BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] (1349 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] 2694 0.0 gi|221316634 LIM domain only 7 isoform 2 [Homo sapiens] 1805 0.0 gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 451 e-126 gi|163310743 LIM and calponin homology domains 1 isoform b [Homo... 442 e-123 gi|163310741 LIM and calponin homology domains 1 isoform a [Homo... 442 e-123 gi|163310747 LIM and calponin homology domains 1 isoform d [Homo... 290 5e-78 gi|163310749 LIM and calponin homology domains 1 isoform e [Homo... 289 1e-77 gi|148746195 trichohyalin [Homo sapiens] 80 1e-14 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 77 9e-14 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 75 3e-13 gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 74 9e-13 gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 74 9e-13 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 74 1e-12 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 73 2e-12 gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 69 2e-11 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 69 2e-11 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 67 9e-11 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 67 1e-10 gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 67 2e-10 gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 66 3e-10 gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 66 3e-10 gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 65 3e-10 gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 65 3e-10 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 65 4e-10 gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 64 8e-10 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 64 1e-09 gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 63 2e-09 gi|4502923 calponin 3 [Homo sapiens] 62 3e-09 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 62 3e-09 gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 62 5e-09 >gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] Length = 1349 Score = 2694 bits (6982), Expect = 0.0 Identities = 1349/1349 (100%), Positives = 1349/1349 (100%) Query: 1 MKKIRICHIFTFYSWMSYDVLFQRTELGALEIWRQLICAHVCICVGWLYLRDRVCSKKDI 60 MKKIRICHIFTFYSWMSYDVLFQRTELGALEIWRQLICAHVCICVGWLYLRDRVCSKKDI Sbjct: 1 MKKIRICHIFTFYSWMSYDVLFQRTELGALEIWRQLICAHVCICVGWLYLRDRVCSKKDI 60 Query: 61 ILRTEQNSGRTILIKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIA 120 ILRTEQNSGRTILIKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIA Sbjct: 61 ILRTEQNSGRTILIKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIA 120 Query: 121 GLDNINVFLKACEQIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKA 180 GLDNINVFLKACEQIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKA Sbjct: 121 GLDNINVFLKACEQIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKA 180 Query: 181 QSNPYYNGPHLNLKAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRH 240 QSNPYYNGPHLNLKAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRH Sbjct: 181 QSNPYYNGPHLNLKAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRH 240 Query: 241 HKREDSFESLDSLGSRSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRIS 300 HKREDSFESLDSLGSRSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRIS Sbjct: 241 HKREDSFESLDSLGSRSLTSCSSDITLRGGREGFESDTDSEFTFKMQDYNKDDMSYRRIS 300 Query: 301 AVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQ 360 AVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQ Sbjct: 301 AVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQ 360 Query: 361 KIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTS 420 KIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTS Sbjct: 361 KIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTS 420 Query: 421 DLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGK 480 DLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGK Sbjct: 421 DLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGK 480 Query: 481 RPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSP 540 RPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSP Sbjct: 481 RPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSP 540 Query: 541 ASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMD 600 ASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMD Sbjct: 541 ASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMD 600 Query: 601 DAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFS 660 DAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFS Sbjct: 601 DAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFS 660 Query: 661 SLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLD 720 SLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLD Sbjct: 661 SLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLD 720 Query: 721 FGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQET 780 FGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQET Sbjct: 721 FGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQET 780 Query: 781 GHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIH 840 GHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIH Sbjct: 781 GHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIH 840 Query: 841 DESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQ 900 DESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQ Sbjct: 841 DESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQ 900 Query: 901 ERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREP 960 ERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREP Sbjct: 901 ERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREP 960 Query: 961 SLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQL 1020 SLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQL Sbjct: 961 SLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQL 1020 Query: 1021 QEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFL 1080 QEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFL Sbjct: 1021 QEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFL 1080 Query: 1081 PGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEM 1140 PGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEM Sbjct: 1081 PGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEM 1140 Query: 1141 RKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGF 1200 RKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGF Sbjct: 1141 RKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGF 1200 Query: 1201 YASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSP 1260 YASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSP Sbjct: 1201 YASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSP 1260 Query: 1261 SASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSS 1320 SASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSS Sbjct: 1261 SASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCFKCVACECDLGGSS 1320 Query: 1321 SGAEVRIRNHQLYCNDCYLRFKSGRPTAM 1349 SGAEVRIRNHQLYCNDCYLRFKSGRPTAM Sbjct: 1321 SGAEVRIRNHQLYCNDCYLRFKSGRPTAM 1349 >gi|221316634 LIM domain only 7 isoform 2 [Homo sapiens] Length = 1385 Score = 1805 bits (4676), Expect = 0.0 Identities = 930/981 (94%), Positives = 939/981 (95%), Gaps = 12/981 (1%) Query: 291 KDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTE 350 KDDM R+I + + T +P S+ P P + + E R AS + + Sbjct: 352 KDDMLTRKIQSWKLGTTVP----------PISFTPGPCSEADLKRWEAIRE--ASRLRHK 399 Query: 351 ADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK 410 RLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK Sbjct: 400 KRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK 459 Query: 411 WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMY 470 WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMY Sbjct: 460 WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMY 519 Query: 471 SFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLP 530 SFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLP Sbjct: 520 SFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLP 579 Query: 531 SQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGI 590 SQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGI Sbjct: 580 SQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGI 639 Query: 591 SSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVT 650 SSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVT Sbjct: 640 SSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVT 699 Query: 651 RLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRIS 710 RLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRIS Sbjct: 700 RLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRIS 759 Query: 711 INQTPGKSLDFGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEW 770 INQTPGKSLDFGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEW Sbjct: 760 INQTPGKSLDFGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEW 819 Query: 771 EEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSN 830 EEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSN Sbjct: 820 EEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSN 879 Query: 831 IESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWV 890 IESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWV Sbjct: 880 IESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWV 939 Query: 891 WDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS 950 WDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS Sbjct: 940 WDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS 999 Query: 951 NSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVI 1010 NSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVI Sbjct: 1000 NSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVI 1059 Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1070 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP Sbjct: 1060 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1119 Query: 1071 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAE 1130 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAE Sbjct: 1120 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAE 1179 Query: 1131 LERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQ 1190 LERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQ Sbjct: 1180 LERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQ 1239 Query: 1191 PPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATT 1250 PPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATT Sbjct: 1240 PPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATT 1299 Query: 1251 QSPTPRSHSPSASQSGSQLRN 1271 QSPTPRSHSPSASQSGSQLRN Sbjct: 1300 QSPTPRSHSPSASQSGSQLRN 1320 Score = 157 bits (396), Expect = 9e-38 Identities = 74/81 (91%), Positives = 77/81 (95%) Query: 286 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 345 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS Sbjct: 1 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 60 Query: 346 PVYTEADGTFSRLFQKIYGEN 366 PVYTEADGTFS ++I+G N Sbjct: 61 PVYTEADGTFSSNQRRIWGTN 81 >gi|163310745 LIM and calponin homology domains 1 isoform c [Homo sapiens] Length = 1056 Score = 451 bits (1160), Expect = e-126 Identities = 329/984 (33%), Positives = 507/984 (51%), Gaps = 144/984 (14%) Query: 74 IKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIAGLDNINVFLKACE 133 I+ VT ++F KDFR LENG+LLC+L+N +KPG++KKINRL TPIAGLDNI +FL+ C+ Sbjct: 31 IEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCK 90 Query: 134 QIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKAQSNPYYNGPHLNL 193 ++GLKE+QLF P DLQD SNRVTVK + R++KNVL+T+YWLG+ A S Y+G LNL Sbjct: 91 ELGLKESQLFDPSDLQDTSNRVTVKSLDYSRKLKNVLVTIYWLGKAANSCTSYSGTTLNL 150 Query: 194 KAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRHHKREDSFESLDSL 253 K FE LL Q + K +D KRS RDSGY D W ER + L+PPR H R+DSF+SLDS Sbjct: 151 KEFEGLLAQ-MRKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPR-HGRDDSFDSLDSF 208 Query: 254 GSRSLTSCSSDITLRGGREGFESDTDSEFTF-KMQDYNKDDMSYRRISAVEPKTALPFNR 312 GSRS + S D+ LRG +G SD++S+ K+ D KDDMS RR S EPK+A+PFN+ Sbjct: 209 GSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQ 268 Query: 313 FLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWA---SPVYTEADGTFSRLFQKIYGENGSK 369 +LPNKS Q +YVPAPLRKKK ++ E+ R+SW+ SP+ E + + + S Sbjct: 269 YLPNKSNQTAYVPAPLRKKKAER-EEYRKSWSTATSPLGGERPFRYGPR-TPVSDDAEST 326 Query: 370 SMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKK 426 SM D+ E+ VQ + R E++Q I +QL+E+D KWQDDLA+WK RR+S + DL KK+ Sbjct: 327 SMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKE 386 Query: 427 EEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK--STVPSRRRMYSFDDVLEEG 479 EER+++EK + ++S KT++E++Q++E + ++ + R + +L++ Sbjct: 387 EERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ- 445 Query: 480 KRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQS 539 T+SEA ER+E S + + ++F + + L QS + Sbjct: 446 -YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLNDPNPMK---YLRQQSLPPPKF 499 Query: 540 PASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTM 599 A++ + +R++ ++++ + S S KT T + ++TP+P+ SQ + + +++ + Sbjct: 500 TATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPMLTPKPY-SQPKNSQDVLKTFKV 556 Query: 600 DDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPF 659 D NG E EE+ R +P Sbjct: 557 DGKVSVNG---------------------------------ETVHREEEKERECPTVAPA 583 Query: 660 SSLSQDQAATSKATLSSTSGLDLMSESGEGEI------SPQREVSRSQDQFSDMRISINQ 713 SL++ Q A + S L+L ++G EI S +E++ + ++ Sbjct: 584 HSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKN 642 Query: 714 TPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVDDEIIAINNTKFSYNDSKEWEE 772 GKS + P F +V SP F + + + N D K+ E Sbjct: 643 DGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQ---LKNDVSEEKDQKKPEN 699 Query: 773 AMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIE 832 M+ E LV+ ++ K SPE + ++T F + + +N Sbjct: 700 EMSGKVE---LVLS-QKVVKPKSPEPE----------------ATLTFPFLDKMPEAN-- 737 Query: 833 SKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWD 892 + L NL SQ S S P ++ W WD Sbjct: 738 --------------------QLHLPNL--NSQVDSPSSEKS-------PVMTPFKFWAWD 768 Query: 893 QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNS 952 EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A++E E E +Y +EE ++ Sbjct: 769 PEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTV 828 Query: 953 MSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIER 1012 + T S S+D+ T + E ++ D G QD+ ++ Sbjct: 829 VPFTV--------------SSSSADQLSTSSSMTEGSGTMNKI---DLG-NCQDE---KQ 867 Query: 1013 ERKWEQQLQEEQEQKRLQAEAEEQ 1036 +R+W++ Q + L+ ++ Sbjct: 868 DRRWKKSFQGDDSDLLLKTRESDR 891 Score = 113 bits (282), Expect = 1e-24 Identities = 101/343 (29%), Positives = 160/343 (46%), Gaps = 60/343 (17%) Query: 1011 ERERKWEQQLQEEQE---QKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSY 1067 E ER+ +++ Q+EQE Q+R Q E ++ K E +K Q E+E E + R+ ++ Sbjct: 770 EEERRRQEKWQQEQERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDT 827 Query: 1068 DIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPS 1127 +P T +SS D+ + S+ T +G +D +GN Sbjct: 828 VVPFTVSSSS----ADQLSTSSS------MTEGSGTMNKID-LGNC-------------- 862 Query: 1128 GAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNS 1187 Q Q+ R + D+S + ++ ++ + G + G +L + +P S Sbjct: 863 ------QDEKQDRRWKKSFQGDDSDLLLKTRESDR--LEEKGSLTEG-ALAHSGNPVSKG 913 Query: 1188 WRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGV 1247 + L+ G + ++ P Q TSN P S+ VK T + Sbjct: 914 VHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN-----------PTHSSEDVKPKT--L 960 Query: 1248 ATTQSPTPRSHSPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCF 1307 +S + SPS R +S+SGK++CS C LGKGAAMIIE+L L +H+ CF Sbjct: 961 PLDKSINHQIESPSE-------RRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCF 1013 Query: 1308 KCVACECDLGGSSSGAEVRIRNHQLYCNDCYLRFKS-GRPTAM 1349 +C C+ LG + SG +VRIRN L CNDCY+R +S G+PT + Sbjct: 1014 RCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1056 Score = 31.6 bits (70), Expect = 5.4 Identities = 58/271 (21%), Positives = 102/271 (37%), Gaps = 39/271 (14%) Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1070 E ++ + +EE + +EQ + Q R+ + + + + ++ RR S D+ Sbjct: 324 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 383 Query: 1071 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1129 K EE +R K +D ++ + + K +I + R E + + Sbjct: 384 KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 435 Query: 1130 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1188 + E + ILQ+ +R + + E + +P I+ R S + NL S Sbjct: 436 QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 478 Query: 1189 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1246 +LN P ++ S PPP+ +T R +S+ S KT T Sbjct: 479 ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 531 Query: 1247 VATTQSPTPRSHSPSASQSGSQLRNRSVSGK 1277 +P P S P SQ L+ V GK Sbjct: 532 AVPMLTPKPYS-QPKNSQ--DVLKTFKVDGK 559 >gi|163310743 LIM and calponin homology domains 1 isoform b [Homo sapiens] Length = 1057 Score = 442 bits (1137), Expect = e-123 Identities = 331/986 (33%), Positives = 507/986 (51%), Gaps = 147/986 (14%) Query: 74 IKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIAGLDNINVFLKACE 133 I+ VT ++F KDFR LENG+LLC+L+N +KPG++KKINRL TPIAGLDNI +FL+ C+ Sbjct: 31 IEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCK 90 Query: 134 QIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKAQSNPYYNGPHLNL 193 ++GLKE+QLF P DLQD SNRVTVK + R++KNVL+T+YWLG+ A S Y+G LNL Sbjct: 91 ELGLKESQLFDPSDLQDTSNRVTVKSLDYSRKLKNVLVTIYWLGKAANSCTSYSGTTLNL 150 Query: 194 KAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRHHKREDSFESLDSL 253 K FE LL Q + K +D KRS RDSGY D W ER + L+PPR H R+DSF+SLDS Sbjct: 151 KEFEGLLAQ-MRKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPR-HGRDDSFDSLDSF 208 Query: 254 GSRSLTSCSSDITLRGGREGFESDTDSEFTF-KMQDYNKDDMSYRRISAVEPKTALPFNR 312 GSRS + S D+ LRG +G SD++S+ K+ D KDDMS RR S EPK+A+PFN+ Sbjct: 209 GSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQ 268 Query: 313 FLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWA---SPVYTEADGTFSRLFQKIYGENGSK 369 +LPNKS Q +YVPAPLRKKK ++ E+ R+SW+ SP+ E + + + S Sbjct: 269 YLPNKSNQTAYVPAPLRKKKAER-EEYRKSWSTATSPLGGERPFRYGPR-TPVSDDAEST 326 Query: 370 SMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKK 426 SM D+ E+ VQ + R E++Q I +QL+E+D KWQDDLA+WK RR+S + DL KK+ Sbjct: 327 SMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKE 386 Query: 427 EEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK--STVPSRRRMYSFDDVLEEG 479 EER+++EK + ++S KT++E++Q++E + ++ + R + +L++ Sbjct: 387 EERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ- 445 Query: 480 KRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQS 539 T+SEA ER+E S + + ++F + + L QS + Sbjct: 446 -YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLNDPNPMK---YLRQQSLPPPKF 499 Query: 540 PASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTM 599 A++ + +R++ ++++ + S S KT T + ++TP+P+ SQ + + +++ + Sbjct: 500 TATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPMLTPKPY-SQPKNSQDVLKTFKV 556 Query: 600 DDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPF 659 D NG E EE+ R +P Sbjct: 557 DGKVSVNG---------------------------------ETVHREEEKERECPTVAPA 583 Query: 660 SSLSQDQAATSKATLSSTSGLDLMSESGEGEI------SPQREVSRSQDQFSDMRISINQ 713 SL++ Q A + S L+L ++G EI S +E++ + ++ Sbjct: 584 HSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKN 642 Query: 714 TPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVDDEIIAINNTKFSYNDSKEWEE 772 GKS + P F +V SP F + + + N D K+ E Sbjct: 643 DGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQ---LKNDVSEEKDQKKPEN 699 Query: 773 AMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIE 832 M+ E LV+ ++ K SPE + ++T F + + +N Sbjct: 700 EMSGKVE---LVLS-QKVVKPKSPEPE----------------ATLTFPFLDKMPEAN-- 737 Query: 833 SKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVW- 891 + L NL SQ S S PV T P W Sbjct: 738 --------------------QLHLPNL--NSQVDSPSSEKS-----PVMT---PQFKFWA 767 Query: 892 -DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS 950 D EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A++E E E +Y +EE ++ Sbjct: 768 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 827 Query: 951 NSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVI 1010 + T S S+D+ T + E ++ D G QD+ Sbjct: 828 TVVPFTV--------------SSSSADQLSTSSSMTEGSGTMNKI---DLG-NCQDE--- 866 Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQ 1036 +++R+W++ Q + L+ ++ Sbjct: 867 KQDRRWKKSFQGDDSDLLLKTRESDR 892 Score = 113 bits (282), Expect = 1e-24 Identities = 101/343 (29%), Positives = 160/343 (46%), Gaps = 60/343 (17%) Query: 1011 ERERKWEQQLQEEQE---QKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSY 1067 E ER+ +++ Q+EQE Q+R Q E ++ K E +K Q E+E E + R+ ++ Sbjct: 771 EEERRRQEKWQQEQERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDT 828 Query: 1068 DIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPS 1127 +P T +SS D+ + S+ T +G +D +GN Sbjct: 829 VVPFTVSSSS----ADQLSTSSS------MTEGSGTMNKID-LGNC-------------- 863 Query: 1128 GAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNS 1187 Q Q+ R + D+S + ++ ++ + G + G +L + +P S Sbjct: 864 ------QDEKQDRRWKKSFQGDDSDLLLKTRESDR--LEEKGSLTEG-ALAHSGNPVSKG 914 Query: 1188 WRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGV 1247 + L+ G + ++ P Q TSN P S+ VK T + Sbjct: 915 VHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN-----------PTHSSEDVKPKT--L 961 Query: 1248 ATTQSPTPRSHSPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCF 1307 +S + SPS R +S+SGK++CS C LGKGAAMIIE+L L +H+ CF Sbjct: 962 PLDKSINHQIESPSE-------RRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCF 1014 Query: 1308 KCVACECDLGGSSSGAEVRIRNHQLYCNDCYLRFKS-GRPTAM 1349 +C C+ LG + SG +VRIRN L CNDCY+R +S G+PT + Sbjct: 1015 RCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1057 Score = 31.6 bits (70), Expect = 5.4 Identities = 58/271 (21%), Positives = 102/271 (37%), Gaps = 39/271 (14%) Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1070 E ++ + +EE + +EQ + Q R+ + + + + ++ RR S D+ Sbjct: 324 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 383 Query: 1071 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1129 K EE +R K +D ++ + + K +I + R E + + Sbjct: 384 KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 435 Query: 1130 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1188 + E + ILQ+ +R + + E + +P I+ R S + NL S Sbjct: 436 QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 478 Query: 1189 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1246 +LN P ++ S PPP+ +T R +S+ S KT T Sbjct: 479 ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 531 Query: 1247 VATTQSPTPRSHSPSASQSGSQLRNRSVSGK 1277 +P P S P SQ L+ V GK Sbjct: 532 AVPMLTPKPYS-QPKNSQ--DVLKTFKVDGK 559 >gi|163310741 LIM and calponin homology domains 1 isoform a [Homo sapiens] Length = 1083 Score = 442 bits (1137), Expect = e-123 Identities = 331/986 (33%), Positives = 507/986 (51%), Gaps = 147/986 (14%) Query: 74 IKAVTEKNFETKDFRASLENGVLLCDLINKLKPGVIKKINRLSTPIAGLDNINVFLKACE 133 I+ VT ++F KDFR LENG+LLC+L+N +KPG++KKINRL TPIAGLDNI +FL+ C+ Sbjct: 31 IEQVTGRSFGDKDFRTGLENGILLCELLNAIKPGLVKKINRLPTPIAGLDNIILFLRGCK 90 Query: 134 QIGLKEAQLFHPGDLQDLSNRVTVKQEETDRRVKNVLITLYWLGRKAQSNPYYNGPHLNL 193 ++GLKE+QLF P DLQD SNRVTVK + R++KNVL+T+YWLG+ A S Y+G LNL Sbjct: 91 ELGLKESQLFDPSDLQDTSNRVTVKSLDYSRKLKNVLVTIYWLGKAANSCTSYSGTTLNL 150 Query: 194 KAFENLLGQALTKALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRHHKREDSFESLDSL 253 K FE LL Q + K +D KRS RDSGY D W ER + L+PPR H R+DSF+SLDS Sbjct: 151 KEFEGLLAQ-MRKDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPR-HGRDDSFDSLDSF 208 Query: 254 GSRSLTSCSSDITLRGGREGFESDTDSEFTF-KMQDYNKDDMSYRRISAVEPKTALPFNR 312 GSRS + S D+ LRG +G SD++S+ K+ D KDDMS RR S EPK+A+PFN+ Sbjct: 209 GSRSRQTPSPDVVLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQ 268 Query: 313 FLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWA---SPVYTEADGTFSRLFQKIYGENGSK 369 +LPNKS Q +YVPAPLRKKK ++ E+ R+SW+ SP+ E + + + S Sbjct: 269 YLPNKSNQTAYVPAPLRKKKAER-EEYRKSWSTATSPLGGERPFRYGPR-TPVSDDAEST 326 Query: 370 SMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKK 426 SM D+ E+ VQ + R E++Q I +QL+E+D KWQDDLA+WK RR+S + DL KK+ Sbjct: 327 SMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKE 386 Query: 427 EEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK--STVPSRRRMYSFDDVLEEG 479 EER+++EK + ++S KT++E++Q++E + ++ + R + +L++ Sbjct: 387 EERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ- 445 Query: 480 KRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQS 539 T+SEA ER+E S + + ++F + + L QS + Sbjct: 446 -YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLNDPNPMK---YLRQQSLPPPKF 499 Query: 540 PASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTM 599 A++ + +R++ ++++ + S S KT T + ++TP+P+ SQ + + +++ + Sbjct: 500 TATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPMLTPKPY-SQPKNSQDVLKTFKV 556 Query: 600 DDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPF 659 D NG E EE+ R +P Sbjct: 557 DGKVSVNG---------------------------------ETVHREEEKERECPTVAPA 583 Query: 660 SSLSQDQAATSKATLSSTSGLDLMSESGEGEI------SPQREVSRSQDQFSDMRISINQ 713 SL++ Q A + S L+L ++G EI S +E++ + ++ Sbjct: 584 HSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKN 642 Query: 714 TPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVDDEIIAINNTKFSYNDSKEWEE 772 GKS + P F +V SP F + + + N D K+ E Sbjct: 643 DGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQ---LKNDVSEEKDQKKPEN 699 Query: 773 AMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIE 832 M+ E LV+ ++ K SPE + ++T F + + +N Sbjct: 700 EMSGKVE---LVLS-QKVVKPKSPEPE----------------ATLTFPFLDKMPEAN-- 737 Query: 833 SKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVW- 891 + L NL SQ S S PV T P W Sbjct: 738 --------------------QLHLPNL--NSQVDSPSSEKS-----PVMT---PQFKFWA 767 Query: 892 -DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS 950 D EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A++E E E +Y +EE ++ Sbjct: 768 WDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIED 827 Query: 951 NSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVI 1010 + T S S+D+ T + E ++ D G QD+ Sbjct: 828 TVVPFTV--------------SSSSADQLSTSSSMTEGSGTMNKI---DLG-NCQDE--- 866 Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQ 1036 +++R+W++ Q + L+ ++ Sbjct: 867 KQDRRWKKSFQGDDSDLLLKTRESDR 892 Score = 123 bits (308), Expect = 1e-27 Identities = 101/349 (28%), Positives = 161/349 (46%), Gaps = 46/349 (13%) Query: 1011 ERERKWEQQLQEEQE---QKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSY 1067 E ER+ +++ Q+EQE Q+R Q E ++ K E +K Q E+E E + R+ ++ Sbjct: 771 EEERRRQEKWQQEQERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDT 828 Query: 1068 DIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPS 1127 +P T +SS D+ + S+ T +G +D +GN Sbjct: 829 VVPFTVSSSS----ADQLSTSSS------MTEGSGTMNKID-LGNC-------------- 863 Query: 1128 GAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNS 1187 Q Q+ R + D+S + ++ ++ + G + G +L + +P S Sbjct: 864 ------QDEKQDRRWKKSFQGDDSDLLLKTRESDR--LEEKGSLTEG-ALAHSGNPVSKG 914 Query: 1188 WRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGV 1247 + L+ G + ++ P Q TSN + P S+ Sbjct: 915 VHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSNPTHSSEDVKPKTLPLDKSINHQIESP 974 Query: 1248 ATTQSPTPRSH------SPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLC 1301 + + +PR H SP + Q NRS+SGK++CS C LGKGAAMIIE+L L Sbjct: 975 SERRKKSPREHFQAGPFSPCSPTPPGQSPNRSISGKKLCSSCGLPLGKGAAMIIETLNLY 1034 Query: 1302 YHLHCFKCVACECDLGGSSSGAEVRIRNHQLYCNDCYLRFKS-GRPTAM 1349 +H+ CF+C C+ LG + SG +VRIRN L CNDCY+R +S G+PT + Sbjct: 1035 FHIQCFRCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 1083 Score = 31.6 bits (70), Expect = 5.4 Identities = 58/271 (21%), Positives = 102/271 (37%), Gaps = 39/271 (14%) Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1070 E ++ + +EE + +EQ + Q R+ + + + + ++ RR S D+ Sbjct: 324 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 383 Query: 1071 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1129 K EE +R K +D ++ + + K +I + R E + + Sbjct: 384 KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 435 Query: 1130 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1188 + E + ILQ+ +R + + E + +P I+ R S + NL S Sbjct: 436 QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 478 Query: 1189 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1246 +LN P ++ S PPP+ +T R +S+ S KT T Sbjct: 479 ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 531 Query: 1247 VATTQSPTPRSHSPSASQSGSQLRNRSVSGK 1277 +P P S P SQ L+ V GK Sbjct: 532 AVPMLTPKPYS-QPKNSQ--DVLKTFKVDGK 559 >gi|163310747 LIM and calponin homology domains 1 isoform d [Homo