Guide to the Human Genome
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Search of human proteins with 33598968

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens]
         (1349 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens]               2694   0.0  
gi|221316634 LIM domain only 7 isoform 2 [Homo sapiens]              1805   0.0  
gi|163310745 LIM and calponin homology domains 1 isoform c [Homo...   451   e-126
gi|163310743 LIM and calponin homology domains 1 isoform b [Homo...   442   e-123
gi|163310741 LIM and calponin homology domains 1 isoform a [Homo...   442   e-123
gi|163310747 LIM and calponin homology domains 1 isoform d [Homo...   290   5e-78
gi|163310749 LIM and calponin homology domains 1 isoform e [Homo...   289   1e-77
gi|148746195 trichohyalin [Homo sapiens]                               80   1e-14
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li...    77   9e-14
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa...    75   3e-13
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m...    74   9e-13
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m...    74   9e-13
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    74   1e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    73   2e-12
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi...    69   2e-11
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]                       69   2e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    67   9e-11
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa...    67   1e-10
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]        67   2e-10
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]            66   3e-10
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]             66   3e-10
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ...    65   3e-10
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [...    65   3e-10
gi|55741709 RNA binding motif protein 25 [Homo sapiens]                65   4e-10
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]            64   8e-10
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ...    64   1e-09
gi|4503509 eukaryotic translation initiation factor 3, subunit 1...    63   2e-09
gi|4502923 calponin 3 [Homo sapiens]                                   62   3e-09
gi|102467242 inner centromere protein antigens 135/155kDa isofor...    62   3e-09
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap...    62   5e-09

>gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens]
          Length = 1349

 Score = 2694 bits (6982), Expect = 0.0
 Identities = 1349/1349 (100%), Positives = 1349/1349 (100%)

Query: 1    MKKIRICHIFTFYSWMSYDVLFQRTELGALEIWRQLICAHVCICVGWLYLRDRVCSKKDI 60
            MKKIRICHIFTFYSWMSYDVLFQRTELGALEIWRQLICAHVCICVGWLYLRDRVCSKKDI
Sbjct: 1    MKKIRICHIFTFYSWMSYDVLFQRTELGALEIWRQLICAHVCICVGWLYLRDRVCSKKDI 60

Query: 61   ILRTEQNSGRTILIKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIA 120
            ILRTEQNSGRTILIKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIA
Sbjct: 61   ILRTEQNSGRTILIKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIA 120

Query: 121  GLDNINVFLKACEQIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKA 180
            GLDNINVFLKACEQIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKA
Sbjct: 121  GLDNINVFLKACEQIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKA 180

Query: 181  QSNPYYNGPHLNLKAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRH 240
            QSNPYYNGPHLNLKAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRH
Sbjct: 181  QSNPYYNGPHLNLKAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRH 240

Query: 241  HKREDSFESLDSLGSRSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRIS 300
            HKREDSFESLDSLGSRSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRIS
Sbjct: 241  HKREDSFESLDSLGSRSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRIS 300

Query: 301  AVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQ 360
            AVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQ
Sbjct: 301  AVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQ 360

Query: 361  KIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTS 420
            KIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTS
Sbjct: 361  KIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTS 420

Query: 421  DLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGK 480
            DLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGK
Sbjct: 421  DLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGK 480

Query: 481  RPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSP 540
            RPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSP
Sbjct: 481  RPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSP 540

Query: 541  ASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMD 600
            ASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMD
Sbjct: 541  ASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMD 600

Query: 601  DAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFS 660
            DAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFS
Sbjct: 601  DAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFS 660

Query: 661  SLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLD 720
            SLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLD
Sbjct: 661  SLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLD 720

Query: 721  FGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQET 780
            FGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQET
Sbjct: 721  FGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQET 780

Query: 781  GHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIH 840
            GHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIH
Sbjct: 781  GHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIH 840

Query: 841  DESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQ 900
            DESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQ
Sbjct: 841  DESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQ 900

Query: 901  ERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREP 960
            ERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREP
Sbjct: 901  ERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREP 960

Query: 961  SLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQL 1020
            SLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQL
Sbjct: 961  SLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQL 1020

Query: 1021 QEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFL 1080
            QEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFL
Sbjct: 1021 QEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFL 1080

Query: 1081 PGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEM 1140
            PGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEM
Sbjct: 1081 PGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEM 1140

Query: 1141 RKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGF 1200
            RKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGF
Sbjct: 1141 RKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGF 1200

Query: 1201 YASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSP 1260
            YASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSP
Sbjct: 1201 YASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSP 1260

Query: 1261 SASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSS 1320
            SASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSS
Sbjct: 1261 SASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSS 1320

Query: 1321 SGAEVRIRNHQLYCNDCYLRFKSGRPTAM 1349
            SGAEVRIRNHQLYCNDCYLRFKSGRPTAM
Sbjct: 1321 SGAEVRIRNHQLYCNDCYLRFKSGRPTAM 1349


>gi|221316634 LIM domain only 7 isoform 2 [Homo sapiens]
          Length = 1385

 Score = 1805 bits (4676), Expect = 0.0
 Identities = 930/981 (94%), Positives = 939/981 (95%), Gaps = 12/981 (1%)

Query: 291  KDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTE 350
            KDDM  R+I + +  T +P            S+ P P  +    + E  R   AS +  +
Sbjct: 352  KDDMLTRKIQSWKLGTTVP----------PISFTPGPCSEADLKRWEAIRE--ASRLRHK 399

Query: 351  ADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK 410
                  RLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK
Sbjct: 400  KRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK 459

Query: 411  WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMY 470
            WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMY
Sbjct: 460  WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMY 519

Query: 471  SFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLP 530
            SFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLP
Sbjct: 520  SFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLP 579

Query: 531  SQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGI 590
            SQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGI
Sbjct: 580  SQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGI 639

Query: 591  SSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVT 650
            SSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVT
Sbjct: 640  SSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVT 699

Query: 651  RLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRIS 710
            RLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRIS
Sbjct: 700  RLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRIS 759

Query: 711  INQTPGKSLDFGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEW 770
            INQTPGKSLDFGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEW
Sbjct: 760  INQTPGKSLDFGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEW 819

Query: 771  EEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSN 830
            EEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSN
Sbjct: 820  EEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSN 879

Query: 831  IESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWV 890
            IESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWV
Sbjct: 880  IESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWV 939

Query: 891  WDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS 950
            WDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS
Sbjct: 940  WDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS 999

Query: 951  NSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVI 1010
            NSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVI
Sbjct: 1000 NSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVI 1059

Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1070
            ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP
Sbjct: 1060 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1119

Query: 1071 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAE 1130
            KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAE
Sbjct: 1120 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAE 1179

Query: 1131 LERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQ 1190
            LERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQ
Sbjct: 1180 LERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQ 1239

Query: 1191 PPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATT 1250
            PPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATT
Sbjct: 1240 PPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATT 1299

Query: 1251 QSPTPRSHSPSASQSGSQLRN 1271
            QSPTPRSHSPSASQSGSQLRN
Sbjct: 1300 QSPTPRSHSPSASQSGSQLRN 1320



 Score =  157 bits (396), Expect = 9e-38
 Identities = 74/81 (91%), Positives = 77/81 (95%)

Query: 286 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 345
           MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS
Sbjct: 1   MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 60

Query: 346 PVYTEADGTFSRLFQKIYGEN 366
           PVYTEADGTFS   ++I+G N
Sbjct: 61  PVYTEADGTFSSNQRRIWGTN 81


>gi|163310745 LIM and calponin homology domains 1 isoform c [Homo
            sapiens]
          Length = 1056

 Score =  451 bits (1160), Expect = e-126
 Identities = 329/984 (33%), Positives = 507/984 (51%), Gaps = 144/984 (14%)

Query: 74   IKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIAGLDNINVFLKACE 133
            I+ VT ++F  KDFR  LENG+LLC+L+N +KPG++KKINRL TPIAGLDNI +FL+ C+
Sbjct: 31   IEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCK 90

Query: 134  QIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKAQSNPYYNGPHLNL 193
            ++GLKE+QLF P DLQD SNRVTVK  +  R++KNVL+T+YWLG+ A S   Y+G  LNL
Sbjct: 91   ELGLKESQLFDPSDLQDTSNRVTVKSLDYSRKLKNVLVTIYWLGKAANSCTSYSGTTLNL 150

Query: 194  KAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRHHKREDSFESLDSL 253
            K FE LL Q + K  +D    KRS RDSGY D W  ER + L+PPR H R+DSF+SLDS 
Sbjct: 151  KEFEGLLAQ-MRKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPR-HGRDDSFDSLDSF 208

Query: 254  GSRSLTSCSSDITLRGGREGFESDTDSEFTF-KMQDYNKDDMSYRRISAVEPKTALPFNR 312
            GSRS  + S D+ LRG  +G  SD++S+    K+ D  KDDMS RR S  EPK+A+PFN+
Sbjct: 209  GSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQ 268

Query: 313  FLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWA---SPVYTEADGTFSRLFQKIYGENGSK 369
            +LPNKS Q +YVPAPLRKKK ++ E+ R+SW+   SP+  E    +      +  +  S 
Sbjct: 269  YLPNKSNQTAYVPAPLRKKKAER-EEYRKSWSTATSPLGGERPFRYGPR-TPVSDDAEST 326

Query: 370  SMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKK 426
            SM D+  E+   VQ   + R E++Q I +QL+E+D KWQDDLA+WK RR+S + DL KK+
Sbjct: 327  SMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKE 386

Query: 427  EEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK--STVPSRRRMYSFDDVLEEG 479
            EER+++EK         + ++S KT++E++Q++E + ++      + R     + +L++ 
Sbjct: 387  EERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ- 445

Query: 480  KRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQS 539
                  T+SEA    ER+E       S   + + ++F    + +     L  QS    + 
Sbjct: 446  -YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLNDPNPMK---YLRQQSLPPPKF 499

Query: 540  PASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTM 599
             A++ +  +R++ ++++  + S   S  KT T +   ++TP+P+ SQ +    + +++ +
Sbjct: 500  TATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPMLTPKPY-SQPKNSQDVLKTFKV 556

Query: 600  DDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPF 659
            D     NG                                 E    EE+  R     +P 
Sbjct: 557  DGKVSVNG---------------------------------ETVHREEEKERECPTVAPA 583

Query: 660  SSLSQDQAATSKATLSSTSGLDLMSESGEGEI------SPQREVSRSQDQFSDMRISINQ 713
             SL++ Q     A +   S L+L  ++G  EI      S  +E++ + ++          
Sbjct: 584  HSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKN 642

Query: 714  TPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVDDEIIAINNTKFSYNDSKEWEE 772
              GKS      +    P  F  +V   SP   F +     +   + N      D K+ E 
Sbjct: 643  DGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQ---LKNDVSEEKDQKKPEN 699

Query: 773  AMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIE 832
             M+   E   LV+  ++  K  SPE +                 ++T  F + +  +N  
Sbjct: 700  EMSGKVE---LVLS-QKVVKPKSPEPE----------------ATLTFPFLDKMPEAN-- 737

Query: 833  SKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWD 892
                                 + L NL   SQ     S  S       P ++    W WD
Sbjct: 738  --------------------QLHLPNL--NSQVDSPSSEKS-------PVMTPFKFWAWD 768

Query: 893  QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNS 952
             EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A++E E E  +Y +EE  ++    
Sbjct: 769  PEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTV 828

Query: 953  MSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIER 1012
            +  T                S S+D+  T +   E      ++   D G   QD+   ++
Sbjct: 829  VPFTV--------------SSSSADQLSTSSSMTEGSGTMNKI---DLG-NCQDE---KQ 867

Query: 1013 ERKWEQQLQEEQEQKRLQAEAEEQ 1036
            +R+W++  Q +     L+    ++
Sbjct: 868  DRRWKKSFQGDDSDLLLKTRESDR 891



 Score =  113 bits (282), Expect = 1e-24
 Identities = 101/343 (29%), Positives = 160/343 (46%), Gaps = 60/343 (17%)

Query: 1011 ERERKWEQQLQEEQE---QKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSY 1067
            E ER+ +++ Q+EQE   Q+R Q E ++ K   E +K Q E+E E      + R+ ++  
Sbjct: 770  EEERRRQEKWQQEQERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDT 827

Query: 1068 DIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPS 1127
             +P T  +SS     D+  + S+       T  +G    +D +GN               
Sbjct: 828  VVPFTVSSSS----ADQLSTSSS------MTEGSGTMNKID-LGNC-------------- 862

Query: 1128 GAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNS 1187
                  Q   Q+ R +     D+S +  ++   ++  +   G +  G +L +  +P S  
Sbjct: 863  ------QDEKQDRRWKKSFQGDDSDLLLKTRESDR--LEEKGSLTEG-ALAHSGNPVSKG 913

Query: 1188 WRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGV 1247
              +   L+   G     +    ++ P Q   TSN           P  S+  VK  T  +
Sbjct: 914  VHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN-----------PTHSSEDVKPKT--L 960

Query: 1248 ATTQSPTPRSHSPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCF 1307
               +S   +  SPS        R +S+SGK++CS C   LGKGAAMIIE+L L +H+ CF
Sbjct: 961  PLDKSINHQIESPSE-------RRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCF 1013

Query: 1308 KCVACECDLGGSSSGAEVRIRNHQLYCNDCYLRFKS-GRPTAM 1349
            +C  C+  LG + SG +VRIRN  L CNDCY+R +S G+PT +
Sbjct: 1014 RCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1056



 Score = 31.6 bits (70), Expect = 5.4
 Identities = 58/271 (21%), Positives = 102/271 (37%), Gaps = 39/271 (14%)

Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1070
            E    ++ + +EE   +      +EQ +    Q R+ + + +  +  ++ RR   S D+ 
Sbjct: 324  ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 383

Query: 1071 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1129
            K EE        +R K       +D ++ +  + K   +I      + R   E   +  +
Sbjct: 384  KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 435

Query: 1130 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1188
            + E + ILQ+  +R  +           +    E + +P I+ R  S + NL S      
Sbjct: 436  QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 478

Query: 1189 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1246
                +LN P        ++  S PPP+  +T      R     +S+   S    KT T  
Sbjct: 479  ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 531

Query: 1247 VATTQSPTPRSHSPSASQSGSQLRNRSVSGK 1277
                 +P P S  P  SQ    L+   V GK
Sbjct: 532  AVPMLTPKPYS-QPKNSQ--DVLKTFKVDGK 559


>gi|163310743 LIM and calponin homology domains 1 isoform b [Homo
            sapiens]
          Length = 1057

 Score =  442 bits (1137), Expect = e-123
 Identities = 331/986 (33%), Positives = 507/986 (51%), Gaps = 147/986 (14%)

Query: 74   IKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIAGLDNINVFLKACE 133
            I+ VT ++F  KDFR  LENG+LLC+L+N +KPG++KKINRL TPIAGLDNI +FL+ C+
Sbjct: 31   IEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCK 90

Query: 134  QIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKAQSNPYYNGPHLNL 193
            ++GLKE+QLF P DLQD SNRVTVK  +  R++KNVL+T+YWLG+ A S   Y+G  LNL
Sbjct: 91   ELGLKESQLFDPSDLQDTSNRVTVKSLDYSRKLKNVLVTIYWLGKAANSCTSYSGTTLNL 150

Query: 194  KAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRHHKREDSFESLDSL 253
            K FE LL Q + K  +D    KRS RDSGY D W  ER + L+PPR H R+DSF+SLDS 
Sbjct: 151  KEFEGLLAQ-MRKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPR-HGRDDSFDSLDSF 208

Query: 254  GSRSLTSCSSDITLRGGREGFESDTDSEFTF-KMQDYNKDDMSYRRISAVEPKTALPFNR 312
            GSRS  + S D+ LRG  +G  SD++S+    K+ D  KDDMS RR S  EPK+A+PFN+
Sbjct: 209  GSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQ 268

Query: 313  FLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWA---SPVYTEADGTFSRLFQKIYGENGSK 369
            +LPNKS Q +YVPAPLRKKK ++ E+ R+SW+   SP+  E    +      +  +  S 
Sbjct: 269  YLPNKSNQTAYVPAPLRKKKAER-EEYRKSWSTATSPLGGERPFRYGPR-TPVSDDAEST 326

Query: 370  SMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKK 426
            SM D+  E+   VQ   + R E++Q I +QL+E+D KWQDDLA+WK RR+S + DL KK+
Sbjct: 327  SMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKE 386

Query: 427  EEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK--STVPSRRRMYSFDDVLEEG 479
            EER+++EK         + ++S KT++E++Q++E + ++      + R     + +L++ 
Sbjct: 387  EERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ- 445

Query: 480  KRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQS 539
                  T+SEA    ER+E       S   + + ++F    + +     L  QS    + 
Sbjct: 446  -YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLNDPNPMK---YLRQQSLPPPKF 499

Query: 540  PASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTM 599
             A++ +  +R++ ++++  + S   S  KT T +   ++TP+P+ SQ +    + +++ +
Sbjct: 500  TATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPMLTPKPY-SQPKNSQDVLKTFKV 556

Query: 600  DDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPF 659
            D     NG                                 E    EE+  R     +P 
Sbjct: 557  DGKVSVNG---------------------------------ETVHREEEKERECPTVAPA 583

Query: 660  SSLSQDQAATSKATLSSTSGLDLMSESGEGEI------SPQREVSRSQDQFSDMRISINQ 713
             SL++ Q     A +   S L+L  ++G  EI      S  +E++ + ++          
Sbjct: 584  HSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKN 642

Query: 714  TPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVDDEIIAINNTKFSYNDSKEWEE 772
              GKS      +    P  F  +V   SP   F +     +   + N      D K+ E 
Sbjct: 643  DGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQ---LKNDVSEEKDQKKPEN 699

Query: 773  AMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIE 832
             M+   E   LV+  ++  K  SPE +                 ++T  F + +  +N  
Sbjct: 700  EMSGKVE---LVLS-QKVVKPKSPEPE----------------ATLTFPFLDKMPEAN-- 737

Query: 833  SKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVW- 891
                                 + L NL   SQ     S  S     PV T   P    W 
Sbjct: 738  --------------------QLHLPNL--NSQVDSPSSEKS-----PVMT---PQFKFWA 767

Query: 892  -DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS 950
             D EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A++E E E  +Y +EE  ++  
Sbjct: 768  WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 827

Query: 951  NSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVI 1010
              +  T                S S+D+  T +   E      ++   D G   QD+   
Sbjct: 828  TVVPFTV--------------SSSSADQLSTSSSMTEGSGTMNKI---DLG-NCQDE--- 866

Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQ 1036
            +++R+W++  Q +     L+    ++
Sbjct: 867  KQDRRWKKSFQGDDSDLLLKTRESDR 892



 Score =  113 bits (282), Expect = 1e-24
 Identities = 101/343 (29%), Positives = 160/343 (46%), Gaps = 60/343 (17%)

Query: 1011 ERERKWEQQLQEEQE---QKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSY 1067
            E ER+ +++ Q+EQE   Q+R Q E ++ K   E +K Q E+E E      + R+ ++  
Sbjct: 771  EEERRRQEKWQQEQERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDT 828

Query: 1068 DIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPS 1127
             +P T  +SS     D+  + S+       T  +G    +D +GN               
Sbjct: 829  VVPFTVSSSS----ADQLSTSSS------MTEGSGTMNKID-LGNC-------------- 863

Query: 1128 GAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNS 1187
                  Q   Q+ R +     D+S +  ++   ++  +   G +  G +L +  +P S  
Sbjct: 864  ------QDEKQDRRWKKSFQGDDSDLLLKTRESDR--LEEKGSLTEG-ALAHSGNPVSKG 914

Query: 1188 WRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGV 1247
              +   L+   G     +    ++ P Q   TSN           P  S+  VK  T  +
Sbjct: 915  VHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN-----------PTHSSEDVKPKT--L 961

Query: 1248 ATTQSPTPRSHSPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCF 1307
               +S   +  SPS        R +S+SGK++CS C   LGKGAAMIIE+L L +H+ CF
Sbjct: 962  PLDKSINHQIESPSE-------RRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCF 1014

Query: 1308 KCVACECDLGGSSSGAEVRIRNHQLYCNDCYLRFKS-GRPTAM 1349
            +C  C+  LG + SG +VRIRN  L CNDCY+R +S G+PT +
Sbjct: 1015 RCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1057



 Score = 31.6 bits (70), Expect = 5.4
 Identities = 58/271 (21%), Positives = 102/271 (37%), Gaps = 39/271 (14%)

Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1070
            E    ++ + +EE   +      +EQ +    Q R+ + + +  +  ++ RR   S D+ 
Sbjct: 324  ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 383

Query: 1071 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1129
            K EE        +R K       +D ++ +  + K   +I      + R   E   +  +
Sbjct: 384  KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 435

Query: 1130 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1188
            + E + ILQ+  +R  +           +    E + +P I+ R  S + NL S      
Sbjct: 436  QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 478

Query: 1189 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1246
                +LN P        ++  S PPP+  +T      R     +S+   S    KT T  
Sbjct: 479  ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 531

Query: 1247 VATTQSPTPRSHSPSASQSGSQLRNRSVSGK 1277
                 +P P S  P  SQ    L+   V GK
Sbjct: 532  AVPMLTPKPYS-QPKNSQ--DVLKTFKVDGK 559


>gi|163310741 LIM and calponin homology domains 1 isoform a [Homo
            sapiens]
          Length = 1083

 Score =  442 bits (1137), Expect = e-123
 Identities = 331/986 (33%), Positives = 507/986 (51%), Gaps = 147/986 (14%)

Query: 74   IKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIAGLDNINVFLKACE 133
            I+ VT ++F  KDFR  LENG+LLC+L+N +KPG++KKINRL TPIAGLDNI +FL+ C+
Sbjct: 31   IEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCK 90

Query: 134  QIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKAQSNPYYNGPHLNL 193
            ++GLKE+QLF P DLQD SNRVTVK  +  R++KNVL+T+YWLG+ A S   Y+G  LNL
Sbjct: 91   ELGLKESQLFDPSDLQDTSNRVTVKSLDYSRKLKNVLVTIYWLGKAANSCTSYSGTTLNL 150

Query: 194  KAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRHHKREDSFESLDSL 253
            K FE LL Q + K  +D    KRS RDSGY D W  ER + L+PPR H R+DSF+SLDS 
Sbjct: 151  KEFEGLLAQ-MRKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPR-HGRDDSFDSLDSF 208

Query: 254  GSRSLTSCSSDITLRGGREGFESDTDSEFTF-KMQDYNKDDMSYRRISAVEPKTALPFNR 312
            GSRS  + S D+ LRG  +G  SD++S+    K+ D  KDDMS RR S  EPK+A+PFN+
Sbjct: 209  GSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQ 268

Query: 313  FLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWA---SPVYTEADGTFSRLFQKIYGENGSK 369
            +LPNKS Q +YVPAPLRKKK ++ E+ R+SW+   SP+  E    +      +  +  S 
Sbjct: 269  YLPNKSNQTAYVPAPLRKKKAER-EEYRKSWSTATSPLGGERPFRYGPR-TPVSDDAEST 326

Query: 370  SMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKK 426
            SM D+  E+   VQ   + R E++Q I +QL+E+D KWQDDLA+WK RR+S + DL KK+
Sbjct: 327  SMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKE 386

Query: 427  EEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK--STVPSRRRMYSFDDVLEEG 479
            EER+++EK         + ++S KT++E++Q++E + ++      + R     + +L++ 
Sbjct: 387  EERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ- 445

Query: 480  KRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQS 539
                  T+SEA    ER+E       S   + + ++F    + +     L  QS    + 
Sbjct: 446  -YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLNDPNPMK---YLRQQSLPPPKF 499

Query: 540  PASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTM 599
             A++ +  +R++ ++++  + S   S  KT T +   ++TP+P+ SQ +    + +++ +
Sbjct: 500  TATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPMLTPKPY-SQPKNSQDVLKTFKV 556

Query: 600  DDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPF 659
            D     NG                                 E    EE+  R     +P 
Sbjct: 557  DGKVSVNG---------------------------------ETVHREEEKERECPTVAPA 583

Query: 660  SSLSQDQAATSKATLSSTSGLDLMSESGEGEI------SPQREVSRSQDQFSDMRISINQ 713
             SL++ Q     A +   S L+L  ++G  EI      S  +E++ + ++          
Sbjct: 584  HSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKN 642

Query: 714  TPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVDDEIIAINNTKFSYNDSKEWEE 772
              GKS      +    P  F  +V   SP   F +     +   + N      D K+ E 
Sbjct: 643  DGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQ---LKNDVSEEKDQKKPEN 699

Query: 773  AMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIE 832
             M+   E   LV+  ++  K  SPE +                 ++T  F + +  +N  
Sbjct: 700  EMSGKVE---LVLS-QKVVKPKSPEPE----------------ATLTFPFLDKMPEAN-- 737

Query: 833  SKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVW- 891
                                 + L NL   SQ     S  S     PV T   P    W 
Sbjct: 738  --------------------QLHLPNL--NSQVDSPSSEKS-----PVMT---PQFKFWA 767

Query: 892  -DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS 950
             D EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A++E E E  +Y +EE  ++  
Sbjct: 768  WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 827

Query: 951  NSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVI 1010
              +  T                S S+D+  T +   E      ++   D G   QD+   
Sbjct: 828  TVVPFTV--------------SSSSADQLSTSSSMTEGSGTMNKI---DLG-NCQDE--- 866

Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQ 1036
            +++R+W++  Q +     L+    ++
Sbjct: 867  KQDRRWKKSFQGDDSDLLLKTRESDR 892



 Score =  123 bits (308), Expect = 1e-27
 Identities = 101/349 (28%), Positives = 161/349 (46%), Gaps = 46/349 (13%)

Query: 1011 ERERKWEQQLQEEQE---QKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSY 1067
            E ER+ +++ Q+EQE   Q+R Q E ++ K   E +K Q E+E E      + R+ ++  
Sbjct: 771  EEERRRQEKWQQEQERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDT 828

Query: 1068 DIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPS 1127
             +P T  +SS     D+  + S+       T  +G    +D +GN               
Sbjct: 829  VVPFTVSSSS----ADQLSTSSS------MTEGSGTMNKID-LGNC-------------- 863

Query: 1128 GAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNS 1187
                  Q   Q+ R +     D+S +  ++   ++  +   G +  G +L +  +P S  
Sbjct: 864  ------QDEKQDRRWKKSFQGDDSDLLLKTRESDR--LEEKGSLTEG-ALAHSGNPVSKG 914

Query: 1188 WRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGV 1247
              +   L+   G     +    ++ P Q   TSN  +          P   S+       
Sbjct: 915  VHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESP 974

Query: 1248 ATTQSPTPRSH------SPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLC 1301
            +  +  +PR H      SP +     Q  NRS+SGK++CS C   LGKGAAMIIE+L L 
Sbjct: 975  SERRKKSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLY 1034

Query: 1302 YHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLRFKS-GRPTAM 1349
            +H+ CF+C  C+  LG + SG +VRIRN  L CNDCY+R +S G+PT +
Sbjct: 1035 FHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1083



 Score = 31.6 bits (70), Expect = 5.4
 Identities = 58/271 (21%), Positives = 102/271 (37%), Gaps = 39/271 (14%)

Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1070
            E    ++ + +EE   +      +EQ +    Q R+ + + +  +  ++ RR   S D+ 
Sbjct: 324  ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 383

Query: 1071 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1129
            K EE        +R K       +D ++ +  + K   +I      + R   E   +  +
Sbjct: 384  KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 435

Query: 1130 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1188
            + E + ILQ+  +R  +           +    E + +P I+ R  S + NL S      
Sbjct: 436  QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 478

Query: 1189 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1246
                +LN P        ++  S PPP+  +T      R     +S+   S    KT T  
Sbjct: 479  ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 531

Query: 1247 VATTQSPTPRSHSPSASQSGSQLRNRSVSGK 1277
                 +P P S  P  SQ    L+   V GK
Sbjct: 532  AVPMLTPKPYS-QPKNSQ--DVLKTFKVDGK 559


>gi|163310747 LIM and calponin homology domains 1 isoform d [Homo
            sapiens]
          Length = 902

 Score =  290 bits (743), Expect = 5e-78
 Identities = 249/852 (29%), Positives = 404/852 (47%), Gaps = 143/852 (16%)

Query: 206  KALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRHHKREDSFESLDSLGSRSLTSCSSDI 265
            K  +D    KRS RDSGY D W  ER + L+PPRH  R+DSF+SLDS GSRS  + S D+
Sbjct: 8    KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHG-RDDSFDSLDSFGSRSRQTPSPDV 66

Query: 266  TLRGGREGFESDTDSEFTF-KMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYV 324
             LRG  +G  SD++S+    K+ D  KDDMS RR S  EPK+A+PFN++LPNKS Q +YV
Sbjct: 67   VLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYV 126

Query: 325  PAPLRKKKPDKHEDNRRSWA---SPVYTEADGTFSRLFQKIYGENGSKSMSDVSAED--- 378
            PAPLRKKK ++ E+ R+SW+   SP+  E    +      +  +  S SM D+  E+   
Sbjct: 127  PAPLRKKKAER-EEYRKSWSTATSPLGGERPFRYGPR-TPVSDDAESTSMFDMRCEEEAA 184

Query: 379  VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEK---- 434
            VQ   + R E++Q I +QL+E+D KWQDDLA+WK RR+S + DL KK+EER+++EK    
Sbjct: 185  VQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAG 244

Query: 435  -QALEKSKRSSKTFKEMLQDRESQNQK--STVPSRRRMYSFDDVLEEGKRPPTMTVSEAS 491
                 + ++S KT++E++Q++E + ++      + R     + +L++       T+SEA 
Sbjct: 245  EDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ--YIERFTISEAV 302

Query: 492  YQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRST 551
               ER+E       S   + + ++F    + +     L  QS    +  A++ +  +R++
Sbjct: 303  L--ERLEMPKILERSHSTEPNLSSFLNDPNPMK---YLRQQSLPPPKFTATVETTIARAS 357

Query: 552  QMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVED 611
             ++++  + S   S  KT T +   ++TP+P+ SQ +    + +++ +D     NG    
Sbjct: 358  VLDTSMSAGS--GSPSKTVTPKAVPMLTPKPY-SQPKNSQDVLKTFKVDGKVSVNG---- 410

Query: 612  IKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSK 671
                                         E    EE+  R     +P  SL++ Q     
Sbjct: 411  -----------------------------ETVHREEEKERECPTVAPAHSLTKSQMFEGV 441

Query: 672  ATLSSTSGLDLMSESGEGEI------SPQREVSRSQDQFSDMRISINQTPGKSLDFGFTI 725
            A +   S L+L  ++G  EI      S  +E++ + ++            GKS      +
Sbjct: 442  ARVHG-SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIEL 500

Query: 726  KWDIPGIFVASVEAGSP-AEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLV 784
                P  F  +V   SP   F +     +   + N      D K+ E  M+   E   LV
Sbjct: 501  ASSEPQHFTTTVTRCSPTVAFVEFPSSPQ---LKNDVSEEKDQKKPENEMSGKVE---LV 554

Query: 785  MDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESN 844
            +  ++  K  SPE +                 ++T  F + +  +N              
Sbjct: 555  LS-QKVVKPKSPEPE----------------ATLTFPFLDKMPEAN-------------- 583

Query: 845  AFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQ 904
                     + L NL   SQ     S  S       P ++    W WD EEER+RQE+WQ
Sbjct: 584  --------QLHLPNL--NSQVDSPSSEKS-------PVMTPFKFWAWDPEEERRRQEKWQ 626

Query: 905  KEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLAT 964
            +EQ+RLLQE+YQ+EQ+KL+EEW++A++E E E  +Y +EE  ++    +  T        
Sbjct: 627  QEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTV------- 679

Query: 965  WEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQ 1024
                    S S+D+  T +   E      ++   D G   QD+   +++R+W++  Q + 
Sbjct: 680  -------SSSSADQLSTSSSMTEGSGTMNKI---DLG-NCQDE---KQDRRWKKSFQGDD 725

Query: 1025 EQKRLQAEAEEQ 1036
                L+    ++
Sbjct: 726  SDLLLKTRESDR 737



 Score =  113 bits (282), Expect = 1e-24
 Identities = 101/343 (29%), Positives = 160/343 (46%), Gaps = 60/343 (17%)

Query: 1011 ERERKWEQQLQEEQE---QKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSY 1067
            E ER+ +++ Q+EQE   Q+R Q E ++ K   E +K Q E+E E      + R+ ++  
Sbjct: 616  EEERRRQEKWQQEQERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDT 673

Query: 1068 DIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPS 1127
             +P T  +SS     D+  + S+       T  +G    +D +GN               
Sbjct: 674  VVPFTVSSSS----ADQLSTSSS------MTEGSGTMNKID-LGNC-------------- 708

Query: 1128 GAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNS 1187
                  Q   Q+ R +     D+S +  ++   ++  +   G +  G +L +  +P S  
Sbjct: 709  ------QDEKQDRRWKKSFQGDDSDLLLKTRESDR--LEEKGSLTEG-ALAHSGNPVSKG 759

Query: 1188 WRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGV 1247
              +   L+   G     +    ++ P Q   TSN           P  S+  VK  T  +
Sbjct: 760  VHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN-----------PTHSSEDVKPKT--L 806

Query: 1248 ATTQSPTPRSHSPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCF 1307
               +S   +  SPS        R +S+SGK++CS C   LGKGAAMIIE+L L +H+ CF
Sbjct: 807  PLDKSINHQIESPSE-------RRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCF 859

Query: 1308 KCVACECDLGGSSSGAEVRIRNHQLYCNDCYLRFKS-GRPTAM 1349
            +C  C+  LG + SG +VRIRN  L CNDCY+R +S G+PT +
Sbjct: 860  RCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 902



 Score = 31.6 bits (70), Expect = 5.4
 Identities = 58/271 (21%), Positives = 102/271 (37%), Gaps = 39/271 (14%)

Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1070
            E    ++ + +EE   +      +EQ +    Q R+ + + +  +  ++ RR   S D+ 
Sbjct: 170  ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 229

Query: 1071 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1129
            K EE        +R K       +D ++ +  + K   +I      + R   E   +  +
Sbjct: 230  KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 281

Query: 1130 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1188
            + E + ILQ+  +R  +           +    E + +P I+ R  S + NL S      
Sbjct: 282  QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 324

Query: 1189 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1246
                +LN P        ++  S PPP+  +T      R     +S+   S    KT T  
Sbjct: 325  ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 377

Query: 1247 VATTQSPTPRSHSPSASQSGSQLRNRSVSGK 1277
                 +P P S  P  SQ    L+   V GK
Sbjct: 378  AVPMLTPKPYS-QPKNSQ--DVLKTFKVDGK 405


>gi|163310749 LIM and calponin homology domains 1 isoform e [Homo
            sapiens]
          Length = 890

 Score =  289 bits (740), Expect = 1e-77
 Identities = 251/852 (29%), Positives = 404/852 (47%), Gaps = 155/852 (18%)

Query: 206  KALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRHHKREDSFESLDSLGSRSLTSCSSDI 265
            K  +D    KRS RDSGY D W  ER + L+PPRH  R+DSF+SLDS GSRS  + S D+
Sbjct: 8    KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHG-RDDSFDSLDSFGSRSRQTPSPDV 66

Query: 266  TLRGGREGFESDTDSEFTF-KMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYV 324
             LRG  +G  SD++S+    K+ D  KDDMS RR S  EPK+A+PFN++LPNKS Q +YV
Sbjct: 67   VLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYV 126

Query: 325  PAPLRKKKPDKHEDNRRSWA---SPVYTEADGTFSRLFQKIYGENGSKSMSDVSAED--- 378
            PAPLRKKK ++ E+ R+SW+   SP+  E      R F+       S SM D+  E+   
Sbjct: 127  PAPLRKKKAER-EEYRKSWSTATSPLGGE------RPFR-------STSMFDMRCEEEAA 172

Query: 379  VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEK---- 434
            VQ   + R E++Q I +QL+E+D KWQDDLA+WK RR+S + DL KK+EER+++EK    
Sbjct: 173  VQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAG 232

Query: 435  -QALEKSKRSSKTFKEMLQDRESQNQK--STVPSRRRMYSFDDVLEEGKRPPTMTVSEAS 491
                 + ++S KT++E++Q++E + ++      + R     + +L++       T+SEA 
Sbjct: 233  EDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ--YIERFTISEAV 290

Query: 492  YQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRST 551
               ER+E       S   + + ++F    + +     L  QS    +  A++ +  +R++
Sbjct: 291  L--ERLEMPKILERSHSTEPNLSSFLNDPNPMK---YLRQQSLPPPKFTATVETTIARAS 345

Query: 552  QMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVED 611
             ++++  + S   S  KT T +   ++TP+P+ SQ +    + +++ +D     NG    
Sbjct: 346  VLDTSMSAGS--GSPSKTVTPKAVPMLTPKPY-SQPKNSQDVLKTFKVDGKVSVNG---- 398

Query: 612  IKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSK 671
                                         E    EE+  R     +P  SL++ Q     
Sbjct: 399  -----------------------------ETVHREEEKERECPTVAPAHSLTKSQMFEGV 429

Query: 672  ATLSSTSGLDLMSESGEGEI------SPQREVSRSQDQFSDMRISINQTPGKSLDFGFTI 725
            A +   S L+L  ++G  EI      S  +E++ + ++            GKS      +
Sbjct: 430  ARVHG-SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIEL 488

Query: 726  KWDIPGIFVASVEAGSP-AEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLV 784
                P  F  +V   SP   F +     +   + N      D K+ E  M+   E   LV
Sbjct: 489  ASSEPQHFTTTVTRCSPTVAFVEFPSSPQ---LKNDVSEEKDQKKPENEMSGKVE---LV 542

Query: 785  MDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESN 844
            +  ++  K  SPE +                 ++T  F + +  +N              
Sbjct: 543  LS-QKVVKPKSPEPE----------------ATLTFPFLDKMPEAN-------------- 571

Query: 845  AFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQ 904
                     + L NL   SQ     S  S       P ++    W WD EEER+RQE+WQ
Sbjct: 572  --------QLHLPNL--NSQVDSPSSEKS-------PVMTPFKFWAWDPEEERRRQEKWQ 614

Query: 905  KEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLAT 964
            +EQ+RLLQE+YQ+EQ+KL+EEW++A++E E E  +Y +EE  ++    +  T        
Sbjct: 615  QEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTV------- 667

Query: 965  WEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQ 1024
                    S S+D+  T +   E      ++   D G   QD+   +++R+W++  Q + 
Sbjct: 668  -------SSSSADQLSTSSSMTEGSGTMNKI---DLG-NCQDE---KQDRRWKKSFQGDD 713

Query: 1025 EQKRLQAEAEEQ 1036
                L+    ++
Sbjct: 714  SDLLLKTRESDR 725



 Score =  113 bits (282), Expect = 1e-24
 Identities = 99/339 (29%), Positives = 157/339 (46%), Gaps = 58/339 (17%)

Query: 1012 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPK 1071
            R+ KW+Q+ QE   Q+R Q E ++ K   E +K Q E+E E      + R+ ++   +P 
Sbjct: 609  RQEKWQQE-QERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDTVVPF 665

Query: 1072 TEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAEL 1131
            T  +SS     D+  + S+       T  +G    +D +GN    +              
Sbjct: 666  TVSSSSA----DQLSTSSSM------TEGSGTMNKID-LGNCQDEK-------------- 700

Query: 1132 ERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQP 1191
                  Q+ R +     D+S +  ++   ++  +   G +  G +L +  +P S    + 
Sbjct: 701  ------QDRRWKKSFQGDDSDLLLKTRESDR--LEEKGSLTEG-ALAHSGNPVSKGVHED 751

Query: 1192 PWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQ 1251
              L+   G     +    ++ P Q   TSN           P  S+  VK  T  +   +
Sbjct: 752  HQLDTEAGAPHCGTNPQLAQDPSQNQQTSN-----------PTHSSEDVKPKT--LPLDK 798

Query: 1252 SPTPRSHSPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCFKCVA 1311
            S   +  SPS        R +S+SGK++CS C   LGKGAAMIIE+L L +H+ CF+C  
Sbjct: 799  SINHQIESPSE-------RRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGI 851

Query: 1312 CECDLGGSSSGAEVRIRNHQLYCNDCYLRFKS-GRPTAM 1349
            C+  LG + SG +VRIRN  L CNDCY+R +S G+PT +
Sbjct: 852  CKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 890


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 80.5 bits (197), Expect = 1e-14
 Identities = 70/294 (23%), Positives = 136/294 (46%), Gaps = 17/294 (5%)

Query: 893  QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNS 952
            +E++ +R+++ ++EQ    +++ +REQ+  RE+  R +Q+  RE  +   E+        
Sbjct: 385  REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE 444

Query: 953  MSLTTREPSLATW----EATWSEGSKSSDREGTRAGEEERRQ---PQEEVVHEDQGKKPQ 1005
              L   +     W    E T     +   ++  R  EEERR+     EE    +Q ++ +
Sbjct: 445  QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE 504

Query: 1006 DQLVIERERKWEQQLQEEQEQKRLQ--AEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP 1063
             QL  E+E + EQ+L+ ++E++RLQ    +E+Q R  +E++R+  ++RE   R+ Q RR 
Sbjct: 505  QQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR- 563

Query: 1064 VDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKE 1123
             +     + EE     L   R + R    L      +       +++  +   +RR ++ 
Sbjct: 564  -EQRLKREQEERRDQLL--KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620

Query: 1124 QVPSGAELERQQIL----QEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRR 1173
            +     E  RQQ+L    QE R++  L  +    R++     +E   L   ++R
Sbjct: 621  KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKR 674



 Score = 70.5 bits (171), Expect = 1e-11
 Identities = 53/172 (30%), Positives = 88/172 (51%), Gaps = 10/172 (5%)

Query: 896  ERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSL 955
            E K+Q+R ++ QDR+ QE+ ++E  K RE   R ++E  +E       EL         L
Sbjct: 224  EEKQQQR-RERQDRVFQEEEEKEWRK-RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL 281

Query: 956  TTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEE-----VVHEDQGKKPQDQLVI 1010
              +E      E    +     +++  R  EEERR+ QEE        E Q ++ + QL  
Sbjct: 282  ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341

Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRR 1062
            E+E + EQQL+ EQE++R +   ++ +R  EE++R+ ++ RE  +R  Q  R
Sbjct: 342  EQEERREQQLRREQEEERRE---QQLRREQEEERREQQLRREQQLRREQQLR 390



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 66/255 (25%), Positives = 121/255 (47%), Gaps = 42/255 (16%)

Query: 893  QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNS 952
            Q EER+++ R ++E+    +E+ Q+E+E+L  E +  ++  ERE     D++   L    
Sbjct: 914  QREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK---LQQKE 970

Query: 953  MSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIER 1012
              L   EP          E  +  +RE     EEE +Q +E+++ E++ K+        R
Sbjct: 971  EQLLGEEP----------EKRRRQEREKKYREEEELQQEEEQLLREEREKR--------R 1012

Query: 1013 ERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKT 1072
             ++WE+Q +++ E   LQ E E+  R   E++R  E ER       QYR   +  ++ + 
Sbjct: 1013 RQEWERQYRKKDE---LQQEEEQLLREEREKRRLQERER-------QYR---EEEELQQE 1059

Query: 1073 EEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRR--SKKEQVPSGAE 1130
            EE     L G+  ++R   EL+     +    +  +Q+      +RR   ++ Q     E
Sbjct: 1060 EEQ----LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEE 1115

Query: 1131 L--ERQQILQEMRKR 1143
            L  E +Q+L+E R++
Sbjct: 1116 LQQEEEQLLREEREK 1130



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 66/275 (24%), Positives = 126/275 (45%), Gaps = 24/275 (8%)

Query: 893  QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEA-----ERENSKYLDEELMV 947
            QEEE + Q+R + EQ    +++ +REQ   REE +R +QE      +RE  +  D+ L  
Sbjct: 522  QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR 581

Query: 948  LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEE-----VVHEDQGK 1002
                      RE      +    E  +  ++E  R    +R +P+EE     +  E+Q +
Sbjct: 582  EEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641

Query: 1003 KPQDQLVIERERKWEQQLQEEQEQKRLQ----AEAEEQKRP---AEEQKRQAEIERETSV 1055
            + Q QL  E++ + EQ+L+ E+E++RL+     E EE++R    AEE++ QA    ++ +
Sbjct: 642  RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701

Query: 1056 RIYQYR-------RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLD 1108
              +Q++       R    Y  P+ +E        +  + R  +EL      +    +  +
Sbjct: 702  PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761

Query: 1109 QIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKR 1143
            +     + Q +++++       L  +  L+E R+R
Sbjct: 762  EQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER 796



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 68/262 (25%), Positives = 127/262 (48%), Gaps = 34/262 (12%)

Query: 892  DQEEERKRQERWQKEQDRLLQEKYQREQEKL---------REEWQRAKQEAERENSKYLD 942
            ++ E+R+RQER +K ++   +E+ Q+E+E+L         R+EW+R  Q  +++  +  +
Sbjct: 976  EEPEKRRRQEREKKYRE---EEELQQEEEQLLREEREKRRRQEWER--QYRKKDELQQEE 1030

Query: 943  EELMVLSSNSMSLTTREPSLATWEATWSEGSK--SSDREGTRAGEEERRQPQEEVVHEDQ 1000
            E+L+        L  RE      E    E  +    +RE  R  E ER+  +EE + +++
Sbjct: 1031 EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE 1090

Query: 1001 GKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQY 1060
             +  +++    R ++ E+Q +EE+E   LQ E E+  R   E++R+ E+ER       QY
Sbjct: 1091 EQLLREEPEKRRRQERERQCREEEE---LQQEEEQLLREEREKRRRQELER-------QY 1140

Query: 1061 RRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRS 1120
            R   +  ++ + EE     L  +  + R   EL+     +    +  +Q+      +RR 
Sbjct: 1141 R---EEEEVQQEEEQ----LLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ 1193

Query: 1121 KKE-QVPSGAELERQQILQEMR 1141
            ++E Q     EL+RQ+  Q  R
Sbjct: 1194 ERERQYREEEELQRQKRKQRYR 1215



 Score = 68.6 bits (166), Expect = 4e-11
 Identities = 63/277 (22%), Positives = 119/277 (42%), Gaps = 26/277 (9%)

Query: 892  DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 951
            +QE E    E   ++Q+RL Q   QR  E+L   W++ ++  ERE  +  +E+L     +
Sbjct: 143  EQERELAEGEEQSEKQERLEQRDRQRRDEEL---WRQRQEWQEREERRAEEEQLQSCKGH 199

Query: 952  SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK--------- 1002
                   E  L   E           R+G    +++RR+ Q+ V  E++ K         
Sbjct: 200  ETEEFPDEEQLRRRELL------ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVL 253

Query: 1003 KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRR 1062
            + +++ + E E + +++LQEE+EQ R     E ++   EE+++Q  + RE      Q RR
Sbjct: 254  RKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE-----QQLRR 308

Query: 1063 PVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKK 1122
              +     + EE        ++ + R   +L      +       +Q       Q R ++
Sbjct: 309  KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368

Query: 1123 EQVPSGAELERQQIL---QEMRKRTPLHNDNSWIRQR 1156
            E+     +L R+Q L   Q++R+   L  +    R++
Sbjct: 369  EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405



 Score = 68.2 bits (165), Expect = 5e-11
 Identities = 76/280 (27%), Positives = 118/280 (42%), Gaps = 42/280 (15%)

Query: 889  WVWDQEE--ERKRQE-------RWQKEQDRLLQEKYQREQEKLREEW---QRAKQEAERE 936
            W W  EE  ER RQ        R Q+E+    +E+ QREQ  L EE    QR +Q  ERE
Sbjct: 769  WQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRERE 828

Query: 937  NS-KYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEV 995
               ++L+EE          L  RE +    E    E     D+E  R+ E+ R Q     
Sbjct: 829  KELQFLEEE--------EQLQRRERAQQLQE---EEDGLQEDQERRRSQEQRRDQKWRWQ 877

Query: 996  VHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSV 1055
            + E++ ++      +  +   ++QL++EQ+   LQ E EE +R   E++R+ E ER    
Sbjct: 878  LEEERKRRRH---TLYAKPALQEQLRKEQQL--LQEEEEELQREEREKRRRQEQER---- 928

Query: 1056 RIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTS 1115
               QYR         + ++     L  +R K R       Y  +K    K    +G    
Sbjct: 929  ---QYREE------EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPE 979

Query: 1116 SQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQ 1155
             +RR ++E+     E  +Q+  Q +R+         W RQ
Sbjct: 980  KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019



 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 64/278 (23%), Positives = 120/278 (43%), Gaps = 24/278 (8%)

Query: 890  VWDQEEE---RKRQERWQKEQDRLLQEKYQREQEKLREEWQRAK---QEAERENSKYLDE 943
            V+ +EEE   RKR+   +KE+++L +E+ QR++E   EE Q  K   QE  RE  +   +
Sbjct: 237  VFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ 296

Query: 944  ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGE-----EERRQPQEEVVHE 998
            +  +     +     E      E    +  +   +E  R  +     EERR+ Q     E
Sbjct: 297  QQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE 356

Query: 999  DQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIY 1058
            ++ ++ Q +   E ER+ +Q  +E+Q ++  Q   E+Q R  ++ +R+ ++ RE  +R  
Sbjct: 357  EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 416

Query: 1059 QYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELD--------DYSTNKNGNNKYLDQI 1110
            Q  R        + EE        +R + R   E +        +  T ++   +   Q+
Sbjct: 417  QQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476

Query: 1111 GNMTSSQRRSK-----KEQVPSGAELERQQILQEMRKR 1143
                  +RR +     +E+     E   QQ+ +E  +R
Sbjct: 477  KRDQEEERRERWLKLEEEERREQQERREQQLRREQEER 514



 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 70/286 (24%), Positives = 127/286 (44%), Gaps = 42/286 (14%)

Query: 894  EEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSM 953
            E + +++E  Q+E+++LL+E+ ++ + + RE   R ++E ++E  + L EE        +
Sbjct: 1077 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQEL 1136

Query: 954  SLTTREPSLATWEATW-----SEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQL 1008
                RE      E         E  +  + E     EEE +Q +E+++ E+Q K+ Q   
Sbjct: 1137 ERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ--- 1193

Query: 1009 VIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVR---IY------- 1058
              ERER++ ++ +E Q QKR Q   +E +R   + K Q E E+E +VR   +Y       
Sbjct: 1194 --ERERQYREE-EELQRQKRKQRYRDEDQR--SDLKWQWEPEKENAVRDNKVYCKGRENE 1248

Query: 1059 QYRRPVDSYDIPKTEEASSGFLPG-----DRNKSR-------------STTELDDYSTNK 1100
            Q+R+  DS    +  +     L G     DR + R                E ++    K
Sbjct: 1249 QFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAK 1308

Query: 1101 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPL 1146
              + K  ++   +   +   ++ Q       E +Q+LQE R+  PL
Sbjct: 1309 RRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQE-REEQPL 1353



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 50/189 (26%), Positives = 96/189 (50%), Gaps = 26/189 (13%)

Query: 893  QEEERKRQER-WQKEQDRLLQEK---YQREQEKLREEWQRAKQEAERENSKYLDEELMVL 948
            Q++ R+RQ+R +Q+E+++  +++    ++E+EKL+EE  + ++E + E     +E+L  L
Sbjct: 227  QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE-----EEQLRKL 281

Query: 949  SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQL 1008
                +    +E           +  +    E  R  +EERR+ QE    E Q ++ + QL
Sbjct: 282  ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER--REQQEERREQQL 339

Query: 1009 VIERERKWEQQLQ--------------EEQEQKR-LQAEAEEQKRPAEEQKRQAEIERET 1053
              E+E + EQQL+              E++E++R  Q   E+Q R  ++ +R+ ++ RE 
Sbjct: 340  RREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399

Query: 1054 SVRIYQYRR 1062
             +R  Q  R
Sbjct: 400  QLRREQQLR 408



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 59/262 (22%), Positives = 125/262 (47%), Gaps = 22/262 (8%)

Query: 892  DQEEERKRQERWQK---EQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVL 948
            ++E + +RQER Q+   ++DR  +E+ Q  QE   EE Q  +QE +R+  +  +E+ +  
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG--EEQQLRRQERDRKFRE--EEQQLRR 1702

Query: 949  SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQL 1008
                      E  L   E       +   R+ T   +  R++   +++ E+Q +  +++ 
Sbjct: 1703 QERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQ 1762

Query: 1009 VI---ERERKW--EQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE--TSVRIYQYR 1061
             +   ER+RK+  E+QL++E+E+++L+++  ++K   EEQ RQ   E++     R  +YR
Sbjct: 1763 QLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYR 1822

Query: 1062 RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSK 1121
               +   + + E+         + + R     + ++T +    +   ++      +RR +
Sbjct: 1823 WEEEQLQLEEQEQRLR------QERDRQYRAEEQFATQEKSRREE-QELWQEEEQKRRQE 1875

Query: 1122 KEQVPSGAELERQQILQEMRKR 1143
            +E+      + RQQ  +E R R
Sbjct: 1876 RERKLREEHIRRQQ-KEEQRHR 1896



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 55/264 (20%), Positives = 120/264 (45%), Gaps = 19/264 (7%)

Query: 892  DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 951
            ++E++  RQER +K ++   +E+  R QE+ R+  +  +Q  +  + K+ +EE ++    
Sbjct: 1418 EEEQQLSRQERDRKFRE---EEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE 1474

Query: 952  SMSLTTREPSLATWEATWSEGSKSSDR----EGTRAGEEERR-QPQEEVVHEDQGKKP-- 1004
               L  +E      E       +  DR    +  R+ E ER+   +E+ +H  Q ++   
Sbjct: 1475 EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFL 1534

Query: 1005 QDQLVIERERKWEQQLQEE----QEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQY 1060
            Q++  + R+ + +Q+ Q+     +E+++L+ E EEQ+   +E+ R+  +E +   R  Q 
Sbjct: 1535 QEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594

Query: 1061 RRPVDSYDIPKTEEASSGFLPGDRNKSRSTTEL-----DDYSTNKNGNNKYLDQIGNMTS 1115
            R+ ++     + +E           K R   +L     +     +  + K+L++   +  
Sbjct: 1595 RKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRR 1654

Query: 1116 SQRRSKKEQVPSGAELERQQILQE 1139
             +R  +          E +Q+LQE
Sbjct: 1655 QEREQQLRHDRDRKFREEEQLLQE 1678



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 65/266 (24%), Positives = 119/266 (44%), Gaps = 29/266 (10%)

Query: 889  WVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVL 948
            W+  +EE  + ++  +K+Q +  QE+ +RE+    EE +R +Q+  RE     ++E    
Sbjct: 457  WLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE---- 512

Query: 949  SSNSMSLTTREPSLATWEATWSEGSKSSDREGTR----AGEEERRQPQEEVVHEDQGKKP 1004
                  L  +E      +   SE     ++E  R      EEE+R  QE    E + K+ 
Sbjct: 513  ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER--REQRLKRE 570

Query: 1005 Q----DQLVIERERKWEQQLQEEQEQKRLQ-AEAEEQKRPAEEQKRQAEIERETSVRIYQ 1059
            Q    DQL+   E + +Q+L+ EQE++  Q  + EE +R  +E++R+  ++RE      +
Sbjct: 571  QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEP---EE 627

Query: 1060 YRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRR 1119
             RR      + K+EE         +   R   E  +    +    + L+Q       + R
Sbjct: 628  ERR----QQLLKSEEQEE---RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER 680

Query: 1120 SKKEQVPSGAELERQQILQEMRKRTP 1145
             ++E     AE E++Q  + ++ R P
Sbjct: 681  REQEL----AEEEQEQARERIKSRIP 702



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 59/286 (20%), Positives = 129/286 (45%), Gaps = 33/286 (11%)

Query: 891  WDQEE----ERKRQERWQKEQDRLLQEKYQREQEKLREEWQ--RAKQEAERENSKYLDEE 944
            W Q +    E ++ ER ++++ +    K Q E++ LREE +  R +QE +R   K+ +EE
Sbjct: 1286 WQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR---KFREEE 1342

Query: 945  LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEE----VVHEDQ 1000
             ++       L  +E      +  + E       +G +  EEE+R  ++E     + E+Q
Sbjct: 1343 QLLQEREEQPLRRQER-----DRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQ 1397

Query: 1001 GKKPQD---QLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRI 1057
              + Q+   QL  +R+RK+ ++ Q+   Q+R +   EE+++   +++ +  +E E  +R 
Sbjct: 1398 QLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQ 1457

Query: 1058 YQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQ 1117
             ++R+  +   + +  E         + + R   E +     +  + K+ +Q       +
Sbjct: 1458 ERHRKFREEEQLLQEREEQQ---LHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPE 1514

Query: 1118 RRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1163
            R+  +E+         QQ+ ++ R+R  L  +    RQ      ++
Sbjct: 1515 RKFLEEE---------QQLHRQQRQRKFLQEEQQLRRQERGQQRRQ 1551



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 60/271 (22%), Positives = 122/271 (45%), Gaps = 37/271 (13%)

Query: 886  PSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEEL 945
            P R   ++E++  RQ+R         Q K+ +E+++LR + +R +Q  +  + K+ +EE 
Sbjct: 1513 PERKFLEEEQQLHRQQR---------QRKFLQEEQQLRRQ-ERGQQRRQDRDRKFREEEQ 1562

Query: 946  MVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ----G 1001
            +        L+ +E                 DR+     ++ RRQ QE    ED+     
Sbjct: 1563 LRQEREEQQLSRQE----------------RDRKFRLEEQKVRRQEQERKFMEDEQQLRR 1606

Query: 1002 KKPQDQLVIERERKW--EQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQ 1059
            ++ Q QL  ER+RK+  ++QL +E+E+++L  + E  ++  EE+ +    ERE  +R  +
Sbjct: 1607 QEGQQQLRQERDRKFREDEQLLQEREEQQLHRQ-ERDRKFLEEEPQLRRQEREQQLRHDR 1665

Query: 1060 YRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQ-R 1118
             R+  +   + +  E         + + R   E +     +    K+L +   +   +  
Sbjct: 1666 DRKFREEEQLLQEGEEQQ---LRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELE 1722

Query: 1119 RSKKEQVPSGAELERQQILQEMRKRTPLHND 1149
            R  +E+     E E++Q+ ++ R R  L  +
Sbjct: 1723 RKFREEEQLRQETEQEQLRRQERYRKILEEE 1753



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 62/280 (22%), Positives = 115/280 (41%), Gaps = 43/280 (15%)

Query: 892  DQEEERKRQERWQKEQDRLLQEKY-------------------QREQEKLREEWQRAKQE 932
            D+E  R+RQE WQ+ ++R  +E+                    +RE  +LR + +  KQ+
Sbjct: 170  DEELWRQRQE-WQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQ 228

Query: 933  AERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQ 992
              RE    + +E             RE  L   E    E      RE     E+ R+  +
Sbjct: 229  QRRERQDRVFQE-----EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283

Query: 993  EEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052
            +E+  E Q ++ Q Q +   ++   +Q +E +EQ       +E++R  +E++ Q E  RE
Sbjct: 284  QELRRERQEEEQQQQRLRREQQLRRKQEEERREQ-------QEERREQQERREQQEERRE 336

Query: 1053 TSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGN 1112
              +R  Q  R        + EE     L  ++ + R   +L           + L +   
Sbjct: 337  QQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQL--------RREQQLRREQQ 388

Query: 1113 MTSSQRRSKKEQVPSGAELERQQIL---QEMRKRTPLHND 1149
            +   Q+  +++Q+    +L R+Q L   Q++R+   L  +
Sbjct: 389  LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 60/300 (20%), Positives = 124/300 (41%), Gaps = 48/300 (16%)

Query: 892  DQEEERKRQERWQKEQDRLLQEKYQREQEKLRE-------EWQRAKQEAERENSKYLDEE 944
            + EEER++Q    +EQ+   Q++ +REQ++ RE       E +R +Q  +RE+ +   E+
Sbjct: 624  EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683

Query: 945  LMVLSSNSMSLTTREPSLATWE------------ATWSEGSKSSDREGTRAGEEERRQPQ 992
             +       +    +  +  W+              +S   K   +   +  EE+RR+ +
Sbjct: 684  ELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRE 743

Query: 993  EEV--VHEDQGKKPQDQLVIERERKWEQQLQE----------------EQEQKRLQAEAE 1034
             E+    E++  + Q +    R+  W+ Q +E                EQ +++L+AE  
Sbjct: 744  SELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER 803

Query: 1035 EQKR----PAE---EQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKS 1087
            +Q+     P E   EQ+R+   ERE  ++  +    +   +  +  +     L  D+ + 
Sbjct: 804  QQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERR 863

Query: 1088 RSTTELDD----YSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKR 1143
            RS  +  D    +   +    +           ++  K++Q+    E E Q+  +E R+R
Sbjct: 864  RSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRR 923



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 68/290 (23%), Positives = 131/290 (45%), Gaps = 33/290 (11%)

Query: 890  VWDQEEERKRQE---RWQKEQDRLLQEK---YQREQEKLREEWQRAKQEAERENSKYLDE 943
            V  +EE+  R+E   R ++E +R  +E+    Q E++ LREE ++ +QE ER+  +  +E
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE--EE 1203

Query: 944  ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG---TRAGEEER-RQPQEEVVHED 999
            EL             + S   W+  W    +++ R+     +  E E+ RQ ++  + + 
Sbjct: 1204 ELQRQKRKQRYRDEDQRSDLKWQ--WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDR 1261

Query: 1000 QGKKPQDQLVIERE--------RKWEQQ----LQEEQEQKRLQAEAEEQKRPAEEQKRQA 1047
            Q ++    L+ E++        R+W+Q+     +EEQ ++  Q EA+ + R ++E+K+  
Sbjct: 1262 QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLL 1321

Query: 1048 EIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYL 1107
              ERE   R  +  R     +    E         +R++     EL     ++    K+L
Sbjct: 1322 REEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEEL----RHQEQGRKFL 1377

Query: 1108 DQIGNMTSSQRRSK--KEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQ 1155
            ++   +   +R  K  KE+     + ER+Q L++ R R     +    RQ
Sbjct: 1378 EEEQRLRRQERERKFLKEEQQLRCQ-EREQQLRQDRDRKFREEEQQLSRQ 1426



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 63/292 (21%), Positives = 121/292 (41%), Gaps = 32/292 (10%)

Query: 892  DQEEERKRQERWQKEQDRLLQEK----YQREQEK--LREEWQRAKQEAERENSKYLD--E 943
            +QE+ R+ +ER  +E++ L ++K    Y+ E ++  L+ +W+  K+ A R+N  Y    E
Sbjct: 1187 EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246

Query: 944  ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003
                       L  R+           +  +  ++E  R  + +R  P+EE +  ++ K+
Sbjct: 1247 NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306

Query: 1004 PQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEE------QKRQAEIERETSVRI 1057
             +      R+RK        QE+K+L  E  E+KR  +E      ++ Q   ERE     
Sbjct: 1307 AK-----RRDRK-------SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR 1354

Query: 1058 YQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQ 1117
             Q R      +  + +E    FL  ++   R   E       +    +  +Q       +
Sbjct: 1355 RQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR 1414

Query: 1118 RRSKKEQVPSGAELER------QQILQEMRKRTPLHNDNSWIRQRSASVNKE 1163
            +  ++EQ  S  E +R      QQ+ ++ R+R  L  +    ++R     +E
Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE 1466



 Score = 53.9 bits (128), Expect = 1e-06
 Identities = 36/159 (22%), Positives = 77/159 (48%), Gaps = 5/159 (3%)

Query: 894  EEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSM 953
            EEE+ R ER +++  R  +++  RE+E+LR+E +  +  ++  + K+ +EE +       
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ 1810

Query: 954  SLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERE 1013
             L    P     +  W E     + +  R  +E  RQ + E     Q K  +++  + +E
Sbjct: 1811 QL---RPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQE 1867

Query: 1014 RKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052
               EQ+ ++E+E+K  +     Q++  +  ++  EI+ +
Sbjct: 1868 E--EQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904



 Score = 52.0 bits (123), Expect = 4e-06
 Identities = 42/171 (24%), Positives = 88/171 (51%), Gaps = 16/171 (9%)

Query: 893  QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERE-----NSKYLDEELMV 947
            +E+E+  QER +++  R      +R+++ L EE Q  +QE E++     + K+ +EE ++
Sbjct: 1622 REDEQLLQEREEQQLHR-----QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLL 1676

Query: 948  LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE-EVVHEDQGKKPQD 1006
                   L  +E      E       +  +R+  +  ++ RRQ  E +   E+Q ++  +
Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736

Query: 1007 QLVIERERKW-----EQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052
            Q  + R+ ++     E+QL+ E+E+++L+ +  ++K   EEQ RQ   E++
Sbjct: 1737 QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 62/313 (19%), Positives = 116/313 (37%), Gaps = 40/313 (12%)

Query: 268  RGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAP 327
            R  R+  E +   +FT++ Q   K +   +R+SA  P       +    + +Q      P
Sbjct: 753  RAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLP 812

Query: 328  LRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRY 387
              ++K  +    R       + E +    R  +               A+ +Q       
Sbjct: 813  EEEEKEQRRRQRREREKELQFLEEEEQLQRRER---------------AQQLQEEEDGLQ 857

Query: 388  EEMQKIKSQLKEQDQKWQDDLAKWKDRRK-----------SYTSDLQKKKEEREEIEKQA 436
            E+ ++ +SQ + +DQKW+  L + + RR+               + Q  +EE EE++++ 
Sbjct: 858  EDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREE 917

Query: 437  LEKSKRSSK----TFKEMLQDRESQ-----NQKSTVPSRRRMYSFDDVLEEGKRPPTMTV 487
             EK +R  +      +E LQ  E Q      +K     R R Y  D  L++ +       
Sbjct: 918  REKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEE 977

Query: 488  SEASYQSERVEEKGATYPSEIPKEDSTTFAKRED---RVTTEIQLPSQSPVEEQSPASLS 544
             E   + ER  EK      E+ +E+     +  +   R   E Q   +  ++++    L 
Sbjct: 978  PEKRRRQER--EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLR 1035

Query: 545  SLRSRSTQMESTR 557
              R +    E  R
Sbjct: 1036 EEREKRRLQERER 1048



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 41/214 (19%), Positives = 92/214 (42%), Gaps = 6/214 (2%)

