BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|122937446 von Willebrand factor C domain-containing protein 2-like [Homo sapiens] (222 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|122937446 von Willebrand factor C domain-containing protein 2... 506 e-144 gi|38348414 von Willebrand factor C domain containing 2 [Homo sa... 262 2e-70 gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens] 79 4e-15 gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] 71 6e-13 gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens] 70 1e-12 gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens] 69 4e-12 gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens] 69 4e-12 gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens] 69 4e-12 gi|108773804 Fraser syndrome 1 [Homo sapiens] 67 2e-11 gi|40353769 chordin-like 2 [Homo sapiens] 59 4e-09 gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] 57 1e-08 gi|37693519 BMP-binding endothelial regulator precursor protein ... 54 8e-08 gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] 50 2e-06 gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] 47 1e-05 gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] 47 1e-05 gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] 47 1e-05 gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] 47 1e-05 gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] 47 1e-05 gi|30089980 chordin [Homo sapiens] 45 5e-05 gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] 45 6e-05 gi|221316568 chordin-like 1 isoform 4 precursor [Homo sapiens] 44 1e-04 gi|169211819 PREDICTED: keratin associated protein [Homo sapiens] 42 3e-04 gi|239745811 PREDICTED: hypothetical protein XP_002343557 [Homo ... 42 3e-04 gi|169212026 PREDICTED: keratin associated protein [Homo sapiens] 42 4e-04 gi|239755778 PREDICTED: mucin 19, oligomeric [Homo sapiens] 42 5e-04 gi|239750280 PREDICTED: mucin 19, oligomeric [Homo sapiens] 42 5e-04 gi|239744589 PREDICTED: mucin 19 [Homo sapiens] 42 5e-04 gi|148833508 notch1 preproprotein [Homo sapiens] 41 0.001 gi|109150416 peroxidasin [Homo sapiens] 41 0.001 gi|148727298 keratin associated protein 10-6 [Homo sapiens] 41 0.001 >gi|122937446 von Willebrand factor C domain-containing protein 2-like [Homo sapiens] Length = 222 Score = 506 bits (1304), Expect = e-144 Identities = 222/222 (100%), Positives = 222/222 (100%) Query: 1 MALHIHEACILLLVIPGLVTSAAISHEDYPADEGDQISSNDNLIFDDYRGKGCVDDSGFV 60 MALHIHEACILLLVIPGLVTSAAISHEDYPADEGDQISSNDNLIFDDYRGKGCVDDSGFV Sbjct: 1 MALHIHEACILLLVIPGLVTSAAISHEDYPADEGDQISSNDNLIFDDYRGKGCVDDSGFV 60 Query: 61 YKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHG 120 YKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHG Sbjct: 61 YKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHG 120 Query: 121 KNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGPNCFAG 180 KNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGPNCFAG Sbjct: 121 KNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGPNCFAG 180 Query: 181 TTIIPAGIEVKVDECNICHCHNGDWWKPAQCSKRECQGKQTV 222 TTIIPAGIEVKVDECNICHCHNGDWWKPAQCSKRECQGKQTV Sbjct: 181 TTIIPAGIEVKVDECNICHCHNGDWWKPAQCSKRECQGKQTV 222 >gi|38348414 von Willebrand factor C domain containing 2 [Homo sapiens] Length = 325 Score = 262 bits (669), Expect = 2e-70 Identities = 108/181 (59%), Positives = 136/181 (75%), Gaps = 4/181 (2%) Query: 41 DNLIFDDYRGKGCVDDSGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKV 100 + ++ DYRGKGCVD+SGFVY +GE+F PG S CPC+C +GP+C QPECP++HP+C V Sbjct: 143 EEYVYPDYRGKGCVDESGFVYAIGEKFAPGPSACPCLCTEEGPLCAQPECPRLHPRCIHV 202 Query: 101 EHNGCCPECKEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNP 160 + + CCP+CKE KN+CE+ GK Y+ LEEF SPCE CRCE + EV C V+ C ECV+P Sbjct: 203 DTSQCCPQCKERKNYCEFRGKTYQTLEEFVVSPCERCRCEANGEVLCTVSACPQTECVDP 262 Query: 161 VYEPEQCCPVCKNGPNCFAGTTIIPAGIEVKVDECNICHC--HNGDW--WKPAQCSKREC 216 VYEP+QCCP+CKNGPNCFA T +IPAG EVK DEC ICHC G W + A C++ EC Sbjct: 263 VYEPDQCCPICKNGPNCFAETAVIPAGREVKTDECTICHCTYEEGTWRIERQAMCTRHEC 322 Query: 217 Q 217 + Sbjct: 323 R 323 >gi|209571521 cysteine rich BMP regulator 2 isoform 2 [Homo sapiens] Length = 814 Score = 78.6 bits (192), Expect = 4e-15 Identities = 60/172 (34%), Positives = 74/172 (43%), Gaps = 25/172 (14%) Query: 51 KGCVDDSGFVYKLGERFFPGH-SNCPCVCALDGPV-CDQPECPKIHPKCTKVEHNGCCPE 108 +GC +G Y GE F P + C C L+G + C+Q CP+ C E CCP Sbjct: 136 RGC-SQNGQTYGNGETFSPDACTTCRC---LEGTITCNQKPCPR--GPCP--EPGACCPH 187 Query: 109 CKEVKNFCEYHGKNYKILEEFKPS--PCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQ 166 CK C+Y G+ Y+ F S PC C C S V C+ C C PV P Sbjct: 188 CKPG---CDYEGQLYEEGVTFLSSSNPCLQCTCLRSR-VRCMALKCPPSPCPEPVLRPGH 243 Query: 167 CCPVCKNGPNCFAGTTIIPAGIE--VKVDECNICHCHNGDWWKPAQCSKREC 216 CCP C+ C G + G E D C IC C G QC +REC Sbjct: 244 CCPTCQ---GCTEGGSHWEHGQEWTTPGDPCRICRCLEGH----IQCRQREC 288 Score = 71.2 bits (173), Expect = 6e-13 Identities = 45/145 (31%), Positives = 52/145 (35%), Gaps = 16/145 (11%) Query: 76 CVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKP--SP 133 CVC P C CP + CCP C C YH + Y + F SP Sbjct: 447 CVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDS----CTYHSQVYANGQNFTDADSP 502 Query: 134 CEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGPNCFAGTTIIPAG--IEVK 191 C C C+ V C + DC C P P QCCP C P+C + G Sbjct: 503 CHACHCQDGT-VTCSLVDCPPTTCARPQSGPGQCCPRC---PDCILEEEVFVDGESFSHP 558 Query: 192 VDECNICHCHNGDWWKPAQCSKREC 216 D C C C G A C R C Sbjct: 559 RDPCQECRCQEGH----AHCQPRPC 579 Score = 57.8 bits (138), Expect = 7e-09 Identities = 43/152 (28%), Positives = 60/152 (39%), Gaps = 17/152 (11%) Query: 57 SGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFC 116 +G ++ GE G C CA C+ CP + + CCP C + C Sbjct: 313 NGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVC----DGC 