sapiens] Length = 902 Score = 290 bits (743), Expect = 5e-78 Identities = 249/852 (29%), Positives = 404/852 (47%), Gaps = 143/852 (16%) Query: 206 KALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRHHKREDSFESLDSLGSRSLTSCSSDI 265 K +D KRS RDSGY D W ER + L+PPRH R+DSF+SLDS GSRS + S D+ Sbjct: 8 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHG-RDDSFDSLDSFGSRSRQTPSPDV 66 Query: 266 TLRGGREGFESDTDSEFTF-KMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYV 324 LRG +G SD++S+ K+ D KDDMS RR S EPK+A+PFN++LPNKS Q +YV Sbjct: 67 VLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYV 126 Query: 325 PAPLRKKKPDKHEDNRRSWA---SPVYTEADGTFSRLFQKIYGENGSKSMSDVSAED--- 378 PAPLRKKK ++ E+ R+SW+ SP+ E + + + S SM D+ E+ Sbjct: 127 PAPLRKKKAER-EEYRKSWSTATSPLGGERPFRYGPR-TPVSDDAESTSMFDMRCEEEAA 184 Query: 379 VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEK---- 434 VQ + R E++Q I +QL+E+D KWQDDLA+WK RR+S + DL KK+EER+++EK Sbjct: 185 VQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAG 244 Query: 435 -QALEKSKRSSKTFKEMLQDRESQNQK--STVPSRRRMYSFDDVLEEGKRPPTMTVSEAS 491 + ++S KT++E++Q++E + ++ + R + +L++ T+SEA Sbjct: 245 EDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ--YIERFTISEAV 302 Query: 492 YQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRST 551 ER+E S + + ++F + + L QS + A++ + +R++ Sbjct: 303 L--ERLEMPKILERSHSTEPNLSSFLNDPNPMK---YLRQQSLPPPKFTATVETTIARAS 357 Query: 552 QMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVED 611 ++++ + S S KT T + ++TP+P+ SQ + + +++ +D NG Sbjct: 358 VLDTSMSAGS--GSPSKTVTPKAVPMLTPKPY-SQPKNSQDVLKTFKVDGKVSVNG---- 410 Query: 612 IKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSK 671 E EE+ R +P SL++ Q Sbjct: 411 -----------------------------ETVHREEEKERECPTVAPAHSLTKSQMFEGV 441 Query: 672 ATLSSTSGLDLMSESGEGEI------SPQREVSRSQDQFSDMRISINQTPGKSLDFGFTI 725 A + S L+L ++G EI S +E++ + ++ GKS + Sbjct: 442 ARVHG-SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIEL 500 Query: 726 KWDIPGIFVASVEAGSP-AEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLV 784 P F +V SP F + + + N D K+ E M+ E LV Sbjct: 501 ASSEPQHFTTTVTRCSPTVAFVEFPSSPQ---LKNDVSEEKDQKKPENEMSGKVE---LV 554 Query: 785 MDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESN 844 + ++ K SPE + ++T F + + +N Sbjct: 555 LS-QKVVKPKSPEPE----------------ATLTFPFLDKMPEAN-------------- 583 Query: 845 AFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQ 904 + L NL SQ S S P ++ W WD EEER+RQE+WQ Sbjct: 584 --------QLHLPNL--NSQVDSPSSEKS-------PVMTPFKFWAWDPEEERRRQEKWQ 626 Query: 905 KEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLAT 964 +EQ+RLLQE+YQ+EQ+KL+EEW++A++E E E +Y +EE ++ + T Sbjct: 627 QEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTV------- 679 Query: 965 WEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQ 1024 S S+D+ T + E ++ D G QD+ +++R+W++ Q + Sbjct: 680 -------SSSSADQLSTSSSMTEGSGTMNKI---DLG-NCQDE---KQDRRWKKSFQGDD 725 Query: 1025 EQKRLQAEAEEQ 1036 L+ ++ Sbjct: 726 SDLLLKTRESDR 737 Score = 113 bits (282), Expect = 1e-24 Identities = 101/343 (29%), Positives = 160/343 (46%), Gaps = 60/343 (17%) Query: 1011 ERERKWEQQLQEEQE---QKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSY 1067 E ER+ +++ Q+EQE Q+R Q E ++ K E +K Q E+E E + R+ ++ Sbjct: 616 EEERRRQEKWQQEQERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDT 673 Query: 1068 DIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPS 1127 +P T +SS D+ + S+ T +G +D +GN Sbjct: 674 VVPFTVSSSS----ADQLSTSSS------MTEGSGTMNKID-LGNC-------------- 708 Query: 1128 GAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNS 1187 Q Q+ R + D+S + ++ ++ + G + G +L + +P S Sbjct: 709 ------QDEKQDRRWKKSFQGDDSDLLLKTRESDR--LEEKGSLTEG-ALAHSGNPVSKG 759 Query: 1188 WRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGV 1247 + L+ G + ++ P Q TSN P S+ VK T + Sbjct: 760 VHEDHQLDTEAGAPHCGTNPQLAQDPSQNQQTSN-----------PTHSSEDVKPKT--L 806 Query: 1248 ATTQSPTPRSHSPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCF 1307 +S + SPS R +S+SGK++CS C LGKGAAMIIE+L L +H+ CF Sbjct: 807 PLDKSINHQIESPSE-------RRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCF 859 Query: 1308 KCVACECDLGGSSSGAEVRIRNHQLYCNDCYLRFKS-GRPTAM 1349 +C C+ LG + SG +VRIRN L CNDCY+R +S G+PT + Sbjct: 860 RCGICKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 902 Score = 31.6 bits (70), Expect = 5.4 Identities = 58/271 (21%), Positives = 102/271 (37%), Gaps = 39/271 (14%) Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1070 E ++ + +EE + +EQ + Q R+ + + + + ++ RR S D+ Sbjct: 170 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 229 Query: 1071 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1129 K EE +R K +D ++ + + K +I + R E + + Sbjct: 230 KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 281 Query: 1130 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1188 + E + ILQ+ +R + + E + +P I+ R S + NL S Sbjct: 282 QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 324 Query: 1189 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1246 +LN P ++ S PPP+ +T R +S+ S KT T Sbjct: 325 ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 377 Query: 1247 VATTQSPTPRSHSPSASQSGSQLRNRSVSGK 1277 +P P S P SQ L+ V GK Sbjct: 378 AVPMLTPKPYS-QPKNSQ--DVLKTFKVDGK 405 >gi|163310749 LIM and calponin homology domains 1 isoform e [Homo sapiens] Length = 890 Score = 289 bits (740), Expect = 1e-77 Identities = 251/852 (29%), Positives = 404/852 (47%), Gaps = 155/852 (18%) Query: 206 KALEDSSFLKRSGRDSGYGDIWCPERGEFLAPPRHHKREDSFESLDSLGSRSLTSCSSDI 265 K +D KRS RDSGY D W ER + L+PPRH R+DSF+SLDS GSRS + S D+ Sbjct: 8 KDTDDIESPKRSIRDSGYIDCWDSERSDSLSPPRHG-RDDSFDSLDSFGSRSRQTPSPDV 66 Query: 266 TLRGGREGFESDTDSEFTF-KMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYV 324 LRG +G SD++S+ K+ D KDDMS RR S EPK+A+PFN++LPNKS Q +YV Sbjct: 67 VLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYV 126 Query: 325 PAPLRKKKPDKHEDNRRSWA---SPVYTEADGTFSRLFQKIYGENGSKSMSDVSAED--- 378 PAPLRKKK ++ E+ R+SW+ SP+ E R F+ S SM D+ E+ Sbjct: 127 PAPLRKKKAER-EEYRKSWSTATSPLGGE------RPFR-------STSMFDMRCEEEAA 172 Query: 379 VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEK---- 434 VQ + R E++Q I +QL+E+D KWQDDLA+WK RR+S + DL KK+EER+++EK Sbjct: 173 VQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLIKKEEERKKMEKLLAG 232 Query: 435 -QALEKSKRSSKTFKEMLQDRESQNQK--STVPSRRRMYSFDDVLEEGKRPPTMTVSEAS 491 + ++S KT++E++Q++E + ++ + R + +L++ T+SEA Sbjct: 233 EDGTSERRKSIKTYREIVQEKERRERELHEAYKNARSQEEAEGILQQ--YIERFTISEAV 290 Query: 492 YQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRST 551 ER+E S + + ++F + + L QS + A++ + +R++ Sbjct: 291 L--ERLEMPKILERSHSTEPNLSSFLNDPNPMK---YLRQQSLPPPKFTATVETTIARAS 345 Query: 552 QMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVED 611 ++++ + S S KT T + ++TP+P+ SQ + + +++ +D NG Sbjct: 346 VLDTSMSAGS--GSPSKTVTPKAVPMLTPKPY-SQPKNSQDVLKTFKVDGKVSVNG---- 398 Query: 612 IKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSK 671 E EE+ R +P SL++ Q Sbjct: 399 -----------------------------ETVHREEEKERECPTVAPAHSLTKSQMFEGV 429 Query: 672 ATLSSTSGLDLMSESGEGEI------SPQREVSRSQDQFSDMRISINQTPGKSLDFGFTI 725 A + S L+L ++G EI S +E++ + ++ GKS + Sbjct: 430 ARVHG-SPLELKQDNGSIEINIKKPNSVPQELAATTEKTEPNSQEDKNDGGKSRKGNIEL 488 Query: 726 KWDIPGIFVASVEAGSP-AEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLV 784 P F +V SP F + + + N D K+ E M+ E LV Sbjct: 489 ASSEPQHFTTTVTRCSPTVAFVEFPSSPQ---LKNDVSEEKDQKKPENEMSGKVE---LV 542 Query: 785 MDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESN 844 + ++ K SPE + ++T F + + +N Sbjct: 543 LS-QKVVKPKSPEPE----------------ATLTFPFLDKMPEAN-------------- 571 Query: 845 AFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQ 904 + L NL SQ S S P ++ W WD EEER+RQE+WQ Sbjct: 572 --------QLHLPNL--NSQVDSPSSEKS-------PVMTPFKFWAWDPEEERRRQEKWQ 614 Query: 905 KEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLAT 964 +EQ+RLLQE+YQ+EQ+KL+EEW++A++E E E +Y +EE ++ + T Sbjct: 615 QEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERKIIEDTVVPFTV------- 667 Query: 965 WEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQ 1024 S S+D+ T + E ++ D G QD+ +++R+W++ Q + Sbjct: 668 -------SSSSADQLSTSSSMTEGSGTMNKI---DLG-NCQDE---KQDRRWKKSFQGDD 713 Query: 1025 EQKRLQAEAEEQ 1036 L+ ++ Sbjct: 714 SDLLLKTRESDR 725 Score = 113 bits (282), Expect = 1e-24 Identities = 99/339 (29%), Positives = 157/339 (46%), Gaps = 58/339 (17%) Query: 1012 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPK 1071 R+ KW+Q+ QE Q+R Q E ++ K E +K Q E+E E + R+ ++ +P Sbjct: 609 RQEKWQQE-QERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDTVVPF 665 Query: 1072 TEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAEL 1131 T +SS D+ + S+ T +G +D +GN + Sbjct: 666 TVSSSSA----DQLSTSSSM------TEGSGTMNKID-LGNCQDEK-------------- 700 Query: 1132 ERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQP 1191 Q+ R + D+S + ++ ++ + G + G +L + +P S + Sbjct: 701 ------QDRRWKKSFQGDDSDLLLKTRESDR--LEEKGSLTEG-ALAHSGNPVSKGVHED 751 Query: 1192 PWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQ 1251 L+ G + ++ P Q TSN P S+ VK T + + Sbjct: 752 HQLDTEAGAPHCGTNPQLAQDPSQNQQTSN-----------PTHSSEDVKPKT--LPLDK 798 Query: 1252 SPTPRSHSPSASQSGSQLRNRSVSGKRICSYCNNILGKGAAMIIESLGLCYHLHCFKCVA 1311 S + SPS R +S+SGK++CS C LGKGAAMIIE+L L +H+ CF+C Sbjct: 799 SINHQIESPSE-------RRKSISGKKLCSSCGLPLGKGAAMIIETLNLYFHIQCFRCGI 851 Query: 1312 CECDLGGSSSGAEVRIRNHQLYCNDCYLRFKS-GRPTAM 1349 C+ LG + SG +VRIRN L CNDCY+R +S G+PT + Sbjct: 852 CKGQLGDAVSGTDVRIRNGLLNCNDCYMRSRSAGQPTTL 890 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 80.5 bits (197), Expect = 1e-14 Identities = 70/294 (23%), Positives = 136/294 (46%), Gaps = 17/294 (5%) Query: 893 QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNS 952 +E++ +R+++ ++EQ +++ +REQ+ RE+ R +Q+ RE + E+ Sbjct: 385 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE 444 Query: 953 MSLTTREPSLATW----EATWSEGSKSSDREGTRAGEEERRQ---PQEEVVHEDQGKKPQ 1005 L + W E T + ++ R EEERR+ EE +Q ++ + Sbjct: 445 QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE 504 Query: 1006 DQLVIERERKWEQQLQEEQEQKRLQ--AEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP 1063 QL E+E + EQ+L+ ++E++RLQ +E+Q R +E++R+ ++RE R+ Q RR Sbjct: 505 QQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR- 563 Query: 1064 VDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKE 1123 + + EE L R + R L + +++ + +RR ++ Sbjct: 564 -EQRLKREQEERRDQLL--KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620 Query: 1124 QVPSGAELERQQIL----QEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRR 1173 + E RQQ+L QE R++ L + R++ +E L ++R Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKR 674 Score = 70.5 bits (171), Expect = 1e-11 Identities = 53/172 (30%), Positives = 88/172 (51%), Gaps = 10/172 (5%) Query: 896 ERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSL 955 E K+Q+R ++ QDR+ QE+ ++E K RE R ++E +E EL L Sbjct: 224 EEKQQQR-RERQDRVFQEEEEKEWRK-RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL 281 Query: 956 TTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEE-----VVHEDQGKKPQDQLVI 1010 +E E + +++ R EEERR+ QEE E Q ++ + QL Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341 Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRR 1062 E+E + EQQL+ EQE++R + ++ +R EE++R+ ++ RE +R Q R Sbjct: 342 EQEERREQQLRREQEEERRE---QQLRREQEEERREQQLRREQQLRREQQLR 390 Score = 69.7 bits (169), Expect = 2e-11 Identities = 66/255 (25%), Positives = 121/255 (47%), Gaps = 42/255 (16%) Query: 893 QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNS 952 Q EER+++ R ++E+ +E+ Q+E+E+L E + ++ ERE D++ L Sbjct: 914 QREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK---LQQKE 970 Query: 953 MSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIER 1012 L EP E + +RE EEE +Q +E+++ E++ K+ R Sbjct: 971 EQLLGEEP----------EKRRRQEREKKYREEEELQQEEEQLLREEREKR--------R 1012 Query: 1013 ERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKT 1072 ++WE+Q +++ E LQ E E+ R E++R E ER QYR + ++ + Sbjct: 1013 RQEWERQYRKKDE---LQQEEEQLLREEREKRRLQERER-------QYR---EEEELQQE 1059 Query: 1073 EEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRR--SKKEQVPSGAE 1130 EE L G+ ++R EL+ + + +Q+ +RR ++ Q E Sbjct: 1060 EEQ----LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEE 1115 Query: 1131 L--ERQQILQEMRKR 1143 L E +Q+L+E R++ Sbjct: 1116 LQQEEEQLLREEREK 1130 Score = 68.9 bits (167), Expect = 3e-11 Identities = 66/275 (24%), Positives = 126/275 (45%), Gaps = 24/275 (8%) Query: 893 QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEA-----ERENSKYLDEELMV 947 QEEE + Q+R + EQ +++ +REQ REE +R +QE +RE + D+ L Sbjct: 522 QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR 581 Query: 948 LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEE-----VVHEDQGK 1002 RE + E + ++E R +R +P+EE + E+Q + Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641 Query: 1003 KPQDQLVIERERKWEQQLQEEQEQKRLQ----AEAEEQKRP---AEEQKRQAEIERETSV 1055 + Q QL E++ + EQ+L+ E+E++RL+ E EE++R AEE++ QA ++ + Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701 Query: 1056 RIYQYR-------RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLD 1108 +Q++ R Y P+ +E + + R +EL + + + Sbjct: 702 PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761 Query: 1109 QIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKR 1143 + + Q +++++ L + L+E R+R Sbjct: 762 EQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER 796 Score = 68.9 bits (167), Expect = 3e-11 Identities = 68/262 (25%), Positives = 127/262 (48%), Gaps = 34/262 (12%) Query: 892 DQEEERKRQERWQKEQDRLLQEKYQREQEKL---------REEWQRAKQEAERENSKYLD 942 ++ E+R+RQER +K ++ +E+ Q+E+E+L R+EW+R Q +++ + + Sbjct: 976 EEPEKRRRQEREKKYRE---EEELQQEEEQLLREEREKRRRQEWER--QYRKKDELQQEE 1030 Query: 943 EELMVLSSNSMSLTTREPSLATWEATWSEGSK--SSDREGTRAGEEERRQPQEEVVHEDQ 1000 E+L+ L RE E E + +RE R E ER+ +EE + +++ Sbjct: 1031 EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE 1090 Query: 1001 GKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQY 1060 + +++ R ++ E+Q +EE+E LQ E E+ R E++R+ E+ER QY Sbjct: 1091 EQLLREEPEKRRRQERERQCREEEE---LQQEEEQLLREEREKRRRQELER-------QY 1140 Query: 1061 RRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRS 1120 R + ++ + EE L + + R EL+ + + +Q+ +RR Sbjct: 1141 R---EEEEVQQEEEQ----LLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ 1193 Query: 1121 KKE-QVPSGAELERQQILQEMR 1141 ++E Q EL+RQ+ Q R Sbjct: 1194 ERERQYREEEELQRQKRKQRYR 1215 Score = 68.6 bits (166), Expect = 4e-11 Identities = 63/277 (22%), Positives = 119/277 (42%), Gaps = 26/277 (9%) Query: 892 DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 951 +QE E E ++Q+RL Q QR E+L W++ ++ ERE + +E+L + Sbjct: 143 EQERELAEGEEQSEKQERLEQRDRQRRDEEL---WRQRQEWQEREERRAEEEQLQSCKGH 199 Query: 952 SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK--------- 1002 E L E R+G +++RR+ Q+ V E++ K Sbjct: 200 ETEEFPDEEQLRRRELL------ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVL 253 Query: 1003 KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRR 1062 + +++ + E E + +++LQEE+EQ R E ++ EE+++Q + RE Q RR Sbjct: 254 RKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE-----QQLRR 308 Query: 1063 PVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKK 1122 + + EE ++ + R +L + +Q Q R ++ Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368 Query: 1123 EQVPSGAELERQQIL---QEMRKRTPLHNDNSWIRQR 1156 E+ +L R+Q L Q++R+ L + R++ Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405 Score = 68.2 bits (165), Expect = 5e-11 Identities = 76/280 (27%), Positives = 118/280 (42%), Gaps = 42/280 (15%) Query: 889 WVWDQEE--ERKRQE-------RWQKEQDRLLQEKYQREQEKLREEW---QRAKQEAERE 936 W W EE ER RQ R Q+E+ +E+ QREQ L EE QR +Q ERE Sbjct: 769 WQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRERE 828 Query: 937 NS-KYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEV 995 ++L+EE L RE + E E D+E R+ E+ R Q Sbjct: 829 KELQFLEEE--------EQLQRRERAQQLQE---EEDGLQEDQERRRSQEQRRDQKWRWQ 877 Query: 996 VHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSV 1055 + E++ ++ + + ++QL++EQ+ LQ E EE +R E++R+ E ER Sbjct: 878 LEEERKRRRH---TLYAKPALQEQLRKEQQL--LQEEEEELQREEREKRRRQEQER---- 928 Query: 1056 RIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTS 1115 QYR + ++ L +R K R Y +K K +G Sbjct: 929 ---QYREE------EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPE 979 Query: 1116 SQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQ 1155 +RR ++E+ E +Q+ Q +R+ W RQ Sbjct: 980 KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019 Score = 67.0 bits (162), Expect = 1e-10 Identities = 64/278 (23%), Positives = 120/278 (43%), Gaps = 24/278 (8%) Query: 890 VWDQEEE---RKRQERWQKEQDRLLQEKYQREQEKLREEWQRAK---QEAERENSKYLDE 943 V+ +EEE RKR+ +KE+++L +E+ QR++E EE Q K QE RE + + Sbjct: 237 VFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ 296 Query: 944 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGE-----EERRQPQEEVVHE 998 + + + E E + + +E R + EERR+ Q E Sbjct: 297 QQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE 356 Query: 999 DQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIY 1058 ++ ++ Q + E ER+ +Q +E+Q ++ Q E+Q R ++ +R+ ++ RE +R Sbjct: 357 EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 416 Query: 1059 QYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELD--------DYSTNKNGNNKYLDQI 1110 Q R + EE +R + R E + + T ++ + Q+ Sbjct: 417 QQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476 Query: 1111 GNMTSSQRRSK-----KEQVPSGAELERQQILQEMRKR 1143 +RR + +E+ E QQ+ +E +R Sbjct: 477 KRDQEEERRERWLKLEEEERREQQERREQQLRREQEER 514 Score = 65.1 bits (157), Expect = 4e-10 Identities = 70/286 (24%), Positives = 127/286 (44%), Gaps = 42/286 (14%) Query: 894 EEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSM 953 E + +++E Q+E+++LL+E+ ++ + + RE R ++E ++E + L EE + Sbjct: 1077 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQEL 1136 Query: 954 SLTTREPSLATWEATW-----SEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQL 1008 RE E E + + E EEE +Q +E+++ E+Q K+ Q Sbjct: 1137 ERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ--- 1193 Query: 1009 VIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVR---IY------- 1058 ERER++ ++ +E Q QKR Q +E +R + K Q E E+E +VR +Y Sbjct: 1194 --ERERQYREE-EELQRQKRKQRYRDEDQR--SDLKWQWEPEKENAVRDNKVYCKGRENE 1248 Query: 1059 QYRRPVDSYDIPKTEEASSGFLPG-----DRNKSR-------------STTELDDYSTNK 1100 Q+R+ DS + + L G DR + R E ++ K Sbjct: 1249 QFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAK 1308 Query: 1101 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPL 1146 + K ++ + + ++ Q E +Q+LQE R+ PL Sbjct: 1309 RRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQE-REEQPL 1353 Score = 62.8 bits (151), Expect = 2e-09 Identities = 50/189 (26%), Positives = 96/189 (50%), Gaps = 26/189 (13%) Query: 893 QEEERKRQER-WQKEQDRLLQEK---YQREQEKLREEWQRAKQEAERENSKYLDEELMVL 948 Q++ R+RQ+R +Q+E+++ +++ ++E+EKL+EE + ++E + E +E+L L Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE-----EEQLRKL 281 Query: 949 SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQL 1008 + +E + + E R +EERR+ QE E Q ++ + QL Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER--REQQEERREQQL 339 Query: 1009 VIERERKWEQQLQ--------------EEQEQKR-LQAEAEEQKRPAEEQKRQAEIERET 1053 E+E + EQQL+ E++E++R Q E+Q R ++ +R+ ++ RE Sbjct: 340 RREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399 Query: 1054 SVRIYQYRR 1062 +R Q R Sbjct: 400 QLRREQQLR 408 Score = 58.9 bits (141), Expect = 3e-08 Identities = 59/262 (22%), Positives = 125/262 (47%), Gaps = 22/262 (8%) Query: 892 DQEEERKRQERWQK---EQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVL 948 ++E + +RQER Q+ ++DR +E+ Q QE EE Q +QE +R+ + +E+ + Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG--EEQQLRRQERDRKFRE--EEQQLRR 1702 Query: 949 SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQL 1008 E L E + R+ T + R++ +++ E+Q + +++ Sbjct: 1703 QERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQ 1762 Query: 1009 VI---ERERKW--EQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE--TSVRIYQYR 1061 + ER+RK+ E+QL++E+E+++L+++ ++K EEQ RQ E++ R +YR Sbjct: 1763 QLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYR 1822 Query: 1062 RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSK 1121 + + + E+ + + R + ++T + + ++ +RR + Sbjct: 1823 WEEEQLQLEEQEQRLR------QERDRQYRAEEQFATQEKSRREE-QELWQEEEQKRRQE 1875 Query: 1122 KEQVPSGAELERQQILQEMRKR 1143 +E+ + RQQ +E R R Sbjct: 1876 RERKLREEHIRRQQ-KEEQRHR 1896 Score = 58.5 bits (140), Expect = 4e-08 Identities = 55/264 (20%), Positives = 120/264 (45%), Gaps = 19/264 (7%) Query: 892 DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 951 ++E++ RQER +K ++ +E+ R QE+ R+ + +Q + + K+ +EE ++ Sbjct: 1418 EEEQQLSRQERDRKFRE---EEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE 1474 Query: 952 SMSLTTREPSLATWEATWSEGSKSSDR----EGTRAGEEERR-QPQEEVVHEDQGKKP-- 1004 L +E E + DR + R+ E ER+ +E+ +H Q ++ Sbjct: 1475 EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFL 1534 Query: 1005 QDQLVIERERKWEQQLQEE----QEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQY 1060 Q++ + R+ + +Q+ Q+ +E+++L+ E EEQ+ +E+ R+ +E + R Q Sbjct: 1535 QEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594 Query: 1061 RRPVDSYDIPKTEEASSGFLPGDRNKSRSTTEL-----DDYSTNKNGNNKYLDQIGNMTS 1115 R+ ++ + +E K R +L + + + K+L++ + Sbjct: 1595 RKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRR 1654 Query: 1116 SQRRSKKEQVPSGAELERQQILQE 1139 +R + E +Q+LQE Sbjct: 1655 QEREQQLRHDRDRKFREEEQLLQE 1678 Score = 57.4 bits (137), Expect = 9e-08 Identities = 65/266 (24%), Positives = 119/266 (44%), Gaps = 29/266 (10%) Query: 889 WVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVL 948 W+ +EE + ++ +K+Q + QE+ +RE+ EE +R +Q+ RE ++E Sbjct: 457 WLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE---- 512 Query: 949 SSNSMSLTTREPSLATWEATWSEGSKSSDREGTR----AGEEERRQPQEEVVHEDQGKKP 1004 L +E + SE ++E R EEE+R QE E + K+ Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER--REQRLKRE 570 Query: 1005 Q----DQLVIERERKWEQQLQEEQEQKRLQ-AEAEEQKRPAEEQKRQAEIERETSVRIYQ 1059 Q DQL+ E + +Q+L+ EQE++ Q + EE +R +E++R+ ++RE + Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEP---EE 627 Query: 1060 YRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRR 1119 RR + K+EE + R E + + + L+Q + R Sbjct: 628 ERR----QQLLKSEEQEE---RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER 680 Query: 1120 SKKEQVPSGAELERQQILQEMRKRTP 1145 ++E AE E++Q + ++ R P Sbjct: 681 REQEL----AEEEQEQARERIKSRIP 702 Score = 56.2 bits (134), Expect = 2e-07 Identities = 59/286 (20%), Positives = 129/286 (45%), Gaps = 33/286 (11%) Query: 891 WDQEE----ERKRQERWQKEQDRLLQEKYQREQEKLREEWQ--RAKQEAERENSKYLDEE 944 W Q + E ++ ER ++++ + K Q E++ LREE + R +QE +R K+ +EE Sbjct: 1286 WQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR---KFREEE 1342 Query: 945 LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEE----VVHEDQ 1000 ++ L +E + + E +G + EEE+R ++E + E+Q Sbjct: 1343 QLLQEREEQPLRRQER-----DRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQ 1397 Query: 1001 GKKPQD---QLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRI 1057 + Q+ QL +R+RK+ ++ Q+ Q+R + EE+++ +++ + +E E +R Sbjct: 1398 QLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQ 1457 Query: 1058 YQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQ 1117 ++R+ + + + E + + R E + + + K+ +Q + Sbjct: 1458 ERHRKFREEEQLLQEREEQQ---LHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPE 1514 Query: 1118 RRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1163 R+ +E+ QQ+ ++ R+R L + RQ ++ Sbjct: 1515 RKFLEEE---------QQLHRQQRQRKFLQEEQQLRRQERGQQRRQ 1551 Score = 56.2 bits (134), Expect = 2e-07 Identities = 60/271 (22%), Positives = 122/271 (45%), Gaps = 37/271 (13%) Query: 886 PSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEEL 945 P R ++E++ RQ+R Q K+ +E+++LR + +R +Q + + K+ +EE Sbjct: 1513 PERKFLEEEQQLHRQQR---------QRKFLQEEQQLRRQ-ERGQQRRQDRDRKFREEEQ 1562 Query: 946 MVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ----G 1001 + L+ +E DR+ ++ RRQ QE ED+ Sbjct: 1563 LRQEREEQQLSRQE----------------RDRKFRLEEQKVRRQEQERKFMEDEQQLRR 1606 Query: 1002 KKPQDQLVIERERKW--EQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQ 1059 ++ Q QL ER+RK+ ++QL +E+E+++L + E ++ EE+ + ERE +R + Sbjct: 1607 QEGQQQLRQERDRKFREDEQLLQEREEQQLHRQ-ERDRKFLEEEPQLRRQEREQQLRHDR 1665 Query: 1060 YRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQ-R 1118 R+ + + + E + + R E + + K+L + + + Sbjct: 1666 DRKFREEEQLLQEGEEQQ---LRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELE 1722 Query: 1119 RSKKEQVPSGAELERQQILQEMRKRTPLHND 1149 R +E+ E E++Q+ ++ R R L + Sbjct: 1723 RKFREEEQLRQETEQEQLRRQERYRKILEEE 1753 Score = 55.8 bits (133), Expect = 3e-07 Identities = 62/280 (22%), Positives = 115/280 (41%), Gaps = 43/280 (15%) Query: 892 DQEEERKRQERWQKEQDRLLQEKY-------------------QREQEKLREEWQRAKQE 932 D+E R+RQE WQ+ ++R +E+ +RE +LR + + KQ+ Sbjct: 170 DEELWRQRQE-WQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQ 228 Query: 933 AERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQ 992 RE + +E RE L E E RE E+ R+ + Sbjct: 229 QRRERQDRVFQE-----EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283 Query: 993 EEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052 +E+ E Q ++ Q Q + ++ +Q +E +EQ +E++R +E++ Q E RE Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEERREQ-------QEERREQQERREQQEERRE 336 Query: 1053 TSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGN 1112 +R Q R + EE L ++ + R +L + L + Sbjct: 337 QQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQL--------RREQQLRREQQ 388 Query: 1113 MTSSQRRSKKEQVPSGAELERQQIL---QEMRKRTPLHND 1149 + Q+ +++Q+ +L R+Q L Q++R+ L + Sbjct: 389 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428 Score = 55.8 bits (133), Expect = 3e-07 Identities = 60/300 (20%), Positives = 124/300 (41%), Gaps = 48/300 (16%) Query: 892 DQEEERKRQERWQKEQDRLLQEKYQREQEKLRE-------EWQRAKQEAERENSKYLDEE 944 + EEER++Q +EQ+ Q++ +REQ++ RE E +R +Q +RE+ + E+ Sbjct: 624 EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683 Query: 945 LMVLSSNSMSLTTREPSLATWE------------ATWSEGSKSSDREGTRAGEEERRQPQ 992 + + + + W+ +S K + + EE+RR+ + Sbjct: 684 ELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRE 743 Query: 993 EEV--VHEDQGKKPQDQLVIERERKWEQQLQE----------------EQEQKRLQAEAE 1034 E+ E++ + Q + R+ W+ Q +E EQ +++L+AE Sbjct: 744 SELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER 803 Query: 1035 EQKR----PAE---EQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKS 1087 +Q+ P E EQ+R+ ERE ++ + + + + + L D+ + Sbjct: 804 QQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERR 863 Query: 1088 RSTTELDD----YSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKR 1143 RS + D + + + ++ K++Q+ E E Q+ +E R+R Sbjct: 864 RSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRR 923 Score = 55.8 bits (133), Expect = 3e-07 Identities = 68/290 (23%), Positives = 131/290 (45%), Gaps = 33/290 (11%) Query: 890 VWDQEEERKRQE---RWQKEQDRLLQEK---YQREQEKLREEWQRAKQEAERENSKYLDE 943 V +EE+ R+E R ++E +R +E+ Q E++ LREE ++ +QE ER+ + +E Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE--EE 1203 Query: 944 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG---TRAGEEER-RQPQEEVVHED 999 EL + S W+ W +++ R+ + E E+ RQ ++ + + Sbjct: 1204 ELQRQKRKQRYRDEDQRSDLKWQ--WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDR 1261 Query: 1000 QGKKPQDQLVIERE--------RKWEQQ----LQEEQEQKRLQAEAEEQKRPAEEQKRQA 1047 Q ++ L+ E++ R+W+Q+ +EEQ ++ Q EA+ + R ++E+K+ Sbjct: 1262 QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLL 1321 Query: 1048 EIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYL 1107 ERE R + R + E +R++ EL ++ K+L Sbjct: 1322 REEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEEL----RHQEQGRKFL 1377 Query: 1108 DQIGNMTSSQRRSK--KEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQ 1155 ++ + +R K KE+ + ER+Q L++ R R + RQ Sbjct: 1378 EEEQRLRRQERERKFLKEEQQLRCQ-EREQQLRQDRDRKFREEEQQLSRQ 1426 Score = 54.7 bits (130), Expect = 6e-07 Identities = 63/292 (21%), Positives = 121/292 (41%), Gaps = 32/292 (10%) Query: 892 DQEEERKRQERWQKEQDRLLQEK----YQREQEK--LREEWQRAKQEAERENSKYLD--E 943 +QE+ R+ +ER +E++ L ++K Y+ E ++ L+ +W+ K+ A R+N Y E Sbjct: 1187 EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246 Query: 944 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003 L R+ + + ++E R + +R P+EE + ++ K+ Sbjct: 1247 NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306 Query: 1004 PQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEE------QKRQAEIERETSVRI 1057 + R+RK QE+K+L E E+KR +E ++ Q ERE Sbjct: 1307 AK-----RRDRK-------SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR 1354 Query: 1058 YQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQ 1117 Q R + + +E FL ++ R E + + +Q + Sbjct: 1355 RQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR 1414 Query: 1118 RRSKKEQVPSGAELER------QQILQEMRKRTPLHNDNSWIRQRSASVNKE 1163 + ++EQ S E +R QQ+ ++ R+R L + ++R +E Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE 1466 Score = 53.9 bits (128), Expect = 1e-06 Identities = 36/159 (22%), Positives = 77/159 (48%), Gaps = 5/159 (3%) Query: 894 EEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSM 953 EEE+ R ER +++ R +++ RE+E+LR+E + + ++ + K+ +EE + Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ 1810 Query: 954 SLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERE 1013 L P + W E + + R +E RQ + E Q K +++ + +E Sbjct: 1811 QL---RPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQE 1867 Query: 1014 RKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052 EQ+ ++E+E+K + Q++ + ++ EI+ + Sbjct: 1868 E--EQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904 Score = 52.0 bits (123), Expect = 4e-06 Identities = 42/171 (24%), Positives = 88/171 (51%), Gaps = 16/171 (9%) Query: 893 QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERE-----NSKYLDEELMV 947 +E+E+ QER +++ R +R+++ L EE Q +QE E++ + K+ +EE ++ Sbjct: 1622 REDEQLLQEREEQQLHR-----QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLL 1676 Query: 948 LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE-EVVHEDQGKKPQD 1006 L +E E + +R+ + ++ RRQ E + E+Q ++ + Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736 Query: 1007 QLVIERERKW-----EQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052 Q + R+ ++ E+QL+ E+E+++L+ + ++K EEQ RQ E++ Sbjct: 1737 QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787 Score = 48.5 bits (114), Expect = 4e-05 Identities = 62/313 (19%), Positives = 116/313 (37%), Gaps = 40/313 (12%) Query: 268 RGGREGFESDTDSEFTFKMQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAP 327 R R+ E + +FT++ Q K + +R+SA P + + +Q P Sbjct: 753 RAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLP 812 Query: 328 LRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRY 387 ++K + R + E + R + A+ +Q Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQLQRRER---------------AQQLQEEEDGLQ 857 Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRK-----------SYTSDLQKKKEEREEIEKQA 436 E+ ++ +SQ + +DQKW+ L + + RR+ + Q +EE EE++++ Sbjct: 858 EDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREE 917 Query: 437 LEKSKRSSK----TFKEMLQDRESQ-----NQKSTVPSRRRMYSFDDVLEEGKRPPTMTV 487 EK +R + +E LQ E Q +K R R Y D L++ + Sbjct: 918 REKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEE 977 Query: 488 SEASYQSERVEEKGATYPSEIPKEDSTTFAKRED---RVTTEIQLPSQSPVEEQSPASLS 544 E + ER EK E+ +E+ + + R E Q + ++++ L Sbjct: 978 PEKRRRQER--EKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLR 1035 Query: 545 SLRSRSTQMESTR 557 R + E R Sbjct: 1036 EEREKRRLQERER 1048 Score = 45.8 bits (107), Expect = 3e-04 Identities = 41/214 (19%), Positives = 92/214 (42%), Gaps = 6/214 (2%) Query: 328 LRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDV---SAEDVQNLRQ 384 LR+K ++ + RR V+ E + R + + + K + E + Q Sbjct: 218 LRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQ 277 Query: 385 LRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 444 LR E Q+++ + +E++Q+ Q + + RRK ++++E RE+ E++ ++ +R Sbjct: 278 LRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQ 337 Query: 445 KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATY 504 + +E + RE Q ++ RR + EE + + + + E+ Sbjct: 338 QLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRR 397 Query: 505 PSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQ 538 ++ +E +RE ++ E QL + + + Sbjct: 398 EQQLRREQQ---LRREQQLRREQQLRREQQLRRE 428 Score = 45.4 bits (106), Expect = 4e-04 Identities = 39/191 (20%), Positives = 86/191 (45%), Gaps = 11/191 (5%) Query: 847 ESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKE 906 E + + + L+R+ ++ + + + P+ + R +EEE+ RQER +++ Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787 Query: 907 QDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWE 966 ++ RE+E+LR+E + + ++ + KY EE + L +E L Sbjct: 1788 LRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE------EQLQLEEQEQRLRQ-- 1839 Query: 967 ATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQ 1026 + E E+ RR+ QE E+Q ++ + + + E QQ +E++ + Sbjct: 1840 ---ERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHR 1896 Query: 1027 KRLQAEAEEQK 1037 + + +++E K Sbjct: 1897 QVGEIKSQEGK 1907 Score = 42.4 bits (98), Expect = 0.003 Identities = 32/155 (20%), Positives = 71/155 (45%), Gaps = 15/155 (9%) Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQA 436 E+ + ++L EE ++ + ++K + KWQ L D R+S +K+E + ++Q Sbjct: 677 EEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQE 736 Query: 437 LEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEE---------GKRPPTMTV 487 ++ +R S+ Q+ E +++ +RR +++ EE RPP Sbjct: 737 EKRRRRESEL---QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQ 793 Query: 488 SEASYQSERVEEKGATYPSEIPKEDSTTFAKREDR 522 E ++E +++ + +P+E+ +R+ R Sbjct: 794 RERQLRAEERQQREQRF---LPEEEEKEQRRRQRR 825 Score = 40.4 bits (93), Expect = 0.012 Identities = 52/250 (20%), Positives = 105/250 (42%), Gaps = 28/250 (11%) Query: 334 DKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKI 393 ++ E RR Y + D + +++ GE K + + +L+ EE Q + Sbjct: 946 EEREKRRRQERERQYRK-DKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLL 1004 Query: 394 KSQL-KEQDQKWQDDLAKWKDRRKSYTSDLQKKKEE--REEIEKQALEKSKRSSKTFKEM 450 + + K + Q+W+ K KD +LQ+++E+ REE EK+ L++ +R + +E+ Sbjct: 1005 REEREKRRRQEWERQYRK-KD-------ELQQEEEQLLREEREKRRLQERERQYREEEEL 1056 Query: 451 LQDRESQNQKSTVPSRR----RMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPS 506 Q+ E + RR R Y ++ L++ + E + ER E+ Sbjct: 1057 QQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER--ERQCREEE 1114 Query: 507 EIPKEDSTTFAKRED---RVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLP 563 E+ +E+ + + R E Q + V+++ L + + E L Sbjct: 1115 ELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE-------LE 1167 Query: 564 RSYRKTDTVR 573 R YR+ + ++ Sbjct: 1168 RQYREEEELQ 1177 Score = 37.7 bits (86), Expect = 0.075 Identities = 39/202 (19%), Positives = 81/202 (40%), Gaps = 15/202 (7%) Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKD---------RRKSYTSDLQKKKE 427 E+ + +QLR E+ + + QL+ + Q ++ + + R + + Q ++E Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428 Query: 428 EREEIEKQALEKSKRSSKTFKEMLQ-----DRESQNQKSTVPSRRRMYSFDDVLEEGKRP 482 + EE +Q E+ +R + +E + RE + ++ R++ D E +R Sbjct: 429 QEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERW 488 Query: 483 PTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPAS 542 + E Q ER E++ E +E + E+R+ ++ Q E++ Sbjct: 489 LKLEEEERREQQERREQQ-LRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERRE 547 Query: 543 LSSLRSRSTQMESTRVSASLPR 564 R ++E R L R Sbjct: 548 QLLKREEEKRLEQERREQRLKR 569 Score = 37.7 bits (86), Expect = 0.075 Identities = 43/229 (18%), Positives = 98/229 (42%), Gaps = 40/229 (17%) Query: 329 RKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYE 388 R+++ ++HE RR + ++ E + + E+ + ++ R + Sbjct: 460 REEETERHEQERRK--------------QQLKRDQEEERRERWLKLEEEERREQQERREQ 505 Query: 389 EMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFK 448 ++++ + + +EQ K Q++ + + R +S ++++E RE++ K+ E+ KR + + Sbjct: 506 QLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKR--EEEKRLEQERR 563 Query: 449 EMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEI 508 E RE + ++ + R EE +R + Q ER+E++ + Sbjct: 564 EQRLKREQEERRDQLLKR----------EEERRQQRL----KREQEERLEQR-------L 602 Query: 509 PKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTR 557 +E+ + E R E +L + P EE+ L S + + R Sbjct: 603 KREEVERLEQEERR---EQRLKREEPEEERRQQLLKSEEQEERRQQQLR 648 Score = 35.8 bits (81), Expect = 0.29 Identities = 33/195 (16%), Positives = 82/195 (42%), Gaps = 12/195 (6%) Query: 360 QKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYT 419 Q++ E + + E+ + ++L+ E+ ++++ +LK ++ + + ++RR+ Sbjct: 565 QRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQ----EERREQRL 620 Query: 420 SDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEG 479 + ++E R+++ K ++ +R + +E Q+R Q K R EE Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQ-QERREQRLKREEEEERLEQRLKREHEEE 679 Query: 480 KRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQS 539 +R + E ER++ S IPK ++ + R + P + + + Sbjct: 680 RREQELAEEEQEQARERIK-------SRIPKWQWQLESEADARQSKVYSRPRKQEGQRRR 732 Query: 540 PASLSSLRSRSTQME 554 R R ++++ Sbjct: 733 QEQEEKRRRRESELQ 747 Score = 35.4 bits (80), Expect = 0.37 Identities = 28/124 (22%), Positives = 62/124 (50%), Gaps = 1/124 (0%) Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQA 436 E+ Q RQ R + ++ + QL+ Q+++ + + + RR+ +++++ R+E E++ Sbjct: 1680 EEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQ 1739 Query: 437 LEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSER 496 L + +R K +E E + Q+ R R + ++ L + +R S+ S + R Sbjct: 1740 LRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQ-EREEQQLRSQESDRKFR 1798 Query: 497 VEEK 500 EE+ Sbjct: 1799 EEEQ 1802 Score = 35.0 bits (79), Expect = 0.49 Identities = 20/78 (25%), Positives = 45/78 (57%), Gaps = 4/78 (5%) Query: 974 KSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQA-- 1031 K ++E A EE+ + QE + D+ ++ D+ + + ++W+++ + E+++LQ+ Sbjct: 140 KRQEQERELAEGEEQSEKQERLEQRDRQRR--DEELWRQRQEWQEREERRAEEEQLQSCK 197 Query: 1032 EAEEQKRPAEEQKRQAEI 1049 E ++ P EEQ R+ E+ Sbjct: 198 GHETEEFPDEEQLRRREL 215 Score = 35.0 bits (79), Expect = 0.49 Identities = 22/97 (22%), Positives = 51/97 (52%), Gaps = 3/97 (3%) Query: 388 EEMQKIKSQL--KEQDQKWQDDLAK-WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 444 EE+Q+ + QL +E++++ + +L + +++ + + Q +EE E+ +Q LE+ R Sbjct: 1114 EELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREE 1173 Query: 445 KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKR 481 + ++ + + Q+ R R Y ++ L+ KR Sbjct: 1174 EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKR 1210 Score = 35.0 bits (79), Expect = 0.49 Identities = 28/153 (18%), Positives = 72/153 (47%), Gaps = 13/153 (8%) Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQA 436 ED Q + +++Q + + +E+D+ + + +W+ R + + + Q ++EE++E +++ Sbjct: 1254 EDSQLRDRQSQQDLQHLLGEQQERDR--EQERRRWQQRDRHFPEEEQLEREEQKEAKRR- 1310 Query: 437 LEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSE- 495 R S+ K++L++ + ++ R+ + E ++P + ++ E Sbjct: 1311 ----DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEE 1366 Query: 496 -RVEEKGATYPSEIPK----EDSTTFAKREDRV 523 R +E+G + E + E F K E ++ Sbjct: 1367 LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL 1399 Score = 34.7 bits (78), Expect = 0.64 Identities = 28/138 (20%), Positives = 63/138 (45%), Gaps = 14/138 (10%) Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKW-------------QDDLAKWKDRRKSYTSDLQ 423 E+ Q LRQ R+ + ++ + L+E++++ + L + + RK +L+ Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELR 1509 Query: 424 KKKEEREEIEK-QALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRP 482 ++ ER+ +E+ Q L + +R K +E Q R + + R R + ++ L + + Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569 Query: 483 PTMTVSEASYQSERVEEK 500 ++ E + E+K Sbjct: 1570 QQLSRQERDRKFRLEEQK 1587 Score = 34.7 bits (78), Expect = 0.64 Identities = 39/199 (19%), Positives = 85/199 (42%), Gaps = 10/199 (5%) Query: 379 VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALE 438 +Q +QLR +E+++ + +E++Q Q+ + R++ Y L+++ + R E E+Q L Sbjct: 1710 LQEEQQLRRQELER---KFREEEQLRQETEQEQLRRQERYRKILEEE-QLRPEREEQQLR 1765 Query: 439 KSKRSSKTFKE--MLQDRESQNQKSTVPSR--RRMYSFDDVLEEGKRPPTMTVSEASYQS 494 + +R K +E + Q+RE Q +S R R EE + P + ++ Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE 1825 Query: 495 ERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQME 554 E+++ + + +E + E T E + + ++ R R + E Sbjct: 1826 EQLQLE--EQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREE 1883 Query: 555 STRVSASLPRSYRKTDTVR 573 R + +R+ ++ Sbjct: 1884 HIRRQQKEEQRHRQVGEIK 1902 Score = 34.3 bits (77), Expect = 0.83 Identities = 39/216 (18%), Positives = 90/216 (41%), Gaps = 15/216 (6%) Query: 963 ATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQ- 1021 A +AT + K + +G + ++RRQ +++ E + ++ +++ R +K ++Q + Sbjct: 88 ALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERE 147 Query: 1022 ----EEQEQKRLQAEAEEQKRPAEE-----QKRQAEIERETSVRIYQYRRPVDSYDIPKT 1072 EEQ +K+ + E +++R EE Q+ Q ER Q + ++ + P Sbjct: 148 LAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDE 207 Query: 1073 EEASSGFL-----PGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPS 1127 E+ L G K + E D + ++ + + + + ++E+ Sbjct: 208 EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267 Query: 1128 GAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1163 EL+ ++ +R L + Q+ + +E Sbjct: 268 QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE 303 Score = 34.3 bits (77), Expect = 0.83 Identities = 28/99 (28%), Positives = 54/99 (54%), Gaps = 18/99 (18%) Query: 377 EDVQNLRQLRYE-----EMQKIKSQLKEQ------DQKWQDD---LAKWKDRRKSYTSDL 422 E+ Q LR+ E E Q+++ Q +EQ D+K++++ L++ + RK + Sbjct: 1378 EEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQ 1437 Query: 423 QKKKEERE----EIEKQALEKSKRSSKTFKEMLQDRESQ 457 Q +++ERE E E+Q ++ R + +++LQ+RE Q Sbjct: 1438 QVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQ 1476 Score = 33.9 bits (76), Expect = 1.1 Identities = 27/117 (23%), Positives = 60/117 (51%), Gaps = 12/117 (10%) Query: 365 ENGSKSMSDVSAEDVQNLRQLRYEEM-QKIKSQLKEQDQKWQDDLAKWKD----RRKSYT 419 E + ++ E+ Q LR+ R + Q+++ Q +E+++ Q++ ++ RR+ Sbjct: 1107 ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQEL 1166 Query: 420 SDLQKKKEEREEIEKQAL--EKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDD 474 +++EE ++ E+Q L E+ KR + ++ ++ E Q QK R++ Y +D Sbjct: 1167 ERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK-----RKQRYRDED 1218 Score = 33.5 bits (75), Expect = 1.4 Identities = 37/241 (15%), Positives = 94/241 (39%), Gaps = 17/241 (7%) Query: 343 WASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQ-- 400 W + +EAD S+++ + + G + + + + +L+++E ++ Q +E+ Sbjct: 704 WQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQ 763 Query: 401 ----DQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRES 456 +WQ A+ K R + E+ E + +A E+ +R + E + + Sbjct: 764 RRDFTWQWQ---AEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQR 820 Query: 457 QNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTF 516 + Q+ + ++ L+ +R + E Q ++ + E ++ + Sbjct: 821 RRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRS----QEQRRDQKWRW 876 Query: 517 AKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQME----STRVSASLPRSYRKTDTV 572 E+R L ++ ++EQ L+ +++ R R YR+ + + Sbjct: 877 QLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQL 936 Query: 573 R 573 + Sbjct: 937 Q 937 Score = 33.1 bits (74), Expect = 1.9 Identities = 25/91 (27%), Positives = 51/91 (56%), Gaps = 10/91 (10%) Query: 375 SAEDVQNL---RQLRYEEMQKIKSQLK-----EQDQKWQDDLAKWKDRRKSYTSDLQKKK 426 S +D+Q+L +Q R E ++ + Q + E++Q +++ + K R + + Q + Sbjct: 1263 SQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLR 1322 Query: 427 EEREEIEKQALEKSKRSSKTFKEMLQDRESQ 457 EERE EK+ +++ R + +++LQ+RE Q Sbjct: 1323 EERE--EKRRRQETDRKFREEEQLLQEREEQ 1351 Score = 32.7 bits (73), Expect = 2.4 Identities = 32/166 (19%), Positives = 76/166 (45%), Gaps = 17/166 (10%) Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQA 436 + +++ R ++ E +++ + +EQ + Q+ K+++ + L++++ ER+ ++++ Sbjct: 1659 QQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQ----QLRRQERERKFLQEEQ 1714 Query: 437 LEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSER 496 + + + F+E Q R+ Q+ RR + +LEE + P E Q R Sbjct: 1715 QLRRQELERKFREEEQLRQETEQEQL----RRQERYRKILEEEQLRP-----EREEQQLR 1765 Query: 497 VEEKGATYPSE----IPKEDSTTFAKREDRVTTEIQLPSQSPVEEQ 538 +E+ + E +E+ ++ DR E + Q E+Q Sbjct: 1766 RQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQ 1811 Score = 31.6 bits (70), Expect = 5.4 Identities = 18/75 (24%), Positives = 44/75 (58%), Gaps = 3/75 (4%) Query: 384 QLRYE-EMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKR 442 QLR E E Q++ Q +++ + ++ + +++ + + D Q+ + R+E ++Q ++ R Sbjct: 1562 QLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLR--RQEGQQQLRQERDR 1619 Query: 443 SSKTFKEMLQDRESQ 457 + +++LQ+RE Q Sbjct: 1620 KFREDEQLLQEREEQ 1634 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 77.4 bits (189), Expect = 9e-14 Identities = 94/392 (23%), Positives = 166/392 (42%), Gaps = 59/392 (15%) Query: 769 EWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEK---SSNLSVTTDFSES 825 E ++ + + H +++R A S K D E+ S L T +E Sbjct: 163 ESKDLAGRLHHSWHFAGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEE 222 Query: 826 LQSSNIESKEINGIHDESNAFESKASE-SISLKNLKRRSQFFEQGSSDSVVPDLPVPTIS 884 L+ N E +E + ES+ SE +++K LKR+ + + ++P + T+ Sbjct: 223 LKKKNAELQE------KLPLAESEKSEIQLNVKELKRKLE-----RAKFLLPQVQTNTLQ 271 Query: 885 APSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAE---------R 935 +W QEEE + QE+ ++Q+ EK R++E+LRE+ + +++ E R Sbjct: 272 EE---MWRQEEELREQEKKIRKQE----EKMWRQEERLREQEGKMREQEEKMWRQEKRLR 324 Query: 936 ENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEV 995 E K L E+ L E E W + K ++E +EER QE+ Sbjct: 325 EQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 384 Query: 996 VHEDQGKKPQDQLVIERERKWEQ--QLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1053 + E Q +K +DQ ER WEQ +L+E++E+ R Q + EQ E+K+ E E+ Sbjct: 385 MRE-QEQKMRDQ----EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEK-- 437 Query: 1054 SVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNM 1113 KT + +R + R ++ T + K Q NM Sbjct: 438 -----------------KTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 480 Query: 1114 TSSQRRS-KKEQVPSGAE-LERQQILQEMRKR 1143 + + +++++P E L Q+ +QE ++ Sbjct: 481 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512 Score = 74.7 bits (182), Expect = 6e-13 Identities = 46/171 (26%), Positives = 90/171 (52%), Gaps = 4/171 (2%) Query: 890 VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAE-RENSKYLDEELMVL 948 +W+QEE+ + QE+ +Q+ +++K Q +++K ++ ++ ++E RE K + EE ++ Sbjct: 546 MWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 605 Query: 949 SSNSMSLTTREPSLATWEAT-WSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQ 1007 + +E + E W + K ++E +EE+ QEE + E Q Q + Sbjct: 606 REQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKE 665 Query: 1008 LVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKR--QAEIERETSVR 1056 + E E+ EQ+ +EQE+K + E E+K +E+K Q ++ E S+R Sbjct: 666 KLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR 716 Score = 70.1 bits (170), Expect = 1e-11 Identities = 46/176 (26%), Positives = 86/176 (48%), Gaps = 13/176 (7%) Query: 890 VWDQEEERKRQER--WQKEQDRLLQEKYQREQEKLREEWQRA-KQEAERENSKYLDEELM 946 +W+QEE+ + QE W++E+ QE+ EQ++L E+ ++ + E +E K ++E Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEK 685 Query: 947 VLSSNSMSLTTREPSLATWEAT-WSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK--- 1002 + M T+E TW+ E +RE EEE + QEE + E + K Sbjct: 686 IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQE 745 Query: 1003 ------KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052 + ++++ + E+ WEQQ EQ++K + E +++ EQ+ + + E Sbjct: 746 QEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEE 801 Score = 67.4 bits (163), Expect = 9e-11 Identities = 62/269 (23%), Positives = 125/269 (46%), Gaps = 23/269 (8%) Query: 890 VWDQEEERKRQER-WQKEQD-RLLQEKYQREQEKLREEWQRAKQEA--ERENSKYLDEEL 945 +W+QE+ ++++E+ W++E+ R +E + +E++ R+E R +++ E+E E+ Sbjct: 500 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 559 Query: 946 MVLSSNSMSLTTREPSLATW--EATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003 M M T+E TW E E + +RE EEE + QEE + E Q +K Sbjct: 560 MWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE-QEEK 618 Query: 1004 PQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP 1063 Q+Q E+ WEQ+ ++ QEQ+ E EE+ EE+ + + E +++++ + Sbjct: 619 MQEQ----EEKMWEQE-EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 673 Query: 1064 VDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKE 1123 + + + EE ++ K T+ + T +++ S + R KK Sbjct: 674 QEQEKMQEQEEKI-----WEQEKMEKKTQEQEKKTWDQ------EKMREEESMREREKKM 722 Query: 1124 QVPSGAELERQQILQEMRKRTPLHNDNSW 1152 + E+++ +QE ++ + W Sbjct: 723 REEEEMMREQEEKMQEQEEKMQEQEEEMW 751 Score = 65.5 bits (158), Expect = 3e-10 Identities = 67/287 (23%), Positives = 124/287 (43%), Gaps = 39/287 (13%) Query: 890 VWDQEEERKRQERWQK-------EQDRLLQEKYQR--EQEKLREEWQRAKQEAERENSKY 940 +W+QE++ + QE+ + EQD L+EK +R EQEK+ E+ ++ ++E + + + Sbjct: 378 LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEK 437 Query: 941 LDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ 1000 + +E + E K + E T +EE+ Q QEE + E + Sbjct: 438 KTRD-------------QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 484 Query: 1001 GKKPQDQ-LVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQ 1059 K+ Q Q L ++E+ WEQ+ +EQE+K E EE+ R EE Q + ++++ Sbjct: 485 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIW--EQEEKIRDQEEMWGQEK-------KMWR 535 Query: 1060 YRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQR- 1118 + + D +E + K E + T + K DQ M +R Sbjct: 536 QEKMREQEDQMWEQEEK---MRDQEQKMWDQEERMEKKTQEQ-EKKTWDQEEKMREEERM 591 Query: 1119 --RSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1163 R KK + E+++ +QE ++ + W ++ +E Sbjct: 592 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638 Score = 62.8 bits (151), Expect = 2e-09 Identities = 47/182 (25%), Positives = 86/182 (47%), Gaps = 23/182 (12%) Query: 891 WDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS 950 WDQE+ R+ + ++E+ +E+ REQE+ +E + QE E E + EE M Sbjct: 704 WDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEE--MWEQEEKMWEQE 761 Query: 951 NSMSLTTREPS----------LATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ 1000 M R P + E W + K D+E G+EE+ + QEE + + Sbjct: 762 EKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821 Query: 1001 GKK--PQDQLVIERERKWEQQL----QEEQEQKRLQAEAE-----EQKRPAEEQKRQAEI 1049 K ++++ + E+ W Q+ QEE+ ++++Q + E E+K +E+K + + Sbjct: 822 EKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQE 881 Query: 1050 ER 1051 E+ Sbjct: 882 EK 883 Score = 61.6 bits (148), Expect = 5e-09 Identities = 60/274 (21%), Positives = 117/274 (42%), Gaps = 31/274 (11%) Query: 892 DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAER--ENSKYLDEELMVLS 949 ++EE + QE+ ++ +++ +EK +EQEK + + QE ER E K + EE + Sbjct: 408 EKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMR 467 Query: 950 SNSMSLTTREPSLATWEAT---WSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQD 1006 + +E ++ WE W + +E + E+E+ Q QEE + E Q+ Sbjct: 468 EQEEKMQKQEENM--WEQEEKEWQQQRLPEQKE--KLWEQEKMQEQEEKIWE------QE 517 Query: 1007 QLVIERERKWEQQ----LQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRR 1062 + + ++E W Q+ QE+ ++ Q +E+K +EQK + ER Q ++ Sbjct: 518 EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKK 577 Query: 1063 PVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKK 1122 D + + EE R + R ++ + K +Q M Q + +K Sbjct: 578 TWDQEEKMREEE---------RMREREKKMREEEEMMREQEEKMQEQEEKM---QEQEEK 625 Query: 1123 EQVPSGAELERQQILQEMRKRTPLHNDNSWIRQR 1156 E+++ + E ++ + W +QR Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659 Score = 60.8 bits (146), Expect = 8e-09 Identities = 43/179 (24%), Positives = 87/179 (48%), Gaps = 23/179 (12%) Query: 890 VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREE----WQRAKQE--AERENSKYLDE 943 +W+QEE+ Q+R +++++L + + +EQEK++E+ W++ K E + + K D+ Sbjct: 647 MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ 706 Query: 944 ELMVLSSNSMSLTTREPSLATWEATWSEGS-KSSDREGTRAGEEERRQPQEEVVHEDQGK 1002 E M S+ RE + E E K ++E +EE QEE + E + K Sbjct: 707 EKM---REEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK 763 Query: 1003 KPQDQLVIER-------------ERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAE 1048 + Q + E+ E+ WEQ+ + ++++++ + E+ + E+ + Q E Sbjct: 764 MWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEE 822 Score = 57.0 bits (136), Expect = 1e-07 Identities = 60/302 (19%), Positives = 129/302 (42%), Gaps = 40/302 (13%) Query: 893 QEEERKRQE----RWQKEQDRLLQEKYQREQEKLRE----EWQRAK-----------QEA 933 QEEER R+ R ++E R +EK Q+++E + E EWQ+ + ++ Sbjct: 447 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 506 Query: 934 ERENSKYLDEELMVLSSNSM-----SLTTREPSLATWEATWSEGSKSSDREGTRAGEEER 988 + + K ++E + M + +E + W + K D+E +EER Sbjct: 507 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 566 Query: 989 ----RQPQEEVVHEDQGKKPQDQLVIERERKW--EQQLQEEQEQKRLQAEAEEQKRPAEE 1042 Q QE+ + + K +++ + ERE+K E+++ EQE+K +Q + E+ + E+ Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK-MQEQEEKMQEQEEK 625 Query: 1043 QKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNG 1102 Q E +E ++++ + + E+ LP + K ++ + + Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR---LPEQKEKLWEHEKMQEQEKMQEQ 682 Query: 1103 NNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKR-TPLHNDNSWIRQRSASVN 1161 K +Q + +EQ + E+ + + MR+R + + +R++ + Sbjct: 683 EEKIWEQ-----EKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQ 737 Query: 1162 KE 1163 ++ Sbjct: 738 EQ 739 Score = 55.8 bits (133), Expect = 3e-07 Identities = 38/144 (26%), Positives = 75/144 (52%), Gaps = 12/144 (8%) Query: 890 VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLS 949 +W+QEE+ Q+R +++++L + + +EQEK+ E+ ++ + + E+ + EE M Sbjct: 757 MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ---EEKMRGQ 813 Query: 950 SNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHED-QGKKPQDQL 1008 M E W + K +E G+EE+ QEE + E QG++ + + Sbjct: 814 EEKMR--------GQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMRE 865 Query: 1009 VIERERKWEQQLQEEQEQKRLQAE 1032 E+ R E++++E++E+ R Q E Sbjct: 866 QEEKMRGQEEKMREQEEKMRGQEE 889 Score = 40.0 bits (92), Expect = 0.015 Identities = 30/189 (15%), Positives = 89/189 (47%), Gaps = 14/189 (7%) Query: 380 QNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK-W--KDRRKSYTSDLQKKKEEREE--IEK 434 Q + R E+M++ + Q+ EQ++K +D K W ++R + T + +KK ++EE E+ Sbjct: 529 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREE 588 Query: 435 QALEKSKRSSKTFKEMLQDRE---SQNQKSTVPSRRRMYSFDDVLEE------GKRPPTM 485 + + + ++ + +EM++++E + ++ +M+ ++ ++E + Sbjct: 589 ERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMW 648 Query: 486 TVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSS 545 E ++ +R+ E+ ++ ++E+++ + ++ ++ +E+ Sbjct: 649 EQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEK 708 Query: 546 LRSRSTQME 554 +R + E Sbjct: 709 MREEESMRE 717 Score = 38.9 bits (89), Expect = 0.034 Identities = 28/148 (18%), Positives = 73/148 (49%), Gaps = 9/148 (6%) Query: 360 QKIYGENGSKSMSDVSAEDVQNLR---QLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRK 416 +K++ + + D E + +R Q +++ ++++ + +EQ++K D K ++ + Sbjct: 531 KKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEER 590 Query: 417 SYTSDLQKKKEE---REEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTV-PSRRRMYSF 472 + + ++EE RE+ EK ++ K + K Q+ + Q Q+ + +M+ Sbjct: 591 MREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQ 650 Query: 473 DDVLEEGKRPPTMTVSEASYQSERVEEK 500 ++ + E +R P E ++ E+++E+ Sbjct: 651 EEKMWEQQRLPEQ--KEKLWEHEKMQEQ 676 Score = 37.4 bits (85), Expect = 0.098 Identities = 30/162 (18%), Positives = 75/162 (46%), Gaps = 13/162 (8%) Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER--------EEIEKQALEK 439 E+MQ+ + ++ EQ++K +D W +K + + +++E++ + E++ ++ Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 563 Query: 440 SKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVL---EEGKRPPTMTVSEASYQSER 496 +R K +E Q++++ +Q+ + RM + + EE R + E + + Sbjct: 564 EERMEKKTQE--QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621 Query: 497 VEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQ 538 EEK ++ +++ + + E E ++ Q + EQ Sbjct: 622 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQ 663 Score = 36.2 bits (82), Expect = 0.22 Identities = 27/124 (21%), Positives = 59/124 (47%), Gaps = 13/124 (10%) Query: 389 EMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFK 448 E +K++ + +EQ++K D + K R + + +KK E EE+ ++ EK + + + Sbjct: 688 EQEKMEKKTQEQEKKTWD---QEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQ 744 Query: 449 EMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEI 508 E ++ Q +K M+ ++ + E +R P E ++ E+++E+ + E Sbjct: 745 EQEEEMWEQEEK--------MWEQEEKMWEQQRLPEQ--KEKLWEHEKMQEQEKIWEQEE 794 Query: 509 PKED 512 D Sbjct: 795 KMRD 798 Score = 35.8 bits (81), Expect = 0.29 Identities = 33/199 (16%), Positives = 91/199 (45%), Gaps = 9/199 (4%) Query: 328 LRKKKPDKHEDNRRSWASPV-YTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLR 386 LR+++ + + W E +G +K++ + K + + E + ++LR Sbjct: 281 LREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQE--KRLREQEKELREQEKELR 338 Query: 387 YE-EMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSK 