQ+E EK+ + L+
Sbjct: 2200 SVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAA 2259
Query: 906 TTSTLKEMEKLLLPAVDLEQWYQELMAGLGTG---PAAASPHSSPPPLPAKASRQLQVYR 962
L E E L E+ +E M + A A L + +R+LQ +
Sbjct: 2260 RLRQLAE-EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK 2318
Query: 963 SKMD---GEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLP 1019
+M E T RT S+ + +L + S + A
Sbjct: 2319 EQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA----EEDAQRF 2374
Query: 1020 RNLAATLQDIETKRQLALQQKGQ--QVIEEQRRRL---AELKQKAAAEAQCQWDALHGAA 1074
R A + + + +LA Q+K Q +E QR++ AE ++A AE + + + L A
Sbjct: 2375 RKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEA 2434
Query: 1075 PFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSP 1134
+ + EE + L+ + +++ S + +S
Sbjct: 2435 KLL---------------------QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2473
Query: 1135 DNMSSASGLDMGKI------------EEMEKMLKEAHAEKNRLMESREREMELRRQALEE 1182
+ + ++ EE ++ ++ E+ RL+ S E + +A E
Sbjct: 2474 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2533
Query: 1183 ERRRREQVERRLQSESARRQQLVEKEVKMREK 1214
RR++E++++ Q + + L E+ ++RE+
Sbjct: 2534 VRRKQEELQQLEQQRRQQEELLAEENQRLREQ 2565
Score = 72.0 bits (175), Expect = 4e-12
Identities = 144/673 (21%), Positives = 276/673 (41%), Gaps = 81/673 (12%)
Query: 591 EYHRRQRQERLR-----EQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAA 645
E RR+ +ER++ E+E R + LE + L A+ A E E S + A
Sbjct: 1948 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLA 2007
Query: 646 LALAGRR-PSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDA 704
A +R + A A +E Q L +++++ ++ L + E+ ++ E+A
Sbjct: 2008 QEAAQKRLQAEEKAHAFAVQQKE-----QELQQTLQQ-EQSVLDQLRGEAEAARRAAEEA 2061
Query: 705 PSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAR-EAEMERALLQGEREAER 763
++Q E E AQ VE+ + + E+Q Q A+ +A E+ + E+EA R
Sbjct: 2062 EEARVQAE-----REAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2116
Query: 764 ALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEER 823
Q EQ A+ Q Q A + ++K + + L + ++ ++L +L+ E + ++
Sbjct: 2117 RA-QAEQAALRQKQ----AADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE-TDHQK 2170
Query: 824 ELAGQGLLRSKAELLRSIAKRKE------RLAILDSQAGQIRAQAVQESERLA-RDKNAS 876
L + L R KAE + +R + + + + +++A+ E+ L RDK+ +
Sbjct: 2171 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2230
Query: 877 LQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGT 936
+ LQ+E EK+ + L+ L E E L E+ +E M +
Sbjct: 2231 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAE-EDLAQQRALAEKMLKEKMQAVQE 2289
Query: 937 GP---AAASPHSSPPPLPAKASRQLQVYRSKMD---GEATSPLPRTRSGPLPSSSGSSSS 990
A A L + +R+LQ + +M E T RT S+
Sbjct: 2290 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2349
Query: 991 SSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQ--QVIEEQ 1048
+ +L + S + A R A + + + +LA Q+K Q +E Q
Sbjct: 2350 AERLKLRVAEMSRAQARA----EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ 2405
Query: 1049 RRRL---AELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEG 1105
R++ AE ++A AE + + + L A + + EE
Sbjct: 2406 RQQSDHDAERLREAIAELEREKEKLQQEAKLL---------------------QLKSEEM 2444
Query: 1106 EHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRL 1165
+ L+ + +++ S + +S + ++ K + +E++ ++ A+ +L
Sbjct: 2445 QTVQQEQLLQETQALQQSFLSEKDSLLQRERF-----IEQEKAK-LEQLFQDEVAKAQQL 2498
Query: 1166 MESRERE---MELRRQAL----EEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQ 1218
E ++R+ ME RQ L EE RRR+ + E ++ + QQL ++ + E +
Sbjct: 2499 REEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEE 2558
Query: 1219 ARPLTRYLPIRKE 1231
+ L L + +E
Sbjct: 2559 NQRLREQLQLLEE 2571
Score = 68.2 bits (165), Expect = 5e-11
Identities = 156/694 (22%), Positives = 276/694 (39%), Gaps = 96/694 (13%)
Query: 596 QRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSR 655
Q+Q+R ++E+++L RQ E + A + A E L I E + L R
Sbjct: 1380 QQQKRSIQEELQQL-RQSSEAEIQAKARQAEA---AERSRL-RIEEEIRVVRLQLEATER 1434
Query: 656 GLAGASG-----RSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQ 710
GA G R+ E A +R ++ E ++ + + S Q E E A K +
Sbjct: 1435 QRGGAEGELQALRARAEEAEAQKR--QAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1492
Query: 711 GEVLALEEERAQVLGHVEQLKVRVKELEQQLQESA--REAEMERALLQGEREAERALLQK 768
E A E++RA L +E+L+++ +E E++L+++ R +++ AL +R AE L K
Sbjct: 1493 AEA-AREKQRA--LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSK 1549
Query: 769 EQKAVDQ-------LQEKLVA---LETGIQKERDKEAEALETETKLFEDLEFQQLERES- 817
++ LQE+ VA L ++ ++AEA + +LE QL+
Sbjct: 1550 RASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEA 1609
Query: 818 ---RVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKN 874
R++ E + L +++AE + A+R+ R + G+ QAV++ E ++
Sbjct: 1610 LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREAR------RRGKAEEQAVRQRELAEQELE 1663
Query: 875 ASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTL--KEMEKLLLPAVDLEQWYQELMA 932
QL + ++ E+ L + L +E+ +L A Q QEL A
Sbjct: 1664 KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1723
Query: 933 GLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRT---RSGPLPSSSGSSS 989
L A + + SR +SK EA + R + L + + +
Sbjct: 1724 ELAKVRAEMEVLLASKARAEEESRSTSE-KSKQRLEAEAGRFRELAEEAARLRALAEEAK 1782
Query: 990 SSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEE-- 1047
QL+ R + +L + T +I K + A ++ +++ E+
Sbjct: 1783 RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1842
Query: 1048 -QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGE 1106
QRRRL E + A+ + + L A+ ++ R + EE
Sbjct: 1843 FQRRRLEEQAAQHKADIEERLAQLRKASDSELE-------RQKGLVEDTLRQRRQVEE-- 1893
Query: 1107 HAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIE-EMEKMLKEAHAEKN-R 1164
+ L+L++S + GK E E+E ++AE R
Sbjct: 1894 ---EILALKASFEKAAA----------------------GKAELELELGRIRSNAEDTLR 1928
Query: 1165 LMESREREMELRRQALEEERRRREQVERRLQ------SESARRQQLVEKEVKMREKQFSQ 1218
E E E +RQ EE RRR + E R+Q E+AR+++ +EV+ + + +
Sbjct: 1929 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 1988
Query: 1219 ARPL--------TRYLPIRKEDFDLKTHIESSGH 1244
AR L R L + +E + E H
Sbjct: 1989 ARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH 2022
Score = 61.6 bits (148), Expect = 5e-09
Identities = 165/730 (22%), Positives = 285/730 (39%), Gaps = 129/730 (17%)
Query: 584 DNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEAT 643
+ E+ L E R + +ERL E E LE+QR L ++A EA EL +
Sbjct: 1313 EEEERLAEQQRAEERERLAEVEAA-LEKQRQ---LAEAHAQAKAQAEREAKEL----QQR 1364
Query: 644 AALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHED 703
+ R + A RS +E Q+L +S E + ++ ++ S + E+
Sbjct: 1365 MQEEVVRREEAAVDAQQQKRSIQEE---LQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1421
Query: 704 APSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGERE--- 760
+LQ E A E +R G ++ L+ R +E E Q +++ EAE R +Q E +
Sbjct: 1422 IRVVRLQLE--ATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKR 1479
Query: 761 -----------AERALLQKEQKAVDQLQEKLVALETGIQKERDKEAE-------ALETET 802
AE +++Q+A+ L+E + E ++ R E E ALET
Sbjct: 1480 QAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ 1539
Query: 803 KLFEDLEFQ-----------QLERE--------SRVEEERELAGQGLLRSKAELLRSIAK 843
+ E E Q QLER +++ EE E Q +++AE R A+
Sbjct: 1540 RSAE-AELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQ--QQAEAERAREEAE 1596
Query: 844 RK-ERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERR--------- 893
R+ ER + ++A ++R QA E +A+ K+ + +K+KE+ RR
Sbjct: 1597 RELERWQLKANEALRLRLQA----EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1652
Query: 894 ------YHSLTGGRPFPKTTS--TLKEMEKLLLPAVDLEQWYQ------ELMAGLGTGPA 939
L R + T+ L ++L+ + EQ Q E +A L A
Sbjct: 1653 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1712
Query: 940 AASPHSSPPPLP-AKASRQLQVY-----RSKMDGEATSPLPRTR--------------SG 979
AA+ AK +++V R++ + +TS + R +
Sbjct: 1713 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1772
Query: 980 PLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQ 1039
L + + + QL+ R + +L + T +I K + A +
Sbjct: 1773 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1832
Query: 1040 KGQQVIEE---QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLP 1096
+ +++ E+ QRRRL E + A+ + + L A+ L L
Sbjct: 1833 RLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASD--------SELERQKGLVEDT 1884
Query: 1097 AGRERGEEGEHAYDTLSLE--SSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKM 1154
+ R E E S E ++ E + G + + D + S ++ + +
Sbjct: 1885 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1944
Query: 1155 LKEAHAEK---NRLMESREREMELRRQ---ALEEERRRREQVE------RRLQSESARRQ 1202
+E + R+ +S E E RQ ALEE R + +VE R + ESAR+
Sbjct: 1945 AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQL 2004
Query: 1203 QLVEKEVKMR 1212
QL ++ + R
Sbjct: 2005 QLAQEAAQKR 2014
Score = 57.0 bits (136), Expect = 1e-07
Identities = 109/483 (22%), Positives = 190/483 (39%), Gaps = 82/483 (16%)
Query: 554 QSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQR 613
Q V+++L++ L++ T +KN + E RQR + E R++ +
Sbjct: 2148 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEE 2207
Query: 614 LETILNLCAEYSRA------DGGP-----EAGELPSIGEATAALALAGRRPSRGLAGASG 662
L + +RA D EA ++ + E A L++A + +R A
Sbjct: 2208 LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEE 2267
Query: 663 RSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQ 722
+++ +A + L E M+ E + + Q+E + +LQ + +E+ AQ
Sbjct: 2268 DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED----KEQMAQ 2323
Query: 723 VLGHVEQLKVRVKELEQQ--LQESA-------REAEMERALLQGEREAERALLQKEQKAV 773
L Q R E E+Q L+ SA R AEM RA + E +A+R +K
Sbjct: 2324 QLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRF-----RKQA 2378
Query: 774 DQLQEKLVALETGIQK---------------------------ERDKEAEALETETKLFE 806
+++ EKL E Q+ E ++E E L+ E KL +
Sbjct: 2379 EEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2438
Query: 807 --DLEFQQLERESRVEEERELAGQGLLRSKAELL---RSIAKRKERLAILDSQAGQIRAQ 861
E Q +++E ++E + L Q L K LL R I + K +L Q+
Sbjct: 2439 LKSEEMQTVQQEQLLQETQALQ-QSFLSEKDSLLQRERFIEQEKAKLE-------QLFQD 2490
Query: 862 AVQESERLARDKNASLQLLQKEKEKLTV----LERRYHSLTGG-----RPFPKTTSTLKE 912
V ++++L ++ Q +++E+++L RR H G + ++
Sbjct: 2491 EVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2550
Query: 913 MEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSP-PPLPAKASRQLQVYRSKMDGEATS 971
E+LL + Q +E + L AA HS A++ L R +DG A
Sbjct: 2551 QEELL---AEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAE 2607
Query: 972 PLP 974
P
Sbjct: 2608 AEP 2610
Score = 56.6 bits (135), Expect = 2e-07
Identities = 140/678 (20%), Positives = 259/678 (38%), Gaps = 97/678 (14%)
Query: 574 ERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEA 633
ER + + SD+E +RQ+ L E + R RQ E IL L A + +A G
Sbjct: 1861 ERLAQLRKASDSE--------LERQKGLVEDTL-RQRRQVEEEILALKASFEKAAAGKAE 1911
Query: 634 GELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSS 693
EL GR S + E A QR + E
Sbjct: 1912 LELE-----------LGRIRSNAEDTLRSKEQAELEAARQRQLAAEE------------- 1947
Query: 694 TESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERA 753
E ++E E+ L E A + +A L VE+LK +V+E ++L+E A
Sbjct: 1948 -ERRRREAEERVQKSLAAEEEAARQRKA-ALEEVERLKAKVEEA-RRLRERA-------- 1996
Query: 754 LLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQ-- 811
E+E+ R L ++ A +LQ + A +Q++ + + L+ E + + L +
Sbjct: 1997 ----EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2052
Query: 812 ------QLERESRVEEERELAGQGLLRSKAELLRSIAKRK-ERLAILDSQAGQIRAQAVQ 864
+ E+RV+ ERE A +AE L+ A+ + + A + A ++R +A Q
Sbjct: 2053 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ 2112
Query: 865 ESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVD-- 922
E+ R A+ + A+L+ +++ E H + + +E+ L L +
Sbjct: 2113 EAARRAQAEQAALR-----QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETD 2167
Query: 923 -----LEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTR 977
L++ Q L A S +L +++++ E + + R +
Sbjct: 2168 HQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDK 2227
Query: 978 SGPLPSSSGSSSSSSQLSVATLGRSPSPKSA----------LLTQNGTGS--LPRNLAAT 1025
+ Q++ S + + A L Q L + A
Sbjct: 2228 DNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAV 2287
Query: 1026 LQDIETKRQLALQQKGQQVIEEQRRRLAE----LKQKAAAEAQCQWDALHGAAPFPAGPS 1081
+ K + L Q+ +++ +EQ RRL E + Q+ A E Q L S
Sbjct: 2288 QEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2347
Query: 1082 GFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSAS 1141
+ + + + R EE + + E + + + + + ++
Sbjct: 2348 AEAERLKLRVA-EMSRAQARAEEDAQRFRKQAEEIGEKLHRT------ELATQEKVTLVQ 2400
Query: 1142 GLDMGK--IEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESA 1199
L++ + + + L+EA AE R E ++E +L + L+ E + Q E+ LQ A
Sbjct: 2401 TLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ--LKSEEMQTVQQEQLLQETQA 2458
Query: 1200 RRQQ-LVEKEVKMREKQF 1216
+Q L EK+ ++ ++F
Sbjct: 2459 LQQSFLSEKDSLLQRERF 2476
Score = 56.2 bits (134), Expect = 2e-07
Identities = 155/719 (21%), Positives = 275/719 (38%), Gaps = 122/719 (16%)
Query: 576 KNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGE 635
K + E S E+ + R+ ER +Q+ E ER R E L +A+ EA
Sbjct: 1556 KTAQLERSLQEEHVAVAQLREEAERRAQQQAEA-ERAREEAERELERWQLKAN---EALR 1611
Query: 636 LPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTE 695
L E A + + + R + G A ++ E +++E L+++ E
Sbjct: 1612 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE-LEKQRQLAE 1670
Query: 696 STQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREA------- 748
T Q+ LA E+E ++ EQ + + + LE++L REA
Sbjct: 1671 GTAQQR------------LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR 1718
Query: 749 ---EMERALLQGERE---AERALLQKEQKAVDQLQEKLVALETGIQKERDKEA---EALE 799
E E A ++ E E A +A ++E ++ + ++ + E G +E +EA AL
Sbjct: 1719 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1778
Query: 800 TETK-----LFEDLEFQQLERESRVEEERELAGQGL-LRSKAEL-LRSIAKRKERLAILD 852
E K ED Q+ E E + E+ G+ L+++AE+ L+ ERL L
Sbjct: 1779 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA 1838
Query: 853 S----QAGQIRAQAVQE----SERLARDKNASLQLLQKEKEKL--TVLERRYHSLTGGRP 902
Q ++ QA Q ERLA+ + AS L+++K + T+ +RR
Sbjct: 1839 EDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR--------- 1889
Query: 903 FPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYR 962
+ E++L E+ AAA L S R
Sbjct: 1890 --------QVEEEILALKASFEK-------------AAAGKAELELELGRIRSNAEDTLR 1928
Query: 963 SKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNL 1022
SK E + R + + Q S+A + + A L + L
Sbjct: 1929 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE------VERL 1982
Query: 1023 AATLQDIETKRQLALQQKGQQV----IEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPA 1078
A +++ R+ A Q+ +Q+ Q+R AE K A A Q + +
Sbjct: 1983 KAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQ---- 2038
Query: 1079 GPSGFPPLMHHSILHHL----PAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSP 1134
S+L L A R EE E A E++ S + S
Sbjct: 2039 --------QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS-RRQVEEAERLKQSA 2089
Query: 1135 DNMSSASGLDMGKIEEMEK-----MLKEAHAEKNRLMESR--EREMELRRQALEEERRRR 1187
+ + A E++ K + A AE+ L + + + EME ++ E+ R++
Sbjct: 2090 EEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2149
Query: 1188 EQVERRLQS------ESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIE 1240
QVE+ L + E+ ++ L+++E++ + + ++A + + +E F ++ +E
Sbjct: 2150 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA--ARQRSQVEEELFSVRVQME 2206
Score = 50.1 bits (118), Expect = 1e-05
Identities = 115/550 (20%), Positives = 214/550 (38%), Gaps = 75/550 (13%)
Query: 695 ESTQQEH--EDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMER 752
E QQ H D + + V L E VL + + +++L +QL+ A+
Sbjct: 1129 ERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLG 1188
Query: 753 ALLQGEREAERAL----LQKEQKAVDQLQEKLVALETGIQKERDKEAEA---LETETKLF 805
A LQ R + + L Q +QL+++ LE I++ +K E +
Sbjct: 1189 AWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEE-IERHGEKVEECQRFAKQYINAI 1247
Query: 806 EDLEFQQLERESRVEEERELAGQGLLRSKAELLRS----IAKRKERLAILDSQAGQIRAQ 861
+D E Q + ++++E A + ++S +E + + L L SQ + ++
Sbjct: 1248 KDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISE 1307
Query: 862 AV---QESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLL 918
+ +E ERLA + A +E+E+L +E +L R + + K +
Sbjct: 1308 TLRRMEEEERLAEQQRA------EERERLAEVEA---ALEKQRQLAEAHAQAKAQAER-- 1356
Query: 919 PAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRS 978
A +L+Q QE + A +LQ R + E + + +
Sbjct: 1357 EAKELQQRMQEEVVRREEAAVDAQQQKR------SIQEELQQLRQSSEAEIQAKARQAEA 1410
Query: 979 GPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQ 1038
+ ++ V L + + + G + L A ++ E +++ A +
Sbjct: 1411 ----AERSRLRIEEEIRVVRLQLEATERQ----RGGAEGELQALRARAEEAEAQKRQAQE 1462
Query: 1039 Q----KGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHH 1094
+ + Q E QR+R AE++ + +A+ + A L
Sbjct: 1463 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA-----------------LQA 1505
Query: 1095 LPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKM 1154
L R + EE E +E + ++ ++ T SA + AS + K ++E+
Sbjct: 1506 LEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE--KTAQLERS 1563
Query: 1155 LKEAHAEKNRLMESREREMELRRQALEEERRRREQVER-----RLQSESARRQQLVEKEV 1209
L+E H +L E ER R Q E R RE+ ER +L++ A R +L +EV
Sbjct: 1564 LQEEHVAVAQLREEAER----RAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1619
Query: 1210 KMREKQFSQA 1219
++K +QA
Sbjct: 1620 -AQQKSLAQA 1628
Score = 35.8 bits (81), Expect = 0.29
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVE 1206
++EE E++ ++ AE+ + E +E +RQ E + + Q ER E+ QQ ++
Sbjct: 1311 RMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAER----EAKELQQRMQ 1366
Query: 1207 KEVKMREKQFSQARPLTR 1224
+EV RE+ A+ R
Sbjct: 1367 EEVVRREEAAVDAQQQKR 1384
>gi|41322916 plectin 1 isoform 6 [Homo sapiens]
Length = 4684
Score = 73.2 bits (178), Expect = 2e-12
Identities = 142/692 (20%), Positives = 275/692 (39%), Gaps = 80/692 (11%)
Query: 566 DLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYS 625
+L + + R R N+ + E LE RQRQ E+ R +R++ L E +
Sbjct: 2080 ELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAEERVQKSLAAEEEAA 2138
Query: 626 RADGGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEE 685
R L + A + A R R S R + A Q+ ++ E++
Sbjct: 2139 RQ----RKAALEEVERLKAKVEEARRLRERA-EQESARQLQLAQEAAQKRLQAEEKAHAF 2193
Query: 686 NLKEECSSTESTQQEHEDAPSTKLQGEVLAL-------EEERAQVLGHVEQLKVRVKELE 738
++++ + T Q+ E + +L+GE A EE R Q Q + +V+E E
Sbjct: 2194 AVQQKEQELQQTLQQ-EQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE 2252
Query: 739 QQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVAL------ETGIQKERD 792
+ L++SA E RA Q + AE+ + EQ+A + Q + AL + ++K +
Sbjct: 2253 R-LKQSAEEQAQARA--QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2309
Query: 793 KEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKE------ 846
+ L + ++ ++L +L+ E + ++ L + L R KAE + +R +
Sbjct: 2310 FAEQTLRQKAQVEQELTTLRLQLE-ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELF 2368
Query: 847 RLAILDSQAGQIRAQAVQESERL-ARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPK 905
+ + + +++A+ E+ L RDK+ + + LQ+E EK+ + L+
Sbjct: 2369 SVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAA 2428
Query: 906 TTSTLKEMEKLLLPAVDLEQWYQELMAGLGTG---PAAASPHSSPPPLPAKASRQLQVYR 962
L E E L E+ +E M + A A L + +R+LQ +
Sbjct: 2429 RLRQLAE-EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK 2487
Query: 963 SKMD---GEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLP 1019
+M E T RT S+ + +L + S + A
Sbjct: 2488 EQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA----EEDAQRF 2543
Query: 1020 RNLAATLQDIETKRQLALQQKGQ--QVIEEQRRRL---AELKQKAAAEAQCQWDALHGAA 1074
R A + + + +LA Q+K Q +E QR++ AE ++A AE + + + L A
Sbjct: 2544 RKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEA 2603
Query: 1075 PFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSP 1134
+ + EE + L+ + +++ S + +S
Sbjct: 2604 KLL---------------------QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2642
Query: 1135 DNMSSASGLDMGKI------------EEMEKMLKEAHAEKNRLMESREREMELRRQALEE 1182
+ + ++ EE ++ ++ E+ RL+ S E + +A E
Sbjct: 2643 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2702
Query: 1183 ERRRREQVERRLQSESARRQQLVEKEVKMREK 1214
RR++E++++ Q + + L E+ ++RE+
Sbjct: 2703 VRRKQEELQQLEQQRRQQEELLAEENQRLREQ 2734
Score = 72.0 bits (175), Expect = 4e-12
Identities = 144/673 (21%), Positives = 276/673 (41%), Gaps = 81/673 (12%)
Query: 591 EYHRRQRQERLR-----EQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAA 645
E RR+ +ER++ E+E R + LE + L A+ A E E S + A
Sbjct: 2117 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLA 2176
Query: 646 LALAGRR-PSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDA 704
A +R + A A +E Q L +++++ ++ L + E+ ++ E+A
Sbjct: 2177 QEAAQKRLQAEEKAHAFAVQQKE-----QELQQTLQQ-EQSVLDQLRGEAEAARRAAEEA 2230
Query: 705 PSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAR-EAEMERALLQGEREAER 763
++Q E E AQ VE+ + + E+Q Q A+ +A E+ + E+EA R
Sbjct: 2231 EEARVQAE-----REAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2285
Query: 764 ALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEER 823
Q EQ A+ Q Q A + ++K + + L + ++ ++L +L+ E + ++
Sbjct: 2286 RA-QAEQAALRQKQ----AADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE-TDHQK 2339
Query: 824 ELAGQGLLRSKAELLRSIAKRKE------RLAILDSQAGQIRAQAVQESERLA-RDKNAS 876
L + L R KAE + +R + + + + +++A+ E+ L RDK+ +
Sbjct: 2340 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2399
Query: 877 LQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGT 936
+ LQ+E EK+ + L+ L E E L E+ +E M +
Sbjct: 2400 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAE-EDLAQQRALAEKMLKEKMQAVQE 2458
Query: 937 GP---AAASPHSSPPPLPAKASRQLQVYRSKMD---GEATSPLPRTRSGPLPSSSGSSSS 990