368 Query: 117 EYHGKNYKILEEFKPSP---CEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKN 173 EY G Y+ E F+ C C C+ + EV C +C V C P Q CP C+ Sbjct: 369 EYQGHQYQSQETFRLQERGLCVRCSCQ-AGEVSCEEQECPVTPCALPA-SGRQLCPACEL 426 Query: 174 GPNCFAGTTIIPAGIEVKVD--ECNICHCHNG 203 FA G++ + D C C C +G Sbjct: 427 DGEEFA------EGVQWEPDGRPCTACVCQDG 452 Score = 56.2 bits (134), Expect = 2e-08 Identities = 45/171 (26%), Positives = 68/171 (39%), Gaps = 18/171 (10%) Query: 51 KGCVDDSGFVYKLGERFFPGHSNCPCVCALDGPV-CDQPECPKIHPKCTKVEHNGCCPEC 109 +GC + G ++ G+ + C L+G + C Q EC + P + CCP C Sbjct: 249 QGCTE-GGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVC 307 Query: 110 KEVKNFCEYHGKNYKILEEF-KPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCC 168 + C +G+ ++ E PC CRC + V C C C +P P QCC Sbjct: 308 ----DGCFLNGREHRSGEPVGSGDPCSHCRCA-NGSVQCEPLPCPPVPCRHPGKIPGQCC 362 Query: 169 PVCKNGPNCFAGTTIIPAGIEVKVDE---CNICHCHNGDWWKPAQCSKREC 216 PVC C + ++ E C C C G+ C ++EC Sbjct: 363 PVC---DGCEYQGHQYQSQETFRLQERGLCVRCSCQAGE----VSCEEQEC 406 Score = 56.2 bits (134), Expect = 2e-08 Identities = 40/120 (33%), Positives = 47/120 (39%), Gaps = 11/120 (9%) Query: 60 VYKLGERFFPGHSNCP-CVCALDGPVCDQPECPKIHPKCTKVEHNGCCP-ECKEVKNFCE 117 V+ GE F C C C C CP+ C CCP +C C Sbjct: 548 VFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRA--PCAHPLPGTCCPNDCSG----CA 601 Query: 118 YHGKNYKILEEFK-PS-PCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGP 175 + GK Y +F PS PC CRC N V C+ C C PV P +CCP C P Sbjct: 602 FGGKEYPSGADFPHPSDPCRLCRCLSGN-VQCLARRCVPLPCPEPVLLPGECCPQCPAAP 660 >gi|209571519 cysteine rich BMP regulator 2 isoform 1 [Homo sapiens] Length = 1503 Score = 71.2 bits (173), Expect = 6e-13 Identities = 45/145 (31%), Positives = 52/145 (35%), Gaps = 16/145 (11%) Query: 76 CVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKP--SP 133 CVC P C CP + CCP C C YH + Y + F SP Sbjct: 389 CVCQDGVPKCGAVLCPPAPCQHPTQPPGACCPSCDS----CTYHSQVYANGQNFTDADSP 444 Query: 134 CEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGPNCFAGTTIIPAG--IEVK 191 C C C+ V C + DC C P P QCCP C P+C + G Sbjct: 445 CHACHCQDGT-VTCSLVDCPPTTCARPQSGPGQCCPRC---PDCILEEEVFVDGESFSHP 500 Query: 192 VDECNICHCHNGDWWKPAQCSKREC 216 D C C C G A C R C Sbjct: 501 RDPCQECRCQEGH----AHCQPRPC 521 Score = 67.0 bits (162), Expect = 1e-11 Identities = 52/172 (30%), Positives = 74/172 (43%), Gaps = 27/172 (15%) Query: 49 RGKGCVDDSGFVYKLGERFFPGHSNCP-CVCALDGPVCDQPECPKIHPKCTKVEHNGCCP 107 R +GC+ G + G R+ P S C CVC C + +C + + H+ CCP Sbjct: 892 RCRGCLAH-GEEHPEGSRWVPPDSACSSCVCHEGVVTCARIQCISSCAQPRQGPHD-CCP 949 Query: 108 ECKEVKNFCEYHGKNYKILEEFKPS--PCEWCRCEPSNE----VHC------VVADCAVP 155 +C + CE+ G+ Y+ E F+P PCE C CEP E + C + C Sbjct: 950 QCSD----CEHEGRKYEPGESFQPGADPCEVCICEPQPEGPPSLRCHRRQCPSLVGCPPS 1005 Query: 156 ECVNPVYEPEQCCPVCKNG-PNCFAGTTIIPAGIEV-KVDECNICHCHNGDW 205 + + P P+ CCP C NC G G E+ D