Query: 328 LRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDV---SAEDVQNLRQ 384
           LR+K  ++ +  RR     V+ E +    R  + +  +   K   +      E  +   Q
Sbjct: 218 LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQ 277

Query: 385 LRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 444
           LR  E Q+++ + +E++Q+ Q    + + RRK      ++++E RE+ E++  ++ +R  
Sbjct: 278 LRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQ 337

Query: 445 KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATY 504
           +  +E  + RE Q ++     RR      +  EE +        +   + +   E+    
Sbjct: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRR 397

Query: 505 PSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQ 538
             ++ +E      +RE ++  E QL  +  +  +
Sbjct: 398 EQQLRREQQ---LRREQQLRREQQLRREQQLRRE 428



 Score = 45.4 bits (106), Expect = 4e-04
 Identities = 39/191 (20%), Positives = 86/191 (45%), Gaps = 11/191 (5%)

Query: 847  ESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKE 906
            E +  +    + L+R+ ++ +    + + P+     +    R    +EEE+ RQER +++
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787

Query: 907  QDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWE 966
                  ++  RE+E+LR+E +  +   ++ + KY  EE        + L  +E  L    
Sbjct: 1788 LRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE------EQLQLEEQEQRLRQ-- 1839

Query: 967  ATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQ 1026
                   +    E     E+ RR+ QE    E+Q ++ + +  +  E    QQ +E++ +
Sbjct: 1840 ---ERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHR 1896

Query: 1027 KRLQAEAEEQK 1037
            +  + +++E K
Sbjct: 1897 QVGEIKSQEGK 1907



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 32/155 (20%), Positives = 71/155 (45%), Gaps = 15/155 (9%)

Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQA 436
           E+ +  ++L  EE ++ + ++K +  KWQ  L    D R+S      +K+E +   ++Q 
Sbjct: 677 EEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQE 736

Query: 437 LEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEE---------GKRPPTMTV 487
            ++ +R S+      Q+ E  +++     +RR +++    EE           RPP    
Sbjct: 737 EKRRRRESEL---QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQ 793

Query: 488 SEASYQSERVEEKGATYPSEIPKEDSTTFAKREDR 522
            E   ++E  +++   +   +P+E+     +R+ R
Sbjct: 794 RERQLRAEERQQREQRF---LPEEEEKEQRRRQRR 825



 Score = 40.4 bits (93), Expect = 0.012
 Identities = 52/250 (20%), Positives = 105/250 (42%), Gaps = 28/250 (11%)

Query: 334  DKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKI 393
            ++ E  RR      Y + D    +  +++ GE   K       +  +   +L+ EE Q +
Sbjct: 946  EEREKRRRQERERQYRK-DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004

Query: 394  KSQL-KEQDQKWQDDLAKWKDRRKSYTSDLQKKKEE--REEIEKQALEKSKRSSKTFKEM 450
            + +  K + Q+W+    K KD       +LQ+++E+  REE EK+ L++ +R  +  +E+
Sbjct: 1005 REEREKRRRQEWERQYRK-KD-------ELQQEEEQLLREEREKRRLQERERQYREEEEL 1056

Query: 451  LQDRESQNQKSTVPSRR----RMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPS 506
             Q+ E    +     RR    R Y  ++ L++ +        E   + ER  E+      
Sbjct: 1057 QQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER--ERQCREEE 1114

Query: 507  EIPKEDSTTFAKRED---RVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLP 563
            E+ +E+     +  +   R   E Q   +  V+++    L     +  + E       L 
Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE-------LE 1167

Query: 564  RSYRKTDTVR 573
            R YR+ + ++
Sbjct: 1168 RQYREEEELQ 1177



 Score = 37.7 bits (86), Expect = 0.075
 Identities = 39/202 (19%), Positives = 81/202 (40%), Gaps = 15/202 (7%)

Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKD---------RRKSYTSDLQKKKE 427
           E+ +  +QLR E+  + + QL+ + Q  ++   + +          R +    + Q ++E
Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428

Query: 428 EREEIEKQALEKSKRSSKTFKEMLQ-----DRESQNQKSTVPSRRRMYSFDDVLEEGKRP 482
           + EE  +Q  E+ +R  +  +E  +      RE + ++     R++    D   E  +R 
Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488

Query: 483 PTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPAS 542
             +   E   Q ER E++      E  +E      + E+R+   ++   Q   E++    
Sbjct: 489 LKLEEEERREQQERREQQ-LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547

Query: 543 LSSLRSRSTQMESTRVSASLPR 564
               R    ++E  R    L R
Sbjct: 548 QLLKREEEKRLEQERREQRLKR 569



 Score = 37.7 bits (86), Expect = 0.075
 Identities = 43/229 (18%), Positives = 98/229 (42%), Gaps = 40/229 (17%)

Query: 329 RKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYE 388
           R+++ ++HE  RR               +  ++   E   +    +  E+ +  ++ R +
Sbjct: 460 REEETERHEQERRK--------------QQLKRDQEEERRERWLKLEEEERREQQERREQ 505

Query: 389 EMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFK 448
           ++++ + + +EQ  K Q++  + + R +S     ++++E RE++ K+  E+ KR  +  +
Sbjct: 506 QLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR--EEEKRLEQERR 563

Query: 449 EMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEI 508
           E    RE + ++  +  R          EE +R   +       Q ER+E++       +
Sbjct: 564 EQRLKREQEERRDQLLKR----------EEERRQQRL----KREQEERLEQR-------L 602

Query: 509 PKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTR 557
            +E+     + E R   E +L  + P EE+    L S      + +  R
Sbjct: 603 KREEVERLEQEERR---EQRLKREEPEEERRQQLLKSEEQEERRQQQLR 648



 Score = 35.8 bits (81), Expect = 0.29
 Identities = 33/195 (16%), Positives = 82/195 (42%), Gaps = 12/195 (6%)

Query: 360 QKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYT 419
           Q++  E   +    +  E+ +  ++L+ E+ ++++ +LK ++ +  +     ++RR+   
Sbjct: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ----EERREQRL 620

Query: 420 SDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEG 479
              + ++E R+++ K   ++ +R  +  +E  Q+R  Q  K      R         EE 
Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQ-QERREQRLKREEEEERLEQRLKREHEEE 679

Query: 480 KRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQS 539
           +R   +   E     ER++       S IPK      ++ + R +     P +   + + 
Sbjct: 680 RREQELAEEEQEQARERIK-------SRIPKWQWQLESEADARQSKVYSRPRKQEGQRRR 732

Query: 540 PASLSSLRSRSTQME 554
                  R R ++++
Sbjct: 733 QEQEEKRRRRESELQ 747



 Score = 35.4 bits (80), Expect = 0.37
 Identities = 28/124 (22%), Positives = 62/124 (50%), Gaps = 1/124 (0%)

Query: 377  EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQA 436
            E+ Q  RQ R  + ++ + QL+ Q+++ +    + + RR+      +++++ R+E E++ 
Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQ 1739

Query: 437  LEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSER 496
            L + +R  K  +E     E + Q+     R R +  ++ L + +R      S+ S +  R
Sbjct: 1740 LRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQ-EREEQQLRSQESDRKFR 1798

Query: 497  VEEK 500
             EE+
Sbjct: 1799 EEEQ 1802



 Score = 35.0 bits (79), Expect = 0.49
 Identities = 20/78 (25%), Positives = 45/78 (57%), Gaps = 4/78 (5%)

Query: 974  KSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQA-- 1031
            K  ++E   A  EE+ + QE +   D+ ++  D+ +  + ++W+++ +   E+++LQ+  
Sbjct: 140  KRQEQERELAEGEEQSEKQERLEQRDRQRR--DEELWRQRQEWQEREERRAEEEQLQSCK 197

Query: 1032 EAEEQKRPAEEQKRQAEI 1049
              E ++ P EEQ R+ E+
Sbjct: 198  GHETEEFPDEEQLRRREL 215



 Score = 35.0 bits (79), Expect = 0.49
 Identities = 22/97 (22%), Positives = 51/97 (52%), Gaps = 3/97 (3%)

Query: 388  EEMQKIKSQL--KEQDQKWQDDLAK-WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 444
            EE+Q+ + QL  +E++++ + +L + +++  +    + Q  +EE E+  +Q LE+  R  
Sbjct: 1114 EELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREE 1173

Query: 445  KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKR 481
            +  ++  +    + Q+     R R Y  ++ L+  KR
Sbjct: 1174 EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKR 1210



 Score = 35.0 bits (79), Expect = 0.49
 Identities = 28/153 (18%), Positives = 72/153 (47%), Gaps = 13/153 (8%)

Query: 377  EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQA 436
            ED Q   +   +++Q +  + +E+D+  + +  +W+ R + +  + Q ++EE++E +++ 
Sbjct: 1254 EDSQLRDRQSQQDLQHLLGEQQERDR--EQERRRWQQRDRHFPEEEQLEREEQKEAKRR- 1310

Query: 437  LEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSE- 495
                 R S+  K++L++   + ++     R+       + E  ++P      +  ++ E 
Sbjct: 1311 ----DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEE 1366

Query: 496  -RVEEKGATYPSEIPK----EDSTTFAKREDRV 523
             R +E+G  +  E  +    E    F K E ++
Sbjct: 1367 LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL 1399



 Score = 34.7 bits (78), Expect = 0.64
 Identities = 28/138 (20%), Positives = 63/138 (45%), Gaps = 14/138 (10%)

Query: 377  EDVQNLRQLRYEEMQKIKSQLKEQDQKW-------------QDDLAKWKDRRKSYTSDLQ 423
            E+ Q LRQ R+ + ++ +  L+E++++              +  L + +  RK    +L+
Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELR 1509

Query: 424  KKKEEREEIEK-QALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRP 482
             ++ ER+ +E+ Q L + +R  K  +E  Q R  +  +     R R +  ++ L + +  
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569

Query: 483  PTMTVSEASYQSERVEEK 500
              ++  E   +    E+K
Sbjct: 1570 QQLSRQERDRKFRLEEQK 1587



 Score = 34.7 bits (78), Expect = 0.64
 Identities = 39/199 (19%), Positives = 85/199 (42%), Gaps = 10/199 (5%)

Query: 379  VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALE 438
            +Q  +QLR +E+++   + +E++Q  Q+   +   R++ Y   L+++ + R E E+Q L 
Sbjct: 1710 LQEEQQLRRQELER---KFREEEQLRQETEQEQLRRQERYRKILEEE-QLRPEREEQQLR 1765

Query: 439  KSKRSSKTFKE--MLQDRESQNQKSTVPSR--RRMYSFDDVLEEGKRPPTMTVSEASYQS 494
            + +R  K  +E  + Q+RE Q  +S    R  R         EE +  P     +  ++ 
Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE 1825

Query: 495  ERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQME 554
            E+++ +       + +E    +   E   T E     +  + ++        R R  + E
Sbjct: 1826 EQLQLE--EQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREE 1883

Query: 555  STRVSASLPRSYRKTDTVR 573
              R      + +R+   ++
Sbjct: 1884 HIRRQQKEEQRHRQVGEIK 1902



 Score = 34.3 bits (77), Expect = 0.83
 Identities = 39/216 (18%), Positives = 90/216 (41%), Gaps = 15/216 (6%)

Query: 963  ATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQ- 1021
            A  +AT  +  K +  +G  +  ++RRQ +++   E + ++ +++    R +K ++Q + 
Sbjct: 88   ALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERE 147

Query: 1022 ----EEQEQKRLQAEAEEQKRPAEE-----QKRQAEIERETSVRIYQYRRPVDSYDIPKT 1072
                EEQ +K+ + E  +++R  EE     Q+ Q   ER       Q  +  ++ + P  
Sbjct: 148  LAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDE 207

Query: 1073 EEASSGFL-----PGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPS 1127
            E+     L      G   K +   E  D    +    ++  +   +   + + ++E+   
Sbjct: 208  EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267

Query: 1128 GAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1163
              EL+ ++      +R  L  +     Q+   + +E
Sbjct: 268  QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE 303



 Score = 34.3 bits (77), Expect = 0.83
 Identities = 28/99 (28%), Positives = 54/99 (54%), Gaps = 18/99 (18%)

Query: 377  EDVQNLRQLRYE-----EMQKIKSQLKEQ------DQKWQDD---LAKWKDRRKSYTSDL 422
            E+ Q LR+   E     E Q+++ Q +EQ      D+K++++   L++ +  RK    + 
Sbjct: 1378 EEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQ 1437

Query: 423  QKKKEERE----EIEKQALEKSKRSSKTFKEMLQDRESQ 457
            Q +++ERE    E E+Q  ++  R  +  +++LQ+RE Q
Sbjct: 1438 QVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQ 1476



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 27/117 (23%), Positives = 60/117 (51%), Gaps = 12/117 (10%)

Query: 365  ENGSKSMSDVSAEDVQNLRQLRYEEM-QKIKSQLKEQDQKWQDDLAKWKD----RRKSYT 419
            E   +   ++  E+ Q LR+ R +   Q+++ Q +E+++  Q++    ++    RR+   
Sbjct: 1107 ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQEL 1166

Query: 420  SDLQKKKEEREEIEKQAL--EKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDD 474
                +++EE ++ E+Q L  E+ KR  +  ++  ++ E Q QK     R++ Y  +D
Sbjct: 1167 ERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK-----RKQRYRDED 1218



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 37/241 (15%), Positives = 94/241 (39%), Gaps = 17/241 (7%)

Query: 343 WASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQ-- 400
           W   + +EAD   S+++ +   + G +   +   +  +   +L+++E ++   Q +E+  
Sbjct: 704 WQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763

Query: 401 ----DQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRES 456
                 +WQ   A+ K  R       +    E+ E + +A E+ +R  +   E  +  + 
Sbjct: 764 RRDFTWQWQ---AEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQR 820

Query: 457 QNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTF 516
           + Q+       +    ++ L+  +R   +   E   Q ++   +      E  ++    +
Sbjct: 821 RRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRS----QEQRRDQKWRW 876

Query: 517 AKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQME----STRVSASLPRSYRKTDTV 572
              E+R      L ++  ++EQ       L+    +++      R      R YR+ + +
Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936

Query: 573 R 573
           +
Sbjct: 937 Q 937



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 25/91 (27%), Positives = 51/91 (56%), Gaps = 10/91 (10%)

Query: 375  SAEDVQNL---RQLRYEEMQKIKSQLK-----EQDQKWQDDLAKWKDRRKSYTSDLQKKK 426
            S +D+Q+L   +Q R  E ++ + Q +     E++Q  +++  + K R +    + Q  +
Sbjct: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322

Query: 427  EEREEIEKQALEKSKRSSKTFKEMLQDRESQ 457
            EERE  EK+  +++ R  +  +++LQ+RE Q
Sbjct: 1323 EERE--EKRRRQETDRKFREEEQLLQEREEQ 1351



 Score = 32.7 bits (73), Expect = 2.4
 Identities = 32/166 (19%), Positives = 76/166 (45%), Gaps = 17/166 (10%)

Query: 377  EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQA 436
            + +++ R  ++ E +++  + +EQ  + Q+   K+++  +     L++++ ER+ ++++ 
Sbjct: 1659 QQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ----QLRRQERERKFLQEEQ 1714

Query: 437  LEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSER 496
              + +   + F+E  Q R+   Q+      RR   +  +LEE +  P     E   Q  R
Sbjct: 1715 QLRRQELERKFREEEQLRQETEQEQL----RRQERYRKILEEEQLRP-----EREEQQLR 1765

Query: 497  VEEKGATYPSE----IPKEDSTTFAKREDRVTTEIQLPSQSPVEEQ 538
             +E+   +  E      +E+    ++  DR   E +   Q   E+Q
Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQ 1811



 Score = 31.6 bits (70), Expect = 5.4
 Identities = 18/75 (24%), Positives = 44/75 (58%), Gaps = 3/75 (4%)

Query: 384  QLRYE-EMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKR 442
            QLR E E Q++  Q +++  + ++   + +++ + +  D Q+ +  R+E ++Q  ++  R
Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLR--RQEGQQQLRQERDR 1619

Query: 443  SSKTFKEMLQDRESQ 457
              +  +++LQ+RE Q
Sbjct: 1620 KFREDEQLLQEREEQ 1634


>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
            [Homo sapiens]
          Length = 899

 Score = 77.4 bits (189), Expect = 9e-14
 Identities = 94/392 (23%), Positives = 166/392 (42%), Gaps = 59/392 (15%)

Query: 769  EWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEK---SSNLSVTTDFSES 825
            E ++   +   + H   +++R   A S   K  D        E+   S  L   T  +E 
Sbjct: 163  ESKDLAGRLHHSWHFAGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEE 222

Query: 826  LQSSNIESKEINGIHDESNAFESKASE-SISLKNLKRRSQFFEQGSSDSVVPDLPVPTIS 884
            L+  N E +E      +    ES+ SE  +++K LKR+ +      +  ++P +   T+ 
Sbjct: 223  LKKKNAELQE------KLPLAESEKSEIQLNVKELKRKLE-----RAKFLLPQVQTNTLQ 271

Query: 885  APSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAE---------R 935
                 +W QEEE + QE+  ++Q+    EK  R++E+LRE+  + +++ E         R
Sbjct: 272  EE---MWRQEEELREQEKKIRKQE----EKMWRQEERLREQEGKMREQEEKMWRQEKRLR 324

Query: 936  ENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEV 995
            E  K L E+   L          E      E  W +  K  ++E     +EER   QE+ 
Sbjct: 325  EQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 384

Query: 996  VHEDQGKKPQDQLVIERERKWEQ--QLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1053
            + E Q +K +DQ     ER WEQ  +L+E++E+ R Q +  EQ     E+K+  E E+  
Sbjct: 385  MRE-QEQKMRDQ----EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEK-- 437

Query: 1054 SVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNM 1113
                             KT +        +R + R     ++  T +    K   Q  NM
Sbjct: 438  -----------------KTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 480

Query: 1114 TSSQRRS-KKEQVPSGAE-LERQQILQEMRKR 1143
               + +  +++++P   E L  Q+ +QE  ++
Sbjct: 481  WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512



 Score = 74.7 bits (182), Expect = 6e-13
 Identities = 46/171 (26%), Positives = 90/171 (52%), Gaps = 4/171 (2%)

Query: 890  VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAE-RENSKYLDEELMVL 948
            +W+QEE+ + QE+   +Q+  +++K Q +++K  ++ ++ ++E   RE  K + EE  ++
Sbjct: 546  MWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 605

Query: 949  SSNSMSLTTREPSLATWEAT-WSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQ 1007
                  +  +E  +   E   W +  K  ++E     +EE+   QEE + E Q    Q +
Sbjct: 606  REQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKE 665

Query: 1008 LVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKR--QAEIERETSVR 1056
             + E E+  EQ+  +EQE+K  + E  E+K   +E+K   Q ++  E S+R
Sbjct: 666  KLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR 716



 Score = 70.1 bits (170), Expect = 1e-11
 Identities = 46/176 (26%), Positives = 86/176 (48%), Gaps = 13/176 (7%)

Query: 890  VWDQEEERKRQER--WQKEQDRLLQEKYQREQEKLREEWQRA-KQEAERENSKYLDEELM 946
            +W+QEE+ + QE   W++E+    QE+   EQ++L E+ ++  + E  +E  K  ++E  
Sbjct: 626  MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEK 685

Query: 947  VLSSNSMSLTTREPSLATWEAT-WSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK--- 1002
            +     M   T+E    TW+     E     +RE     EEE  + QEE + E + K   
Sbjct: 686  IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQE 745

Query: 1003 ------KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052
                  + ++++  + E+ WEQQ   EQ++K  + E  +++    EQ+ +   + E
Sbjct: 746  QEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEE 801



 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 62/269 (23%), Positives = 125/269 (46%), Gaps = 23/269 (8%)

Query: 890  VWDQEEERKRQER-WQKEQD-RLLQEKYQREQEKLREEWQRAKQEA--ERENSKYLDEEL 945
            +W+QE+ ++++E+ W++E+  R  +E + +E++  R+E  R +++   E+E      E+ 
Sbjct: 500  LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 559

Query: 946  MVLSSNSMSLTTREPSLATW--EATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003
            M      M   T+E    TW  E    E  +  +RE     EEE  + QEE + E Q +K
Sbjct: 560  MWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE-QEEK 618

Query: 1004 PQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP 1063
             Q+Q     E+ WEQ+ ++ QEQ+    E EE+    EE+  + +   E   +++++ + 
Sbjct: 619  MQEQ----EEKMWEQE-EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 673

Query: 1064 VDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKE 1123
             +   + + EE        ++ K    T+  +  T         +++    S + R KK 
Sbjct: 674  QEQEKMQEQEEKI-----WEQEKMEKKTQEQEKKTWDQ------EKMREEESMREREKKM 722

Query: 1124 QVPSGAELERQQILQEMRKRTPLHNDNSW 1152
            +       E+++ +QE  ++     +  W
Sbjct: 723  REEEEMMREQEEKMQEQEEKMQEQEEEMW 751



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 67/287 (23%), Positives = 124/287 (43%), Gaps = 39/287 (13%)

Query: 890  VWDQEEERKRQERWQK-------EQDRLLQEKYQR--EQEKLREEWQRAKQEAERENSKY 940
            +W+QE++ + QE+  +       EQD  L+EK +R  EQEK+ E+ ++ ++E + +  + 
Sbjct: 378  LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEK 437

Query: 941  LDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ 1000
               +             +E  +   E       K  + E T   +EE+ Q QEE + E +
Sbjct: 438  KTRD-------------QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 484

Query: 1001 GKKPQDQ-LVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQ 1059
             K+ Q Q L  ++E+ WEQ+  +EQE+K    E EE+ R  EE   Q +       ++++
Sbjct: 485  EKEWQQQRLPEQKEKLWEQEKMQEQEEKIW--EQEEKIRDQEEMWGQEK-------KMWR 535

Query: 1060 YRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQR- 1118
              +  +  D    +E     +     K     E  +  T +    K  DQ   M   +R 
Sbjct: 536  QEKMREQEDQMWEQEEK---MRDQEQKMWDQEERMEKKTQEQ-EKKTWDQEEKMREEERM 591

Query: 1119 --RSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1163
              R KK +       E+++ +QE  ++     +  W ++      +E
Sbjct: 592  REREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638



 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 47/182 (25%), Positives = 86/182 (47%), Gaps = 23/182 (12%)

Query: 891  WDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS 950
            WDQE+ R+ +   ++E+    +E+  REQE+  +E +   QE E E   +  EE M    
Sbjct: 704  WDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEE--MWEQEEKMWEQE 761

Query: 951  NSMSLTTREPS----------LATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ 1000
              M    R P           +   E  W +  K  D+E    G+EE+ + QEE +   +
Sbjct: 762  EKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821

Query: 1001 GKK--PQDQLVIERERKWEQQL----QEEQEQKRLQAEAE-----EQKRPAEEQKRQAEI 1049
             K    ++++  + E+ W Q+     QEE+ ++++Q + E     E+K   +E+K + + 
Sbjct: 822  EKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQE 881

Query: 1050 ER 1051
            E+
Sbjct: 882  EK 883



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 60/274 (21%), Positives = 117/274 (42%), Gaps = 31/274 (11%)

Query: 892  DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAER--ENSKYLDEELMVLS 949
            ++EE  + QE+  ++ +++ +EK  +EQEK   + +   QE ER  E  K + EE   + 
Sbjct: 408  EKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMR 467

Query: 950  SNSMSLTTREPSLATWEAT---WSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQD 1006
                 +  +E ++  WE     W +      +E  +  E+E+ Q QEE + E      Q+
Sbjct: 468  EQEEKMQKQEENM--WEQEEKEWQQQRLPEQKE--KLWEQEKMQEQEEKIWE------QE 517

Query: 1007 QLVIERERKWEQQ----LQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRR 1062
            + + ++E  W Q+     QE+  ++  Q   +E+K   +EQK   + ER       Q ++
Sbjct: 518  EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKK 577

Query: 1063 PVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKK 1122
              D  +  + EE         R + R     ++    +    K  +Q   M   Q + +K
Sbjct: 578  TWDQEEKMREEE---------RMREREKKMREEEEMMREQEEKMQEQEEKM---QEQEEK 625

Query: 1123 EQVPSGAELERQQILQEMRKRTPLHNDNSWIRQR 1156
                     E+++ + E  ++     +  W +QR
Sbjct: 626  MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659



 Score = 60.8 bits (146), Expect = 8e-09
 Identities = 43/179 (24%), Positives = 87/179 (48%), Gaps = 23/179 (12%)

Query: 890  VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREE----WQRAKQE--AERENSKYLDE 943
            +W+QEE+   Q+R  +++++L + +  +EQEK++E+    W++ K E   + +  K  D+
Sbjct: 647  MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ 706

Query: 944  ELMVLSSNSMSLTTREPSLATWEATWSEGS-KSSDREGTRAGEEERRQPQEEVVHEDQGK 1002
            E M       S+  RE  +   E    E   K  ++E     +EE    QEE + E + K
Sbjct: 707  EKM---REEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK 763

Query: 1003 KPQDQLVIER-------------ERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAE 1048
              + Q + E+             E+ WEQ+ +   ++++++ + E+ +   E+ + Q E
Sbjct: 764  MWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEE 822



 Score = 57.0 bits (136), Expect = 1e-07
 Identities = 60/302 (19%), Positives = 129/302 (42%), Gaps = 40/302 (13%)

Query: 893  QEEERKRQE----RWQKEQDRLLQEKYQREQEKLRE----EWQRAK-----------QEA 933
            QEEER R+     R ++E  R  +EK Q+++E + E    EWQ+ +           ++ 
Sbjct: 447  QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 506

Query: 934  ERENSKYLDEELMVLSSNSM-----SLTTREPSLATWEATWSEGSKSSDREGTRAGEEER 988
            + +  K  ++E  +     M      +  +E      +  W +  K  D+E     +EER
Sbjct: 507  QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 566

Query: 989  ----RQPQEEVVHEDQGKKPQDQLVIERERKW--EQQLQEEQEQKRLQAEAEEQKRPAEE 1042
                 Q QE+   + + K  +++ + ERE+K   E+++  EQE+K +Q + E+ +   E+
Sbjct: 567  MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK-MQEQEEKMQEQEEK 625

Query: 1043 QKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNG 1102
               Q E  +E   ++++    +   +    E+     LP  + K     ++ +    +  
Sbjct: 626  MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR---LPEQKEKLWEHEKMQEQEKMQEQ 682

Query: 1103 NNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKR-TPLHNDNSWIRQRSASVN 1161
              K  +Q         +  +EQ     + E+ +  + MR+R   +  +   +R++   + 
Sbjct: 683  EEKIWEQ-----EKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQ 737

Query: 1162 KE 1163
            ++
Sbjct: 738  EQ 739



 Score = 55.8 bits (133), Expect = 3e-07
 Identities = 38/144 (26%), Positives = 75/144 (52%), Gaps = 12/144 (8%)

Query: 890  VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLS 949
            +W+QEE+   Q+R  +++++L + +  +EQEK+ E+ ++ + + E+   +   EE M   
Sbjct: 757  MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ---EEKMRGQ 813

Query: 950  SNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHED-QGKKPQDQL 1008
               M            E  W +  K   +E    G+EE+   QEE + E  QG++ + + 
Sbjct: 814  EEKMR--------GQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMRE 865

Query: 1009 VIERERKWEQQLQEEQEQKRLQAE 1032
              E+ R  E++++E++E+ R Q E
Sbjct: 866  QEEKMRGQEEKMREQEEKMRGQEE 889



 Score = 40.0 bits (92), Expect = 0.015
 Identities = 30/189 (15%), Positives = 89/189 (47%), Gaps = 14/189 (7%)

Query: 380 QNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK-W--KDRRKSYTSDLQKKKEEREE--IEK 434
           Q  +  R E+M++ + Q+ EQ++K +D   K W  ++R +  T + +KK  ++EE   E+
Sbjct: 529 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREE 588

Query: 435 QALEKSKRSSKTFKEMLQDRE---SQNQKSTVPSRRRMYSFDDVLEE------GKRPPTM 485
           + + + ++  +  +EM++++E    + ++       +M+  ++ ++E       +     
Sbjct: 589 ERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMW 648

Query: 486 TVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSS 545
              E  ++ +R+ E+          ++     ++E+++  + ++  ++  +E+       
Sbjct: 649 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEK 708

Query: 546 LRSRSTQME 554
           +R   +  E
Sbjct: 709 MREEESMRE 717



 Score = 38.9 bits (89), Expect = 0.034
 Identities = 28/148 (18%), Positives = 73/148 (49%), Gaps = 9/148 (6%)

Query: 360 QKIYGENGSKSMSDVSAEDVQNLR---QLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRK 416
           +K++ +   +   D   E  + +R   Q  +++ ++++ + +EQ++K  D   K ++  +
Sbjct: 531 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER 590

Query: 417 SYTSDLQKKKEE---REEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTV-PSRRRMYSF 472
               + + ++EE   RE+ EK   ++ K   +  K   Q+ + Q Q+  +     +M+  
Sbjct: 591 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650

Query: 473 DDVLEEGKRPPTMTVSEASYQSERVEEK 500
           ++ + E +R P     E  ++ E+++E+
Sbjct: 651 EEKMWEQQRLPEQ--KEKLWEHEKMQEQ 676



 Score = 37.4 bits (85), Expect = 0.098
 Identities = 30/162 (18%), Positives = 75/162 (46%), Gaps = 13/162 (8%)

Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER--------EEIEKQALEK 439
           E+MQ+ + ++ EQ++K +D    W   +K +  +  +++E++         + E++  ++
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 563

Query: 440 SKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVL---EEGKRPPTMTVSEASYQSER 496
            +R  K  +E  Q++++ +Q+  +    RM   +  +   EE  R     + E   + + 
Sbjct: 564 EERMEKKTQE--QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621

Query: 497 VEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQ 538
            EEK      ++ +++   + + E     E ++  Q  + EQ
Sbjct: 622 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQ 663



 Score = 36.2 bits (82), Expect = 0.22
 Identities = 27/124 (21%), Positives = 59/124 (47%), Gaps = 13/124 (10%)

Query: 389 EMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFK 448
           E +K++ + +EQ++K  D   + K R +    + +KK  E EE+ ++  EK +   +  +
Sbjct: 688 EQEKMEKKTQEQEKKTWD---QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQ 744

Query: 449 EMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEI 508
           E  ++   Q +K        M+  ++ + E +R P     E  ++ E+++E+   +  E 
Sbjct: 745 EQEEEMWEQEEK--------MWEQEEKMWEQQRLPEQ--KEKLWEHEKMQEQEKIWEQEE 794

Query: 509 PKED 512
              D
Sbjct: 795 KMRD 798



 Score = 35.8 bits (81), Expect = 0.29
 Identities = 33/199 (16%), Positives = 91/199 (45%), Gaps = 9/199 (4%)

Query: 328 LRKKKPDKHEDNRRSWASPV-YTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLR 386
           LR+++    +   + W       E +G      +K++ +   K + +   E  +  ++LR
Sbjct: 281 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQE--KRLREQEKELREQEKELR 338

Query: 387 YE-EMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSK 445
            + E+++ + Q++EQ++K  +   K +++ +     + +++E   E EKQ  E+ ++   
Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMREQEEK----MWRQEERLWEQEKQMREQEQKMRD 394

Query: 446 TFKEML-QDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATY 504
             + M  QD   + ++  +  + +M+   + + E K+           + +  EE+    
Sbjct: 395 QEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRE 454

Query: 505 PSEIPKEDSTTFAKREDRV 523
             +  +E+  T  ++E+++
Sbjct: 455 REKKMREEEETMREQEEKM 473



 Score = 35.4 bits (80), Expect = 0.37
 Identities = 28/165 (16%), Positives = 75/165 (45%), Gaps = 5/165 (3%)

Query: 360 QKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQ-KWQDDLAKWKDRRKSY 418
           +K+  E   +       E+ + +R+ + E+MQ+ + +++EQ++  W+ +    +   K +
Sbjct: 583 EKMREEERMREREKKMREEEEMMRE-QEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMW 641

Query: 419 TSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEE 478
             + +  ++E +  E+Q L + K      ++M +  + Q Q+  +  + +M   +   +E
Sbjct: 642 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKM---EKKTQE 698

Query: 479 GKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRV 523
            ++           +S R  EK      E+ +E      ++E+++
Sbjct: 699 QEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKM 743



 Score = 35.4 bits (80), Expect = 0.37
 Identities = 14/46 (30%), Positives = 32/46 (69%)

Query: 890 VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAER 935
           +W QEE+ + + + Q+E+ R  +EK + ++EK+RE+ ++ + + E+
Sbjct: 845 MWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890



 Score = 34.7 bits (78), Expect = 0.64
 Identities = 31/155 (20%), Positives = 74/155 (47%), Gaps = 11/155 (7%)

Query: 388 EEMQKIKSQLKEQDQKWQDDLAK-WKDRRKSYTSDLQKKKEER--EEIEKQALEKSKRSS 444
           E + + + Q++EQ+QK +D   + W+   +    + + +++E+  E++EK   EK K   
Sbjct: 376 ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEK-KMQE 434

Query: 445 KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEE-----GKRPPTM-TVSEASYQSERV- 497
           +  K   Q+ + Q ++      ++M   ++ + E      K+   M    E  +Q +R+ 
Sbjct: 435 QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 494

Query: 498 EEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQ 532
           E+K   +  E  +E      ++E+++  + ++  Q
Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ 529