A A L + +R+LQ + +M E T RT S+
Sbjct: 2459 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2518
Query: 991 SSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQ--QVIEEQ 1048
+ +L + S + A R A + + + +LA Q+K Q +E Q
Sbjct: 2519 AERLKLRVAEMSRAQARA----EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ 2574
Query: 1049 RRRL---AELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEG 1105
R++ AE ++A AE + + + L A + + EE
Sbjct: 2575 RQQSDHDAERLREAIAELEREKEKLQQEAKLL---------------------QLKSEEM 2613
Query: 1106 EHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRL 1165
+ L+ + +++ S + +S + ++ K + +E++ ++ A+ +L
Sbjct: 2614 QTVQQEQLLQETQALQQSFLSEKDSLLQRERF-----IEQEKAK-LEQLFQDEVAKAQQL 2667
Query: 1166 MESRERE---MELRRQAL----EEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQ 1218
E ++R+ ME RQ L EE RRR+ + E ++ + QQL ++ + E +
Sbjct: 2668 REEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEE 2727
Query: 1219 ARPLTRYLPIRKE 1231
+ L L + +E
Sbjct: 2728 NQRLREQLQLLEE 2740
Score = 68.2 bits (165), Expect = 5e-11
Identities = 156/694 (22%), Positives = 276/694 (39%), Gaps = 96/694 (13%)
Query: 596 QRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSR 655
Q+Q+R ++E+++L RQ E + A + A E L I E + L R
Sbjct: 1549 QQQKRSIQEELQQL-RQSSEAEIQAKARQAEA---AERSRL-RIEEEIRVVRLQLEATER 1603
Query: 656 GLAGASG-----RSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQ 710
GA G R+ E A +R ++ E ++ + + S Q E E A K +
Sbjct: 1604 QRGGAEGELQALRARAEEAEAQKR--QAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1661
Query: 711 GEVLALEEERAQVLGHVEQLKVRVKELEQQLQESA--REAEMERALLQGEREAERALLQK 768
E A E++RA L +E+L+++ +E E++L+++ R +++ AL +R AE L K
Sbjct: 1662 AEA-AREKQRA--LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSK 1718
Query: 769 EQKAVDQ-------LQEKLVA---LETGIQKERDKEAEALETETKLFEDLEFQQLERES- 817
++ LQE+ VA L ++ ++AEA + +LE QL+
Sbjct: 1719 RASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEA 1778
Query: 818 ---RVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKN 874
R++ E + L +++AE + A+R+ R + G+ QAV++ E ++
Sbjct: 1779 LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREAR------RRGKAEEQAVRQRELAEQELE 1832
Query: 875 ASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTL--KEMEKLLLPAVDLEQWYQELMA 932
QL + ++ E+ L + L +E+ +L A Q QEL A
Sbjct: 1833 KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1892
Query: 933 GLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRT---RSGPLPSSSGSSS 989
L A + + SR +SK EA + R + L + + +
Sbjct: 1893 ELAKVRAEMEVLLASKARAEEESRSTSE-KSKQRLEAEAGRFRELAEEAARLRALAEEAK 1951
Query: 990 SSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEE-- 1047
QL+ R + +L + T +I K + A ++ +++ E+
Sbjct: 1952 RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 2011
Query: 1048 -QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGE 1106
QRRRL E + A+ + + L A+ ++ R + EE
Sbjct: 2012 FQRRRLEEQAAQHKADIEERLAQLRKASDSELE-------RQKGLVEDTLRQRRQVEE-- 2062
Query: 1107 HAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIE-EMEKMLKEAHAEKN-R 1164
+ L+L++S + GK E E+E ++AE R
Sbjct: 2063 ---EILALKASFEKAAA----------------------GKAELELELGRIRSNAEDTLR 2097
Query: 1165 LMESREREMELRRQALEEERRRREQVERRLQ------SESARRQQLVEKEVKMREKQFSQ 1218
E E E +RQ EE RRR + E R+Q E+AR+++ +EV+ + + +
Sbjct: 2098 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2157
Query: 1219 ARPL--------TRYLPIRKEDFDLKTHIESSGH 1244
AR L R L + +E + E H
Sbjct: 2158 ARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH 2191
Score = 61.6 bits (148), Expect = 5e-09
Identities = 165/730 (22%), Positives = 285/730 (39%), Gaps = 129/730 (17%)
Query: 584 DNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEAT 643
+ E+ L E R + +ERL E E LE+QR L ++A EA EL +
Sbjct: 1482 EEEERLAEQQRAEERERLAEVEAA-LEKQRQ---LAEAHAQAKAQAEREAKEL----QQR 1533
Query: 644 AALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHED 703
+ R + A RS +E Q+L +S E + ++ ++ S + E+
Sbjct: 1534 MQEEVVRREEAAVDAQQQKRSIQEE---LQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1590
Query: 704 APSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGERE--- 760
+LQ E A E +R G ++ L+ R +E E Q +++ EAE R +Q E +
Sbjct: 1591 IRVVRLQLE--ATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKR 1648
Query: 761 -----------AERALLQKEQKAVDQLQEKLVALETGIQKERDKEAE-------ALETET 802
AE +++Q+A+ L+E + E ++ R E E ALET
Sbjct: 1649 QAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ 1708
Query: 803 KLFEDLEFQ-----------QLERE--------SRVEEERELAGQGLLRSKAELLRSIAK 843
+ E E Q QLER +++ EE E Q +++AE R A+
Sbjct: 1709 RSAE-AELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQ--QQAEAERAREEAE 1765
Query: 844 RK-ERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERR--------- 893
R+ ER + ++A ++R QA E +A+ K+ + +K+KE+ RR
Sbjct: 1766 RELERWQLKANEALRLRLQA----EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1821
Query: 894 ------YHSLTGGRPFPKTTS--TLKEMEKLLLPAVDLEQWYQ------ELMAGLGTGPA 939
L R + T+ L ++L+ + EQ Q E +A L A
Sbjct: 1822 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1881
Query: 940 AASPHSSPPPLP-AKASRQLQVY-----RSKMDGEATSPLPRTR--------------SG 979
AA+ AK +++V R++ + +TS + R +
Sbjct: 1882 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1941
Query: 980 PLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQ 1039
L + + + QL+ R + +L + T +I K + A +
Sbjct: 1942 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 2001
Query: 1040 KGQQVIEE---QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLP 1096
+ +++ E+ QRRRL E + A+ + + L A+ L L
Sbjct: 2002 RLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASD--------SELERQKGLVEDT 2053
Query: 1097 AGRERGEEGEHAYDTLSLE--SSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKM 1154
+ R E E S E ++ E + G + + D + S ++ + +
Sbjct: 2054 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 2113
Query: 1155 LKEAHAEK---NRLMESREREMELRRQ---ALEEERRRREQVE------RRLQSESARRQ 1202
+E + R+ +S E E RQ ALEE R + +VE R + ESAR+
Sbjct: 2114 AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQL 2173
Query: 1203 QLVEKEVKMR 1212
QL ++ + R
Sbjct: 2174 QLAQEAAQKR 2183
Score = 57.0 bits (136), Expect = 1e-07
Identities = 109/483 (22%), Positives = 190/483 (39%), Gaps = 82/483 (16%)
Query: 554 QSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQR 613
Q V+++L++ L++ T +KN + E RQR + E R++ +
Sbjct: 2317 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEE 2376
Query: 614 LETILNLCAEYSRA------DGGP-----EAGELPSIGEATAALALAGRRPSRGLAGASG 662
L + +RA D EA ++ + E A L++A + +R A
Sbjct: 2377 LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEE 2436
Query: 663 RSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQ 722
+++ +A + L E M+ E + + Q+E + +LQ + +E+ AQ
Sbjct: 2437 DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED----KEQMAQ 2492
Query: 723 VLGHVEQLKVRVKELEQQ--LQESA-------REAEMERALLQGEREAERALLQKEQKAV 773
L Q R E E+Q L+ SA R AEM RA + E +A+R +K
Sbjct: 2493 QLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRF-----RKQA 2547
Query: 774 DQLQEKLVALETGIQK---------------------------ERDKEAEALETETKLFE 806
+++ EKL E Q+ E ++E E L+ E KL +
Sbjct: 2548 EEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2607
Query: 807 --DLEFQQLERESRVEEERELAGQGLLRSKAELL---RSIAKRKERLAILDSQAGQIRAQ 861
E Q +++E ++E + L Q L K LL R I + K +L Q+
Sbjct: 2608 LKSEEMQTVQQEQLLQETQALQ-QSFLSEKDSLLQRERFIEQEKAKLE-------QLFQD 2659
Query: 862 AVQESERLARDKNASLQLLQKEKEKLTV----LERRYHSLTGG-----RPFPKTTSTLKE 912
V ++++L ++ Q +++E+++L RR H G + ++
Sbjct: 2660 EVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2719
Query: 913 MEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSP-PPLPAKASRQLQVYRSKMDGEATS 971
E+LL + Q +E + L AA HS A++ L R +DG A
Sbjct: 2720 QEELL---AEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAE 2776
Query: 972 PLP 974
P
Sbjct: 2777 AEP 2779
Score = 56.6 bits (135), Expect = 2e-07
Identities = 140/678 (20%), Positives = 259/678 (38%), Gaps = 97/678 (14%)
Query: 574 ERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEA 633
ER + + SD+E +RQ+ L E + R RQ E IL L A + +A G
Sbjct: 2030 ERLAQLRKASDSE--------LERQKGLVEDTL-RQRRQVEEEILALKASFEKAAAGKAE 2080
Query: 634 GELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSS 693
EL GR S + E A QR + E
Sbjct: 2081 LELE-----------LGRIRSNAEDTLRSKEQAELEAARQRQLAAEE------------- 2116
Query: 694 TESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERA 753
E ++E E+ L E A + +A L VE+LK +V+E ++L+E A
Sbjct: 2117 -ERRRREAEERVQKSLAAEEEAARQRKA-ALEEVERLKAKVEEA-RRLRERA-------- 2165
Query: 754 LLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQ-- 811
E+E+ R L ++ A +LQ + A +Q++ + + L+ E + + L +
Sbjct: 2166 ----EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2221
Query: 812 ------QLERESRVEEERELAGQGLLRSKAELLRSIAKRK-ERLAILDSQAGQIRAQAVQ 864
+ E+RV+ ERE A +AE L+ A+ + + A + A ++R +A Q
Sbjct: 2222 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ 2281
Query: 865 ESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVD-- 922
E+ R A+ + A+L+ +++ E H + + +E+ L L +
Sbjct: 2282 EAARRAQAEQAALR-----QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETD 2336
Query: 923 -----LEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTR 977
L++ Q L A S +L +++++ E + + R +
Sbjct: 2337 HQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDK 2396
Query: 978 SGPLPSSSGSSSSSSQLSVATLGRSPSPKSA----------LLTQNGTGS--LPRNLAAT 1025
+ Q++ S + + A L Q L + A
Sbjct: 2397 DNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAV 2456
Query: 1026 LQDIETKRQLALQQKGQQVIEEQRRRLAE----LKQKAAAEAQCQWDALHGAAPFPAGPS 1081
+ K + L Q+ +++ +EQ RRL E + Q+ A E Q L S
Sbjct: 2457 QEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2516
Query: 1082 GFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSAS 1141
+ + + + R EE + + E + + + + + ++
Sbjct: 2517 AEAERLKLRVA-EMSRAQARAEEDAQRFRKQAEEIGEKLHRT------ELATQEKVTLVQ 2569
Query: 1142 GLDMGK--IEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESA 1199
L++ + + + L+EA AE R E ++E +L + L+ E + Q E+ LQ A
Sbjct: 2570 TLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ--LKSEEMQTVQQEQLLQETQA 2627
Query: 1200 RRQQ-LVEKEVKMREKQF 1216
+Q L EK+ ++ ++F
Sbjct: 2628 LQQSFLSEKDSLLQRERF 2645
Score = 56.2 bits (134), Expect = 2e-07
Identities = 155/719 (21%), Positives = 275/719 (38%), Gaps = 122/719 (16%)
Query: 576 KNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGE 635
K + E S E+ + R+ ER +Q+ E ER R E L +A+ EA
Sbjct: 1725 KTAQLERSLQEEHVAVAQLREEAERRAQQQAEA-ERAREEAERELERWQLKAN---EALR 1780
Query: 636 LPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTE 695
L E A + + + R + G A ++ E +++E L+++ E
Sbjct: 1781 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE-LEKQRQLAE 1839
Query: 696 STQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREA------- 748
T Q+ LA E+E ++ EQ + + + LE++L REA
Sbjct: 1840 GTAQQR------------LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR 1887
Query: 749 ---EMERALLQGERE---AERALLQKEQKAVDQLQEKLVALETGIQKERDKEA---EALE 799
E E A ++ E E A +A ++E ++ + ++ + E G +E +EA AL
Sbjct: 1888 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1947
Query: 800 TETK-----LFEDLEFQQLERESRVEEERELAGQGL-LRSKAEL-LRSIAKRKERLAILD 852
E K ED Q+ E E + E+ G+ L+++AE+ L+ ERL L
Sbjct: 1948 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA 2007
Query: 853 S----QAGQIRAQAVQE----SERLARDKNASLQLLQKEKEKL--TVLERRYHSLTGGRP 902
Q ++ QA Q ERLA+ + AS L+++K + T+ +RR
Sbjct: 2008 EDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR--------- 2058
Query: 903 FPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYR 962
+ E++L E+ AAA L S R
Sbjct: 2059 --------QVEEEILALKASFEK-------------AAAGKAELELELGRIRSNAEDTLR 2097
Query: 963 SKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNL 1022
SK E + R + + Q S+A + + A L + L
Sbjct: 2098 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE------VERL 2151
Query: 1023 AATLQDIETKRQLALQQKGQQV----IEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPA 1078
A +++ R+ A Q+ +Q+ Q+R AE K A A Q + +
Sbjct: 2152 KAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQ---- 2207
Query: 1079 GPSGFPPLMHHSILHHL----PAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSP 1134
S+L L A R EE E A E++ S + S
Sbjct: 2208 --------QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS-RRQVEEAERLKQSA 2258
Query: 1135 DNMSSASGLDMGKIEEMEK-----MLKEAHAEKNRLMESR--EREMELRRQALEEERRRR 1187
+ + A E++ K + A AE+ L + + + EME ++ E+ R++
Sbjct: 2259 EEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2318
Query: 1188 EQVERRLQS------ESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIE 1240
QVE+ L + E+ ++ L+++E++ + + ++A + + +E F ++ +E
Sbjct: 2319 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA--ARQRSQVEEELFSVRVQME 2375
Score = 50.1 bits (118), Expect = 1e-05
Identities = 115/550 (20%), Positives = 214/550 (38%), Gaps = 75/550 (13%)
Query: 695 ESTQQEH--EDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMER 752
E QQ H D + + V L E VL + + +++L +QL+ A+
Sbjct: 1298 ERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLG 1357
Query: 753 ALLQGEREAERAL----LQKEQKAVDQLQEKLVALETGIQKERDKEAEA---LETETKLF 805
A LQ R + + L Q +QL+++ LE I++ +K E +
Sbjct: 1358 AWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEE-IERHGEKVEECQRFAKQYINAI 1416
Query: 806 EDLEFQQLERESRVEEERELAGQGLLRSKAELLRS----IAKRKERLAILDSQAGQIRAQ 861
+D E Q + ++++E A + ++S +E + + L L SQ + ++
Sbjct: 1417 KDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISE 1476
Query: 862 AV---QESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLL 918
+ +E ERLA + A +E+E+L +E +L R + + K +
Sbjct: 1477 TLRRMEEEERLAEQQRA------EERERLAEVEA---ALEKQRQLAEAHAQAKAQAER-- 1525
Query: 919 PAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRS 978
A +L+Q QE + A +LQ R + E + + +
Sbjct: 1526 EAKELQQRMQEEVVRREEAAVDAQQQKR------SIQEELQQLRQSSEAEIQAKARQAEA 1579
Query: 979 GPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQ 1038
+ ++ V L + + + G + L A ++ E +++ A +
Sbjct: 1580 ----AERSRLRIEEEIRVVRLQLEATERQ----RGGAEGELQALRARAEEAEAQKRQAQE 1631
Query: 1039 Q----KGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHH 1094
+ + Q E QR+R AE++ + +A+ + A L
Sbjct: 1632 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA-----------------LQA 1674
Query: 1095 LPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKM 1154
L R + EE E +E + ++ ++ T SA + AS + K ++E+
Sbjct: 1675 LEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE--KTAQLERS 1732
Query: 1155 LKEAHAEKNRLMESREREMELRRQALEEERRRREQVER-----RLQSESARRQQLVEKEV 1209
L+E H +L E ER R Q E R RE+ ER +L++ A R +L +EV
Sbjct: 1733 LQEEHVAVAQLREEAER----RAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1788
Query: 1210 KMREKQFSQA 1219
++K +QA
Sbjct: 1789 -AQQKSLAQA 1797
Score = 35.8 bits (81), Expect = 0.29
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVE 1206
++EE E++ ++ AE+ + E +E +RQ E + + Q ER E+ QQ ++
Sbjct: 1480 RMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAER----EAKELQQRMQ 1535
Query: 1207 KEVKMREKQFSQARPLTR 1224
+EV RE+ A+ R
Sbjct: 1536 EEVVRREEAAVDAQQQKR 1553
>gi|41322908 plectin 1 isoform 3 [Homo sapiens]
Length = 4525
Score = 73.2 bits (178), Expect = 2e-12
Identities = 142/692 (20%), Positives = 275/692 (39%), Gaps = 80/692 (11%)
Query: 566 DLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYS 625
+L + + R R N+ + E LE RQRQ E+ R +R++ L E +
Sbjct: 1921 ELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAEERVQKSLAAEEEAA 1979
Query: 626 RADGGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEE 685
R L + A + A R R S R + A Q+ ++ E++
Sbjct: 1980 RQ----RKAALEEVERLKAKVEEARRLRERA-EQESARQLQLAQEAAQKRLQAEEKAHAF 2034
Query: 686 NLKEECSSTESTQQEHEDAPSTKLQGEVLAL-------EEERAQVLGHVEQLKVRVKELE 738
++++ + T Q+ E + +L+GE A EE R Q Q + +V+E E
Sbjct: 2035 AVQQKEQELQQTLQQ-EQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE 2093
Query: 739 QQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVAL------ETGIQKERD 792
+ L++SA E RA Q + AE+ + EQ+A + Q + AL + ++K +
Sbjct: 2094 R-LKQSAEEQAQARA--QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2150
Query: 793 KEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKE------ 846
+ L + ++ ++L +L+ E + ++ L + L R KAE + +R +
Sbjct: 2151 FAEQTLRQKAQVEQELTTLRLQLE-ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELF 2209
Query: 847 RLAILDSQAGQIRAQAVQESERL-ARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPK 905
+ + + +++A+ E+ L RDK+ + + LQ+E EK+ + L+
Sbjct: 2210 SVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAA 2269
Query: 906 TTSTLKEMEKLLLPAVDLEQWYQELMAGLGTG---PAAASPHSSPPPLPAKASRQLQVYR 962
L E E L E+ +E M + A A L + +R+LQ +
Sbjct: 2270 RLRQLAE-EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK 2328
Query: 963 SKMD---GEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLP 1019
+M E T RT S+ + +L + S + A
Sbjct: 2329 EQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA----EEDAQRF 2384
Query: 1020 RNLAATLQDIETKRQLALQQKGQ--QVIEEQRRRL---AELKQKAAAEAQCQWDALHGAA 1074
R A + + + +LA Q+K Q +E QR++ AE ++A AE + + + L A
Sbjct: 2385 RKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEA 2444
Query: 1075 PFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSP 1134
+ + EE + L+ + +++ S + +S
Sbjct: 2445 KLL---------------------QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2483
Query: 1135 DNMSSASGLDMGKI------------EEMEKMLKEAHAEKNRLMESREREMELRRQALEE 1182
+ + ++ EE ++ ++ E+ RL+ S E + +A E
Sbjct: 2484 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2543
Query: 1183 ERRRREQVERRLQSESARRQQLVEKEVKMREK 1214
RR++E++++ Q + + L E+ ++RE+
Sbjct: 2544 VRRKQEELQQLEQQRRQQEELLAEENQRLREQ 2575
Score = 72.0 bits (175), Expect = 4e-12
Identities = 144/673 (21%), Positives = 276/673 (41%), Gaps = 81/673 (12%)
Query: 591 EYHRRQRQERLR-----EQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAA 645
E RR+ +ER++ E+E R + LE + L A+ A E E S + A
Sbjct: 1958 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLA 2017
Query: 646 LALAGRR-PSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDA 704
A +R + A A +E Q L +++++ ++ L + E+ ++ E+A
Sbjct: 2018 QEAAQKRLQAEEKAHAFAVQQKE-----QELQQTLQQ-EQSVLDQLRGEAEAARRAAEEA 2071
Query: 705 PSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAR-EAEMERALLQGEREAER 763
++Q E E AQ VE+ + + E+Q Q A+ +A E+ + E+EA R
Sbjct: 2072 EEARVQAE-----REAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2126
Query: 764 ALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEER 823
Q EQ A+ Q Q A + ++K + + L + ++ ++L +L+ E + ++
Sbjct: 2127 RA-QAEQAALRQKQ----AADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE-TDHQK 2180
Query: 824 ELAGQGLLRSKAELLRSIAKRKE------RLAILDSQAGQIRAQAVQESERLA-RDKNAS 876
L + L R KAE + +R + + + + +++A+ E+ L RDK+ +
Sbjct: 2181 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2240
Query: 877 LQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGT 936
+ LQ+E EK+ + L+ L E E L E+ +E M +
Sbjct: 2241 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAE-EDLAQQRALAEKMLKEKMQAVQE 2299
Query: 937 GP---AAASPHSSPPPLPAKASRQLQVYRSKMD---GEATSPLPRTRSGPLPSSSGSSSS 990
A A L + +R+LQ + +M E T RT S+
Sbjct: 2300 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2359
Query: 991 SSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQ--QVIEEQ 1048
+ +L + S + A R A + + + +LA Q+K Q +E Q
Sbjct: 2360 AERLKLRVAEMSRAQARA----EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ 2415
Query: 1049 RRRL---AELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEG 1105
R++ AE ++A AE + + + L A + + EE
Sbjct: 2416 RQQSDHDAERLREAIAELEREKEKLQQEAKLL---------------------QLKSEEM 2454
Query: 1106 EHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRL 1165
+ L+ + +++ S + +S + ++ K + +E++ ++ A+ +L
Sbjct: 2455 QTVQQEQLLQETQALQQSFLSEKDSLLQRERF-----IEQEKAK-LEQLFQDEVAKAQQL 2508
Query: 1166 MESRERE---MELRRQAL----EEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQ 1218
E ++R+ ME RQ L EE RRR+ + E ++ + QQL ++ + E +
Sbjct: 2509 REEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEE 2568
Query: 1219 ARPLTRYLPIRKE 1231
+ L L + +E
Sbjct: 2569 NQRLREQLQLLEE 2581
Score = 68.2 bits (165), Expect = 5e-11
Identities = 156/694 (22%), Positives = 276/694 (39%), Gaps = 96/694 (13%)
Query: 596 QRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSR 655
Q+Q+R ++E+++L RQ E + A + A E L I E + L R
Sbjct: 1390 QQQKRSIQEELQQL-RQSSEAEIQAKARQAEA---AERSRL-RIEEEIRVVRLQLEATER 1444
Query: 656 GLAGASG-----RSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQ 710
GA G R+ E A +R ++ E ++ + + S Q E E A K +
Sbjct: 1445 QRGGAEGELQALRARAEEAEAQKR--QAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1502
Query: 711 GEVLALEEERAQVLGHVEQLKVRVKELEQQLQESA--REAEMERALLQGEREAERALLQK 768
E A E++RA L +E+L+++ +E E++L+++ R +++ AL +R AE L K
Sbjct: 1503 AEA-AREKQRA--LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSK 1559
Query: 769 EQKAVDQ-------LQEKLVA---LETGIQKERDKEAEALETETKLFEDLEFQQLERES- 817
++ LQE+ VA L ++ ++AEA + +LE QL+
Sbjct: 1560 RASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEA 1619
Query: 818 ---RVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKN 874
R++ E + L +++AE + A+R+ R + G+ QAV++ E ++
Sbjct: 1620 LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREAR------RRGKAEEQAVRQRELAEQELE 1673
Query: 875 ASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTL--KEMEKLLLPAVDLEQWYQELMA 932
QL + ++ E+ L + L +E+ +L A Q QEL A
Sbjct: 1674 KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1733
Query: 933 GLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRT---RSGPLPSSSGSSS 989
L A + + SR +SK EA + R + L + + +
Sbjct: 1734 ELAKVRAEMEVLLASKARAEEESRSTSE-KSKQRLEAEAGRFRELAEEAARLRALAEEAK 1792