C C C + W Sbjct: 1006 QLLPP--GPQHCCPTCAEALSNCSEGL----LGSELAPPDPCYTCQCQDLTW 1051 Score = 64.3 bits (155), Expect = 8e-11 Identities = 49/172 (28%), Positives = 71/172 (41%), Gaps = 23/172 (13%) Query: 52 GCVDDSGFVYKLGERFFPGHSNCP-CVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECK 110 GC+ G + GERF + C C+C C+ C C CCP+C Sbjct: 661 GCLYQ-GKEFASGERFPSPTAACHLCLCWEGSVSCEPKACAPA--LCPFPARGDCCPDC- 716 Query: 111 EVKNFCEYHGKNYKILEEFKP--SPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCC 168 + CEY G++Y +EF PC C C V C C P C +P+ CC Sbjct: 717 ---DGCEYLGESYLSNQEFPDPREPCNLCTCL-GGFVTCGRRPCEPPGCSHPLIPSGHCC 772 Query: 169 PVCK----NGPNCFAGTTIIPAGIEVKVDECNICHCHNGDWWKPAQCSKREC 216 P C+ +G +G T +P ++ C++C C G +C K+ C Sbjct: 773 PTCQGCRYHGVTTASGET-LPDPLD---PTCSLCTCQEGS----MRCQKKPC 816 Score = 61.2 bits (147), Expect = 7e-10 Identities = 44/161 (27%), Positives = 60/161 (37%), Gaps = 19/161 (11%) Query: 64 GERFFPGHSNCP-CVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKN 122 GE F +C C C C + +CP + K E CCP C+ C HG+ Sbjct: 847 GEEFEGPAGSCEWCRCQAGQVSCVRLQCPPLPCKLQVTERGSCCPRCRG----CLAHGEE 902 Query: 123 YKILEEFKP--SPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKN----GPN 176 + + P S C C C V C C + C P P CCP C + G Sbjct: 903 HPEGSRWVPPDSACSSCVCH-EGVVTCARIQC-ISSCAQPRQGPHDCCPQCSDCEHEGRK 960 Query: 177 CFAGTTIIPAGIEVKVDECNICHCHNGDWWKPA-QCSKREC 216 G + P D C +C C P+ +C +R+C Sbjct: 961 YEPGESFQPG-----ADPCEVCICEPQPEGPPSLRCHRRQC 996 Score = 57.8 bits (138), Expect = 7e-09 Identities = 36/112 (32%), Positives = 46/112 (41%), Gaps = 16/112 (14%) Query: 107 PECKEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQ 166 P C+ C +G+ Y E F P C CRC + V C C+ C+ P + Sbjct: 133 PHCRG----CSQNGQTYGNGETFSPDACTTCRCL-TGAVQCQGPSCSELNCLESCTPPGE 187 Query: 167 CCPVCKNGPNCFAGTTIIPAGIE--VKVDECNICHCHNGDWWKPAQCSKREC 216 CCP+C C G + G E D C IC C G QC +REC Sbjct: 188 CCPIC-----CTEGGSHWEHGQEWTTPGDPCRICRCLEGH----IQCRQREC 230 Score = 57.8 bits (138), Expect = 7e-09 Identities = 43/152 (28%), Positives = 60/152 (39%), Gaps = 17/152 (11%) Query: 57 SGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFC 116 +G ++ GE G C CA C+ CP + + CCP C + C Sbjct: 255 NGREHRSGEPVGSGDPCSHCRCANGSVQCEPLPCPPVPCRHPGKIPGQCCPVC----DGC 310 Query: 117 EYHGKNYKILEEFKPSP---CEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKN 173 EY G Y+ E F+ C C C+ + EV C +C V C P Q CP C+ Sbjct: 311 EYQGHQYQSQETFRLQERGLCVRCSCQ-AGEVSCEEQECPVTPCALPA-SGRQLCPACEL 368 Query: 174 GPNCFAGTTIIPAGIEVKVD--ECNICHCHNG 203 FA G++ + D C C C +G Sbjct: 369 DGEEFA------EGVQWEPDGRPCTACVCQDG 394 Score = 57.4 bits (137), Expect = 1e-08 Identities = 44/169 (26%), Positives = 66/169 (39%), Gaps = 17/169 (10%) Query: 53 CVDDSGFVYKLGERFFPGHSNCPCVCALDGPV-CDQPECPKIHPKCTKVEHNGCCPECKE 111 C + G ++ G+ + C L+G + C Q EC + P + CCP C Sbjct: 192 CCTEGGSHWEHGQEWTTPGDPCRICRCLEGHIQCRQRECASLCPYPARPLPGTCCPVC-- 249 Query: 