445 + E+++ + Q++EQ++K + K +++ + + +++E E EKQ E+ ++ Sbjct: 339 EQKELREQEEQMQEQEEKMWEQEEKMREQEEK----MWRQEERLWEQEKQMREQEQKMRD 394 Query: 446 TFKEML-QDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATY 504 + M QD + ++ + + +M+ + + E K+ + + EE+ Sbjct: 395 QEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIRE 454 Query: 505 PSEIPKEDSTTFAKREDRV 523 + +E+ T ++E+++ Sbjct: 455 REKKMREEEETMREQEEKM 473 Score = 35.4 bits (80), Expect = 0.37 Identities = 28/165 (16%), Positives = 75/165 (45%), Gaps = 5/165 (3%) Query: 360 QKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQ-KWQDDLAKWKDRRKSY 418 +K+ E + E+ + +R+ + E+MQ+ + +++EQ++ W+ + + K + Sbjct: 583 EKMREEERMREREKKMREEEEMMRE-QEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMW 641 Query: 419 TSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEE 478 + + ++E + E+Q L + K ++M + + Q Q+ + + +M + +E Sbjct: 642 EQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKM---EKKTQE 698 Query: 479 GKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRV 523 ++ +S R EK E+ +E ++E+++ Sbjct: 699 QEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKM 743 Score = 35.4 bits (80), Expect = 0.37 Identities = 14/46 (30%), Positives = 32/46 (69%) Query: 890 VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAER 935 +W QEE+ + + + Q+E+ R +EK + ++EK+RE+ ++ + + E+ Sbjct: 845 MWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890 Score = 34.7 bits (78), Expect = 0.64 Identities = 31/155 (20%), Positives = 74/155 (47%), Gaps = 11/155 (7%) Query: 388 EEMQKIKSQLKEQDQKWQDDLAK-WKDRRKSYTSDLQKKKEER--EEIEKQALEKSKRSS 444 E + + + Q++EQ+QK +D + W+ + + + +++E+ E++EK EK K Sbjct: 376 ERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEK-KMQE 434 Query: 445 KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEE-----GKRPPTM-TVSEASYQSERV- 497 + K Q+ + Q ++ ++M ++ + E K+ M E +Q +R+ Sbjct: 435 QEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 494 Query: 498 EEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQ 532 E+K + E +E ++E+++ + ++ Q Sbjct: 495 EQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ 529 Score = 34.7 bits (78), Expect = 0.64 Identities = 18/124 (14%), Positives = 62/124 (50%), Gaps = 1/124 (0%) Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQA 436 E Q +R + E M + +L+E++++ ++ W+ K +++E++ +++ Sbjct: 387 EQEQKMRD-QEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEK 445 Query: 437 LEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSER 496 +++ +R + K+M ++ E+ ++ ++ ++ +E ++ E ++ E+ Sbjct: 446 MQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 505 Query: 497 VEEK 500 ++E+ Sbjct: 506 MQEQ 509 Score = 33.5 bits (75), Expect = 1.4 Identities = 19/95 (20%), Positives = 53/95 (55%), Gaps = 4/95 (4%) Query: 388 EEMQKIKSQLKEQDQK---WQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 444 EEM + + +L+EQ++K ++ + + ++R + +++++E+ EK+ E+ K Sbjct: 272 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELR 331 Query: 445 KTFKEMLQDRESQNQKSTVPSR-RRMYSFDDVLEE 478 + KE+ + +E + Q+ + + +M+ ++ + E Sbjct: 332 EQEKELREQKELREQEEQMQEQEEKMWEQEEKMRE 366 Score = 33.5 bits (75), Expect = 1.4 Identities = 24/161 (14%), Positives = 77/161 (47%), Gaps = 11/161 (6%) Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQK--------WQDDLAKWKDRRKSYTSDLQKKKEE 428 ++ + +R+ R ++M++ + ++EQ++K W+ + +W+ +R + ++E+ Sbjct: 447 QEEERIRE-REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEK 505 Query: 429 REEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVS 488 +E E++ E+ ++ + Q+++ Q+ +M+ ++ + + ++ M Sbjct: 506 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ--KMWDQ 563 Query: 489 EASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQL 529 E + + E++ T+ E + +RE ++ E ++ Sbjct: 564 EERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEM 604 Score = 33.1 bits (74), Expect = 1.9 Identities = 31/173 (17%), Positives = 73/173 (42%), Gaps = 10/173 (5%) Query: 330 KKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEE 389 K + E +++W E + R E + ++ E + +++ + E+ Sbjct: 691 KMEKKTQEQEKKTWDQEKMREEESMRER-------EKKMREEEEMMREQEEKMQE-QEEK 742 Query: 390 MQKIKSQLKEQDQK-WQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFK 448 MQ+ + ++ EQ++K W+ + W+ +R + + E+ +E EK ++ K + K Sbjct: 743 MQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEK 802 Query: 449 EMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASY-QSERVEEK 500 Q+ + + Q+ + + + G+ E + Q E++EEK Sbjct: 803 MRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEK 855 Score = 32.0 bits (71), Expect = 4.1 Identities = 31/162 (19%), Positives = 79/162 (48%), Gaps = 36/162 (22%) Query: 388 EEMQKIKSQLKEQDQK-WQDDLAKWKDRRKSYTSD-------------LQKKKE---ERE 430 E+MQ+ + ++ EQ++K W+ + W+ +R + +Q+++E E+E Sbjct: 631 EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQE 690 Query: 431 EIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEA 490 ++EK+ E+ K++ +E +++ ES ++ ++M ++++ E + + Sbjct: 691 KMEKKTQEQEKKTWD--QEKMREEESMRER-----EKKMREEEEMMREQE-------EKM 736 Query: 491 SYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQ 532 Q E+++E+ E E ++E+++ + +LP Q Sbjct: 737 QEQEEKMQEQ-----EEEMWEQEEKMWEQEEKMWEQQRLPEQ 773 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 75.5 bits (184), Expect = 3e-13 Identities = 66/321 (20%), Positives = 133/321 (41%), Gaps = 24/321 (7%) Query: 890 VWDQEEERKRQERWQKEQDRLL--QEKYQREQEKLREEWQRAKQEAERENSKYLDEELMV 947 +W QEE+ + QE +EQ++ + QE+ EQEK+REE +R +QE + + E+ + Sbjct: 432 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491 Query: 948 LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQ 1007 E E W + K ++E +EE+ QEE + E + +++ Sbjct: 492 WRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551 Query: 1008 LVIERERKWEQQLQEEQEQK------RLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYR 1061 + E+E+ WE++ ++EQE K +++ + E+ R E+ + Q E +E ++++ Sbjct: 552 KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE 611 Query: 1062 RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNG--NNKYLDQIGNMTSSQ-- 1117 + + E+ + K R E+ K G K +Q M + Sbjct: 612 EKIREQEEKIQEQEEK--IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET 669 Query: 1118 --RRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGE 1175 R+ +K + E+++ ++E + + W ++ +E + E Sbjct: 670 MWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ--------E 721 Query: 1176 SLDNLDSPRSNSWRQPPWLNQ 1196 + + W Q L Q Sbjct: 722 QEEKMRRQEEKMWEQEVRLRQ 742 Score = 69.7 bits (169), Expect = 2e-11 Identities = 52/179 (29%), Positives = 90/179 (50%), Gaps = 14/179 (7%) Query: 890 VWDQEEERKRQER--WQKEQDRLLQEKYQREQEKLRE-EWQRAKQEAERENSKYLDEELM 946 +W++EE+ +RQE W+KE+ E+ EQEK+RE E +R ++E RE K ++E Sbjct: 372 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 431 Query: 947 VLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQD 1006 + E + W + K ++E R EEE+RQ QEE+ Q+ Sbjct: 432 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR--EEEKRQEQEEMWR-------QE 482 Query: 1007 QLVIERERKWEQ-QLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPV 1064 + + E+E W Q + EQE+K ++ + E+ R E+ + Q E RE ++++ + Sbjct: 483 EKIHEQEEIWRQKEKMHEQEEK-IRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540 Score = 68.9 bits (167), Expect = 3e-11 Identities = 49/192 (25%), Positives = 101/192 (52%), Gaps = 14/192 (7%) Query: 890 VWDQEEERKRQER-W-QKEQDRLLQEKYQREQEKLREEWQRAKQEAE---RENSKYLDEE 944 +W++E+ ++++++ W Q+E+ R +EK R++EK+RE+ ++ +++ E ++ K ++E Sbjct: 559 IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618 Query: 945 LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-K 1003 + E E T + K ++E +EE+ Q QEE + + K + Sbjct: 619 EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678 Query: 1004 PQDQLVIERE---RKWEQQLQEEQ----EQKRLQAEAEEQKRPAEEQ-KRQAEIERETSV 1055 Q++ + E+E R+ E+ +QE++ EQ+ E EE+ + EE+ +RQ E E V Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738 Query: 1056 RIYQYRRPVDSY 1067 R+ Q + + Sbjct: 739 RLRQQEEKMQEH 750 Score = 65.5 bits (158), Expect = 3e-10 Identities = 55/235 (23%), Positives = 116/235 (49%), Gaps = 20/235 (8%) Query: 832 ESKEING-IHDESNAFESKASE-SISLKNLKRRSQFFE--------QGSSDSVVPDLPVP 881 E KE N + ++ ES+ SE +++K LKR+ + + Q +D + +L Sbjct: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277 Query: 882 TISAPSRW----VWDQEEERKRQERW-QKEQDRLLQEKYQREQEKLREEWQRAKQEAE-- 934 + ++ +W++ +++ ++ W Q+E+ + +EK Q ++EK+RE+ ++ +++ E Sbjct: 278 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337 Query: 935 -RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE 993 R+ ++E + M E E W + K +E +EE+ + E Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 397 Query: 994 EVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQK--RLQAEAEEQKRPAEEQKRQ 1046 E +HE + + Q++ E E+ EQ+ ++EQE K R + + EQ+ EQ+++ Sbjct: 398 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452 Score = 56.2 bits (134), Expect = 2e-07 Identities = 44/162 (27%), Positives = 84/162 (51%), Gaps = 15/162 (9%) Query: 892 DQEEERKRQER--WQKEQDRLLQEKYQREQEKL--REEWQRAKQEAERENSKYLDEELMV 947 +QEE+ +RQE W+KE EK +R++E + +EE R ++E E + + + + Sbjct: 332 EQEEKMRRQEEMMWEKE------EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 385 Query: 948 LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQD 1006 + + E + E + K + E R E+E+RQ QE + + K + Q+ Sbjct: 386 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR--EQEKRQEQEAKMWRQEEKIREQE 443 Query: 1007 QLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAE 1048 + + E+E+K +Q ++ EQ++++ EE+++ EE RQ E Sbjct: 444 EKIREQEKKMWRQEEKIHEQEKIR--EEEKRQEQEEMWRQEE 483 Score = 38.9 bits (89), Expect = 0.034 Identities = 29/176 (16%), Positives = 79/176 (44%), Gaps = 7/176 (3%) Query: 331 KKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEM 390 ++ +K + + W E + R +KI + + + + RQ + E+M Sbjct: 548 REEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKM 607 Query: 391 QKIKSQLKEQDQKWQDDLAKWKDR------RKSYTSDLQKKKEEREEIEKQALEKSKRSS 444 K + +++EQ++K Q+ K +++ ++ T + ++K E+EE + EK + Sbjct: 608 WKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQE 667 Query: 445 KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 500 +T +++ + +K ++ +++++E + + Q E+++E+ Sbjct: 668 ETMWRQ-EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 722 Score = 37.0 bits (84), Expect = 0.13 Identities = 30/159 (18%), Positives = 70/159 (44%), Gaps = 9/159 (5%) Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEERE---EIE 433 E + ++R EE ++ + ++ Q++K + W+ + K + + + +K+E + + E Sbjct: 458 EKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEE 517 Query: 434 KQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQ 493 K ++ K + K Q+ + + Q+ +M+ + + EE KR E + Sbjct: 518 KIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKR------QEQEDK 571 Query: 494 SERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQ 532 R EEK ++ +++ + E R E ++ Q Sbjct: 572 MWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQ 610 Score = 35.0 bits (79), Expect = 0.49 Identities = 33/174 (18%), Positives = 83/174 (47%), Gaps = 17/174 (9%) Query: 377 EDVQNLRQLRYEEMQKIKSQ---LKEQDQKW--QDDLAKWKDRRKSYTSDLQKKKEEREE 431 E +Q + E+ +KI+ Q ++EQ++K Q+++ K+ + ++ +KEE+ Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366 Query: 432 IEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLE-EGKRPPTMTVSEA 490 +++ + + + + +EM+ ++E + ++ +M+ + + E E KR + E Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRE----LEEKMHEQEKIREQEEKRQEEEKIREQ 422 Query: 491 SYQSE------RVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQ 538 + E R EEK +I +E ++E+++ + ++ + +EQ Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKI-REQEKKMWRQEEKIHEQEKIREEEKRQEQ 475 Score = 34.3 bits (77), Expect = 0.83 Identities = 29/149 (19%), Positives = 67/149 (44%), Gaps = 14/149 (9%) Query: 386 RYEEM--QKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRS 443 R EEM +K + ++++ W+ + + K + + +++EE+ + E++ E+ KR Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQ 426 Query: 444 SKTFKEMLQDRESQNQKSTVPSR--------RRMYSFDDVLEEGKRPPTMTVSEASYQSE 495 + K Q+ + + Q+ + + +++ + + EE KR E Q E Sbjct: 427 EQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR---QEQEEMWRQEE 483 Query: 496 RVEEKGATY-PSEIPKEDSTTFAKREDRV 523 ++ E+ + E E K+E++V Sbjct: 484 KIHEQEEIWRQKEKMHEQEEKIRKQEEKV 512 Score = 34.3 bits (77), Expect = 0.83 Identities = 28/153 (18%), Positives = 72/153 (47%), Gaps = 23/153 (15%) Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK------WKDRRKSYTSDLQKKKEERE 430 E + +R+ + E+M + + +++EQ++ W+++ W++ ++ D ++EE+ Sbjct: 521 EQEEKIRE-QEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEK- 578 Query: 431 EIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEA 490 I +Q EK R + +E + R+ Q +K M+ ++ + E + + Sbjct: 579 -IREQE-EKVWRQEEKIREQEEKRQEQEEK--------MWKQEEKIREQEEKIQEQEEKI 628 Query: 491 SYQSERVEEKGATYPSEIPKEDSTTFAKREDRV 523 Q E++ E+ E+ +E ++E+++ Sbjct: 629 REQEEKIREQ-----EEMTQEQEEKMGEQEEKM 656 Score = 33.1 bits (74), Expect = 1.9 Identities = 31/198 (15%), Positives = 84/198 (42%), Gaps = 7/198 (3%) Query: 334 DKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDV----QNLRQLRYEE 389 +K E RR + E + L +K++ + + + E+ Q RQ + + Sbjct: 374 EKEEKMRRQ--EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 431 Query: 390 MQKIKSQLKEQDQKWQDDLAK-WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFK 448 M + + +++EQ++K ++ K W+ K + + +++E+R+E E+ ++ K + Sbjct: 432 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491 Query: 449 EMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEI 508 +++ + ++ +++ ++ + E + + Q E++ E+ + E Sbjct: 492 WRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551 Query: 509 PKEDSTTFAKREDRVTTE 526 + + E R E Sbjct: 552 KMHEQEKIWEEEKRQEQE 569 Score = 32.7 bits (73), Expect = 2.4 Identities = 24/136 (17%), Positives = 63/136 (46%), Gaps = 12/136 (8%) Query: 377 EDVQNLRQLRYEEMQKIKSQ----------LKEQDQKWQDDLAK-WKDRRKSYTSDLQKK 425 E++ ++ +E+ +KI+ Q ++EQ++K ++ K W+ K + + Sbjct: 489 EEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWR 548 Query: 426 KEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTV-PSRRRMYSFDDVLEEGKRPPT 484 +EE+ +++ E+ KR + K Q+ + + Q+ V ++ ++ +E + Sbjct: 549 EEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMW 608 Query: 485 MTVSEASYQSERVEEK 500 + Q E+++E+ Sbjct: 609 KQEEKIREQEEKIQEQ 624 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 73.9 bits (180), Expect = 9e-13 Identities = 46/189 (24%), Positives = 94/189 (49%), Gaps = 11/189 (5%) Query: 892 DQEEERKRQERWQKEQDRLLQEKYQ---REQEKLREEWQRAKQEAERENSKYLDEELMVL 948 +QEE+ RQE +EQD +QE+ + R++EK+RE+ ++ +++ R+ K +++ + Sbjct: 364 EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423 Query: 949 SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKP---- 1004 E E + K + E EEE+ Q QEE + + K Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE 483 Query: 1005 ----QDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQY 1060 Q++L+ + E+ WEQ+ + ++++++ + E+ + E+ +RQ E RE VR++Q Sbjct: 484 KTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQ 543 Query: 1061 RRPVDSYDI 1069 + ++ Sbjct: 544 EEKMQEQEV 552 Score = 56.2 bits (134), Expect = 2e-07 Identities = 39/178 (21%), Positives = 93/178 (52%), Gaps = 17/178 (9%) Query: 890 VWDQEEERKRQERWQKEQD---RLLQEKYQREQEKLREEWQRAKQEAE---RENSKYLDE 943 +W QEE+ + QE EQ+ R +EK R++EK+ E+ ++ +++ + R+ K ++ Sbjct: 299 MWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ 358 Query: 944 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003 E + + +E + + E + R+ + E+E ++ QE++ +++ + Sbjct: 359 EEKIREQEE-KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKR-QEKMWRQEKKMR 416 Query: 1004 PQDQLVIERERK-WEQ--------QLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052 QD+ + E+E + W Q ++ ++QE+K + E + Q+ + Q+++ +I+R+ Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474 Score = 56.2 bits (134), Expect = 2e-07 Identities = 52/204 (25%), Positives = 103/204 (50%), Gaps = 19/204 (9%) Query: 892 DQEEERK----RQERWQKEQDRLLQEKYQ---REQEKLRE--EWQRAKQEAERENSKYLD 942 +QEE+R+ RQE+ +EQD ++E+ + R++EK+RE E + ++E RE + + Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458 Query: 943 EELMVLSSNSMSLTTREPSLATWEA-TW------SEGSKSSDREGTRAGEEERRQPQEEV 995 EE + + +E + E TW + K ++E +EE+ QEE Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518 Query: 996 VHEDQGK-KPQDQLVIERE-RKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1053 + E + K + Q++ + E+E R W+Q+ + ++++ RLQ E + ++ + RE+ Sbjct: 519 MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRES 578 Query: 1054 SVRIYQYRRPVDSYDIPKTEEASS 1077 + P+ ++ K++EA S Sbjct: 579 GSQRLPTLTPILQVEL-KSQEAQS 601 Score = 48.5 bits (114), Expect = 4e-05 Identities = 58/233 (24%), Positives = 105/233 (45%), Gaps = 31/233 (13%) Query: 832 ESKEING-IHDESNAFESKASE-SISLKNLKR---RSQFFEQGSSDSVVPDLPVPTISAP 886 E KE N + ++ ES+ SE +++K+LKR R+Q V D + + Sbjct: 215 ELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSV 274 Query: 887 SRWVWDQEEERKRQERWQKEQDRLL---QEKYQREQEKLREEWQRAKQEAERENSKYLDE 943 S + Q EE + ++Q+ + +EK Q ++EK+ E+ + + E+E + E Sbjct: 275 SAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR---EQEEKMWRQE 331 Query: 944 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003 E M + RE W E R EE+ R+ +E++ +++ + Sbjct: 332 EKM----HEQEEKIREQEDKMWR----------QEEKIREQEEKIREQEEKMWRQEEKIR 377 Query: 1004 PQDQLVIERERKWEQQLQE----EQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052 QD+ + E+E E QE EQE+KR + ++K+ E+ ++ E E E Sbjct: 378 EQDEKIQEQEE--EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE 428 Score = 41.2 bits (95), Expect = 0.007 Identities = 22/54 (40%), Positives = 36/54 (66%), Gaps = 7/54 (12%) Query: 890 VWDQEEERKRQER--WQKEQDRLLQ-EKYQREQEKLREE----WQRAKQEAERE 936 +W+QEE+ RQE W++E+ Q EK QR++EK+RE+ WQ+ ++ E+E Sbjct: 498 IWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551 Score = 35.8 bits (81), Expect = 0.29 Identities = 32/188 (17%), Positives = 81/188 (43%), Gaps = 3/188 (1%) Query: 368 SKSMSDVSAEDVQNL-RQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKK 426 +K + V ++ NL Q + E+M + + +++EQ++K + K +++ + +K Sbjct: 276 AKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMH 335 Query: 427 EEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMT 486 E+ E+I +Q +K R + +E + Q +K ++ D+ ++E + Sbjct: 336 EQEEKIREQE-DKMWRQEEKIREQEEKIREQEEKMW-RQEEKIREQDEKIQEQEEEMWRQ 393 Query: 487 VSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSL 546 + Q E+ +EK ++ ++D + E+ E ++ + + L + Sbjct: 394 EEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREV 453 Query: 547 RSRSTQME 554 + + E Sbjct: 454 EEKMQEEE 461 Score = 35.8 bits (81), Expect = 0.29 Identities = 20/113 (17%), Positives = 57/113 (50%), Gaps = 3/113 (2%) Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447 EEM + + +++E ++ QD K ++ + + +K +E+ E+I++Q + ++ KT+ Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486 Query: 448 KEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 500 + Q++ + ++ +M+ ++ + E + + Q E++ E+ Sbjct: 487 R---QEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQ 536 Score = 32.0 bits (71), Expect = 4.1 Identities = 18/89 (20%), Positives = 49/89 (55%), Gaps = 6/89 (6%) Query: 377 EDVQNLRQLRYEEMQKIKSQ---LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIE 433 E +Q + E+ +K Q LK++++ W+ + W+ K + + +K +E+ E+++ Sbjct: 469 EKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE-EKMQEQEEKMQ 527 Query: 434 KQALEKSKRSSKTF--KEMLQDRESQNQK 460 +Q + ++ + + +E +Q++E + Q+ Sbjct: 528 RQEEKMREQEVRLWQQEEKMQEQEVRLQE 556 >gi|239745127 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 73.9 bits (180), Expect = 9e-13 Identities = 46/189 (24%), Positives = 94/189 (49%), Gaps = 11/189 (5%) Query: 892 DQEEERKRQERWQKEQDRLLQEKYQ---REQEKLREEWQRAKQEAERENSKYLDEELMVL 948 +QEE+ RQE +EQD +QE+ + R++EK+RE+ ++ +++ R+ K +++ + Sbjct: 364 EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423 Query: 949 SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKP---- 1004 E E + K + E EEE+ Q QEE + + K Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE 483 Query: 1005 ----QDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQY 1060 Q++L+ + E+ WEQ+ + ++++++ + E+ + E+ +RQ E RE VR++Q Sbjct: 484 KTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQ 543 Query: 1061 RRPVDSYDI 1069 + ++ Sbjct: 544 EEKMQEQEV 552 Score = 56.2 bits (134), Expect = 2e-07 Identities = 39/178 (21%), Positives = 93/178 (52%), Gaps = 17/178 (9%) Query: 890 VWDQEEERKRQERWQKEQD---RLLQEKYQREQEKLREEWQRAKQEAE---RENSKYLDE 943 +W QEE+ + QE EQ+ R +EK R++EK+ E+ ++ +++ + R+ K ++ Sbjct: 299 MWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ 358 Query: 944 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003 E + + +E + + E + R+ + E+E ++ QE++ +++ + Sbjct: 359 EEKIREQEE-KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKR-QEKMWRQEKKMR 416 Query: 1004 PQDQLVIERERK-WEQ--------QLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052 QD+ + E+E + W Q ++ ++QE+K + E + Q+ + Q+++ +I+R+ Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474 Score = 56.2 bits (134), Expect = 2e-07 Identities = 52/204 (25%), Positives = 103/204 (50%), Gaps = 19/204 (9%) Query: 892 DQEEERK----RQERWQKEQDRLLQEKYQ---REQEKLRE--EWQRAKQEAERENSKYLD 942 +QEE+R+ RQE+ +EQD ++E+ + R++EK+RE E + ++E RE + + Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458 Query: 943 EELMVLSSNSMSLTTREPSLATWEA-TW------SEGSKSSDREGTRAGEEERRQPQEEV 995 EE + + +E + E TW + K ++E +EE+ QEE Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518 Query: 996 VHEDQGK-KPQDQLVIERE-RKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1053 + E + K + Q++ + E+E R W+Q+ + ++++ RLQ E + ++ + RE+ Sbjct: 519 MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRES 578 Query: 1054 SVRIYQYRRPVDSYDIPKTEEASS 1077 + P+ ++ K++EA S Sbjct: 579 GSQRLPTLTPILQVEL-KSQEAQS 601 Score = 48.5 bits (114), Expect = 4e-05 Identities = 58/233 (24%), Positives = 105/233 (45%), Gaps = 31/233 (13%) Query: 832 ESKEING-IHDESNAFESKASE-SISLKNLKR---RSQFFEQGSSDSVVPDLPVPTISAP 886 E KE N + ++ ES+ SE +++K+LKR R+Q V D + + Sbjct: 215 ELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSV 274 Query: 887 SRWVWDQEEERKRQERWQKEQDRLL---QEKYQREQEKLREEWQRAKQEAERENSKYLDE 943 S + Q EE + ++Q+ + +EK Q ++EK+ E+ + + E+E + E Sbjct: 275 SAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR---EQEEKMWRQE 331 Query: 944 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003 E M + RE W E R EE+ R+ +E++ +++ + Sbjct: 332 EKM----HEQEEKIREQEDKMWR----------QEEKIREQEEKIREQEEKMWRQEEKIR 377 Query: 1004 PQDQLVIERERKWEQQLQE----EQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052 QD+ + E+E E QE EQE+KR + ++K+ E+ ++ E E E Sbjct: 378 EQDEKIQEQEE--EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE 428 Score = 41.2 bits (95), Expect = 0.007 Identities = 22/54 (40%), Positives = 36/54 (66%), Gaps = 7/54 (12%) Query: 890 VWDQEEERKRQER--WQKEQDRLLQ-EKYQREQEKLREE----WQRAKQEAERE 936 +W+QEE+ RQE W++E+ Q EK QR++EK+RE+ WQ+ ++ E+E Sbjct: 498 IWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551 Score = 35.8 bits (81), Expect = 0.29 Identities = 32/188 (17%), Positives = 81/188 (43%), Gaps = 3/188 (1%) Query: 368 SKSMSDVSAEDVQNL-RQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKK 426 +K + V ++ NL Q + E+M + + +++EQ++K + K +++ + +K Sbjct: 276 AKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMH 335 Query: 427 EEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMT 486 E+ E+I +Q +K R + +E + Q +K ++ D+ ++E + Sbjct: 336 EQEEKIREQE-DKMWRQEEKIREQEEKIREQEEKMW-RQEEKIREQDEKIQEQEEEMWRQ 393 Query: 487 VSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSL 546 + Q E+ +EK ++ ++D + E+ E ++ + + L + Sbjct: 394 EEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREV 453 Query: 547 RSRSTQME 554 + + E Sbjct: 454 EEKMQEEE 461 Score = 35.8 bits (81), Expect = 0.29 Identities = 20/113 (17%), Positives = 57/113 (50%), Gaps = 3/113 (2%) Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447 EEM + + +++E ++ QD K ++ + + +K +E+ E+I++Q + ++ KT+ Sbjct: 427 EEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTW 486 Query: 448 KEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 500 + Q++ + ++ +M+ ++ + E + + Q E++ E+ Sbjct: 487 R---QEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQ 536 Score = 32.0 bits (71), Expect = 4.1 Identities = 18/89 (20%), Positives = 49/89 (55%), Gaps = 6/89 (6%) Query: 377 EDVQNLRQLRYEEMQKIKSQ---LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIE 433 E +Q + E+ +K Q LK++++ W+ + W+ K + + +K +E+ E+++ Sbjct: 469 EKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQE-EKMQEQEEKMQ 527 Query: 434 KQALEKSKRSSKTF--KEMLQDRESQNQK 460 +Q + ++ + + +E +Q++E + Q+ Sbjct: 528 RQEEKMREQEVRLWQQEEKMQEQEVRLQE 556 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 73.6 bits (179), Expect = 1e-12 Identities = 48/186 (25%), Positives = 93/186 (50%), Gaps = 8/186 (4%) Query: 890 VWDQEEERKRQERWQKEQDRLLQEKYQR---EQEKL---REEWQRAKQEAERENSKYLDE 943 +W QEE+ + QE +EQ+ ++QE+ ++ ++EK+ EE Q +++ R+ K ++ Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ 444 Query: 944 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK- 1002 E + E E + K ++E +EE+ + QEE + E + K Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKI 504 Query: 1003 KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQ-KRQAEIERETSVRIYQYR 1061 + Q++ + E+E ++Q ++ EQ+ E EE+ + EE+ +RQ E RE VR+ Q Sbjct: 505 REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQE 564 Query: 1062 RPVDSY 1067 + + Sbjct: 565 EKMQEH 570 Score = 70.9 bits (172), Expect = 8e-12 Identities = 49/188 (26%), Positives = 92/188 (48%), Gaps = 21/188 (11%) Query: 890 VWDQEEERKRQER--WQKEQDRLLQEKYQREQEKLREEWQRAKQEAE------------- 934 +W++EE+ +RQE W+KE+ E+ EQEK+RE+ ++ ++E + Sbjct: 325 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384 Query: 935 --RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQ 992 R+ K ++E + M E E W + + ++E +EE+ + Q Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ 444 Query: 993 EEVVHEDQGK-KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAE--- 1048 E+ + E + K + Q++++ E+E K +Q + EQ+ E EE+ R EE+ R+ E Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKI 504 Query: 1049 IERETSVR 1056 E+E +R Sbjct: 505 REQEEKIR 512 Score = 63.9 bits (154), Expect = 1e-09 Identities = 47/184 (25%), Positives = 92/184 (50%), Gaps = 25/184 (13%) Query: 890 VWDQEEERKRQERWQKEQDRLL-QEKYQREQEKLREEWQRAKQEAE--RENSKYLDEELM 946 +W++EE+ + E EQ+++ QE+ ++E+EK+RE+ +R +QEA+ R+ K ++E Sbjct: 339 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 398 Query: 947 VLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQ 1005 + M E E W + + ++E +EE+ + QE+ + E + K + Q Sbjct: 399 IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 458 Query: 1006 DQLVIERERKW-------------------EQQLQEE--QEQKRLQAEAEEQKRPAEEQK 1044 ++++ E+E K + + QEE +EQ++ E EE+ R EE Sbjct: 459 EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 518 Query: 1045 RQAE 1048 ++ E Sbjct: 519 QEQE 522 Score = 62.4 bits (150), Expect = 3e-09 Identities = 60/254 (23%), Positives = 124/254 (48%), Gaps = 25/254 (9%) Query: 832 ESKEING-IHDESNAFESKASE-SISLKNLKRRSQFFE--------QGSSDSVVPDLPVP 881 E KE N + ++ ES+ SE +++K LKR+ + + Q +D + +L Sbjct: 206 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 265 Query: 882 TISAPSRW----VWDQEEERKRQERW-QKEQDRLLQEKYQREQEKLREEWQRAKQEAE-- 934 + ++ +W++ +++ ++ W Q+E+ + +EK Q ++EK+RE+ ++ +++ E Sbjct: 266 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMM 325 Query: 935 --RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQ 992 +E EE+M + E + E + K + E R E+E+RQ Q Sbjct: 326 WEKEEKMRRQEEMMW--EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR--EQEKRQEQ 381 Query: 993 EEVVHEDQGK-KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQ-KRQAEIE 1050 E + + K + Q++ + E+E ++Q ++ EQ+ E EE+ + EE+ +RQ E Sbjct: 382 EAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKI 441 Query: 1051 RETSVRIYQYRRPV 1064 RE +I + + Sbjct: 442 REQEKKIREQEEKI 455 Score = 35.0 bits (79), Expect = 0.49 Identities = 28/152 (18%), Positives = 70/152 (46%), Gaps = 6/152 (3%) Query: 380 QNLRQLRYEEM--QKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQAL 437 Q + R EEM +K + ++++ W+ + + K + + +++EE+ + E++ Sbjct: 314 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 373 Query: 438 EKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERV 497 E+ KR + K Q+ + + Q+ + + M + + G++ M E Q + Sbjct: 374 EQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQ-EQEEKMGEQEEKMWEQEEEMQEQ-- 430 Query: 498 EEKGATYPSEIPKEDSTTFAKREDRVTTEIQL 529 EEK +I +E ++E+++ + ++ Sbjct: 431 EEKMRRQEEKI-REQEKKIREQEEKIREQEEM 461 Score = 32.3 bits (72), Expect = 3.2 Identities = 26/147 (17%), Positives = 67/147 (45%), Gaps = 3/147 (2%) Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447 E+M + + +++EQ++K + K +++ K +K +E+ E +++Q + ++ K Sbjct: 418 EKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMC 477 Query: 448 KE--MLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYP 505 ++ +Q++E + ++ R + + EE R + E + EEK Sbjct: 478 EQEAKMQEQEEKMRRQEEKIREQEKKIRE-QEEKIREQEEMMQEQEEKMWEQEEKMCEQE 536 Query: 506 SEIPKEDSTTFAKREDRVTTEIQLPSQ 532 ++ +++ + E E++L Q Sbjct: 537 EKMQEQEEKMRRQEEKMREQEVRLRQQ 563 Score = 32.0 bits (71), Expect = 4.1 Identities = 23/121 (19%), Positives = 56/121 (46%), Gaps = 2/121 (1%) Query: 350 EADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLA 409 E + R +KI + + + + + Q + E+M + + ++ EQ+ K Q+ Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488 Query: 410 KWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF--KEMLQDRESQNQKSTVPSRR 467 K + + + +K +E+ E+I +Q ++ K + +E + ++E + Q+ RR Sbjct: 489 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 548 Query: 468 R 468 + Sbjct: 549 Q 549 Score = 31.2 bits (69), Expect = 7.0 Identities = 23/120 (19%), Positives = 59/120 (49%), Gaps = 8/120 (6%) Query: 384 QLRYEEMQKIKSQLKEQDQKW--QDDLAKWKDRRKSYTSDLQKKKEER-EEIEKQALEKS 440 Q R E++Q+ + +++EQ++K Q+++ K+ + ++ +KEE+ E+E++ E+ Sbjct: 298 QEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 357 Query: 441 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 500 K + K +++ + +K + + + E+ ++ + E + EEK Sbjct: 358 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK-----IREQEEMMQEQEEK 412 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 73.2 bits (178), Expect = 2e-12 Identities = 75/332 (22%), Positives = 153/332 (46%), Gaps = 44/332 (13%) Query: 761 KFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEK---SSNLS 817 KF + E ++ + + H +++R A S K D E+ S L Sbjct: 117 KFEDGNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELY 176 Query: 818 VTTDFSESLQSSNIESKEINGIHDESNAFESKASE-SISLKNLKRRSQFFEQGSSDSVVP 876 T +E L+ N E +E + ES+ SE +++K LKR+ + + ++P Sbjct: 177 RNTITNEELKKKNAELQE------KLRLAESEKSEIQLNVKELKRKLE-----RAKFLLP 225 Query: 877 DLPVPTISAPSRWVWDQEEE--------RKRQERWQKEQDRLLQ---------EKYQREQ 919 + T+ +W QEEE RK++E+ ++++RL + EK +R++ Sbjct: 226 QVQTNTLQEE---MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQE 282 Query: 920 EKLREEWQRAKQEAE--RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSD 977 ++LRE+ + +++ + RE K ++E + E E W + + + Sbjct: 283 KRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWE 342 Query: 978 REGTRAGEEERRQPQEEVVHE-DQGKKPQDQLVIERERKWEQQ--LQEE----QEQKRLQ 1030 +E +E++ + QEE + E D+ + +++ + E+E+ WEQ+ +QEE + +K+++ Sbjct: 343 QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMR 402 Query: 1031 AEAEEQKRPAEEQKRQAEIERETSVRIYQYRR 1062 E E + E+ ++Q E E + +Q +R Sbjct: 403 EEEETMREQEEKMQKQEENMWEQEEKEWQQQR 434 Score = 66.6 bits (161), Expect = 2e-10 Identities = 59/212 (27%), Positives = 99/212 (46%), Gaps = 36/212 (16%) Query: 891 WDQEE---------ERKRQERWQKEQDRLLQEKYQREQEKLREE----WQRAKQEAEREN 937 WDQEE ER+++ R ++E R +EK Q ++EK+RE+ W++ ++ E+E Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609 Query: 938 SKYLDEELM--------VLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERR 989 + EE M + M E E W + K ++E +EE+ Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 669 Query: 990 QPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAE---AEEQKRPAEEQKRQ 1046 Q QEE + E Q +K Q Q E++++E++E+ R Q E +E+K +E+K Sbjct: 670 QGQEEKMRE-QEEKMQGQ---------EEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMW 719 Query: 1047 AEIE-RETSVRIYQYRRPVDSYDIPKTEEASS 1077 + E RE RI + + +P+ EE S Sbjct: 720 GQEEMREKEERIRDQKEKMQE-RLPEHEERCS 750 Score = 66.2 bits (160), Expect = 2e-10 Identities = 49/267 (18%), Positives = 121/267 (45%), Gaps = 24/267 (8%) Query: 890 VWDQEEERKRQER--------WQKEQDRLLQEKYQREQEKLREE---WQRAK----QEAE 934 +W+QEE+ +Q+R W++E+ + +EK ++EK+R++ W + K QE Sbjct: 422 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 481 Query: 935 RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEE 994 RE + E+ + + +E E W + + ++E R E+++ QEE Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQE------ERMWEQDERLREKE-ERMREQKKMWQQEE 534 Query: 995 VVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETS 1054 + E++ + Q++ ++E K ++ + + +K+++ E E + E+ + Q E RE Sbjct: 535 KMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE 594 Query: 1055 VRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTEL--DDYSTNKNGNNKYLDQIGN 1112 ++++ + + E+ + + +K + E+ + + K +Q Sbjct: 595 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654 Query: 1113 MTSSQRRSKKEQVPSGAELERQQILQE 1139 M + + ++++ + E+ + +E Sbjct: 655 MREQEEKMREQEEKMQGQEEKMREQEE 681 Score = 65.5 bits (158), Expect = 3e-10 Identities = 50/179 (27%), Positives = 92/179 (51%), Gaps = 25/179 (13%) Query: 890 VWDQEE---------ERKRQERWQKEQDRLLQEKYQREQEKLRE----EWQRAKQEAERE 936 +W+QEE ER+++ R ++E R +EK Q+++E + E EWQ+ + ++E Sbjct: 381 MWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 440 Query: 937 NSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVV 996 K ++E M + +E + E W + K +E R E++ + +E++ Sbjct: 441 --KLWEQEKM--QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM- 495 Query: 997 HEDQGKKPQDQLVIERERKWEQ--QLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1053 DQ +K DQ ER WEQ +L+E++E+ R Q + +Q+ E+K+ E E++T Sbjct: 496 -RDQEQKMWDQ----EERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549 Score = 65.5 bits (158), Expect = 3e-10 Identities = 70/292 (23%), Positives = 126/292 (43%), Gaps = 40/292 (13%) Query: 890 VWDQEEERKRQER--WQK-----EQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLD 942 +W+QEE+ + QE+ W + EQD L+EK +R +E+ ++ WQ ++E RE K Sbjct: 488 MWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ-KKMWQ--QEEKMREEKK--- 541 Query: 943 EELMVLSSNSMSLTTREPSLATW--EATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ 1000 T+E TW E E + +RE EEE + QEE + E + Sbjct: 542 --------------TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 587 Query: 1001 GK-KPQDQLVIERERKWEQQLQE--EQEQKRLQAEAEEQKRPAEEQK-RQAEIERETSVR 1056 K + Q++ + E+E K ++Q ++ EQE+K + E E++ + EE Q E +E + Sbjct: 588 EKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647 Query: 1057 IYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSS 1116 +++ + + E+ + G K R E + K +Q M Sbjct: 648 MWEQEEKMREQEEKMREQEEK--MQGQEEKMREQEE-----KMQGQEEKMREQEEKMRGQ 700 Query: 1117 QRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLP 1168 + + ++ + E+ +EMR++ D Q ++E S P Sbjct: 701 EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEP 752 Score = 64.3 bits (155), Expect = 8e-10 Identities = 76/339 (22%), Positives = 134/339 (39%), Gaps = 48/339 (14%) Query: 893 QEEERKRQER----W-QKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMV 947 +E+E + QE+ W Q+E+ R +EK R++E+L W++ KQ E+E EE M Sbjct: 306 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL---WEQEKQMREQEQKMRDQEERM- 361 Query: 948 LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGE-------------EERRQPQEE 994 L +E + E W + K + E R E EE+ Q QEE Sbjct: 362 -WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420 Query: 995 VVHEDQGKKPQDQ-LVIERERKWEQQLQEEQEQKRLQAE-----------------AEEQ 1036 + E + K+ Q Q L ++E+ WEQ+ +EQE+K + E +E+ Sbjct: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 480 Query: 1037 KRPAEEQK-RQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDD 1095 R E+Q Q E R+ +++ + D E+ + + + ++ + Sbjct: 481 MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEER--MREQKKMWQQEEKMRE 538 Query: 1096 YSTNKNGNNKYLDQIGNMTSSQR---RSKKEQVPSGAELERQQILQEMRKRTPLHNDNSW 1152 + K DQ M +R R KK + E+++ +QE ++ + W Sbjct: 539 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMW 598 Query: 1153 IRQRSASVNKEPV-SLPGIMRRGESLDNLDSPRSNSWRQ 1190 ++ +E + M E D + W Q Sbjct: 599 EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQ 637 Score = 50.1 bits (118), Expect = 1e-05 Identities = 54/253 (21%), Positives = 99/253 (39%), Gaps = 27/253 (10%) Query: 768 KEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESL- 826 +E EE M + ++ +R K E K D + E+ E + Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 576 Query: 827 --QSSNIESKEINGIHDESNAFESKAS-ESISLKNLKRRSQFFEQGSSDSVVPDLPVPTI 883 Q ++ +E E +E + + K ++ + +EQ D + Sbjct: 577 REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM--------- 627 Query: 884 SAPSRWVWDQEEERKRQER--WQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYL 941 +W+QEE+ + QE W++E+ QE+ REQ EE + ++E RE + + Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ----EEKMQGQEEKMREQEEKM 683 Query: 942 DEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQG 1001 + + + +E E W + K +E G+EE R+ +E + DQ Sbjct: 684 QGQEEKMREQEEKMRGQE------EKMWGQEEKMWGQEEKMWGQEEMREKEERI--RDQK 735 Query: 1002 KKPQDQLVIERER 1014 +K Q++L ER Sbjct: 736 EKMQERLPEHEER 748 Score = 41.6 bits (96), Expect = 0.005 Identities = 26/123 (21%), Positives = 61/123 (49%), Gaps = 2/123 (1%) Query: 380 QNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK-WKDRRKSYTSDLQ-KKKEEREEIEKQAL 437 Q + R E+M++ + Q+ EQ++K +D K W + + D + ++KEER +K+ Sbjct: 471 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMW 530 Query: 438 EKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERV 497 ++ ++ + K Q++++ +Q+ + RM + + E + + Q E++ Sbjct: 531 QQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 590 Query: 498 EEK 500 E+ Sbjct: 591 REQ 593 Score = 35.8 bits (81), Expect = 0.29 Identities = 27/149 (18%), Positives = 67/149 (44%), Gaps = 12/149 (8%) Query: 377 EDVQNLRQLRYEEMQKIKSQ---LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIE 433 E +Q + +E+ +K++ Q ++EQ++K Q K +++ + +K +E+ E++ Sbjct: 639 EKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKMR 698 Query: 434 KQALEKSKRSSKTF--------KEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTM 485 Q + + K + +E ++++E + + + R+ ++ E PP+ Sbjct: 699 GQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEPCLPPSK 758 Query: 486 TVSEASYQSERVEEKGATYPSEIPKEDST 514 + S+ VE G P+++ T Sbjct: 759 VLCNMSHTGS-VEPAGGEAGEGSPQDNPT 786 Score = 35.0 bits (79), Expect = 0.49 Identities = 30/159 (18%), Positives = 78/159 (49%), Gaps = 10/159 (6%) Query: 377 EDVQNLRQLRYE--EMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEK 434 E + LR+ E E +K++ Q +EQ Q+ ++ + + +++ + + +++E E EK Sbjct: 287 EQEKELREQEKELREQKKLREQ-EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEK 345 Query: 435 QALEKSKRSSKTFKEML-QDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQ 493 Q E+ ++ + M QD + ++ + + +M+ ++ ++E +R + E + Sbjct: 346 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEER-----IREREKK 400 Query: 494 SERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQ 532 EE ++ K++ + ++E++ + +LP Q Sbjct: 401 MREEEETMREQEEKMQKQEENMW-EQEEKEWQQQRLPEQ 438 Score = 34.7 bits (78), Expect = 0.64 Identities = 25/151 (16%), Positives = 69/151 (45%), Gaps = 12/151 (7%) Query: 380 QNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEK 439 Q Q + E++ + + ++++Q++ W + W+ + D ++EE+ ++Q + Sbjct: 445 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 504 Query: 440 SKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKR-----PPTMTVSEASYQS 494 + E L+++E + ++ +++M+ ++ + E K+ T E + Sbjct: 505 QEERMWEQDERLREKEERMRE-----QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE 559 Query: 495 ERV--EEKGATYPSEIPKEDSTTFAKREDRV 523 ER+ EK E+ +E ++E+++ Sbjct: 560 ERMREREKKMREEEEMMREQEEKMQEQEEKM 590 Score = 34.3 bits (77), Expect = 0.83 Identities = 32/168 (19%), Positives = 67/168 (39%), Gaps = 5/168 (2%) Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447 EE + + + +EQ++K D K ++ + + +KK E EE+ ++ EK + + Sbjct: 533 EEKMREEKKTQEQEKKTWDQEEKMREEERM--REREKKMREEEEMMREQEEKMQEQEEKM 590 Query: 448 KEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASY--QSERVEEKGATYP 505 +E + Q +K +M+ ++ + E + M E Q E+++E+ Sbjct: 591 REQEEKMWEQEEKMQ-EQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMW 649 Query: 506 SEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 553 + K RE + Q EE+ +R + +M Sbjct: 650 EQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEEKM 697 Score = 33.9 bits (76), Expect = 1.1 Identities = 28/157 (17%), Positives = 73/157 (46%), Gaps = 12/157 (7%) Query: 383 RQLRYEEMQKIKSQ---LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER--------EE 431 +Q+R +E QK++ Q + EQD++ ++ + +++ K + + + ++EER E Sbjct: 345 KQMREQE-QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMRE 403 Query: 432 IEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEAS 491 E+ E+ ++ K + M + E + Q+ +P ++ + ++E + + Sbjct: 404 EEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIR 463 Query: 492 YQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQ 528 Q E ++ + E +E ++E+++ + Q Sbjct: 464 DQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ 500 Score = 33.1 bits (74), Expect = 1.9 Identities = 18/95 (18%), Positives = 53/95 (55%), Gaps = 4/95 (4%) Query: 388 EEMQKIKSQLKEQD---QKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 444 EEM + + +L+EQ+ +K ++ + + ++R + +++++E+ EK+ E+ K Sbjct: 234 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELR 293 Query: 445 KTFKEMLQDRESQNQKSTVPSR-RRMYSFDDVLEE 478 + KE+ + ++ + Q+ + + +M+ ++ + E Sbjct: 294 EQEKELREQKKLREQEEQMQEQEEKMWEQEEKMRE 328 Score = 33.1 bits (74), Expect = 1.9 Identities = 23/173 (13%), Positives = 71/173 (41%) Query: 328 LRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRY 387 +R+++ + R W R +K++ + + E + +R+ Sbjct: 347 MREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEE 406 Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447 ++ + K+++ W+ + +W+ +R + ++E+ +E E++ E+ ++ Sbjct: 407 TMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQE 466 Query: 448 KEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 500 + Q+++ Q+ +M+ ++ + + ++ Q ER+ EK Sbjct: 467 EMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREK 519 Score = 32.7 bits (73), Expect = 2.4 Identities = 19/132 (14%), Positives = 56/132 (42%), Gaps = 1/132 (0%) Query: 330 KKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEE 389 +++ E +++W + +K+ E + ++ + + + E+ Sbjct: 537 REEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEK 596 Query: 390 MQKIKSQLKEQDQK-WQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFK 448 M + + +++EQ++K W+ + W+ + + ++ E+EE ++ EK + + Sbjct: 597 MWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMR 656 Query: 449 EMLQDRESQNQK 460 E + Q +K Sbjct: 657 EQEEKMREQEEK 668 Score = 31.2 bits (69), Expect = 7.0 Identities = 20/132 (15%), Positives = 66/132 (50%), Gaps = 9/132 (6%) Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQ- 435 E + +R+ + E+M + + +L EQ+++ ++ K +D+ + ++ +E+ E + +Q Sbjct: 321 EQEEKMRE-QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQE 379 Query: 436 -------ALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVS 488 +++ +R + K+M ++ E+ ++ ++ ++ +E ++ Sbjct: 380 KMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQK 439 Query: 489 EASYQSERVEEK 500 E ++ E+++E+ Sbjct: 440 EKLWEQEKMQEQ 451 Score = 30.8 bits (68), Expect = 9.2 Identities = 25/116 (21%), Positives = 59/116 (50%), Gaps = 9/116 (7%) Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447 E+M + + +L+EQ+ K ++ K + + K L+++++E E EK+ E+ K + Sbjct: 255 EKMWRQEERLREQEGKMREQEEKMRRQEKR----LREQEKELREQEKELREQKKLREQ-- 308 Query: 448 KEMLQDRES---QNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 500 +E +Q++E + ++ +M+ ++ L E ++ + Q ER+ E+ Sbjct: 309 EEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQ 364 >gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 436 Score = 69.3 bits (168), Expect = 2e-11 Identities = 55/214 (25%), Positives = 104/214 (48%), Gaps = 16/214 (7%) Query: 849 KASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQD 908 K E + + + R Q + G + V + +E+ R+++E+ +++++ Sbjct: 217 KQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEE 276 Query: 909 RLLQEKYQREQEKL---REEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATW 965 ++L++K Q EQE+ +EE R ++E RE + + E+ + + +E + W Sbjct: 277 QMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQM--W 334 Query: 966 EAT---WSEGSKSSDREGTRAGEEERRQPQEEVV--HEDQGKKPQDQLVIERE--RKWEQ 1018 E W + + +E +EE+ Q QEE V E+Q +K ++Q+ + E RK E+ Sbjct: 335 EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEE 394 Query: 1019 QLQEEQ----EQKRLQAEAEEQKRPAEEQKRQAE 1048 Q+ E++ EQK E EEQ +EQ R+ E Sbjct: 395 QMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQE 428 Score = 61.6 bits (148), Expect = 5e-09 Identities = 69/288 (23%), Positives = 129/288 (44%), Gaps = 19/288 (6%) Query: 890 VWDQEEERKRQERWQKEQDRLL--QEKYQREQE-KLRE-EWQRAKQEAE-RENSKYLDEE 944 V +QE + + QE +EQ+ + QE REQE ++RE E Q +QE + RE + E+ Sbjct: 138 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQ 197 Query: 945 LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERR-QPQEEVV--HEDQG 1001 + + +E + E E + ++ + GE+E + Q QEE V E+Q Sbjct: 198 EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQM 257 Query: 1002 KKPQDQLVIERERKWEQQLQ-----EEQEQKRLQAEAEEQKRPAEEQKRQAEIE-RETSV 1055 +K ++Q+ + E+ EQ+ Q E+ EQ+ E EEQ R EEQ R+ E + RE Sbjct: 258 RKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEE 317 Query: 1056 RIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTS 1115 ++ + + + E+ + K + + + + K +Q+ Sbjct: 318 QMREQEEQMGKQEEQMWEQKEQMW----EQKEQMWKQEEQMGEQEEQMQKQEEQV-RKQE 372 Query: 1116 SQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1163 Q R ++EQ+ E R+Q Q ++ + +R++ + ++ Sbjct: 373 EQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQ 420 Score = 52.4 bits (124), Expect = 3e-06 Identities = 68/283 (24%), Positives = 123/283 (43%), Gaps = 23/283 (8%) Query: 890 VWDQEEERKRQERWQKEQDRLL--QEKYQREQE-KLRE-EWQRAKQEAE-RENSKYLDEE 944 V +QE + + QE +EQ+ + QE REQE ++RE E Q +QE + RE + E+ Sbjct: 110 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 169 Query: 945 LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGE-EERRQPQEEVV--HEDQG 1001 + + +E + E E + + GE EE+ Q QEE + E+Q Sbjct: 170 EGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQM 229 Query: 1002 KKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIE-RETSVRIYQY 1060 +K ++Q+ E++ + Q QEEQ QK+ EEQ R EEQ R+ E + RE ++ + Sbjct: 230 RKQEEQM---GEQEEQVQKQEEQVQKQ-----EEQMRKQEEQMREQEEQMREQEEQMLKQ 281 Query: 1061 RRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRS 1120 + + + +E R + E ++ + + ++ Q Sbjct: 282 KEQTEQEEQTGEQEEQM------REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWE 335 Query: 1121 KKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1163 +KEQ+ E +Q Q + + +R++ + K+ Sbjct: 336 QKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ 378 Score = 44.7 bits (104), Expect = 6e-04 Identities = 35/169 (20%), Positives = 76/169 (44%), Gaps = 9/169 (5%) Query: 388 EEMQKIKSQLKEQDQ---KWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 444 E+MQK + Q+ EQ++ K ++ + + +++ + +QK++E+ + E+Q E+ ++ Sbjct: 213 EQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMR 272 Query: 445 KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATY 504 + ++ML+ +E Q+ + EE R + E Q EE+ Sbjct: 273 EQEEQMLKQKEQTEQEEQTGEQEEQMREQ---EEQMREQEEQMREQEEQMREQEEQMGKQ 329 Query: 505 PSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 553 ++ ++ + ++E E Q+ Q EEQ +R + QM Sbjct: 330 EEQMWEQKEQMWEQKEQMWKQEEQMGEQ---EEQMQKQEEQVRKQEEQM 375 Score = 39.3 bits (90), Expect = 0.026 Identities = 35/169 (20%), Positives = 78/169 (46%), Gaps = 16/169 (9%) Query: 388 EEMQKIKSQLKEQD---QKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 444 E+M+K + Q+ EQ+ QK ++ + K +++ + +++++E+ E E+Q L++ +++ Sbjct: 227 EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTE 286 Query: 445 KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATY 504 + +E ++E Q ++ R + EE R + E Q + EE+ Sbjct: 287 Q--EEQTGEQEEQMREQEEQMREQ--------EEQMREQEEQMREQEEQMGKQEEQMWEQ 336 Query: 505 PSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 553 ++ ++ + + E E Q+ Q EEQ +R + QM Sbjct: 337 KEQMWEQKEQMWKQEEQMGEQEEQMQKQ---EEQVRKQEEQMRKQEEQM 382 Score = 38.5 bits (88), Expect = 0.044 Identities = 53/256 (20%), Positives = 106/256 (41%), Gaps = 21/256 (8%) Query: 911 LQEKYQREQEKLREEWQRAKQEAE-RENSKYLDEELMVLSSNSMSLTTREPSLATWEATW 969 L+ K + ++ L +E Q +QE + RE + E+ + + +E + E Sbjct: 37 LKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 96 Query: 970 SEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQDQLVIERERKWEQQLQEEQEQKR 1028 E +EG +E + + QE V E +G+ + Q+ V E+E + +Q + +EQ+ Sbjct: 97 RE------QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 150 Query: 1029 LQAEAEEQKRPAEEQKRQAEIE-RETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKS 1087 E E Q R E Q R+ E + RE ++ + V + +E G G + Sbjct: 151 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV------REQEGQMGEQEGQMGEQ 204 Query: 1088 RSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLH 1147 + + K +Q+G Q R ++EQ+ E ++Q Q ++ + Sbjct: 205 E-----EQMGEQEEQMQKQEEQMGEQ-EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR 258 Query: 1148 NDNSWIRQRSASVNKE 1163 +R++ + ++ Sbjct: 259 KQEEQMREQEEQMREQ 274 Score = 35.8 bits (81), Expect = 0.29 Identities = 40/144 (27%), Positives = 67/144 (46%), Gaps = 15/144 (10%) Query: 928 RAKQEAERENSKYLDEELMVLSSNSMSLTTR----EPSLATWEATWSEGSKSSDREGTRA 983 R E +E + L EEL ++ + + + L T + + + ++EG Sbjct: 3 RITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVR 62 Query: 984 GEEERRQPQEEVVHEDQGK-KPQDQLVIERE---RKWEQQLQEEQEQKRLQA----EAEE 1035 +E + + QE V E +G+ + Q+ V E+E R+ E Q++E++ Q R Q E E Sbjct: 63 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 122 Query: 1036 QKRPAEEQKRQAE---IERETSVR 1056 Q R E Q R+ E E+E VR Sbjct: 123 QVREQEGQVREQEGQVREQEGQVR 146 Score = 35.4 bits (80), Expect = 0.37 Identities = 42/159 (26%), Positives = 74/159 (46%), Gaps = 12/159 (7%) Query: 909 RLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEAT 968 R+ E+ + + +L+EE Q + E + E ++ E L ++ + L Sbjct: 3 RITNEELKEKNAELQEELQLVETE-KSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQV 61 Query: 969 WSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQDQLVIERE---RKWEQQLQEEQ 1024 + + ++EG +E + + QE V E +G+ + Q+ V E+E R+ E Q++E++ Sbjct: 62 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 121 Query: 1025 EQKRLQA----EAEEQKRPAEEQKRQAE---IERETSVR 1056 Q R Q E E Q R E Q R+ E E+E VR Sbjct: 122 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 160 Score = 35.0 bits (79), Expect = 0.49 Identities = 19/96 (19%), Positives = 51/96 (53%), Gaps = 3/96 (3%) Query: 365 ENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQL-KEQDQKWQDDLAKWKDRRKSYTSDLQ 423 E + + E + +R+ + E+M++ + Q+ K+++Q W+ W+ + + + + + Sbjct: 295 EEQMREQEEQMREQEEQMRE-QEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQE-E 352 Query: 424 KKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQ 459 + E+ E+++KQ + K+ + K+ Q R+ + Q Sbjct: 353 QMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQ 388 Score = 34.3 bits (77), Expect = 0.83 Identities = 31/180 (17%), Positives = 80/180 (44%), Gaps = 17/180 (9%) Query: 388 EEMQKIKSQLKEQDQ---KWQDDLAKWKDRRKSYTSDLQKKKEERE------EIEKQALE 438 E++QK + Q+++Q++ K ++ + + +++ + + K+KE+ E E E+Q E Sbjct: 241 EQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMRE 300 Query: 439 KSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTM-----TVSEASYQ 493 + ++ + ++M + E ++ ++ ++ + ++ M + E Q Sbjct: 301 QEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ 360 Query: 494 SERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 553 ++ EE+ ++ K++ + E E Q+ Q +EQ +R + QM Sbjct: 361 MQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQ---KEQMGEQKEQMREQEEQM 417 Score = 34.3 bits (77), Expect = 0.83 Identities = 29/178 (16%), Positives = 82/178 (46%), Gaps = 12/178 (6%) Query: 380 QNLRQLRYEEMQKIKSQLKEQDQKWQDD-LAKWKDRRKSYTSDLQKKKEEREEIEKQALE 438 + +R+ + ++ + LK+++Q Q++ + +++ + +++++E+ E E+Q E Sbjct: 262 EQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMRE 321 Query: 439 KSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVL---EEGKRPPTMTVSEASYQSE 495 + ++ K ++M + +E ++ + +M+ ++ + EE + V + Q Sbjct: 322 QEEQMGKQEEQMWEQKEQMWEQ-----KEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMR 376 Query: 496 RVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 553 + EE+ ++ K++ ++E + Q+ Q EEQ +R + M Sbjct: 377 KQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQ---EEQMGEQKEQMRKQEEHM 431 Score = 32.7 bits (73), Expect = 2.4 Identities = 15/76 (19%), Positives = 44/76 (57%), Gaps = 3/76 (3%) Query: 388 EEMQKIKSQLKEQDQ---KWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 444 E+MQK + Q+++Q++ K ++ + K +++ + + ++KE+ E ++Q E+ ++ Sbjct: 359 EQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMG 418 Query: 445 KTFKEMLQDRESQNQK 460 + ++M + E ++ Sbjct: 419 EQKEQMRKQEEHMGEQ 434 Score = 30.8 bits (68), Expect = 9.2 Identities = 36/174 (20%), Positives = 75/174 (43%), Gaps = 16/174 (9%) Query: 384 QLRYEEMQ--KIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSK 441 Q+R +E Q + + Q++EQ+ + ++ + ++ ++ E+ E+++KQ + + Sbjct: 165 QVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGE 224 Query: 442 RSSKTFK--EMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEE 499 + + K E + ++E Q QK +++ EE R + E Q EE Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQKQ--------EEQMRKQEEQMREQEEQMREQEE 276 Query: 500 KGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 553 + + +E+ T + + R E Q+ Q EEQ +R + QM Sbjct: 277 QMLKQKEQTEQEEQTGEQEEQMREQEE-QMREQ---EEQMREQEEQMREQEEQM 326 Score = 30.8 bits (68), Expect = 9.2 Identities = 16/75 (21%), Positives = 43/75 (57%), Gaps = 3/75 (4%) Query: 384 QLRYEEMQKIKSQLKEQDQ---KWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS 440 Q + E+++K + Q+++Q++ K ++ + K +++ + ++KE+ E E+Q E+ Sbjct: 362 QKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421 Query: 441 KRSSKTFKEMLQDRE 455 ++ K + M + +E Sbjct: 422 EQMRKQEEHMGEQKE 436 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 69.3 bits (168), Expect = 2e-11 Identities = 80/340 (23%), Positives = 142/340 (41%), Gaps = 39/340 (11%) Query: 734 VASVEAGSPAEFSQLQVDDEIIAINN-TKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGK 792 V EA + +Q++ DDE + + K +EA+ + +E + D Sbjct: 74 VPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDA----S 129 Query: 793 AGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNI-ESKEINGIHD-ESNAFESKA 850 P + + T+ +EK + E ++ + +S + N D E N E K Sbjct: 130 LSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKE 189 Query: 851 SESISLKNLKRRS-----------QFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKR 899 E + KR S + + ++VV L IS+ EE K+ Sbjct: 190 KEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISS---------EEPKQ 240 Query: 900 QERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAE-------RENSKYLDEELMVLSSNS 952 +E ++ D + + E++K R E +RA+ EAE ++ K DE + + Sbjct: 241 EEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEK 300 Query: 953 MSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIER 1012 + RE A E K + E R EEE+R +E +++ K+ + ER Sbjct: 301 AAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE----ER 356 Query: 1013 ERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1052 +R E++ + +E++R +AE EE+K EEQKR ++E + Sbjct: 357 QRIKEEEKRAAEERQRARAE-EEEKAKVEEQKRNKQLEEK 395 Score = 54.7 bits (130), Expect = 6e-07 Identities = 147/755 (19%), Positives = 285/755 (37%), Gaps = 99/755 (13%) Query: 406 DDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPS 465 DD + ++ R+ QK++E R E E+ A + R+ +E ++R + ++ + Sbjct: 2 DDFERRRELRR------QKREEMRLEAERIAYQ---RNDDDEEEAARERRRRARQERLRQ 52 Query: 466 RRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTT 525 ++ S V ++ + +V + E K T +++ +D F +R R Sbjct: 53 KQEEESLGQVTDQVEVNAQNSVPDE-------EAKTTTTNTQVEGDDEAAFLERLARR-- 103 Query: 526 EIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGS 585 EE+ L R + + T ASL R+ + T + S Sbjct: 104 ----------EERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKS 153 Query: 586 QTRG-------ISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSS 638 ++R ++ +SY +D W+ D E+ K+ P + Sbjct: 154 ESRQERYEIEETETVTKSYQKND-WR---DAEENKKEDKEKEEEEEEKPKRGSIG----- 204 Query: 639 QKEVAATEEDVTRLPSPTSPFSSLSQDQAATS--KATLSSTSGLDLMS--ESGEGEISPQ 694 + +V E+ T + SL Q ++ K G D +S E E E + Sbjct: 205 ENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKER 264 Query: 695 REVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASV------------EAGSP 742 E R++ + + + K D I+ + E Sbjct: 265 AEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRA 324 Query: 743 AEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWID 802 AE Q ++E A + + K E + +E + R+ +A E ++ Sbjct: 325 AEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVE 384 Query: 803 ATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRR 862 E+ + T IE K +N E A E K ++ LK++ Sbjct: 385 EQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVN----EKKAQEDKLQTAV----LKKQ 436 Query: 863 SQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKL 922 + E+G+ + A + + + K++E + +++ ++K +E+ K Sbjct: 437 