Query: 990 SSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEE-- 1047
QL+ R + +L + T +I K + A ++ +++ E+
Sbjct: 1793 RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1852
Query: 1048 -QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGE 1106
QRRRL E + A+ + + L A+ ++ R + EE
Sbjct: 1853 FQRRRLEEQAAQHKADIEERLAQLRKASDSELE-------RQKGLVEDTLRQRRQVEE-- 1903
Query: 1107 HAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIE-EMEKMLKEAHAEKN-R 1164
+ L+L++S + GK E E+E ++AE R
Sbjct: 1904 ---EILALKASFEKAAA----------------------GKAELELELGRIRSNAEDTLR 1938
Query: 1165 LMESREREMELRRQALEEERRRREQVERRLQ------SESARRQQLVEKEVKMREKQFSQ 1218
E E E +RQ EE RRR + E R+Q E+AR+++ +EV+ + + +
Sbjct: 1939 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 1998
Query: 1219 ARPL--------TRYLPIRKEDFDLKTHIESSGH 1244
AR L R L + +E + E H
Sbjct: 1999 ARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH 2032
Score = 61.6 bits (148), Expect = 5e-09
Identities = 165/730 (22%), Positives = 285/730 (39%), Gaps = 129/730 (17%)
Query: 584 DNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEAT 643
+ E+ L E R + +ERL E E LE+QR L ++A EA EL +
Sbjct: 1323 EEEERLAEQQRAEERERLAEVEAA-LEKQRQ---LAEAHAQAKAQAEREAKEL----QQR 1374
Query: 644 AALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHED 703
+ R + A RS +E Q+L +S E + ++ ++ S + E+
Sbjct: 1375 MQEEVVRREEAAVDAQQQKRSIQEE---LQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1431
Query: 704 APSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGERE--- 760
+LQ E A E +R G ++ L+ R +E E Q +++ EAE R +Q E +
Sbjct: 1432 IRVVRLQLE--ATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKR 1489
Query: 761 -----------AERALLQKEQKAVDQLQEKLVALETGIQKERDKEAE-------ALETET 802
AE +++Q+A+ L+E + E ++ R E E ALET
Sbjct: 1490 QAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ 1549
Query: 803 KLFEDLEFQ-----------QLERE--------SRVEEERELAGQGLLRSKAELLRSIAK 843
+ E E Q QLER +++ EE E Q +++AE R A+
Sbjct: 1550 RSAE-AELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQ--QQAEAERAREEAE 1606
Query: 844 RK-ERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERR--------- 893
R+ ER + ++A ++R QA E +A+ K+ + +K+KE+ RR
Sbjct: 1607 RELERWQLKANEALRLRLQA----EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1662
Query: 894 ------YHSLTGGRPFPKTTS--TLKEMEKLLLPAVDLEQWYQ------ELMAGLGTGPA 939
L R + T+ L ++L+ + EQ Q E +A L A
Sbjct: 1663 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1722
Query: 940 AASPHSSPPPLP-AKASRQLQVY-----RSKMDGEATSPLPRTR--------------SG 979
AA+ AK +++V R++ + +TS + R +
Sbjct: 1723 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1782
Query: 980 PLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQ 1039
L + + + QL+ R + +L + T +I K + A +
Sbjct: 1783 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1842
Query: 1040 KGQQVIEE---QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLP 1096
+ +++ E+ QRRRL E + A+ + + L A+ L L
Sbjct: 1843 RLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASD--------SELERQKGLVEDT 1894
Query: 1097 AGRERGEEGEHAYDTLSLE--SSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKM 1154
+ R E E S E ++ E + G + + D + S ++ + +
Sbjct: 1895 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1954
Query: 1155 LKEAHAEK---NRLMESREREMELRRQ---ALEEERRRREQVE------RRLQSESARRQ 1202
+E + R+ +S E E RQ ALEE R + +VE R + ESAR+
Sbjct: 1955 AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQL 2014
Query: 1203 QLVEKEVKMR 1212
QL ++ + R
Sbjct: 2015 QLAQEAAQKR 2024
Score = 57.0 bits (136), Expect = 1e-07
Identities = 109/483 (22%), Positives = 190/483 (39%), Gaps = 82/483 (16%)
Query: 554 QSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQR 613
Q V+++L++ L++ T +KN + E RQR + E R++ +
Sbjct: 2158 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEE 2217
Query: 614 LETILNLCAEYSRA------DGGP-----EAGELPSIGEATAALALAGRRPSRGLAGASG 662
L + +RA D EA ++ + E A L++A + +R A
Sbjct: 2218 LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEE 2277
Query: 663 RSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQ 722
+++ +A + L E M+ E + + Q+E + +LQ + +E+ AQ
Sbjct: 2278 DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED----KEQMAQ 2333
Query: 723 VLGHVEQLKVRVKELEQQ--LQESA-------REAEMERALLQGEREAERALLQKEQKAV 773
L Q R E E+Q L+ SA R AEM RA + E +A+R +K
Sbjct: 2334 QLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRF-----RKQA 2388
Query: 774 DQLQEKLVALETGIQK---------------------------ERDKEAEALETETKLFE 806
+++ EKL E Q+ E ++E E L+ E KL +
Sbjct: 2389 EEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2448
Query: 807 --DLEFQQLERESRVEEERELAGQGLLRSKAELL---RSIAKRKERLAILDSQAGQIRAQ 861
E Q +++E ++E + L Q L K LL R I + K +L Q+
Sbjct: 2449 LKSEEMQTVQQEQLLQETQALQ-QSFLSEKDSLLQRERFIEQEKAKLE-------QLFQD 2500
Query: 862 AVQESERLARDKNASLQLLQKEKEKLTV----LERRYHSLTGG-----RPFPKTTSTLKE 912
V ++++L ++ Q +++E+++L RR H G + ++
Sbjct: 2501 EVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2560
Query: 913 MEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSP-PPLPAKASRQLQVYRSKMDGEATS 971
E+LL + Q +E + L AA HS A++ L R +DG A
Sbjct: 2561 QEELL---AEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAE 2617
Query: 972 PLP 974
P
Sbjct: 2618 AEP 2620
Score = 56.6 bits (135), Expect = 2e-07
Identities = 140/678 (20%), Positives = 259/678 (38%), Gaps = 97/678 (14%)
Query: 574 ERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEA 633
ER + + SD+E +RQ+ L E + R RQ E IL L A + +A G
Sbjct: 1871 ERLAQLRKASDSE--------LERQKGLVEDTL-RQRRQVEEEILALKASFEKAAAGKAE 1921
Query: 634 GELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSS 693
EL GR S + E A QR + E
Sbjct: 1922 LELE-----------LGRIRSNAEDTLRSKEQAELEAARQRQLAAEE------------- 1957
Query: 694 TESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERA 753
E ++E E+ L E A + +A L VE+LK +V+E ++L+E A
Sbjct: 1958 -ERRRREAEERVQKSLAAEEEAARQRKA-ALEEVERLKAKVEEA-RRLRERA-------- 2006
Query: 754 LLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQ-- 811
E+E+ R L ++ A +LQ + A +Q++ + + L+ E + + L +
Sbjct: 2007 ----EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2062
Query: 812 ------QLERESRVEEERELAGQGLLRSKAELLRSIAKRK-ERLAILDSQAGQIRAQAVQ 864
+ E+RV+ ERE A +AE L+ A+ + + A + A ++R +A Q
Sbjct: 2063 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ 2122
Query: 865 ESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVD-- 922
E+ R A+ + A+L+ +++ E H + + +E+ L L +
Sbjct: 2123 EAARRAQAEQAALR-----QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETD 2177
Query: 923 -----LEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTR 977
L++ Q L A S +L +++++ E + + R +
Sbjct: 2178 HQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDK 2237
Query: 978 SGPLPSSSGSSSSSSQLSVATLGRSPSPKSA----------LLTQNGTGS--LPRNLAAT 1025
+ Q++ S + + A L Q L + A
Sbjct: 2238 DNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAV 2297
Query: 1026 LQDIETKRQLALQQKGQQVIEEQRRRLAE----LKQKAAAEAQCQWDALHGAAPFPAGPS 1081
+ K + L Q+ +++ +EQ RRL E + Q+ A E Q L S
Sbjct: 2298 QEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2357
Query: 1082 GFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSAS 1141
+ + + + R EE + + E + + + + + ++
Sbjct: 2358 AEAERLKLRVA-EMSRAQARAEEDAQRFRKQAEEIGEKLHRT------ELATQEKVTLVQ 2410
Query: 1142 GLDMGK--IEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESA 1199
L++ + + + L+EA AE R E ++E +L + L+ E + Q E+ LQ A
Sbjct: 2411 TLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ--LKSEEMQTVQQEQLLQETQA 2468
Query: 1200 RRQQ-LVEKEVKMREKQF 1216
+Q L EK+ ++ ++F
Sbjct: 2469 LQQSFLSEKDSLLQRERF 2486
Score = 56.2 bits (134), Expect = 2e-07
Identities = 155/719 (21%), Positives = 275/719 (38%), Gaps = 122/719 (16%)
Query: 576 KNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGE 635
K + E S E+ + R+ ER +Q+ E ER R E L +A+ EA
Sbjct: 1566 KTAQLERSLQEEHVAVAQLREEAERRAQQQAEA-ERAREEAERELERWQLKAN---EALR 1621
Query: 636 LPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTE 695
L E A + + + R + G A ++ E +++E L+++ E
Sbjct: 1622 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE-LEKQRQLAE 1680
Query: 696 STQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREA------- 748
T Q+ LA E+E ++ EQ + + + LE++L REA
Sbjct: 1681 GTAQQR------------LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR 1728
Query: 749 ---EMERALLQGERE---AERALLQKEQKAVDQLQEKLVALETGIQKERDKEA---EALE 799
E E A ++ E E A +A ++E ++ + ++ + E G +E +EA AL
Sbjct: 1729 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1788
Query: 800 TETK-----LFEDLEFQQLERESRVEEERELAGQGL-LRSKAEL-LRSIAKRKERLAILD 852
E K ED Q+ E E + E+ G+ L+++AE+ L+ ERL L
Sbjct: 1789 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA 1848
Query: 853 S----QAGQIRAQAVQE----SERLARDKNASLQLLQKEKEKL--TVLERRYHSLTGGRP 902
Q ++ QA Q ERLA+ + AS L+++K + T+ +RR
Sbjct: 1849 EDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR--------- 1899
Query: 903 FPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYR 962
+ E++L E+ AAA L S R
Sbjct: 1900 --------QVEEEILALKASFEK-------------AAAGKAELELELGRIRSNAEDTLR 1938
Query: 963 SKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNL 1022
SK E + R + + Q S+A + + A L + L
Sbjct: 1939 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE------VERL 1992
Query: 1023 AATLQDIETKRQLALQQKGQQV----IEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPA 1078
A +++ R+ A Q+ +Q+ Q+R AE K A A Q + +
Sbjct: 1993 KAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQ---- 2048
Query: 1079 GPSGFPPLMHHSILHHL----PAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSP 1134
S+L L A R EE E A E++ S + S
Sbjct: 2049 --------QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS-RRQVEEAERLKQSA 2099
Query: 1135 DNMSSASGLDMGKIEEMEK-----MLKEAHAEKNRLMESR--EREMELRRQALEEERRRR 1187
+ + A E++ K + A AE+ L + + + EME ++ E+ R++
Sbjct: 2100 EEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2159
Query: 1188 EQVERRLQS------ESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIE 1240
QVE+ L + E+ ++ L+++E++ + + ++A + + +E F ++ +E
Sbjct: 2160 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA--ARQRSQVEEELFSVRVQME 2216
Score = 50.1 bits (118), Expect = 1e-05
Identities = 115/550 (20%), Positives = 214/550 (38%), Gaps = 75/550 (13%)
Query: 695 ESTQQEH--EDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMER 752
E QQ H D + + V L E VL + + +++L +QL+ A+
Sbjct: 1139 ERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLG 1198
Query: 753 ALLQGEREAERAL----LQKEQKAVDQLQEKLVALETGIQKERDKEAEA---LETETKLF 805
A LQ R + + L Q +QL+++ LE I++ +K E +
Sbjct: 1199 AWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEE-IERHGEKVEECQRFAKQYINAI 1257
Query: 806 EDLEFQQLERESRVEEERELAGQGLLRSKAELLRS----IAKRKERLAILDSQAGQIRAQ 861
+D E Q + ++++E A + ++S +E + + L L SQ + ++
Sbjct: 1258 KDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISE 1317
Query: 862 AV---QESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLL 918
+ +E ERLA + A +E+E+L +E +L R + + K +
Sbjct: 1318 TLRRMEEEERLAEQQRA------EERERLAEVEA---ALEKQRQLAEAHAQAKAQAER-- 1366
Query: 919 PAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRS 978
A +L+Q QE + A +LQ R + E + + +
Sbjct: 1367 EAKELQQRMQEEVVRREEAAVDAQQQKR------SIQEELQQLRQSSEAEIQAKARQAEA 1420
Query: 979 GPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQ 1038
+ ++ V L + + + G + L A ++ E +++ A +
Sbjct: 1421 ----AERSRLRIEEEIRVVRLQLEATERQ----RGGAEGELQALRARAEEAEAQKRQAQE 1472
Query: 1039 Q----KGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHH 1094
+ + Q E QR+R AE++ + +A+ + A L
Sbjct: 1473 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA-----------------LQA 1515
Query: 1095 LPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKM 1154
L R + EE E +E + ++ ++ T SA + AS + K ++E+
Sbjct: 1516 LEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE--KTAQLERS 1573
Query: 1155 LKEAHAEKNRLMESREREMELRRQALEEERRRREQVER-----RLQSESARRQQLVEKEV 1209
L+E H +L E ER R Q E R RE+ ER +L++ A R +L +EV
Sbjct: 1574 LQEEHVAVAQLREEAER----RAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1629
Query: 1210 KMREKQFSQA 1219
++K +QA
Sbjct: 1630 -AQQKSLAQA 1638
Score = 35.8 bits (81), Expect = 0.29
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVE 1206
++EE E++ ++ AE+ + E +E +RQ E + + Q ER E+ QQ ++
Sbjct: 1321 RMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAER----EAKELQQRMQ 1376
Query: 1207 KEVKMREKQFSQARPLTR 1224
+EV RE+ A+ R
Sbjct: 1377 EEVVRREEAAVDAQQQKR 1394
>gi|41322912 plectin 1 isoform 2 [Homo sapiens]
Length = 4533
Score = 73.2 bits (178), Expect = 2e-12
Identities = 142/692 (20%), Positives = 275/692 (39%), Gaps = 80/692 (11%)
Query: 566 DLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYS 625
+L + + R R N+ + E LE RQRQ E+ R +R++ L E +
Sbjct: 1929 ELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAEERVQKSLAAEEEAA 1987
Query: 626 RADGGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEE 685
R L + A + A R R S R + A Q+ ++ E++
Sbjct: 1988 RQ----RKAALEEVERLKAKVEEARRLRERA-EQESARQLQLAQEAAQKRLQAEEKAHAF 2042
Query: 686 NLKEECSSTESTQQEHEDAPSTKLQGEVLAL-------EEERAQVLGHVEQLKVRVKELE 738
++++ + T Q+ E + +L+GE A EE R Q Q + +V+E E
Sbjct: 2043 AVQQKEQELQQTLQQ-EQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE 2101
Query: 739 QQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVAL------ETGIQKERD 792
+ L++SA E RA Q + AE+ + EQ+A + Q + AL + ++K +
Sbjct: 2102 R-LKQSAEEQAQARA--QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2158
Query: 793 KEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKE------ 846
+ L + ++ ++L +L+ E + ++ L + L R KAE + +R +
Sbjct: 2159 FAEQTLRQKAQVEQELTTLRLQLE-ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELF 2217
Query: 847 RLAILDSQAGQIRAQAVQESERL-ARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPK 905
+ + + +++A+ E+ L RDK+ + + LQ+E EK+ + L+
Sbjct: 2218 SVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAA 2277
Query: 906 TTSTLKEMEKLLLPAVDLEQWYQELMAGLGTG---PAAASPHSSPPPLPAKASRQLQVYR 962
L E E L E+ +E M + A A L + +R+LQ +
Sbjct: 2278 RLRQLAE-EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK 2336
Query: 963 SKMD---GEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLP 1019
+M E T RT S+ + +L + S + A
Sbjct: 2337 EQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA----EEDAQRF 2392
Query: 1020 RNLAATLQDIETKRQLALQQKGQ--QVIEEQRRRL---AELKQKAAAEAQCQWDALHGAA 1074
R A + + + +LA Q+K Q +E QR++ AE ++A AE + + + L A
Sbjct: 2393 RKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEA 2452
Query: 1075 PFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSP 1134
+ + EE + L+ + +++ S + +S
Sbjct: 2453 KLL---------------------QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2491
Query: 1135 DNMSSASGLDMGKI------------EEMEKMLKEAHAEKNRLMESREREMELRRQALEE 1182
+ + ++ EE ++ ++ E+ RL+ S E + +A E
Sbjct: 2492 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2551
Query: 1183 ERRRREQVERRLQSESARRQQLVEKEVKMREK 1214
RR++E++++ Q + + L E+ ++RE+
Sbjct: 2552 VRRKQEELQQLEQQRRQQEELLAEENQRLREQ 2583
Score = 72.0 bits (175), Expect = 4e-12
Identities = 144/673 (21%), Positives = 276/673 (41%), Gaps = 81/673 (12%)
Query: 591 EYHRRQRQERLR-----EQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAA 645
E RR+ +ER++ E+E R + LE + L A+ A E E S + A
Sbjct: 1966 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLA 2025
Query: 646 LALAGRR-PSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDA 704
A +R + A A +E Q L +++++ ++ L + E+ ++ E+A
Sbjct: 2026 QEAAQKRLQAEEKAHAFAVQQKE-----QELQQTLQQ-EQSVLDQLRGEAEAARRAAEEA 2079
Query: 705 PSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAR-EAEMERALLQGEREAER 763
++Q E E AQ VE+ + + E+Q Q A+ +A E+ + E+EA R
Sbjct: 2080 EEARVQAE-----REAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2134
Query: 764 ALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEER 823
Q EQ A+ Q Q A + ++K + + L + ++ ++L +L+ E + ++
Sbjct: 2135 RA-QAEQAALRQKQ----AADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE-TDHQK 2188
Query: 824 ELAGQGLLRSKAELLRSIAKRKE------RLAILDSQAGQIRAQAVQESERLA-RDKNAS 876
L + L R KAE + +R + + + + +++A+ E+ L RDK+ +
Sbjct: 2189 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2248
Query: 877 LQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGT 936
+ LQ+E EK+ + L+ L E E L E+ +E M +
Sbjct: 2249 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAE-EDLAQQRALAEKMLKEKMQAVQE 2307
Query: 937 GP---AAASPHSSPPPLPAKASRQLQVYRSKMD---GEATSPLPRTRSGPLPSSSGSSSS 990
A A L + +R+LQ + +M E T RT S+
Sbjct: 2308 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2367
Query: 991 SSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQ--QVIEEQ 1048
+ +L + S + A R A + + + +LA Q+K Q +E Q
Sbjct: 2368 AERLKLRVAEMSRAQARA----EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ 2423
Query: 1049 RRRL---AELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEG 1105
R++ AE ++A AE + + + L A + + EE
Sbjct: 2424 RQQSDHDAERLREAIAELEREKEKLQQEAKLL---------------------QLKSEEM 2462
Query: 1106 EHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRL 1165
+ L+ + +++ S + +S + ++ K + +E++ ++ A+ +L
Sbjct: 2463 QTVQQEQLLQETQALQQSFLSEKDSLLQRERF-----IEQEKAK-LEQLFQDEVAKAQQL 2516
Query: 1166 MESRERE---MELRRQAL----EEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQ 1218
E ++R+ ME RQ L EE RRR+ + E ++ + QQL ++ + E +
Sbjct: 2517 REEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEE 2576
Query: 1219 ARPLTRYLPIRKE 1231
+ L L + +E
Sbjct: 2577 NQRLREQLQLLEE 2589
Score = 68.2 bits (165), Expect = 5e-11
Identities = 156/694 (22%), Positives = 276/694 (39%), Gaps = 96/694 (13%)
Query: 596 QRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSR 655
Q+Q+R ++E+++L RQ E + A + A E L I E + L R
Sbjct: 1398 QQQKRSIQEELQQL-RQSSEAEIQAKARQAEA---AERSRL-RIEEEIRVVRLQLEATER 1452
Query: 656 GLAGASG-----RSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQ 710
GA G R+ E A +R ++ E ++ + + S Q E E A K +
Sbjct: 1453 QRGGAEGELQALRARAEEAEAQKR--QAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1510
Query: 711 GEVLALEEERAQVLGHVEQLKVRVKELEQQLQESA--REAEMERALLQGEREAERALLQK 768
E A E++RA L +E+L+++ +E E++L+++ R +++ AL +R AE L K
Sbjct: 1511 AEA-AREKQRA--LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSK 1567
Query: 769 EQKAVDQ-------LQEKLVA---LETGIQKERDKEAEALETETKLFEDLEFQQLERES- 817
++ LQE+ VA L ++ ++AEA + +LE QL+
Sbjct: 1568 RASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEA 1627
Query: 818 ---RVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKN 874
R++ E + L +++AE + A+R+ R + G+ QAV++ E ++
Sbjct: 1628 LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREAR------RRGKAEEQAVRQRELAEQELE 1681
Query: 875 ASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTL--KEMEKLLLPAVDLEQWYQELMA 932
QL + ++ E+ L + L +E+ +L A Q QEL A
Sbjct: 1682 KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1741
Query: 933 GLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRT---RSGPLPSSSGSSS 989
L A + + SR +SK EA + R + L + + +
Sbjct: 1742 ELAKVRAEMEVLLASKARAEEESRSTSE-KSKQRLEAEAGRFRELAEEAARLRALAEEAK 1800
Query: 990 SSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEE-- 1047
QL+ R + +L + T +I K + A ++ +++ E+
Sbjct: 1801 RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1860
Query: 1048 -QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGE 1106
QRRRL E + A+ + + L A+ ++ R + EE
Sbjct: 1861 FQRRRLEEQAAQHKADIEERLAQLRKASDSELE-------RQKGLVEDTLRQRRQVEE-- 1911
Query: 1107 HAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIE-EMEKMLKEAHAEKN-R 1164
+ L+L++S + GK E E+E ++AE R
Sbjct: 1912 ---EILALKASFEKAAA----------------------GKAELELELGRIRSNAEDTLR 1946
Query: 1165 LMESREREMELRRQALEEERRRREQVERRLQ------SESARRQQLVEKEVKMREKQFSQ 1218
E E E +RQ EE RRR + E R+Q E+AR+++ +EV+ + + +
Sbjct: 1947 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2006
Query: 1219 ARPL--------TRYLPIRKEDFDLKTHIESSGH 1244
AR L R L + +E + E H
Sbjct: 2007 ARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH 2040
Score = 61.6 bits (148), Expect = 5e-09
Identities = 165/730 (22%), Positives = 285/730 (39%), Gaps = 129/730 (17%)
Query: 584 DNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEAT 643
+ E+ L E R + +ERL E E LE+QR L ++A EA EL +
Sbjct: 1331 EEEERLAEQQRAEERERLAEVEAA-LEKQRQ---LAEAHAQAKAQAEREAKEL----QQR 1382
Query: 644 AALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHED 703
+ R + A RS +E Q+L +S E + ++ ++ S + E+
Sbjct: 1383 MQEEVVRREEAAVDAQQQKRSIQEE---LQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1439
Query: 704 APSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGERE--- 760
+LQ E A E +R G ++ L+ R +E E Q +++ EAE R +Q E +
Sbjct: 1440 IRVVRLQLE--ATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKR 1497
Query: 761 -----------AERALLQKEQKAVDQLQEKLVALETGIQKERDKEAE-------ALETET 802
AE +++Q+A+ L+E + E ++ R E E ALET
Sbjct: 1498 QAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ 1557
Query: 803 KLFEDLEFQ-----------QLERE--------SRVEEERELAGQGLLRSKAELLRSIAK 843
+ E E Q QLER +++ EE E Q +++AE R A+
Sbjct: 1558 RSAE-AELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQ--QQAEAERAREEAE 1614
Query: 844 RK-ERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERR--------- 893
R+ ER + ++A ++R QA E +A+ K+ + +K+KE+ RR
Sbjct: 1615 RELERWQLKANEALRLRLQA----EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1670
Query: 894 ------YHSLTGGRPFPKTTS--TLKEMEKLLLPAVDLEQWYQ------ELMAGLGTGPA 939
L R + T+ L ++L+ + EQ Q E +A L A
Sbjct: 1671 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1730
Query: 940 AASPHSSPPPLP-AKASRQLQVY-----RSKMDGEATSPLPRTR--------------SG 979
AA+ AK +++V R++ + +TS + R +
Sbjct: 1731 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1790