112 VKNFCEYHGKNYKILEEF-KPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPV 170 + C +G+ ++ E PC CRC + V C C C +P P QCCPV Sbjct: 250 --DGCFLNGREHRSGEPVGSGDPCSHCRCA-NGSVQCEPLPCPPVPCRHPGKIPGQCCPV 306 Query: 171 CKNGPNCFAGTTIIPAGIEVKVDE---CNICHCHNGDWWKPAQCSKREC 216 C C + ++ E C C C G+ C ++EC Sbjct: 307 C---DGCEYQGHQYQSQETFRLQERGLCVRCSCQAGE----VSCEEQEC 348 Score = 55.8 bits (133), Expect = 3e-08 Identities = 40/122 (32%), Positives = 47/122 (38%), Gaps = 11/122 (9%) Query: 60 VYKLGERFFPGHSNCP-CVCALDGPVCDQPECPKIHPKCTKVEHNGCCP-ECKEVKNFCE 117 V+ GE F C C C C CP+ C CCP +C C Sbjct: 490 VFVDGESFSHPRDPCQECRCQEGHAHCQPRPCPRA--PCAHPLPGTCCPNDCSG----CA 543 Query: 118 YHGKNYKILEEFK-PS-PCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGP 175 + GK Y +F PS PC CRC N V C+ C C PV P +CCP C Sbjct: 544 FGGKEYPSGADFPHPSDPCRLCRCLSGN-VQCLARRCVPLPCPEPVLLPGECCPQCPAPA 602 Query: 176 NC 177 C Sbjct: 603 GC 604 Score = 45.4 bits (106), Expect = 4e-05 Identities = 33/125 (26%), Positives = 44/125 (35%), Gaps = 11/125 (8%) Query: 63 LGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHN----GCCPECKEVKNFCEY 118 LG P C C +C CP++ C E + CCP C+ C + Sbjct: 1031 LGSELAPPDPCYTCQCQDLTWLCIHQACPEL--SCPLSERHTPPGSCCPVCRAPTQSCVH 1088 Query: 119 HGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPEC---VNPVYEPEQCCPVCKNGP 175 G+ E + C C C + V C C+ C P P CCP C P Sbjct: 1089 QGREVASGERWTVDTCTSCSC-MAGTVRCQSQRCSPLSCGPDKAPALSPGSCCPRCLPRP 1147 Query: 176 -NCFA 179 +C A Sbjct: 1148 ASCMA 1152 >gi|114431244 von Willebrand factor C and EGF domains [Homo sapiens] Length = 955 Score = 70.1 bits (170), Expect = 1e-12 Identities = 52/172 (30%), Positives = 75/172 (43%), Gaps = 19/172 (11%) Query: 52 GC-VDDSGFVYKLGERFFPGHSNCPCVCALDGPV-CDQPECPKIHPKCTKVEHNGCCPEC 109 GC +DD+G + +G+ + PG C+C DG V C + +C P ++ CCP+C Sbjct: 567 GCSLDDNGVEFPIGQIWSPGDPCELCICQADGSVSCKRTDCVDSCPHPIRIP-GQCCPDC 625 Query: 110 KEVKNFCEYHGKNYKILEEFKP--SPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQC 167 C Y G+ + E F PC C C V C DC + C P + +C Sbjct: 626 SA---GCTYTGRIFYNNETFPSVLDPCLSCIC-LLGSVACSPVDCPI-TCTYPFHPDGEC 680 Query: 168 CPVCKNGPNC-FAGTTIIPAGIEVKVDE-CNICHCHNGDWWKPAQCSKRECQ 217 CPVC+ +C + G + + DE C C C G+ C K CQ Sbjct: 681 CPVCR---DCNYEGRKVANGQVFTLDDEPCTRCTCQLGE----VSCEKVPCQ 725 Score = 62.4 bits (150), Expect = 3e-10 Identities = 54/179 (30%), Positives = 69/179 (38%), Gaps = 27/179 (15%) Query: 52 GCVDDSGFVYKLGERFFPGHSNCP-CVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECK 110 GC SG V G+ F P + NC CVC C PECP C CC C Sbjct: 442 GCFH-SGVVRAEGDVFSPPNENCTVCVCLAGNVSCISPECPS--GPCQTPPQTDCC-TCV 497 Query: 111 EVKNFCEYHGKNYKILEEFK--PSPCEWCRCEPSNEVHCVVADCAVPECVNPVYE----P 164 V+ C +HG+ Y F C C C+ + EV C C PE P E P Sbjct: 498 PVR--CYFHGRWYADGAVFSGGGDECTTCVCQ-NGEVECSFMPC--PELACPREEWRLGP 552 Query: 165 EQCCPVCKNGPNCFAGTTIIPAGIEVKV-------DECNICHCHNGDWWKPAQCSKREC 216 QCC C+ P