GE--EKGTK-----------VQAKREKLQEDKPTFKKEEI---KDEKIKKDKEPKEEVKS 480 Query: 923 REEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTR 982 + ++ E + +N +++ +L + N+ S S+ T EA EG+ + G R Sbjct: 481 FMDRKKGFTEVKSQNGEFMTHKLKH-TENTFSRPGGRASVDTKEA---EGAPQVEA-GKR 535 Query: 983 AGEEERRQPQEEVVHEDQGKKPQDQLVIERE-----RKWEQQLQEEQEQKRLQAEAEEQK 1037 E RR+ + E ++ K+ Q + +E E R+ +++ EE+EQ+R Q EA+ + Sbjct: 536 LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKL 595 Query: 1038 RPAEEQKR-QAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLP-GDRNKSRSTTELDD 1095 R EE++R + EIER + + R+ + + ++ F P G K E + Sbjct: 596 REEEEKRRLKEEIERRRA-EAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLN 654 Query: 1096 YSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAE 1130 S K+ K Q + S+ S+ EQ S E Sbjct: 655 KSVQKSSGVKSTHQAAIV--SKIDSRLEQYTSAIE 687 Score = 48.9 bits (115), Expect = 3e-05 Identities = 68/305 (22%), Positives = 122/305 (40%), Gaps = 52/305 (17%) Query: 892 DQEEERKRQERWQKEQDRLLQEK--YQR----EQEKLREEWQRAKQE--AERENSKYLDE 943 D E R+ R ++E+ RL E+ YQR E+E RE +RA+QE +++ + L + Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61 Query: 944 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003 + N+ + E + T T EG + A EERRQ K+ Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQ-----------KR 110 Query: 1004 PQDQLVIERERKWEQQLQEEQ---EQKRLQAEAEEQKRPAEEQKRQAEIER------ETS 1054 Q+ L ER+++++ + + +R+Q + E + +E+K ++ ER ET Sbjct: 111 LQEAL--ERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETV 168 Query: 1055 VRIYQYRRPVDS-----YDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQ 1109 + YQ D+ D K EE G +++ +++ +T + Sbjct: 169 TKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSL 228 Query: 1110 IGNMTSSQRRSKKEQVPSG-----------------AELERQQILQEMRKRTPLHNDNSW 1152 SS+ ++E+ G AE ER ++ E R+R D Sbjct: 229 KNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKI 288 Query: 1153 IRQRS 1157 +R+ Sbjct: 289 ADERA 293 Score = 47.8 bits (112), Expect = 7e-05 Identities = 57/262 (21%), Positives = 111/262 (42%), Gaps = 22/262 (8%) Query: 895 EERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMS 954 +ER R E +K + + + E+E++REE +RA +E +R + EE + Sbjct: 290 DERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQR-----IKEEEKRAAEERQR 344 Query: 955 LTTREPSLATWEATWSEGSKSSDREGTRAGEEE----------RRQPQEEVVHEDQGKKP 1004 + E A E K + E RA EE R + EE H Q K Sbjct: 345 IKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKI 404 Query: 1005 QDQLVIER-ERKW--EQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYR 1061 + + V ++ E KW E++ QE++ Q + + E+K + KR+ E + + + + + Sbjct: 405 KGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIK 464 Query: 1062 RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSK 1121 D EE S F+ + + ++ ++ T+K K+ + + + Sbjct: 465 DEKIKKDKEPKEEVKS-FMDRKKGFTEVKSQNGEFMTHK---LKHTENTFSRPGGRASVD 520 Query: 1122 KEQVPSGAELERQQILQEMRKR 1143 ++ ++E + L+E+R+R Sbjct: 521 TKEAEGAPQVEAGKRLEELRRR 542 Score = 44.7 bits (104), Expect = 6e-04 Identities = 63/282 (22%), Positives = 128/282 (45%), Gaps = 18/282 (6%) Query: 893 QEEERKRQERWQ-KEQDRLLQEKYQR---EQEKLREEWQRAKQEA-----ERENSKYLDE 943 +EE+R +ER + KE+++ E+ QR E+++ EE QR K+E ER+ ++ +E Sbjct: 319 EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEE 378 Query: 944 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDR-EGTRAGEEERRQPQ-EEVVHEDQG 1001 E + + E A E T +G K + EG E++ ++ + + V + QG Sbjct: 379 EKAKVEEQKRNKQLEEKKHAMQE-TKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQG 437 Query: 1002 KKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYR 1061 ++ ++ +RE+ E + ++E+ + + ++ K P EE K + ++ + Sbjct: 438 EEKGTKVQAKREKLQEDKPTFKKEEIK-DEKIKKDKEPKEEVKSFMD-RKKGFTEVKSQN 495 Query: 1062 RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNN-KYLDQIGNMTSSQRRS 1120 ++ + TE S PG R S T E + + G + L + T S+ Sbjct: 496 GEFMTHKLKHTENTFS--RPGGR-ASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFE 552 Query: 1121 KKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNK 1162 K +Q A LE +++ ++ +R + + R++ + K Sbjct: 553 KLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRK 594 Score = 35.0 bits (79), Expect = 0.49 Identities = 45/203 (22%), Positives = 83/203 (40%), Gaps = 31/203 (15%) Query: 329 RKKKPDKHEDNRRSWASPVYTEADGTF-SRLFQKIYGENGSKSMSDVSAEDVQNLRQLRY 387 R++K + R+ P T+A + SR Q EN + E+ RQ RY Sbjct: 106 RRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENET-----TEKEEKSESRQERY 160 Query: 388 --EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS- 444 EE + + ++ D W+D ++ D K+KEE EE EK KR S Sbjct: 161 EIEETETVTKSYQKND---------WRDAEENKKED--KEKEEEEE------EKPKRGSI 203 Query: 445 --KTFKEMLQDRESQNQKSTVP---SRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEE 499 + M++++ +++Q+ TV ++ S + EE + + +S E +E Sbjct: 204 GENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKE 263 Query: 500 KGATYPSEIPKEDSTTFAKREDR 522 + + + E+ +D+ Sbjct: 264 RAEAERARLEAEERERIKAEQDK 286 Score = 33.5 bits (75), Expect = 1.4 Identities = 27/123 (21%), Positives = 59/123 (47%), Gaps = 12/123 (9%) Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447 EE +K+K + +E + ++ K ++RRK + Q++K+E + + + E+ +R Sbjct: 549 EEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRR----L 604 Query: 448 KEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSE 507 KE ++ R ++ + +R +D L + K+P + S S ++EE+ Sbjct: 605 KEEIERRRAE------AAEKRQKMPEDGLSDDKKPFKCFTPKGS--SLKIEERAEFLNKS 656 Query: 508 IPK 510 + K Sbjct: 657 VQK 659 Score = 33.1 bits (74), Expect = 1.9 Identities = 40/202 (19%), Positives = 84/202 (41%), Gaps = 17/202 (8%) Query: 364 GENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQ 423 GEN + M + + Q + + +I S+ +Q+++ + + K D + Sbjct: 204 GENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKE 263 Query: 424 KKKEEREEIEKQALE--KSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKR 481 + + ER +E + E K+++ K E + + + RR + + EE KR Sbjct: 264 RAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKR 323 Query: 482 PPTMTVSEASYQSERV--EEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQ----SPV 535 A+ + +R+ EEK A + KE+ A+ R+ E + ++ + Sbjct: 324 --------AAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARA 375 Query: 536 EEQSPASLSSLRSRSTQMESTR 557 EE+ A + + R+ Q+E + Sbjct: 376 EEEEKAKVEE-QKRNKQLEEKK 396 Score = 32.7 bits (73), Expect = 2.4 Identities = 39/168 (23%), Positives = 71/168 (42%), Gaps = 30/168 (17%) Query: 380 QNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER------EEIE 433 + LR+ + EEM+ ++ Q ++ A + RR++ L++K+EE +++E Sbjct: 8 RELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVE 67 Query: 434 KQAL-----EKSKRSS----------KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEE 478 A E++K ++ F E L RE + QK + R FD Sbjct: 68 VNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFD----- 122 Query: 479 GKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTE 526 PT+T + S S R++ A + +E S + +R + TE Sbjct: 123 ----PTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETE 166 Score = 32.3 bits (72), Expect = 3.2 Identities = 37/171 (21%), Positives = 73/171 (42%), Gaps = 29/171 (16%) Query: 384 QLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRS 443 +L EE ++IK+ EQD+K D+ A+ + K+ +ERE E + E+ + Sbjct: 271 RLEAEERERIKA---EQDKKIADERARIEAEEKAAA-------QERERREAEERERMREE 320 Query: 444 SKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGAT 503 K E Q R + +K R+R + EE KR A+ + +R++E+ Sbjct: 321 EKRAAEERQ-RIKEEEKRAAEERQR------IKEEEKR--------AAEERQRIKEE--- 362 Query: 504 YPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQME 554 +E A+ E++ E Q ++ E++ + ++ + + Sbjct: 363 -EKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQK 412 Score = 32.3 bits (72), Expect = 3.2 Identities = 49/279 (17%), Positives = 113/279 (40%), Gaps = 24/279 (8%) Query: 379 VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALE 438 ++ LR+ R E + +LK++ Q+ +L +L+KK+EER ++ ++ E Sbjct: 536 LEELRRRRGETESEEFEKLKQKQQEAALEL-----------EELKKKREERRKVLEEE-E 583 Query: 439 KSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVE 498 + ++ + +++ ++ E + K + RR + E+ ++ P +S+ + Sbjct: 584 QRRKQEEADRKLREEEEKRRLKEEIERRRA-----EAAEKRQKMPEDGLSDDKKPFKCFT 638 Query: 499 EKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRV 558 KG++ E E ++ V + Q S ++ + S++ + + Sbjct: 639 PKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPA 698 Query: 559 SASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVED-IKRTPN 617 ++ LP ++ + F S T + P T + + + + +TP+ Sbjct: 699 ASDLPVPAEGVRNIK-SMWEKGNVFSSPT--AAGTPNKETAGLKVGVSSRINEWLTKTPD 755 Query: 618 NVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPT 656 +P+P S L S K ++ V ++ SPT Sbjct: 756 ---GNKSPAPKPSDLRPGDVSSKRNLWEKQSVDKVTSPT 791 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 67.4 bits (163), Expect = 9e-11 Identities = 48/192 (25%), Positives = 96/192 (50%), Gaps = 14/192 (7%) Query: 890 VWDQEEE-RKRQERW--------QKEQDRLLQEKYQREQEKLREEWQRAKQEAE---REN 937 +W QEE+ R+++E W Q+E+ R +EK R++EK+ ++ ++ +++ E R+ Sbjct: 525 MWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQE 584 Query: 938 SKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVH 997 K ++E + E + E + K ++E +EE+ + QEE + Sbjct: 585 EKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR 644 Query: 998 EDQGK-KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQ-KRQAEIERETSV 1055 E + K + Q++ + E+E ++Q ++ EQ+ E EE+ + EE+ +RQ E E V Sbjct: 645 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 704 Query: 1056 RIYQYRRPVDSY 1067 R+ Q + + Sbjct: 705 RLRQQEEKMQEH 716 Score = 66.6 bits (161), Expect = 2e-10 Identities = 67/322 (20%), Positives = 131/322 (40%), Gaps = 47/322 (14%) Query: 890 VWDQEEERKRQER--WQKEQD-RLL------QEKYQREQEKLREEWQRAKQEAERENSKY 940 +W++EE+ +RQE W+KE+ R L QEK + ++EK +EE E RE K Sbjct: 419 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE------EKIREQEKR 472 Query: 941 LDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ 1000 ++E + E E W + K ++E R EEE+RQ QEE+ Sbjct: 473 QEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIR--EEEKRQEQEEMWR--- 527 Query: 1001 GKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQY 1060 Q++ + E+E W Q+ + +++++++ + E+ R E+ Q E RE ++++ Sbjct: 528 ----QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ 583 Query: 1061 RRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNG--NNKYLDQIGNMTSSQR 1118 + + E+ K R E+ K G K +Q M + Sbjct: 584 EEKIREQEEKIREQ---------EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 634 Query: 1119 RSKKEQVPSGAE----LERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRG 1174 + ++++ + E+++ ++E + + W ++ +E + Sbjct: 635 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ-------- 686 Query: 1175 ESLDNLDSPRSNSWRQPPWLNQ 1196 E + + W Q L Q Sbjct: 687 EQEEKMRRQEEKMWEQEVRLRQ 708 Score = 63.2 bits (152), Expect = 2e-09 Identities = 57/247 (23%), Positives = 122/247 (49%), Gaps = 29/247 (11%) Query: 832 ESKEING-IHDESNAFESKASE-SISLKNLKRRSQFFE--------QGSSDSVVPDLPVP 881 E KE N + ++ ES+ SE +++K LKR+ + + Q +D + +L Sbjct: 279 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 338 Query: 882 TISAPSRW----VWDQEEERKRQERW-QKEQDRLLQEKYQREQEKLREEWQRAKQEAE-- 934 + ++ +W++ +++ ++ W Q+E+ + +EK Q ++EK+RE+ ++ +++ E Sbjct: 339 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 398 Query: 935 -RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE 993 R+ ++E + M E E W + K + E + E+E+ + QE Sbjct: 399 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE-EKMHEQEKIREQE 457 Query: 994 EVVHEDQGKKPQDQLVIERERKW--EQQLQEEQEQKRLQAE--------AEEQKRPAEEQ 1043 E E++ + Q++ + + W E++++E++E+ R Q E EQ++ EE+ Sbjct: 458 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEE 517 Query: 1044 KRQAEIE 1050 KRQ + E Sbjct: 518 KRQEQEE 524 Score = 60.5 bits (145), Expect = 1e-08 Identities = 42/170 (24%), Positives = 87/170 (51%), Gaps = 8/170 (4%) Query: 890 VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAE--RENSKYLDEELMV 947 +W QEE+ QE +EQ+ EK R++EK+RE+ ++ +++ E RE + E+ Sbjct: 559 MWRQEEKMHDQEEKIREQE----EKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEK 614 Query: 948 LSSNSMSLTTREPSLATWEATWS-EGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK-PQ 1005 + + +E + E + K ++E +EE+ + QEE++ E + K Q Sbjct: 615 MGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 674 Query: 1006 DQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSV 1055 ++ + E+E K ++Q ++ + Q+ E E + R EE+ ++ + E ++ Sbjct: 675 EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724 Score = 48.5 bits (114), Expect = 4e-05 Identities = 53/267 (19%), Positives = 119/267 (44%), Gaps = 21/267 (7%) Query: 910 LLQEKYQREQEKLREEWQR--AKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEA 967 L Q++ Q E + L +E Q AK +A+ E ++ + + + +E + WE Sbjct: 319 LPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR---LNQQQEEKMWRQEEKIQEWEE 375 Query: 968 TWSEGS-KSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQDQLVIERERK--------WE 1017 E K ++E +EE+ + QEE++ E + K + Q++++ E+E K WE Sbjct: 376 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 435 Query: 1018 QQLQ----EEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTE 1073 ++ + EE+ ++ + +E+KR EE+ R+ E +E ++++ + + E Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 495 Query: 1074 EASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELER 1133 + + ++ + ++ + + ++I R +KE++ E R Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR--QKEKIHEQEEKIR 553 Query: 1134 QQILQEMRKRTPLHNDNSWIRQRSASV 1160 +Q + R+ +H+ IR++ V Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKV 580 Score = 33.5 bits (75), Expect = 1.4 Identities = 34/206 (16%), Positives = 89/206 (43%), Gaps = 16/206 (7%) Query: 329 RKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYE 388 +++K + E+ + W + + + + + E + ++ E + +R R E Sbjct: 359 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR--RQE 416 Query: 389 EM--QKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKT 446 EM +K + ++++ W+ + + K + + +++EE+ + E++ E+ KR + Sbjct: 417 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 476 Query: 447 FKEMLQDRESQNQKSTVPSR--------RRMYSFDDVLEEGKRPPTMTVSEASYQSERVE 498 K Q+ + + Q+ + + +++ + + EE KR E Q E++ Sbjct: 477 AKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKR---QEQEEMWRQEEKIR 533 Query: 499 EKGATY-PSEIPKEDSTTFAKREDRV 523 E+ + E E K+E+++ Sbjct: 534 EQEEIWRQKEKIHEQEEKIRKQEEKM 559 Score = 32.3 bits (72), Expect = 3.2 Identities = 19/91 (20%), Positives = 48/91 (52%), Gaps = 2/91 (2%) Query: 380 QNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEK 439 + + Q + E+M + + ++ EQ++K Q+ K + + + +K +E+ E+I +Q Sbjct: 605 EEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 664 Query: 440 SKRSSKTF--KEMLQDRESQNQKSTVPSRRR 468 ++ K + +E + ++E + Q+ RR+ Sbjct: 665 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 695 Score = 31.2 bits (69), Expect = 7.0 Identities = 26/139 (18%), Positives = 66/139 (47%), Gaps = 6/139 (4%) Query: 388 EEMQKIKSQLKEQDQKWQDDLAK-WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKT 446 EE+ + K ++ EQ++K + K W+ K + + +K +E+ E++ +Q EK + + Sbjct: 536 EEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQE-EKIREQEEKVWRQE-EKIREQEEK 593 Query: 447 FKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERV--EEKGATY 504 +E +++ + ++ T +M ++ + E + + Q E++ +EK Sbjct: 594 IREQ-EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIRE 652 Query: 505 PSEIPKEDSTTFAKREDRV 523 E +E ++E+++ Sbjct: 653 QEEKIREQEEMMQEQEEKM 671 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 67.0 bits (162), Expect = 1e-10 Identities = 52/176 (29%), Positives = 86/176 (48%), Gaps = 18/176 (10%) Query: 892 DQEEERKRQER--WQKEQDRLLQEKYQREQEKLREEWQRAKQEAE-RENSKYLDEELMVL 948 +QEE+ + QE+ W+ QE+ EQEK+REE +R +QE R+ K ++E + Sbjct: 427 EQEEKIREQEKKMWR-------QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479 Query: 949 SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQL 1008 M +E E W + K D+E +EE+ QEE + E Q++ Sbjct: 480 QKEKMH--EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE------QEEK 531 Query: 1009 VIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPV 1064 + E+E K +Q + QEQ+ E EE+ + E+ +RQ E RE +I + + + Sbjct: 532 IREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587 Score = 65.9 bits (159), Expect = 3e-10 Identities = 51/182 (28%), Positives = 95/182 (52%), Gaps = 15/182 (8%) Query: 890 VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQ-EAERENSKYLDEELMVL 948 +W QEE+ QE+ ++E+ R QE+ R++EK+RE+ + +Q E E K +E V Sbjct: 439 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVW 498 Query: 949 SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHE------DQGK 1002 E E W + K ++E +EE+ + QEE++ E +Q + Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEE 558 Query: 1003 KPQDQLVIERERKWEQQLQEEQEQKRLQAE---AEEQKRPAEEQK--RQAEIERETSVRI 1057 K Q+Q E+ R+ E++++E++E+ R Q E +E+K +E+K Q E+ +E ++ Sbjct: 559 KMQEQ---EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKM 615 Query: 1058 YQ 1059 ++ Sbjct: 616 WE 617 Score = 65.9 bits (159), Expect = 3e-10 Identities = 45/184 (24%), Positives = 94/184 (51%), Gaps = 6/184 (3%) Query: 890 VWDQEEERKRQERWQKEQDRLL--QEKYQREQEKLREEWQR--AKQEAERENSKYLDEEL 945 +W Q+E+ QE+ +K+++++ +EK ++EK+RE+ ++ ++E RE + + E+ Sbjct: 477 IWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQE 536 Query: 946 MVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KP 1004 + + +E + E E K +E +EE+ + Q+E + E + K Sbjct: 537 EKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWE 596 Query: 1005 QDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQ-KRQAEIERETSVRIYQYRRP 1063 Q++ + E+E ++Q ++ EQ+ E EE+ + EE+ +RQ E E VR+ Q Sbjct: 597 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 656 Query: 1064 VDSY 1067 + + Sbjct: 657 MQEH 660 Score = 62.4 bits (150), Expect = 3e-09 Identities = 57/247 (23%), Positives = 120/247 (48%), Gaps = 29/247 (11%) Query: 832 ESKEING-IHDESNAFESKASE-SISLKNLKRRSQFFE--------QGSSDSVVPDLPVP 881 E KE N + ++ ES+ SE +++K LKR+ + + Q +D + +L Sbjct: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277 Query: 882 TISAPSRW----VWDQEEERKRQERW-QKEQDRLLQEKYQREQEKLREEWQRAKQEAE-- 934 + ++ +W++ +++ ++ W Q+E+ + +EK Q ++EK+RE+ ++ +++ E Sbjct: 278 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337 Query: 935 -RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE 993 R+ ++E + M E E W + K + E + E+E+ + QE Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE-EKMHEQEKIREQE 396 Query: 994 EVVHEDQGKKPQDQLVIERERKWEQQLQ-EEQEQK---------RLQAEAEEQKRPAEEQ 1043 E E++ + Q++ + + W Q+ + EQE+K R + + EQ++ EE+ Sbjct: 397 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 456 Query: 1044 KRQAEIE 1050 KRQ + E Sbjct: 457 KRQEQEE 463 Score = 62.0 bits (149), Expect = 4e-09 Identities = 42/164 (25%), Positives = 87/164 (53%), Gaps = 6/164 (3%) Query: 890 VWDQEEE-RKRQERWQKEQDRLLQEKYQREQEKL--REEWQRAKQEAERENSKYLDEELM 946 +W QEE+ R+++E W++++ QEK ++++EK+ +EE ++E RE + + + Sbjct: 464 MWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEE 523 Query: 947 VLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQ 1005 + + +E + E E + + + E+E+ + QEE + E + K + Q Sbjct: 524 KIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQ 583 Query: 1006 DQLVIERERK-WEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAE 1048 + + E+E K WEQ+ ++ +EQ+ + E EE+ EE+ + E Sbjct: 584 KEKIREQEEKIWEQE-EKIREQEEMMQEQEEKMWEQEEKMCEQE 626 Score = 59.7 bits (143), Expect = 2e-08 Identities = 41/172 (23%), Positives = 87/172 (50%), Gaps = 6/172 (3%) Query: 890 VWDQEEERKRQERWQKEQDRLL---QEKYQREQEKLREEWQRAKQEAE--RENSKYLDEE 944 VW QEE+ QE +EQ+ + +EK + ++EK+RE+ ++ +++ E +E + + E+ Sbjct: 497 VWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ 556 Query: 945 LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK- 1003 + E E + K ++E +EE+ + QEE++ E + K Sbjct: 557 EEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMW 616 Query: 1004 PQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSV 1055 Q++ + E+E K ++Q ++ + Q+ E E + R EE+ ++ + E ++ Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668 Score = 58.5 bits (140), Expect = 4e-08 Identities = 66/283 (23%), Positives = 126/283 (44%), Gaps = 21/283 (7%) Query: 893 QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNS 952 QE+E K +E Q+E+ R +EK +R++E + W++ ++ +E + EE M Sbjct: 317 QEQEEKIRE--QEEKIREQEEKMRRQEEMM---WEKEEKMRRQEEMMWEKEEKMRRLEEM 371 Query: 953 MSLTTREPSLATWEATWSEGSKSSDREGTRAGEE-----ERRQPQEEVVHEDQGK-KPQD 1006 M +E + E E K ++E R EE E+RQ QE + + K + Q+ Sbjct: 372 M--WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 429 Query: 1007 QLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDS 1066 + + E+E+K +Q ++ EQ++++ EE+++ EE RQ E RE Q + + Sbjct: 430 EKIREQEKKMWRQEEKIHEQEKIR--EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ 487 Query: 1067 YDIPKTEE---ASSGFLPGDRNKSRSTTELDDYSTNK--NGNNKYLDQIGNMTSSQRRSK 1121 I K EE + K R E K K +Q + + + Sbjct: 488 EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQ 547 Query: 1122 KEQVPSGAELERQQILQEMRKR-TPLHNDNSWIRQRSASVNKE 1163 +++ G + E+ Q ++MR++ + IR++ + ++ Sbjct: 548 EQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ 590 Score = 45.1 bits (105), Expect = 5e-04 Identities = 40/171 (23%), Positives = 84/171 (49%), Gaps = 19/171 (11%) Query: 910 LLQEKYQREQEKLREEWQR--AKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEA 967 L Q++ Q E + L +E Q AK +A+ E ++ + + + +E + WE Sbjct: 258 LPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR---LNQQQEEKMWRQEEKIQEWEE 314 Query: 968 TWSEGS-KSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQDQLVIERERK--------WE 1017 E K ++E +EE+ + QEE++ E + K + Q++++ E+E K WE Sbjct: 315 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWE 374 Query: 1018 QQLQ----EEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPV 1064 ++ + EE+ ++ + +E+KR EE+ R+ E +E ++++ + Sbjct: 375 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 425 Score = 35.4 bits (80), Expect = 0.37 Identities = 37/234 (15%), Positives = 102/234 (43%), Gaps = 15/234 (6%) Query: 334 DKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDV----QNLRQLRYEE 389 +K E RR + E + L +K++ + + + E+ Q RQ + + Sbjct: 360 EKEEKMRR--LEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 417 Query: 390 MQKIKSQLKEQDQKWQDDLAK-WKDRRKSYTSDLQKKKEEREEIEKQALEKSK-RSSKTF 447 M + + +++EQ++K ++ K W+ K + + +++E+R+E E+ ++ K R + Sbjct: 418 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477 Query: 448 ---KEMLQDRES--QNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERV--EEK 500 KE + ++E + ++ +M+ ++ + E + + Q E++ +E+ Sbjct: 478 WRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEE 537 Query: 501 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQME 554 E+ +E ++E+++ + ++ Q + + + + + E Sbjct: 538 KIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQE 591 Score = 35.0 bits (79), Expect = 0.49 Identities = 33/205 (16%), Positives = 88/205 (42%), Gaps = 15/205 (7%) Query: 329 RKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYE 388 +++K + E+ + W + + + + + E + ++ E + +R R E Sbjct: 298 QEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR--RQE 355 Query: 389 EM--QKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKT 446 EM +K + + ++ W+ + + K + + +++EE+ + E++ E+ KR + Sbjct: 356 EMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQE 415 Query: 447 FKEMLQDRESQNQKSTVPSR--------RRMYSFDDVLEEGKRPPTMTVSEASYQSERVE 498 K Q+ + + Q+ + + +++ + + EE KR E Q E++ Sbjct: 416 AKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKR---QEQEEMWRQEEKIR 472 Query: 499 EKGATYPSEIPKEDSTTFAKREDRV 523 E+ + + + K+E++V Sbjct: 473 EQEEIWRQKEKMHEQEKIRKQEEKV 497 Score = 33.1 bits (74), Expect = 1.9 Identities = 29/167 (17%), Positives = 74/167 (44%), Gaps = 17/167 (10%) Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER------- 429 E + ++R EE ++ + ++ Q++K ++ W+ + K + + +K+EE+ Sbjct: 444 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEK 503 Query: 430 ----EEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTM 485 EE ++ EK R + +E Q+ + + Q+ + + M + + G++ M Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIRE--QEEKIREQEEKIREQEEMMQ-EQEEKMGEQEEKM 560 Query: 486 TVSEASYQSE---RVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQL 529 E + E R +E+ E +E ++E+++ + ++ Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEM 607 >gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] Length = 1564 Score = 66.6 bits (161), Expect = 2e-10 Identities = 62/290 (21%), Positives = 131/290 (45%), Gaps = 21/290 (7%) Query: 884 SAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDE 943 S+P R +E + + R ++ DR+ + +R +E+ RE + ++E ERE + + Sbjct: 642 SSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDRER 701 Query: 944 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEER-RQPQEEVVHEDQGK 1002 E RE E K DRE R + +R R+ + E E + + Sbjct: 702 E-----------KERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERE 750 Query: 1003 KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA--EEQKRQAEIERETSVRIYQY 1060 + +++ ERER+ E++ + E+E++R + +E++R E++ + + RE I + Sbjct: 751 REREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIRED 810 Query: 1061 RRPVDSYDIPKTE-----EASSGFLPGDRNKSRSTTELDDYST--NKNGNNKYLDQIGNM 1113 R P D +D K++ E S + + + + D Y++ +KN ++ L Q+ Sbjct: 811 RNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRP 870 Query: 1114 TSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1163 S+ S +++ + RK + + ++++ +SV+K+ Sbjct: 871 QESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQ 920 Score = 55.5 bits (132), Expect = 3e-07 Identities = 144/720 (20%), Positives = 263/720 (36%), Gaps = 136/720 (18%) Query: 334 DKHEDNRRSWASPVYTEA---DGTFSRLFQKIYGENGSKSM-------------SDV--S 375 DK D+RR + + DG R +K Y GS S SD S Sbjct: 794 DKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNS 853 Query: 376 AEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQ 435 +D +L + ++ +S+ +D +WK+ + +K ER+E ++ Sbjct: 854 GDDKNEKHRLLSQVVRPQESRSLSPSHLTEDRQGRWKE---------EDRKPERKESSRR 904 Query: 436 ALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSE 495 E+ KE + + Q +++ + RM + D++ + T S+ ++ Sbjct: 905 YEEQE------LKEKVSSVDKQREQTEILESSRMRA-QDIIGHHQSEDRET-SDRAHDEN 956 Query: 496 RVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMES 555 + + K P + KED + T+E SP + Q S+ R +S Sbjct: 957 KKKAKIQKKPIKKKKEDDVGIERGNIETTSE-DGQVFSPKKGQKKKSIEKKRKKSKGDSD 1015 Query: 556 TRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRT 615 + +S +K G +T I++ M + NG +ED ++ Sbjct: 1016 ISDEEAAQQSKKKR--------------GPRTPPITTKEELVEMCNG--KNGILEDSQKK 1059 Query: 616 PNNVVS--TPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTS----PFSSLSQDQAAT 669 + S + PD +++ ++ E AT PSP S P ++ A T Sbjct: 1060 EDTAFSDWSDEDVPDRTEV-----TEAEHTATATTPGSTPSPLSSLLPPPPPVATATATT 1114 Query: 670 SKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTI---- 725 ATL++T+ S S S + IS + TP + + F Sbjct: 1115 VPATLAATTAAAATSFST-----------------SAITISTSATPTNTTNNTFANEDSH 1157 Query: 726 ---------KWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAK 776 K + P + + + P + Q + N + S+ + + Sbjct: 1158 RKCHRTRVEKVETPHVTIEDAQHRKPMD----QKRSSSLGSNRSNRSHTSGRLRSPSNDS 1213 Query: 777 AQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQS--SNIESK 834 A +G +R +GS + EK+ +L +T + + S+ Sbjct: 1214 AHRSGDDQSGRKRVLHSGSRDR------------EKTKSLEITGERKSRIDQLKRGEPSR 1261 Query: 835 EINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQE 894 + +S + S+ S S + + RS GS DS + R+ D+E Sbjct: 1262 STSSDRQDSRSHSSRRSSPESDRQVHSRS-----GSFDSR------DRLQERDRYEHDRE 1310 Query: 895 EERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMS 954 ER+R++ Q+E DR + + R ++ R+ + ++E ER+ + LD E L S+S+ Sbjct: 1311 RERERRDTRQREWDRDADKDWPRNRD--RDRLRERERERERDKRRDLDRERERLISDSVE 1368 Query: 955 LTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERER 1014 T+E++ E K E GE ER D +D L +++ER Sbjct: 1369 RDRDRDRDRTFESSQIESVKRC--EAKLEGEHER----------DLESTSRDSLALDKER 1416 Score = 51.2 bits (121), Expect = 7e-06 Identities = 61/309 (19%), Positives = 123/309 (39%), Gaps = 30/309 (9%) Query: 886 PSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEEL 945 P R DQ + + R + R +E+ QR +R Q E ER+ + +E Sbjct: 609 PERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRH--QGRNDELERDERR--EERR 664 Query: 946 MVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQ 1005 + + RE E + +RE R E +R + +E + ++ ++ + Sbjct: 665 VDRVDDRRDERARERD--------RERERDRERERERERERDREREKERELERERARERE 716 Query: 1006 DQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVD 1065 + ER+R+ ++ ++E++R + E++R E ++R+ E ERE + R Sbjct: 717 REREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERER 776 Query: 1066 SYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQV 1125 + + K E + D+ + + ++ ++N + + +R+SKK Sbjct: 777 ARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGH---------DERKSKKRYR 827 Query: 1126 PSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMR----RGESLDNLD 1181 G+ RQ KR H+ +S N++ L ++R R S +L Sbjct: 828 NEGSPSPRQS-----PKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLT 882 Query: 1182 SPRSNSWRQ 1190 R W++ Sbjct: 883 EDRQGRWKE 891 Score = 50.8 bits (120), Expect = 9e-06 Identities = 81/387 (20%), Positives = 154/387 (39%), Gaps = 42/387 (10%) Query: 893 QEEERKRQERWQKEQDRLLQEKYQREQEKLRE---EWQ---------RAKQEAERENSKY 940 +E ER+R+ ++E++R + + RE++K RE +W+ R K+E RE+ Sbjct: 754 EERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNP 813 Query: 941 LDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ 1000 D S PS E S SD + + E+ + +VV + Sbjct: 814 RDGH-DERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQE 872 Query: 1001 GKK-PQDQLVIERERKW--EQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRI 1057 + L +R+ +W E + E +E R E E +++ + K++ + E S R+ Sbjct: 873 SRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRM 932 Query: 1058 YQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIG-NMTSS 1116 R D ++E+ + D NK ++ + K D +G + Sbjct: 933 ----RAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKE------DDVGIERGNI 982 Query: 1117 QRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGES 1176 + S+ QV S + ++++ +++ RK++ +D S S K P I + E Sbjct: 983 ETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEEL 1042 Query: 1177 LDNLDSPRSNSWRQPPWLNQPTGF--YASSSVQDFSRPPPQLVSTSNRAYMRNP------ 1228 ++ + N + + T F ++ V D + ++ + A P Sbjct: 1043 VEMCNG--KNGILEDSQKKEDTAFSDWSDEDVPDRT----EVTEAEHTATATTPGSTPSP 1096 Query: 1229 -SSSVPPPSAGSVKTSTTGVATTQSPT 1254 SS +PPP + T+TT AT + T Sbjct: 1097 LSSLLPPPPPVATATATTVPATLAATT 1123 Score = 43.1 bits (100), Expect = 0.002 Identities = 71/361 (19%), Positives = 138/361 (38%), Gaps = 35/361 (9%) Query: 331 KKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDV----SAEDVQNLRQLR 386 +KP++ E +RR + + + Q E+ D+ +ED + + Sbjct: 894 RKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRAQDIIGHHQSEDRETSDRAH 953 Query: 387 YEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKT 446 E +K K Q K +K +DD+ + ++ + D Q ++ + +K+++EK ++ SK Sbjct: 954 DENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKGQ-KKKSIEKKRKKSKG 1012 Query: 447 FKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPS 506 ++ + +Q K + G R P +T E E K Sbjct: 1013 DSDISDEEAAQQSKK---------------KRGPRTPPITTKEELV--EMCNGKNGILED 1055 Query: 507 EIPKEDSTTFAKREDR------VTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA 560 KED T F+ D TE + + + +P+ LSSL + +T + Sbjct: 1056 SQKKED-TAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPV-ATATAT 1113 Query: 561 SLPRSYRKTDTVRLTSVVTPR-PFGSQTRGISSLPRSYTMDDAWK--YNGDVEDIKRTPN 617 ++P + T TS T + ++ ++ +D+ + + VE ++ Sbjct: 1114 TVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHV 1173 Query: 618 NVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSST 677 + P + +SSL S + + RL SP++ + S D + K L S Sbjct: 1174 TIEDAQHRKPMDQKRSSSLGSNR--SNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSG 1231 Query: 678 S 678 S Sbjct: 1232 S 1232 Score = 38.5 bits (88), Expect = 0.044 Identities = 38/182 (20%), Positives = 74/182 (40%), Gaps = 27/182 (14%) Query: 973 SKSSDREGTRAGEEERRQPQEE-VVHEDQGK-------KPQDQLVIERERK--------- 1015 S SSDR+ +R+ R P+ + VH G + +D+ +RER+ Sbjct: 1262 STSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQR 1321 Query: 1016 -WEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEE 1074 W++ ++ + R + E++R E KR+ +++RE I D +T E Sbjct: 1322 EWDRDADKDWPRNRDRDRLRERERERERDKRR-DLDRERERLISDSVERDRDRDRDRTFE 1380 Query: 1075 AS--------SGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVP 1126 +S L G+ + +T D + +K +K L + + + + E + Sbjct: 1381 SSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLE 1440 Query: 1127 SG 1128 +G Sbjct: 1441 AG 1442 Score = 36.6 bits (83), Expect = 0.17 Identities = 39/204 (19%), Positives = 80/204 (39%), Gaps = 17/204 (8%) Query: 318 SRQPSY-VPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSA 376 S PS+ + +P RK+ P +H R + + R ++ G + S Sbjct: 372 SPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTRGKRDREKDSR 431 Query: 377 EDVQNLRQLRYEEMQKIKSQLKE----QDQKWQDDLAKWKDRRKSYTS-DLQKKKEEREE 431 E+ + YE+ Q ++ +D + + D +DRR+ S D++ +E R+ Sbjct: 432 EERE------YEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSREMRDY 485 Query: 432 IEKQALEKSKRSSKTFKEM-----LQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMT 486 + R S++ ++ + R++ ++ T P R Y + + EE R Sbjct: 486 SRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRTEIRN 545 Query: 487 VSEASYQSERVEEKGATYPSEIPK 510 S +SE ++ +P+ Sbjct: 546 ESRNESRSEIRNDRMGRSRGRVPE 569 Score = 30.8 bits (68), Expect = 9.2 Identities = 50/255 (19%), Positives = 90/255 (35%), Gaps = 42/255 (16%) Query: 414 RRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFD 473 R K Y+S+ ++ E ++ ++ ++ T + ES + SR R + Sbjct: 66 RGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKE 125 Query: 474 DVLEEGKRPPTMTVSEASYQSER-----------------VEEKGATYPSEIPKEDSTTF 516 D+ +R P +++ R +E K E+ K + Sbjct: 126 DIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENM 185 Query: 517 AKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTS 576 KRE+ + + ++ + + SP+ S+S + +S+ S+S + RKT V Sbjct: 186 EKREE-IIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAV---- 240 Query: 577 VVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSL 636 P Q R K N + RTP S P P P+ L Sbjct: 241 ---SSPLLDQQRNS-------------KTNQSKKKGPRTP----SPPPPIPEDIALGKKY 280 Query: 637 SSQKEVAATEEDVTR 651 + +V E+ TR Sbjct: 281 KEKYKVKDRIEEKTR 295 Score = 30.8 bits (68), Expect = 9.2 Identities = 49/260 (18%), Positives = 102/260 (39%), Gaps = 12/260 (4%) Query: 386 RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKK--KEEREEIEKQALEKSKRS 443 R +E + + + +E+D++ + + + +DR + +L+++ +E E EK+ + R Sbjct: 671 RRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRD 730 Query: 444 SKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGAT 503 +E ++RE +K R + E +R A + + E + Sbjct: 731 RDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDW 790 Query: 504 YPSEIPKEDSTTFAK--REDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSAS 561 + ++D + REDR + +S ++ S S +S + E + S + Sbjct: 791 EDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDA 850 Query: 562 LPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVS 621 K + RL S V RP ++R +S + WK E+ ++ S Sbjct: 851 YNSGDDKNEKHRLLSQVV-RP--QESRSLSPSHLTEDRQGRWK-----EEDRKPERKESS 902 Query: 622 TPAPSPDASQLASSLSSQKE 641 + + SS+ Q+E Sbjct: 903 RRYEEQELKEKVSSVDKQRE 922 >gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] Length = 523 Score = 65.9 bits (159), Expect = 3e-10 Identities = 69/272 (25%), Positives = 131/272 (48%), Gaps = 29/272 (10%) Query: 802 DATSGIYNSEKSSN------------LSVTTDFSESLQSSNIESKEINGIHDESNAFESK 849 D+ +GIY ++S+ L+V D S ++ S E+ IN + S E K Sbjct: 68 DSATGIYGEGRASSTTLEDLESQYQELAVALDSSSAIISQLTEN--INSLVRTSK--EEK 123 Query: 850 ASESISLKNLKRRSQFFEQGSSDSVVPDLP-----VPTISAPSRWVWDQEEERKRQERWQ 904 E ++ L R + +++ + P+ P V + + + + E RQ + + Sbjct: 124 KHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAE 183 Query: 905 KEQDRLLQEKYQREQEKLREEWQRAKQEAER--ENSKYLDEELMVLSSNSMSLTTREPSL 962 E +++L +R++E+LRE+ +R +++ ER E + L E+ L L +E L Sbjct: 184 VENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERL 243 Query: 963 ATWEATWSEGSKS-SDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQ 1021 E E + ++E +EER + QEE +HE + + + + ER R+ E++L Sbjct: 244 CEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQE---ERLREQEERLC 300 Query: 1022 EEQEQKRLQAE--AEEQKRPAEEQKRQAEIER 1051 E++E+ R Q E E+++R E+++R E E+ Sbjct: 301 EQEERLREQEERLCEQEERLREQEERLCEQEK 332 Score = 57.8 bits (138), Expect = 7e-08 Identities = 77/316 (24%), Positives = 132/316 (41%), Gaps = 29/316 (9%) Query: 824 ESLQS-SNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPT 882 E LQ +N KE+ + + A E + ++ +SL N ++ + EQ Sbjct: 160 EQLQDETNHLRKELESVGRQLQA-EVENNQMLSLLNRRQEERLREQEER----------- 207 Query: 883 ISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQR---EQEKLREEWQRAKQEAER--EN 937 + + +QEE QE +EQ+ L+E+ +R ++E+LRE +R ++ ER E Sbjct: 208 LREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQ 267 Query: 938 SKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVH 997 + L E+ L L +E L E E + + R E+E R ++E Sbjct: 268 EERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERL 327 Query: 998 EDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRI 1057 +Q K P + ++E K +Q + ++EQ+RL E E EE Q + R+ R+ Sbjct: 328 CEQEKLPGQERLLEEVEKLLEQERRQEEQERL-LERERLLEEVEELLEQERL-RQQDERL 385 Query: 1058 YQYRRPVDSYDIPKTE---EASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMT 1114 +Q + + + E E L R + RS E N NK Q+ Sbjct: 386 WQQETLQELERLRELERMLELGWEALYEQRAEPRSGFE------ELNNENKSTLQLEQQV 439 Query: 1115 SSQRRSKKEQVPSGAE 1130 ++S + P G+E Sbjct: 440 KELKKSGGAEEPRGSE 455 Score = 31.6 bits (70), Expect = 5.4 Identities = 33/188 (17%), Positives = 83/188 (44%), Gaps = 11/188 (5%) Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEI-EKQALEKSKRSSKT 446 E + + + +L+EQ+++ + + +++ + ++ +E+ E + E++ L +R + Sbjct: 283 ERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEE 342 Query: 447 FKEML-QDRESQNQKSTVPSRRRMYSFDDVLEEGK---------RPPTMTVSEASYQSER 496 +++L Q+R + Q+ + R + +++LE+ + + T+ E + ER Sbjct: 343 VEKLLEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELER 402 Query: 497 VEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMEST 556 + E G E E + F + + + +QL Q ++S + S S Sbjct: 403 MLELGWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEPRGSESAAAARP 462 Query: 557 RVSASLPR 564 A +P+ Sbjct: 463 VAGAPVPQ 470 >gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] Length = 2817 Score = 65.9 bits (159), Expect = 3e-10 Identities = 64/262 (24%), Positives = 120/262 (45%), Gaps = 30/262 (11%) Query: 809 NSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQ 868 NS K +N + D +N KE + + + ++ + A S++ + F ++ Sbjct: 343 NSPKENN---SEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQE 399 Query: 869 GSSDSVVPDLP--------------VPTISAP---SRWVWDQEEERKRQERWQKEQDRLL 911 + S +P P VP P + V D++E K++ R Q E + Sbjct: 400 RGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAV 459 Query: 912 QE-KYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWS 970 + + +RE+E+ R E QR AE+ K LDE+L +L RE Sbjct: 460 ERARKRREEEERRMEEQRKAACAEK--LKRLDEKLGILEKQPSPEEIREREREKEREREK 517 Query: 971 EGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQ 1030 E K ++E + E++R + QE+ ++ K+ + Q +E+ERK QE++++ Q Sbjct: 518 ELEKEQEQEREKEREKDRERQQEK--EKELEKEQEKQREMEKERK-----QEKEKELERQ 570 Query: 1031 AEAEEQKRPAEEQKRQAEIERE 1052 E E++ + +EQ+++ E+E+E Sbjct: 571 KEKEKELQKMKEQEKECELEKE 592 Score = 45.1 bits (105), Expect = 5e-04 Identities = 52/231 (22%), Positives = 96/231 (41%), Gaps = 20/231 (8%) Query: 317 KSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSA 376 + RQ S + A + + + + E+ RR A+ RL +K+ S ++ Sbjct: 448 RRRQQSEISAAVERARKRREEEERRMEEQRKAACAE-KLKRLDEKLGILEKQPSPEEIRE 506 Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIE--- 433 + R +E ++ K KEQ+Q+ + + K ++R++ +L+K++E++ E+E Sbjct: 507 RE-------REKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKER 559 Query: 434 KQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQ 493 KQ EK K ++ LQ + Q ++ + R E P + E+ Sbjct: 560 KQEKEKELERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENS 619 Query: 494 SERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLS 544 + EE T ++DS K V E + S S + PA LS Sbjct: 620 CNKEEEPVFT------RQDSNRSEKEATPVVHETEPESGS---QPRPAVLS 661 Score = 38.9 bits (89), Expect = 0.034 Identities = 38/157 (24%), Positives = 79/157 (50%), Gaps = 31/157 (19%) Query: 892 DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 951 ++++E++++ QKE+++ LQ K++E+ + + E ERE L+E+ Sbjct: 558 ERKQEKEKELERQKEKEKELQ--------KMKEQEKECELEKEREK---LEEK------- 599 Query: 952 SMSLTTREPSLATW-EATWSEGSKSSDREGTRAGEEERRQPQE--EVVHE---DQGKKPQ 1005 + REP+L E SE S + + E ++ R +E VVHE + G +P+ Sbjct: 600 ---IEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPR 656 Query: 1006 DQLVIERERKWEQQL----QEEQEQKRLQAEAEEQKR 1038 ++ +++++ L Q +QEQ + Q ++Q++ Sbjct: 657 PAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQ 693 Score = 32.3 bits (72), Expect = 3.2 Identities = 32/150 (21%), Positives = 62/150 (41%), Gaps = 13/150 (8%) Query: 394 KSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS-----KTFK 448 K Q+ ++D+ W K + R++S S ++ +R E E++ +E+ ++++ K Sbjct: 435 KQQVADEDEIW-----KQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLD 489 Query: 449 EMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEI 508 E L E Q + R R + E K E ER +EK E Sbjct: 490 EKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQ 549 Query: 509 PKEDSTTFAKREDRVTTEIQLPSQSPVEEQ 538 K+ +++++ E +L Q E++ Sbjct: 550 EKQREMEKERKQEK---EKELERQKEKEKE 576 >gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo sapiens] Length = 624 Score = 65.5 bits (158), Expect = 3e-10 Identities = 83/377 (22%), Positives = 156/377 (41%), Gaps = 38/377 (10%) Query: 814 SNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDS 873 SN ++ + Q++ E +E+ E+ +F S A E S K+ +R+ G S S Sbjct: 256 SNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKG-----GRSRS 310 Query: 874 VVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEA 933 + SR RKR + K + R R++++ R + K+ Sbjct: 311 HT--------RSKSRSSSKSHSRRKRSQ--SKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 360 Query: 934 ERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE 993 RE K S TRE + E K DRE R E+ER + +E Sbjct: 361 SRERRKSRSRS----HSRDKRKDTRE------KIKEKERVKEKDREKEREREKEREKEKE 410 Query: 994 EVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1053 ++D+ K+ + ++E+ E++ ++E E+ R + + +EQ + E +K +++ E Sbjct: 411 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 470 Query: 1054 SVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNM 1113 + + R P SY+ + +SS R++S S + + + + + N Sbjct: 471 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 530 Query: 1114 TSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV-----NKEPVSLP 1168 +R +++ + E ER MRK + + + + S S+ NKEP S Sbjct: 531 KDKKREKERDHISERRERERS---TSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS-- 585 Query: 1169 GIMRRGESLDNLDSPRS 1185 + +D+ D+PR+ Sbjct: 586 ---SVSKEVDDKDAPRT 599 Score = 57.4 bits (137), Expect = 9e-08 Identities = 37/191 (19%), Positives = 92/191 (48%), Gaps = 15/191 (7%) Query: 892 DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 951 D+E E+ R++ +K+++R +++++++++K +E+ Q ++E E++ SK +DE+ Sbjct: 418 DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK------R 471 Query: 952 SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIE 1011 +R P ++ A+ S S +R R+ R + + + P + + Sbjct: 472 KKDKKSRTPP-RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 530 Query: 1012 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP-------- 1063 +++K E++ E++ + +K + ++ + TS++ ++ + Sbjct: 531 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 590 Query: 1064 VDSYDIPKTEE 1074 VD D P+TEE Sbjct: 591 VDDKDAPRTEE 601 Score = 48.1 bits (113), Expect = 6e-05 Identities = 51/243 (20%), Positives = 99/243 (40%), Gaps = 11/243 (4%) Query: 350 EADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLA 409 EA S + G++ + + R ++ +SQ K + + + Sbjct: 284 EAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRS 343 Query: 410 KWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRM 469 + KDRR+S S +K+ + RE + ++ S+ K +E ++++E +K R R Sbjct: 344 RQKDRRRS-KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERERE 402 Query: 470 YSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRV------ 523 + E GK E + ++ +++ E K+ K +D+ Sbjct: 403 KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 462 Query: 524 -TTEIQLPSQSPVEEQSP--ASLSSLRSRSTQME-STRVSASLPRSYRKTDTVRLTSVVT 579 + EI + + ++P + +S RSRS+ E R S S RS R + T++ S + Sbjct: 463 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 522 Query: 580 PRP 582 P P Sbjct: 523 PSP 525 Score = 48.1 bits (113), Expect = 6e-05 Identities = 48/231 (20%), Positives = 90/231 (38%), Gaps = 14/231 (6%) Query: 386 RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSK 445 R +E + K + +E++++ + + K KDR K D +K KE+ E E++ + R + Sbjct: 389 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE 448 Query: 446 TFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKR----PPTMTVSEASYQSERVEEKG 501 KE QD+E + +K R D+ ++ K+ P + S S S R + Sbjct: 449 --KEKEQDKEKEREKD------RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 500 Query: 502 ATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSL--RSRSTQMESTRVS 559 + S S T ++ R + + E+ +S R RST M + Sbjct: 501 RSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSND 560 Query: 560 ASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVE 610 K T P S ++ + T ++ ++NG+ + Sbjct: 561 RDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQ 611 >gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo sapiens] Length = 508 Score = 65.5 bits (158), Expect = 3e-10 Identities = 83/377 (22%), Positives = 156/377 (41%), Gaps = 38/377 (10%) Query: 814 SNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDS 873 SN ++ + Q++ E +E+ E+ +F S A E S K+ +R+ G S S Sbjct: 140 SNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKG-----GRSRS 194 Query: 874 VVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEA 933 + SR RKR + K + R R++++ R + K+ Sbjct: 195 HT--------RSKSRSSSKSHSRRKRSQ--SKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 244 Query: 934 ERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE 993 RE K S TRE + E K DRE R E+ER + +E Sbjct: 245 SRERRKSRSRS----HSRDKRKDTRE------KIKEKERVKEKDREKEREREKEREKEKE 294 Query: 994 EVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1053 ++D+ K+ + ++E+ E++ ++E E+ R + + +EQ + E +K +++ E Sbjct: 295 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 354 Query: 1054 SVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNM 1113 + + R P SY+ + +SS R++S S + + + + + N Sbjct: 355 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 414 Query: 1114 TSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV-----NKEPVSLP 1168 +R +++ + E ER MRK + + + + S S+ NKEP S Sbjct: 415 KDKKREKERDHISERRERERS---TSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS-- 469 Query: 1169 GIMRRGESLDNLDSPRS 1185 + +D+ D+PR+ Sbjct: 470 ---SVSKEVDDKDAPRT 483 Score = 57.4 bits (137), Expect = 9e-08 Identities = 37/191 (19%), Positives = 92/191 (48%), Gaps = 15/191 (7%) Query: 892 DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 951 D+E E+ R++ +K+++R +++++++++K +E+ Q ++E E++ SK +DE+ Sbjct: 302 DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK------R 355 Query: 952 SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIE 1011 +R P ++ A+ S S +R R+ R + + + P + + Sbjct: 356 KKDKKSRTPP-RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 414 Query: 1012 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP-------- 1063 +++K E++ E++ + +K + ++ + TS++ ++ + Sbjct: 415 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 474 Query: 1064 VDSYDIPKTEE 1074 VD D P+TEE Sbjct: 475 VDDKDAPRTEE 485 Score = 48.1 bits (113), Expect = 6e-05 Identities = 51/243 (20%), Positives = 99/243 (40%), Gaps = 11/243 (4%) Query: 350 EADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLA 409 EA S + G++ + + R ++ +SQ K + + + Sbjct: 168 EAQSFISAAIEPESGKSNERKGGRSRSHTRSKSRSSSKSHSRRKRSQSKHRSRSHNRSRS 227 Query: 410 KWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRM 469 + KDRR+S S +K+ + RE + ++ S+ K +E ++++E +K R R Sbjct: 228 RQKDRRRS-KSPHKKRSKSRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKERERE 286 Query: 470 YSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRV------ 523 + E GK E + ++ +++ E K+ K +D+ Sbjct: 287 KEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKD 346 Query: 524 -TTEIQLPSQSPVEEQSP--ASLSSLRSRSTQME-STRVSASLPRSYRKTDTVRLTSVVT 579 + EI + + ++P + +S RSRS+ E R S S RS R + T++ S + Sbjct: 347 RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRS 406 Query: 580 PRP 582 P P Sbjct: 407 PSP 409 Score = 48.1 bits (113), Expect = 6e-05 Identities = 48/231 (20%), Positives = 90/231 (38%), Gaps = 14/231 (6%) Query: 386 RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSK 445 R +E + K + +E++++ + + K KDR K D +K KE+ E E++ + R + Sbjct: 273 RVKEKDREKEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE 332 Query: 446 TFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKR----PPTMTVSEASYQSERVEEKG 501 KE QD+E + +K R D+ ++ K+ P + S S S R + Sbjct: 333 --KEKEQDKEKEREKD------RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRR 384 Query: 502 ATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSL--RSRSTQMESTRVS 559 + S S T ++ R + + E+ +S R RST M + Sbjct: 385 RSRSSSRSPRTSKTIKRKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSND 444 Query: 560 ASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVE 610 K T P S ++ + T ++ ++NG+ + Sbjct: 445 RDGKEKLEKNSTSLKEKEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQ 495 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 65.1 bits (157), Expect = 4e-10 Identities = 75/365 (20%), Positives = 161/365 (44%), Gaps = 40/365 (10%) Query: 817 SVTTDFSESL-QSSNIESKEING-----IHDESNAFESKASESISLKNLKRRSQFFEQGS 870 +VT D E+L + + + I G I + S+ + + ES S K++ + + Sbjct: 187 TVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFR 246 Query: 871 SDSVVPDLPVPTISAPSRWVWDQEEERK-----------------RQERWQKEQDRLLQE 913 V P +P P I+ + EE+++ +E+ +KE++R E Sbjct: 247 RFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIE 306 Query: 914 KYQREQEKLRE-EWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEG 972 K +RE+E+ RE E +R ++E ERE + ++E R+ + E Sbjct: 307 KERRERERERERERERREREREREREREREKEKERERERERD-RDRDRTKERDRDRDRER 365 Query: 973 SKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAE 1032 + DRE + ++R + +E+ ++ ++ + + ERER+ E++ + E+E++R + Sbjct: 366 DRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERER 425 Query: 1033 AEEQKRPAEEQKRQA----EIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSR 1088 +++KR EE + A ++ER+ + Y+ + +++I + ++ +R + R Sbjct: 426 EKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEER 485 Query: 1089 STTE----------LDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQ 1138 L+DY +++ Y R + E + E+++ L+ Sbjct: 486 RREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEE-LE 544 Query: 1139 EMRKR 1143 E+R+R Sbjct: 545 EIRQR 549 Score = 48.5 bits (114), Expect = 4e-05 Identities = 39/187 (20%), Positives = 78/187 (41%), Gaps = 24/187 (12%) Query: 389 EMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKR------ 442 E +K++ +L+E++ +Q+ L W+ R + T + +K+ E EE ++ +++KR Sbjct: 442 ERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLE 501 Query: 443 ------------SSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDV----LEEGKRPPTMT 486 ++ L+DRE + + +R +++ L EG P Sbjct: 502 DYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAE 561 Query: 487 VSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDR--VTTEIQLPSQSPVEEQSPASLS 544 + ++ER + E +E+ K E R E + P Q P + + +S Sbjct: 562 LQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPIS 621 Query: 545 SLRSRST 551 S S S+ Sbjct: 622 SAPSVSS 628 Score = 45.8 bits (107), Expect = 3e-04 Identities = 45/205 (21%), Positives = 91/205 (44%), Gaps = 20/205 (9%) Query: 892 DQEE--ERKRQERWQKEQDRLLQEKYQ----REQEKLREEWQRAKQEAERENSKYLDEEL 945 D+E+ ER++ ER +E++ QE+ + RE++K RE + A++E ER + + Sbjct: 436 DEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKR 495 Query: 946 MVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK--- 1002 + +P A + DRE +E R+ ++E + E + + Sbjct: 496 LKEFLEDYDDDRDDPKYYRGSALQK---RLRDREKEMEADERDRKREKEELEEIRQRLLA 552 Query: 1003 --KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVR---- 1056 P ++R + ++ ++ Q ++ ++E EE+++ +E+KR+ +E E Sbjct: 553 EGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPC 612 Query: 1057 IYQYRRPVDSYDIPKTEEASSGFLP 1081 + RP+ S P AS P Sbjct: 613 LKPTLRPISS--APSVSSASGNATP 635 Score = 45.1 bits (105), Expect = 5e-04 Identities = 77/351 (21%), Positives = 127/351 (36%), Gaps = 44/351 (12%) Query: 386 RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSK 445 R +E + + + +++D+ + + KDR +S +++E E E++ + +R + Sbjct: 353 RTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERE 412 Query: 446 TFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSE------RVEE 499 +E ++RE + +K R R +D E K + EA+YQ R + Sbjct: 413 REREREREREREREKDK--KRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERK 470 Query: 500 KGATYPSEIPKEDS-----TTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQME 554 K Y E +E+ AKR + P + A LR R +ME Sbjct: 471 KTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEME 530 Query: 555 STRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKR 614 + + + RL + P P DA + E +R Sbjct: 531 ADERDRKREKEELEEIRQRLLAEGHPDP------------------DAELQRMEQEAERR 572 Query: 615 TPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLP--SPT-SPFSSLSQDQAATSK 671 + P + + ++E EE+ + P PT P SS +A+ Sbjct: 573 RQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGN 632 Query: 672 ATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFG 722 AT +T G ES G I P E S Q Q + R I G SL G Sbjct: 633 AT-PNTPG----DESPCGIIIP-HENSPDQQQPEEHRPKI----GLSLKLG 673 Score = 37.4 bits (85), Expect = 0.098 Identities = 15/62 (24%), Positives = 35/62 (56%) Query: 407 DLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSR 466 +++K++D K + KK++ER+EIEK+ E+ + + + ++RE + ++ + Sbjct: 280 EISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEK 339 Query: 467 RR 468 R Sbjct: 340 ER 341 Score = 36.2 bits (82), Expect = 0.22 Identities = 43/219 (19%), Positives = 81/219 (36%), Gaps = 26/219 (11%) Query: 329 RKKKPDKHEDNRRSWAS------PVYTEAD------------------GTFSRLFQKIYG 364 RKKK +K ED R + P+ T+ D F +K+ Sbjct: 234 RKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEE 293 Query: 365 ENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQK 424 E G K E + R+ E ++ + + +E++++ + + K ++R + D + Sbjct: 294 EKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDRDR 353 Query: 425 KKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPT 484 KE + +++ R + + +DR +KS R R + E + Sbjct: 354 TKERDRDRDRE--RDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERER 411 Query: 485 MTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRV 523 E + ER EK E +ED+ K E ++ Sbjct: 412 EREREREREREREREKDKKRDREEDEEDAYERRKLERKL 450 Score = 31.6 bits (70), Expect = 5.4 Identities = 42/189 (22%), Positives = 72/189 (38%), Gaps = 28/189 (14%) Query: 822 FSESLQSSNI-ESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPV 880 + E L++ I E K+ E+ E + E K KR +F E D D Sbjct: 457 YQERLKNWEIRERKKTREYEKEAEREEERRREMA--KEAKRLKEFLEDYDDDR--DDPKY 512 Query: 881 PTISAPSRWVWDQEEERKRQERWQK-----------------------EQDRLLQEKYQR 917 SA + + D+E+E + ER +K E R+ QE +R Sbjct: 513 YRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERR 572 Query: 918 EQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSD 977 Q ++++E + ++E E++ + EE M +P+L + S S S + Sbjct: 573 RQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGN 632 Query: 978 REGTRAGEE 986 G+E Sbjct: 633 ATPNTPGDE 641 Score = 30.8 bits (68), Expect = 9.2 Identities = 30/176 (17%), Positives = 66/176 (37%), Gaps = 3/176 (1%) Query: 395 SQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDR 454 S+ ++ +K +++ K + R+ + ++++ ERE ++ + +R + +E ++R Sbjct: 282 SKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKER 341 Query: 455 ESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDST 514 E + ++ R + D E + S+ + R EK E +E Sbjct: 342 ERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERE- 400 Query: 515 TFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTD 570 +RE E + + E + R R E L R R+ + Sbjct: 401 --REREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKE 454 >gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] Length = 238 Score = 64.3 bits (155), Expect = 8e-10 Identities = 48/181 (26%), Positives = 94/181 (51%), Gaps = 21/181 (11%) Query: 893 QEEERKRQ-ERWQKEQDRLL---QEKYQREQEKLREE----WQRAKQEAERENSKYLDEE 944 +EEER R+ E+ +E++ ++ +EK Q ++EK+RE+ W++ ++ E+E + EE Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61 Query: 945 LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEE---------ERRQPQEEV 995 M M R P E W + + ++E ++ E+++ QEE Sbjct: 62 KMWEQEEKMWEQQRLPEQK--EKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119 Query: 996 VHEDQGK-KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETS 1054 + E + K + Q++++ E+E K ++Q ++ EQ+ E EE+ R +E+K Q + E+ Sbjct: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR-EQEEKMQGQEEKMRD 178 Query: 1055 V 1055 V Sbjct: 179 V 179 Score = 63.2 bits (152), Expect = 2e-09 Identities = 49/161 (30%), Positives = 82/161 (50%), Gaps = 24/161 (14%) Query: 890 VWDQEEERKRQER--WQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMV 947 +W+QEE+ + QE W++E+ QE+ EQ++L E+ ++ ++ ER K EE M Sbjct: 42 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREK---EERM- 97 Query: 948 LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQ 1007 RE + W+ K +E +EE+ Q QEE++ E Q +K Q+Q Sbjct: 98 ----------REQKM--WQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWE-QEEKMQEQ 144 Query: 1008 LVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAE 1048 E+ WEQ+ ++ +EQ+ E EE+ + EE+ R E Sbjct: 145 ----EEKMWEQE-EKMREQEEKMREQEEKMQGQEEKMRDVE 180 Score = 40.8 bits (94), Expect = 0.009 Identities = 30/123 (24%), Positives = 64/123 (52%), Gaps = 14/123 (11%) Query: 388 EEMQKIKSQLKEQDQK-WQDDLAKWKDRR------KSYTSDLQ-KKKEEREEIEK--QAL 437 E+MQ+ + ++ EQ++K W+ + W+ +R K + D + ++KEER +K Q + Sbjct: 47 EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQV 106 Query: 438 EKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERV 497 EK + KT +E +Q++E + Q+ M+ ++ ++E + + Q E++ Sbjct: 107 EKMREKKKTQEEKMQEQEEKMQE----QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKM 162 Query: 498 EEK 500 E+ Sbjct: 163 REQ 165 Score = 32.3 bits (72), Expect = 3.2 Identities = 26/157 (16%), Positives = 74/157 (47%), Gaps = 8/157 (5%) Query: 377 EDVQNLRQLRYEEMQKIKSQLKEQDQ-KWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQ 435 E+ + +R+ + E+MQ+ + +++EQ++ W+ + + K + + + ++E + E+Q Sbjct: 16 EEEEMMRE-QEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQ 74 Query: 436 ALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSE 495 L + K E L+++E + ++ ++M+ + + E K+ + E + + Sbjct: 75 RLPEQKEKMWEQDERLREKEERMRE------QKMWQQVEKMREKKKTQEEKMQEQEEKMQ 128 Query: 496 RVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQ 532 EE ++ +++ + + E E ++ Q Sbjct: 129 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 165 Score = 32.0 bits (71), Expect = 4.1 Identities = 31/159 (19%), Positives = 67/159 (42%), Gaps = 9/159 (5%) Query: 1011 ERERKWEQQLQEEQEQKRLQAE---AEEQKRPAEEQK--RQAEIERETSVRIYQYRRPVD 1065 ER R+ E++++EE+E R Q E +E+K +E+K Q E +E ++++ + Sbjct: 5 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 64 Query: 1066 SYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQR-RSKKEQ 1124 + E+ LP + K E + K Q+ M ++ + +K Q Sbjct: 65 EQEEKMWEQQR---LPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121 Query: 1125 VPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1163 E+++++ E ++ + W ++ +E Sbjct: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 160 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 63.9 bits (154), Expect = 1e-09 Identities = 57/263 (21%), Positives = 112/263 (42%), Gaps = 25/263 (9%) Query: 893 QEEERKRQERW-QKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 951 +E ER+R++R ++E DR + + ++++ + R+ + +++ E+E + D E Sbjct: 60 KERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE------- 112 Query: 952 SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIE 1011 R+ E + ++REG R + + +E D K+ + Q E Sbjct: 113 ------RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE 166 Query: 1012 RERKWEQQLQEEQEQKRLQAEAEEQKRPAE----------EQKRQAEIERETSVRIYQYR 1061 R+R+ E+ Q+E+E+++ + E E++R E E+ R+ E ERET + R Sbjct: 167 RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR 226 Query: 1062 RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQR-RS 1120 + D + E S TE D + ++ D+ Q R Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286 Query: 1121 KKEQVPSGAELERQQILQEMRKR 1143 ++ + E ER++ Q R+R Sbjct: 287 RQRRTERDRETERKRERQRERER 309 Score = 63.2 bits (152), Expect = 2e-09 Identities = 66/273 (24%), Positives = 117/273 (42%), Gaps = 26/273 (9%) Query: 892 DQEEERKRQERWQKEQDRLLQEKYQREQEKLRE-EWQRAKQEAE-RENSKYLDEELMVLS 949 D + ER+RQ +KE++R + QR+ E+ R+ E +R K E RE + ++E Sbjct: 144 DGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED 203 Query: 950 SNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEER---RQPQEEVVHE---DQGKK 1003 +S RE T T +E + +DRE R + ER +Q + E E ++ K+ Sbjct: 204 RHSERGRERERERET--ETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKE 261 Query: 1004 PQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP 1063 + + +R+R Q+ +E Q ++ Q E + +++RQ E ERE + R Sbjct: 262 RERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERER 321 Query: 1064 VDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKE 1123 + + E K + TE+D + G +R++++E Sbjct: 322 ERERERERQRETERDREKERERKRKRQTEMDRERNRQTGR-----------EGRRQAERE 370 Query: 1124 QVPSGAELERQQILQEMRKRTPLHNDNSWIRQR 1156 + E ER++ Q R+R D RQ+ Sbjct: 371 R-----ERERERDRQSAREREERERDRDRDRQK 398 Score = 56.6 bits (135), Expect = 2e-07 Identities = 49/196 (25%), Positives = 87/196 (44%), Gaps = 23/196 (11%) Query: 892 DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 951 ++E RKR+ ++E++R Q + +R++EK RE ++ + E +RE ++ E + Sbjct: 310 ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAER 369 Query: 952 SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIE 1011 RE A E + DR+ R E ER+ + + Sbjct: 370 ERE---RERERDRQSARERE-ERERDRDRDRQKERERQTEK------------------D 407 Query: 1012 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQK-RQAEIERETSVRIYQYRRPVDSYDIP 1070 R+ + E + Q E+E+ R E+ R E+QK R+ + ER+T + + R+ Y P Sbjct: 408 RDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNP 467 Query: 1071 KTEEASSGFLPGDRNK 1086 A SG + D N+ Sbjct: 468 PPRTARSGVVQSDPNR 483 Score = 56.2 bits (134), Expect = 2e-07 Identities = 51/218 (23%), Positives = 91/218 (41%), Gaps = 46/218 (21%) Query: 892 DQEEERKR-----QERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELM 946 D+E ER+R ++R QKE++R K QR E+ RE ++ +++ ERE + Sbjct: 259 DKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER------- 311 Query: 947 VLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQD 1006 E ++ +RE R E ER++ E +++ +K + Sbjct: 312 ------------------------ERNRKRERERERERERERQRETERDREKERERKRKR 347 Query: 1007 QLVIERER----------KWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVR 1056 Q ++RER + E++ + E+E+ R A E++ ++ RQ E ER+T Sbjct: 348 QTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKD 407 Query: 1057 IYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELD 1094 R + K E+ G G + + E D Sbjct: 408 RDGQRETEKQREREKDRESERGRERGREREKQKGRERD 445 Score = 48.1 bits (113), Expect = 6e-05 Identities = 37/164 (22%), Positives = 74/164 (45%), Gaps = 2/164 (1%) Query: 892 DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 951 ++E ER+RQ ++++++ + K +R+ E RE ++ +E R+ + + E + Sbjct: 322 ERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQS 381 Query: 952 SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEE--ERRQPQEEVVHEDQGKKPQDQLV 1009 + RE E DR+G R E+ ER + +E ++G++ + Q Sbjct: 382 AREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKG 441 Query: 1010 IERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1053 ER+R+ + Q +++KR R A Q++ R T Sbjct: 442 RERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPT 485 Score = 45.8 bits (107), Expect = 3e-04 Identities = 55/230 (23%), Positives = 89/230 (38%), Gaps = 22/230 (9%) Query: 977 DREGTRAGEEERRQPQEEVVHEDQGKKP---QDQLVIERERKWEQQLQEEQEQKRLQAEA 1033 DRE R E ERR+ + + E K+ + +R+R E+Q E+E++R Q + Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERER-QTDR 111 Query: 1034 EEQKRPAEEQKRQAEIERETSVRIYQYR-RPVDSY-------DIPKTEEASSGFLPGDRN 1085 E ++ +E+ RQ E ERET + R R D D K E + DR Sbjct: 112 ERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQT-----DRE 166 Query: 1086 KSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQ---EMRK 1142 + R T + N + + + +++ G E ER++ + E ++ Sbjct: 167 RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR 226 Query: 1143 RTPLHND--NSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQ 1190 +T D R+R +E S R E D R RQ Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQ 276 Score = 44.7 bits (104), Expect = 6e-04 Identities = 43/239 (17%), Positives = 94/239 (39%), Gaps = 11/239 (4%) Query: 324 VPAPLRKKKPDKHEDNRRSWASPVYTEADGTF-SRLFQKIYGENGSKSMSDVSAEDVQNL 382 +P +++P E RR + +ADG R QK K ++ + + Sbjct: 22 IPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETDRKRER 81 Query: 383 RQL--RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKS 440 R+ R+ + + + + ++++++ + + +DR++ + QK++E E E + Sbjct: 82 RREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETEREGERGRDR 141 Query: 441 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 500 + + +E +D E + ++ T R+R + E + E + Q R E+ Sbjct: 142 QTDGQRERERQRDAEKERERQTDRERQRQTERNRQKERER--------EKNRQERRERER 193 Query: 501 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVS 559 ++ S +RE TE + + + + + R R Q E R S Sbjct: 194 QREKENKTEDRHSERGRERERERETETETERKRQTDRERDRQRKTEREREKQAERERAS 252 Score = 38.1 bits (87), Expect = 0.058 Identities = 57/295 (19%), Positives = 110/295 (37%), Gaps = 24/295 (8%) Query: 331 KKPDKHEDNRRSWASPVYTEADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEM 390 K D+H + R TE + R + E + ++ E + E Sbjct: 200 KTEDRHSERGRERERERETETETERKRQTDR---ERDRQRKTEREREKQAERERASERET 256 Query: 391 QKIKSQLKEQDQ-----KWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSK 445 ++ K + +E+D+ + Q + + DR++ ++ ++ E + E +++ + +R+ K Sbjct: 257 ERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRK 316 Query: 446 TFKEMLQDRESQNQKSTVPSR------RRMYSFDDVLEEGKRPPTMTVSEASYQSERVEE 499 +E ++RE + Q+ T R +R + E ++ +A + ER E Sbjct: 317 RERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERE 376 Query: 500 KG--ATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQ--SPASLSSLRSRSTQMES 555 + + E + D ++E TE Q E+Q S R R E Sbjct: 377 RDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRER 436 Query: 556 TRVSASLPRSYRKTD------TVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWK 604 + R+TD R T V P P +++ + S P T WK Sbjct: 437 EKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWK 491 Score = 36.2 bits (82), Expect = 0.22 Identities = 44/197 (22%), Positives = 78/197 (39%), Gaps = 14/197 (7%) Query: 329 RKKKPDKHEDNRRSWASPVYTEADGTFSR-LFQKIYGENGSKSMSDVSAEDVQNLRQLRY 387 R +K ++ + R TE D R +K E + E + + R Sbjct: 313 RNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERE 372 Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447 E ++ + +E++++ +D + +DR+K +K ++ + E EKQ + R S+ Sbjct: 373 RERERDRQSAREREERERD---RDRDRQKERERQTEKDRDGQRETEKQREREKDRESERG 429 Query: 448 KEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGK-----RPPTMTVSEASYQSE-RVEEKG 501 +E + RE + QK R R + + PP T QS+ +G Sbjct: 430 RE--RGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRG 487 Query: 502 ATYPS--EIPKEDSTTF 516 + S E PK ST F Sbjct: 488 IRWKSSPEDPKAASTRF 504 Score = 33.9 bits (76), Expect = 1.1 Identities = 41/181 (22%), Positives = 77/181 (42%), Gaps = 12/181 (6%) Query: 969 WSEGSKSSDREGTRAGEEE--RRQPQEEVVHEDQGKKPQDQLVIERERKWE-QQLQEEQE 1025 W E + D R G +E RR+ + + G + ERER+ E +Q + E + Sbjct: 17 WVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETD 76 Query: 1026 QKRLQAEAEEQKRPAE---EQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPG 1082 +KR + +++ R + E++R E ERE + R+ + K E + G Sbjct: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETE-REG 135 Query: 1083 DRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRK 1142 +R + R T + ++ + Q + + R ++ + E ER++ QE R+ Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQ-----TDRERQRQTERNRQKEREREKNRQERRE 190 Query: 1143 R 1143 R Sbjct: 191 R 191 Score = 33.5 bits (75), Expect = 1.4 Identities = 30/172 (17%), Positives = 74/172 (43%), Gaps = 20/172 (11%) Query: 386 RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSK 445 R + +K +++ KE++++ + + + +DR+ + +++++ +E E+Q + +R ++ Sbjct: 113 RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTE 172 Query: 446 TFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYP 505 ++ ++RE Q+ R+R + + +R E+G Sbjct: 173 RNRQKEREREKNRQERRERERQR-------------------EKENKTEDRHSERGRERE 213 Query: 506 SEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTR 557 E E T ++ DR + Q ++ E+Q+ +S R E R Sbjct: 214 RERETETETERKRQTDR-ERDRQRKTEREREKQAERERASERETERDKERER 264 >gi|4503509 eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa [Homo sapiens] Length = 1382 Score = 62.8 bits (151), Expect = 2e-09 Identities = 87/415 (20%), Positives = 162/415 (39%), Gaps = 62/415 (14%) Query: 824 ESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTI 883 E L I +K++ + E + + LKN +++ +FE+ +P + Sbjct: 662 EELDPDFIMAKQVEQLEKEKKELQER------LKNQEKKIDYFERAKRLEEIPLIKSAY- 714 Query: 884 SAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDE 943 +E+ K + W+++++ + Q E+EK E R + E D Sbjct: 715 ---------EEQRIKDMDLWEQQEEERITTM-QLEREKALEHKNRMSRMLE-------DR 757 Query: 944 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003 +L V+ + + E L +E +E + E R +EERR E++ ++ Sbjct: 758 DLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRR 817 Query: 1004 PQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP 1063 ++Q++ ERE + + + +E+ R E ++ E +KRQ E+E E R + R Sbjct: 818 AEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERR 877 Query: 1064 VDSYDIPKTEEASSGFLPGDRNKS---RSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRS 1120 + + + + GDR+ R E D S + G + + G R Sbjct: 878 LGDSSLSRKDSRW-----GDRDSEGTWRKGPEAD--SEWRRGPPEKEWRRGEGRDEDRSH 930 Query: 1121 KKEQVPSGAELERQQILQEMRKRTP-LHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDN 1179 ++++ ER + L + R P L D+ + +R ++ P RRG D Sbjct: 931 RRDE-------ERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGP-------RRGPEEDR 976 Query: 1180 LDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPP 1234 S R +P W N D R PP+ ++ +R R+ PP Sbjct: 977 F-SRRGADDDRPSWRN-----------TDDDR-PPRRIADEDRGNWRHADDDRPP 1018 Score = 49.3 bits (116), Expect = 2e-05 Identities = 63/302 (20%), Positives = 122/302 (40%), Gaps = 94/302 (31%) Query: 894 EEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAK----------------------- 930 EEER RQE ++E++R+LQE Q +++ +RE ++ K Sbjct: 608 EEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPD 667 Query: 931 -----------------QEAERENSKYLD--------EELMVLSSNSMSLTTREPSLATW 965 QE + K +D EE+ ++ S ++ L W Sbjct: 668 FIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDL--W 725 Query: 966 EATWSEGSKSSDREGTRAGEEERRQPQ---------------EEVVHEDQGKKPQDQLVI 1010 E E + E +A E + R + + V+E++ K+ +++L Sbjct: 726 EQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAE 785 Query: 1011 ERERKWEQQLQEEQEQKRL----QAEAEEQKR-------PAEEQKRQAEIERETSVRIYQ 1059 ER + E++ ++ +E++R+ + E EEQ+R EE++R +RE +R YQ Sbjct: 786 ERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQ 845 Query: 1060 YRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRR 1119 R + K EE +R K + E+++ + + +G+ + S++ Sbjct: 846 ER-------VKKLEEV-------ERKKRQRELEIEERERRREEERR----LGDSSLSRKD 887 Query: 1120 SK 1121 S+ Sbjct: 888 SR 889 Score = 42.7 bits (99), Expect = 0.002 Identities = 43/200 (21%), Positives = 85/200 (42%), Gaps = 17/200 (8%) Query: 886 PSRWVWDQEEERKRQERW--QKEQDRLLQEKYQREQEKLREEWQRAKQ----EAERENSK 939 P W +E+E+ R+E W +E + ++ RE+E+ R+ R + E ER+ + Sbjct: 1175 PGGW---REKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRER 1231 Query: 940 YLDEELMVLSSNSMSLTTREPSLATWEATWSEGSK--SSDREGTRAGEEERRQPQEEVVH 997 +D E R P A ++W + S+ DR+ R ++RR +E Sbjct: 1232 DVDREDRFRRPRDEGGWRRGP--AEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDL 1289 Query: 998 EDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRP----AEEQKRQAEIERET 1053 D + L ERE + ++++ R++ ++ P + +++R + ERE Sbjct: 1290 RDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREG 1349 Query: 1054 SVRIYQYRRPVDSYDIPKTE 1073 +R D + +T+ Sbjct: 1350 EKEKASWRAEKDRESLRRTK 1369 Score = 30.8 bits (68), Expect = 9.2 Identities = 28/135 (20%), Positives = 57/135 (42%), Gaps = 18/135 (13%) Query: 383 RQLRYEE-MQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSK 441 RQ YEE +++ + +L E+ ++ + + + T +K++EE+ E+Q Sbjct: 768 RQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQ------ 821 Query: 442 RSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDD---VLEEGKRPPTMTVSEASYQSERVE 498 ML++RE + + + + + LEE +R E + R E Sbjct: 822 --------MLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRRE 873 Query: 499 EKGATYPSEIPKEDS 513 E+ S + ++DS Sbjct: 874 EERRLGDSSLSRKDS 888 >gi|4502923 calponin 3 [Homo sapiens] Length = 329 Score = 62.4 bits (150), Expect = 3e-09 Identities = 29/73 (39%), Positives = 46/73 (63%) Query: 86 DFRASLENGVLLCDLINKLKPGVIKKINRLSTPIAGLDNINVFLKACEQIGLKEAQLFHP 145 +F+ L++G++LC+LINKL+PG +KK+N S L+NI F+KA + G+K +F Sbjct: 47 NFQLGLKDGIILCELINKLQPGSVKKVNESSLNWPQLENIGNFIKAIQAYGMKPHDIFEA 106 Query: 146 GDLQDLSNRVTVK 158 DL + N V+ Sbjct: 107 NDLFENGNMTQVQ 119 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 62.4 bits (150), Expect = 3e-09 Identities = 147/730 (20%), Positives = 274/730 (37%), Gaps = 124/730 (16%) Query: 412 KDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYS 471 K RR SY D E R+ I ++ + RSS+ L+ ++S + +TV Sbjct: 67 KKRRISYVQD-----ENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATV-------- 113 Query: 472 FDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLP- 530 V E G +T + A+ + + PS E T K+ + T+ QL Sbjct: 114 ---VGENGSVLRRVTRAAAAAAAATM---ALAAPSSPTPESPTMLTKKPEDNHTQCQLVP 167 Query: 531 ------SQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSY----------------RK 568 S+ EQ L S + T SA+ P S R Sbjct: 168 VVEIGISERQNAEQHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARI 227 Query: 569 TDTVRLTSVV-TPRPFGSQTRG------------ISSLPRSYTM--DDAWKYN------- 606 +++ ++S++ TP+ Q G +S PR D W+ Sbjct: 228 LESITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILP 287 Query: 607 -------GDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPF 659 G D + ++ ++ +PSP L+ + + A +E V R S Sbjct: 288 DNFSTPTGSRTDSQSVRHSPIAPSSPSPQV------LAQKYSLVAKQESVVRRASRRLA- 340 Query: 660 SSLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSL 719 +++ AA+ + S L E + S Q+E + + + + G + Sbjct: 341 KKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNS 400 Query: 720 --DFGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKA 777 I P A+ +P+ Q D+ S + +++A+++ Sbjct: 401 WPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSEL 460 Query: 778 QETGHLVMDVRRYGKAGSPETKWIDAT------SGIYNSEKSSNLSVTTDFSESLQSSNI 831 E HL + + ++ +P + + + ++ +++ L T S+ S I Sbjct: 461 DEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFI 520 Query: 832 ESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPD----LPVPTISAPS 887 + + + K E L+NL+R+ + EQ V D L + Sbjct: 521 K-------RNTPLRMDPKEKERQRLENLRRKEEA-EQLRRQKVEEDKRRRLEEVKLKREE 572 Query: 888 RW---------VWDQEEERKRQ---------ERWQK-EQDRLLQEKYQREQ--EKLREEW 926 R V +EE+K+Q E+ +K +++RL +EK +++ +K+ E Sbjct: 573 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 632 Query: 927 QRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEE 986 R KQE E ++L +E + +E + RE R +E Sbjct: 633 ARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE 692 Query: 987 ERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQ-LQEEQE----QKRLQAEAEEQKRPAE 1041 R Q + E +Q ++ Q++ + E+ER+ EQ+ LQ E+E +K L+ + E+ +R E Sbjct: 693 RREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELE 752 Query: 1042 EQKRQAEIER 1051 E+K++ E +R Sbjct: 753 EKKKKEEQQR 762 Score = 60.5 bits (145), Expect = 1e-08 Identities = 54/192 (28%), Positives = 94/192 (48%), Gaps = 23/192 (11%) Query: 893 QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNS 952 +E E+ R+++ ++++ R L+E + +E+LR+ Q ++ + + K E + Sbjct: 545 EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDE 604 Query: 953 MSLTTREPSLATWEATWSEGSKSSDR-EGTRAGEEERR------QPQEEVVHED--QGKK 1003 + +E LA +A +K + E R EEE R Q +EE H++ Q KK Sbjct: 605 KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKK 664 Query: 1004 PQDQ-----------LVIERE---RKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEI 1049 ++Q L +RE R+ E++ QE +EQ+R + E EQ+R EQ+R+ E Sbjct: 665 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 724 Query: 1050 ERETSVRIYQYR 1061 ER + R Q R Sbjct: 725 ERLQAERELQER 736 Score = 58.2 bits (139), Expect = 5e-08 Identities = 45/148 (30%), Positives = 75/148 (50%), Gaps = 17/148 (11%) Query: 888 RWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAK----QEAERENSKYLDE 943 RW+ +EEER+ QE LLQ+K + EQE+LR+ + + +E ER + ++ Sbjct: 645 RWLQQEEEERRHQE--------LLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQ 696 Query: 944 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1003 E +E LA E + ++RE + E+ R +E++ E + KK Sbjct: 697 ERREQERREQERREQERQLAEQERRREQERLQAERE-LQEREKALRLQKEQLQRELEEKK 755 Query: 1004 PQDQLVIERERKWEQQLQEEQEQKRLQA 1031 ++ E++R E+QLQEEQE+K +A Sbjct: 756 KKE----EQQRLAERQLQEEQEKKAKEA 779 Score = 41.6 bits (96), Expect = 0.005 Identities = 37/181 (20%), Positives = 86/181 (47%), Gaps = 10/181 (5%) Query: 360 QKIYGENGSKSMSDVSA-----EDVQNLRQLRYEEMQKIKSQ-LKEQDQKWQDDLAKWKD 413 +K + +K M +V A E+ + LR L+ EE ++ + L+++ ++ Q+ L K + Sbjct: 617 EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAE 676 Query: 414 -RRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSF 472 +R + + +++++ER E E++ E+ ++ + + L ++E + ++ + + R + Sbjct: 677 AKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQER 736 Query: 473 DDVLEEGKRPPTMTVSEASYQSE--RVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLP 530 + L K + E + E R+ E+ E K A + VT ++Q P Sbjct: 737 EKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQE-KKAKEAAGASKALNVTVDVQSP 795 Query: 531 S 531 + Sbjct: 796 A 796 Score = 36.6 bits (83), Expect = 0.17 Identities = 30/169 (17%), Positives = 76/169 (44%), Gaps = 1/169 (0%) Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 447 ++M++++++ K++++ + + ++ + + LQKKKEE +E ++A E + + + Sbjct: 626 KKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQRE 685 Query: 448 KEML-QDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPS 506 +E Q+R Q ++ + + L E +R +A + + E+ Sbjct: 686 QERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKE 745 Query: 507 EIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMES 555 ++ +E K E + E QL + + + A S + + ++S Sbjct: 746 QLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQS 794 Score = 36.2 bits (82), Expect = 0.22 Identities = 32/135 (23%), Positives = 61/135 (45%), Gaps = 6/135 (4%) Query: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1070 ER+R + +EE EQ R Q E+++R EE K + E E ++ Q R V+ Sbjct: 534 ERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE---ERLRKVLQARERVEQMKEE 590 Query: 1071 KTEEASSGFLPGDRNKSRSTTE-LDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGA 1129 K ++ F D ++ E L + K K ++++ + +++ + Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 650 Query: 1130 ELER--QQILQEMRK 1142 E ER Q++LQ+ ++ Sbjct: 651 EEERRHQELLQKKKE 665 Score = 32.0 bits (71), Expect = 4.1 Identities = 39/227 (17%), Positives = 100/227 (44%), Gaps = 37/227 (16%) Query: 365 ENGSKSMSDVSAEDVQNLRQL-----RYEEMQKIK--------SQLKEQDQKWQDD-LAK 410 E+ + + +V + + LR++ R E+M++ K +Q+ E+ +K +++ LA+ Sbjct: 557 EDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAE 616 Query: 411 WKDRRKSYT---SDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRR 467 K ++K+ +++ ++++ EE + + + + +E+LQ ++ + Q+ R Sbjct: 617 EKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQE-----RL 671 Query: 468 RMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEI 527 R + E KR E Q R +E+ E + + ++R + Sbjct: 672 RKAA------EAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQE 725 Query: 528 QLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRL 574 +L ++ ++E R ++ +++ ++ L +K + RL Sbjct: 726 RLQAERELQE---------REKALRLQKEQLQRELEEKKKKEEQQRL 763 >gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens] Length = 1293 Score = 61.6 bits (148), Expect = 5e-09 Identities = 55/213 (25%), Positives = 91/213 (42%), Gaps = 31/213 (14%) Query: 881 PTISAPSRW----VWD----------------QEEERK----RQERWQKEQDRLLQEKYQ 916 PT S P+ W VWD Q E+ K QER + E +E+ + Sbjct: 690 PTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEER 749 Query: 917 REQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSS 976 + QE+LR + + + + E K +EE + +L + E + Sbjct: 750 KRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQ 809 Query: 977 DREGTRAGEEERRQPQEEVVHEDQGKKPQDQLV------IERERKWEQ-QLQEEQEQKRL 1029 E R EE RR+ +E E+ +K +++ E +R+ E+ +L+ E+E RL Sbjct: 810 QEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARL 869 Query: 1030 QAEAEEQKRPAEEQKRQAEIERETSVRIYQYRR 1062 + E EE+KR E +RQ E+ R+ + RR Sbjct: 870 RHEEEERKRKELEVQRQKELMRQRQQQQEALRR 902 Score = 58.9 bits (141), Expect = 3e-08 Identities = 69/335 (20%), Positives = 143/335 (42%), Gaps = 32/335 (9%) Query: 893 QEEERKRQERWQKEQDRLL-----QEKYQREQEKL------------REEWQRAKQEAER 935 +EEERKRQE +++Q+ +L +E+ +RE+E+L RE+ +++ E Sbjct: 745 EEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREE 804 Query: 936 ENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSK--SSDREGTRAGEEERRQPQE 993 E + +E L L R E +K + E R EE R + +E Sbjct: 805 EERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE 864 Query: 994 EVV---HEDQGKKPQDQLVIERERKWEQQLQEEQEQ-KRLQAEAEEQKRPAEEQKRQAEI 1049 E HE++ +K + +L ++R+++ +Q Q++QE +RLQ + ++Q+ + + Sbjct: 865 EAARLRHEEEERK-RKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTW 923 Query: 1050 ERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQ 1109 ++++ Q + + +I K EE L ++ + + + + + L Sbjct: 924 GQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSG 982 Query: 1110 IGNMTSSQRRSK---KEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVS 1166 GN++ +K + Q ++++QQ Q+ ++ +N+ ++ N S Sbjct: 983 WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGN----S 1038 Query: 1167 LPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFY 1201 + G + G S+ W N GF+ Sbjct: 1039 VWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFW 1073 Score = 47.0 bits (110), Expect = 1e-04 Identities = 58/272 (21%), Positives = 115/272 (42%), Gaps = 35/272 (12%) Query: 887 SRWVWDQEEERKRQE----RWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLD 942 ++W ++EE ++R E R ++E RL E+ +R++++L + Q+ ++ + L Sbjct: 842 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL- 900 Query: 943 EELMVLSSNSMSLTTREPSLATW-----------EATWS--EGSKSSDREGTRAGEEERR 989 L + PS +TW +AT S E K + + EE+RR Sbjct: 901 RRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 960 Query: 990 QPQEEVVHEDQGKKPQDQLV-----IERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQK 1044 Q +E + Q ++ Q Q + + + + L E Q+++ Q + ++Q++ +Q Sbjct: 961 QQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQP 1020 Query: 1045 RQAEIERETSVRIYQYRRPVDSYDI-PKTEEAS---SGFLPGDRNKSRSTTELDD----- 1095 +A +++ S + P + AS S K+ + DD Sbjct: 1021 NRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEV 1080 Query: 1096 ---YSTNKNGNNKYLDQIGNMTSSQRRSKKEQ 1124 STNKN NN L + +++ Q + +E+ Sbjct: 1081 GPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1112 Score = 34.7 bits (78), Expect = 0.64 Identities = 37/200 (18%), Positives = 83/200 (41%), Gaps = 22/200 (11%) Query: 388 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEE------------REEIE-- 433 ++++K K+ EQ+++ + AK ++ + +L++++EE REE E Sbjct: 721 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 780 Query: 434 ----KQALEKSKRSSKTFKEMLQDRESQNQKST---VPSRRRMYSFDDVLEEGKRPPTMT 486 ++AL + + + ++ E Q Q+ + RRR EE R Sbjct: 781 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 840 Query: 487 VSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSL 546 ++ + + E + + + +E + + E+R E+++ Q + Q +L Sbjct: 841 AAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL 900 Query: 547 RSRSTQMESTRVS-ASLPRS 565 R Q + +++ LP S Sbjct: 901 RRLQQQQQQQQLAQMKLPSS 920 Score = 32.7 bits (73), Expect = 2.4 Identities = 21/82 (25%), Positives = 43/82 (52%), Gaps = 6/82 (7%) Query: 382 LRQLRYEEMQKIKSQLK-EQDQKW--QDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALE 438 LR+L+ ++ Q+ +Q+K W Q + + + +++QK +EER E+Q E Sbjct: 900 LRRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEER---ERQLRE 956 Query: 439 KSKRSSKTFKEMLQDRESQNQK 460 + +R + + LQ ++ Q Q+ Sbjct: 957 EQRRQQRELMKALQQQQQQQQQ 978 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.311 0.126 0.360 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 54,105,566 Number of Sequences: 37866 Number of extensions: 2739905 Number of successful extensions: 39832 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 353 Number of HSP's successfully gapped in prelim test: 1222 Number of HSP's that attempted gapping in prelim test: 17003 Number of HSP's gapped (non-prelim): 11068 length of query: 1349 length of database: 18,247,518 effective HSP length: 114 effective length of query: 1235 effective length of database: 13,930,794 effective search space: 17204530590 effective search space used: 17204530590 T: 11 A: 40 X1: 16 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.8 bits) S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.