Query: 980 PLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQ 1039
L + + + QL+ R + +L + T +I K + A +
Sbjct: 1791 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1850
Query: 1040 KGQQVIEE---QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLP 1096
+ +++ E+ QRRRL E + A+ + + L A+ L L
Sbjct: 1851 RLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASD--------SELERQKGLVEDT 1902
Query: 1097 AGRERGEEGEHAYDTLSLE--SSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKM 1154
+ R E E S E ++ E + G + + D + S ++ + +
Sbjct: 1903 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 1962
Query: 1155 LKEAHAEK---NRLMESREREMELRRQ---ALEEERRRREQVE------RRLQSESARRQ 1202
+E + R+ +S E E RQ ALEE R + +VE R + ESAR+
Sbjct: 1963 AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQL 2022
Query: 1203 QLVEKEVKMR 1212
QL ++ + R
Sbjct: 2023 QLAQEAAQKR 2032
Score = 57.0 bits (136), Expect = 1e-07
Identities = 109/483 (22%), Positives = 190/483 (39%), Gaps = 82/483 (16%)
Query: 554 QSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQR 613
Q V+++L++ L++ T +KN + E RQR + E R++ +
Sbjct: 2166 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEE 2225
Query: 614 LETILNLCAEYSRA------DGGP-----EAGELPSIGEATAALALAGRRPSRGLAGASG 662
L + +RA D EA ++ + E A L++A + +R A
Sbjct: 2226 LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEE 2285
Query: 663 RSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQ 722
+++ +A + L E M+ E + + Q+E + +LQ + +E+ AQ
Sbjct: 2286 DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED----KEQMAQ 2341
Query: 723 VLGHVEQLKVRVKELEQQ--LQESA-------REAEMERALLQGEREAERALLQKEQKAV 773
L Q R E E+Q L+ SA R AEM RA + E +A+R +K
Sbjct: 2342 QLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRF-----RKQA 2396
Query: 774 DQLQEKLVALETGIQK---------------------------ERDKEAEALETETKLFE 806
+++ EKL E Q+ E ++E E L+ E KL +
Sbjct: 2397 EEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2456
Query: 807 --DLEFQQLERESRVEEERELAGQGLLRSKAELL---RSIAKRKERLAILDSQAGQIRAQ 861
E Q +++E ++E + L Q L K LL R I + K +L Q+
Sbjct: 2457 LKSEEMQTVQQEQLLQETQALQ-QSFLSEKDSLLQRERFIEQEKAKLE-------QLFQD 2508
Query: 862 AVQESERLARDKNASLQLLQKEKEKLTV----LERRYHSLTGG-----RPFPKTTSTLKE 912
V ++++L ++ Q +++E+++L RR H G + ++
Sbjct: 2509 EVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2568
Query: 913 MEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSP-PPLPAKASRQLQVYRSKMDGEATS 971
E+LL + Q +E + L AA HS A++ L R +DG A
Sbjct: 2569 QEELL---AEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAE 2625
Query: 972 PLP 974
P
Sbjct: 2626 AEP 2628
Score = 56.6 bits (135), Expect = 2e-07
Identities = 140/678 (20%), Positives = 259/678 (38%), Gaps = 97/678 (14%)
Query: 574 ERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEA 633
ER + + SD+E +RQ+ L E + R RQ E IL L A + +A G
Sbjct: 1879 ERLAQLRKASDSE--------LERQKGLVEDTL-RQRRQVEEEILALKASFEKAAAGKAE 1929
Query: 634 GELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSS 693
EL GR S + E A QR + E
Sbjct: 1930 LELE-----------LGRIRSNAEDTLRSKEQAELEAARQRQLAAEE------------- 1965
Query: 694 TESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERA 753
E ++E E+ L E A + +A L VE+LK +V+E ++L+E A
Sbjct: 1966 -ERRRREAEERVQKSLAAEEEAARQRKA-ALEEVERLKAKVEEA-RRLRERA-------- 2014
Query: 754 LLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQ-- 811
E+E+ R L ++ A +LQ + A +Q++ + + L+ E + + L +
Sbjct: 2015 ----EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2070
Query: 812 ------QLERESRVEEERELAGQGLLRSKAELLRSIAKRK-ERLAILDSQAGQIRAQAVQ 864
+ E+RV+ ERE A +AE L+ A+ + + A + A ++R +A Q
Sbjct: 2071 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ 2130
Query: 865 ESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVD-- 922
E+ R A+ + A+L+ +++ E H + + +E+ L L +
Sbjct: 2131 EAARRAQAEQAALR-----QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETD 2185
Query: 923 -----LEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTR 977
L++ Q L A S +L +++++ E + + R +
Sbjct: 2186 HQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDK 2245
Query: 978 SGPLPSSSGSSSSSSQLSVATLGRSPSPKSA----------LLTQNGTGS--LPRNLAAT 1025
+ Q++ S + + A L Q L + A
Sbjct: 2246 DNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAV 2305
Query: 1026 LQDIETKRQLALQQKGQQVIEEQRRRLAE----LKQKAAAEAQCQWDALHGAAPFPAGPS 1081
+ K + L Q+ +++ +EQ RRL E + Q+ A E Q L S
Sbjct: 2306 QEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2365
Query: 1082 GFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSAS 1141
+ + + + R EE + + E + + + + + ++
Sbjct: 2366 AEAERLKLRVA-EMSRAQARAEEDAQRFRKQAEEIGEKLHRT------ELATQEKVTLVQ 2418
Query: 1142 GLDMGK--IEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESA 1199
L++ + + + L+EA AE R E ++E +L + L+ E + Q E+ LQ A
Sbjct: 2419 TLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ--LKSEEMQTVQQEQLLQETQA 2476
Query: 1200 RRQQ-LVEKEVKMREKQF 1216
+Q L EK+ ++ ++F
Sbjct: 2477 LQQSFLSEKDSLLQRERF 2494
Score = 56.2 bits (134), Expect = 2e-07
Identities = 155/719 (21%), Positives = 275/719 (38%), Gaps = 122/719 (16%)
Query: 576 KNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGE 635
K + E S E+ + R+ ER +Q+ E ER R E L +A+ EA
Sbjct: 1574 KTAQLERSLQEEHVAVAQLREEAERRAQQQAEA-ERAREEAERELERWQLKAN---EALR 1629
Query: 636 LPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTE 695
L E A + + + R + G A ++ E +++E L+++ E
Sbjct: 1630 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE-LEKQRQLAE 1688
Query: 696 STQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREA------- 748
T Q+ LA E+E ++ EQ + + + LE++L REA
Sbjct: 1689 GTAQQR------------LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR 1736
Query: 749 ---EMERALLQGERE---AERALLQKEQKAVDQLQEKLVALETGIQKERDKEA---EALE 799
E E A ++ E E A +A ++E ++ + ++ + E G +E +EA AL
Sbjct: 1737 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1796
Query: 800 TETK-----LFEDLEFQQLERESRVEEERELAGQGL-LRSKAEL-LRSIAKRKERLAILD 852
E K ED Q+ E E + E+ G+ L+++AE+ L+ ERL L
Sbjct: 1797 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA 1856
Query: 853 S----QAGQIRAQAVQE----SERLARDKNASLQLLQKEKEKL--TVLERRYHSLTGGRP 902
Q ++ QA Q ERLA+ + AS L+++K + T+ +RR
Sbjct: 1857 EDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR--------- 1907
Query: 903 FPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYR 962
+ E++L E+ AAA L S R
Sbjct: 1908 --------QVEEEILALKASFEK-------------AAAGKAELELELGRIRSNAEDTLR 1946
Query: 963 SKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNL 1022
SK E + R + + Q S+A + + A L + L
Sbjct: 1947 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE------VERL 2000
Query: 1023 AATLQDIETKRQLALQQKGQQV----IEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPA 1078
A +++ R+ A Q+ +Q+ Q+R AE K A A Q + +
Sbjct: 2001 KAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQ---- 2056
Query: 1079 GPSGFPPLMHHSILHHL----PAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSP 1134
S+L L A R EE E A E++ S + S
Sbjct: 2057 --------QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS-RRQVEEAERLKQSA 2107
Query: 1135 DNMSSASGLDMGKIEEMEK-----MLKEAHAEKNRLMESR--EREMELRRQALEEERRRR 1187
+ + A E++ K + A AE+ L + + + EME ++ E+ R++
Sbjct: 2108 EEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2167
Query: 1188 EQVERRLQS------ESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIE 1240
QVE+ L + E+ ++ L+++E++ + + ++A + + +E F ++ +E
Sbjct: 2168 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA--ARQRSQVEEELFSVRVQME 2224
Score = 50.1 bits (118), Expect = 1e-05
Identities = 115/550 (20%), Positives = 214/550 (38%), Gaps = 75/550 (13%)
Query: 695 ESTQQEH--EDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMER 752
E QQ H D + + V L E VL + + +++L +QL+ A+
Sbjct: 1147 ERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLG 1206
Query: 753 ALLQGEREAERAL----LQKEQKAVDQLQEKLVALETGIQKERDKEAEA---LETETKLF 805
A LQ R + + L Q +QL+++ LE I++ +K E +
Sbjct: 1207 AWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEE-IERHGEKVEECQRFAKQYINAI 1265
Query: 806 EDLEFQQLERESRVEEERELAGQGLLRSKAELLRS----IAKRKERLAILDSQAGQIRAQ 861
+D E Q + ++++E A + ++S +E + + L L SQ + ++
Sbjct: 1266 KDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISE 1325
Query: 862 AV---QESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLL 918
+ +E ERLA + A +E+E+L +E +L R + + K +
Sbjct: 1326 TLRRMEEEERLAEQQRA------EERERLAEVEA---ALEKQRQLAEAHAQAKAQAER-- 1374
Query: 919 PAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRS 978
A +L+Q QE + A +LQ R + E + + +
Sbjct: 1375 EAKELQQRMQEEVVRREEAAVDAQQQKR------SIQEELQQLRQSSEAEIQAKARQAEA 1428
Query: 979 GPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQ 1038
+ ++ V L + + + G + L A ++ E +++ A +
Sbjct: 1429 ----AERSRLRIEEEIRVVRLQLEATERQ----RGGAEGELQALRARAEEAEAQKRQAQE 1480
Query: 1039 Q----KGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHH 1094
+ + Q E QR+R AE++ + +A+ + A L
Sbjct: 1481 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA-----------------LQA 1523
Query: 1095 LPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKM 1154
L R + EE E +E + ++ ++ T SA + AS + K ++E+
Sbjct: 1524 LEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE--KTAQLERS 1581
Query: 1155 LKEAHAEKNRLMESREREMELRRQALEEERRRREQVER-----RLQSESARRQQLVEKEV 1209
L+E H +L E ER R Q E R RE+ ER +L++ A R +L +EV
Sbjct: 1582 LQEEHVAVAQLREEAER----RAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1637
Query: 1210 KMREKQFSQA 1219
++K +QA
Sbjct: 1638 -AQQKSLAQA 1646
Score = 35.8 bits (81), Expect = 0.29
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVE 1206
++EE E++ ++ AE+ + E +E +RQ E + + Q ER E+ QQ ++
Sbjct: 1329 RMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAER----EAKELQQRMQ 1384
Query: 1207 KEVKMREKQFSQARPLTR 1224
+EV RE+ A+ R
Sbjct: 1385 EEVVRREEAAVDAQQQKR 1402
>gi|47607492 plectin 1 isoform 1 [Homo sapiens]
Length = 4574
Score = 73.2 bits (178), Expect = 2e-12
Identities = 142/692 (20%), Positives = 275/692 (39%), Gaps = 80/692 (11%)
Query: 566 DLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYS 625
+L + + R R N+ + E LE RQRQ E+ R +R++ L E +
Sbjct: 1970 ELELELGRIRSNAEDTLRSKEQAELEA-ARQRQLAAEEERRRREAEERVQKSLAAEEEAA 2028
Query: 626 RADGGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEE 685
R L + A + A R R S R + A Q+ ++ E++
Sbjct: 2029 RQ----RKAALEEVERLKAKVEEARRLRERA-EQESARQLQLAQEAAQKRLQAEEKAHAF 2083
Query: 686 NLKEECSSTESTQQEHEDAPSTKLQGEVLAL-------EEERAQVLGHVEQLKVRVKELE 738
++++ + T Q+ E + +L+GE A EE R Q Q + +V+E E
Sbjct: 2084 AVQQKEQELQQTLQQ-EQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQSRRQVEEAE 2142
Query: 739 QQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVAL------ETGIQKERD 792
+ L++SA E RA Q + AE+ + EQ+A + Q + AL + ++K +
Sbjct: 2143 R-LKQSAEEQAQARA--QAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKK 2199
Query: 793 KEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKE------ 846
+ L + ++ ++L +L+ E + ++ L + L R KAE + +R +
Sbjct: 2200 FAEQTLRQKAQVEQELTTLRLQLE-ETDHQKNLLDEELQRLKAEATEAARQRSQVEEELF 2258
Query: 847 RLAILDSQAGQIRAQAVQESERL-ARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPK 905
+ + + +++A+ E+ L RDK+ + + LQ+E EK+ + L+
Sbjct: 2259 SVRVQMEELSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAA 2318
Query: 906 TTSTLKEMEKLLLPAVDLEQWYQELMAGLGTG---PAAASPHSSPPPLPAKASRQLQVYR 962
L E E L E+ +E M + A A L + +R+LQ +
Sbjct: 2319 RLRQLAE-EDLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQEDK 2377
Query: 963 SKMD---GEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLP 1019
+M E T RT S+ + +L + S + A
Sbjct: 2378 EQMAQQLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARA----EEDAQRF 2433
Query: 1020 RNLAATLQDIETKRQLALQQKGQ--QVIEEQRRRL---AELKQKAAAEAQCQWDALHGAA 1074
R A + + + +LA Q+K Q +E QR++ AE ++A AE + + + L A
Sbjct: 2434 RKQAEEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEA 2493
Query: 1075 PFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSP 1134
+ + EE + L+ + +++ S + +S
Sbjct: 2494 KLL---------------------QLKSEEMQTVQQEQLLQETQALQQSFLSEKDSLLQR 2532
Query: 1135 DNMSSASGLDMGKI------------EEMEKMLKEAHAEKNRLMESREREMELRRQALEE 1182
+ + ++ EE ++ ++ E+ RL+ S E + +A E
Sbjct: 2533 ERFIEQEKAKLEQLFQDEVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEG 2592
Query: 1183 ERRRREQVERRLQSESARRQQLVEKEVKMREK 1214
RR++E++++ Q + + L E+ ++RE+
Sbjct: 2593 VRRKQEELQQLEQQRRQQEELLAEENQRLREQ 2624
Score = 72.0 bits (175), Expect = 4e-12
Identities = 144/673 (21%), Positives = 276/673 (41%), Gaps = 81/673 (12%)
Query: 591 EYHRRQRQERLR-----EQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAA 645
E RR+ +ER++ E+E R + LE + L A+ A E E S + A
Sbjct: 2007 ERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQLQLA 2066
Query: 646 LALAGRR-PSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDA 704
A +R + A A +E Q L +++++ ++ L + E+ ++ E+A
Sbjct: 2067 QEAAQKRLQAEEKAHAFAVQQKE-----QELQQTLQQ-EQSVLDQLRGEAEAARRAAEEA 2120
Query: 705 PSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAR-EAEMERALLQGEREAER 763
++Q E E AQ VE+ + + E+Q Q A+ +A E+ + E+EA R
Sbjct: 2121 EEARVQAE-----REAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQEAAR 2175
Query: 764 ALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEER 823
Q EQ A+ Q Q A + ++K + + L + ++ ++L +L+ E + ++
Sbjct: 2176 RA-QAEQAALRQKQ----AADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEE-TDHQK 2229
Query: 824 ELAGQGLLRSKAELLRSIAKRKE------RLAILDSQAGQIRAQAVQESERLA-RDKNAS 876
L + L R KAE + +R + + + + +++A+ E+ L RDK+ +
Sbjct: 2230 NLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDKDNT 2289
Query: 877 LQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGT 936
+ LQ+E EK+ + L+ L E E L E+ +E M +
Sbjct: 2290 QRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAE-EDLAQQRALAEKMLKEKMQAVQE 2348
Query: 937 GP---AAASPHSSPPPLPAKASRQLQVYRSKMD---GEATSPLPRTRSGPLPSSSGSSSS 990
A A L + +R+LQ + +M E T RT S+
Sbjct: 2349 ATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMSAE 2408
Query: 991 SSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQ--QVIEEQ 1048
+ +L + S + A R A + + + +LA Q+K Q +E Q
Sbjct: 2409 AERLKLRVAEMSRAQARA----EEDAQRFRKQAEEIGEKLHRTELATQEKVTLVQTLEIQ 2464
Query: 1049 RRRL---AELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEG 1105
R++ AE ++A AE + + + L A + + EE
Sbjct: 2465 RQQSDHDAERLREAIAELEREKEKLQQEAKLL---------------------QLKSEEM 2503
Query: 1106 EHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRL 1165
+ L+ + +++ S + +S + ++ K + +E++ ++ A+ +L
Sbjct: 2504 QTVQQEQLLQETQALQQSFLSEKDSLLQRERF-----IEQEKAK-LEQLFQDEVAKAQQL 2557
Query: 1166 MESRERE---MELRRQAL----EEERRRREQVERRLQSESARRQQLVEKEVKMREKQFSQ 1218
E ++R+ ME RQ L EE RRR+ + E ++ + QQL ++ + E +
Sbjct: 2558 REEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQQEELLAEE 2617
Query: 1219 ARPLTRYLPIRKE 1231
+ L L + +E
Sbjct: 2618 NQRLREQLQLLEE 2630
Score = 68.2 bits (165), Expect = 5e-11
Identities = 156/694 (22%), Positives = 276/694 (39%), Gaps = 96/694 (13%)
Query: 596 QRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSR 655
Q+Q+R ++E+++L RQ E + A + A E L I E + L R
Sbjct: 1439 QQQKRSIQEELQQL-RQSSEAEIQAKARQAEA---AERSRL-RIEEEIRVVRLQLEATER 1493
Query: 656 GLAGASG-----RSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQ 710
GA G R+ E A +R ++ E ++ + + S Q E E A K +
Sbjct: 1494 QRGGAEGELQALRARAEEAEAQKR--QAQEEAERLRRQVQDESQRKRQAEVELASRVKAE 1551
Query: 711 GEVLALEEERAQVLGHVEQLKVRVKELEQQLQESA--REAEMERALLQGEREAERALLQK 768
E A E++RA L +E+L+++ +E E++L+++ R +++ AL +R AE L K
Sbjct: 1552 AEA-AREKQRA--LQALEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSK 1608
Query: 769 EQKAVDQ-------LQEKLVA---LETGIQKERDKEAEALETETKLFEDLEFQQLERES- 817
++ LQE+ VA L ++ ++AEA + +LE QL+
Sbjct: 1609 RASFAEKTAQLERSLQEEHVAVAQLREEAERRAQQQAEAERAREEAERELERWQLKANEA 1668
Query: 818 ---RVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKN 874
R++ E + L +++AE + A+R+ R + G+ QAV++ E ++
Sbjct: 1669 LRLRLQAEEVAQQKSLAQAEAEKQKEEAEREAR------RRGKAEEQAVRQRELAEQELE 1722
Query: 875 ASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTL--KEMEKLLLPAVDLEQWYQELMA 932
QL + ++ E+ L + L +E+ +L A Q QEL A
Sbjct: 1723 KQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKRQELEA 1782
Query: 933 GLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRT---RSGPLPSSSGSSS 989
L A + + SR +SK EA + R + L + + +
Sbjct: 1783 ELAKVRAEMEVLLASKARAEEESRSTSE-KSKQRLEAEAGRFRELAEEAARLRALAEEAK 1841
Query: 990 SSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQQVIEE-- 1047
QL+ R + +L + T +I K + A ++ +++ E+
Sbjct: 1842 RQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLAEDEA 1901
Query: 1048 -QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGE 1106
QRRRL E + A+ + + L A+ ++ R + EE
Sbjct: 1902 FQRRRLEEQAAQHKADIEERLAQLRKASDSELE-------RQKGLVEDTLRQRRQVEE-- 1952
Query: 1107 HAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIE-EMEKMLKEAHAEKN-R 1164
+ L+L++S + GK E E+E ++AE R
Sbjct: 1953 ---EILALKASFEKAAA----------------------GKAELELELGRIRSNAEDTLR 1987
Query: 1165 LMESREREMELRRQALEEERRRREQVERRLQ------SESARRQQLVEKEVKMREKQFSQ 1218
E E E +RQ EE RRR + E R+Q E+AR+++ +EV+ + + +
Sbjct: 1988 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEE 2047
Query: 1219 ARPL--------TRYLPIRKEDFDLKTHIESSGH 1244
AR L R L + +E + E H
Sbjct: 2048 ARRLRERAEQESARQLQLAQEAAQKRLQAEEKAH 2081
Score = 61.6 bits (148), Expect = 5e-09
Identities = 165/730 (22%), Positives = 285/730 (39%), Gaps = 129/730 (17%)
Query: 584 DNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEAT 643
+ E+ L E R + +ERL E E LE+QR L ++A EA EL +
Sbjct: 1372 EEEERLAEQQRAEERERLAEVEAA-LEKQRQ---LAEAHAQAKAQAEREAKEL----QQR 1423
Query: 644 AALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHED 703
+ R + A RS +E Q+L +S E + ++ ++ S + E+
Sbjct: 1424 MQEEVVRREEAAVDAQQQKRSIQEE---LQQLRQSSEAEIQAKARQAEAAERSRLRIEEE 1480
Query: 704 APSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGERE--- 760
+LQ E A E +R G ++ L+ R +E E Q +++ EAE R +Q E +
Sbjct: 1481 IRVVRLQLE--ATERQRGGAEGELQALRARAEEAEAQKRQAQEEAERLRRQVQDESQRKR 1538
Query: 761 -----------AERALLQKEQKAVDQLQEKLVALETGIQKERDKEAE-------ALETET 802
AE +++Q+A+ L+E + E ++ R E E ALET
Sbjct: 1539 QAEVELASRVKAEAEAAREKQRALQALEELRLQAEEAERRLRQAEVERARQVQVALETAQ 1598
Query: 803 KLFEDLEFQ-----------QLERE--------SRVEEERELAGQGLLRSKAELLRSIAK 843
+ E E Q QLER +++ EE E Q +++AE R A+
Sbjct: 1599 RSAE-AELQSKRASFAEKTAQLERSLQEEHVAVAQLREEAERRAQ--QQAEAERAREEAE 1655
Query: 844 RK-ERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERR--------- 893
R+ ER + ++A ++R QA E +A+ K+ + +K+KE+ RR
Sbjct: 1656 RELERWQLKANEALRLRLQA----EEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAV 1711
Query: 894 ------YHSLTGGRPFPKTTS--TLKEMEKLLLPAVDLEQWYQ------ELMAGLGTGPA 939
L R + T+ L ++L+ + EQ Q E +A L A
Sbjct: 1712 RQRELAEQELEKQRQLAEGTAQQRLAAEQELIRLRAETEQGEQQRQLLEEELARLQREAA 1771
Query: 940 AASPHSSPPPLP-AKASRQLQVY-----RSKMDGEATSPLPRTR--------------SG 979
AA+ AK +++V R++ + +TS + R +
Sbjct: 1772 AATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAA 1831
Query: 980 PLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQ 1039
L + + + QL+ R + +L + T +I K + A +
Sbjct: 1832 RLRALAEEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENE 1891
Query: 1040 KGQQVIEE---QRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLP 1096
+ +++ E+ QRRRL E + A+ + + L A+ L L
Sbjct: 1892 RLRRLAEDEAFQRRRLEEQAAQHKADIEERLAQLRKASD--------SELERQKGLVEDT 1943
Query: 1097 AGRERGEEGEHAYDTLSLE--SSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKM 1154
+ R E E S E ++ E + G + + D + S ++ + +
Sbjct: 1944 LRQRRQVEEEILALKASFEKAAAGKAELELELGRIRSNAEDTLRSKEQAELEAARQRQLA 2003
Query: 1155 LKEAHAEK---NRLMESREREMELRRQ---ALEEERRRREQVE------RRLQSESARRQ 1202
+E + R+ +S E E RQ ALEE R + +VE R + ESAR+
Sbjct: 2004 AEEERRRREAEERVQKSLAAEEEAARQRKAALEEVERLKAKVEEARRLRERAEQESARQL 2063
Query: 1203 QLVEKEVKMR 1212
QL ++ + R
Sbjct: 2064 QLAQEAAQKR 2073
Score = 57.0 bits (136), Expect = 1e-07
Identities = 109/483 (22%), Positives = 190/483 (39%), Gaps = 82/483 (16%)
Query: 554 QSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQR 613
Q V+++L++ L++ T +KN + E RQR + E R++ +
Sbjct: 2207 QKAQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEE 2266
Query: 614 LETILNLCAEYSRA------DGGP-----EAGELPSIGEATAALALAGRRPSRGLAGASG 662
L + +RA D EA ++ + E A L++A + +R A
Sbjct: 2267 LSKLKARIEAENRALILRDKDNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEE 2326
Query: 663 RSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQ 722
+++ +A + L E M+ E + + Q+E + +LQ + +E+ AQ
Sbjct: 2327 DLAQQRALAEKMLKEKMQAVQEATRLKAEAELLQQQKELAQEQARRLQED----KEQMAQ 2382
Query: 723 VLGHVEQLKVRVKELEQQ--LQESA-------REAEMERALLQGEREAERALLQKEQKAV 773
L Q R E E+Q L+ SA R AEM RA + E +A+R +K
Sbjct: 2383 QLAEETQGFQRTLEAERQRQLEMSAEAERLKLRVAEMSRAQARAEEDAQRF-----RKQA 2437
Query: 774 DQLQEKLVALETGIQK---------------------------ERDKEAEALETETKLFE 806
+++ EKL E Q+ E ++E E L+ E KL +
Sbjct: 2438 EEIGEKLHRTELATQEKVTLVQTLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ 2497
Query: 807 --DLEFQQLERESRVEEERELAGQGLLRSKAELL---RSIAKRKERLAILDSQAGQIRAQ 861
E Q +++E ++E + L Q L K LL R I + K +L Q+
Sbjct: 2498 LKSEEMQTVQQEQLLQETQALQ-QSFLSEKDSLLQRERFIEQEKAKLE-------QLFQD 2549
Query: 862 AVQESERLARDKNASLQLLQKEKEKLTV----LERRYHSLTGG-----RPFPKTTSTLKE 912
V ++++L ++ Q +++E+++L RR H G + ++
Sbjct: 2550 EVAKAQQLREEQQRQQQQMEQERQRLVASMEEARRRQHEAEEGVRRKQEELQQLEQQRRQ 2609
Query: 913 MEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSP-PPLPAKASRQLQVYRSKMDGEATS 971
E+LL + Q +E + L AA HS A++ L R +DG A
Sbjct: 2610 QEELL---AEENQRLREQLQLLEEQHRAALAHSEEVTASQVAATKTLPNGRDALDGPAAE 2666
Query: 972 PLP 974
P
Sbjct: 2667 AEP 2669
Score = 56.6 bits (135), Expect = 2e-07