G ++ G+E + D C +C C C + +C Sbjct: 553 GQCCFTCQE-PTPSTGCSLDDNGVEFPIGQIWSPGDPCELCICQADG---SVSCKRTDC 607 Score = 57.0 bits (136), Expect = 1e-08 Identities = 50/170 (29%), Positives = 64/170 (37%), Gaps = 25/170 (14%) Query: 61 YKLGERFFPGHSNCP-CVCALDGPVCDQPECPKIHPKCTKVEHN----GCCPECKEV--K 113 Y G F G C CVC C CP++ C + E CC C+E Sbjct: 508 YADGAVFSGGGDECTTCVCQNGEVECSFMPCPEL--ACPREEWRLGPGQCCFTCQEPTPS 565 Query: 114 NFCEY--HGKNYKILEEFKPS-PCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPV 170 C +G + I + + P PCE C C+ V C DC V C +P+ P QCCP Sbjct: 566 TGCSLDDNGVEFPIGQIWSPGDPCELCICQADGSVSCKRTDC-VDSCPHPIRIPGQCCPD 624 Query: 171 CKNG----PNCFAGTTIIPAGIEVKVDECNICHCHNGDWWKPAQCSKREC 216 C G F P+ +D C C C G CS +C Sbjct: 625 CSAGCTYTGRIFYNNETFPS----VLDPCLSCICLLGS----VACSPVDC 666 >gi|34147715 chordin-like 1 isoform 3 precursor [Homo sapiens] Length = 456 Score = 68.6 bits (166), Expect = 4e-12 Identities = 45/139 (32%), Positives = 62/139 (44%), Gaps = 30/139 (21%) Query: 61 YKLGERFFP-----GHSNCP-CVCALDGPV-CDQPECPKIHPKCTKVEH--NGCCPEC-- 109 Y++GER+ P G C C+C+ +G V C + CP +H C H + CCP C Sbjct: 44 YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH--CLSPVHIPHLCCPRCPD 101 Query: 110 -------KEVKNFCEYHGKNYKILEEF---------KPSPCEWCRCEPSNEVHCVVADCA 153 K CEY+G Y+ E F +P+ C C C N V+C + C Sbjct: 102 SLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGN-VYCGLKTCP 160 Query: 154 VPECVNPVYEPEQCCPVCK 172 C PV P+ CC VC+ Sbjct: 161 KLTCAFPVSVPDSCCRVCR 179 Score = 45.4 bits (106), Expect = 4e-05 Identities = 32/139 (23%), Positives = 50/139 (35%), Gaps = 30/139 (21%) Query: 104 GCCPECKEVKNFCEYHGKNYKILEEFKP--SP-----CEWCRCEPSNEVHCVVADCAVPE 156 G + K + +C + K Y++ E + P P C C C + V C C Sbjct: 25 GKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH 84 Query: 157 CVNPVYEPEQCCPVCK-----------------NGPNCFAGTTIIPAGI--EVKVDECNI 197 C++PV+ P CCP C NG G + G+ + ++C Sbjct: 85 CLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQ 144 Query: 198 CHCHNGDWWKPAQCSKREC 216 C C G+ C + C Sbjct: 145 CSCSEGN----VYCGLKTC 159 >gi|221316563 chordin-like 1 isoform 2 precursor [Homo sapiens] Length = 457 Score = 68.6 bits (166), Expect = 4e-12 Identities = 45/139 (32%), Positives = 62/139 (44%), Gaps = 30/139 (21%) Query: 61 YKLGERFFP-----GHSNCP-CVCALDGPV-CDQPECPKIHPKCTKVEH--NGCCPEC-- 109 Y++GER+ P G C C+C+ +G V C + CP +H C H + CCP C Sbjct: 44 YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH--CLSPVHIPHLCCPRCPD 101 Query: 110 -------KEVKNFCEYHGKNYKILEEF---------KPSPCEWCRCEPSNEVHCVVADCA 153 K CEY+G Y+ E F +P+ C C C N V+C + C Sbjct: 102 SLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGN-VYCGLKTCP 160 Query: 154 VPECVNPVYEPEQCCPVCK 172 C PV P+ CC VC+ Sbjct: 161 KLTCAFPVSVPDSCCRVCR 179 Score = 45.4 bits (106), Expect = 4e-05 Identities = 32/139 (23%), Positives = 50/139 (35%), Gaps = 30/139 (21%) Query: 104 GCCPECKEVKNFCEYHGKNYKILEEFKP--SP-----CEWCRCEPSNEVHCVVADCAVPE 