 Score = 34.7 bits (78), Expect = 0.64
 Identities = 18/124 (14%), Positives = 62/124 (50%), Gaps = 1/124 (0%)

Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQA 436
           E  Q +R  + E M +   +L+E++++ ++    W+   K       +++E++   +++ 
Sbjct: 387 EQEQKMRD-QEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445

Query: 437 LEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSER 496
           +++ +R  +  K+M ++ E+  ++     ++    ++   +E ++       E  ++ E+
Sbjct: 446 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 505

Query: 497 VEEK 500
           ++E+
Sbjct: 506 MQEQ 509



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 19/95 (20%), Positives = 53/95 (55%), Gaps = 4/95 (4%)

Query: 388 EEMQKIKSQLKEQDQK---WQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 444
           EEM + + +L+EQ++K    ++ + + ++R +     +++++E+    EK+  E+ K   
Sbjct: 272 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELR 331

Query: 445 KTFKEMLQDRESQNQKSTVPSR-RRMYSFDDVLEE 478
           +  KE+ + +E + Q+  +  +  +M+  ++ + E
Sbjct: 332 EQEKELREQKELREQEEQMQEQEEKMWEQEEKMRE 366



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 24/161 (14%), Positives = 77/161 (47%), Gaps = 11/161 (6%)

Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQK--------WQDDLAKWKDRRKSYTSDLQKKKEE 428
           ++ + +R+ R ++M++ +  ++EQ++K        W+ +  +W+ +R     +   ++E+
Sbjct: 447 QEEERIRE-REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 505

Query: 429 REEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVS 488
            +E E++  E+ ++     +   Q+++   Q+       +M+  ++ + + ++   M   
Sbjct: 506 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ--KMWDQ 563

Query: 489 EASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQL 529
           E   + +  E++  T+  E    +     +RE ++  E ++
Sbjct: 564 EERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 604



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 31/173 (17%), Positives = 73/173 (42%), Gaps = 10/173 (5%)

Query: 330 KKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEE 389
           K +    E  +++W      E +    R       E   +   ++  E  + +++ + E+
Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMRER-------EKKMREEEEMMREQEEKMQE-QEEK 742

Query: 390 MQKIKSQLKEQDQK-WQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFK 448
           MQ+ + ++ EQ++K W+ +   W+ +R     +   + E+ +E EK   ++ K   +  K
Sbjct: 743 MQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEK 802

Query: 449 EMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASY-QSERVEEK 500
              Q+ + + Q+  +  +       +    G+        E  + Q E++EEK
Sbjct: 803 MRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEK 855



 Score = 32.0 bits (71), Expect = 4.1
 Identities = 31/162 (19%), Positives = 79/162 (48%), Gaps = 36/162 (22%)

Query: 388 EEMQKIKSQLKEQDQK-WQDDLAKWKDRRKSYTSD-------------LQKKKE---ERE 430
           E+MQ+ + ++ EQ++K W+ +   W+ +R     +             +Q+++E   E+E
Sbjct: 631 EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE 690

Query: 431 EIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEA 490
           ++EK+  E+ K++    +E +++ ES  ++      ++M   ++++ E +        + 
Sbjct: 691 KMEKKTQEQEKKTWD--QEKMREEESMRER-----EKKMREEEEMMREQE-------EKM 736

Query: 491 SYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQ 532
             Q E+++E+      E   E      ++E+++  + +LP Q
Sbjct: 737 QEQEEKMQEQ-----EEEMWEQEEKMWEQEEKMWEQQRLPEQ 773


>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
            sapiens]
          Length = 750

 Score = 75.5 bits (184), Expect = 3e-13
 Identities = 66/321 (20%), Positives = 133/321 (41%), Gaps = 24/321 (7%)

Query: 890  VWDQEEERKRQERWQKEQDRLL--QEKYQREQEKLREEWQRAKQEAERENSKYLDEELMV 947
            +W QEE+ + QE   +EQ++ +  QE+   EQEK+REE +R +QE      + + E+  +
Sbjct: 432  MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491

Query: 948  LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQ 1007
                       E      E  W +  K  ++E     +EE+   QEE + E +    +++
Sbjct: 492  WRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551

Query: 1008 LVIERERKWEQQLQEEQEQK------RLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYR 1061
             + E+E+ WE++ ++EQE K      +++ + E+  R  E+ + Q E  +E   ++++  
Sbjct: 552  KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE 611

Query: 1062 RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNG--NNKYLDQIGNMTSSQ-- 1117
              +   +    E+     +     K R   E+      K G    K  +Q   M   +  
Sbjct: 612  EKIREQEEKIQEQEEK--IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET 669

Query: 1118 --RRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGE 1175
              R+ +K +       E+++ ++E  +      +  W ++      +E +         E
Sbjct: 670  MWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ--------E 721

Query: 1176 SLDNLDSPRSNSWRQPPWLNQ 1196
              + +       W Q   L Q
Sbjct: 722  QEEKMRRQEEKMWEQEVRLRQ 742



 Score = 69.7 bits (169), Expect = 2e-11
 Identities = 52/179 (29%), Positives = 90/179 (50%), Gaps = 14/179 (7%)

Query: 890  VWDQEEERKRQER--WQKEQDRLLQEKYQREQEKLRE-EWQRAKQEAERENSKYLDEELM 946
            +W++EE+ +RQE   W+KE+     E+   EQEK+RE E +R ++E  RE  K  ++E  
Sbjct: 372  MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 431

Query: 947  VLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQD 1006
            +           E      +  W +  K  ++E  R  EEE+RQ QEE+         Q+
Sbjct: 432  MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR--EEEKRQEQEEMWR-------QE 482

Query: 1007 QLVIERERKWEQ-QLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPV 1064
            + + E+E  W Q +   EQE+K ++ + E+  R  E+ + Q E  RE   ++++    +
Sbjct: 483  EKIHEQEEIWRQKEKMHEQEEK-IRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540



 Score = 68.9 bits (167), Expect = 3e-11
 Identities = 49/192 (25%), Positives = 101/192 (52%), Gaps = 14/192 (7%)

Query: 890  VWDQEEERKRQER-W-QKEQDRLLQEKYQREQEKLREEWQRAKQEAE---RENSKYLDEE 944
            +W++E+ ++++++ W Q+E+ R  +EK  R++EK+RE+ ++ +++ E   ++  K  ++E
Sbjct: 559  IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618

Query: 945  LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-K 1003
              +           E      E T  +  K  ++E     +EE+ Q QEE +   + K +
Sbjct: 619  EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678

Query: 1004 PQDQLVIERE---RKWEQQLQEEQ----EQKRLQAEAEEQKRPAEEQ-KRQAEIERETSV 1055
             Q++ + E+E   R+ E+ +QE++    EQ+    E EE+ +  EE+ +RQ E   E  V
Sbjct: 679  EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738

Query: 1056 RIYQYRRPVDSY 1067
            R+ Q    +  +
Sbjct: 739  RLRQQEEKMQEH 750



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 55/235 (23%), Positives = 116/235 (49%), Gaps = 20/235 (8%)

Query: 832  ESKEING-IHDESNAFESKASE-SISLKNLKRRSQFFE--------QGSSDSVVPDLPVP 881
            E KE N  + ++    ES+ SE  +++K LKR+ +  +        Q  +D +  +L   
Sbjct: 218  ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277

Query: 882  TISAPSRW----VWDQEEERKRQERW-QKEQDRLLQEKYQREQEKLREEWQRAKQEAE-- 934
            +    ++     +W++  +++ ++ W Q+E+ +  +EK Q ++EK+RE+ ++ +++ E  
Sbjct: 278  SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337

Query: 935  -RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE 993
             R+     ++E  +     M     E      E  W +  K   +E     +EE+ +  E
Sbjct: 338  RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 397

Query: 994  EVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQK--RLQAEAEEQKRPAEEQKRQ 1046
            E +HE +  + Q++   E E+  EQ+ ++EQE K  R + +  EQ+    EQ+++
Sbjct: 398  EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 44/162 (27%), Positives = 84/162 (51%), Gaps = 15/162 (9%)

Query: 892  DQEEERKRQER--WQKEQDRLLQEKYQREQEKL--REEWQRAKQEAERENSKYLDEELMV 947
            +QEE+ +RQE   W+KE      EK +R++E +  +EE  R ++E   E  + +  +  +
Sbjct: 332  EQEEKMRRQEEMMWEKE------EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 385

Query: 948  LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQD 1006
            +      +   E  +   E    +  K  + E  R  E+E+RQ QE  +   + K + Q+
Sbjct: 386  MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR--EQEKRQEQEAKMWRQEEKIREQE 443

Query: 1007 QLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAE 1048
            + + E+E+K  +Q ++  EQ++++   EE+++  EE  RQ E
Sbjct: 444  EKIREQEKKMWRQEEKIHEQEKIR--EEEKRQEQEEMWRQEE 483



 Score = 38.9 bits (89), Expect = 0.034
 Identities = 29/176 (16%), Positives = 79/176 (44%), Gaps = 7/176 (3%)

Query: 331 KKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEM 390
           ++ +K  +  + W      E +    R  +KI  +       +    + +  RQ + E+M
Sbjct: 548 REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607

Query: 391 QKIKSQLKEQDQKWQDDLAKWKDR------RKSYTSDLQKKKEEREEIEKQALEKSKRSS 444
            K + +++EQ++K Q+   K +++      ++  T + ++K  E+EE   +  EK +   
Sbjct: 608 WKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667

Query: 445 KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 500
           +T     +++  + +K       ++   +++++E +        +   Q E+++E+
Sbjct: 668 ETMWRQ-EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 722



 Score = 37.0 bits (84), Expect = 0.13
 Identities = 30/159 (18%), Positives = 70/159 (44%), Gaps = 9/159 (5%)

Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEERE---EIE 433
           E +    ++R EE ++ + ++  Q++K  +    W+ + K +  + + +K+E +   + E
Sbjct: 458 EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE 517

Query: 434 KQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQ 493
           K   ++ K   +  K   Q+ + + Q+       +M+  + + EE KR       E   +
Sbjct: 518 KIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKR------QEQEDK 571

Query: 494 SERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQ 532
             R EEK      ++ +++     + E R   E ++  Q
Sbjct: 572 MWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610



 Score = 35.0 bits (79), Expect = 0.49
 Identities = 33/174 (18%), Positives = 83/174 (47%), Gaps = 17/174 (9%)

Query: 377 EDVQNLRQLRYEEMQKIKSQ---LKEQDQKW--QDDLAKWKDRRKSYTSDLQKKKEEREE 431
           E +Q   +   E+ +KI+ Q   ++EQ++K   Q+++   K+ +     ++  +KEE+  
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366

Query: 432 IEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLE-EGKRPPTMTVSEA 490
            +++ + + +   +  +EM+ ++E + ++       +M+  + + E E KR     + E 
Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRE----LEEKMHEQEKIREQEEKRQEEEKIREQ 422

Query: 491 SYQSE------RVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQ 538
             + E      R EEK      +I +E      ++E+++  + ++  +   +EQ
Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKI-REQEKKMWRQEEKIHEQEKIREEEKRQEQ 475



 Score = 34.3 bits (77), Expect = 0.83
 Identities = 29/149 (19%), Positives = 67/149 (44%), Gaps = 14/149 (9%)

Query: 386 RYEEM--QKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRS 443
           R EEM  +K +   ++++  W+ +    +   K +  +  +++EE+ + E++  E+ KR 
Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 426

Query: 444 SKTFKEMLQDRESQNQKSTVPSR--------RRMYSFDDVLEEGKRPPTMTVSEASYQSE 495
            +  K   Q+ + + Q+  +  +         +++  + + EE KR       E   Q E
Sbjct: 427 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR---QEQEEMWRQEE 483

Query: 496 RVEEKGATY-PSEIPKEDSTTFAKREDRV 523
           ++ E+   +   E   E      K+E++V
Sbjct: 484 KIHEQEEIWRQKEKMHEQEEKIRKQEEKV 512



 Score = 34.3 bits (77), Expect = 0.83
 Identities = 28/153 (18%), Positives = 72/153 (47%), Gaps = 23/153 (15%)

Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK------WKDRRKSYTSDLQKKKEERE 430
           E  + +R+ + E+M + + +++EQ++ W+++         W++ ++    D   ++EE+ 
Sbjct: 521 EQEEKIRE-QEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEK- 578

Query: 431 EIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEA 490
            I +Q  EK  R  +  +E  + R+ Q +K        M+  ++ + E +        + 
Sbjct: 579 -IREQE-EKVWRQEEKIREQEEKRQEQEEK--------MWKQEEKIREQEEKIQEQEEKI 628

Query: 491 SYQSERVEEKGATYPSEIPKEDSTTFAKREDRV 523
             Q E++ E+      E+ +E      ++E+++
Sbjct: 629 REQEEKIREQ-----EEMTQEQEEKMGEQEEKM 656



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 31/198 (15%), Positives = 84/198 (42%), Gaps = 7/198 (3%)

Query: 334 DKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDV----QNLRQLRYEE 389
           +K E  RR     +  E +     L +K++ +   +   +   E+     Q  RQ +  +
Sbjct: 374 EKEEKMRRQ--EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 431

Query: 390 MQKIKSQLKEQDQKWQDDLAK-WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFK 448
           M + + +++EQ++K ++   K W+   K +  +  +++E+R+E E+   ++ K   +   
Sbjct: 432 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491

Query: 449 EMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEI 508
              +++  + ++       +++  ++ + E +        +   Q E++ E+   +  E 
Sbjct: 492 WRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551

Query: 509 PKEDSTTFAKREDRVTTE 526
              +     + E R   E
Sbjct: 552 KMHEQEKIWEEEKRQEQE 569



 Score = 32.7 bits (73), Expect = 2.4
 Identities = 24/136 (17%), Positives = 63/136 (46%), Gaps = 12/136 (8%)

Query: 377 EDVQNLRQLRYEEMQKIKSQ----------LKEQDQKWQDDLAK-WKDRRKSYTSDLQKK 425
           E++   ++  +E+ +KI+ Q          ++EQ++K ++   K W+   K    +   +
Sbjct: 489 EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWR 548

Query: 426 KEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTV-PSRRRMYSFDDVLEEGKRPPT 484
           +EE+   +++  E+ KR  +  K   Q+ + + Q+  V     ++   ++  +E +    
Sbjct: 549 EEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW 608

Query: 485 MTVSEASYQSERVEEK 500
               +   Q E+++E+
Sbjct: 609 KQEEKIREQEEKIQEQ 624


>gi|239745153 PREDICTED: similar to Putative golgin subfamily A member
            6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 73.9 bits (180), Expect = 9e-13
 Identities = 46/189 (24%), Positives = 94/189 (49%), Gaps = 11/189 (5%)

Query: 892  DQEEERKRQERWQKEQDRLLQEKYQ---REQEKLREEWQRAKQEAERENSKYLDEELMVL 948
            +QEE+  RQE   +EQD  +QE+ +   R++EK+RE+ ++ +++  R+  K  +++  + 
Sbjct: 364  EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423

Query: 949  SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKP---- 1004
                      E      E    +  K  + E     EEE+ Q QEE +   + K      
Sbjct: 424  EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE 483

Query: 1005 ----QDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQY 1060
                Q++L+ + E+ WEQ+ +  ++++++  + E+ +   E+ +RQ E  RE  VR++Q 
Sbjct: 484  KTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQ 543

Query: 1061 RRPVDSYDI 1069
               +   ++
Sbjct: 544  EEKMQEQEV 552



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 39/178 (21%), Positives = 93/178 (52%), Gaps = 17/178 (9%)

Query: 890  VWDQEEERKRQERWQKEQD---RLLQEKYQREQEKLREEWQRAKQEAE---RENSKYLDE 943
            +W QEE+ + QE    EQ+   R  +EK  R++EK+ E+ ++ +++ +   R+  K  ++
Sbjct: 299  MWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ 358

Query: 944  ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003
            E  +       +  +E  +   +    E  +   R+  +  E+E ++ QE++  +++  +
Sbjct: 359  EEKIREQEE-KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKR-QEKMWRQEKKMR 416

Query: 1004 PQDQLVIERERK-WEQ--------QLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052
             QD+ + E+E + W Q        ++ ++QE+K  + E + Q+   + Q+++ +I+R+
Sbjct: 417  EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 52/204 (25%), Positives = 103/204 (50%), Gaps = 19/204 (9%)

Query: 892  DQEEERK----RQERWQKEQDRLLQEKYQ---REQEKLRE--EWQRAKQEAERENSKYLD 942
            +QEE+R+    RQE+  +EQD  ++E+ +   R++EK+RE  E  + ++E  RE  + + 
Sbjct: 399  EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458

Query: 943  EELMVLSSNSMSLTTREPSLATWEA-TW------SEGSKSSDREGTRAGEEERRQPQEEV 995
            EE   +      +  +E  +   E  TW       +  K  ++E     +EE+   QEE 
Sbjct: 459  EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518

Query: 996  VHEDQGK-KPQDQLVIERE-RKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1053
            + E + K + Q++ + E+E R W+Q+ + ++++ RLQ   E   +  ++ +      RE+
Sbjct: 519  MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRES 578

Query: 1054 SVRIYQYRRPVDSYDIPKTEEASS 1077
              +      P+   ++ K++EA S
Sbjct: 579  GSQRLPTLTPILQVEL-KSQEAQS 601



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 58/233 (24%), Positives = 105/233 (45%), Gaps = 31/233 (13%)

Query: 832  ESKEING-IHDESNAFESKASE-SISLKNLKR---RSQFFEQGSSDSVVPDLPVPTISAP 886
            E KE N  + ++    ES+ SE  +++K+LKR   R+Q         V  D     + + 
Sbjct: 215  ELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSV 274

Query: 887  SRWVWDQEEERKRQERWQKEQDRLL---QEKYQREQEKLREEWQRAKQEAERENSKYLDE 943
            S  +  Q EE +      ++Q+  +   +EK Q ++EK+ E+  + +   E+E   +  E
Sbjct: 275  SAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR---EQEEKMWRQE 331

Query: 944  ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003
            E M    +      RE     W             E  R  EE+ R+ +E++  +++  +
Sbjct: 332  EKM----HEQEEKIREQEDKMWR----------QEEKIREQEEKIREQEEKMWRQEEKIR 377

Query: 1004 PQDQLVIERERKWEQQLQE----EQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052
             QD+ + E+E   E   QE    EQE+KR +    ++K+  E+ ++  E E E
Sbjct: 378  EQDEKIQEQEE--EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE 428



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 22/54 (40%), Positives = 36/54 (66%), Gaps = 7/54 (12%)

Query: 890 VWDQEEERKRQER--WQKEQDRLLQ-EKYQREQEKLREE----WQRAKQEAERE 936
           +W+QEE+  RQE   W++E+    Q EK QR++EK+RE+    WQ+ ++  E+E
Sbjct: 498 IWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551



 Score = 35.8 bits (81), Expect = 0.29
 Identities = 32/188 (17%), Positives = 81/188 (43%), Gaps = 3/188 (1%)

Query: 368 SKSMSDVSAEDVQNL-RQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKK 426
           +K  + V   ++ NL  Q + E+M + + +++EQ++K  +   K +++ +      +K  
Sbjct: 276 AKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMH 335

Query: 427 EEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMT 486
           E+ E+I +Q  +K  R  +  +E  +    Q +K       ++   D+ ++E +      
Sbjct: 336 EQEEKIREQE-DKMWRQEEKIREQEEKIREQEEKMW-RQEEKIREQDEKIQEQEEEMWRQ 393

Query: 487 VSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSL 546
             +   Q E+ +EK      ++ ++D     + E+    E ++     + +     L  +
Sbjct: 394 EEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREV 453

Query: 547 RSRSTQME 554
             +  + E
Sbjct: 454 EEKMQEEE 461



 Score = 35.8 bits (81), Expect = 0.29
 Identities = 20/113 (17%), Positives = 57/113 (50%), Gaps = 3/113 (2%)

Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447
           EEM + + +++E ++  QD   K ++  +    + +K +E+ E+I++Q  +  ++  KT+
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486

Query: 448 KEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 500
           +   Q++  + ++       +M+  ++ + E +        +   Q E++ E+
Sbjct: 487 R---QEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQ 536



 Score = 32.0 bits (71), Expect = 4.1
 Identities = 18/89 (20%), Positives = 49/89 (55%), Gaps = 6/89 (6%)

Query: 377 EDVQNLRQLRYEEMQKIKSQ---LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIE 433
           E +Q   +   E+ +K   Q   LK++++ W+ +   W+   K +  + +K +E+ E+++
Sbjct: 469 EKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE-EKMQEQEEKMQ 527

Query: 434 KQALEKSKRSSKTF--KEMLQDRESQNQK 460
           +Q  +  ++  + +  +E +Q++E + Q+
Sbjct: 528 RQEEKMREQEVRLWQQEEKMQEQEVRLQE 556


>gi|239745127 PREDICTED: similar to Putative golgin subfamily A member
            6-like protein 6 [Homo sapiens]
          Length = 655

 Score = 73.9 bits (180), Expect = 9e-13
 Identities = 46/189 (24%), Positives = 94/189 (49%), Gaps = 11/189 (5%)

Query: 892  DQEEERKRQERWQKEQDRLLQEKYQ---REQEKLREEWQRAKQEAERENSKYLDEELMVL 948
            +QEE+  RQE   +EQD  +QE+ +   R++EK+RE+ ++ +++  R+  K  +++  + 
Sbjct: 364  EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423

Query: 949  SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKP---- 1004
                      E      E    +  K  + E     EEE+ Q QEE +   + K      
Sbjct: 424  EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE 483

Query: 1005 ----QDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQY 1060
                Q++L+ + E+ WEQ+ +  ++++++  + E+ +   E+ +RQ E  RE  VR++Q 
Sbjct: 484  KTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQ 543

Query: 1061 RRPVDSYDI 1069
               +   ++
Sbjct: 544  EEKMQEQEV 552



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 39/178 (21%), Positives = 93/178 (52%), Gaps = 17/178 (9%)

Query: 890  VWDQEEERKRQERWQKEQD---RLLQEKYQREQEKLREEWQRAKQEAE---RENSKYLDE 943
            +W QEE+ + QE    EQ+   R  +EK  R++EK+ E+ ++ +++ +   R+  K  ++
Sbjct: 299  MWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ 358

Query: 944  ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003
            E  +       +  +E  +   +    E  +   R+  +  E+E ++ QE++  +++  +
Sbjct: 359  EEKIREQEE-KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKR-QEKMWRQEKKMR 416

Query: 1004 PQDQLVIERERK-WEQ--------QLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052
             QD+ + E+E + W Q        ++ ++QE+K  + E + Q+   + Q+++ +I+R+
Sbjct: 417  EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 52/204 (25%), Positives = 103/204 (50%), Gaps = 19/204 (9%)

Query: 892  DQEEERK----RQERWQKEQDRLLQEKYQ---REQEKLRE--EWQRAKQEAERENSKYLD 942
            +QEE+R+    RQE+  +EQD  ++E+ +   R++EK+RE  E  + ++E  RE  + + 
Sbjct: 399  EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458

Query: 943  EELMVLSSNSMSLTTREPSLATWEA-TW------SEGSKSSDREGTRAGEEERRQPQEEV 995
            EE   +      +  +E  +   E  TW       +  K  ++E     +EE+   QEE 
Sbjct: 459  EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518

Query: 996  VHEDQGK-KPQDQLVIERE-RKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1053
            + E + K + Q++ + E+E R W+Q+ + ++++ RLQ   E   +  ++ +      RE+
Sbjct: 519  MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRES 578

Query: 1054 SVRIYQYRRPVDSYDIPKTEEASS 1077
              +      P+   ++ K++EA S
Sbjct: 579  GSQRLPTLTPILQVEL-KSQEAQS 601



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 58/233 (24%), Positives = 105/233 (45%), Gaps = 31/233 (13%)

Query: 832  ESKEING-IHDESNAFESKASE-SISLKNLKR---RSQFFEQGSSDSVVPDLPVPTISAP 886
            E KE N  + ++    ES+ SE  +++K+LKR   R+Q         V  D     + + 
Sbjct: 215  ELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSV 274

Query: 887  SRWVWDQEEERKRQERWQKEQDRLL---QEKYQREQEKLREEWQRAKQEAERENSKYLDE 943
            S  +  Q EE +      ++Q+  +   +EK Q ++EK+ E+  + +   E+E   +  E
Sbjct: 275  SAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR---EQEEKMWRQE 331

Query: 944  ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003
            E M    +      RE     W             E  R  EE+ R+ +E++  +++  +
Sbjct: 332  EKM----HEQEEKIREQEDKMWR----------QEEKIREQEEKIREQEEKMWRQEEKIR 377

Query: 1004 PQDQLVIERERKWEQQLQE----EQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052
             QD+ + E+E   E   QE    EQE+KR +    ++K+  E+ ++  E E E
Sbjct: 378  EQDEKIQEQEE--EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE 428



 Score = 41.2 bits (95), Expect = 0.007
 Identities = 22/54 (40%), Positives = 36/54 (66%), Gaps = 7/54 (12%)

Query: 890 VWDQEEERKRQER--WQKEQDRLLQ-EKYQREQEKLREE----WQRAKQEAERE 936
           +W+QEE+  RQE   W++E+    Q EK QR++EK+RE+    WQ+ ++  E+E
Sbjct: 498 IWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551



 Score = 35.8 bits (81), Expect = 0.29
 Identities = 32/188 (17%), Positives = 81/188 (43%), Gaps = 3/188 (1%)

Query: 368 SKSMSDVSAEDVQNL-RQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKK 426
           +K  + V   ++ NL  Q + E+M + + +++EQ++K  +   K +++ +      +K  
Sbjct: 276 AKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMH 335

Query: 427 EEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMT 486
           E+ E+I +Q  +K  R  +  +E  +    Q +K       ++   D+ ++E +      
Sbjct: 336 EQEEKIREQE-DKMWRQEEKIREQEEKIREQEEKMW-RQEEKIREQDEKIQEQEEEMWRQ 393

Query: 487 VSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSL 546
             +   Q E+ +EK      ++ ++D     + E+    E ++     + +     L  +
Sbjct: 394 EEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREV 453

Query: 547 RSRSTQME 554
             +  + E
Sbjct: 454 EEKMQEEE 461



 Score = 35.8 bits (81), Expect = 0.29
 Identities = 20/113 (17%), Positives = 57/113 (50%), Gaps = 3/113 (2%)

Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447
           EEM + + +++E ++  QD   K ++  +    + +K +E+ E+I++Q  +  ++  KT+
Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486

Query: 448 KEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 500
           +   Q++  + ++       +M+  ++ + E +        +   Q E++ E+
Sbjct: 487 R---QEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQ 536



 Score = 32.0 bits (71), Expect = 4.1
 Identities = 18/89 (20%), Positives = 49/89 (55%), Gaps = 6/89 (6%)

Query: 377 EDVQNLRQLRYEEMQKIKSQ---LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIE 433
           E +Q   +   E+ +K   Q   LK++++ W+ +   W+   K +  + +K +E+ E+++
Sbjct: 469 EKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE-EKMQEQEEKMQ 527

Query: 434 KQALEKSKRSSKTF--KEMLQDRESQNQK 460
           +Q  +  ++  + +  +E +Q++E + Q+
Sbjct: 528 RQEEKMREQEVRLWQQEEKMQEQEVRLQE 556


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
          Length = 570

 Score = 73.6 bits (179), Expect = 1e-12
 Identities = 48/186 (25%), Positives = 93/186 (50%), Gaps = 8/186 (4%)

Query: 890  VWDQEEERKRQERWQKEQDRLLQEKYQR---EQEKL---REEWQRAKQEAERENSKYLDE 943
            +W QEE+ + QE   +EQ+ ++QE+ ++   ++EK+    EE Q  +++  R+  K  ++
Sbjct: 385  MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ 444

Query: 944  ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK- 1002
            E  +           E      E    +  K  ++E     +EE+ + QEE + E + K 
Sbjct: 445  EKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKI 504

Query: 1003 KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQ-KRQAEIERETSVRIYQYR 1061
            + Q++ + E+E   ++Q ++  EQ+    E EE+ +  EE+ +RQ E  RE  VR+ Q  
Sbjct: 505  REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQE 564

Query: 1062 RPVDSY 1067
              +  +
Sbjct: 565  EKMQEH 570



 Score = 70.9 bits (172), Expect = 8e-12
 Identities = 49/188 (26%), Positives = 92/188 (48%), Gaps = 21/188 (11%)

Query: 890  VWDQEEERKRQER--WQKEQDRLLQEKYQREQEKLREEWQRAKQEAE------------- 934
            +W++EE+ +RQE   W+KE+     E+   EQEK+RE+ ++ ++E +             
Sbjct: 325  MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384

Query: 935  --RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQ 992
              R+  K  ++E  +     M     E      E  W +  +  ++E     +EE+ + Q
Sbjct: 385  MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ 444

Query: 993  EEVVHEDQGK-KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAE--- 1048
            E+ + E + K + Q++++ E+E K  +Q  +  EQ+    E EE+ R  EE+ R+ E   
Sbjct: 445  EKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKI 504

Query: 1049 IERETSVR 1056
             E+E  +R
Sbjct: 505  REQEEKIR 512



 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 47/184 (25%), Positives = 92/184 (50%), Gaps = 25/184 (13%)

Query: 890  VWDQEEERKRQERWQKEQDRLL-QEKYQREQEKLREEWQRAKQEAE--RENSKYLDEELM 946
            +W++EE+ +  E    EQ+++  QE+ ++E+EK+RE+ +R +QEA+  R+  K  ++E  
Sbjct: 339  MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 398

Query: 947  VLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQ 1005
            +     M     E      E  W +  +  ++E     +EE+ + QE+ + E + K + Q
Sbjct: 399  IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 458

Query: 1006 DQLVIERERKW-------------------EQQLQEE--QEQKRLQAEAEEQKRPAEEQK 1044
            ++++ E+E K                    + + QEE  +EQ++   E EE+ R  EE  
Sbjct: 459  EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 518

Query: 1045 RQAE 1048
            ++ E
Sbjct: 519  QEQE 522



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 60/254 (23%), Positives = 124/254 (48%), Gaps = 25/254 (9%)

Query: 832  ESKEING-IHDESNAFESKASE-SISLKNLKRRSQFFE--------QGSSDSVVPDLPVP 881
            E KE N  + ++    ES+ SE  +++K LKR+ +  +        Q  +D +  +L   
Sbjct: 206  ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 265

Query: 882  TISAPSRW----VWDQEEERKRQERW-QKEQDRLLQEKYQREQEKLREEWQRAKQEAE-- 934
            +    ++     +W++  +++ ++ W Q+E+ +  +EK Q ++EK+RE+ ++ +++ E  
Sbjct: 266  SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMM 325

Query: 935  --RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQ 992
              +E      EE+M        +   E  +   E    +  K  + E  R  E+E+RQ Q
Sbjct: 326  WEKEEKMRRQEEMMW--EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR--EQEKRQEQ 381

Query: 993  EEVVHEDQGK-KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQ-KRQAEIE 1050
            E  +   + K + Q++ + E+E   ++Q ++  EQ+    E EE+ +  EE+ +RQ E  
Sbjct: 382  EAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKI 441

Query: 1051 RETSVRIYQYRRPV 1064
            RE   +I +    +
Sbjct: 442  REQEKKIREQEEKI 455



 Score = 35.0 bits (79), Expect = 0.49
 Identities = 28/152 (18%), Positives = 70/152 (46%), Gaps = 6/152 (3%)

Query: 380 QNLRQLRYEEM--QKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQAL 437
           Q  +  R EEM  +K +   ++++  W+ +    +   K +  +  +++EE+ + E++  
Sbjct: 314 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 373

Query: 438 EKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERV 497
           E+ KR  +  K   Q+ + + Q+  +  +  M   +   + G++   M   E   Q +  
Sbjct: 374 EQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQ-EQEEKMGEQEEKMWEQEEEMQEQ-- 430

Query: 498 EEKGATYPSEIPKEDSTTFAKREDRVTTEIQL 529
           EEK      +I +E      ++E+++  + ++
Sbjct: 431 EEKMRRQEEKI-REQEKKIREQEEKIREQEEM 461



 Score = 32.3 bits (72), Expect = 3.2
 Identities = 26/147 (17%), Positives = 67/147 (45%), Gaps = 3/147 (2%)

Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447
           E+M + + +++EQ++K +    K +++ K      +K +E+ E +++Q  +  ++  K  
Sbjct: 418 EKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMC 477

Query: 448 KE--MLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYP 505
           ++   +Q++E + ++     R +     +  EE  R     + E   +    EEK     
Sbjct: 478 EQEAKMQEQEEKMRRQEEKIREQEKKIRE-QEEKIREQEEMMQEQEEKMWEQEEKMCEQE 536

Query: 506 SEIPKEDSTTFAKREDRVTTEIQLPSQ 532
            ++ +++     + E     E++L  Q
Sbjct: 537 EKMQEQEEKMRRQEEKMREQEVRLRQQ 563



 Score = 32.0 bits (71), Expect = 4.1
 Identities = 23/121 (19%), Positives = 56/121 (46%), Gaps = 2/121 (1%)

Query: 350 EADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLA 409
           E +    R  +KI  +       +    + + + Q + E+M + + ++ EQ+ K Q+   
Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488

Query: 410 KWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF--KEMLQDRESQNQKSTVPSRR 467
           K + + +      +K +E+ E+I +Q     ++  K +  +E + ++E + Q+     RR
Sbjct: 489 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 548