Identities = 140/678 (20%), Positives = 259/678 (38%), Gaps = 97/678 (14%)
Query: 574 ERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEA 633
ER + + SD+E +RQ+ L E + R RQ E IL L A + +A G
Sbjct: 1920 ERLAQLRKASDSE--------LERQKGLVEDTL-RQRRQVEEEILALKASFEKAAAGKAE 1970
Query: 634 GELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSS 693
EL GR S + E A QR + E
Sbjct: 1971 LELE-----------LGRIRSNAEDTLRSKEQAELEAARQRQLAAEE------------- 2006
Query: 694 TESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERA 753
E ++E E+ L E A + +A L VE+LK +V+E ++L+E A
Sbjct: 2007 -ERRRREAEERVQKSLAAEEEAARQRKA-ALEEVERLKAKVEEA-RRLRERA-------- 2055
Query: 754 LLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQ-- 811
E+E+ R L ++ A +LQ + A +Q++ + + L+ E + + L +
Sbjct: 2056 ----EQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQQEQSVLDQLRGEAE 2111
Query: 812 ------QLERESRVEEERELAGQGLLRSKAELLRSIAKRK-ERLAILDSQAGQIRAQAVQ 864
+ E+RV+ ERE A +AE L+ A+ + + A + A ++R +A Q
Sbjct: 2112 AARRAAEEAEEARVQAEREAAQSRRQVEEAERLKQSAEEQAQARAQAQAAAEKLRKEAEQ 2171
Query: 865 ESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVD-- 922
E+ R A+ + A+L+ +++ E H + + +E+ L L +
Sbjct: 2172 EAARRAQAEQAALR-----QKQAADAEMEKHKKFAEQTLRQKAQVEQELTTLRLQLEETD 2226
Query: 923 -----LEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTR 977
L++ Q L A S +L +++++ E + + R +
Sbjct: 2227 HQKNLLDEELQRLKAEATEAARQRSQVEEELFSVRVQMEELSKLKARIEAENRALILRDK 2286
Query: 978 SGPLPSSSGSSSSSSQLSVATLGRSPSPKSA----------LLTQNGTGS--LPRNLAAT 1025
+ Q++ S + + A L Q L + A
Sbjct: 2287 DNTQRFLQEEAEKMKQVAEEAARLSVAAQEAARLRQLAEEDLAQQRALAEKMLKEKMQAV 2346
Query: 1026 LQDIETKRQLALQQKGQQVIEEQRRRLAE----LKQKAAAEAQCQWDALHGAAPFPAGPS 1081
+ K + L Q+ +++ +EQ RRL E + Q+ A E Q L S
Sbjct: 2347 QEATRLKAEAELLQQQKELAQEQARRLQEDKEQMAQQLAEETQGFQRTLEAERQRQLEMS 2406
Query: 1082 GFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSAS 1141
+ + + + R EE + + E + + + + + ++
Sbjct: 2407 AEAERLKLRVA-EMSRAQARAEEDAQRFRKQAEEIGEKLHRT------ELATQEKVTLVQ 2459
Query: 1142 GLDMGK--IEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESA 1199
L++ + + + L+EA AE R E ++E +L + L+ E + Q E+ LQ A
Sbjct: 2460 TLEIQRQQSDHDAERLREAIAELEREKEKLQQEAKLLQ--LKSEEMQTVQQEQLLQETQA 2517
Query: 1200 RRQQ-LVEKEVKMREKQF 1216
+Q L EK+ ++ ++F
Sbjct: 2518 LQQSFLSEKDSLLQRERF 2535
Score = 56.2 bits (134), Expect = 2e-07
Identities = 155/719 (21%), Positives = 275/719 (38%), Gaps = 122/719 (16%)
Query: 576 KNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGE 635
K + E S E+ + R+ ER +Q+ E ER R E L +A+ EA
Sbjct: 1615 KTAQLERSLQEEHVAVAQLREEAERRAQQQAEA-ERAREEAERELERWQLKAN---EALR 1670
Query: 636 LPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTE 695
L E A + + + R + G A ++ E +++E L+++ E
Sbjct: 1671 LRLQAEEVAQQKSLAQAEAEKQKEEAEREARRRGKAEEQAVRQRELAEQE-LEKQRQLAE 1729
Query: 696 STQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREA------- 748
T Q+ LA E+E ++ EQ + + + LE++L REA
Sbjct: 1730 GTAQQR------------LAAEQELIRLRAETEQGEQQRQLLEEELARLQREAAAATQKR 1777
Query: 749 ---EMERALLQGERE---AERALLQKEQKAVDQLQEKLVALETGIQKERDKEA---EALE 799
E E A ++ E E A +A ++E ++ + ++ + E G +E +EA AL
Sbjct: 1778 QELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAEAGRFRELAEEAARLRALA 1837
Query: 800 TETK-----LFEDLEFQQLERESRVEEERELAGQGL-LRSKAEL-LRSIAKRKERLAILD 852
E K ED Q+ E E + E+ G+ L+++AE+ L+ ERL L
Sbjct: 1838 EEAKRQRQLAEEDAARQRAEAERVLAEKLAAIGEATRLKTEAEIALKEKEAENERLRRLA 1897
Query: 853 S----QAGQIRAQAVQE----SERLARDKNASLQLLQKEKEKL--TVLERRYHSLTGGRP 902
Q ++ QA Q ERLA+ + AS L+++K + T+ +RR
Sbjct: 1898 EDEAFQRRRLEEQAAQHKADIEERLAQLRKASDSELERQKGLVEDTLRQRR--------- 1948
Query: 903 FPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYR 962
+ E++L E+ AAA L S R
Sbjct: 1949 --------QVEEEILALKASFEK-------------AAAGKAELELELGRIRSNAEDTLR 1987
Query: 963 SKMDGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNL 1022
SK E + R + + Q S+A + + A L + L
Sbjct: 1988 SKEQAELEAARQRQLAAEEERRRREAEERVQKSLAAEEEAARQRKAALEE------VERL 2041
Query: 1023 AATLQDIETKRQLALQQKGQQV----IEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPA 1078
A +++ R+ A Q+ +Q+ Q+R AE K A A Q + +
Sbjct: 2042 KAKVEEARRLRERAEQESARQLQLAQEAAQKRLQAEEKAHAFAVQQKEQELQQTLQ---- 2097
Query: 1079 GPSGFPPLMHHSILHHL----PAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSP 1134
S+L L A R EE E A E++ S + S
Sbjct: 2098 --------QEQSVLDQLRGEAEAARRAAEEAEEARVQAEREAAQS-RRQVEEAERLKQSA 2148
Query: 1135 DNMSSASGLDMGKIEEMEK-----MLKEAHAEKNRLMESR--EREMELRRQALEEERRRR 1187
+ + A E++ K + A AE+ L + + + EME ++ E+ R++
Sbjct: 2149 EEQAQARAQAQAAAEKLRKEAEQEAARRAQAEQAALRQKQAADAEMEKHKKFAEQTLRQK 2208
Query: 1188 EQVERRLQS------ESARRQQLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIE 1240
QVE+ L + E+ ++ L+++E++ + + ++A + + +E F ++ +E
Sbjct: 2209 AQVEQELTTLRLQLEETDHQKNLLDEELQRLKAEATEA--ARQRSQVEEELFSVRVQME 2265
Score = 50.1 bits (118), Expect = 1e-05
Identities = 115/550 (20%), Positives = 214/550 (38%), Gaps = 75/550 (13%)
Query: 695 ESTQQEH--EDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMER 752
E QQ H D + + V L E VL + + +++L +QL+ A+
Sbjct: 1188 ERLQQRHGERDVEVERWRERVAQLLERWQAVLAQTDVRQRELEQLGRQLRYYRESADPLG 1247
Query: 753 ALLQGEREAERAL----LQKEQKAVDQLQEKLVALETGIQKERDKEAEA---LETETKLF 805
A LQ R + + L Q +QL+++ LE I++ +K E +
Sbjct: 1248 AWLQDARRRQEQIQAMPLADSQAVREQLRQEQALLEE-IERHGEKVEECQRFAKQYINAI 1306
Query: 806 EDLEFQQLERESRVEEERELAGQGLLRSKAELLRS----IAKRKERLAILDSQAGQIRAQ 861
+D E Q + ++++E A + ++S +E + + L L SQ + ++
Sbjct: 1307 KDYELQLVTYKAQLEPVASPAKKPKVQSGSESVIQEYVDLRTHYSELTTLTSQYIKFISE 1366
Query: 862 AV---QESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLL 918
+ +E ERLA + A +E+E+L +E +L R + + K +
Sbjct: 1367 TLRRMEEEERLAEQQRA------EERERLAEVEA---ALEKQRQLAEAHAQAKAQAER-- 1415
Query: 919 PAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRS 978
A +L+Q QE + A +LQ R + E + + +
Sbjct: 1416 EAKELQQRMQEEVVRREEAAVDAQQQKR------SIQEELQQLRQSSEAEIQAKARQAEA 1469
Query: 979 GPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQ 1038
+ ++ V L + + + G + L A ++ E +++ A +
Sbjct: 1470 ----AERSRLRIEEEIRVVRLQLEATERQ----RGGAEGELQALRARAEEAEAQKRQAQE 1521
Query: 1039 Q----KGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHH 1094
+ + Q E QR+R AE++ + +A+ + A L
Sbjct: 1522 EAERLRRQVQDESQRKRQAEVELASRVKAEAEAAREKQRA-----------------LQA 1564
Query: 1095 LPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEKM 1154
L R + EE E +E + ++ ++ T SA + AS + K ++E+
Sbjct: 1565 LEELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE--KTAQLERS 1622
Query: 1155 LKEAHAEKNRLMESREREMELRRQALEEERRRREQVER-----RLQSESARRQQLVEKEV 1209
L+E H +L E ER R Q E R RE+ ER +L++ A R +L +EV
Sbjct: 1623 LQEEHVAVAQLREEAER----RAQQQAEAERAREEAERELERWQLKANEALRLRLQAEEV 1678
Query: 1210 KMREKQFSQA 1219
++K +QA
Sbjct: 1679 -AQQKSLAQA 1687
Score = 35.8 bits (81), Expect = 0.29
Identities = 22/78 (28%), Positives = 40/78 (51%), Gaps = 4/78 (5%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVE 1206
++EE E++ ++ AE+ + E +E +RQ E + + Q ER E+ QQ ++
Sbjct: 1370 RMEEEERLAEQQRAEERERLAEVEAALEKQRQLAEAHAQAKAQAER----EAKELQQRMQ 1425
Query: 1207 KEVKMREKQFSQARPLTR 1224
+EV RE+ A+ R
Sbjct: 1426 EEVVRREEAAVDAQQQKR 1443
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 71.6 bits (174), Expect = 5e-12
Identities = 90/358 (25%), Positives = 127/358 (35%), Gaps = 39/358 (10%)
Query: 146 PAGGRAPGPPYSPVPAESESLVNGNHTPQTATRGPSACASHSSLVSSIEKDLQEIMDSLV 205
P+ AP PP + P+ L H T + + L + K +
Sbjct: 1097 PSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATP 1156
Query: 206 LEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSY-ENTSPAFSPLSSPASS 264
G P +P +P A +PP+ G ++ S T+PA +P P+
Sbjct: 1157 PSPKGGLATPPPKGAPTTPAA-------TPPSPKGGLATPSPKGAPTTPAATP---PSPK 1206
Query: 265 GSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPSGARSESPRLSRKGGHERPPS 324
G A+ SP G P+ P P LA P+ P+ + P S KGG PP
Sbjct: 1207 GGLATPSPKGAPTTPAATPPSPKGG----LATPSPKGAPTTPAATPP--SPKGGPATPPP 1260
Query: 325 PGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVAISLSEY------PASGALSQPTSI 378
G PAAT + P G P V S P GA + P +
Sbjct: 1261 KGA----PTPPAATPPSLKGGLATPPHKGAPNPAVVTPPSPKGGPATSPPKGAPTPPAAT 1316
Query: 379 PGSPKFQPPVPAPRNKIGTLQDRPPSPFREP------PGSERVLTTSPSRQLVGRTFSDG 432
P SPK P P P+ PPSP P P S+ TT S++ G T
Sbjct: 1317 PPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKE--GPTPPAA 1374
Query: 433 LATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPTRTTPDPKLNREVAESP 490
+ P +P +RG +P + A+ PL + P + RE A +P
Sbjct: 1375 TPSHKGGPAMTPPSPKRG----PAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATP 1428
Score = 61.6 bits (148), Expect = 5e-09
Identities = 115/458 (25%), Positives = 162/458 (35%), Gaps = 84/458 (18%)
Query: 145 IPAGGRAPGPPYSPVPAESESLVNGNHTPQTA--TRGPSACA---SHSSLVSSIEKDLQE 199
IP +P P + P ++ + +HT A P C S +S +S + L
Sbjct: 730 IPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTY 789
Query: 200 IMDS------LVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSY--ENT 251
+ DS V + K + P +P+ N LS P SP V +S+ EN+
Sbjct: 790 LADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGN-----LSSPVSP----VEASFLPENS 840
Query: 252 SPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPA----------RSSSYHLALQ---- 297
SPA++ S SP G +V PL P S +L
Sbjct: 841 LSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPFPKEGP 900
Query: 298 ----PPQSRPSGARSESPRLSRKGGHER--PPSPGLRGLLTDSPAATVLAEARRATESPR 351
P Q+ S SP+ +R + P SP +G T A + AT SP+
Sbjct: 901 ATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPK 960
Query: 352 LGGQLPVVAI-SLSEYPAS----GALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPF 406
P S PA+ GA + P + P SPK P P+P+ P P
Sbjct: 961 WAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPSPKGGPATPSPKG-------APTPPA 1013
Query: 407 REPPGSERVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSR 466
PP SP F G +T P SP +G + LP +P+
Sbjct: 1014 VTPP--------SPKGSPAATPFPKGASTPPAATPPSP----KGSPAATPLPKGAPT--- 1058
Query: 467 RALSPLPTRTTPDPK---LNREVAESPRPRRWAAHGASPEDFSLTLGARGR----RTRSP 519
P T P PK + +P P AA SP+ T +G P
Sbjct: 1059 -----TPAATLPSPKGGPATPSLKGAPTPP--AATPPSPKGGPATPSPKGAPMPPAATPP 1111
Query: 520 SPTLGESLAPHKGS-FSGRLSPAYSLGSLTGASPCQSP 556
SP G + PHKG+ + +P G L P +P
Sbjct: 1112 SPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAP 1149
Score = 58.5 bits (140), Expect = 4e-08
Identities = 80/338 (23%), Positives = 113/338 (33%), Gaps = 51/338 (15%)
Query: 209 PGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSP-------LSSP 261
P P A +P SP +P + G + S T PA +P ++ P
Sbjct: 1328 PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGGPAMTPP 1387
Query: 262 ASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLA-----------LQPPQSRPSGARSES 310
+ A SP G P+V PL P ++ + + L PP P +
Sbjct: 1388 SPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAP 1447
Query: 311 PRLSRKGGHERPPSPG---LRGLLTDSPAATVLAEARRATESPRLGGQLPVVAISLSEYP 367
+ KGG P S G L + SP + + SP+ P
Sbjct: 1448 ATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPA--------- 1498
Query: 368 ASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSPSRQLVGR 427
GA + P IP SPK P P+ R P +P + T +P L+
Sbjct: 1499 PMGAPTLPAVIPSSPKEVPATPSSRRD-------PIAPTATLLSKKTPATLAPKEALIPP 1551
Query: 428 TFSDGLATRTLQPPESPRLGRRGLDSMRELPP-LSPSLSRRALSPL-----PTRTTPDPK 481
+ +T P PP ++PS + A SP P T+P PK
Sbjct: 1552 AMTVPSPKKTPAIPTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPK 1611
Query: 482 LNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSP 519
E+P P A SPE T +G T P
Sbjct: 1612 ------EAPTPP--AVTPPSPEKGPATPAPKGTPTSPP 1641
Score = 43.9 bits (102), Expect = 0.001
Identities = 67/271 (24%), Positives = 95/271 (35%), Gaps = 42/271 (15%)
Query: 146 PAGGRAPGPPYSPVPAESESLVNGNHTPQTATRGPSACASHSSLVSSIEKDLQEIMDSLV 205
PA G P SP P SL + +P + T A +S +K + + LV
Sbjct: 1628 PATPAPKGTPTSP-PVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLV 1686
Query: 206 LEEPGAAGKKPAATSPL--SPMANGGRYLLSPPTSPGAMSV-GSSYENTSPAFSPL---- 258
P + P T+P P SPP P + GS ++ A +PL
Sbjct: 1687 APAPEST---PIITAPTRKGPQTKKSS-ATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQ 1742
Query: 259 --SSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPSGARSESPRLSRK 316
SS + G ASHSP G P P ++++ L P+S A
Sbjct: 1743 KDSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSA---------- 1792
Query: 317 GGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVAISLSEYPASGALSQPT 376
PSP + L SP T+ + + SP L + P ++ ++ L P
Sbjct: 1793 -----APSPPVSLPLAPSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPE 1847
Query: 377 SIPGSPKFQP-------------PVPAPRNK 394
I G FQ PVP P K
Sbjct: 1848 PISGGVPFQSVLVNMPTPKSAGIPVPTPSAK 1878
Score = 38.5 bits (88), Expect = 0.045
Identities = 148/664 (22%), Positives = 240/664 (36%), Gaps = 142/664 (21%)
Query: 127 STFLRFNHPAEAKWMKSMIPAGGRAPGPPYSP-VPAESESLVNGNHTPQTATRGPSACAS 185
+T L PA +++IP P P +P +P E+ AT +S
Sbjct: 1531 ATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEA---------PATPSSKEASS 1581
Query: 186 HSSLVSSIEKDLQEIMDSLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVG 245
++ S K + L+ PA TSP SP +P
Sbjct: 1582 PPAVTPSTYKGAPSPKELLI---------PPAVTSP------------SPKEAP------ 1614
Query: 246 SSYENTSPAFSPLSSPASSGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPSG 305
T PA +P P+ A+ +P G P+ PP+ P SS + P S
Sbjct: 1615 -----TPPAVTP---PSPEKGPATPAPKGT---PTSPPVTP---SSLKDSPTSPASVTCK 1660
Query: 306 ARSESPRLSRKGGHERPPSPGLRGLLTDSPAAT--VLAEARRATESPRLGGQLPVVAISL 363
+ P+ S+ ++ P+ L+ +P +T + A R+ ++ + P +
Sbjct: 1661 MGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTRKGPQTKKSSATSPPICPDP 1720
Query: 364 SEYPAS-GALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSPSR 422
S S G LS T P P +P ++ T + + S P G + S
Sbjct: 1721 SAKNGSKGPLS--TVAPA-----PLLPVQKDSSKTAKGKDAS--HSPKGPLAPPESKAST 1771
Query: 423 QLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPTRTTPDPKL 482
L F + L PES + S PP+S L A SP+PT P
Sbjct: 1772 PLTAAAFE-----KVLPKPESASV------SAAPSPPVSLPL---APSPVPTL----PPK 1813
Query: 483 NREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGSFSGRLSPAY 542
+ + SP G SPS + LAP + L P
Sbjct: 1814 QQFLPSSP----------------------GLVLESPS----KPLAP---ADEDELLPLI 1844
Query: 543 SLGSLTGASPCQSPCVQR--------KLSSGDLRVPVTRERKNSITEISDNEDDLLEYHR 594
++G P QS V + + + PVT+ K S TE SD+++ + E
Sbjct: 1845 PPEPISGGVPFQSVLVNMPTPKSAGIPVPTPSAKQPVTKNNKGSGTE-SDSDESVPE--- 1900
Query: 595 RQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPS 654
L EQ+ + Q+ + L AE + +A + S +A A++ G R
Sbjct: 1901 ------LEEQDSTQATTQQAQ--LAAAAEIDE-EPVSKAKQSRSEKKARKAMSKLGLRQV 1951
Query: 655 RGLAGASGRSSEE-PGVATQRLWESMERSDEENLKEECSSTESTQQ-EHEDAPSTKLQGE 712
G+ + R S+ V T+ SD + E + +QQ + A K+QGE
Sbjct: 1952 TGVTRVTIRKSKNILFVITKPDVYKSPASDTYIVFGEAKIEDLSQQAQLAAAEKFKVQGE 2011
Query: 713 VLALEEERAQV--------LGHVEQLKVRVKELEQQL-QESAREAEMERALLQGEREAER 763
++ +E Q V++ V VK++E + Q + A+ RAL +
Sbjct: 2012 AVSNIQENTQTPTVQEESEEEEVDETGVEVKDIELVMSQANVSRAKAVRALKNNSNDIVN 2071
Query: 764 ALLQ 767
A+++
Sbjct: 2072 AIME 2075
Score = 31.2 bits (69), Expect = 7.2
Identities = 33/103 (32%), Positives = 40/103 (38%), Gaps = 11/103 (10%)
Query: 933 GLGTGPAAA--SPHSSPP--PLPAKA-SRQLQVYRSKMDGEAT-----SPLPRTRSGPLP 982
G T PAA SP SP PLP A + S G AT +P P + P P
Sbjct: 1031 GASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKGAPTPPAATPPSP 1090
Query: 983 SSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAAT 1025
++ S + PSPK L T G+ P AAT
Sbjct: 1091 KGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGA-PTTPAAT 1132
>gi|145312241 differentially expressed in FDCP 6 homolog [Homo
sapiens]
Length = 631
Score = 70.9 bits (172), Expect = 8e-12
Identities = 84/335 (25%), Positives = 145/335 (43%), Gaps = 44/335 (13%)
Query: 641 EATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEE--------CS 692
E TAA+ +A R A G++S + +R + +R KEE
Sbjct: 302 EWTAAIQMAIRLQ------AEGKTSLHKDLKQKRREQREQRERRRAAKEEELLRLQQLQE 355
Query: 693 STESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMER 752
E QE E + Q E L EEE E+ + + +EL+Q L+ REAE R
Sbjct: 356 EKERKLQELELLQEAQRQAERLLQEEE--------ERRRSQHRELQQALEGQLREAEQAR 407
Query: 753 ALLQGE---REAERALLQKEQKAVDQLQEKL-VALETGIQKERDKEAEALETETKLFEDL 808
A +Q E +E E A ++ K ++++Q++L AL+ ++ RD+E+ + +T+L E+
Sbjct: 408 ASMQAEMELKEEEAARQRQRIKELEEMQQRLQEALQLEVKARRDEESVRI-AQTRLLEE- 465
Query: 809 EFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESER 868
E ++L++ +++EE+E + + K EL + +A++ L Q ++R + E
Sbjct: 466 EEEKLKQLMQLKEEQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQRADED 525
Query: 869 LARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVD-----L 923
+ + Q K + R H + G P T+S+ + LL D L
Sbjct: 526 VEAAQRKLRQASTNVKHWNVQMNRLMHPIEPGDKRPVTSSSFSGFQPPLLAHRDSSLKRL 585
Query: 924 EQW-----------YQELMAGLGTGPAAASPHSSP 947
+W E L G A +P S+P
Sbjct: 586 TRWGSQGNRTPSPNSNEQQKSLNGGDEAPAPASTP 620
Score = 39.7 bits (91), Expect = 0.020
Identities = 52/241 (21%), Positives = 100/241 (41%), Gaps = 33/241 (13%)
Query: 566 DLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYS 625
DL+ +R+ + E++LL + Q ++ + QE+E L+ + + L E
Sbjct: 324 DLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEE 383
Query: 626 RADGGPEAGELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEE 685
R R R L A E A + ME +EE
Sbjct: 384 RR-----------------------RSQHRELQQALEGQLREAEQARASMQAEMELKEEE 420
Query: 686 --NLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQ- 742
++ E QQ ++A LQ EV A +E + + L+ ++L+Q +Q
Sbjct: 421 AARQRQRIKELEEMQQRLQEA----LQLEVKARRDEESVRIAQTRLLEEEEEKLKQLMQL 476
Query: 743 ESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETET 802
+ +E +ERA Q E+E + + ++ +++ Q Q++L + Q+ D++ EA + +
Sbjct: 477 KEEQERYIERA--QQEKEELQQEMAQQSRSLQQAQQQLEEVRQNRQR-ADEDVEAAQRKL 533
Query: 803 K 803
+
Sbjct: 534 R 534
Score = 37.4 bits (85), Expect = 0.10
Identities = 26/91 (28%), Positives = 43/91 (47%), Gaps = 7/91 (7%)
Query: 1148 IEEMEKMLKEAHAEKNRLMESREREMELRRQAL-------EEERRRREQVERRLQSESAR 1200
++E E+ + H E + +E + RE E R ++ EEE R+ Q + L+ R
Sbjct: 378 LQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKEEEAARQRQRIKELEEMQQR 437
Query: 1201 RQQLVEKEVKMREKQFSQARPLTRYLPIRKE 1231
Q+ ++ EVK R + S TR L +E
Sbjct: 438 LQEALQLEVKARRDEESVRIAQTRLLEEEEE 468
Score = 35.4 bits (80), Expect = 0.38
Identities = 26/86 (30%), Positives = 45/86 (52%), Gaps = 11/86 (12%)
Query: 1147 KIEEMEKMLKEAHAEKNRLMESREREMELR----RQALEEERRRRE------QVERRLQS 1196
K++E+E +L+EA + RL++ E + +QALE + R E Q E L+
Sbjct: 360 KLQELE-LLQEAQRQAERLLQEEEERRRSQHRELQQALEGQLREAEQARASMQAEMELKE 418
Query: 1197 ESARRQQLVEKEVKMREKQFSQARPL 1222
E A RQ+ KE++ +++ +A L
Sbjct: 419 EEAARQRQRIKELEEMQQRLQEALQL 444
Score = 35.0 bits (79), Expect = 0.50
Identities = 40/194 (20%), Positives = 80/194 (41%), Gaps = 18/194 (9%)
Query: 1026 LQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPP 1085
LQ++E ++ Q + EE+RRR + + A E Q L A A
Sbjct: 361 LQELELLQEAQRQAERLLQEEEERRRSQHRELQQALEGQ-----LREAEQARASMQAEME 415
Query: 1086 LMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDM 1145
L +E E + + L LE + +++ A +
Sbjct: 416 LKEEEAARQRQRIKELEEMQQRLQEALQLEVKARRD------------EESVRIAQTRLL 463
Query: 1146 GKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLV 1205
+ EE K L + E+ R +E ++E E +Q + ++ R +Q +++L+ E + +Q
Sbjct: 464 EEEEEKLKQLMQLKEEQERYIERAQQEKEELQQEMAQQSRSLQQAQQQLE-EVRQNRQRA 522
Query: 1206 EKEVKMREKQFSQA 1219
+++V+ +++ QA
Sbjct: 523 DEDVEAAQRKLRQA 536
Score = 32.0 bits (71), Expect = 4.2
Identities = 28/107 (26%), Positives = 41/107 (38%), Gaps = 20/107 (18%)
Query: 1260 RGYLVKMGGKIKSWKKRWFVFDRLKRTLSYYVDKHETKLK-GVIYFQAIEEVYYDHLRSA 1318
+GYL K G ++W +RWF +L+ + Y E K K G+I A
Sbjct: 220 QGYLWKRGHLRRNWAERWF---QLQPSCLCYFGSEECKEKRGIIPLDA------------ 264
Query: 1319 AKKRFFRFTMVTESPNPALTFCVKTHDRLYYMVAPSAEAMRIWMDVI 1365
++ + FCVKT +R Y M A + W I
Sbjct: 265 ----HCCVEVLPDRDGKRCMFCVKTANRTYEMSASDTRQRQEWTAAI 307
Score = 32.0 bits (71), Expect = 4.2
Identities = 28/78 (35%), Positives = 35/78 (44%), Gaps = 14/78 (17%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQA----LEEERRRREQVERRLQ--------- 1195
EE L++ EK R ++ E E +RQA EEE RRR Q R LQ
Sbjct: 344 EEELLRLQQLQEEKERKLQELELLQEAQRQAERLLQEEEERRRSQ-HRELQQALEGQLRE 402
Query: 1196 SESARRQQLVEKEVKMRE 1213
+E AR E E+K E
Sbjct: 403 AEQARASMQAEMELKEEE 420
Score = 30.8 bits (68), Expect = 9.4
Identities = 15/67 (22%), Positives = 39/67 (58%), Gaps = 1/67 (1%)
Query: 1149 EEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEKE 1208
+++++ +E ++ R ++E E+ +Q EE+ R+ +++E LQ + ++L+++E
Sbjct: 323 KDLKQKRREQREQRERRRAAKEEELLRLQQLQEEKERKLQELE-LLQEAQRQAERLLQEE 381
Query: 1209 VKMREKQ 1215
+ R Q
Sbjct: 382 EERRRSQ 388
>gi|153791497 ciliary rootlet coiled-coil [Homo sapiens]
Length = 2017
Score = 70.9 bits (172), Expect = 8e-12
Identities = 154/655 (23%), Positives = 265/655 (40%), Gaps = 90/655 (13%)
Query: 588 DLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALA 647
D+L+ + + E L + E R+E + T L E S D +L ++ E+ A
Sbjct: 697 DMLQAEKAEVAEALTKAEAGRVELELSMTKLR-AEEASLQDS---LSKLSALNESLAQDK 752
Query: 648 LAGRR-------PSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECS--STESTQ 698
L R L G ++ +E VA E ER +E L++E + E +
Sbjct: 753 LDLNRLVAQLEEEKSALQGRQRQAEQEATVAR----EEQERLEELRLEQEVARQGLEGSL 808
Query: 699 QEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGE 758
+ E A L+ ++ L ER+Q+ + QL ++ EQ+L+++ REA+ + L
Sbjct: 809 RVAEQAQEA-LEQQLPTLRHERSQLQEQLAQLSRQLSGREQELEQARREAQRQVEAL--- 864
Query: 759 REAERALLQKEQKAVDQ--LQEKLVALETGIQKERDKEAEALETETKLFEDLEFQ---QL 813
ERA +KE A + L +LVA E + +EA L E + E F+ QL
Sbjct: 865 ---ERAAREKEALAKEHAGLAVQLVAAERE-GRTLSEEATRLRLEKEALEGSLFEVQRQL 920
Query: 814 ERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAG---QIRAQAVQESERLA 870
