Search of human proteins with 34577063

Search of human proteins with 34577063

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|34577063 adenylosuccinate synthase [Homo sapiens]
         (456 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|34577063 adenylosuccinate synthase [Homo sapiens]                  926   0.0  
gi|22748717 adenylosuccinate synthase like 1 isoform 2 [Homo sap...   715   0.0  
gi|40316944 adenylosuccinate synthase like 1 isoform 1 [Homo sap...   652   0.0  
gi|42491362 IKK interacting protein isoform 2 [Homo sapiens]           35   0.14 
gi|6005701 ATP-binding cassette, sub-family A member 8 [Homo sap...    31   2.7  
gi|8922665 pantothenate kinase 4 [Homo sapiens]                        29   7.7  

>gi|34577063 adenylosuccinate synthase [Homo sapiens]
          Length = 456

 Score =  926 bits (2392), Expect = 0.0
 Identities = 456/456 (100%), Positives = 456/456 (100%)

Query: 1   MAFAETYPAASSLPNGDCGRPRARPGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRC 60
           MAFAETYPAASSLPNGDCGRPRARPGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRC
Sbjct: 1   MAFAETYPAASSLPNGDCGRPRARPGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRC 60

Query: 61  QGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGL 120
           QGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGL
Sbjct: 61  QGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGL 120

Query: 121 EGWEKRLIISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLR 180
           EGWEKRLIISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLR
Sbjct: 121 EGWEKRLIISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLR 180

Query: 181 MCDLVSDFDGFSERFKVLANQYKSIYPTLEIDIEGELQKLKGYMEKIKPMVRDGVYFLYE 240
           MCDLVSDFDGFSERFKVLANQYKSIYPTLEIDIEGELQKLKGYMEKIKPMVRDGVYFLYE
Sbjct: 181 MCDLVSDFDGFSERFKVLANQYKSIYPTLEIDIEGELQKLKGYMEKIKPMVRDGVYFLYE 240

Query: 241 ALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAY 300
           ALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAY
Sbjct: 241 ALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAY 300

Query: 301 TTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALAL 360
           TTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALAL
Sbjct: 301 TTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALAL 360

Query: 361 TKLDILDMFTEIKVGVAYKLDGEIIPHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKE 420
           TKLDILDMFTEIKVGVAYKLDGEIIPHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKE
Sbjct: 361 TKLDILDMFTEIKVGVAYKLDGEIIPHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKE 420

Query: 421 LPVNAQNYVRFIEDELQIPVKWIGVGKSRESMIQLF 456
           LPVNAQNYVRFIEDELQIPVKWIGVGKSRESMIQLF
Sbjct: 421 LPVNAQNYVRFIEDELQIPVKWIGVGKSRESMIQLF 456


>gi|22748717 adenylosuccinate synthase like 1 isoform 2 [Homo
           sapiens]
          Length = 457

 Score =  715 bits (1846), Expect = 0.0
 Identities = 347/454 (76%), Positives = 399/454 (87%), Gaps = 8/454 (1%)

Query: 9   AASSLPNGDCGRPRAR------PGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQG 62
           A++  P G  G  R R        G+RVTVVLGAQWGDEGKGKVVDLLA DADI+ RCQG
Sbjct: 6   ASNDRPPGAGGVKRGRLQQEAAATGSRVTVVLGAQWGDEGKGKVVDLLATDADIISRCQG 65

Query: 63  GNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLEG 122
           GNNAGHTVVVD  EYDFHLLPSGIIN    +FIGNGVVIHLPGLFEEAEKN +KG  L+ 
Sbjct: 66  GNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKG--LKD 123

Query: 123 WEKRLIISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMC 182
           WEKRLIISDRAH+VFDFHQA DG+QE QRQ Q GKN+GTTKKGIGP YSSKAAR+GLR+C
Sbjct: 124 WEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRIC 183

Query: 183 DLVSDFDGFSERFKVLANQYKSIYPTLEIDIEGELQKLKGYMEKIKPMVRDGVYFLYEAL 242
           DL+SDFD FS RFK LA+Q++S++PTLEIDIEG+L++LKG+ E+I+PMVRDGVYF+YEAL
Sbjct: 184 DLLSDFDEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEAL 243

Query: 243 HGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTT 302
           HGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLG+PPQN+G+VYGVVKAYTT
Sbjct: 244 HGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTT 303

Query: 303 RVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALALTK 362
           RVGIGAFPTEQ NEIG LLQTRG E+GVTTGRKRRCGWLDL++L+YAHM+NGFTALALTK
Sbjct: 304 RVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTK 363

Query: 363 LDILDMFTEIKVGVAYKLDGEIIPHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKELP 422
           LDILD+  E+KVGV+YKL+G+ IP+ PANQE+L KVEV+Y+TLPGW  D + AR +++LP
Sbjct: 364 LDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLP 423

Query: 423 VNAQNYVRFIEDELQIPVKWIGVGKSRESMIQLF 456
             AQNY+RF+E+ + + VKW+GVGKSRESMIQLF
Sbjct: 424 PQAQNYIRFVENHVGVAVKWVGVGKSRESMIQLF 457