Query: 468 R 468
           +
Sbjct: 549 Q 549



 Score = 31.2 bits (69), Expect = 7.0
 Identities = 23/120 (19%), Positives = 59/120 (49%), Gaps = 8/120 (6%)

Query: 384 QLRYEEMQKIKSQLKEQDQKW--QDDLAKWKDRRKSYTSDLQKKKEER-EEIEKQALEKS 440
           Q R E++Q+ + +++EQ++K   Q+++   K+ +     ++  +KEE+  E+E++  E+ 
Sbjct: 298 QEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 357

Query: 441 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 500
           K   +  K   +++  + +K      +     + + E+ ++     + E     +  EEK
Sbjct: 358 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK-----IREQEEMMQEQEEK 412


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
            [Homo sapiens]
          Length = 828

 Score = 73.2 bits (178), Expect = 2e-12
 Identities = 75/332 (22%), Positives = 153/332 (46%), Gaps = 44/332 (13%)

Query: 761  KFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEK---SSNLS 817
            KF   +  E ++   +   + H   +++R   A S   K  D        E+   S  L 
Sbjct: 117  KFEDGNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELY 176

Query: 818  VTTDFSESLQSSNIESKEINGIHDESNAFESKASE-SISLKNLKRRSQFFEQGSSDSVVP 876
              T  +E L+  N E +E      +    ES+ SE  +++K LKR+ +      +  ++P
Sbjct: 177  RNTITNEELKKKNAELQE------KLRLAESEKSEIQLNVKELKRKLE-----RAKFLLP 225

Query: 877  DLPVPTISAPSRWVWDQEEE--------RKRQERWQKEQDRLLQ---------EKYQREQ 919
             +   T+      +W QEEE        RK++E+  ++++RL +         EK +R++
Sbjct: 226  QVQTNTLQEE---MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQE 282

Query: 920  EKLREEWQRAKQEAE--RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSD 977
            ++LRE+ +  +++ +  RE  K  ++E  +           E      E  W +  +  +
Sbjct: 283  KRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWE 342

Query: 978  REGTRAGEEERRQPQEEVVHE-DQGKKPQDQLVIERERKWEQQ--LQEE----QEQKRLQ 1030
            +E     +E++ + QEE + E D+  + +++ + E+E+ WEQ+  +QEE    + +K+++
Sbjct: 343  QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMR 402

Query: 1031 AEAEEQKRPAEEQKRQAEIERETSVRIYQYRR 1062
             E E  +   E+ ++Q E   E   + +Q +R
Sbjct: 403  EEEETMREQEEKMQKQEENMWEQEEKEWQQQR 434



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 59/212 (27%), Positives = 99/212 (46%), Gaps = 36/212 (16%)

Query: 891  WDQEE---------ERKRQERWQKEQDRLLQEKYQREQEKLREE----WQRAKQEAEREN 937
            WDQEE         ER+++ R ++E  R  +EK Q ++EK+RE+    W++ ++  E+E 
Sbjct: 550  WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609

Query: 938  SKYLDEELM--------VLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERR 989
              +  EE M        +     M     E      E  W +  K  ++E     +EE+ 
Sbjct: 610  KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 669

Query: 990  QPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAE---AEEQKRPAEEQKRQ 1046
            Q QEE + E Q +K Q Q         E++++E++E+ R Q E    +E+K   +E+K  
Sbjct: 670  QGQEEKMRE-QEEKMQGQ---------EEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMW 719

Query: 1047 AEIE-RETSVRIYQYRRPVDSYDIPKTEEASS 1077
             + E RE   RI   +  +    +P+ EE  S
Sbjct: 720  GQEEMREKEERIRDQKEKMQE-RLPEHEERCS 750



 Score = 66.2 bits (160), Expect = 2e-10
 Identities = 49/267 (18%), Positives = 121/267 (45%), Gaps = 24/267 (8%)

Query: 890  VWDQEEERKRQER--------WQKEQDRLLQEKYQREQEKLREE---WQRAK----QEAE 934
            +W+QEE+  +Q+R        W++E+ +  +EK   ++EK+R++   W + K    QE  
Sbjct: 422  MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 481

Query: 935  RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEE 994
            RE    + E+   +      +  +E      E  W +  +  ++E  R  E+++   QEE
Sbjct: 482  REQEDQMWEQEEKMRDQEQKMWDQE------ERMWEQDERLREKE-ERMREQKKMWQQEE 534

Query: 995  VVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETS 1054
             + E++  + Q++   ++E K  ++ +  + +K+++ E E  +   E+ + Q E  RE  
Sbjct: 535  KMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE 594

Query: 1055 VRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTEL--DDYSTNKNGNNKYLDQIGN 1112
             ++++    +   +    E+    +   + +K +   E+  +     +    K  +Q   
Sbjct: 595  EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654

Query: 1113 MTSSQRRSKKEQVPSGAELERQQILQE 1139
            M   + + ++++     + E+ +  +E
Sbjct: 655  MREQEEKMREQEEKMQGQEEKMREQEE 681



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 50/179 (27%), Positives = 92/179 (51%), Gaps = 25/179 (13%)

Query: 890  VWDQEE---------ERKRQERWQKEQDRLLQEKYQREQEKLRE----EWQRAKQEAERE 936
            +W+QEE         ER+++ R ++E  R  +EK Q+++E + E    EWQ+ +   ++E
Sbjct: 381  MWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 440

Query: 937  NSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVV 996
              K  ++E M        +  +E  +   E  W +  K   +E  R  E++  + +E++ 
Sbjct: 441  --KLWEQEKM--QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM- 495

Query: 997  HEDQGKKPQDQLVIERERKWEQ--QLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1053
              DQ +K  DQ     ER WEQ  +L+E++E+ R Q +  +Q+    E+K+  E E++T
Sbjct: 496  -RDQEQKMWDQ----EERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549



 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 70/292 (23%), Positives = 126/292 (43%), Gaps = 40/292 (13%)

Query: 890  VWDQEEERKRQER--WQK-----EQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLD 942
            +W+QEE+ + QE+  W +     EQD  L+EK +R +E+ ++ WQ  ++E  RE  K   
Sbjct: 488  MWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ-KKMWQ--QEEKMREEKK--- 541

Query: 943  EELMVLSSNSMSLTTREPSLATW--EATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ 1000
                          T+E    TW  E    E  +  +RE     EEE  + QEE + E +
Sbjct: 542  --------------TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 587

Query: 1001 GK-KPQDQLVIERERKWEQQLQE--EQEQKRLQAEAEEQKRPAEEQK-RQAEIERETSVR 1056
             K + Q++ + E+E K ++Q ++  EQE+K  + E E++ +  EE    Q E  +E   +
Sbjct: 588  EKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647

Query: 1057 IYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSS 1116
            +++    +   +    E+     + G   K R   E       +    K  +Q   M   
Sbjct: 648  MWEQEEKMREQEEKMREQEEK--MQGQEEKMREQEE-----KMQGQEEKMREQEEKMRGQ 700

Query: 1117 QRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLP 1168
            + +   ++     + E+    +EMR++     D     Q     ++E  S P
Sbjct: 701  EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEP 752



 Score = 64.3 bits (155), Expect = 8e-10
 Identities = 76/339 (22%), Positives = 134/339 (39%), Gaps = 48/339 (14%)

Query: 893  QEEERKRQER----W-QKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMV 947
            +E+E + QE+    W Q+E+ R  +EK  R++E+L   W++ KQ  E+E      EE M 
Sbjct: 306  REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL---WEQEKQMREQEQKMRDQEERM- 361

Query: 948  LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGE-------------EERRQPQEE 994
                   L  +E  +   E  W +  K  + E  R  E             EE+ Q QEE
Sbjct: 362  -WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420

Query: 995  VVHEDQGKKPQDQ-LVIERERKWEQQLQEEQEQKRLQAE-----------------AEEQ 1036
             + E + K+ Q Q L  ++E+ WEQ+  +EQE+K  + E                  +E+
Sbjct: 421  NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 480

Query: 1037 KRPAEEQK-RQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDD 1095
             R  E+Q   Q E  R+   +++     +   D    E+     +   +   +   ++ +
Sbjct: 481  MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEER--MREQKKMWQQEEKMRE 538

Query: 1096 YSTNKNGNNKYLDQIGNMTSSQR---RSKKEQVPSGAELERQQILQEMRKRTPLHNDNSW 1152
                +    K  DQ   M   +R   R KK +       E+++ +QE  ++     +  W
Sbjct: 539  EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMW 598

Query: 1153 IRQRSASVNKEPV-SLPGIMRRGESLDNLDSPRSNSWRQ 1190
             ++      +E +      M   E  D +       W Q
Sbjct: 599  EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQ 637



 Score = 50.1 bits (118), Expect = 1e-05
 Identities = 54/253 (21%), Positives = 99/253 (39%), Gaps = 27/253 (10%)

Query: 768  KEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESL- 826
            +E EE M + ++       +R   K    E K  D    +   E+           E + 
Sbjct: 517  REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 576

Query: 827  --QSSNIESKEINGIHDESNAFESKAS-ESISLKNLKRRSQFFEQGSSDSVVPDLPVPTI 883
              Q   ++ +E      E   +E +   +    K  ++  + +EQ   D +         
Sbjct: 577  REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM--------- 627

Query: 884  SAPSRWVWDQEEERKRQER--WQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYL 941
                  +W+QEE+ + QE   W++E+    QE+  REQ    EE  + ++E  RE  + +
Sbjct: 628  QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ----EEKMQGQEEKMREQEEKM 683

Query: 942  DEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQG 1001
              +   +      +  +E      E  W +  K   +E    G+EE R+ +E +   DQ 
Sbjct: 684  QGQEEKMREQEEKMRGQE------EKMWGQEEKMWGQEEKMWGQEEMREKEERI--RDQK 735

Query: 1002 KKPQDQLVIERER 1014
            +K Q++L    ER
Sbjct: 736  EKMQERLPEHEER 748



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 26/123 (21%), Positives = 61/123 (49%), Gaps = 2/123 (1%)

Query: 380 QNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK-WKDRRKSYTSDLQ-KKKEEREEIEKQAL 437
           Q  +  R E+M++ + Q+ EQ++K +D   K W    + +  D + ++KEER   +K+  
Sbjct: 471 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMW 530

Query: 438 EKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERV 497
           ++ ++  +  K   Q++++ +Q+  +    RM   +  + E +        +   Q E++
Sbjct: 531 QQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 590

Query: 498 EEK 500
            E+
Sbjct: 591 REQ 593



 Score = 35.8 bits (81), Expect = 0.29
 Identities = 27/149 (18%), Positives = 67/149 (44%), Gaps = 12/149 (8%)

Query: 377 EDVQNLRQLRYEEMQKIKSQ---LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIE 433
           E +Q   +  +E+ +K++ Q   ++EQ++K Q    K +++ +      +K +E+ E++ 
Sbjct: 639 EKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMR 698

Query: 434 KQALEKSKRSSKTF--------KEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTM 485
            Q  +   +  K +        +E ++++E + +      + R+   ++   E   PP+ 
Sbjct: 699 GQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSK 758

Query: 486 TVSEASYQSERVEEKGATYPSEIPKEDST 514
            +   S+    VE  G       P+++ T
Sbjct: 759 VLCNMSHTGS-VEPAGGEAGEGSPQDNPT 786



 Score = 35.0 bits (79), Expect = 0.49
 Identities = 30/159 (18%), Positives = 78/159 (49%), Gaps = 10/159 (6%)

Query: 377 EDVQNLRQLRYE--EMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEK 434
           E  + LR+   E  E +K++ Q +EQ Q+ ++ + + +++ +     + +++E   E EK
Sbjct: 287 EQEKELREQEKELREQKKLREQ-EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK 345

Query: 435 QALEKSKRSSKTFKEML-QDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQ 493
           Q  E+ ++     + M  QD   + ++  +  + +M+  ++ ++E +R     + E   +
Sbjct: 346 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEER-----IREREKK 400

Query: 494 SERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQ 532
               EE       ++ K++   + ++E++   + +LP Q
Sbjct: 401 MREEEETMREQEEKMQKQEENMW-EQEEKEWQQQRLPEQ 438



 Score = 34.7 bits (78), Expect = 0.64
 Identities = 25/151 (16%), Positives = 69/151 (45%), Gaps = 12/151 (7%)

Query: 380 QNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEK 439
           Q   Q + E++ + + ++++Q++ W  +   W+  +     D   ++EE+   ++Q +  
Sbjct: 445 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 504

Query: 440 SKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKR-----PPTMTVSEASYQS 494
            +       E L+++E + ++     +++M+  ++ + E K+       T    E   + 
Sbjct: 505 QEERMWEQDERLREKEERMRE-----QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE 559

Query: 495 ERV--EEKGATYPSEIPKEDSTTFAKREDRV 523
           ER+   EK      E+ +E      ++E+++
Sbjct: 560 ERMREREKKMREEEEMMREQEEKMQEQEEKM 590



 Score = 34.3 bits (77), Expect = 0.83
 Identities = 32/168 (19%), Positives = 67/168 (39%), Gaps = 5/168 (2%)

Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447
           EE  + + + +EQ++K  D   K ++  +    + +KK  E EE+ ++  EK +   +  
Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERM--REREKKMREEEEMMREQEEKMQEQEEKM 590

Query: 448 KEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASY--QSERVEEKGATYP 505
           +E  +    Q +K       +M+  ++ + E +    M   E     Q E+++E+     
Sbjct: 591 REQEEKMWEQEEKMQ-EQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649

Query: 506 SEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 553
            +  K        RE     + Q       EE+       +R +  +M
Sbjct: 650 EQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKM 697



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 28/157 (17%), Positives = 73/157 (46%), Gaps = 12/157 (7%)

Query: 383 RQLRYEEMQKIKSQ---LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER--------EE 431
           +Q+R +E QK++ Q   + EQD++ ++   + +++ K +  + + ++EER         E
Sbjct: 345 KQMREQE-QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE 403

Query: 432 IEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEAS 491
            E+   E+ ++  K  + M +  E + Q+  +P ++      + ++E +        +  
Sbjct: 404 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 463

Query: 492 YQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQ 528
            Q E   ++   +  E  +E      ++E+++  + Q
Sbjct: 464 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ 500



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 18/95 (18%), Positives = 53/95 (55%), Gaps = 4/95 (4%)

Query: 388 EEMQKIKSQLKEQD---QKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 444
           EEM + + +L+EQ+   +K ++ + + ++R +     +++++E+    EK+  E+ K   
Sbjct: 234 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELR 293

Query: 445 KTFKEMLQDRESQNQKSTVPSR-RRMYSFDDVLEE 478
           +  KE+ + ++ + Q+  +  +  +M+  ++ + E
Sbjct: 294 EQEKELREQKKLREQEEQMQEQEEKMWEQEEKMRE 328



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 23/173 (13%), Positives = 71/173 (41%)

Query: 328 LRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRY 387
           +R+++    +   R W             R  +K++ +       +   E  + +R+   
Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEE 406

Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447
              ++ +   K+++  W+ +  +W+ +R     +   ++E+ +E E++  E+ ++     
Sbjct: 407 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 466

Query: 448 KEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 500
           +   Q+++   Q+       +M+  ++ + + ++           Q ER+ EK
Sbjct: 467 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK 519



 Score = 32.7 bits (73), Expect = 2.4
 Identities = 19/132 (14%), Positives = 56/132 (42%), Gaps = 1/132 (0%)

Query: 330 KKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEE 389
           +++    E  +++W        +       +K+  E       +   ++ +   + + E+
Sbjct: 537 REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK 596

Query: 390 MQKIKSQLKEQDQK-WQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFK 448
           M + + +++EQ++K W+ +   W+   +    + ++   E+EE  ++  EK     +  +
Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR 656

Query: 449 EMLQDRESQNQK 460
           E  +    Q +K
Sbjct: 657 EQEEKMREQEEK 668



 Score = 31.2 bits (69), Expect = 7.0
 Identities = 20/132 (15%), Positives = 66/132 (50%), Gaps = 9/132 (6%)

Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQ- 435
           E  + +R+ + E+M + + +L EQ+++ ++   K +D+ +      ++ +E+ E + +Q 
Sbjct: 321 EQEEKMRE-QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379

Query: 436 -------ALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVS 488
                   +++ +R  +  K+M ++ E+  ++     ++    ++   +E ++       
Sbjct: 380 KMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 439

Query: 489 EASYQSERVEEK 500
           E  ++ E+++E+
Sbjct: 440 EKLWEQEKMQEQ 451



 Score = 30.8 bits (68), Expect = 9.2
 Identities = 25/116 (21%), Positives = 59/116 (50%), Gaps = 9/116 (7%)

Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447
           E+M + + +L+EQ+ K ++   K + + K     L+++++E  E EK+  E+ K   +  
Sbjct: 255 EKMWRQEERLREQEGKMREQEEKMRRQEKR----LREQEKELREQEKELREQKKLREQ-- 308

Query: 448 KEMLQDRES---QNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 500
           +E +Q++E    + ++       +M+  ++ L E ++       +   Q ER+ E+
Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364


>gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens]
          Length = 436

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 55/214 (25%), Positives = 104/214 (48%), Gaps = 16/214 (7%)

Query: 849  KASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQD 908
            K  E +  +  + R Q  + G  +  V            +    +E+ R+++E+ +++++
Sbjct: 217  KQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEE 276

Query: 909  RLLQEKYQREQEKL---REEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATW 965
            ++L++K Q EQE+    +EE  R ++E  RE  + + E+   +      +  +E  +  W
Sbjct: 277  QMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQM--W 334

Query: 966  EAT---WSEGSKSSDREGTRAGEEERRQPQEEVV--HEDQGKKPQDQLVIERE--RKWEQ 1018
            E     W +  +   +E     +EE+ Q QEE V   E+Q +K ++Q+  + E  RK E+
Sbjct: 335  EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEE 394

Query: 1019 QLQEEQ----EQKRLQAEAEEQKRPAEEQKRQAE 1048
            Q+ E++    EQK    E EEQ    +EQ R+ E
Sbjct: 395  QMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQE 428



 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 69/288 (23%), Positives = 129/288 (44%), Gaps = 19/288 (6%)

Query: 890  VWDQEEERKRQERWQKEQDRLL--QEKYQREQE-KLRE-EWQRAKQEAE-RENSKYLDEE 944
            V +QE + + QE   +EQ+  +  QE   REQE ++RE E Q  +QE + RE    + E+
Sbjct: 138  VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQ 197

Query: 945  LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERR-QPQEEVV--HEDQG 1001
               +      +  +E  +   E    E  +   ++  + GE+E + Q QEE V   E+Q 
Sbjct: 198  EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQM 257

Query: 1002 KKPQDQLVIERERKWEQQLQ-----EEQEQKRLQAEAEEQKRPAEEQKRQAEIE-RETSV 1055
            +K ++Q+  + E+  EQ+ Q     E+ EQ+    E EEQ R  EEQ R+ E + RE   
Sbjct: 258  RKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEE 317

Query: 1056 RIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTS 1115
            ++ +    +   +    E+    +      K +   + +     +    K  +Q+     
Sbjct: 318  QMREQEEQMGKQEEQMWEQKEQMW----EQKEQMWKQEEQMGEQEEQMQKQEEQV-RKQE 372

Query: 1116 SQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1163
             Q R ++EQ+    E  R+Q  Q   ++  +      +R++   + ++
Sbjct: 373  EQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQ 420



 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 68/283 (24%), Positives = 123/283 (43%), Gaps = 23/283 (8%)

Query: 890  VWDQEEERKRQERWQKEQDRLL--QEKYQREQE-KLRE-EWQRAKQEAE-RENSKYLDEE 944
            V +QE + + QE   +EQ+  +  QE   REQE ++RE E Q  +QE + RE    + E+
Sbjct: 110  VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 169

Query: 945  LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGE-EERRQPQEEVV--HEDQG 1001
               +      +  +E  +   E    E       +  + GE EE+ Q QEE +   E+Q 
Sbjct: 170  EGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQM 229

Query: 1002 KKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIE-RETSVRIYQY 1060
            +K ++Q+    E++ + Q QEEQ QK+     EEQ R  EEQ R+ E + RE   ++ + 
Sbjct: 230  RKQEEQM---GEQEEQVQKQEEQVQKQ-----EEQMRKQEEQMREQEEQMREQEEQMLKQ 281

Query: 1061 RRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRS 1120
            +   +  +    +E         R +     E ++    +    +  ++       Q   
Sbjct: 282  KEQTEQEEQTGEQEEQM------REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWE 335

Query: 1121 KKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1163
            +KEQ+    E   +Q  Q   +   +      +R++   + K+
Sbjct: 336  QKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ 378



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 35/169 (20%), Positives = 76/169 (44%), Gaps = 9/169 (5%)

Query: 388 EEMQKIKSQLKEQDQ---KWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 444
           E+MQK + Q+ EQ++   K ++ + + +++ +     +QK++E+  + E+Q  E+ ++  
Sbjct: 213 EQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMR 272

Query: 445 KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATY 504
           +  ++ML+ +E   Q+     +          EE  R     + E   Q    EE+    
Sbjct: 273 EQEEQMLKQKEQTEQEEQTGEQEEQMREQ---EEQMREQEEQMREQEEQMREQEEQMGKQ 329

Query: 505 PSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 553
             ++ ++    + ++E     E Q+  Q   EEQ       +R +  QM
Sbjct: 330 EEQMWEQKEQMWEQKEQMWKQEEQMGEQ---EEQMQKQEEQVRKQEEQM 375



 Score = 39.3 bits (90), Expect = 0.026
 Identities = 35/169 (20%), Positives = 78/169 (46%), Gaps = 16/169 (9%)

Query: 388 EEMQKIKSQLKEQD---QKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 444
           E+M+K + Q+ EQ+   QK ++ + K +++ +     +++++E+  E E+Q L++ +++ 
Sbjct: 227 EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTE 286

Query: 445 KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATY 504
           +  +E   ++E Q ++     R +        EE  R     + E   Q  + EE+    
Sbjct: 287 Q--EEQTGEQEEQMREQEEQMREQ--------EEQMREQEEQMREQEEQMGKQEEQMWEQ 336

Query: 505 PSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 553
             ++ ++    + + E     E Q+  Q   EEQ       +R +  QM
Sbjct: 337 KEQMWEQKEQMWKQEEQMGEQEEQMQKQ---EEQVRKQEEQMRKQEEQM 382



 Score = 38.5 bits (88), Expect = 0.044
 Identities = 53/256 (20%), Positives = 106/256 (41%), Gaps = 21/256 (8%)

Query: 911  LQEKYQREQEKLREEWQRAKQEAE-RENSKYLDEELMVLSSNSMSLTTREPSLATWEATW 969
            L+ K + ++  L +E Q  +QE + RE    + E+   +      +  +E  +   E   
Sbjct: 37   LKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 96

Query: 970  SEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQDQLVIERERKWEQQLQEEQEQKR 1028
             E      +EG    +E + + QE  V E +G+ + Q+  V E+E +  +Q  + +EQ+ 
Sbjct: 97   RE------QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 150

Query: 1029 LQAEAEEQKRPAEEQKRQAEIE-RETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKS 1087
               E E Q R  E Q R+ E + RE   ++ +    V      + +E   G   G   + 
Sbjct: 151  QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV------REQEGQMGEQEGQMGEQ 204

Query: 1088 RSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLH 1147
                  +     +    K  +Q+G     Q R ++EQ+    E  ++Q  Q  ++   + 
Sbjct: 205  E-----EQMGEQEEQMQKQEEQMGEQ-EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR 258

Query: 1148 NDNSWIRQRSASVNKE 1163
                 +R++   + ++
Sbjct: 259  KQEEQMREQEEQMREQ 274



 Score = 35.8 bits (81), Expect = 0.29
 Identities = 40/144 (27%), Positives = 67/144 (46%), Gaps = 15/144 (10%)

Query: 928  RAKQEAERENSKYLDEELMVLSSNSMSLTTR----EPSLATWEATWSEGSKSSDREGTRA 983
            R   E  +E +  L EEL ++ +    +       +  L T +    +  +  ++EG   
Sbjct: 3    RITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVR 62

Query: 984  GEEERRQPQEEVVHEDQGK-KPQDQLVIERE---RKWEQQLQEEQEQKRLQA----EAEE 1035
             +E + + QE  V E +G+ + Q+  V E+E   R+ E Q++E++ Q R Q     E E 
Sbjct: 63   EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 122

Query: 1036 QKRPAEEQKRQAE---IERETSVR 1056
            Q R  E Q R+ E    E+E  VR
Sbjct: 123  QVREQEGQVREQEGQVREQEGQVR 146



 Score = 35.4 bits (80), Expect = 0.37
 Identities = 42/159 (26%), Positives = 74/159 (46%), Gaps = 12/159 (7%)

Query: 909  RLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEAT 968
            R+  E+ + +  +L+EE Q  + E + E   ++ E    L ++ + L             
Sbjct: 3    RITNEELKEKNAELQEELQLVETE-KSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQV 61

Query: 969  WSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQDQLVIERE---RKWEQQLQEEQ 1024
              +  +  ++EG    +E + + QE  V E +G+ + Q+  V E+E   R+ E Q++E++
Sbjct: 62   REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 121

Query: 1025 EQKRLQA----EAEEQKRPAEEQKRQAE---IERETSVR 1056
             Q R Q     E E Q R  E Q R+ E    E+E  VR
Sbjct: 122  GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 160



 Score = 35.0 bits (79), Expect = 0.49
 Identities = 19/96 (19%), Positives = 51/96 (53%), Gaps = 3/96 (3%)

Query: 365 ENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQL-KEQDQKWQDDLAKWKDRRKSYTSDLQ 423
           E   +   +   E  + +R+ + E+M++ + Q+ K+++Q W+     W+ + + +  + +
Sbjct: 295 EEQMREQEEQMREQEEQMRE-QEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE-E 352

Query: 424 KKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQ 459
           +  E+ E+++KQ  +  K+  +  K+  Q R+ + Q
Sbjct: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQ 388



 Score = 34.3 bits (77), Expect = 0.83
 Identities = 31/180 (17%), Positives = 80/180 (44%), Gaps = 17/180 (9%)

Query: 388 EEMQKIKSQLKEQDQ---KWQDDLAKWKDRRKSYTSDLQKKKEERE------EIEKQALE 438
           E++QK + Q+++Q++   K ++ + + +++ +     + K+KE+ E      E E+Q  E
Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300

Query: 439 KSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTM-----TVSEASYQ 493
           + ++  +  ++M +  E   ++     ++    ++   +  ++   M      + E   Q
Sbjct: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360

Query: 494 SERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 553
            ++ EE+      ++ K++     + E     E Q+  Q   +EQ       +R +  QM
Sbjct: 361 MQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQ---KEQMGEQKEQMREQEEQM 417



 Score = 34.3 bits (77), Expect = 0.83
 Identities = 29/178 (16%), Positives = 82/178 (46%), Gaps = 12/178 (6%)

Query: 380 QNLRQLRYEEMQKIKSQLKEQDQKWQDD-LAKWKDRRKSYTSDLQKKKEEREEIEKQALE 438
           + +R+   +  ++ +  LK+++Q  Q++   + +++ +     +++++E+  E E+Q  E
Sbjct: 262 EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321

Query: 439 KSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVL---EEGKRPPTMTVSEASYQSE 495
           + ++  K  ++M + +E   ++     + +M+  ++ +   EE  +     V +   Q  
Sbjct: 322 QEEQMGKQEEQMWEQKEQMWEQ-----KEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMR 376

Query: 496 RVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 553
           + EE+      ++ K++     ++E     + Q+  Q   EEQ       +R +   M
Sbjct: 377 KQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQ---EEQMGEQKEQMRKQEEHM 431



 Score = 32.7 bits (73), Expect = 2.4
 Identities = 15/76 (19%), Positives = 44/76 (57%), Gaps = 3/76 (3%)

Query: 388 EEMQKIKSQLKEQDQ---KWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 444
           E+MQK + Q+++Q++   K ++ + K +++ +     + ++KE+  E ++Q  E+ ++  
Sbjct: 359 EQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMG 418

Query: 445 KTFKEMLQDRESQNQK 460
           +  ++M +  E   ++
Sbjct: 419 EQKEQMRKQEEHMGEQ 434



 Score = 30.8 bits (68), Expect = 9.2
 Identities = 36/174 (20%), Positives = 75/174 (43%), Gaps = 16/174 (9%)

Query: 384 QLRYEEMQ--KIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSK 441
           Q+R +E Q  + + Q++EQ+ + ++   +  ++        ++  E+ E+++KQ  +  +
Sbjct: 165 QVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGE 224

Query: 442 RSSKTFK--EMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEE 499
           +  +  K  E + ++E Q QK     +++        EE  R     + E   Q    EE
Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQKQ--------EEQMRKQEEQMREQEEQMREQEE 276

Query: 500 KGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 553
           +      +  +E+ T   + + R   E Q+  Q   EEQ       +R +  QM
Sbjct: 277 QMLKQKEQTEQEEQTGEQEEQMREQEE-QMREQ---EEQMREQEEQMREQEEQM 326



 Score = 30.8 bits (68), Expect = 9.2
 Identities = 16/75 (21%), Positives = 43/75 (57%), Gaps = 3/75 (4%)

Query: 384 QLRYEEMQKIKSQLKEQDQ---KWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS 440
           Q + E+++K + Q+++Q++   K ++ + K +++       + ++KE+  E E+Q  E+ 
Sbjct: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421

Query: 441 KRSSKTFKEMLQDRE 455
           ++  K  + M + +E
Sbjct: 422 EQMRKQEEHMGEQKE 436


>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
          Length = 793

 Score = 69.3 bits (168), Expect = 2e-11
 Identities = 80/340 (23%), Positives = 142/340 (41%), Gaps = 39/340 (11%)

Query: 734  VASVEAGSPAEFSQLQVDDEIIAINN-TKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGK 792
            V   EA +    +Q++ DDE   +    +      K  +EA+ + +E    + D      
Sbjct: 74   VPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDA----S 129

Query: 793  AGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNI-ESKEINGIHD-ESNAFESKA 850
               P  +  + T+    +EK        +  E  ++  + +S + N   D E N  E K 
Sbjct: 130  LSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKE 189

Query: 851  SESISLKNLKRRS-----------QFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKR 899
             E    +  KR S           +   +   ++VV  L    IS+         EE K+
Sbjct: 190  KEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISS---------EEPKQ 240

Query: 900  QERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAE-------RENSKYLDEELMVLSSNS 952
            +E  ++  D +   +   E++K R E +RA+ EAE        ++ K  DE   + +   
Sbjct: 241  EEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEK 300

Query: 953  MSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIER 1012
             +   RE   A       E  K +  E  R  EEE+R  +E    +++ K+  +    ER
Sbjct: 301  AAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE----ER 356

Query: 1013 ERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052
            +R  E++ +  +E++R +AE EE+K   EEQKR  ++E +
Sbjct: 357  QRIKEEEKRAAEERQRARAE-EEEKAKVEEQKRNKQLEEK 395



 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 147/755 (19%), Positives = 285/755 (37%), Gaps = 99/755 (13%)

Query: 406  DDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPS 465
            DD  + ++ R+      QK++E R E E+ A +   R+    +E  ++R  + ++  +  
Sbjct: 2    DDFERRRELRR------QKREEMRLEAERIAYQ---RNDDDEEEAARERRRRARQERLRQ 52

Query: 466  RRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTT 525
            ++   S   V ++ +     +V +        E K  T  +++  +D   F +R  R   
Sbjct: 53   KQEEESLGQVTDQVEVNAQNSVPDE-------EAKTTTTNTQVEGDDEAAFLERLARR-- 103

Query: 526  EIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGS 585
                      EE+    L     R  + + T   ASL    R+       +  T +   S
Sbjct: 104  ----------EERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKS 153

Query: 586  QTRG-------ISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSS 638
            ++R          ++ +SY  +D W+   D E+ K+            P    +      
Sbjct: 154  ESRQERYEIEETETVTKSYQKND-WR---DAEENKKEDKEKEEEEEEKPKRGSIG----- 204

Query: 639  QKEVAATEEDVTRLPSPTSPFSSLSQDQAATS--KATLSSTSGLDLMS--ESGEGEISPQ 694
            + +V    E+ T      +   SL   Q ++   K       G D +S  E  E E   +
Sbjct: 205  ENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKER 264

Query: 695  REVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASV------------EAGSP 742
             E  R++ +  +      +   K  D    I+ +                     E    
Sbjct: 265  AEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRA 324

Query: 743  AEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWID 802
            AE  Q   ++E  A    +    + K   E   + +E      + R+  +A   E   ++
Sbjct: 325  AEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVE 384

Query: 803  ATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRR 862
                    E+  +    T          IE K +N    E  A E K   ++    LK++
Sbjct: 385  EQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVN----EKKAQEDKLQTAV----LKKQ 436

Query: 863  SQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKL 922
             +  E+G+            + A    + + +   K++E    + +++ ++K  +E+ K 
Sbjct: 437  GE--EKGTK-----------VQAKREKLQEDKPTFKKEEI---KDEKIKKDKEPKEEVKS 480

Query: 923  REEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTR 982
              + ++   E + +N +++  +L   + N+ S      S+ T EA   EG+   +  G R
Sbjct: 481  FMDRKKGFTEVKSQNGEFMTHKLKH-TENTFSRPGGRASVDTKEA---EGAPQVEA-GKR 535