+ E+ E GQ LL +K L +A ++++ +A ++ AQ + ++ER A
Sbjct: 921 AQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREA 980
Query: 871 ----RDKNAS----LQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVD 922
R++ A+ LQ LQ+EK E + L R + S L+ ++ LL ++
Sbjct: 981 QASLREQRAAHEEDLQRLQREK------EAAWRELEAER--AQLQSQLQREQEELLARLE 1032
Query: 923 LEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRTRSGPLP 982
E+ +EL + AA L A++ +Q + S + E T+
Sbjct: 1033 AEK--EELSEEI----AALQQERDEGLLLAESEKQQAL--SLKESEKTA----------- 1073
Query: 983 SSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLALQQKGQ 1042
S + L+ +L + A Q S L + L+D+ +R+ A Q
Sbjct: 1074 LSEKLMGTRHSLATISLEMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQ 1133
Query: 1043 QV--IEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRE 1100
+V ++EQ R L + + EA+ L G + +L RE
Sbjct: 1134 EVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDARDG-------LRRELLEAQRKLRE 1186
Query: 1101 RGEEGEHAYDTLSLESSDSMETSISTGG--NSACSPDNMSSASGLDMGKIEEME-KMLKE 1157
E E + + + + S+ G A N S + + E + K+ E
Sbjct: 1187 SQEGRE-----VQRQEAGELRRSLGEGAKEREALRRSNEELRSAVKKAESERISLKLANE 1241
Query: 1158 AHAEKNRLMESRE----REMELRRQALEEERRRREQVERRLQSESARRQQLVEKE 1208
+K L+E +E R L+E R R + R LQ E R+ ++++ E
Sbjct: 1242 DKEQKLALLEEARTAVGKEAGELRTGLQEVERSRLEARRELQ-ELRRQMKMLDSE 1295
Score = 65.5 bits (158), Expect = 3e-10
Identities = 156/695 (22%), Positives = 260/695 (37%), Gaps = 108/695 (15%)
Query: 287 ARSSSYHLALQPPQSRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRA 346
A ++ L L + R G +E R+ + GLR L L R
Sbjct: 1396 AEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALRRG-----LGLGRAP 1450
Query: 347 TESPRLGGQLPVVAISLSEYPASGA---LSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPP 403
+ +PR PV + PA G+ L+ P+++ SP QPP P P P
Sbjct: 1451 SPAPR-----PVPGSPARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPATS-------PA 1498
Query: 404 SPFREPPGSERVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELPPLSPS 463
SP +P L + D L T+T L R+ + E+ S
Sbjct: 1499 SPDLDPEAVRGALREFLQELRSAQRERDELRTQT------SALNRQ----LAEMEAERDS 1548
Query: 464 LSRRALSPLPTRTTPDPKLNREVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTL 523
+ RA +L + VAES RR S L L
Sbjct: 1549 ATSRA-----------RQLQKAVAESEEARRSVDGRLSGVQAELALQE------------ 1585
Query: 524 GESLAPHKGSFSGRLSPAYSLGSLTGASPCQSPCVQRKLS---SGDLRVPVTRERKNSIT 580
ES+ + L +L A+ + Q K+S + + ++ + R +
Sbjct: 1586 -ESVRRSERERRATLDQVATLERSLQATESELRASQEKISKMKANETKLEGDKRRLKEVL 1644
Query: 581 EISDNEDDLLEYHRRQRQERLREQEMERLERQ-RLETILNLCAEYSR--ADGGPEAGELP 637
+ S++ LE RR + L+ + +R+ + + + + R AD +AG L
Sbjct: 1645 DASESRTVKLELQRRSLEGELQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQ 1704
Query: 638 -SIGEATAALAL------AGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEE 690
++ ALA A R RGL A +SS S+ + ++NL +
Sbjct: 1705 LTVERLNGALAKVEESEGALRDKVRGLTEALAQSS-----------ASLNSTRDKNLHLQ 1753
Query: 691 -----CSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLG-HVEQLKVRVKELEQQLQES 744
C QE DA + L+ +++ LG V+ L+ V +LE Q E+
Sbjct: 1754 KALTACEHDRQVLQERLDAAR-----QALSEARKQSSSLGEQVQTLRGEVADLELQRVEA 1808
Query: 745 AREAEMERALLQGEREAERALLQKEQKAVDQ---LQEKLVALETGIQKERDKEAEALETE 801
+ + R +L+ +E E A L QK D+ LQE+L +L+ + + ++ E +
Sbjct: 1809 EGQLQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKREVERSA 1868
Query: 802 TKLFEDLEFQQLERESRVEEERELAGQGLLRSKAE---LLRSIAKRKERLAILDSQAGQI 858
+L +D +VE E+ + + +R AE L R++ + LA Q Q+
Sbjct: 1869 LRLEKD-RVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELELAEAQRQIQQL 1927
Query: 859 RAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLL 918
AQ V + ++ QL +++ L++ L + +T TL+ E+
Sbjct: 1928 EAQVV-----VLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQ--AQTERTLEARERAHR 1980
Query: 919 PAV-DLEQWYQ----ELMAGLGTGPAAASPHSSPP 948
V LE+ +L L A SP S PP
Sbjct: 1981 QRVRGLEEQVSTLKGQLQQELRRSSAPFSPPSGPP 2015
Score = 64.7 bits (156), Expect = 6e-10
Identities = 174/765 (22%), Positives = 306/765 (40%), Gaps = 142/765 (18%)
Query: 569 VPVTRERKNSITEISDNEDDLLEYHRRQRQERLREQEMER------LERQRLETILNLCA 622
V RE + S+ E ++ L+ +R+++ RE E ER L+R++ E + L A
Sbjct: 974 VQAEREAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLARLEA 1033
Query: 623 EYSRADGGPEA-------GELPSIGEATAALALAGRRPSRGLAGASGRSSEEPGVATQRL 675
E A G L + E AL+L + S A + +AT L
Sbjct: 1034 EKEELSEEIAALQQERDEGLLLAESEKQQALSL---KESEKTALSEKLMGTRHSLATISL 1090
Query: 676 WESMERSDEENLKEECSSTEST--------QQEHEDAPST------KLQGEVLALEEERA 721
++ D ++ +E+ ST + + + E+A + +LQ + L ++R
Sbjct: 1091 EMERQKRDAQSRQEQDRSTVNALTSELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRD 1150
Query: 722 QVLGHVEQLKVRVKELEQ----------QLQESAREA------------EMERALLQG-- 757
L E+L+ +++ LE + Q RE+ E+ R+L +G
Sbjct: 1151 SCLREAEELRTQLRLLEDARDGLRRELLEAQRKLRESQEGREVQRQEAGELRRSLGEGAK 1210
Query: 758 EREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLE-----FQQ 812
EREA R ++ + AV + + + ++L+ + + K A E T + ++ Q+
Sbjct: 1211 EREALRRSNEELRSAVKKAESERISLKLANEDKEQKLALLEEARTAVGKEAGELRTGLQE 1270
Query: 813 LERESRVEEERELAGQGLLRSKAELL--------RSIAKRKERLAILDSQAGQIRAQAVQ 864
+ER SR+E REL LR + ++L R +A+ + RLA+ + + R + +
Sbjct: 1271 VER-SRLEARRELQE---LRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRETLG 1326
Query: 865 ESERLARDKNASLQL-----------LQKEKEKLTVLERRY-HSLTGGRPFPKTTSTLKE 912
+RL + + ASL++ LQ+++ + ERR SL R K
Sbjct: 1327 LRQRLLKGE-ASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDHAR 1385
Query: 913 MEKLLLPAVDLE--QWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMD---- 966
+L L A E + L A G + + A QL RS +
Sbjct: 1386 GLELKLEAARAEAAELGLRLSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALRRGLG 1445
Query: 967 -GEATSPLPR------TRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSL- 1018
G A SP PR R P S +S S L + + PSP A T + L
Sbjct: 1446 LGRAPSPAPRPVPGSPARDAPAEGSGEGLNSPSTLECSPGSQPPSPGPA--TSPASPDLD 1503
Query: 1019 PRNLAATLQDIETKRQLALQQKGQQVIEEQ--RRRLAELK-------------QKAAAEA 1063
P + L++ + + A +++ + + R+LAE++ QKA AE+
Sbjct: 1504 PEAVRGALREFLQELRSAQRERDELRTQTSALNRQLAEMEAERDSATSRARQLQKAVAES 1563
Query: 1064 QCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETS 1123
+ ++ G +G L S+ R E A +L+ ++E S
Sbjct: 1564 EEARRSVDGRL---SGVQAELALQEESV--------RRSERERRA----TLDQVATLERS 1608
Query: 1124 ISTGGNSACSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEE 1183
+ + + S + K+E ++ LKE ESR ++EL+R++LE E
Sbjct: 1609 LQATESELRASQEKISKMKANETKLEGDKRRLKEVLDAS----ESRTVKLELQRRSLEGE 1664
Query: 1184 RRR-------REQVERRLQSE-SARRQQLVEKEVKMREKQFSQAR 1220
+R RE + LQ + ++Q+ + EVK Q + R
Sbjct: 1665 LQRSRLGLSDREAQAQALQDRVDSLQRQVADSEVKAGTLQLTVER 1709
Score = 58.9 bits (141), Expect = 3e-08
Identities = 147/738 (19%), Positives = 284/738 (38%), Gaps = 94/738 (12%)
Query: 543 SLGSLTGASPCQSPCVQRKLSSGDLRVPVTRERKNSITEISDNEDDLLEYHRRQRQERLR 602
S GSL G S ++P R+ S G R P R+ SD+ L H + +L+
Sbjct: 480 SNGSLRGLSGQRTPSPPRRSSPGRGRSP----RRGPSPACSDSST-LALIHSALHKRQLQ 534
Query: 603 EQEMERLERQRLETILNLCAEYSRADGGPEAGE--LPSIGEATAALALA---GRRPSRGL 657
Q+M + + L + S ++ A E L + + T A +R + L
Sbjct: 535 VQDMRGRYEASQDLLGTLRKQLSDSESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRL 594
Query: 658 AGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQE--------HEDAPSTKL 709
A+ S E L + ++++E L++E ++ Q+E E+
Sbjct: 595 RSANELLSREKSNLAHSLQVAQQQAEE--LRQEREKLQAAQEELRRQRDRLEEEQEDAVQ 652
Query: 710 QGEVLALEEERAQVLGHVEQLKVRVKELEQQL---QESAREAEMERALLQGER------- 759
G + E ER+ +EQL+ + L ++L +E+ A ++R +LQ E+
Sbjct: 653 DGARVRRELERSH--RQLEQLEGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVAEAL 710
Query: 760 ----------EAERALLQKEQKAVDQLQEKLVALETGIQKER----------DKEAEALE 799
E L+ E+ ++ KL AL + +++ ++E AL+
Sbjct: 711 TKAEAGRVELELSMTKLRAEEASLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQ 770
Query: 800 TETKLFEDLEFQQLERESRVEE---ERELAGQGLLRSKAELLRSIAKRKERLAILDSQAG 856
+ E E + R+EE E+E+A QGL S ++ +++L L +
Sbjct: 771 GRQRQAEQEATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERS 830
Query: 857 QIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKL 916
Q++ Q Q S +L+ + Q ++ + ++ LER + + KE L
Sbjct: 831 QLQEQLAQLSRQLSGREQELEQARREAQRQVEALERAAR---------EKEALAKEHAGL 881
Query: 917 LLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPL--P 974
+ V E+ + L + QL+ R +++ E + L
Sbjct: 882 AVQLVAAEREGRTLSEEATRLRLEKEALEGSLFEVQRQLAQLEARREQLEAEGQALLLAK 941
Query: 975 RTRSGPLP-------SSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTG------SLPRN 1021
T +G L ++ +S +L L ++ A L + L R
Sbjct: 942 ETLTGELAGLRQQIIATQEKASLDKELMAQKLVQAEREAQASLREQRAAHEEDLQRLQRE 1001
Query: 1022 LAATLQDIETKR---QLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPA 1078
A +++E +R Q LQ++ ++++ EL ++ AA Q + + L A
Sbjct: 1002 KEAAWRELEAERAQLQSQLQREQEELLARLEAEKEELSEEIAALQQERDEGLLLAESEKQ 1061
Query: 1079 GPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMS 1138
++ L R H+ T+SLE + S + + ++
Sbjct: 1062 QALSLKESEKTALSEKLMGTR-------HSLATISLEMERQKRDAQSRQEQDRSTVNALT 1114
Query: 1139 SASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQA-LEEERRRREQVERRLQSE 1197
S ++ + + AHA++ R ++ + R++ +R + L E R Q+ +
Sbjct: 1115 S----ELRDLRAQREEAAAAHAQEVRRLQEQARDLGKQRDSCLREAEELRTQLRLLEDAR 1170
Query: 1198 SARRQQLVEKEVKMREKQ 1215
R++L+E + K+RE Q
Sbjct: 1171 DGLRRELLEAQRKLRESQ 1188
Score = 58.9 bits (141), Expect = 3e-08
Identities = 130/559 (23%), Positives = 221/559 (39%), Gaps = 84/559 (15%)
Query: 677 ESMERSDEENLKEECSSTESTQQEHEDAPST--KLQGEVLALEEERAQVLGHVEQLKVRV 734
ES R+ EE L+ T+ Q HEDA +L+ L E++ + ++ + +
Sbjct: 560 ESERRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHSLQVAQQQA 619
Query: 735 KELEQQ---LQESAREAEMERALLQGERE---AERALLQKEQKAVDQLQEKLVALETGIQ 788
+EL Q+ LQ + E +R L+ E+E + A +++E + + E+L + +
Sbjct: 620 EELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQLEGKRSVLA 679
Query: 789 KERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKA---ELLRSIAKRK 845
KE + EAL T L+R+ E+ E+A + L +++A EL S+ K +
Sbjct: 680 KELVEVREALSRAT----------LQRDMLQAEKAEVA-EALTKAEAGRVELELSMTKLR 728
Query: 846 ERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPK 905
A L ++ A +E LA+DK +L+ + +E+ + L+ R +
Sbjct: 729 AEEASLQDSLSKLSAL----NESLAQDKLDLNRLVAQLEEEKSALQGRQRQAE-----QE 779
Query: 906 TTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKM 965
T +E E+L ++ E Q L L A P QLQ
Sbjct: 780 ATVAREEQERLEELRLEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQ------ 833
Query: 966 DGEATSPLPRTRSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAAT 1025
E + L R SG + +Q V L R+ K AL ++ LA
Sbjct: 834 --EQLAQLSRQLSGR-EQELEQARREAQRQVEALERAAREKEALAKEHA------GLAVQ 884
Query: 1026 LQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPP 1085
L +A +++G+ + EE A + + +AL G+
Sbjct: 885 L--------VAAEREGRTLSEE------------ATRLRLEKEALEGSL----------- 913
Query: 1086 LMHHSILHHLPAGRERGE-EGEH---AYDTLSLESSDSMETSISTGGNSACSPDNMSSAS 1141
L L A RE+ E EG+ A +TL+ E + + I+T S D A
Sbjct: 914 FEVQRQLAQLEARREQLEAEGQALLLAKETLTGELAGLRQQIIAT--QEKASLDKELMAQ 971
Query: 1142 GLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESARR 1201
L + E + L+E A ++ +RE E + LE ER + + +R Q E R
Sbjct: 972 KLVQAE-REAQASLREQRAAHEEDLQRLQREKEAAWRELEAERAQLQSQLQREQEELLAR 1030
Query: 1202 QQLVEKEVKMREKQFSQAR 1220
+ ++E+ Q R
Sbjct: 1031 LEAEKEELSEEIAALQQER 1049
Score = 44.7 bits (104), Expect = 6e-04
Identities = 139/625 (22%), Positives = 236/625 (37%), Gaps = 156/625 (24%)
Query: 679 MERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVL----GHVEQLKVRV 734
+E + L + QE + + KLQ ++ +AQ++ G + Q K R
Sbjct: 129 LETQEPRGLVRQSVELRRQLQEEQASYRRKLQAYQEG-QQRQAQLVQRLQGKILQYKKRC 187
Query: 735 KELEQQLQESAREAEMER------------ALLQGEREAERALLQKEQKA-----VDQLQ 777
ELEQQL E + E E +R AL++ E E +R+ + A +DQ
Sbjct: 188 SELEQQLLERSGELEQQRLRDTEHSQDLESALIRLEEEQQRSASLAQVNAMLREQLDQAG 247
Query: 778 EKLVALETGIQK-------------------ERDKEA----------------------E 796
AL I+K R++E+
Sbjct: 248 SANQALSEDIRKVTNDWTRCRKELEHREAAWRREEESFNAYFSNEHSRLLLLWRQVVGFR 307
Query: 797 ALETETKLFEDLEFQQLERE-SRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQA 855
L +E K+F + + QL E +R + AG GL LR R E A L+ QA
Sbjct: 308 RLVSEVKMFTERDLLQLGGELARTSRAVQEAGLGLSTG----LRLAESRAE--AALEKQA 361
Query: 856 GQIRAQAVQE-SERLARDKNASLQLLQKEKEK-----------LTVLERRYHSLTGGRPF 903
++AQ ++ +++ R+K+ + Q +Q + +K L V +L +
Sbjct: 362 -LLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVKRLEKQNLEKDQVN 420
Query: 904 PKTTSTLKEMEKLLL---PAVDLE--QWYQELMAGLGTGPAAASPHSSPPPLPAKASRQL 958
T L+ +E L L A++ E + Q+ + L A S S L + + R
Sbjct: 421 KDLTEKLEALESLRLQEQAALETEDGEGLQQTLRDL--AQAVLSDSESGVQL-SGSERTA 477
Query: 959 QVYRSKMDGEA--TSPLPRTRSGPLPSSS---GSSSSSSQLSVATLGRSPSPKSALLTQN 1013
+ G + +P P RS P S G S + S S L S K L Q+
Sbjct: 478 DASNGSLRGLSGQRTPSPPRRSSPGRGRSPRRGPSPACSDSSTLALIHSALHKRQLQVQD 537
Query: 1014 --GTGSLPRNLAATLQDIETKRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALH 1071
G ++L TL ++QL+ + ++ +EEQ +RL + K A +A
Sbjct: 538 MRGRYEASQDLLGTL-----RKQLSDSESERRALEEQLQRLRD-KTDGAMQA-------- 583
Query: 1072 GAAPFPAGPSGFPPLMHHSILHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSA 1131
H A RE + A + LS E S
Sbjct: 584 ----------------------HEDAQRE-VQRLRSANELLSREKS-------------- 606
Query: 1132 CSPDNMSSASGLDMGKIEEMEKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVE 1191
N++ + + + EE+ + ++ A + L R+R E + A+++ R R ++E
Sbjct: 607 ----NLAHSLQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELE 662
Query: 1192 ---RRLQSESARRQQLVEKEVKMRE 1213
R+L+ +R L ++ V++RE
Sbjct: 663 RSHRQLEQLEGKRSVLAKELVEVRE 687
Score = 43.1 bits (100), Expect = 0.002
Identities = 134/559 (23%), Positives = 215/559 (38%), Gaps = 113/559 (20%)
Query: 715 ALEEE---RAQVLGHVEQLKVRVKEL-EQQLQESAREAEMERALLQ---GEREAERALLQ 767
ALE++ +AQ+ + +R K+L +QQ+Q +A++ + + + E+ L+
Sbjct: 356 ALEKQALLQAQLEEQLRDKVLREKDLAQQQMQSDLDKADLSARVTELGLAVKRLEKQNLE 415
Query: 768 KEQKAVDQLQEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAG 827
K+Q D L EKL ALE+ R +E ALETE G
Sbjct: 416 KDQVNKD-LTEKLEALES----LRLQEQAALETED------------------------G 446
Query: 828 QGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEK--- 884
+GL ++ +L +++ + DS++G + SER A N SL+ L ++
Sbjct: 447 EGLQQTLRDLAQAV--------LSDSESG----VQLSGSERTADASNGSLRGLSGQRTPS 494
Query: 885 -EKLTVLERRYHSLTGGRPFPKTTSTL----KEMEKLLLPAVDLEQWYQELMAGLGTGPA 939
+ + R G P +STL + K L D+ Y+ LGT
Sbjct: 495 PPRRSSPGRGRSPRRGPSPACSDSSTLALIHSALHKRQLQVQDMRGRYEASQDLLGTLRK 554
Query: 940 AASPHSSPPPLPAKASRQLQVYRSKMDG------EATSPLPRTRSGPLPSSSGSSSSSSQ 993
S S QLQ R K DG +A + R RS S S+ +
Sbjct: 555 QLSDSESE---RRALEEQLQRLRDKTDGAMQAHEDAQREVQRLRSANELLSREKSNLAHS 611
Query: 994 LSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIE--------TKRQLALQQKGQQVI 1045
L VA + Q L R ++ E +R+L + + +
Sbjct: 612 LQVAQQQAEELRQEREKLQAAQEELRRQRDRLEEEQEDAVQDGARVRRELERSHRQLEQL 671
Query: 1046 EEQRRRLA-ELKQ--KAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHHLPAGRERG 1102
E +R LA EL + +A + A Q D L A L AGR
Sbjct: 672 EGKRSVLAKELVEVREALSRATLQRDMLQAEKAEVA-----------EALTKAEAGR--- 717
Query: 1103 EEGEHAYDTLSLESSDSMETSIS--TGGNSACSPD---------NMSSASGLDMGKIEEM 1151
E E + L E + S++ S+S + N + + D + G+ +
Sbjct: 718 VELELSMTKLRAEEA-SLQDSLSKLSALNESLAQDKLDLNRLVAQLEEEKSALQGRQRQA 776
Query: 1152 EKMLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSE--------SARRQQ 1203
E+ A E+ RL E R E E+ RQ LE R EQ + L+ + S ++Q
Sbjct: 777 EQEATVAREEQERLEELR-LEQEVARQGLEGSLRVAEQAQEALEQQLPTLRHERSQLQEQ 835
Query: 1204 LVE--KEVKMREKQFSQAR 1220
L + +++ RE++ QAR
Sbjct: 836 LAQLSRQLSGREQELEQAR 854
Score = 32.0 bits (71), Expect = 4.2
Identities = 35/148 (23%), Positives = 76/148 (51%), Gaps = 13/148 (8%)
Query: 751 ERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALETETK---LFED 807
E LLQ E LL + + D+L K A+ +++ E LET+ + +
Sbjct: 82 ENQLLQQELSRVEDLLAQSRAERDELAIKYNAVSERLEQALRLEPGELETQEPRGLVRQS 141
Query: 808 LEFQQLERESRVEEEREL-AGQGLLRSKAELLR----SIAKRKERLAILDSQ----AGQI 858
+E ++ +E + R+L A Q + +A+L++ I + K+R + L+ Q +G++
Sbjct: 142 VELRRQLQEEQASYRRKLQAYQEGQQRQAQLVQRLQGKILQYKKRCSELEQQLLERSGEL 201
Query: 859 RAQAVQESERLARDKNASLQLLQKEKEK 886
Q ++++E ++D ++L L++E+++
Sbjct: 202 EQQRLRDTEH-SQDLESALIRLEEEQQR 228
>gi|116284396 myosin, heavy chain 14 isoform 1 [Homo sapiens]
Length = 2003
Score = 69.3 bits (168), Expect = 2e-11
Identities = 98/409 (23%), Positives = 174/409 (42%), Gaps = 59/409 (14%)
Query: 587 DDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAAL 646
D+ E RRQ ++LR+ E+ER E ++ T+ + + ++ S G+
Sbjct: 1609 DEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEE- 1667
Query: 647 ALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLK-----------EECSSTE 695
A+ R + R EE + + ++ S R E+ LK E +S
Sbjct: 1668 AVKQLRKMQAQMKELWREVEETRTSREEIF-SQNRESEKRLKGLEAEVLRLQEELAASDR 1726
Query: 696 STQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEM----- 750
+ +Q +D ++ EV +A +L QL+ R+ +LE++L+E +E+
Sbjct: 1727 ARRQAQQD--RDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRY 1784
Query: 751 ERALLQ-----GEREAERALLQKEQKAVDQLQEKLVAL-------ETGIQKERDKEAEAL 798
+ LLQ E AER+ K + QL+ ++ L + G + AL
Sbjct: 1785 RKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAAL 1844
Query: 799 ETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDS----- 853
E++ E +QLE+E+R ER L+G+ + R++ L + + +E + D
Sbjct: 1845 ESKLAQAE----EQLEQETR---ERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQL 1897
Query: 854 QAGQIRA----QAVQESERLARDKNASLQLLQKEKEKLT-VLERRYHSLTGGR------P 902
+ G +R + ++E+E A A + LQ+E E +T E +T R P
Sbjct: 1898 EKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1957
Query: 903 FPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLP 951
TT T++++ + L V ++ +E G G P P SPP P
Sbjct: 1958 LTFTTRTVRQVFR-LEEGVASDEEAEEAQPGSGPSP---EPEGSPPAHP 2002
Score = 65.5 bits (158), Expect = 3e-10
Identities = 73/308 (23%), Positives = 130/308 (42%), Gaps = 41/308 (13%)
Query: 599 ERLREQEMERLERQRLET-------------ILNLCAEYSRADGGPEAGELPSIGEATAA 645
ER R + E+L+R + E + L E S + + E A
Sbjct: 1297 ERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAK 1356
Query: 646 LALAGR-RPSRGLAGASGRSSEEPGVATQRLWESMERSDEE------NLKEECSSTESTQ 698
LAL R R A EE A +R ++ + + +EE + E+ +
Sbjct: 1357 LALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGE 1416
Query: 699 QEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGE 758
+ A E AL + A+ V++L+ + L+Q+L ++ + E +R L+
Sbjct: 1417 EARRRAAR-----EAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLV--- 1468
Query: 759 REAERALLQKEQKAVDQL--QEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERE 816
+ L+K+Q+ DQL +EK L ++ER EAE E E + + E+E
Sbjct: 1469 -----STLEKKQRKFDQLLAEEKAAVLRAVEERER-AEAEGREREARALSLTRALEEEQE 1522
Query: 817 SRVEEERELAG-----QGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLAR 871
+R E ER+ + LL SK ++ +S+ + + + + A +RAQ + + L
Sbjct: 1523 AREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTA 1582
Query: 872 DKNASLQL 879
++A L+L
Sbjct: 1583 AEDAKLRL 1590
Score = 65.1 bits (157), Expect = 4e-10
Identities = 133/578 (23%), Positives = 230/578 (39%), Gaps = 89/578 (15%)
Query: 708 KLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQES-----AREAEMERALLQ-----G 757
+LQG V LEEERA++ EQL+ EL + +E+ AR+ E+E + + G
Sbjct: 902 ELQGRVAQLEEERARL---AEQLRAEA-ELCAEAEETRGRLAARKQELELVVSELEARVG 957
Query: 758 EREAERALLQKEQKAVDQLQEKLVA---LETGIQKERDKEAEALETETKLFEDLEFQQLE 814
E E +Q E+K + Q ++L A E G +++ E E + K FE+ +
Sbjct: 958 EEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLED 1017
Query: 815 RESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKN 874
+ S++ +ER+L L AE A+ +E++ L+ + A +RL ++
Sbjct: 1018 QNSKLSKERKLLEDRL----AEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE-- 1071
Query: 875 ASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGL 934
+K +++L L+RR E +L V+ +Q +EL A L
Sbjct: 1072 ------EKGRQELEKLKRRLDG---------------ESSELQEQMVEQQQRAEELRAQL 1110
Query: 935 G-------TGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSP-LPRTRS-------- 978
G A A K+ R+ Q ++ + S + RT++
Sbjct: 1111 GRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLG 1170
Query: 979 -------GPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIET 1031
G L + S+++ +L RS + + R A +Q++
Sbjct: 1171 EELEALRGELEDTLDSTNAQQEL------RSKREQEVTELKKTLEEETRIHEAAVQELRQ 1224
Query: 1032 KRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSI 1091
+ AL + +Q+ + +R + A K + A EA+ ++ A G +
Sbjct: 1225 RHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLEL 1284
Query: 1092 LHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPD-NMSSASGLDMGKIEE 1150
GR E A L+ + + ++S N A S +S ++ +
Sbjct: 1285 QLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHD 1344
Query: 1151 MEKMLKEAHAEKNRLMESREREMELR----RQALEEERRRREQVERRLQ------SESAR 1200
+++L+E K L SR R ME R+ LEEE RE+ R LQ SE R
Sbjct: 1345 AQELLQEETRAKLAL-GSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRR 1403
Query: 1201 RQQ----LVEKEVKMREKQFSQARPLTRYLPIRKEDFD 1234
RQ+ +E + R + +A LT+ L + E D
Sbjct: 1404 RQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD 1441
Score = 64.7 bits (156), Expect = 6e-10
Identities = 151/648 (23%), Positives = 250/648 (38%), Gaps = 134/648 (20%)
Query: 684 EENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQ- 742
E+ L++E E +QE E +L GE L+E+ + E+L+ ++ E++LQ
Sbjct: 1065 EDRLRKE----EKGRQELEKL-KRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQA 1119
Query: 743 ----------------ESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVAL--- 783
+S REA+ A Q + E+ER K +K L E+L AL
Sbjct: 1120 ALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGE 1179
Query: 784 ------ETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGL--LRSKA 835
T Q+E + E TE K + LE + E+ V+E R+ GQ L L +