>gi|40316944 adenylosuccinate synthase like 1 isoform 1 [Homo
           sapiens]
          Length = 500

 Score =  652 bits (1681), Expect = 0.0
 Identities = 310/396 (78%), Positives = 359/396 (90%), Gaps = 2/396 (0%)

Query: 61  QGGNNAGHTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGL 120
           +GGNNAGHTVVVD  EYDFHLLPSGIIN    +FIGNGVVIHLPGLFEEAEKN +KG  L
Sbjct: 107 RGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKG--L 164

Query: 121 EGWEKRLIISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLR 180
           + WEKRLIISDRAH+VFDFHQA DG+QE QRQ Q GKN+GTTKKGIGP YSSKAAR+GLR
Sbjct: 165 KDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLR 224

Query: 181 MCDLVSDFDGFSERFKVLANQYKSIYPTLEIDIEGELQKLKGYMEKIKPMVRDGVYFLYE 240
           +CDL+SDFD FS RFK LA+Q++S++PTLEIDIEG+L++LKG+ E+I+PMVRDGVYF+YE
Sbjct: 225 ICDLLSDFDEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYE 284

Query: 241 ALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAY 300
           ALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLG+PPQN+G+VYGVVKAY
Sbjct: 285 ALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAY 344

Query: 301 TTRVGIGAFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALAL 360
           TTRVGIGAFPTEQ NEIG LLQTRG E+GVTTGRKRRCGWLDL++L+YAHM+NGFTALAL
Sbjct: 345 TTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALAL 404

Query: 361 TKLDILDMFTEIKVGVAYKLDGEIIPHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKE 420
           TKLDILD+  E+KVGV+YKL+G+ IP+ PANQE+L KVEV+Y+TLPGW  D + AR +++
Sbjct: 405 TKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWED 464

Query: 421 LPVNAQNYVRFIEDELQIPVKWIGVGKSRESMIQLF 456
           LP  AQNY+RF+E+ + + VKW+GVGKSRESMIQLF
Sbjct: 465 LPPQAQNYIRFVENHVGVAVKWVGVGKSRESMIQLF 500


>gi|42491362 IKK interacting protein isoform 2 [Homo sapiens]
          Length = 350

 Score = 35.0 bits (79), Expect = 0.14
 Identities = 34/146 (23%), Positives = 63/146 (43%), Gaps = 23/146 (15%)

Query: 108 EEAEKNVQKGKGLEGWEKRLIISDRAHIVFDFHQAADGIQEQQRQ-EQAGKNLGTTKKGI 166
           +++  ++ K  GL+    +  I   + +V D     D +QE + + E+  KN   T K I
Sbjct: 158 DQSTTSMAKDVGLKITSVKTDIRRISGLVTDVISLTDSVQELENKIEKVEKN---TVKNI 214

Query: 167 GPVYSSKAARSGL-----------------RMCDLVSDFDGFSERFKVLANQYKSIYPTL 209
           G + SS   R+                    + +L SDFD  ++RF  L      +  T+
Sbjct: 215 GDLLSSSIDRTATLRKTASENSQRINSVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTV 274

Query: 210 EI--DIEGELQKLKGYMEKIKPMVRD 233
               D++ ++  LK    +++P+V D
Sbjct: 275 TFANDLKPKVYNLKKDFSRLEPLVND 300


>gi|6005701 ATP-binding cassette, sub-family A member 8 [Homo
           sapiens]
          Length = 1581

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 17/58 (29%), Positives = 28/58 (48%), Gaps = 6/58 (10%)

Query: 341 LDLVLLKYAHMINGFTALALTKLDILDMFTEIKVGVAYKLDGEIIPHIPANQEVLNKV 398
           L L +  ++H +N F++L    L  +D F E +  V Y       P     Q+++NKV
Sbjct: 42  LCLYIYPHSHQVNDFSSLLTMDLGRVDTFNESRFSVVY------TPVTNTTQQIMNKV 93


>gi|8922665 pantothenate kinase 4 [Homo sapiens]
          Length = 773

 Score = 29.3 bits (64), Expect = 7.7
 Identities = 19/67 (28%), Positives = 34/67 (50%), Gaps = 1/67 (1%)

Query: 203 KSIYPTLEIDIEGELQKLKGYMEKIKPMVRDGVYFLYEALHGPPKKILVEGANAALLDID 262
           K++   LE D     ++ K  +++ +P + D      + L GPP K  +  A+ + +DI 
Sbjct: 572 KAVSAVLESDPYFGFEEAKRKLQE-RPWLVDSYSEWLQRLKGPPHKCALIFADNSGIDII 630

Query: 263 FGTYPFV 269
            G +PFV
Sbjct: 631 LGVFPFV 637


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.139    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,441,455
Number of Sequences: 37866
Number of extensions: 795849
Number of successful extensions: 1581
Number of sequences better than 10.0: 6
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 1576
Number of HSP's gapped (non-prelim): 6
length of query: 456
length of database: 18,247,518
effective HSP length: 106
effective length of query: 350
effective length of database: 14,233,722
effective search space: 4981802700
effective search space used: 4981802700
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.