Query: 983  AGEEERRQPQEEVVHEDQGKKPQDQLVIERE-----RKWEQQLQEEQEQKRLQAEAEEQK 1037
              E  RR+ + E    ++ K+ Q +  +E E     R+  +++ EE+EQ+R Q EA+ + 
Sbjct: 536  LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKL 595

Query: 1038 RPAEEQKR-QAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLP-GDRNKSRSTTELDD 1095
            R  EE++R + EIER  +    + R+ +    +   ++    F P G   K     E  +
Sbjct: 596  REEEEKRRLKEEIERRRA-EAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLN 654

Query: 1096 YSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAE 1130
             S  K+   K   Q   +  S+  S+ EQ  S  E
Sbjct: 655  KSVQKSSGVKSTHQAAIV--SKIDSRLEQYTSAIE 687



 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 68/305 (22%), Positives = 122/305 (40%), Gaps = 52/305 (17%)

Query: 892  DQEEERKRQERWQKEQDRLLQEK--YQR----EQEKLREEWQRAKQE--AERENSKYLDE 943
            D  E R+   R ++E+ RL  E+  YQR    E+E  RE  +RA+QE   +++  + L +
Sbjct: 2    DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61

Query: 944  ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003
                +  N+ +    E +  T   T  EG   +      A  EERRQ           K+
Sbjct: 62   VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQ-----------KR 110

Query: 1004 PQDQLVIERERKWEQQLQEEQ---EQKRLQAEAEEQKRPAEEQKRQAEIER------ETS 1054
             Q+ L  ER+++++  + +       +R+Q +  E +   +E+K ++  ER      ET 
Sbjct: 111  LQEAL--ERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETV 168

Query: 1055 VRIYQYRRPVDS-----YDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQ 1109
             + YQ     D+      D  K EE       G   +++    +++ +T        +  
Sbjct: 169  TKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSL 228

Query: 1110 IGNMTSSQRRSKKEQVPSG-----------------AELERQQILQEMRKRTPLHNDNSW 1152
                 SS+   ++E+   G                 AE ER ++  E R+R     D   
Sbjct: 229  KNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKI 288

Query: 1153 IRQRS 1157
              +R+
Sbjct: 289  ADERA 293



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 57/262 (21%), Positives = 111/262 (42%), Gaps = 22/262 (8%)

Query: 895  EERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMS 954
            +ER R E  +K   +  + +   E+E++REE +RA +E +R     + EE    +     
Sbjct: 290  DERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQR-----IKEEEKRAAEERQR 344

Query: 955  LTTREPSLATWEATWSEGSKSSDREGTRAGEEE----------RRQPQEEVVHEDQGKKP 1004
            +   E   A       E  K +  E  RA  EE          R +  EE  H  Q  K 
Sbjct: 345  IKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKI 404

Query: 1005 QDQLVIER-ERKW--EQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYR 1061
            + + V ++ E KW  E++ QE++ Q  +  +  E+K    + KR+   E + + +  + +
Sbjct: 405  KGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIK 464

Query: 1062 RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSK 1121
                  D    EE  S F+   +  +   ++  ++ T+K    K+ +   +    +    
Sbjct: 465  DEKIKKDKEPKEEVKS-FMDRKKGFTEVKSQNGEFMTHK---LKHTENTFSRPGGRASVD 520

Query: 1122 KEQVPSGAELERQQILQEMRKR 1143
             ++     ++E  + L+E+R+R
Sbjct: 521  TKEAEGAPQVEAGKRLEELRRR 542



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 63/282 (22%), Positives = 128/282 (45%), Gaps = 18/282 (6%)

Query: 893  QEEERKRQERWQ-KEQDRLLQEKYQR---EQEKLREEWQRAKQEA-----ERENSKYLDE 943
            +EE+R  +ER + KE+++   E+ QR   E+++  EE QR K+E      ER+ ++  +E
Sbjct: 319  EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEE 378

Query: 944  ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDR-EGTRAGEEERRQPQ-EEVVHEDQG 1001
            E   +     +    E   A  E T  +G K   + EG    E++ ++ + +  V + QG
Sbjct: 379  EKAKVEEQKRNKQLEEKKHAMQE-TKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQG 437

Query: 1002 KKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYR 1061
            ++   ++  +RE+  E +   ++E+ +   + ++ K P EE K   +  ++    +    
Sbjct: 438  EEKGTKVQAKREKLQEDKPTFKKEEIK-DEKIKKDKEPKEEVKSFMD-RKKGFTEVKSQN 495

Query: 1062 RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNN-KYLDQIGNMTSSQRRS 1120
                ++ +  TE   S   PG R  S  T E +     + G   + L +    T S+   
Sbjct: 496  GEFMTHKLKHTENTFS--RPGGR-ASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFE 552

Query: 1121 KKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNK 1162
            K +Q    A LE +++ ++  +R  +  +    R++  +  K
Sbjct: 553  KLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRK 594



 Score = 35.0 bits (79), Expect = 0.49
 Identities = 45/203 (22%), Positives = 83/203 (40%), Gaps = 31/203 (15%)

Query: 329 RKKKPDKHEDNRRSWASPVYTEADGTF-SRLFQKIYGENGSKSMSDVSAEDVQNLRQLRY 387
           R++K  +    R+    P  T+A  +  SR  Q    EN +        E+    RQ RY
Sbjct: 106 RRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET-----TEKEEKSESRQERY 160

Query: 388 --EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS- 444
             EE + +    ++ D         W+D  ++   D  K+KEE EE      EK KR S 
Sbjct: 161 EIEETETVTKSYQKND---------WRDAEENKKED--KEKEEEEE------EKPKRGSI 203

Query: 445 --KTFKEMLQDRESQNQKSTVP---SRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEE 499
                + M++++ +++Q+ TV       ++ S +   EE +   +  +S      E  +E
Sbjct: 204 GENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKE 263

Query: 500 KGATYPSEIPKEDSTTFAKREDR 522
           +     + +  E+       +D+
Sbjct: 264 RAEAERARLEAEERERIKAEQDK 286



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 27/123 (21%), Positives = 59/123 (47%), Gaps = 12/123 (9%)

Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447
           EE +K+K + +E   + ++   K ++RRK    + Q++K+E  + + +  E+ +R     
Sbjct: 549 EEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRR----L 604

Query: 448 KEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSE 507
           KE ++ R ++       + +R    +D L + K+P      + S  S ++EE+       
Sbjct: 605 KEEIERRRAE------AAEKRQKMPEDGLSDDKKPFKCFTPKGS--SLKIEERAEFLNKS 656

Query: 508 IPK 510
           + K
Sbjct: 657 VQK 659



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 40/202 (19%), Positives = 84/202 (41%), Gaps = 17/202 (8%)

Query: 364 GENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQ 423
           GEN  + M +    + Q    +   +  +I S+  +Q+++ +    +     K    D +
Sbjct: 204 GENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKE 263

Query: 424 KKKEEREEIEKQALE--KSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKR 481
           + + ER  +E +  E  K+++  K   E  +    +   +    RR     + + EE KR
Sbjct: 264 RAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKR 323

Query: 482 PPTMTVSEASYQSERV--EEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQ----SPV 535
                   A+ + +R+  EEK A    +  KE+    A+   R+  E +  ++    +  
Sbjct: 324 --------AAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARA 375

Query: 536 EEQSPASLSSLRSRSTQMESTR 557
           EE+  A +   + R+ Q+E  +
Sbjct: 376 EEEEKAKVEE-QKRNKQLEEKK 396



 Score = 32.7 bits (73), Expect = 2.4
 Identities = 39/168 (23%), Positives = 71/168 (42%), Gaps = 30/168 (17%)

Query: 380 QNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER------EEIE 433
           + LR+ + EEM+    ++  Q     ++ A  + RR++    L++K+EE       +++E
Sbjct: 8   RELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVE 67

Query: 434 KQAL-----EKSKRSS----------KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEE 478
             A      E++K ++            F E L  RE + QK    +  R   FD     
Sbjct: 68  VNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFD----- 122

Query: 479 GKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTE 526
               PT+T +  S  S R++   A   +   +E S +  +R +   TE
Sbjct: 123 ----PTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETE 166



 Score = 32.3 bits (72), Expect = 3.2
 Identities = 37/171 (21%), Positives = 73/171 (42%), Gaps = 29/171 (16%)

Query: 384 QLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRS 443
           +L  EE ++IK+   EQD+K  D+ A+ +   K+         +ERE  E +  E+ +  
Sbjct: 271 RLEAEERERIKA---EQDKKIADERARIEAEEKAAA-------QERERREAEERERMREE 320

Query: 444 SKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGAT 503
            K   E  Q R  + +K     R+R      + EE KR        A+ + +R++E+   
Sbjct: 321 EKRAAEERQ-RIKEEEKRAAEERQR------IKEEEKR--------AAEERQRIKEE--- 362

Query: 504 YPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQME 554
                 +E     A+ E++   E Q  ++   E++     + ++    + +
Sbjct: 363 -EKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQK 412



 Score = 32.3 bits (72), Expect = 3.2
 Identities = 49/279 (17%), Positives = 113/279 (40%), Gaps = 24/279 (8%)

Query: 379 VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALE 438
           ++ LR+ R E   +   +LK++ Q+   +L            +L+KK+EER ++ ++  E
Sbjct: 536 LEELRRRRGETESEEFEKLKQKQQEAALEL-----------EELKKKREERRKVLEEE-E 583

Query: 439 KSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVE 498
           + ++  +  +++ ++ E +  K  +  RR      +  E+ ++ P   +S+     +   
Sbjct: 584 QRRKQEEADRKLREEEEKRRLKEEIERRRA-----EAAEKRQKMPEDGLSDDKKPFKCFT 638

Query: 499 EKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRV 558
            KG++   E   E      ++   V +  Q    S ++ +     S++    +   +   
Sbjct: 639 PKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPA 698

Query: 559 SASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVED-IKRTPN 617
           ++ LP        ++ +       F S T   +  P   T       +  + + + +TP+
Sbjct: 699 ASDLPVPAEGVRNIK-SMWEKGNVFSSPT--AAGTPNKETAGLKVGVSSRINEWLTKTPD 755

Query: 618 NVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPT 656
                 +P+P  S L     S K     ++ V ++ SPT
Sbjct: 756 ---GNKSPAPKPSDLRPGDVSSKRNLWEKQSVDKVTSPT 791


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
            protein 6 [Homo sapiens]
          Length = 724

 Score = 67.4 bits (163), Expect = 9e-11
 Identities = 48/192 (25%), Positives = 96/192 (50%), Gaps = 14/192 (7%)

Query: 890  VWDQEEE-RKRQERW--------QKEQDRLLQEKYQREQEKLREEWQRAKQEAE---REN 937
            +W QEE+ R+++E W        Q+E+ R  +EK  R++EK+ ++ ++ +++ E   R+ 
Sbjct: 525  MWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQE 584

Query: 938  SKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVH 997
             K  ++E  +           E +    E    +  K  ++E     +EE+ + QEE + 
Sbjct: 585  EKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR 644

Query: 998  EDQGK-KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQ-KRQAEIERETSV 1055
            E + K + Q++ + E+E   ++Q ++  EQ+    E EE+ +  EE+ +RQ E   E  V
Sbjct: 645  EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 704

Query: 1056 RIYQYRRPVDSY 1067
            R+ Q    +  +
Sbjct: 705  RLRQQEEKMQEH 716



 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 67/322 (20%), Positives = 131/322 (40%), Gaps = 47/322 (14%)

Query: 890  VWDQEEERKRQER--WQKEQD-RLL------QEKYQREQEKLREEWQRAKQEAERENSKY 940
            +W++EE+ +RQE   W+KE+  R L      QEK + ++EK +EE      E  RE  K 
Sbjct: 419  MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE------EKIREQEKR 472

Query: 941  LDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ 1000
             ++E  +           E      E  W +  K  ++E  R  EEE+RQ QEE+     
Sbjct: 473  QEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIR--EEEKRQEQEEMWR--- 527

Query: 1001 GKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQY 1060
                Q++ + E+E  W Q+ +  +++++++ + E+  R  E+   Q E  RE   ++++ 
Sbjct: 528  ----QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ 583

Query: 1061 RRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNG--NNKYLDQIGNMTSSQR 1118
               +   +    E+           K R   E+      K G    K  +Q   M   + 
Sbjct: 584  EEKIREQEEKIREQ---------EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 634

Query: 1119 RSKKEQVPSGAE----LERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRG 1174
            + ++++     +     E+++ ++E  +      +  W ++      +E +         
Sbjct: 635  KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ-------- 686

Query: 1175 ESLDNLDSPRSNSWRQPPWLNQ 1196
            E  + +       W Q   L Q
Sbjct: 687  EQEEKMRRQEEKMWEQEVRLRQ 708



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 57/247 (23%), Positives = 122/247 (49%), Gaps = 29/247 (11%)

Query: 832  ESKEING-IHDESNAFESKASE-SISLKNLKRRSQFFE--------QGSSDSVVPDLPVP 881
            E KE N  + ++    ES+ SE  +++K LKR+ +  +        Q  +D +  +L   
Sbjct: 279  ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 338

Query: 882  TISAPSRW----VWDQEEERKRQERW-QKEQDRLLQEKYQREQEKLREEWQRAKQEAE-- 934
            +    ++     +W++  +++ ++ W Q+E+ +  +EK Q ++EK+RE+ ++ +++ E  
Sbjct: 339  SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 398

Query: 935  -RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE 993
             R+     ++E  +     M     E      E  W +  K  + E  +  E+E+ + QE
Sbjct: 399  RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE-EKMHEQEKIREQE 457

Query: 994  EVVHEDQGKKPQDQLVIERERKW--EQQLQEEQEQKRLQAE--------AEEQKRPAEEQ 1043
            E   E++  + Q++   +  + W  E++++E++E+ R Q E          EQ++  EE+
Sbjct: 458  EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEE 517

Query: 1044 KRQAEIE 1050
            KRQ + E
Sbjct: 518  KRQEQEE 524



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 42/170 (24%), Positives = 87/170 (51%), Gaps = 8/170 (4%)

Query: 890  VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAE--RENSKYLDEELMV 947
            +W QEE+   QE   +EQ+    EK  R++EK+RE+ ++ +++ E  RE  +   E+   
Sbjct: 559  MWRQEEKMHDQEEKIREQE----EKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEK 614

Query: 948  LSSNSMSLTTREPSLATWEATWS-EGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK-PQ 1005
            +      +  +E  +   E     +  K  ++E     +EE+ + QEE++ E + K   Q
Sbjct: 615  MGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 674

Query: 1006 DQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSV 1055
            ++ + E+E K ++Q ++ + Q+    E E + R  EE+ ++ +   E ++
Sbjct: 675  EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 53/267 (19%), Positives = 119/267 (44%), Gaps = 21/267 (7%)

Query: 910  LLQEKYQREQEKLREEWQR--AKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEA 967
            L Q++ Q E + L +E Q   AK +A+ E ++  +    +       +  +E  +  WE 
Sbjct: 319  LPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR---LNQQQEEKMWRQEEKIQEWEE 375

Query: 968  TWSEGS-KSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQDQLVIERERK--------WE 1017
               E   K  ++E     +EE+ + QEE++ E + K + Q++++ E+E K        WE
Sbjct: 376  KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 435

Query: 1018 QQLQ----EEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTE 1073
            ++ +    EE+  ++ +   +E+KR  EE+ R+ E  +E   ++++    +   +    E
Sbjct: 436  KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 495

Query: 1074 EASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELER 1133
            +    +   ++   +     ++    +    +  ++I       R  +KE++    E  R
Sbjct: 496  QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR--QKEKIHEQEEKIR 553

Query: 1134 QQILQEMRKRTPLHNDNSWIRQRSASV 1160
            +Q  +  R+   +H+    IR++   V
Sbjct: 554  KQEEKMWRQEEKMHDQEEKIREQEEKV 580



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 34/206 (16%), Positives = 89/206 (43%), Gaps = 16/206 (7%)

Query: 329 RKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYE 388
           +++K  + E+  + W   +  + +    +  +    E   +   ++  E  + +R  R E
Sbjct: 359 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR--RQE 416

Query: 389 EM--QKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKT 446
           EM  +K +   ++++  W+ +    +   K +  +  +++EE+ + E++  E+ KR  + 
Sbjct: 417 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 476

Query: 447 FKEMLQDRESQNQKSTVPSR--------RRMYSFDDVLEEGKRPPTMTVSEASYQSERVE 498
            K   Q+ + + Q+  +  +         +++  + + EE KR       E   Q E++ 
Sbjct: 477 AKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKR---QEQEEMWRQEEKIR 533

Query: 499 EKGATY-PSEIPKEDSTTFAKREDRV 523
           E+   +   E   E      K+E+++
Sbjct: 534 EQEEIWRQKEKIHEQEEKIRKQEEKM 559



 Score = 32.3 bits (72), Expect = 3.2
 Identities = 19/91 (20%), Positives = 48/91 (52%), Gaps = 2/91 (2%)

Query: 380 QNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEK 439
           + + Q + E+M + + ++ EQ++K Q+   K + + +      +K +E+ E+I +Q    
Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 664

Query: 440 SKRSSKTF--KEMLQDRESQNQKSTVPSRRR 468
            ++  K +  +E + ++E + Q+     RR+
Sbjct: 665 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 695



 Score = 31.2 bits (69), Expect = 7.0
 Identities = 26/139 (18%), Positives = 66/139 (47%), Gaps = 6/139 (4%)

Query: 388 EEMQKIKSQLKEQDQKWQDDLAK-WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKT 446
           EE+ + K ++ EQ++K +    K W+   K +  + +K +E+ E++ +Q  EK +   + 
Sbjct: 536 EEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE-EKIREQEEKVWRQE-EKIREQEEK 593

Query: 447 FKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERV--EEKGATY 504
            +E  +++  + ++ T     +M   ++ + E +        +   Q E++  +EK    
Sbjct: 594 IREQ-EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIRE 652

Query: 505 PSEIPKEDSTTFAKREDRV 523
             E  +E      ++E+++
Sbjct: 653 QEEKIREQEEMMQEQEEKM 671


>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
            sapiens]
          Length = 668

 Score = 67.0 bits (162), Expect = 1e-10
 Identities = 52/176 (29%), Positives = 86/176 (48%), Gaps = 18/176 (10%)

Query: 892  DQEEERKRQER--WQKEQDRLLQEKYQREQEKLREEWQRAKQEAE-RENSKYLDEELMVL 948
            +QEE+ + QE+  W+       QE+   EQEK+REE +R +QE   R+  K  ++E +  
Sbjct: 427  EQEEKIREQEKKMWR-------QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479

Query: 949  SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQL 1008
                M    +E      E  W +  K  D+E     +EE+   QEE + E      Q++ 
Sbjct: 480  QKEKMH--EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE------QEEK 531

Query: 1009 VIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPV 1064
            + E+E K  +Q +  QEQ+    E EE+ +  E+ +RQ E  RE   +I + +  +
Sbjct: 532  IREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 51/182 (28%), Positives = 95/182 (52%), Gaps = 15/182 (8%)

Query: 890  VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQ-EAERENSKYLDEELMVL 948
            +W QEE+   QE+ ++E+ R  QE+  R++EK+RE+ +  +Q E   E  K   +E  V 
Sbjct: 439  MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVW 498

Query: 949  SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHE------DQGK 1002
                      E      E  W +  K  ++E     +EE+ + QEE++ E      +Q +
Sbjct: 499  RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEE 558

Query: 1003 KPQDQLVIERERKWEQQLQEEQEQKRLQAE---AEEQKRPAEEQK--RQAEIERETSVRI 1057
            K Q+Q   E+ R+ E++++E++E+ R Q E    +E+K   +E+K   Q E+ +E   ++
Sbjct: 559  KMQEQ---EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKM 615

Query: 1058 YQ 1059
            ++
Sbjct: 616  WE 617



 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 45/184 (24%), Positives = 94/184 (51%), Gaps = 6/184 (3%)

Query: 890  VWDQEEERKRQERWQKEQDRLL--QEKYQREQEKLREEWQR--AKQEAERENSKYLDEEL 945
            +W Q+E+   QE+ +K+++++   +EK   ++EK+RE+ ++   ++E  RE  + + E+ 
Sbjct: 477  IWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQE 536

Query: 946  MVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KP 1004
              +      +  +E  +   E    E  K   +E     +EE+ + Q+E + E + K   
Sbjct: 537  EKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWE 596

Query: 1005 QDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQ-KRQAEIERETSVRIYQYRRP 1063
            Q++ + E+E   ++Q ++  EQ+    E EE+ +  EE+ +RQ E   E  VR+ Q    
Sbjct: 597  QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 656

Query: 1064 VDSY 1067
            +  +
Sbjct: 657  MQEH 660



 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 57/247 (23%), Positives = 120/247 (48%), Gaps = 29/247 (11%)

Query: 832  ESKEING-IHDESNAFESKASE-SISLKNLKRRSQFFE--------QGSSDSVVPDLPVP 881
            E KE N  + ++    ES+ SE  +++K LKR+ +  +        Q  +D +  +L   
Sbjct: 218  ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277

Query: 882  TISAPSRW----VWDQEEERKRQERW-QKEQDRLLQEKYQREQEKLREEWQRAKQEAE-- 934
            +    ++     +W++  +++ ++ W Q+E+ +  +EK Q ++EK+RE+ ++ +++ E  
Sbjct: 278  SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337

Query: 935  -RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE 993
             R+     ++E  +     M     E      E  W +  K  + E  +  E+E+ + QE
Sbjct: 338  RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE-EKMHEQEKIREQE 396

Query: 994  EVVHEDQGKKPQDQLVIERERKWEQQLQ-EEQEQK---------RLQAEAEEQKRPAEEQ 1043
            E   E++  + Q++   +  + W Q+ +  EQE+K         R + +  EQ++  EE+
Sbjct: 397  EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 456

Query: 1044 KRQAEIE 1050
            KRQ + E
Sbjct: 457  KRQEQEE 463



 Score = 62.0 bits (149), Expect = 4e-09
 Identities = 42/164 (25%), Positives = 87/164 (53%), Gaps = 6/164 (3%)

Query: 890  VWDQEEE-RKRQERWQKEQDRLLQEKYQREQEKL--REEWQRAKQEAERENSKYLDEELM 946
            +W QEE+ R+++E W++++    QEK ++++EK+  +EE    ++E  RE  + +  +  
Sbjct: 464  MWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEE 523

Query: 947  VLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQ 1005
             +      +  +E  +   E    E  +    +  +  E+E+ + QEE + E + K + Q
Sbjct: 524  KIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQ 583

Query: 1006 DQLVIERERK-WEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAE 1048
             + + E+E K WEQ+ ++ +EQ+ +  E EE+    EE+  + E
Sbjct: 584  KEKIREQEEKIWEQE-EKIREQEEMMQEQEEKMWEQEEKMCEQE 626



 Score = 59.7 bits (143), Expect = 2e-08
 Identities = 41/172 (23%), Positives = 87/172 (50%), Gaps = 6/172 (3%)

Query: 890  VWDQEEERKRQERWQKEQDRLL---QEKYQREQEKLREEWQRAKQEAE--RENSKYLDEE 944
            VW QEE+   QE   +EQ+  +   +EK + ++EK+RE+ ++ +++ E  +E  + + E+
Sbjct: 497  VWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ 556

Query: 945  LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK- 1003
               +          E      E    +  K  ++E     +EE+ + QEE++ E + K  
Sbjct: 557  EEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMW 616

Query: 1004 PQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSV 1055
             Q++ + E+E K ++Q ++ + Q+    E E + R  EE+ ++ +   E ++
Sbjct: 617  EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668



 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 66/283 (23%), Positives = 126/283 (44%), Gaps = 21/283 (7%)

Query: 893  QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNS 952
            QE+E K +E  Q+E+ R  +EK +R++E +   W++ ++   +E   +  EE M      
Sbjct: 317  QEQEEKIRE--QEEKIREQEEKMRRQEEMM---WEKEEKMRRQEEMMWEKEEKMRRLEEM 371

Query: 953  MSLTTREPSLATWEATWSEGSKSSDREGTRAGEE-----ERRQPQEEVVHEDQGK-KPQD 1006
            M    +E  +   E    E  K  ++E  R  EE     E+RQ QE  +   + K + Q+
Sbjct: 372  M--WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 429

Query: 1007 QLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDS 1066
            + + E+E+K  +Q ++  EQ++++   EE+++  EE  RQ E  RE      Q  +  + 
Sbjct: 430  EKIREQEKKMWRQEEKIHEQEKIR--EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ 487

Query: 1067 YDIPKTEE---ASSGFLPGDRNKSRSTTELDDYSTNK--NGNNKYLDQIGNMTSSQRRSK 1121
              I K EE        +     K R   E       K      K  +Q   +   +   +
Sbjct: 488  EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQ 547

Query: 1122 KEQVPSGAELERQQILQEMRKR-TPLHNDNSWIRQRSASVNKE 1163
            +++   G + E+ Q  ++MR++   +      IR++   + ++
Sbjct: 548  EQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ 590



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 40/171 (23%), Positives = 84/171 (49%), Gaps = 19/171 (11%)

Query: 910  LLQEKYQREQEKLREEWQR--AKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEA 967
            L Q++ Q E + L +E Q   AK +A+ E ++  +    +       +  +E  +  WE 
Sbjct: 258  LPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR---LNQQQEEKMWRQEEKIQEWEE 314

Query: 968  TWSEGS-KSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQDQLVIERERK--------WE 1017
               E   K  ++E     +EE+ + QEE++ E + K + Q++++ E+E K        WE
Sbjct: 315  KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWE 374

Query: 1018 QQLQ----EEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPV 1064
            ++ +    EE+  ++ +   +E+KR  EE+ R+ E  +E   ++++    +
Sbjct: 375  KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 425



 Score = 35.4 bits (80), Expect = 0.37
 Identities = 37/234 (15%), Positives = 102/234 (43%), Gaps = 15/234 (6%)

Query: 334 DKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDV----QNLRQLRYEE 389
           +K E  RR     +  E +     L +K++ +   +   +   E+     Q  RQ +  +
Sbjct: 360 EKEEKMRR--LEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 417

Query: 390 MQKIKSQLKEQDQKWQDDLAK-WKDRRKSYTSDLQKKKEEREEIEKQALEKSK-RSSKTF 447
           M + + +++EQ++K ++   K W+   K +  +  +++E+R+E E+   ++ K R  +  
Sbjct: 418 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477

Query: 448 ---KEMLQDRES--QNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERV--EEK 500
              KE + ++E   + ++       +M+  ++ + E +        +   Q E++  +E+
Sbjct: 478 WRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEE 537

Query: 501 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQME 554
                 E+ +E      ++E+++  + ++  Q     +    +   + +  + E
Sbjct: 538 KIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQE 591



 Score = 35.0 bits (79), Expect = 0.49
 Identities = 33/205 (16%), Positives = 88/205 (42%), Gaps = 15/205 (7%)

Query: 329 RKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYE 388
           +++K  + E+  + W   +  + +    +  +    E   +   ++  E  + +R  R E
Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR--RQE 355

Query: 389 EM--QKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKT 446
           EM  +K +   + ++  W+ +    +   K +  +  +++EE+ + E++  E+ KR  + 
Sbjct: 356 EMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 415

Query: 447 FKEMLQDRESQNQKSTVPSR--------RRMYSFDDVLEEGKRPPTMTVSEASYQSERVE 498
            K   Q+ + + Q+  +  +         +++  + + EE KR       E   Q E++ 
Sbjct: 416 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR---QEQEEMWRQEEKIR 472

Query: 499 EKGATYPSEIPKEDSTTFAKREDRV 523
           E+   +  +    +     K+E++V
Sbjct: 473 EQEEIWRQKEKMHEQEKIRKQEEKV 497



 Score = 33.1 bits (74), Expect = 1.9
 Identities = 29/167 (17%), Positives = 74/167 (44%), Gaps = 17/167 (10%)

Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER------- 429
           E +    ++R EE ++ + ++  Q++K ++    W+ + K +  +  +K+EE+       
Sbjct: 444 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEK 503

Query: 430 ----EEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTM 485
               EE  ++  EK  R  +  +E  Q+ + + Q+  +  +  M   +   + G++   M
Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIRE--QEEKIREQEEKIREQEEMMQ-EQEEKMGEQEEKM 560

Query: 486 TVSEASYQSE---RVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQL 529
              E   + E   R +E+      E  +E      ++E+++  + ++
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEM 607


>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
          Length = 1564

 Score = 66.6 bits (161), Expect = 2e-10
 Identities = 62/290 (21%), Positives = 131/290 (45%), Gaps = 21/290 (7%)

Query: 884  SAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDE 943
            S+P R     +E  + + R ++  DR+   + +R +E+ RE  +  ++E ERE  +  + 
Sbjct: 642  SSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDRER 701

Query: 944  ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEER-RQPQEEVVHEDQGK 1002
            E             RE           E  K  DRE  R  + +R R+ + E   E + +
Sbjct: 702  E-----------KERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERE 750

Query: 1003 KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA--EEQKRQAEIERETSVRIYQY 1060
            + +++   ERER+ E++ + E+E++R +   +E++R    E++ +  +  RE    I + 
Sbjct: 751  REREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIRED 810

Query: 1061 RRPVDSYDIPKTE-----EASSGFLPGDRNKSRSTTELDDYST--NKNGNNKYLDQIGNM 1113
            R P D +D  K++     E S       + +   + + D Y++  +KN  ++ L Q+   
Sbjct: 811  RNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRP 870

Query: 1114 TSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1163
              S+  S            +++  +  RK +    +   ++++ +SV+K+
Sbjct: 871  QESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQ 920



 Score = 55.5 bits (132), Expect = 3e-07
 Identities = 144/720 (20%), Positives = 263/720 (36%), Gaps = 136/720 (18%)

Query: 334  DKHEDNRRSWASPVYTEA---DGTFSRLFQKIYGENGSKSM-------------SDV--S 375
            DK  D+RR     +  +    DG   R  +K Y   GS S              SD   S
Sbjct: 794  DKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNS 853

Query: 376  AEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQ 435
             +D     +L  + ++  +S+        +D   +WK+         + +K ER+E  ++
Sbjct: 854  GDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKE---------EDRKPERKESSRR 904

Query: 436  ALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSE 495
              E+        KE +   + Q +++ +    RM +  D++   +     T S+ ++   
Sbjct: 905  YEEQE------LKEKVSSVDKQREQTEILESSRMRA-QDIIGHHQSEDRET-SDRAHDEN 956

Query: 496  RVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMES 555
            + + K    P +  KED     +     T+E      SP + Q   S+   R +S     
Sbjct: 957  KKKAKIQKKPIKKKKEDDVGIERGNIETTSE-DGQVFSPKKGQKKKSIEKKRKKSKGDSD 1015

Query: 556  TRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRT 615
                 +  +S +K               G +T  I++      M +    NG +ED ++ 
Sbjct: 1016 ISDEEAAQQSKKKR--------------GPRTPPITTKEELVEMCNG--KNGILEDSQKK 1059

Query: 616  PNNVVS--TPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTS----PFSSLSQDQAAT 669
             +   S  +    PD +++     ++ E  AT       PSP S    P   ++   A T
Sbjct: 1060 EDTAFSDWSDEDVPDRTEV-----TEAEHTATATTPGSTPSPLSSLLPPPPPVATATATT 1114

Query: 670  SKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTI---- 725
              ATL++T+     S S                  S + IS + TP  + +  F      
Sbjct: 1115 VPATLAATTAAAATSFST-----------------SAITISTSATPTNTTNNTFANEDSH 1157

Query: 726  ---------KWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAK 776
                     K + P + +   +   P +    Q     +  N +  S+   +    +   
Sbjct: 1158 RKCHRTRVEKVETPHVTIEDAQHRKPMD----QKRSSSLGSNRSNRSHTSGRLRSPSNDS 1213

Query: 777  AQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQS--SNIESK 834
            A  +G      +R   +GS +             EK+ +L +T +    +        S+
Sbjct: 1214 AHRSGDDQSGRKRVLHSGSRDR------------EKTKSLEITGERKSRIDQLKRGEPSR 1261

Query: 835  EINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQE 894
              +    +S +  S+ S   S + +  RS     GS DS         +    R+  D+E
Sbjct: 1262 STSSDRQDSRSHSSRRSSPESDRQVHSRS-----GSFDSR------DRLQERDRYEHDRE 1310

Query: 895  EERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMS 954
             ER+R++  Q+E DR   + + R ++  R+  +  ++E ER+  + LD E   L S+S+ 
Sbjct: 1311 RERERRDTRQREWDRDADKDWPRNRD--RDRLRERERERERDKRRDLDRERERLISDSVE 1368

Query: 955  LTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERER 1014
                     T+E++  E  K    E    GE ER          D     +D L +++ER
Sbjct: 1369 RDRDRDRDRTFESSQIESVKRC--EAKLEGEHER----------DLESTSRDSLALDKER 1416



 Score = 51.2 bits (121), Expect = 7e-06
 Identities = 61/309 (19%), Positives = 123/309 (39%), Gaps = 30/309 (9%)

Query: 886  PSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEEL 945
            P R   DQ  +   + R  +   R  +E+ QR    +R   Q    E ER+  +  +E  
Sbjct: 609  PERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRH--QGRNDELERDERR--EERR 664