Sbjct: 1180 LEDTLDSTNAQQELRSKREQEVTELK--KTLEEETRIHEAAVQELRQRHGQALGELAEQL 1237
Query: 836 ELLR--SIAKRKERLAILDSQAGQIRAQ------AVQESERLARDKNASLQLLQ------ 881
E R A K RLA L+++ ++RA+ A QE E+ R LQ +Q
Sbjct: 1238 EQARRGKGAWEKTRLA-LEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDG 1296
Query: 882 -----KEKEKLTVLERRYHSLTG--GRPFPKTTSTLKEMEKLLLPAVDLEQWYQ-ELMAG 933
+ EKL + +++G KT KE+ D ++ Q E A
Sbjct: 1297 ERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAK 1356
Query: 934 LGTGPAAASPHSSPPPL----------PAKASRQLQVYRSKMDGEATSPLPRTRSGPLPS 983
L G + + L +A R+LQ ++++ +G L +
Sbjct: 1357 LALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQL--SEWRRRQEEEAGALEA 1414
Query: 984 SSGSSSSSSQLSVATLGR-SPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLA-----L 1037
+ +++ + A R + ++ + G L + L D+E +RQL
Sbjct: 1415 GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKK 1474
Query: 1038 QQKGQQVIEEQRR---RLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHH 1094
Q+K Q++ E++ R E +++A AE
Sbjct: 1475 QRKFDQLLAEEKAAVLRAVEERERAEAE-------------------------------- 1502
Query: 1095 LPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGK-IEEMEK 1153
GRER E T +LE + + + +S D+GK + E+E+
Sbjct: 1503 ---GRER--EARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELER 1557
Query: 1154 MLKEAHAEKNRLMESREREMELRRQALEEERRRRE--------QVERRLQ-----SESAR 1200
+ A N L ++ E+E A E+ + R E Q ER LQ E R
Sbjct: 1558 ACRVAEQAANDL-RAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERR 1616
Query: 1201 RQ---QLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHG 1245
RQ QL + EV+ E++ + + + E +LK + S+G G
Sbjct: 1617 RQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQG 1664
Score = 62.0 bits (149), Expect = 4e-09
Identities = 114/509 (22%), Positives = 215/509 (42%), Gaps = 66/509 (12%)
Query: 588 DLLEYHRRQRQERLREQEME-RLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAAL 646
D LE RR+ Q+ L + M+ +RQ + T+ ++ + +A L ++ E A
Sbjct: 1441 DRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAE 1500
Query: 647 ALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQE-HE--- 702
A R +R L+ R+ EE A + L E R+ L+ SS + + HE
Sbjct: 1501 AEGREREARALSLT--RALEEEQEAREEL-ERQNRALRAELEALLSSKDDVGKSVHELER 1557
Query: 703 ------------DAPSTKLQGEVLALEEERAQVLGHVEQLKVRVK-----------ELEQ 739
A T+L+ E+ A E+ + ++ V+ LK + + E +
Sbjct: 1558 ACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRR 1617
Query: 740 QLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALE 799
QL + R+AE+ER + +R A +K + +++L+ ++ + G ++E K+ ++
Sbjct: 1618 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQG-KEEAVKQLRKMQ 1676
Query: 800 TETK-LFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQI 858
+ K L+ ++E + RE + RE + + L +AE+LR +E LA D Q
Sbjct: 1677 AQMKELWREVEETRTSREEIFSQNRE-SEKRLKGLEAEVLR----LQEELAASDRARRQA 1731
Query: 859 RAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTL--KEMEKL 916
+ + ++ +A + +L+++++ LE R L ++ S L KL
Sbjct: 1732 QQDRDEMADEVANGNLSKAAILEEKRQ----LEGRLGQLEEELEEEQSNSELLNDRYRKL 1787
Query: 917 LLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRT 976
LL +E EL A A S + RQ+Q R ++ E R
Sbjct: 1788 LL---QVESLTTELSAERSFSAKAESGRQ-------QLERQIQELRGRLGEEDAGARARH 1837
Query: 977 RSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLA 1036
+ S + + QL T R S K + + L + +E +R++A
Sbjct: 1838 KMTIAALESKLAQAEEQLEQETRERILSGKLVRRAE-------KRLKEVVLQVEEERRVA 1890
Query: 1037 LQ-----QKGQQVIEEQRRRLAELKQKAA 1060
Q +KG +++ +R+L E +++A+
Sbjct: 1891 DQLRDQLEKGNLRVKQLKRQLEEAEEEAS 1919
Score = 53.9 bits (128), Expect = 1e-06
Identities = 167/755 (22%), Positives = 284/755 (37%), Gaps = 115/755 (15%)
Query: 573 RERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPE 632
R+ + D E L+ ++Q+R E R + R E L + +GG
Sbjct: 1075 RQELEKLKRRLDGESSELQEQMVEQQQRAEEL---RAQLGRKEEELQAALARAEDEGGAR 1131
Query: 633 AGELPSIGEATAALA-----LAGRRPSRGLAGASGRS-SEEPGVATQRLWESMERSD--- 683
A L S+ EA AALA L R +R A R EE L ++++ ++
Sbjct: 1132 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1191
Query: 684 ------EENLKEECSSTESTQQEHEDAPSTKLQ------GEV------------------ 713
E+ + E + E + HE A Q GE+
Sbjct: 1192 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1251
Query: 714 LALEEERAQVLGHVEQLKV-------RVKELEQQLQE-SAREAEMERALLQGEREAERAL 765
LALE E +++ + L+ R + LE QLQE R + ERA + + +RA
Sbjct: 1252 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1311
Query: 766 --LQKEQKAVDQLQEKLVAL-----ETGIQKERDKEAEALETETKLFEDLEFQQLERES- 817
L+ A+++ + K + L T Q +E ET KL + +E E+
Sbjct: 1312 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1371
Query: 818 ----RVEEE---RELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLA 870
++EEE RE AG+ L ++A+L +++E L +AG+ + R A
Sbjct: 1372 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGAL--EAGE------EARRRAA 1423
Query: 871 RDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQEL 930
R+ A Q L ++ E + LER L + T L++ +L+ ++ + +L
Sbjct: 1424 REAEALTQRLAEKTETVDRLERGRRRLQ--QELDDATMDLEQQRQLVSTLEKKQRKFDQL 1481
Query: 931 MAGLGTGPAAASPHSSPPPLPA--KASRQLQVYRS-KMDGEATSPLPRTRSG------PL 981
+A A + +R L + R+ + + EA L R L
Sbjct: 1482 LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1541
Query: 982 PSSS---GSSSSSSQLSVATLGRSPSPKSALLTQ-----NGTGSLPRNLAATLQDIETKR 1033
SS G S + + ++ + A +T+ L T+Q ++T+
Sbjct: 1542 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1601
Query: 1034 QLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILH 1093
+ LQ + + EE+RR+LA KQ AE + + A L
Sbjct: 1602 ERDLQGR-DEAGEERRRQLA--KQLRDAEVERDEERKQRTLAVAARKK------LEGELE 1652
Query: 1094 HLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEK 1153
L A +G+ + M+ + S + + S + E EK
Sbjct: 1653 ELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN-------RESEK 1705
Query: 1154 MLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESA----RRQ---QLVE 1206
LK AE RL E RRQA ++ ++V S++A +RQ +L +
Sbjct: 1706 RLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQ 1765
Query: 1207 KEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIES 1241
E ++ E+Q + RY + + L T + +
Sbjct: 1766 LEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA 1800
Score = 41.2 bits (95), Expect = 0.007
Identities = 64/235 (27%), Positives = 105/235 (44%), Gaps = 20/235 (8%)
Query: 558 VQRKLSSGD-LRVPVTRERKNSITEISD---NEDDLLEYHRRQRQERLREQEMERLERQR 613
+Q +L++ D R ++R E+++ ++ +LE +RQ + RL + E E E Q
Sbjct: 1717 LQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILE-EKRQLEGRLGQLEEELEEEQS 1775
Query: 614 LETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRP-SRGLAGASGRSSEEPGVAT 672
+LN EL S + +A A +GR+ R + GR EE A
Sbjct: 1776 NSELLNDRYRKLLLQVESLTTEL-SAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1834
Query: 673 QR------LWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERA---QV 723
R ES EE L++E + + A +L+ VL +EEER Q+
Sbjct: 1835 ARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEK-RLKEVVLQVEEERRVADQL 1893
Query: 724 LGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQE 778
+E+ +RVK+L++QL+E+ EA +A G R +R L + A +E
Sbjct: 1894 RDQLEKGNLRVKQLKRQLEEAEEEASRAQA---GRRRLQRELEDVTESAESMNRE 1945
Score = 32.0 bits (71), Expect = 4.2
Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 6/84 (7%)
Query: 1158 AHAEKNR-LMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEK-----EVKM 1211
A AE+ R + +R++E+EL LE E+ R++Q+E R QQ +++ E +
Sbjct: 929 AEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEE 988
Query: 1212 REKQFSQARPLTRYLPIRKEDFDL 1235
+Q Q +T ++K + DL
Sbjct: 989 GARQKLQLEKVTTEAKMKKFEEDL 1012
Score = 32.0 bits (71), Expect = 4.2
Identities = 23/89 (25%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Query: 1147 KIEEMEKMLKEAHAEK---NRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQ 1203
K+ + E+ L++ E+ +L+ E+ ++ +EEERR +Q+ +L+ + R +Q
Sbjct: 1847 KLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQ 1906
Query: 1204 LVEKEVKMREKQFSQARPLTRYLPIRKED 1232
L +++++ E++ S+A+ R L ED
Sbjct: 1907 L-KRQLEEAEEEASRAQAGRRRLQRELED 1934
>gi|116284394 myosin, heavy chain 14 isoform 2 [Homo sapiens]
Length = 1995
Score = 69.3 bits (168), Expect = 2e-11
Identities = 98/409 (23%), Positives = 174/409 (42%), Gaps = 59/409 (14%)
Query: 587 DDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAAL 646
D+ E RRQ ++LR+ E+ER E ++ T+ + + ++ S G+
Sbjct: 1601 DEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEE- 1659
Query: 647 ALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLK-----------EECSSTE 695
A+ R + R EE + + ++ S R E+ LK E +S
Sbjct: 1660 AVKQLRKMQAQMKELWREVEETRTSREEIF-SQNRESEKRLKGLEAEVLRLQEELAASDR 1718
Query: 696 STQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEM----- 750
+ +Q +D ++ EV +A +L QL+ R+ +LE++L+E +E+
Sbjct: 1719 ARRQAQQD--RDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRY 1776
Query: 751 ERALLQ-----GEREAERALLQKEQKAVDQLQEKLVAL-------ETGIQKERDKEAEAL 798
+ LLQ E AER+ K + QL+ ++ L + G + AL
Sbjct: 1777 RKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAAL 1836
Query: 799 ETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDS----- 853
E++ E +QLE+E+R ER L+G+ + R++ L + + +E + D
Sbjct: 1837 ESKLAQAE----EQLEQETR---ERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQL 1889
Query: 854 QAGQIRA----QAVQESERLARDKNASLQLLQKEKEKLT-VLERRYHSLTGGR------P 902
+ G +R + ++E+E A A + LQ+E E +T E +T R P
Sbjct: 1890 EKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1949
Query: 903 FPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLP 951
TT T++++ + L V ++ +E G G P P SPP P
Sbjct: 1950 LTFTTRTVRQVFR-LEEGVASDEEAEEAQPGSGPSP---EPEGSPPAHP 1994
Score = 65.5 bits (158), Expect = 3e-10
Identities = 73/308 (23%), Positives = 130/308 (42%), Gaps = 41/308 (13%)
Query: 599 ERLREQEMERLERQRLET-------------ILNLCAEYSRADGGPEAGELPSIGEATAA 645
ER R + E+L+R + E + L E S + + E A
Sbjct: 1289 ERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAK 1348
Query: 646 LALAGR-RPSRGLAGASGRSSEEPGVATQRLWESMERSDEE------NLKEECSSTESTQ 698
LAL R R A EE A +R ++ + + +EE + E+ +
Sbjct: 1349 LALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGE 1408
Query: 699 QEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGE 758
+ A E AL + A+ V++L+ + L+Q+L ++ + E +R L+
Sbjct: 1409 EARRRAAR-----EAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLV--- 1460
Query: 759 REAERALLQKEQKAVDQL--QEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERE 816
+ L+K+Q+ DQL +EK L ++ER EAE E E + + E+E
Sbjct: 1461 -----STLEKKQRKFDQLLAEEKAAVLRAVEERER-AEAEGREREARALSLTRALEEEQE 1514
Query: 817 SRVEEERELAG-----QGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLAR 871
+R E ER+ + LL SK ++ +S+ + + + + A +RAQ + + L
Sbjct: 1515 AREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTA 1574
Query: 872 DKNASLQL 879
++A L+L
Sbjct: 1575 AEDAKLRL 1582
Score = 65.1 bits (157), Expect = 4e-10
Identities = 133/578 (23%), Positives = 230/578 (39%), Gaps = 89/578 (15%)
Query: 708 KLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQES-----AREAEMERALLQ-----G 757
+LQG V LEEERA++ EQL+ EL + +E+ AR+ E+E + + G
Sbjct: 894 ELQGRVAQLEEERARL---AEQLRAEA-ELCAEAEETRGRLAARKQELELVVSELEARVG 949
Query: 758 EREAERALLQKEQKAVDQLQEKLVA---LETGIQKERDKEAEALETETKLFEDLEFQQLE 814
E E +Q E+K + Q ++L A E G +++ E E + K FE+ +
Sbjct: 950 EEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLED 1009
Query: 815 RESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKN 874
+ S++ +ER+L L AE A+ +E++ L+ + A +RL ++
Sbjct: 1010 QNSKLSKERKLLEDRL----AEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE-- 1063
Query: 875 ASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGL 934
+K +++L L+RR E +L V+ +Q +EL A L
Sbjct: 1064 ------EKGRQELEKLKRRLDG---------------ESSELQEQMVEQQQRAEELRAQL 1102
Query: 935 G-------TGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSP-LPRTRS-------- 978
G A A K+ R+ Q ++ + S + RT++
Sbjct: 1103 GRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLG 1162
Query: 979 -------GPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIET 1031
G L + S+++ +L RS + + R A +Q++
Sbjct: 1163 EELEALRGELEDTLDSTNAQQEL------RSKREQEVTELKKTLEEETRIHEAAVQELRQ 1216
Query: 1032 KRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSI 1091
+ AL + +Q+ + +R + A K + A EA+ ++ A G +
Sbjct: 1217 RHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLEL 1276
Query: 1092 LHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPD-NMSSASGLDMGKIEE 1150
GR E A L+ + + ++S N A S +S ++ +
Sbjct: 1277 QLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHD 1336
Query: 1151 MEKMLKEAHAEKNRLMESREREMELR----RQALEEERRRREQVERRLQ------SESAR 1200
+++L+E K L SR R ME R+ LEEE RE+ R LQ SE R
Sbjct: 1337 AQELLQEETRAKLAL-GSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRR 1395
Query: 1201 RQQ----LVEKEVKMREKQFSQARPLTRYLPIRKEDFD 1234
RQ+ +E + R + +A LT+ L + E D
Sbjct: 1396 RQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD 1433
Score = 64.7 bits (156), Expect = 6e-10
Identities = 151/648 (23%), Positives = 250/648 (38%), Gaps = 134/648 (20%)
Query: 684 EENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQ- 742
E+ L++E E +QE E +L GE L+E+ + E+L+ ++ E++LQ
Sbjct: 1057 EDRLRKE----EKGRQELEKL-KRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQA 1111
Query: 743 ----------------ESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVAL--- 783
+S REA+ A Q + E+ER K +K L E+L AL
Sbjct: 1112 ALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGE 1171
Query: 784 ------ETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGL--LRSKA 835
T Q+E + E TE K + LE + E+ V+E R+ GQ L L +
Sbjct: 1172 LEDTLDSTNAQQELRSKREQEVTELK--KTLEEETRIHEAAVQELRQRHGQALGELAEQL 1229
Query: 836 ELLR--SIAKRKERLAILDSQAGQIRAQ------AVQESERLARDKNASLQLLQ------ 881
E R A K RLA L+++ ++RA+ A QE E+ R LQ +Q
Sbjct: 1230 EQARRGKGAWEKTRLA-LEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDG 1288
Query: 882 -----KEKEKLTVLERRYHSLTG--GRPFPKTTSTLKEMEKLLLPAVDLEQWYQ-ELMAG 933
+ EKL + +++G KT KE+ D ++ Q E A
Sbjct: 1289 ERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAK 1348
Query: 934 LGTGPAAASPHSSPPPL----------PAKASRQLQVYRSKMDGEATSPLPRTRSGPLPS 983
L G + + L +A R+LQ ++++ +G L +
Sbjct: 1349 LALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQL--SEWRRRQEEEAGALEA 1406
Query: 984 SSGSSSSSSQLSVATLGR-SPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLA-----L 1037
+ +++ + A R + ++ + G L + L D+E +RQL
Sbjct: 1407 GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKK 1466
Query: 1038 QQKGQQVIEEQRR---RLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHH 1094
Q+K Q++ E++ R E +++A AE
Sbjct: 1467 QRKFDQLLAEEKAAVLRAVEERERAEAE-------------------------------- 1494
Query: 1095 LPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGK-IEEMEK 1153
GRER E T +LE + + + +S D+GK + E+E+
Sbjct: 1495 ---GRER--EARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELER 1549
Query: 1154 MLKEAHAEKNRLMESREREMELRRQALEEERRRRE--------QVERRLQ-----SESAR 1200
+ A N L ++ E+E A E+ + R E Q ER LQ E R
Sbjct: 1550 ACRVAEQAANDL-RAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERR 1608
Query: 1201 RQ---QLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHG 1245
RQ QL + EV+ E++ + + + E +LK + S+G G
Sbjct: 1609 RQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQG 1656
Score = 62.0 bits (149), Expect = 4e-09
Identities = 114/509 (22%), Positives = 215/509 (42%), Gaps = 66/509 (12%)
Query: 588 DLLEYHRRQRQERLREQEME-RLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAAL 646
D LE RR+ Q+ L + M+ +RQ + T+ ++ + +A L ++ E A
Sbjct: 1433 DRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAE 1492
Query: 647 ALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQE-HE--- 702
A R +R L+ R+ EE A + L E R+ L+ SS + + HE
Sbjct: 1493 AEGREREARALSLT--RALEEEQEAREEL-ERQNRALRAELEALLSSKDDVGKSVHELER 1549
Query: 703 ------------DAPSTKLQGEVLALEEERAQVLGHVEQLKVRVK-----------ELEQ 739
A T+L+ E+ A E+ + ++ V+ LK + + E +
Sbjct: 1550 ACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRR 1609
Query: 740 QLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALE 799
QL + R+AE+ER + +R A +K + +++L+ ++ + G ++E K+ ++
Sbjct: 1610 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQG-KEEAVKQLRKMQ 1668
Query: 800 TETK-LFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQI 858
+ K L+ ++E + RE + RE + + L +AE+LR +E LA D Q
Sbjct: 1669 AQMKELWREVEETRTSREEIFSQNRE-SEKRLKGLEAEVLR----LQEELAASDRARRQA 1723
Query: 859 RAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTL--KEMEKL 916
+ + ++ +A + +L+++++ LE R L ++ S L KL
Sbjct: 1724 QQDRDEMADEVANGNLSKAAILEEKRQ----LEGRLGQLEEELEEEQSNSELLNDRYRKL 1779
Query: 917 LLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRT 976
LL +E EL A A S + RQ+Q R ++ E R
Sbjct: 1780 LL---QVESLTTELSAERSFSAKAESGRQ-------QLERQIQELRGRLGEEDAGARARH 1829
Query: 977 RSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLA 1036
+ S + + QL T R S K + + L + +E +R++A
Sbjct: 1830 KMTIAALESKLAQAEEQLEQETRERILSGKLVRRAE-------KRLKEVVLQVEEERRVA 1882
Query: 1037 LQ-----QKGQQVIEEQRRRLAELKQKAA 1060
Q +KG +++ +R+L E +++A+
Sbjct: 1883 DQLRDQLEKGNLRVKQLKRQLEEAEEEAS 1911
Score = 53.9 bits (128), Expect = 1e-06
Identities = 167/755 (22%), Positives = 284/755 (37%), Gaps = 115/755 (15%)
Query: 573 RERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPE 632
R+ + D E L+ ++Q+R E R + R E L + +GG
Sbjct: 1067 RQELEKLKRRLDGESSELQEQMVEQQQRAEEL---RAQLGRKEEELQAALARAEDEGGAR 1123
Query: 633 AGELPSIGEATAALA-----LAGRRPSRGLAGASGRS-SEEPGVATQRLWESMERSD--- 683
A L S+ EA AALA L R +R A R EE L ++++ ++
Sbjct: 1124 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1183
Query: 684 ------EENLKEECSSTESTQQEHEDAPSTKLQ------GEV------------------ 713
E+ + E + E + HE A Q GE+
Sbjct: 1184 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1243
Query: 714 LALEEERAQVLGHVEQLKV-------RVKELEQQLQE-SAREAEMERALLQGEREAERAL 765
LALE E +++ + L+ R + LE QLQE R + ERA + + +RA
Sbjct: 1244 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1303
Query: 766 --LQKEQKAVDQLQEKLVAL-----ETGIQKERDKEAEALETETKLFEDLEFQQLERES- 817
L+ A+++ + K + L T Q +E ET KL + +E E+
Sbjct: 1304 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1363
Query: 818 ----RVEEE---RELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLA 870
++EEE RE AG+ L ++A+L +++E L +AG+ + R A
Sbjct: 1364 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGAL--EAGE------EARRRAA 1415
Query: 871 RDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQEL 930
R+ A Q L ++ E + LER L + T L++ +L+ ++ + +L
Sbjct: 1416 REAEALTQRLAEKTETVDRLERGRRRLQ--QELDDATMDLEQQRQLVSTLEKKQRKFDQL 1473
Query: 931 MAGLGTGPAAASPHSSPPPLPA--KASRQLQVYRS-KMDGEATSPLPRTRSG------PL 981
+A A + +R L + R+ + + EA L R L
Sbjct: 1474 LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1533
Query: 982 PSSS---GSSSSSSQLSVATLGRSPSPKSALLTQ-----NGTGSLPRNLAATLQDIETKR 1033
SS G S + + ++ + A +T+ L T+Q ++T+
Sbjct: 1534 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1593
Query: 1034 QLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILH 1093
+ LQ + + EE+RR+LA KQ AE + + A L
Sbjct: 1594 ERDLQGR-DEAGEERRRQLA--KQLRDAEVERDEERKQRTLAVAARKK------LEGELE 1644
Query: 1094 HLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEK 1153
L A +G+ + M+ + S + + S + E EK
Sbjct: 1645 ELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN-------RESEK 1697
Query: 1154 MLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESA----RRQ---QLVE 1206
LK AE RL E RRQA ++ ++V S++A +RQ +L +
Sbjct: 1698 RLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQ 1757
Query: 1207 KEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIES 1241
E ++ E+Q + RY + + L T + +
Sbjct: 1758 LEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA 1792
Score = 41.2 bits (95), Expect = 0.007
Identities = 64/235 (27%), Positives = 105/235 (44%), Gaps = 20/235 (8%)
Query: 558 VQRKLSSGD-LRVPVTRERKNSITEISD---NEDDLLEYHRRQRQERLREQEMERLERQR 613
+Q +L++ D R ++R E+++ ++ +LE +RQ + RL + E E E Q
Sbjct: 1709 LQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILE-EKRQLEGRLGQLEEELEEEQS 1767
Query: 614 LETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRP-SRGLAGASGRSSEEPGVAT 672
+LN EL S + +A A +GR+ R + GR EE A
Sbjct: 1768 NSELLNDRYRKLLLQVESLTTEL-SAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1826
Query: 673 QR------LWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERA---QV 723
R ES EE L++E + + A +L+ VL +EEER Q+
Sbjct: 1827 ARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEK-RLKEVVLQVEEERRVADQL 1885
Query: 724 LGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQE 778
+E+ +RVK+L++QL+E+ EA +A G R +R L + A +E
Sbjct: 1886 RDQLEKGNLRVKQLKRQLEEAEEEASRAQA---GRRRLQRELEDVTESAESMNRE 1937
Score = 32.0 bits (71), Expect = 4.2
Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 6/84 (7%)
Query: 1158 AHAEKNR-LMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEK-----EVKM 1211
A AE+ R + +R++E+EL LE E+ R++Q+E R QQ +++ E +
Sbjct: 921 AEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEE 980
Query: 1212 REKQFSQARPLTRYLPIRKEDFDL 1235
+Q Q +T ++K + DL
Sbjct: 981 GARQKLQLEKVTTEAKMKKFEEDL 1004
Score = 32.0 bits (71), Expect = 4.2
Identities = 23/89 (25%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Query: 1147 KIEEMEKMLKEAHAEK---NRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQ 1203
K+ + E+ L++ E+ +L+ E+ ++ +EEERR +Q+ +L+ + R +Q
Sbjct: 1839 KLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQ 1898
Query: 1204 LVEKEVKMREKQFSQARPLTRYLPIRKED 1232
L +++++ E++ S+A+ R L ED
Sbjct: 1899 L-KRQLEEAEEEASRAQAGRRRLQRELED 1926
>gi|224831241 myosin, heavy chain 14 isoform 3 [Homo sapiens]
Length = 2036
Score = 69.3 bits (168), Expect = 2e-11
Identities = 98/409 (23%), Positives = 174/409 (42%), Gaps = 59/409 (14%)