Query: 946  MVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQ 1005
            +    +      RE           E  +  +RE  R  E +R + +E  +  ++ ++ +
Sbjct: 665  VDRVDDRRDERARERD--------RERERDRERERERERERDREREKERELERERARERE 716

Query: 1006 DQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVD 1065
             +   ER+R+ ++    ++E++R +    E++R  E ++R+ E ERE      + R    
Sbjct: 717  REREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERER 776

Query: 1066 SYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQV 1125
            + +  K  E    +   D+ +     + ++   ++N  + +          +R+SKK   
Sbjct: 777  ARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGH---------DERKSKKRYR 827

Query: 1126 PSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMR----RGESLDNLD 1181
              G+   RQ       KR   H+ +S         N++   L  ++R    R  S  +L 
Sbjct: 828  NEGSPSPRQS-----PKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLT 882

Query: 1182 SPRSNSWRQ 1190
              R   W++
Sbjct: 883  EDRQGRWKE 891



 Score = 50.8 bits (120), Expect = 9e-06
 Identities = 81/387 (20%), Positives = 154/387 (39%), Gaps = 42/387 (10%)

Query: 893  QEEERKRQERWQKEQDRLLQEKYQREQEKLRE---EWQ---------RAKQEAERENSKY 940
            +E ER+R+   ++E++R  + +  RE++K RE   +W+         R K+E  RE+   
Sbjct: 754  EERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNP 813

Query: 941  LDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ 1000
             D       S         PS         E S  SD   +   + E+ +   +VV   +
Sbjct: 814  RDGH-DERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQE 872

Query: 1001 GKK-PQDQLVIERERKW--EQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRI 1057
             +      L  +R+ +W  E +  E +E  R   E E +++ +   K++ + E   S R+
Sbjct: 873  SRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRM 932

Query: 1058 YQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIG-NMTSS 1116
                R  D     ++E+  +     D NK ++  +       K       D +G    + 
Sbjct: 933  ----RAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKE------DDVGIERGNI 982

Query: 1117 QRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGES 1176
            +  S+  QV S  + ++++ +++ RK++   +D S       S  K     P I  + E 
Sbjct: 983  ETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEEL 1042

Query: 1177 LDNLDSPRSNSWRQPPWLNQPTGF--YASSSVQDFSRPPPQLVSTSNRAYMRNP------ 1228
            ++  +    N   +     + T F  ++   V D +    ++    + A    P      
Sbjct: 1043 VEMCNG--KNGILEDSQKKEDTAFSDWSDEDVPDRT----EVTEAEHTATATTPGSTPSP 1096

Query: 1229 -SSSVPPPSAGSVKTSTTGVATTQSPT 1254
             SS +PPP   +  T+TT  AT  + T
Sbjct: 1097 LSSLLPPPPPVATATATTVPATLAATT 1123



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 71/361 (19%), Positives = 138/361 (38%), Gaps = 35/361 (9%)

Query: 331  KKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDV----SAEDVQNLRQLR 386
            +KP++ E +RR     +  +      +  Q    E+      D+     +ED +   +  
Sbjct: 894  RKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAH 953

Query: 387  YEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKT 446
             E  +K K Q K   +K +DD+   +   ++ + D Q    ++ + +K+++EK ++ SK 
Sbjct: 954  DENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQ-KKKSIEKKRKKSKG 1012

Query: 447  FKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPS 506
              ++  +  +Q  K                + G R P +T  E     E    K      
Sbjct: 1013 DSDISDEEAAQQSKK---------------KRGPRTPPITTKEELV--EMCNGKNGILED 1055

Query: 507  EIPKEDSTTFAKREDR------VTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA 560
               KED T F+   D         TE +  + +     +P+ LSSL      + +T  + 
Sbjct: 1056 SQKKED-TAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPV-ATATAT 1113

Query: 561  SLPRSYRKTDTVRLTSVVTPR-PFGSQTRGISSLPRSYTMDDAWK--YNGDVEDIKRTPN 617
            ++P +   T     TS  T      +     ++   ++  +D+ +  +   VE ++    
Sbjct: 1114 TVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHV 1173

Query: 618  NVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSST 677
             +       P   + +SSL S +  +       RL SP++  +  S D  +  K  L S 
Sbjct: 1174 TIEDAQHRKPMDQKRSSSLGSNR--SNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSG 1231

Query: 678  S 678
            S
Sbjct: 1232 S 1232



 Score = 38.5 bits (88), Expect = 0.044
 Identities = 38/182 (20%), Positives = 74/182 (40%), Gaps = 27/182 (14%)

Query: 973  SKSSDREGTRAGEEERRQPQEE-VVHEDQGK-------KPQDQLVIERERK--------- 1015
            S SSDR+ +R+    R  P+ +  VH   G        + +D+   +RER+         
Sbjct: 1262 STSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQR 1321

Query: 1016 -WEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEE 1074
             W++   ++  + R +    E++R  E  KR+ +++RE    I          D  +T E
Sbjct: 1322 EWDRDADKDWPRNRDRDRLRERERERERDKRR-DLDRERERLISDSVERDRDRDRDRTFE 1380

Query: 1075 AS--------SGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVP 1126
            +S           L G+  +   +T  D  + +K   +K L  +     + +  + E + 
Sbjct: 1381 SSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLE 1440

Query: 1127 SG 1128
            +G
Sbjct: 1441 AG 1442



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 39/204 (19%), Positives = 80/204 (39%), Gaps = 17/204 (8%)

Query: 318 SRQPSY-VPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSA 376
           S  PS+ + +P RK+ P +H    R      +     +  R  ++     G +     S 
Sbjct: 372 SPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSR 431

Query: 377 EDVQNLRQLRYEEMQKIKSQLKE----QDQKWQDDLAKWKDRRKSYTS-DLQKKKEEREE 431
           E+ +      YE+ Q      ++    +D + + D    +DRR+   S D++  +E R+ 
Sbjct: 432 EERE------YEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDY 485

Query: 432 IEKQALEKSKRSSKTFKEM-----LQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMT 486
                  +  R S++ ++       + R++  ++ T P   R Y  + + EE  R     
Sbjct: 486 SRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRN 545

Query: 487 VSEASYQSERVEEKGATYPSEIPK 510
            S    +SE   ++       +P+
Sbjct: 546 ESRNESRSEIRNDRMGRSRGRVPE 569



 Score = 30.8 bits (68), Expect = 9.2
 Identities = 50/255 (19%), Positives = 90/255 (35%), Gaps = 42/255 (16%)

Query: 414 RRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFD 473
           R K Y+S+ ++  E      ++ ++  ++   T  +     ES +      SR R    +
Sbjct: 66  RGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKE 125

Query: 474 DVLEEGKRPPTMTVSEASYQSER-----------------VEEKGATYPSEIPKEDSTTF 516
           D+    +R P        +++ R                 +E K      E+ K +    
Sbjct: 126 DIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENM 185

Query: 517 AKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTS 576
            KRE+ +  + ++  +    + SP+      S+S + +S+  S+S  +  RKT  V    
Sbjct: 186 EKREE-IIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAV---- 240

Query: 577 VVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSL 636
                P   Q R               K N   +   RTP    S P P P+   L    
Sbjct: 241 ---SSPLLDQQRNS-------------KTNQSKKKGPRTP----SPPPPIPEDIALGKKY 280

Query: 637 SSQKEVAATEEDVTR 651
             + +V    E+ TR
Sbjct: 281 KEKYKVKDRIEEKTR 295



 Score = 30.8 bits (68), Expect = 9.2
 Identities = 49/260 (18%), Positives = 102/260 (39%), Gaps = 12/260 (4%)

Query: 386 RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKK--KEEREEIEKQALEKSKRS 443
           R +E  + + + +E+D++ + +  + +DR +    +L+++  +E   E EK+   +  R 
Sbjct: 671 RRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRD 730

Query: 444 SKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGAT 503
               +E  ++RE   +K     R       +   E +R        A  + +  E +   
Sbjct: 731 RDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDW 790

Query: 504 YPSEIPKEDSTTFAK--REDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSAS 561
              +  ++D     +  REDR   +     +S    ++  S S  +S   + E +  S +
Sbjct: 791 EDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDA 850

Query: 562 LPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVS 621
                 K +  RL S V  RP   ++R +S    +      WK     E+ ++      S
Sbjct: 851 YNSGDDKNEKHRLLSQVV-RP--QESRSLSPSHLTEDRQGRWK-----EEDRKPERKESS 902

Query: 622 TPAPSPDASQLASSLSSQKE 641
                 +  +  SS+  Q+E
Sbjct: 903 RRYEEQELKEKVSSVDKQRE 922


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 69/272 (25%), Positives = 131/272 (48%), Gaps = 29/272 (10%)

Query: 802  DATSGIYNSEKSSN------------LSVTTDFSESLQSSNIESKEINGIHDESNAFESK 849
            D+ +GIY   ++S+            L+V  D S ++ S   E+  IN +   S   E K
Sbjct: 68   DSATGIYGEGRASSTTLEDLESQYQELAVALDSSSAIISQLTEN--INSLVRTSK--EEK 123

Query: 850  ASESISLKNLKRRSQFFEQGSSDSVVPDLP-----VPTISAPSRWVWDQEEERKRQERWQ 904
              E   ++ L R     +  +++ + P+ P     V  +   +  +  + E   RQ + +
Sbjct: 124  KHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAE 183

Query: 905  KEQDRLLQEKYQREQEKLREEWQRAKQEAER--ENSKYLDEELMVLSSNSMSLTTREPSL 962
             E +++L    +R++E+LRE+ +R +++ ER  E  + L E+   L      L  +E  L
Sbjct: 184  VENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERL 243

Query: 963  ATWEATWSEGSKS-SDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQ 1021
               E    E  +   ++E     +EER + QEE +HE + +  + +   ER R+ E++L 
Sbjct: 244  CEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQE---ERLREQEERLC 300

Query: 1022 EEQEQKRLQAE--AEEQKRPAEEQKRQAEIER 1051
            E++E+ R Q E   E+++R  E+++R  E E+
Sbjct: 301  EQEERLREQEERLCEQEERLREQEERLCEQEK 332



 Score = 57.8 bits (138), Expect = 7e-08
 Identities = 77/316 (24%), Positives = 132/316 (41%), Gaps = 29/316 (9%)

Query: 824  ESLQS-SNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPT 882
            E LQ  +N   KE+  +  +  A E + ++ +SL N ++  +  EQ              
Sbjct: 160  EQLQDETNHLRKELESVGRQLQA-EVENNQMLSLLNRRQEERLREQEER----------- 207

Query: 883  ISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQR---EQEKLREEWQRAKQEAER--EN 937
            +      + +QEE    QE   +EQ+  L+E+ +R   ++E+LRE  +R  ++ ER  E 
Sbjct: 208  LREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQ 267

Query: 938  SKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVH 997
             + L E+   L      L  +E  L   E    E  +    +  R  E+E R  ++E   
Sbjct: 268  EERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERL 327

Query: 998  EDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRI 1057
             +Q K P  + ++E   K  +Q + ++EQ+RL  E E      EE   Q  + R+   R+
Sbjct: 328  CEQEKLPGQERLLEEVEKLLEQERRQEEQERL-LERERLLEEVEELLEQERL-RQQDERL 385

Query: 1058 YQYRRPVDSYDIPKTE---EASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMT 1114
            +Q     +   + + E   E     L   R + RS  E        N  NK   Q+    
Sbjct: 386  WQQETLQELERLRELERMLELGWEALYEQRAEPRSGFE------ELNNENKSTLQLEQQV 439

Query: 1115 SSQRRSKKEQVPSGAE 1130
               ++S   + P G+E
Sbjct: 440  KELKKSGGAEEPRGSE 455



 Score = 31.6 bits (70), Expect = 5.4
 Identities = 33/188 (17%), Positives = 83/188 (44%), Gaps = 11/188 (5%)

Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEI-EKQALEKSKRSSKT 446
           E + + + +L+EQ+++  +   + +++ +      ++ +E+ E + E++ L   +R  + 
Sbjct: 283 ERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEE 342

Query: 447 FKEML-QDRESQNQKSTVPSRRRMYSFDDVLEEGK---------RPPTMTVSEASYQSER 496
            +++L Q+R  + Q+  +   R +   +++LE+ +         +  T+   E   + ER
Sbjct: 343 VEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELER 402

Query: 497 VEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMEST 556
           + E G     E   E  + F +  +   + +QL  Q    ++S  +     S S      
Sbjct: 403 MLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEPRGSESAAAARP 462

Query: 557 RVSASLPR 564
              A +P+
Sbjct: 463 VAGAPVPQ 470


>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
          Length = 2817

 Score = 65.9 bits (159), Expect = 3e-10
 Identities = 64/262 (24%), Positives = 120/262 (45%), Gaps = 30/262 (11%)

Query: 809  NSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQ 868
            NS K +N   + D       +N   KE + + +  ++ +  A  S++     +   F ++
Sbjct: 343  NSPKENN---SEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQE 399

Query: 869  GSSDSVVPDLP--------------VPTISAP---SRWVWDQEEERKRQERWQKEQDRLL 911
              + S +P  P              VP    P    + V D++E  K++ R Q E    +
Sbjct: 400  RGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAV 459

Query: 912  QE-KYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWS 970
            +  + +RE+E+ R E QR    AE+   K LDE+L +L         RE           
Sbjct: 460  ERARKRREEEERRMEEQRKAACAEK--LKRLDEKLGILEKQPSPEEIREREREKEREREK 517

Query: 971  EGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQ 1030
            E  K  ++E  +  E++R + QE+   ++  K+ + Q  +E+ERK     QE++++   Q
Sbjct: 518  ELEKEQEQEREKEREKDRERQQEK--EKELEKEQEKQREMEKERK-----QEKEKELERQ 570

Query: 1031 AEAEEQKRPAEEQKRQAEIERE 1052
             E E++ +  +EQ+++ E+E+E
Sbjct: 571  KEKEKELQKMKEQEKECELEKE 592



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 52/231 (22%), Positives = 96/231 (41%), Gaps = 20/231 (8%)

Query: 317 KSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSA 376
           + RQ S + A + + +  + E+ RR         A+    RL +K+       S  ++  
Sbjct: 448 RRRQQSEISAAVERARKRREEEERRMEEQRKAACAE-KLKRLDEKLGILEKQPSPEEIRE 506

Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIE--- 433
            +       R +E ++ K   KEQ+Q+ + +  K ++R++    +L+K++E++ E+E   
Sbjct: 507 RE-------REKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKER 559

Query: 434 KQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQ 493
           KQ  EK     K  ++ LQ  + Q ++  +   R          E    P +   E+   
Sbjct: 560 KQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENS 619

Query: 494 SERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLS 544
             + EE   T      ++DS    K    V  E +  S S   +  PA LS
Sbjct: 620 CNKEEEPVFT------RQDSNRSEKEATPVVHETEPESGS---QPRPAVLS 661



 Score = 38.9 bits (89), Expect = 0.034
 Identities = 38/157 (24%), Positives = 79/157 (50%), Gaps = 31/157 (19%)

Query: 892  DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 951
            ++++E++++   QKE+++ LQ        K++E+ +  + E ERE    L+E+       
Sbjct: 558  ERKQEKEKELERQKEKEKELQ--------KMKEQEKECELEKEREK---LEEK------- 599

Query: 952  SMSLTTREPSLATW-EATWSEGSKSSDREGTRAGEEERRQPQE--EVVHE---DQGKKPQ 1005
               +  REP+L    E   SE S + + E     ++  R  +E   VVHE   + G +P+
Sbjct: 600  ---IEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPR 656

Query: 1006 DQLVIERERKWEQQL----QEEQEQKRLQAEAEEQKR 1038
              ++    +++++ L    Q +QEQ + Q   ++Q++
Sbjct: 657  PAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQ 693



 Score = 32.3 bits (72), Expect = 3.2
 Identities = 32/150 (21%), Positives = 62/150 (41%), Gaps = 13/150 (8%)

Query: 394 KSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS-----KTFK 448
           K Q+ ++D+ W     K + R++S  S   ++  +R E E++ +E+ ++++     K   
Sbjct: 435 KQQVADEDEIW-----KQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLD 489

Query: 449 EMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEI 508
           E L   E Q     +  R R    +   E  K        E     ER +EK      E 
Sbjct: 490 EKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQ 549

Query: 509 PKEDSTTFAKREDRVTTEIQLPSQSPVEEQ 538
            K+      +++++   E +L  Q   E++
Sbjct: 550 EKQREMEKERKQEK---EKELERQKEKEKE 576


>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo
            sapiens]
          Length = 624

 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 83/377 (22%), Positives = 156/377 (41%), Gaps = 38/377 (10%)

Query: 814  SNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDS 873
            SN ++      + Q++  E +E+     E+ +F S A E  S K+ +R+      G S S
Sbjct: 256  SNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKG-----GRSRS 310

Query: 874  VVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEA 933
                       + SR        RKR +   K + R       R++++ R +    K+  
Sbjct: 311  HT--------RSKSRSSSKSHSRRKRSQ--SKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 360

Query: 934  ERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE 993
             RE  K          S      TRE      +    E  K  DRE  R  E+ER + +E
Sbjct: 361  SRERRKSRSRS----HSRDKRKDTRE------KIKEKERVKEKDREKEREREKEREKEKE 410

Query: 994  EVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1053
               ++D+ K+ +     ++E+  E++ ++E E+ R + + +EQ +  E +K +++   E 
Sbjct: 411  RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 470

Query: 1054 SVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNM 1113
              +  + R P  SY+  +   +SS      R++S S +     +  +  +     +  N 
Sbjct: 471  RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 530

Query: 1114 TSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV-----NKEPVSLP 1168
               +R  +++ +    E ER      MRK +   +    + + S S+     NKEP S  
Sbjct: 531  KDKKREKERDHISERRERERS---TSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS-- 585

Query: 1169 GIMRRGESLDNLDSPRS 1185
                  + +D+ D+PR+
Sbjct: 586  ---SVSKEVDDKDAPRT 599



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 37/191 (19%), Positives = 92/191 (48%), Gaps = 15/191 (7%)

Query: 892  DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 951
            D+E E+ R++  +K+++R  +++++++++K +E+ Q  ++E E++ SK +DE+       
Sbjct: 418  DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK------R 471

Query: 952  SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIE 1011
                 +R P   ++ A+    S S +R   R+    R     + +     + P  +   +
Sbjct: 472  KKDKKSRTPP-RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 530

Query: 1012 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP-------- 1063
            +++K E++     E++  +     +K   +   ++   +  TS++  ++ +         
Sbjct: 531  KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 590

Query: 1064 VDSYDIPKTEE 1074
            VD  D P+TEE
Sbjct: 591  VDDKDAPRTEE 601



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 51/243 (20%), Positives = 99/243 (40%), Gaps = 11/243 (4%)

Query: 350 EADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLA 409
           EA    S   +   G++  +      +      R       ++ +SQ K + +      +
Sbjct: 284 EAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRS 343

Query: 410 KWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRM 469
           + KDRR+S  S  +K+ + RE  + ++   S+   K  +E ++++E   +K     R R 
Sbjct: 344 RQKDRRRS-KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERERE 402

Query: 470 YSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRV------ 523
              +   E GK        E   + ++ +++      E  K+      K +D+       
Sbjct: 403 KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 462

Query: 524 -TTEIQLPSQSPVEEQSP--ASLSSLRSRSTQME-STRVSASLPRSYRKTDTVRLTSVVT 579
            + EI    +   + ++P  +  +S RSRS+  E   R S S  RS R + T++  S  +
Sbjct: 463 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 522

Query: 580 PRP 582
           P P
Sbjct: 523 PSP 525



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 48/231 (20%), Positives = 90/231 (38%), Gaps = 14/231 (6%)

Query: 386 RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSK 445
           R +E  + K + +E++++ + +  K KDR K    D +K KE+  E E++   +  R  +
Sbjct: 389 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE 448

Query: 446 TFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKR----PPTMTVSEASYQSERVEEKG 501
             KE  QD+E + +K       R    D+  ++ K+    P +   S  S  S R   + 
Sbjct: 449 --KEKEQDKEKEREKD------RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 500

Query: 502 ATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSL--RSRSTQMESTRVS 559
            +  S      S T  ++  R  +      +    E+    +S    R RST M  +   
Sbjct: 501 RSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSND 560

Query: 560 ASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVE 610
                   K  T          P  S ++ +       T ++  ++NG+ +
Sbjct: 561 RDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQ 611


>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo
            sapiens]
          Length = 508

 Score = 65.5 bits (158), Expect = 3e-10
 Identities = 83/377 (22%), Positives = 156/377 (41%), Gaps = 38/377 (10%)

Query: 814  SNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDS 873
            SN ++      + Q++  E +E+     E+ +F S A E  S K+ +R+      G S S
Sbjct: 140  SNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKG-----GRSRS 194

Query: 874  VVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEA 933
                       + SR        RKR +   K + R       R++++ R +    K+  
Sbjct: 195  HT--------RSKSRSSSKSHSRRKRSQ--SKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 244

Query: 934  ERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE 993
             RE  K          S      TRE      +    E  K  DRE  R  E+ER + +E
Sbjct: 245  SRERRKSRSRS----HSRDKRKDTRE------KIKEKERVKEKDREKEREREKEREKEKE 294

Query: 994  EVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1053
               ++D+ K+ +     ++E+  E++ ++E E+ R + + +EQ +  E +K +++   E 
Sbjct: 295  RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 354

Query: 1054 SVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNM 1113
              +  + R P  SY+  +   +SS      R++S S +     +  +  +     +  N 
Sbjct: 355  RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 414

Query: 1114 TSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV-----NKEPVSLP 1168
               +R  +++ +    E ER      MRK +   +    + + S S+     NKEP S  
Sbjct: 415  KDKKREKERDHISERRERERS---TSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS-- 469

Query: 1169 GIMRRGESLDNLDSPRS 1185
                  + +D+ D+PR+
Sbjct: 470  ---SVSKEVDDKDAPRT 483



 Score = 57.4 bits (137), Expect = 9e-08
 Identities = 37/191 (19%), Positives = 92/191 (48%), Gaps = 15/191 (7%)

Query: 892  DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 951
            D+E E+ R++  +K+++R  +++++++++K +E+ Q  ++E E++ SK +DE+       
Sbjct: 302  DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK------R 355

Query: 952  SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIE 1011
                 +R P   ++ A+    S S +R   R+    R     + +     + P  +   +
Sbjct: 356  KKDKKSRTPP-RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 414

Query: 1012 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP-------- 1063
            +++K E++     E++  +     +K   +   ++   +  TS++  ++ +         
Sbjct: 415  KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 474

Query: 1064 VDSYDIPKTEE 1074
            VD  D P+TEE
Sbjct: 475  VDDKDAPRTEE 485



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 51/243 (20%), Positives = 99/243 (40%), Gaps = 11/243 (4%)

Query: 350 EADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLA 409
           EA    S   +   G++  +      +      R       ++ +SQ K + +      +
Sbjct: 168 EAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRS 227

Query: 410 KWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRM 469
           + KDRR+S  S  +K+ + RE  + ++   S+   K  +E ++++E   +K     R R 
Sbjct: 228 RQKDRRRS-KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERERE 286

Query: 470 YSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRV------ 523
              +   E GK        E   + ++ +++      E  K+      K +D+       
Sbjct: 287 KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 346

Query: 524 -TTEIQLPSQSPVEEQSP--ASLSSLRSRSTQME-STRVSASLPRSYRKTDTVRLTSVVT 579
            + EI    +   + ++P  +  +S RSRS+  E   R S S  RS R + T++  S  +
Sbjct: 347 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 406

Query: 580 PRP 582
           P P
Sbjct: 407 PSP 409



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 48/231 (20%), Positives = 90/231 (38%), Gaps = 14/231 (6%)

Query: 386 RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSK 445
           R +E  + K + +E++++ + +  K KDR K    D +K KE+  E E++   +  R  +
Sbjct: 273 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE 332

Query: 446 TFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKR----PPTMTVSEASYQSERVEEKG 501
             KE  QD+E + +K       R    D+  ++ K+    P +   S  S  S R   + 
Sbjct: 333 --KEKEQDKEKEREKD------RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 384

Query: 502 ATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSL--RSRSTQMESTRVS 559
            +  S      S T  ++  R  +      +    E+    +S    R RST M  +   
Sbjct: 385 RSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSND 444

Query: 560 ASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVE 610
                   K  T          P  S ++ +       T ++  ++NG+ +
Sbjct: 445 RDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQ 495


>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
          Length = 843

 Score = 65.1 bits (157), Expect = 4e-10
 Identities = 75/365 (20%), Positives = 161/365 (44%), Gaps = 40/365 (10%)

Query: 817  SVTTDFSESL-QSSNIESKEING-----IHDESNAFESKASESISLKNLKRRSQFFEQGS 870
            +VT D  E+L + +    + I G     I + S+   + + ES S    K++ +  +   
Sbjct: 187  TVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFR 246

Query: 871  SDSVVPDLPVPTISAPSRWVWDQEEERK-----------------RQERWQKEQDRLLQE 913
               V P +P P I+       + EE+++                  +E+ +KE++R   E
Sbjct: 247  RFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIE 306

Query: 914  KYQREQEKLRE-EWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEG 972
            K +RE+E+ RE E +R ++E ERE  +  ++E             R+ +         E 
Sbjct: 307  KERRERERERERERERREREREREREREREKEKERERERERD-RDRDRTKERDRDRDRER 365

Query: 973  SKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAE 1032
             +  DRE +    ++R + +E+    ++ ++ + +   ERER+ E++ + E+E++R +  
Sbjct: 366  DRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERER 425

Query: 1033 AEEQKRPAEEQKRQA----EIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSR 1088
             +++KR  EE +  A    ++ER+   +   Y+  + +++I + ++        +R + R
Sbjct: 426  EKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEER 485

Query: 1089 STTE----------LDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQ 1138
                          L+DY  +++    Y           R  + E      + E+++ L+
Sbjct: 486  RREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEE-LE 544

Query: 1139 EMRKR 1143
            E+R+R
Sbjct: 545  EIRQR 549



 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 39/187 (20%), Positives = 78/187 (41%), Gaps = 24/187 (12%)

Query: 389 EMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKR------ 442
           E +K++ +L+E++  +Q+ L  W+ R +  T + +K+ E  EE  ++  +++KR      
Sbjct: 442 ERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLE 501

Query: 443 ------------SSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDV----LEEGKRPPTMT 486
                            ++ L+DRE + +      +R     +++    L EG   P   
Sbjct: 502 DYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAE 561

Query: 487 VSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDR--VTTEIQLPSQSPVEEQSPASLS 544
           +     ++ER  +       E  +E+     K E R     E + P Q P  + +   +S
Sbjct: 562 LQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPIS 621

Query: 545 SLRSRST 551
           S  S S+
Sbjct: 622 SAPSVSS 628



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 45/205 (21%), Positives = 91/205 (44%), Gaps = 20/205 (9%)

Query: 892  DQEE--ERKRQERWQKEQDRLLQEKYQ----REQEKLREEWQRAKQEAERENSKYLDEEL 945
            D+E+  ER++ ER  +E++   QE+ +    RE++K RE  + A++E ER      + + 
Sbjct: 436  DEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKR 495

Query: 946  MVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK--- 1002
            +            +P      A      +  DRE     +E  R+ ++E + E + +   
Sbjct: 496  LKEFLEDYDDDRDDPKYYRGSALQK---RLRDREKEMEADERDRKREKEELEEIRQRLLA 552

Query: 1003 --KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVR---- 1056
               P     ++R  +  ++ ++ Q ++  ++E EE+++  +E+KR+  +E E        
Sbjct: 553  EGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPC 612

Query: 1057 IYQYRRPVDSYDIPKTEEASSGFLP 1081
            +    RP+ S   P    AS    P
Sbjct: 613  LKPTLRPISS--APSVSSASGNATP 635



 Score = 45.1 bits (105), Expect = 5e-04
 Identities = 77/351 (21%), Positives = 127/351 (36%), Gaps = 44/351 (12%)

Query: 386 RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSK 445
           R +E  + + + +++D+  +    + KDR +S      +++E   E E++   + +R  +
Sbjct: 353 RTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERE 412

Query: 446 TFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSE------RVEE 499
             +E  ++RE + +K     R R    +D  E  K    +   EA+YQ        R  +
Sbjct: 413 REREREREREREREKDK--KRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERK 470

Query: 500 KGATYPSEIPKEDS-----TTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQME 554
           K   Y  E  +E+         AKR      +       P   +  A    LR R  +ME
Sbjct: 471 KTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEME 530

Query: 555 STRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKR 614
           +        +   +    RL +   P P                  DA     + E  +R
Sbjct: 531 ADERDRKREKEELEEIRQRLLAEGHPDP------------------DAELQRMEQEAERR 572

Query: 615 TPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLP--SPT-SPFSSLSQDQAATSK 671
               +   P    +  +       ++E    EE+  + P   PT  P SS     +A+  
Sbjct: 573 RQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGN 632

Query: 672 ATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFG 722
           AT  +T G     ES  G I P  E S  Q Q  + R  I    G SL  G
Sbjct: 633 AT-PNTPG----DESPCGIIIP-HENSPDQQQPEEHRPKI----GLSLKLG 673



 Score = 37.4 bits (85), Expect = 0.098
 Identities = 15/62 (24%), Positives = 35/62 (56%)

Query: 407 DLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSR 466
           +++K++D  K    +  KK++ER+EIEK+  E+ +   +  +   ++RE + ++     +
Sbjct: 280 EISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEK 339

Query: 467 RR 468
            R
Sbjct: 340 ER 341



 Score = 36.2 bits (82), Expect = 0.22
 Identities = 43/219 (19%), Positives = 81/219 (36%), Gaps = 26/219 (11%)

Query: 329 RKKKPDKHEDNRRSWAS------PVYTEAD------------------GTFSRLFQKIYG 364
           RKKK +K ED  R +        P+ T+ D                    F    +K+  
Sbjct: 234 RKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEE 293

Query: 365 ENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQK 424
           E G K       E  +  R+   E  ++ + + +E++++ + +  K ++R +    D  +
Sbjct: 294 EKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDR 353

Query: 425 KKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPT 484
            KE   + +++      R  +   +  +DR    +KS    R R    +   E  +    
Sbjct: 354 TKERDRDRDRE--RDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERER 411

Query: 485 MTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRV 523
               E   + ER  EK      E  +ED+    K E ++
Sbjct: 412 EREREREREREREREKDKKRDREEDEEDAYERRKLERKL 450



 Score = 31.6 bits (70), Expect = 5.4
 Identities = 42/189 (22%), Positives = 72/189 (38%), Gaps = 28/189 (14%)

Query: 822 FSESLQSSNI-ESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPV 880
           + E L++  I E K+      E+   E +  E    K  KR  +F E    D    D   
Sbjct: 457 YQERLKNWEIRERKKTREYEKEAEREEERRREMA--KEAKRLKEFLEDYDDDR--DDPKY 512

Query: 881 PTISAPSRWVWDQEEERKRQERWQK-----------------------EQDRLLQEKYQR 917
              SA  + + D+E+E +  ER +K                       E  R+ QE  +R
Sbjct: 513 YRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERR 572

Query: 918 EQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSD 977
            Q ++++E +  ++E E++  +   EE M            +P+L    +  S  S S +
Sbjct: 573 RQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGN 632

Query: 978 REGTRAGEE 986
                 G+E
Sbjct: 633 ATPNTPGDE 641



 Score = 30.8 bits (68), Expect = 9.2
 Identities = 30/176 (17%), Positives = 66/176 (37%), Gaps = 3/176 (1%)

Query: 395 SQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDR 454
           S+ ++  +K +++  K +  R+    + ++++ ERE   ++   + +R  +  +E  ++R
Sbjct: 282 SKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKER 341

Query: 455 ESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDST 514
           E + ++     R +    D   E  +       S+ +    R  EK      E  +E   
Sbjct: 342 ERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERE- 400

Query: 515 TFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTD 570
              +RE     E +   +   E +        R R    E       L R  R+ +
Sbjct: 401 --REREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKE 454


>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 238

 Score = 64.3 bits (155), Expect = 8e-10
 Identities = 48/181 (26%), Positives = 94/181 (51%), Gaps = 21/181 (11%)

Query: 893  QEEERKRQ-ERWQKEQDRLL---QEKYQREQEKLREE----WQRAKQEAERENSKYLDEE 944
            +EEER R+ E+  +E++ ++   +EK Q ++EK+RE+    W++ ++  E+E   +  EE
Sbjct: 2    REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61

Query: 945  LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEE---------ERRQPQEEV 995
             M      M    R P     E  W +  +  ++E     ++         E+++ QEE 
Sbjct: 62   KMWEQEEKMWEQQRLPEQK--EKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119

Query: 996  VHEDQGK-KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETS 1054
            + E + K + Q++++ E+E K ++Q ++  EQ+    E EE+ R  +E+K Q + E+   
Sbjct: 120  MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR-EQEEKMQGQEEKMRD 178

Query: 1055 V 1055
            V
Sbjct: 179  V 179



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 49/161 (30%), Positives = 82/161 (50%), Gaps = 24/161 (14%)

Query: 890  VWDQEEERKRQER--WQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMV 947
            +W+QEE+ + QE   W++E+    QE+   EQ++L E+ ++  ++ ER   K   EE M 
Sbjct: 42   MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREK---EERM- 97

Query: 948  LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQ 1007
                      RE  +  W+       K   +E     +EE+ Q QEE++ E Q +K Q+Q
Sbjct: 98   ----------REQKM--WQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWE-QEEKMQEQ 144

Query: 1008 LVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAE 1048
                 E+ WEQ+ ++ +EQ+    E EE+ +  EE+ R  E
Sbjct: 145  ----EEKMWEQE-EKMREQEEKMREQEEKMQGQEEKMRDVE 180



 Score = 40.8 bits (94), Expect = 0.009
 Identities = 30/123 (24%), Positives = 64/123 (52%), Gaps = 14/123 (11%)

Query: 388 EEMQKIKSQLKEQDQK-WQDDLAKWKDRR------KSYTSDLQ-KKKEEREEIEK--QAL 437
           E+MQ+ + ++ EQ++K W+ +   W+ +R      K +  D + ++KEER   +K  Q +
Sbjct: 47  EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQV 106

Query: 438 EKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERV 497
           EK +   KT +E +Q++E + Q+        M+  ++ ++E +        +   Q E++
Sbjct: 107 EKMREKKKTQEEKMQEQEEKMQE----QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 162

Query: 498 EEK 500
            E+
Sbjct: 163 REQ 165



 Score = 32.3 bits (72), Expect = 3.2
 Identities = 26/157 (16%), Positives = 74/157 (47%), Gaps = 8/157 (5%)

Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQ-KWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQ 435
           E+ + +R+ + E+MQ+ + +++EQ++  W+ +    +   K +  + +  ++E +  E+Q
Sbjct: 16  EEEEMMRE-QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQ 74

Query: 436 ALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSE 495
            L + K       E L+++E + ++      ++M+   + + E K+     + E   + +
Sbjct: 75  RLPEQKEKMWEQDERLREKEERMRE------QKMWQQVEKMREKKKTQEEKMQEQEEKMQ 128

Query: 496 RVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQ 532
             EE       ++ +++   + + E     E ++  Q
Sbjct: 129 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 165



 Score = 32.0 bits (71), Expect = 4.1
 Identities = 31/159 (19%), Positives = 67/159 (42%), Gaps = 9/159 (5%)

Query: 1011 ERERKWEQQLQEEQEQKRLQAE---AEEQKRPAEEQK--RQAEIERETSVRIYQYRRPVD 1065
            ER R+ E++++EE+E  R Q E    +E+K   +E+K   Q E  +E   ++++    + 
Sbjct: 5    ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 64

Query: 1066 SYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQR-RSKKEQ 1124
              +    E+     LP  + K     E       +    K   Q+  M   ++ + +K Q
Sbjct: 65   EQEEKMWEQQR---LPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121

Query: 1125 VPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1163
                   E+++++ E  ++     +  W ++      +E
Sbjct: 122  EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 160


>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
            sapiens]
          Length = 600

 Score = 63.9 bits (154), Expect = 1e-09
 Identities = 57/263 (21%), Positives = 112/263 (42%), Gaps = 25/263 (9%)

Query: 893  QEEERKRQERW-QKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 951
            +E ER+R++R  ++E DR  + + ++++ + R+  +  +++ E+E  +  D E       
Sbjct: 60   KERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE------- 112

Query: 952  SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIE 1011
                  R+           E  + ++REG R  + +    +E     D  K+ + Q   E
Sbjct: 113  ------RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE 166

Query: 1012 RERKWEQQLQEEQEQKRLQAEAEEQKRPAE----------EQKRQAEIERETSVRIYQYR 1061
            R+R+ E+  Q+E+E+++ + E  E++R  E          E+ R+ E ERET     + R
Sbjct: 167  RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR 226

Query: 1062 RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQR-RS 1120
            +     D  +  E            S   TE D     +   ++  D+       Q  R 
Sbjct: 227  QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286

Query: 1121 KKEQVPSGAELERQQILQEMRKR 1143
            ++ +     E ER++  Q  R+R
Sbjct: 287  RQRRTERDRETERKRERQRERER 309



 Score = 63.2 bits (152), Expect = 2e-09
 Identities = 66/273 (24%), Positives = 117/273 (42%), Gaps = 26/273 (9%)

Query: 892  DQEEERKRQERWQKEQDRLLQEKYQREQEKLRE-EWQRAKQEAE-RENSKYLDEELMVLS 949
            D + ER+RQ   +KE++R    + QR+ E+ R+ E +R K   E RE  +  ++E     
Sbjct: 144  DGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED 203

Query: 950  SNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEER---RQPQEEVVHE---DQGKK 1003
             +S     RE    T   T +E  + +DRE  R  + ER   +Q + E   E   ++ K+
Sbjct: 204  RHSERGRERERERET--ETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKE 261

Query: 1004 PQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP 1063
             + +   +R+R   Q+ +E Q  ++ Q   E  +    +++RQ E ERE      + R  
Sbjct: 262  RERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERER 321

Query: 1064 VDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKE 1123
                +  +  E           K +  TE+D     + G              +R++++E
Sbjct: 322  ERERERERQRETERDREKERERKRKRQTEMDRERNRQTGR-----------EGRRQAERE 370

Query: 1124 QVPSGAELERQQILQEMRKRTPLHNDNSWIRQR 1156
            +     E ER++  Q  R+R     D    RQ+
Sbjct: 371  R-----ERERERDRQSAREREERERDRDRDRQK 398



 Score = 56.6 bits (135), Expect = 2e-07
 Identities = 49/196 (25%), Positives = 87/196 (44%), Gaps = 23/196 (11%)

Query: 892  DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 951
            ++E  RKR+   ++E++R  Q + +R++EK RE  ++ + E +RE ++    E    +  
Sbjct: 310  ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAER 369

Query: 952  SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIE 1011
                  RE       A   E  +  DR+  R  E ER+  +                  +
Sbjct: 370  ERE---RERERDRQSARERE-ERERDRDRDRQKERERQTEK------------------D 407

Query: 1012 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQK-RQAEIERETSVRIYQYRRPVDSYDIP 1070
            R+ + E + Q E+E+ R      E+ R  E+QK R+ + ER+T  +  + R+    Y  P
Sbjct: 408  RDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNP 467

Query: 1071 KTEEASSGFLPGDRNK 1086
                A SG +  D N+
Sbjct: 468  PPRTARSGVVQSDPNR 483



 Score = 56.2 bits (134), Expect = 2e-07
 Identities = 51/218 (23%), Positives = 91/218 (41%), Gaps = 46/218 (21%)

Query: 892  DQEEERKR-----QERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELM 946
            D+E ER+R     ++R QKE++R    K QR  E+ RE  ++ +++ ERE  +       
Sbjct: 259  DKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER------- 311

Query: 947  VLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQD 1006
                                    E ++  +RE  R  E ER++  E    +++ +K + 
Sbjct: 312  ------------------------ERNRKRERERERERERERQRETERDREKERERKRKR 347

Query: 1007 QLVIERER----------KWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVR 1056
            Q  ++RER          + E++ + E+E+ R  A   E++    ++ RQ E ER+T   
Sbjct: 348  QTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKD 407

Query: 1057 IYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELD 1094
                R      +  K  E+  G   G   + +   E D
Sbjct: 408  RDGQRETEKQREREKDRESERGRERGREREKQKGRERD 445



 Score = 48.1 bits (113), Expect = 6e-05
 Identities = 37/164 (22%), Positives = 74/164 (45%), Gaps = 2/164 (1%)

Query: 892  DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 951
            ++E ER+RQ   ++++++  + K +R+ E  RE  ++  +E  R+  +  + E      +
Sbjct: 322  ERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQS 381

Query: 952  SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEE--ERRQPQEEVVHEDQGKKPQDQLV 1009
            +     RE           E     DR+G R  E+  ER + +E     ++G++ + Q  
Sbjct: 382  AREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKG 441

Query: 1010 IERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1053
             ER+R+ +   Q  +++KR         R A     Q++  R T
Sbjct: 442  RERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPT 485



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 55/230 (23%), Positives = 89/230 (38%), Gaps = 22/230 (9%)

Query: 977  DREGTRAGEEERRQPQEEVVHEDQGKKP---QDQLVIERERKWEQQLQEEQEQKRLQAEA 1033
            DRE  R  E ERR+ + +   E   K+    +     +R+R  E+Q   E+E++R Q + 
Sbjct: 53   DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERER-QTDR 111

Query: 1034 EEQKRPAEEQKRQAEIERETSVRIYQYR-RPVDSY-------DIPKTEEASSGFLPGDRN 1085
            E  ++  +E+ RQ E ERET     + R R  D         D  K  E  +     DR 
Sbjct: 112  ERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQT-----DRE 166

Query: 1086 KSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQ---EMRK 1142
            + R T         +  N +   +       + +++      G E ER++  +   E ++
Sbjct: 167  RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR 226

Query: 1143 RTPLHND--NSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQ 1190
            +T    D      R+R     +E  S     R  E     D  R    RQ
Sbjct: 227  QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQ 276



 Score = 44.7 bits (104), Expect = 6e-04
 Identities = 43/239 (17%), Positives = 94/239 (39%), Gaps = 11/239 (4%)

Query: 324 VPAPLRKKKPDKHEDNRRSWASPVYTEADGTF-SRLFQKIYGENGSKSMSDVSAEDVQNL 382
           +P    +++P   E  RR      + +ADG    R  QK       K  ++   +  +  
Sbjct: 22  IPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRER 81

Query: 383 RQL--RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS 440
           R+   R+ +  + + + ++++++ +    + +DR++    + QK++E   E E +     
Sbjct: 82  RREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDR 141

Query: 441 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 500
           +   +  +E  +D E + ++ T   R+R    +   E  +        E + Q  R  E+
Sbjct: 142 QTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERER--------EKNRQERRERER 193

Query: 501 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVS 559
                ++     S    +RE    TE +   +   + +      + R R  Q E  R S
Sbjct: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERAS 252



 Score = 38.1 bits (87), Expect = 0.058
 Identities = 57/295 (19%), Positives = 110/295 (37%), Gaps = 24/295 (8%)

Query: 331 KKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEM 390
           K  D+H +  R       TE +    R   +   E   +  ++   E      +    E 
Sbjct: 200 KTEDRHSERGRERERERETETETERKRQTDR---ERDRQRKTEREREKQAERERASERET 256

Query: 391 QKIKSQLKEQDQ-----KWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSK 445
           ++ K + +E+D+     + Q +  +  DR++   ++  ++ E + E +++   + +R+ K
Sbjct: 257 ERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRK 316

Query: 446 TFKEMLQDRESQNQKSTVPSR------RRMYSFDDVLEEGKRPPTMTVSEASYQSERVEE 499
             +E  ++RE + Q+ T   R      +R    +   E  ++       +A  + ER  E
Sbjct: 317 RERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERE 376

Query: 500 KG--ATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQ--SPASLSSLRSRSTQMES 555
           +   +    E  + D     ++E    TE     Q   E+Q        S R R    E 
Sbjct: 377 RDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRER 436

Query: 556 TRVSASLPRSYRKTD------TVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWK 604
            +         R+TD        R T  V P P  +++  + S P   T    WK
Sbjct: 437 EKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWK 491



 Score = 36.2 bits (82), Expect = 0.22
 Identities = 44/197 (22%), Positives = 78/197 (39%), Gaps = 14/197 (7%)

Query: 329 RKKKPDKHEDNRRSWASPVYTEADGTFSR-LFQKIYGENGSKSMSDVSAEDVQNLRQLRY 387
           R +K ++  +  R       TE D    R   +K   E   +       E  +   + R 
Sbjct: 313 RNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERE 372

Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447
            E ++ +   +E++++ +D   + +DR+K      +K ++ + E EKQ   +  R S+  
Sbjct: 373 RERERDRQSAREREERERD---RDRDRQKERERQTEKDRDGQRETEKQREREKDRESERG 429

Query: 448 KEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGK-----RPPTMTVSEASYQSE-RVEEKG 501
           +E  + RE + QK     R R        +  +      PP  T      QS+     +G
Sbjct: 430 RE--RGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRG 487

Query: 502 ATYPS--EIPKEDSTTF 516
             + S  E PK  ST F
Sbjct: 488 IRWKSSPEDPKAASTRF 504



 Score = 33.9 bits (76), Expect = 1.1
 Identities = 41/181 (22%), Positives = 77/181 (42%), Gaps = 12/181 (6%)

Query: 969  WSEGSKSSDREGTRAGEEE--RRQPQEEVVHEDQGKKPQDQLVIERERKWE-QQLQEEQE 1025
            W E +   D    R G +E  RR+   +   +  G   +     ERER+ E +Q + E +
Sbjct: 17   WVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETD 76

Query: 1026 QKRLQAEAEEQKRPAE---EQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPG 1082
            +KR +   +++ R  +   E++R  E ERE      + R+     +  K  E  +    G
Sbjct: 77   RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETE-REG 135

Query: 1083 DRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRK 1142
            +R + R T    +    ++   +   Q     + + R ++ +     E ER++  QE R+
Sbjct: 136  ERGRDRQTDGQRERERQRDAEKERERQ-----TDRERQRQTERNRQKEREREKNRQERRE 190

Query: 1143 R 1143
            R
Sbjct: 191  R 191



 Score = 33.5 bits (75), Expect = 1.4
 Identities = 30/172 (17%), Positives = 74/172 (43%), Gaps = 20/172 (11%)

Query: 386 RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSK 445
           R  + +K +++ KE++++ + +  + +DR+     + +++++  +E E+Q   + +R ++
Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172

Query: 446 TFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYP 505
             ++  ++RE   Q+     R+R                    + +   +R  E+G    
Sbjct: 173 RNRQKEREREKNRQERRERERQR-------------------EKENKTEDRHSERGRERE 213

Query: 506 SEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTR 557
            E   E  T   ++ DR   + Q  ++   E+Q+    +S R      E  R
Sbjct: 214 RERETETETERKRQTDR-ERDRQRKTEREREKQAERERASERETERDKERER 264


>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
            theta, 150/170kDa [Homo sapiens]
          Length = 1382

 Score = 62.8 bits (151), Expect = 2e-09
 Identities = 87/415 (20%), Positives = 162/415 (39%), Gaps = 62/415 (14%)

Query: 824  ESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTI 883
            E L    I +K++  +  E    + +      LKN +++  +FE+      +P +     
Sbjct: 662  EELDPDFIMAKQVEQLEKEKKELQER------LKNQEKKIDYFERAKRLEEIPLIKSAY- 714

Query: 884  SAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDE 943
                     +E+  K  + W+++++  +    Q E+EK  E   R  +  E       D 
Sbjct: 715  ---------EEQRIKDMDLWEQQEEERITTM-QLEREKALEHKNRMSRMLE-------DR 757

Query: 944  ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003
            +L V+   +   +  E  L  +E   +E   +   E  R  +EERR        E++ ++
Sbjct: 758  DLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRR 817

Query: 1004 PQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP 1063
             ++Q++ ERE +   +  + +E+ R   E  ++    E +KRQ E+E E   R  +  R 
Sbjct: 818  AEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERR 877

Query: 1064 VDSYDIPKTEEASSGFLPGDRNKS---RSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRS 1120
            +    + + +        GDR+     R   E D  S  + G  +   + G      R  
Sbjct: 878  LGDSSLSRKDSRW-----GDRDSEGTWRKGPEAD--SEWRRGPPEKEWRRGEGRDEDRSH 930

Query: 1121 KKEQVPSGAELERQQILQEMRKRTP-LHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDN 1179
            ++++       ER + L +   R P L  D+  + +R    ++ P       RRG   D 
Sbjct: 931  RRDE-------ERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGP-------RRGPEEDR 976

Query: 1180 LDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPP 1234
              S R     +P W N            D  R PP+ ++  +R   R+     PP
Sbjct: 977  F-SRRGADDDRPSWRN-----------TDDDR-PPRRIADEDRGNWRHADDDRPP 1018



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 63/302 (20%), Positives = 122/302 (40%), Gaps = 94/302 (31%)

Query: 894  EEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAK----------------------- 930
            EEER RQE  ++E++R+LQE  Q +++ +RE  ++ K                       
Sbjct: 608  EEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPD 667

Query: 931  -----------------QEAERENSKYLD--------EELMVLSSNSMSLTTREPSLATW 965
                             QE  +   K +D        EE+ ++ S       ++  L  W
Sbjct: 668  FIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDL--W 725

Query: 966  EATWSEGSKSSDREGTRAGEEERRQPQ---------------EEVVHEDQGKKPQDQLVI 1010
            E    E   +   E  +A E + R  +                + V+E++ K+ +++L  
Sbjct: 726  EQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAE 785

Query: 1011 ERERKWEQQLQEEQEQKRL----QAEAEEQKR-------PAEEQKRQAEIERETSVRIYQ 1059
            ER  + E++ ++ +E++R+    + E EEQ+R         EE++R    +RE  +R YQ
Sbjct: 786  ERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQ 845

Query: 1060 YRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRR 1119
             R       + K EE        +R K +   E+++    +    +    +G+ + S++ 
Sbjct: 846  ER-------VKKLEEV-------ERKKRQRELEIEERERRREEERR----LGDSSLSRKD 887

Query: 1120 SK 1121
            S+
Sbjct: 888  SR 889



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 43/200 (21%), Positives = 85/200 (42%), Gaps = 17/200 (8%)

Query: 886  PSRWVWDQEEERKRQERW--QKEQDRLLQEKYQREQEKLREEWQRAKQ----EAERENSK 939
            P  W   +E+E+ R+E W   +E     + ++ RE+E+ R+   R +     E ER+  +
Sbjct: 1175 PGGW---REKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRER 1231

Query: 940  YLDEELMVLSSNSMSLTTREPSLATWEATWSEGSK--SSDREGTRAGEEERRQPQEEVVH 997
             +D E             R P  A   ++W + S+    DR+  R   ++RR  +E    
Sbjct: 1232 DVDREDRFRRPRDEGGWRRGP--AEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDL 1289

Query: 998  EDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRP----AEEQKRQAEIERET 1053
             D   +    L  ERE     +  ++++  R++     ++ P    + +++R  + ERE 
Sbjct: 1290 RDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREG 1349

Query: 1054 SVRIYQYRRPVDSYDIPKTE 1073
                  +R   D   + +T+
Sbjct: 1350 EKEKASWRAEKDRESLRRTK 1369



 Score = 30.8 bits (68), Expect = 9.2
 Identities = 28/135 (20%), Positives = 57/135 (42%), Gaps = 18/135 (13%)

Query: 383 RQLRYEE-MQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSK 441
           RQ  YEE +++ + +L E+     ++  + +   +  T   +K++EE+   E+Q      
Sbjct: 768 RQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQ------ 821

Query: 442 RSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDD---VLEEGKRPPTMTVSEASYQSERVE 498
                   ML++RE + +         +  + +    LEE +R       E   +  R E
Sbjct: 822 --------MLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRRE 873

Query: 499 EKGATYPSEIPKEDS 513
           E+     S + ++DS
Sbjct: 874 EERRLGDSSLSRKDS 888


>gi|4502923 calponin 3 [Homo sapiens]
          Length = 329

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 29/73 (39%), Positives = 46/73 (63%)

Query: 86  DFRASLENGVLLCDLINKLKPGVIKKINRLSTPIAGLDNINVFLKACEQIGLKEAQLFHP 145
           +F+  L++G++LC+LINKL+PG +KK+N  S     L+NI  F+KA +  G+K   +F  
Sbjct: 47  NFQLGLKDGIILCELINKLQPGSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEA 106

Query: 146 GDLQDLSNRVTVK 158
            DL +  N   V+
Sbjct: 107 NDLFENGNMTQVQ 119


>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
            [Homo sapiens]
          Length = 914

 Score = 62.4 bits (150), Expect = 3e-09
 Identities = 147/730 (20%), Positives = 274/730 (37%), Gaps = 124/730 (16%)

Query: 412  KDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYS 471
            K RR SY  D     E R+ I ++   +  RSS+     L+ ++S  + +TV        
Sbjct: 67   KKRRISYVQD-----ENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATV-------- 113

Query: 472  FDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLP- 530
               V E G     +T + A+  +  +       PS    E  T   K+ +   T+ QL  
Sbjct: 114  ---VGENGSVLRRVTRAAAAAAAATM---ALAAPSSPTPESPTMLTKKPEDNHTQCQLVP 167

Query: 531  ------SQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSY----------------RK 568
                  S+    EQ    L S       +  T  SA+ P S                 R 
Sbjct: 168  VVEIGISERQNAEQHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARI 227

Query: 569  TDTVRLTSVV-TPRPFGSQTRG------------ISSLPRSYTM--DDAWKYN------- 606
             +++ ++S++ TP+    Q  G            +S  PR      D  W+         
Sbjct: 228  LESITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILP 287

Query: 607  -------GDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPF 659
                   G   D +   ++ ++  +PSP        L+ +  + A +E V R  S     
Sbjct: 288  DNFSTPTGSRTDSQSVRHSPIAPSSPSPQV------LAQKYSLVAKQESVVRRASRRLA- 340

Query: 660  SSLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSL 719
               +++ AA+ +    S     L  E  +   S Q+E     +  +     + +  G + 
Sbjct: 341  KKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNS 400

Query: 720  --DFGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKA 777
                   I    P    A+    +P+   Q    D+         S    + +++A+++ 
Sbjct: 401  WPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSEL 460

Query: 778  QETGHLVMDVRRYGKAGSPETKWIDAT------SGIYNSEKSSNLSVTTDFSESLQSSNI 831
             E  HL  +  +  ++ +P +    +       + ++  +++  L   T    S+  S I
Sbjct: 461  DEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFI 520

Query: 832  ESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPD----LPVPTISAPS 887
            +        +     + K  E   L+NL+R+ +  EQ     V  D    L    +    
Sbjct: 521  K-------RNTPLRMDPKEKERQRLENLRRKEEA-EQLRRQKVEEDKRRRLEEVKLKREE 572

Query: 888  RW---------VWDQEEERKRQ---------ERWQK-EQDRLLQEKYQREQ--EKLREEW 926
            R          V   +EE+K+Q         E+ +K +++RL +EK +++   +K+ E  
Sbjct: 573  RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 632

Query: 927  QRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEE 986
             R KQE E    ++L +E        +    +E               +  RE  R  +E
Sbjct: 633  ARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE 692

Query: 987  ERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQ-LQEEQE----QKRLQAEAEEQKRPAE 1041
             R Q + E    +Q ++ Q++ + E+ER+ EQ+ LQ E+E    +K L+ + E+ +R  E
Sbjct: 693  RREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELE 752

Query: 1042 EQKRQAEIER 1051
            E+K++ E +R
Sbjct: 753  EKKKKEEQQR 762



 Score = 60.5 bits (145), Expect = 1e-08
 Identities = 54/192 (28%), Positives = 94/192 (48%), Gaps = 23/192 (11%)

Query: 893  QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNS 952
            +E E+ R+++ ++++ R L+E   + +E+LR+  Q  ++  + +  K    E      + 
Sbjct: 545  EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDE 604

Query: 953  MSLTTREPSLATWEATWSEGSKSSDR-EGTRAGEEERR------QPQEEVVHED--QGKK 1003
             +   +E  LA  +A     +K  +  E  R  EEE R      Q +EE  H++  Q KK
Sbjct: 605  KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKK 664

Query: 1004 PQDQ-----------LVIERE---RKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEI 1049
             ++Q           L  +RE   R+ E++ QE +EQ+R + E  EQ+R   EQ+R+ E 
Sbjct: 665  EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 724

Query: 1050 ERETSVRIYQYR 1061
            ER  + R  Q R
Sbjct: 725  ERLQAERELQER 736



 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 45/148 (30%), Positives = 75/148 (50%), Gaps = 17/148 (11%)

Query: 888  RWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAK----QEAERENSKYLDE 943
            RW+  +EEER+ QE        LLQ+K + EQE+LR+  +  +    +E ER   +  ++
Sbjct: 645  RWLQQEEEERRHQE--------LLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQ 696

Query: 944  ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003
            E             +E  LA  E    +    ++RE  +  E+  R  +E++  E + KK
Sbjct: 697  ERREQERREQERREQERQLAEQERRREQERLQAERE-LQEREKALRLQKEQLQRELEEKK 755

Query: 1004 PQDQLVIERERKWEQQLQEEQEQKRLQA 1031
             ++    E++R  E+QLQEEQE+K  +A
Sbjct: 756  KKE----EQQRLAERQLQEEQEKKAKEA 779



 Score = 41.6 bits (96), Expect = 0.005
 Identities = 37/181 (20%), Positives = 86/181 (47%), Gaps = 10/181 (5%)

Query: 360 QKIYGENGSKSMSDVSA-----EDVQNLRQLRYEEMQKIKSQ-LKEQDQKWQDDLAKWKD 413
           +K   +  +K M +V A     E+ + LR L+ EE ++   + L+++ ++ Q+ L K  +
Sbjct: 617 EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAE 676

Query: 414 -RRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSF 472
            +R +   + +++++ER E E++  E+ ++  +  +  L ++E + ++  + + R +   
Sbjct: 677 AKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQER 736

Query: 473 DDVLEEGKRPPTMTVSEASYQSE--RVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLP 530
           +  L   K      + E   + E  R+ E+      E  K      A +   VT ++Q P
Sbjct: 737 EKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE-KKAKEAAGASKALNVTVDVQSP 795

Query: 531 S 531
           +
Sbjct: 796 A 796



 Score = 36.6 bits (83), Expect = 0.17
 Identities = 30/169 (17%), Positives = 76/169 (44%), Gaps = 1/169 (0%)

Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447
           ++M++++++ K++++  +    + ++  + +   LQKKKEE +E  ++A E  + + +  
Sbjct: 626 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQRE 685

Query: 448 KEML-QDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPS 506
           +E   Q+R  Q ++      +     +  L E +R       +A  + +  E+       
Sbjct: 686 QERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKE 745

Query: 507 EIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMES 555
           ++ +E      K E +   E QL  +   + +  A  S   + +  ++S
Sbjct: 746 QLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQS 794



 Score = 36.2 bits (82), Expect = 0.22
 Identities = 32/135 (23%), Positives = 61/135 (45%), Gaps = 6/135 (4%)

Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1070
            ER+R    + +EE EQ R Q   E+++R  EE K + E   E   ++ Q R  V+     
Sbjct: 534  ERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE---ERLRKVLQARERVEQMKEE 590

Query: 1071 KTEEASSGFLPGDRNKSRSTTE-LDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGA 1129
            K ++    F   D    ++  E L +    K    K ++++      +  +++ +     
Sbjct: 591  KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 650

Query: 1130 ELER--QQILQEMRK 1142
            E ER  Q++LQ+ ++
Sbjct: 651  EEERRHQELLQKKKE 665



 Score = 32.0 bits (71), Expect = 4.1
 Identities = 39/227 (17%), Positives = 100/227 (44%), Gaps = 37/227 (16%)

Query: 365 ENGSKSMSDVSAEDVQNLRQL-----RYEEMQKIK--------SQLKEQDQKWQDD-LAK 410
           E+  + + +V  +  + LR++     R E+M++ K        +Q+ E+ +K +++ LA+
Sbjct: 557 EDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAE 616

Query: 411 WKDRRKSYT---SDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRR 467
            K ++K+      +++ ++++ EE  +    + +   +  +E+LQ ++ + Q+     R 
Sbjct: 617 EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQE-----RL 671

Query: 468 RMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEI 527
           R  +      E KR       E   Q  R +E+      E  + +       ++R   + 
Sbjct: 672 RKAA------EAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQE 725

Query: 528 QLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRL 574
           +L ++  ++E         R ++ +++  ++   L    +K +  RL
Sbjct: 726 RLQAERELQE---------REKALRLQKEQLQRELEEKKKKEEQQRL 763


>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
          Length = 1293

 Score = 61.6 bits (148), Expect = 5e-09
 Identities = 55/213 (25%), Positives = 91/213 (42%), Gaps = 31/213 (14%)

Query: 881  PTISAPSRW----VWD----------------QEEERK----RQERWQKEQDRLLQEKYQ 916
            PT S P+ W    VWD                Q E+ K     QER + E     +E+ +
Sbjct: 690  PTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEER 749

Query: 917  REQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSS 976
            + QE+LR + +   +  + E  K  +EE +       +L  +            E  +  
Sbjct: 750  KRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQ 809

Query: 977  DREGTRAGEEERRQPQEEVVHEDQGKKPQDQLV------IERERKWEQ-QLQEEQEQKRL 1029
              E  R  EE RR+ +E    E+  +K +++         E +R+ E+ +L+ E+E  RL
Sbjct: 810  QEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARL 869

Query: 1030 QAEAEEQKRPAEEQKRQAEIERETSVRIYQYRR 1062
            + E EE+KR   E +RQ E+ R+   +    RR
Sbjct: 870  RHEEEERKRKELEVQRQKELMRQRQQQQEALRR 902



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 69/335 (20%), Positives = 143/335 (42%), Gaps = 32/335 (9%)

Query: 893  QEEERKRQERWQKEQDRLL-----QEKYQREQEKL------------REEWQRAKQEAER 935
            +EEERKRQE  +++Q+ +L     +E+ +RE+E+L            RE+    +++ E 
Sbjct: 745  EEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREE 804

Query: 936  ENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSK--SSDREGTRAGEEERRQPQE 993
            E  +  +E L  L         R            E +K    + E  R  EE R + +E
Sbjct: 805  EERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE 864

Query: 994  EVV---HEDQGKKPQDQLVIERERKWEQQLQEEQEQ-KRLQAEAEEQKRPAEEQKRQAEI 1049
            E     HE++ +K + +L ++R+++  +Q Q++QE  +RLQ + ++Q+    +    +  
Sbjct: 865  EAARLRHEEEERK-RKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTW 923

Query: 1050 ERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQ 1109
             ++++    Q +  +   +I K EE     L  ++ + +    +      +    + L  
Sbjct: 924  GQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSG 982

Query: 1110 IGNMTSSQRRSK---KEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVS 1166
             GN++     +K   + Q     ++++QQ  Q+  ++     +N+     ++  N    S
Sbjct: 983  WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGN----S 1038

Query: 1167 LPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFY 1201
            + G +  G          S+ W      N   GF+
Sbjct: 1039 VWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFW 1073



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 58/272 (21%), Positives = 115/272 (42%), Gaps = 35/272 (12%)

Query: 887  SRWVWDQEEERKRQE----RWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLD 942
            ++W  ++EE ++R E    R ++E  RL  E+ +R++++L  + Q+      ++  + L 
Sbjct: 842  AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL- 900

Query: 943  EELMVLSSNSMSLTTREPSLATW-----------EATWS--EGSKSSDREGTRAGEEERR 989
              L            + PS +TW           +AT S  E  K  +    +  EE+RR
Sbjct: 901  RRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 960

Query: 990  QPQEEVVHEDQGKKPQDQLV-----IERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQK 1044
            Q +E +    Q ++ Q Q +     + +     + L E Q+++  Q + ++Q++   +Q 
Sbjct: 961  QQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQP 1020

Query: 1045 RQAEIERETSVRIYQYRRPVDSYDI-PKTEEAS---SGFLPGDRNKSRSTTELDD----- 1095
             +A     +++          S +  P  + AS   S        K+ +    DD     
Sbjct: 1021 NRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEV 1080

Query: 1096 ---YSTNKNGNNKYLDQIGNMTSSQRRSKKEQ 1124
                STNKN NN  L +   +++ Q +  +E+
Sbjct: 1081 GPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1112



 Score = 34.7 bits (78), Expect = 0.64
 Identities = 37/200 (18%), Positives = 83/200 (41%), Gaps = 22/200 (11%)

Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEE------------REEIE-- 433
           ++++K K+   EQ+++  +  AK ++  +    +L++++EE            REE E  
Sbjct: 721 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 780

Query: 434 ----KQALEKSKRSSKTFKEMLQDRESQNQKST---VPSRRRMYSFDDVLEEGKRPPTMT 486
               ++AL + +      +   ++ E Q Q+     +  RRR        EE  R     
Sbjct: 781 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 840

Query: 487 VSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSL 546
            ++ + + E  + +       + +E +    + E+R   E+++  Q  +  Q      +L
Sbjct: 841 AAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL 900

Query: 547 RSRSTQMESTRVS-ASLPRS 565
           R    Q +  +++   LP S
Sbjct: 901 RRLQQQQQQQQLAQMKLPSS 920



 Score = 32.7 bits (73), Expect = 2.4
 Identities = 21/82 (25%), Positives = 43/82 (52%), Gaps = 6/82 (7%)

Query: 382 LRQLRYEEMQKIKSQLK-EQDQKW--QDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALE 438
           LR+L+ ++ Q+  +Q+K      W  Q +    + +     +++QK +EER   E+Q  E
Sbjct: 900 LRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER---ERQLRE 956

Query: 439 KSKRSSKTFKEMLQDRESQNQK 460
           + +R  +   + LQ ++ Q Q+
Sbjct: 957 EQRRQQRELMKALQQQQQQQQQ 978


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.311    0.126    0.360 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 54,105,566
Number of Sequences: 37866
Number of extensions: 2739905
Number of successful extensions: 39832
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 353
Number of HSP's successfully gapped in prelim test: 1222
Number of HSP's that attempted gapping in prelim test: 17003
Number of HSP's gapped (non-prelim): 11068
length of query: 1349
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1235
effective length of database: 13,930,794
effective search space: 17204530590
effective search space used: 17204530590
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.8 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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