Query: 587 DDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAAL 646
D+ E RRQ ++LR+ E+ER E ++ T+ + + ++ S G+
Sbjct: 1642 DEAGEERRRQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQGKEE- 1700
Query: 647 ALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLK-----------EECSSTE 695
A+ R + R EE + + ++ S R E+ LK E +S
Sbjct: 1701 AVKQLRKMQAQMKELWREVEETRTSREEIF-SQNRESEKRLKGLEAEVLRLQEELAASDR 1759
Query: 696 STQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEM----- 750
+ +Q +D ++ EV +A +L QL+ R+ +LE++L+E +E+
Sbjct: 1760 ARRQAQQD--RDEMADEVANGNLSKAAILEEKRQLEGRLGQLEEELEEEQSNSELLNDRY 1817
Query: 751 ERALLQ-----GEREAERALLQKEQKAVDQLQEKLVAL-------ETGIQKERDKEAEAL 798
+ LLQ E AER+ K + QL+ ++ L + G + AL
Sbjct: 1818 RKLLLQVESLTTELSAERSFSAKAESGRQQLERQIQELRGRLGEEDAGARARHKMTIAAL 1877
Query: 799 ETETKLFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDS----- 853
E++ E +QLE+E+R ER L+G+ + R++ L + + +E + D
Sbjct: 1878 ESKLAQAE----EQLEQETR---ERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQL 1930
Query: 854 QAGQIRA----QAVQESERLARDKNASLQLLQKEKEKLT-VLERRYHSLTGGR------P 902
+ G +R + ++E+E A A + LQ+E E +T E +T R P
Sbjct: 1931 EKGNLRVKQLKRQLEEAEEEASRAQAGRRRLQRELEDVTESAESMNREVTTLRNRLRRGP 1990
Query: 903 FPKTTSTLKEMEKLLLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLP 951
TT T++++ + L V ++ +E G G P P SPP P
Sbjct: 1991 LTFTTRTVRQVFR-LEEGVASDEEAEEAQPGSGPSP---EPEGSPPAHP 2035
Score = 65.5 bits (158), Expect = 3e-10
Identities = 73/308 (23%), Positives = 130/308 (42%), Gaps = 41/308 (13%)
Query: 599 ERLREQEMERLERQRLET-------------ILNLCAEYSRADGGPEAGELPSIGEATAA 645
ER R + E+L+R + E + L E S + + E A
Sbjct: 1330 ERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAK 1389
Query: 646 LALAGR-RPSRGLAGASGRSSEEPGVATQRLWESMERSDEE------NLKEECSSTESTQ 698
LAL R R A EE A +R ++ + + +EE + E+ +
Sbjct: 1390 LALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGALEAGE 1449
Query: 699 QEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGE 758
+ A E AL + A+ V++L+ + L+Q+L ++ + E +R L+
Sbjct: 1450 EARRRAAR-----EAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLV--- 1501
Query: 759 REAERALLQKEQKAVDQL--QEKLVALETGIQKERDKEAEALETETKLFEDLEFQQLERE 816
+ L+K+Q+ DQL +EK L ++ER EAE E E + + E+E
Sbjct: 1502 -----STLEKKQRKFDQLLAEEKAAVLRAVEERER-AEAEGREREARALSLTRALEEEQE 1555
Query: 817 SRVEEERELAG-----QGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLAR 871
+R E ER+ + LL SK ++ +S+ + + + + A +RAQ + + L
Sbjct: 1556 AREELERQNRALRAELEALLSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTA 1615
Query: 872 DKNASLQL 879
++A L+L
Sbjct: 1616 AEDAKLRL 1623
Score = 65.1 bits (157), Expect = 4e-10
Identities = 133/578 (23%), Positives = 230/578 (39%), Gaps = 89/578 (15%)
Query: 708 KLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQES-----AREAEMERALLQ-----G 757
+LQG V LEEERA++ EQL+ EL + +E+ AR+ E+E + + G
Sbjct: 935 ELQGRVAQLEEERARL---AEQLRAEA-ELCAEAEETRGRLAARKQELELVVSELEARVG 990
Query: 758 EREAERALLQKEQKAVDQLQEKLVA---LETGIQKERDKEAEALETETKLFEDLEFQQLE 814
E E +Q E+K + Q ++L A E G +++ E E + K FE+ +
Sbjct: 991 EEEECSRQMQTEKKRLQQHIQELEAHLEAEEGARQKLQLEKVTTEAKMKKFEEDLLLLED 1050
Query: 815 RESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLARDKN 874
+ S++ +ER+L L AE A+ +E++ L+ + A +RL ++
Sbjct: 1051 QNSKLSKERKLLEDRL----AEFSSQAAEEEEKVKSLNKLRLKYEATIADMEDRLRKE-- 1104
Query: 875 ASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQELMAGL 934
+K +++L L+RR E +L V+ +Q +EL A L
Sbjct: 1105 ------EKGRQELEKLKRRLDG---------------ESSELQEQMVEQQQRAEELRAQL 1143
Query: 935 G-------TGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSP-LPRTRS-------- 978
G A A K+ R+ Q ++ + S + RT++
Sbjct: 1144 GRKEEELQAALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLG 1203
Query: 979 -------GPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIET 1031
G L + S+++ +L RS + + R A +Q++
Sbjct: 1204 EELEALRGELEDTLDSTNAQQEL------RSKREQEVTELKKTLEEETRIHEAAVQELRQ 1257
Query: 1032 KRQLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSI 1091
+ AL + +Q+ + +R + A K + A EA+ ++ A G +
Sbjct: 1258 RHGQALGELAEQLEQARRGKGAWEKTRLALEAEVSELRAELSSLQTARQEGEQRRRRLEL 1317
Query: 1092 LHHLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPD-NMSSASGLDMGKIEE 1150
GR E A L+ + + ++S N A S +S ++ +
Sbjct: 1318 QLQEVQGRAGDGERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHD 1377
Query: 1151 MEKMLKEAHAEKNRLMESREREMELR----RQALEEERRRREQVERRLQ------SESAR 1200
+++L+E K L SR R ME R+ LEEE RE+ R LQ SE R
Sbjct: 1378 AQELLQEETRAKLAL-GSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQLSEWRR 1436
Query: 1201 RQQ----LVEKEVKMREKQFSQARPLTRYLPIRKEDFD 1234
RQ+ +E + R + +A LT+ L + E D
Sbjct: 1437 RQEEEAGALEAGEEARRRAAREAEALTQRLAEKTETVD 1474
Score = 64.7 bits (156), Expect = 6e-10
Identities = 151/648 (23%), Positives = 250/648 (38%), Gaps = 134/648 (20%)
Query: 684 EENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQ- 742
E+ L++E E +QE E +L GE L+E+ + E+L+ ++ E++LQ
Sbjct: 1098 EDRLRKE----EKGRQELEKL-KRRLDGESSELQEQMVEQQQRAEELRAQLGRKEEELQA 1152
Query: 743 ----------------ESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVAL--- 783
+S REA+ A Q + E+ER K +K L E+L AL
Sbjct: 1153 ALARAEDEGGARAQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGE 1212
Query: 784 ------ETGIQKERDKEAEALETETKLFEDLEFQQLERESRVEEERELAGQGL--LRSKA 835
T Q+E + E TE K + LE + E+ V+E R+ GQ L L +
Sbjct: 1213 LEDTLDSTNAQQELRSKREQEVTELK--KTLEEETRIHEAAVQELRQRHGQALGELAEQL 1270
Query: 836 ELLR--SIAKRKERLAILDSQAGQIRAQ------AVQESERLARDKNASLQLLQ------ 881
E R A K RLA L+++ ++RA+ A QE E+ R LQ +Q
Sbjct: 1271 EQARRGKGAWEKTRLA-LEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDG 1329
Query: 882 -----KEKEKLTVLERRYHSLTG--GRPFPKTTSTLKEMEKLLLPAVDLEQWYQ-ELMAG 933
+ EKL + +++G KT KE+ D ++ Q E A
Sbjct: 1330 ERARAEAAEKLQRAQAELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAK 1389
Query: 934 LGTGPAAASPHSSPPPL----------PAKASRQLQVYRSKMDGEATSPLPRTRSGPLPS 983
L G + + L +A R+LQ ++++ +G L +
Sbjct: 1390 LALGSRVRAMEAEAAGLREQLEEEAAARERAGRELQTAQAQL--SEWRRRQEEEAGALEA 1447
Query: 984 SSGSSSSSSQLSVATLGR-SPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLA-----L 1037
+ +++ + A R + ++ + G L + L D+E +RQL
Sbjct: 1448 GEEARRRAAREAEALTQRLAEKTETVDRLERGRRRLQQELDDATMDLEQQRQLVSTLEKK 1507
Query: 1038 QQKGQQVIEEQRR---RLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILHH 1094
Q+K Q++ E++ R E +++A AE
Sbjct: 1508 QRKFDQLLAEEKAAVLRAVEERERAEAE-------------------------------- 1535
Query: 1095 LPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGK-IEEMEK 1153
GRER E T +LE + + + +S D+GK + E+E+
Sbjct: 1536 ---GRER--EARALSLTRALEEEQEAREELERQNRALRAELEALLSSKDDVGKSVHELER 1590
Query: 1154 MLKEAHAEKNRLMESREREMELRRQALEEERRRRE--------QVERRLQ-----SESAR 1200
+ A N L ++ E+E A E+ + R E Q ER LQ E R
Sbjct: 1591 ACRVAEQAANDL-RAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERR 1649
Query: 1201 RQ---QLVEKEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIESSGHG 1245
RQ QL + EV+ E++ + + + E +LK + S+G G
Sbjct: 1650 RQLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQG 1697
Score = 62.0 bits (149), Expect = 4e-09
Identities = 114/509 (22%), Positives = 215/509 (42%), Gaps = 66/509 (12%)
Query: 588 DLLEYHRRQRQERLREQEME-RLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAAL 646
D LE RR+ Q+ L + M+ +RQ + T+ ++ + +A L ++ E A
Sbjct: 1474 DRLERGRRRLQQELDDATMDLEQQRQLVSTLEKKQRKFDQLLAEEKAAVLRAVEERERAE 1533
Query: 647 ALAGRRPSRGLAGASGRSSEEPGVATQRLWESMERSDEENLKEECSSTESTQQE-HE--- 702
A R +R L+ R+ EE A + L E R+ L+ SS + + HE
Sbjct: 1534 AEGREREARALSLT--RALEEEQEAREEL-ERQNRALRAELEALLSSKDDVGKSVHELER 1590
Query: 703 ------------DAPSTKLQGEVLALEEERAQVLGHVEQLKVRVK-----------ELEQ 739
A T+L+ E+ A E+ + ++ V+ LK + + E +
Sbjct: 1591 ACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQHERDLQGRDEAGEERRR 1650
Query: 740 QLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQEKLVALETGIQKERDKEAEALE 799
QL + R+AE+ER + +R A +K + +++L+ ++ + G ++E K+ ++
Sbjct: 1651 QLAKQLRDAEVERDEERKQRTLAVAARKKLEGELEELKAQMASAGQG-KEEAVKQLRKMQ 1709
Query: 800 TETK-LFEDLEFQQLERESRVEEERELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQI 858
+ K L+ ++E + RE + RE + + L +AE+LR +E LA D Q
Sbjct: 1710 AQMKELWREVEETRTSREEIFSQNRE-SEKRLKGLEAEVLR----LQEELAASDRARRQA 1764
Query: 859 RAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTL--KEMEKL 916
+ + ++ +A + +L+++++ LE R L ++ S L KL
Sbjct: 1765 QQDRDEMADEVANGNLSKAAILEEKRQ----LEGRLGQLEEELEEEQSNSELLNDRYRKL 1820
Query: 917 LLPAVDLEQWYQELMAGLGTGPAAASPHSSPPPLPAKASRQLQVYRSKMDGEATSPLPRT 976
LL +E EL A A S + RQ+Q R ++ E R
Sbjct: 1821 LL---QVESLTTELSAERSFSAKAESGRQ-------QLERQIQELRGRLGEEDAGARARH 1870
Query: 977 RSGPLPSSSGSSSSSSQLSVATLGRSPSPKSALLTQNGTGSLPRNLAATLQDIETKRQLA 1036
+ S + + QL T R S K + + L + +E +R++A
Sbjct: 1871 KMTIAALESKLAQAEEQLEQETRERILSGKLVRRAE-------KRLKEVVLQVEEERRVA 1923
Query: 1037 LQ-----QKGQQVIEEQRRRLAELKQKAA 1060
Q +KG +++ +R+L E +++A+
Sbjct: 1924 DQLRDQLEKGNLRVKQLKRQLEEAEEEAS 1952
Score = 53.9 bits (128), Expect = 1e-06
Identities = 167/755 (22%), Positives = 284/755 (37%), Gaps = 115/755 (15%)
Query: 573 RERKNSITEISDNEDDLLEYHRRQRQERLREQEMERLERQRLETILNLCAEYSRADGGPE 632
R+ + D E L+ ++Q+R E R + R E L + +GG
Sbjct: 1108 RQELEKLKRRLDGESSELQEQMVEQQQRAEEL---RAQLGRKEEELQAALARAEDEGGAR 1164
Query: 633 AGELPSIGEATAALA-----LAGRRPSRGLAGASGRS-SEEPGVATQRLWESMERSD--- 683
A L S+ EA AALA L R +R A R EE L ++++ ++
Sbjct: 1165 AQLLKSLREAQAALAEAQEDLESERVARTKAEKQRRDLGEELEALRGELEDTLDSTNAQQ 1224
Query: 684 ------EENLKEECSSTESTQQEHEDAPSTKLQ------GEV------------------ 713
E+ + E + E + HE A Q GE+
Sbjct: 1225 ELRSKREQEVTELKKTLEEETRIHEAAVQELRQRHGQALGELAEQLEQARRGKGAWEKTR 1284
Query: 714 LALEEERAQVLGHVEQLKV-------RVKELEQQLQE-SAREAEMERALLQGEREAERAL 765
LALE E +++ + L+ R + LE QLQE R + ERA + + +RA
Sbjct: 1285 LALEAEVSELRAELSSLQTARQEGEQRRRRLELQLQEVQGRAGDGERARAEAAEKLQRAQ 1344
Query: 766 --LQKEQKAVDQLQEKLVAL-----ETGIQKERDKEAEALETETKLFEDLEFQQLERES- 817
L+ A+++ + K + L T Q +E ET KL + +E E+
Sbjct: 1345 AELENVSGALNEAESKTIRLSKELSSTEAQLHDAQELLQEETRAKLALGSRVRAMEAEAA 1404
Query: 818 ----RVEEE---RELAGQGLLRSKAELLRSIAKRKERLAILDSQAGQIRAQAVQESERLA 870
++EEE RE AG+ L ++A+L +++E L +AG+ + R A
Sbjct: 1405 GLREQLEEEAAARERAGRELQTAQAQLSEWRRRQEEEAGAL--EAGE------EARRRAA 1456
Query: 871 RDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTTSTLKEMEKLLLPAVDLEQWYQEL 930
R+ A Q L ++ E + LER L + T L++ +L+ ++ + +L
Sbjct: 1457 REAEALTQRLAEKTETVDRLERGRRRLQ--QELDDATMDLEQQRQLVSTLEKKQRKFDQL 1514
Query: 931 MAGLGTGPAAASPHSSPPPLPA--KASRQLQVYRS-KMDGEATSPLPRTRSG------PL 981
+A A + +R L + R+ + + EA L R L
Sbjct: 1515 LAEEKAAVLRAVEERERAEAEGREREARALSLTRALEEEQEAREELERQNRALRAELEAL 1574
Query: 982 PSSS---GSSSSSSQLSVATLGRSPSPKSALLTQ-----NGTGSLPRNLAATLQDIETKR 1033
SS G S + + ++ + A +T+ L T+Q ++T+
Sbjct: 1575 LSSKDDVGKSVHELERACRVAEQAANDLRAQVTELEDELTAAEDAKLRLEVTVQALKTQH 1634
Query: 1034 QLALQQKGQQVIEEQRRRLAELKQKAAAEAQCQWDALHGAAPFPAGPSGFPPLMHHSILH 1093
+ LQ + + EE+RR+LA KQ AE + + A L
Sbjct: 1635 ERDLQGR-DEAGEERRRQLA--KQLRDAEVERDEERKQRTLAVAARKK------LEGELE 1685
Query: 1094 HLPAGRERGEEGEHAYDTLSLESSDSMETSISTGGNSACSPDNMSSASGLDMGKIEEMEK 1153
L A +G+ + M+ + S + + S + E EK
Sbjct: 1686 ELKAQMASAGQGKEEAVKQLRKMQAQMKELWREVEETRTSREEIFSQN-------RESEK 1738
Query: 1154 MLKEAHAEKNRLMESREREMELRRQALEEERRRREQVERRLQSESA----RRQ---QLVE 1206
LK AE RL E RRQA ++ ++V S++A +RQ +L +
Sbjct: 1739 RLKGLEAEVLRLQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILEEKRQLEGRLGQ 1798
Query: 1207 KEVKMREKQFSQARPLTRYLPIRKEDFDLKTHIES 1241
E ++ E+Q + RY + + L T + +
Sbjct: 1799 LEEELEEEQSNSELLNDRYRKLLLQVESLTTELSA 1833
Score = 41.2 bits (95), Expect = 0.007
Identities = 64/235 (27%), Positives = 105/235 (44%), Gaps = 20/235 (8%)
Query: 558 VQRKLSSGD-LRVPVTRERKNSITEISD---NEDDLLEYHRRQRQERLREQEMERLERQR 613
+Q +L++ D R ++R E+++ ++ +LE +RQ + RL + E E E Q
Sbjct: 1750 LQEELAASDRARRQAQQDRDEMADEVANGNLSKAAILE-EKRQLEGRLGQLEEELEEEQS 1808
Query: 614 LETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRP-SRGLAGASGRSSEEPGVAT 672
+LN EL S + +A A +GR+ R + GR EE A
Sbjct: 1809 NSELLNDRYRKLLLQVESLTTEL-SAERSFSAKAESGRQQLERQIQELRGRLGEEDAGAR 1867
Query: 673 QR------LWESMERSDEENLKEECSSTESTQQEHEDAPSTKLQGEVLALEEERA---QV 723
R ES EE L++E + + A +L+ VL +EEER Q+
Sbjct: 1868 ARHKMTIAALESKLAQAEEQLEQETRERILSGKLVRRAEK-RLKEVVLQVEEERRVADQL 1926
Query: 724 LGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREAERALLQKEQKAVDQLQE 778
+E+ +RVK+L++QL+E+ EA +A G R +R L + A +E
Sbjct: 1927 RDQLEKGNLRVKQLKRQLEEAEEEASRAQA---GRRRLQRELEDVTESAESMNRE 1978
Score = 32.0 bits (71), Expect = 4.2
Identities = 24/84 (28%), Positives = 43/84 (51%), Gaps = 6/84 (7%)
Query: 1158 AHAEKNR-LMESREREMELRRQALEEERRRREQVERRLQSESARRQQLVEK-----EVKM 1211
A AE+ R + +R++E+EL LE E+ R++Q+E R QQ +++ E +
Sbjct: 962 AEAEETRGRLAARKQELELVVSELEARVGEEEECSRQMQTEKKRLQQHIQELEAHLEAEE 1021
Query: 1212 REKQFSQARPLTRYLPIRKEDFDL 1235
+Q Q +T ++K + DL
Sbjct: 1022 GARQKLQLEKVTTEAKMKKFEEDL 1045
Score = 32.0 bits (71), Expect = 4.2
Identities = 23/89 (25%), Positives = 50/89 (56%), Gaps = 4/89 (4%)
Query: 1147 KIEEMEKMLKEAHAEK---NRLMESREREMELRRQALEEERRRREQVERRLQSESARRQQ 1203
K+ + E+ L++ E+ +L+ E+ ++ +EEERR +Q+ +L+ + R +Q
Sbjct: 1880 KLAQAEEQLEQETRERILSGKLVRRAEKRLKEVVLQVEEERRVADQLRDQLEKGNLRVKQ 1939
Query: 1204 LVEKEVKMREKQFSQARPLTRYLPIRKED 1232
L +++++ E++ S+A+ R L ED
Sbjct: 1940 L-KRQLEEAEEEASRAQAGRRRLQRELED 1967
>gi|122937382 Fas (TNFRSF6) binding factor 1 [Homo sapiens]
Length = 1133
Score = 69.3 bits (168), Expect = 2e-11
Identities = 186/830 (22%), Positives = 311/830 (37%), Gaps = 162/830 (19%)
Query: 208 EPGAAGKKPAATSPLSPMANGGRYLLSPPTS----PGAMSVGSSYENTSPAFSPLSSPAS 263
EPG+ P A+SP+ P G +L P + + + E++ P + PAS
Sbjct: 321 EPGSKQSPPMASSPIQPRKGGADWLGLKDEDLDLFPASPTREAHRESSVPVTPSVPPPAS 380
Query: 264 SGSCASHSPSGQEPGPSVPPLVPARSSSYHLALQPPQSRPSGARSE---SPRLSRKGGHE 320
S +P+G P + PP A S + A Q + R S E S LSRK
Sbjct: 381 QHS----TPAGLPPSRAKPPTEGAGSPAK--ASQASKLRASKEEKEDWLSHALSRKKS-- 432
Query: 321 RPPSPGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVAISLSEYPASGALSQPTSIPG 380
+GL + A T T G P+ + E+ A+G S T+
Sbjct: 433 -------QGLAREQHAGTSEGLHLAGTAGHPPSGSQPLTSTQGLEHAAAGG-SSGTTARE 484
Query: 381 SPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSPSRQLVGRTFSDGLATR---- 436
P +P V SP + + + T SP R G D AT
Sbjct: 485 RPCVRPGVSG-------------SPVTQNHAASALPTGSPKR---GTAPGDLSATEPATC 528
Query: 437 --TLQPPESPRLGRRGLDSMRELPPLSPSLSRRALSPLPTRTTPDPKLNREVAESPRPRR 494
+ Q P P + + PL P R+L LP+ L +V P
Sbjct: 529 FPSTQKPTEPSV---------PVQPLLPESLARSL--LPSTEYQKQLLAAQVQLQCSPAE 577
Query: 495 WAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGSFSGRLSPAYS--LGSLTGASP 552
A + L A+ R+ L A H+ G L + L + A
Sbjct: 578 LQAELLHSQARLAELEAQVRK-------LELERAQHE-LLLGSLQQQHQADLELIESAHR 629
Query: 553 CQSPCVQRKLSSGDLRVPVTRERKNS--ITEISDNEDDLLEYHRRQRQERL------REQ 604
+ ++ + R+ E ++ +++ + E E Q Q RL ++Q
Sbjct: 630 SRIKVLETSYQQREERLRRENEELSARYLSQCQEAEQARAEL-TAQHQRRLAAIAQEKDQ 688
Query: 605 EMERLERQRLETILNLCAEYSRADGGPEAGELPSIGEATAALALAGRRPSRGLAG----- 659
EMERL + +IL++ R D + L + + A + +R L
Sbjct: 689 EMERLRELQRASILDM-----RRDHEEQLQRLKLLKDREVDAATSATSHTRSLNSIIHQM 743
Query: 660 ---ASGRSSEEPGVATQRLWESMERS------DEE---------NLKEECSSTESTQQEH 701
+S V L S ER DE+ + + S QQE
Sbjct: 744 EKFSSSLHELSSRVEASHLTTSQERELGIRQRDEQLRALQERLGQQQRDMEEERSRQQEV 803
Query: 702 EDAPSTKLQGEVLALEEERAQVLGHVEQLKVRVKELEQQLQESAREAEMERALLQGEREA 761
+L + LE+ER +V + + + LE+Q + +A++ MERA E E
Sbjct: 804 IGKMEARLNEQSRLLEQERWRVTAEQSKAESMQRALEEQRKVTAQQMAMERA----ELER 859
Query: 762 ERALLQKEQKAV----DQLQEKLVA------LETGIQKER-DKEAE-ALETETK------ 803
++ L +EQK+V + + +L A + + KER ++EAE AL+ +T+
Sbjct: 860 AKSALLEEQKSVMLKCGEERRRLAAEWAEFSAQQKLSKERAEREAERALQVDTQREGTLI 919
Query: 804 --LFEDLEFQQLERESRVEEERELAGQGLLRSKAELLR--------------SIAKRKER 847
E E + E R EE++ A + L + + LR A+ E
Sbjct: 920 SLAKEQAELKIRASELRAEEKQLAAERAALEQERQELRLEKERINATALRVKLRAEEVES 979
Query: 848 LAILDSQAGQIRAQAVQESERLARDKNASLQLLQKEKEKLTVLERRYHSLTGGRPFPKTT 907
++ + S+ + +A++E++++ ++ A LQ +Q+++E+L E+ H
Sbjct: 980 MSKVASEKYEEGERALREAQQVQAEQQARLQAVQQQQERLRKQEQHMH------------ 1027
Query: 908 STLKEMEKLLLPAVDLEQWYQELMAGL------GTGPAAASPHSSPPPLP 951
+E L + L++ Q+L + L GPAA+S + PP P
Sbjct: 1028 ---QEHLSLAQQRLQLDRARQDLPSSLVGLFPRAQGPAASSQSALMPPAP 1074
Score = 32.0 bits (71), Expect = 4.2
Identities = 25/100 (25%), Positives = 47/100 (47%), Gaps = 21/100 (21%)
Query: 1148 IEEMEKMLKEAH-----AEKNRLMESREREMELRRQA----------------LEEERRR 1186
I +MEK H E + L S+ERE+ +R++ +EEER R
Sbjct: 740 IHQMEKFSSSLHELSSRVEASHLTTSQERELGIRQRDEQLRALQERLGQQQRDMEEERSR 799
Query: 1187 REQVERRLQSESARRQQLVEKEVKMREKQFSQARPLTRYL 1226
+++V ++++ + +L+E+E + S+A + R L
Sbjct: 800 QQEVIGKMEARLNEQSRLLEQERWRVTAEQSKAESMQRAL 839
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 68.2 bits (165), Expect = 5e-11
Identities = 117/451 (25%), Positives = 151/451 (33%), Gaps = 71/451 (15%)
Query: 146 PAGGRAPGPPYSPVPAESESLVNGNHTPQ---TATRGPSACASHSSLVSSIEKDLQEIMD 202
PA P PP + P +S S + + T + A R PSA S +
Sbjct: 192 PAPSARPRPP-TEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLS 250
Query: 203 SLVLEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPAFSPLSSPA 262
S P A G A P P G + L P +P + S SPL++P+
Sbjct: 251 SPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSS--SPLATPS 308
Query: 263 SSGSCASHSPSG--------------QEPGPSVPPLVPARSSSYHLALQPPQSRPSGARS 308
S + S +P P P PP P+ S PP + PS A +
Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPS-PSAPPSLQTLPSPPATPPSQATT 367
Query: 309 ESPRLSRKGGHERPPSPGLRGLLT---DSPAATVLAEARR-------------ATESPRL 352
+ + H PSP L L T +P A L + AT SP+
Sbjct: 368 SLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQA 427
Query: 353 GGQLPVVAISLS-----EYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFR 407
L V + P S P S P SP PP AP + PPSP
Sbjct: 428 PNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPA 487
Query: 408 EPPGSERVLTTSPSRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRELP-------PL 460
PP S + +P Q + L P P L L ++ P P
Sbjct: 488 SPPMSP---SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPF 544
Query: 461 SPSLSRRALSPLPTRTTPDPKLNR----EVAESP-------RPRRWAAHGASPE------ 503
SPS S +SPL T P + +V SP PRR G
Sbjct: 545 SPSAS-LPMSPLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRL 603
Query: 504 DFSLTLGARGRRTRSPSPTL-GESLAPHKGS 533
+L G +RSPS TL G LA H S
Sbjct: 604 TLALAPGPPPPPSRSPSSTLSGPDLAGHSSS 634
Score = 66.6 bits (161), Expect = 2e-10
Identities = 122/441 (27%), Positives = 164/441 (37%), Gaps = 70/441 (15%)
Query: 154 PPYSPVPAESESLVNGNHTPQ----TATRGPSACASHSSL----VSSIEKDLQEIMDSLV 205
PP P ++L + TP T+ P+ A+HS L +S + + +L
Sbjct: 342 PPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALA 401
Query: 206 LEEPGAAGKKPAATSPLSPMANGGRYLLSPPTSPGAMSVGSSYENTSPA--------FSP 257
L P A P A+ PLSP+A P +P A++V SP FSP
Sbjct: 402 LP-PLQAPPSPPASPPLSPLATPS------PQAPNALAVHLLQAPFSPPPSPPVQAPFSP 454
Query: 258 LSSPASSGSCASHS---PSGQEPGPSVPPLVPARSSSYHLALQPPQSRPSGARSESPRLS 314
+SP S S S PS P VPP PA A PPQ+ P A P
Sbjct: 455 PASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAP--PLQL 512
Query: 315 RKGGHERPPS---PGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVAISLSEYP---A 368
K + PP+ P L+ L SP A+ +A SP + +A + P A
Sbjct: 513 AKPPPQAPPALATPPLQAL--PSPPASFPGQA---PFSPSASLPMSPLATPPPQAPPVLA 567
Query: 369 SGALSQPTSIPGSPKFQ----PPVPAPRNKIG----TLQDRPPSPFREPPGSERVLTTSP 420
+ L P S P SP Q PP P P + TL P P PP S SP
Sbjct: 568 APLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP---PPPSR-----SP 619
Query: 421 SRQLVGRTFSDGLATRTLQPPESPRLGRRGLDSMRE-----LPPLSPSLSRRALSPLPTR 475
S L G + ++ T P E RG DS E PP P A P
Sbjct: 620 SSTLSGPDLAGHSSSATSTPEE-----LRGYDSGPEGGAAASPP--PDAELAACHPAAWS 672
Query: 476 TTPDPKLN-REVAESPRPRRWAAHGASPEDFSLTLGARGRRTRSPSPTLGESLAPHKGSF 534
P P L R +P P A S + G + +P+P + P G+
Sbjct: 673 RGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDP-GPSPGTS 731
Query: 535 SGRLSPAYSLGSLTGASPCQS 555
G+ + G+ + SP Q+
Sbjct: 732 GGKAAAGAGAGA-SSRSPKQA 751
Score = 35.0 bits (79), Expect = 0.50
Identities = 72/288 (25%), Positives = 94/288 (32%), Gaps = 53/288 (18%)
Query: 301 SRPSGARSESPRLSRKGGHERPPSPGLRGLLTDSPAATVLAEARRATESPRLGGQLPVVA 360
+R AR+ R G RPP P L AA + A + +GG
Sbjct: 14 ARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGIGG------ 67
Query: 361 ISLSEYPASGALSQPTSIPGSPKFQPPVPAPRNKIGTLQDRPPSPFREPPGSERVLTTSP 420
+ P S + PT G+ P P + G R PP TSP
Sbjct: 68 ---ATIPESAPRAGPTRSAGTSSRNPASRPPASGRGE---------RAPPAK----NTSP 111
Query: 421 SRQLVGRTFSDGLATRTLQPPESPRLGRRGL----------DSMRELPPLSP-SLSRRAL 469
G S G A+ T +P LG++GL E P S S R
Sbjct: 112 -----GPVSSPGRASGTTRPGP---LGQKGLRISAEETVARGKATEAPKRSALSAGARRD 163
Query: 470 SPLPTRTTPDPKLNREVAES------PRPRRWAAHGASPEDFSLTL-GARGRRTRSPSPT 522
+ PT TP P + R + PRP A E ++ A T PSP
Sbjct: 164 TSGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPA 223
Query: 523 LGESLAPHKGSFSGRLSPAYSLGSLTGASPCQSPCVQRKLSSGDLRVP 570
A + S G L S + A+P SP + G R P
Sbjct: 224 -----ARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP 266
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.128 0.364
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 60,152,748
Number of Sequences: 37866
Number of extensions: 3531470
Number of successful extensions: 39277
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 441
Number of HSP's successfully gapped in prelim test: 2231
Number of HSP's that attempted gapping in prelim test: 19209
Number of HSP's gapped (non-prelim): 15704
length of query: 1377
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1262
effective length of database: 13,892,928
effective search space: 17532875136
effective search space used: 17532875136
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.