156 G + K + +C + K Y++ E + P P C C C + V C C Sbjct: 25 GKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH 84 Query: 157 CVNPVYEPEQCCPVCK-----------------NGPNCFAGTTIIPAGI--EVKVDECNI 197 C++PV+ P CCP C NG G + G+ + ++C Sbjct: 85 CLSPVHIPHLCCPRCPDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQ 144 Query: 198 CHCHNGDWWKPAQCSKREC 216 C C G+ C + C Sbjct: 145 CSCSEGN----VYCGLKTC 159 >gi|221316561 chordin-like 1 isoform 1 precursor [Homo sapiens] Length = 458 Score = 68.6 bits (166), Expect = 4e-12 Identities = 45/140 (32%), Positives = 62/140 (44%), Gaps = 31/140 (22%) Query: 61 YKLGERFFP-----GHSNCP-CVCALDGPV-CDQPECPKIHPKCTKVEH--NGCCPECKE 111 Y++GER+ P G C C+C+ +G V C + CP +H C H + CCP C E Sbjct: 44 YRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH--CLSPVHIPHLCCPRCPE 101 Query: 112 ----------VKNFCEYHGKNYKILEEF---------KPSPCEWCRCEPSNEVHCVVADC 152 CEY+G Y+ E F +P+ C C C N V+C + C Sbjct: 102 DSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCTQCSCSEGN-VYCGLKTC 160 Query: 153 AVPECVNPVYEPEQCCPVCK 172 C PV P+ CC VC+ Sbjct: 161 PKLTCAFPVSVPDSCCRVCR 180 Score = 45.1 bits (105), Expect = 5e-05 Identities = 32/140 (22%), Positives = 50/140 (35%), Gaps = 31/140 (22%) Query: 104 GCCPECKEVKNFCEYHGKNYKILEEFKP--SP-----CEWCRCEPSNEVHCVVADCAVPE 156 G + K + +C + K Y++ E + P P C C C + V C C Sbjct: 25 GKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH 84 Query: 157 CVNPVYEPEQCCPVCK------------------NGPNCFAGTTIIPAGI--EVKVDECN 196 C++PV+ P CCP C NG G + G+ + ++C Sbjct: 85 CLSPVHIPHLCCPRCPEDSLPPVNNKVTSKSCEYNGTTYQHGELFVAEGLFQNRQPNQCT 144 Query: 197 ICHCHNGDWWKPAQCSKREC 216 C C G+ C + C Sbjct: 145 QCSCSEGN----VYCGLKTC 160 >gi|108773804 Fraser syndrome 1 [Homo sapiens] Length = 4011 Score = 66.6 bits (161), Expect = 2e-11 Identities = 43/139 (30%), Positives = 58/139 (41%), Gaps = 10/139 (7%) Query: 84 VCDQPECPKIHPKCTKVEHNGCCPEC-KEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPS 142 VC P+C + ++ N CCPEC C + K ++ E+ SPC C C Sbjct: 62 VCRNPQCAFEKGEVLQIAANQCCPECVLRTPGSCHHEKKIHEHGTEWASSPCSVCSCN-H 120 Query: 143 NEVHCVVADCAVPECVNP--VYEPE-QCCPVCKN-GPNCFAGTTIIPAGIEVKVDECNIC 198 EV C C C + + PE CCPVC G C + G + ++ C C Sbjct: 121 GEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCVGLGKPCSYEGHVFQDGEDWRLSRCAKC 180 Query: 199 HCHNGDWWKPAQCSKRECQ 217 C NG AQC +CQ Sbjct: 181 LCRNG----VAQCFTAQCQ 195 Score = 64.7 bits (156), Expect = 6e-11 Identities = 47/174 (27%), Positives = 74/174 (42%), Gaps = 19/174 (10%) Query: 57 SGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVE-----HNGCCPECKE 111 +G VY+ GE++ ++ C+C C + C + +C K + H CC EC Sbjct: 224 AGQVYEHGEQWSE-NACTTCICDRGEVRCHKQACLPL--RCGKGQSRARRHGQCCEECVS 280 Query: 112 VKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNP---VYEPEQCC 168 C Y G E +K S CE+C C+ +V C +CA EC ++ +CC Sbjct: 281 PAGSCSYDGVVRYQDEMWKGSACEFCMCD-HGQVTCQTGECAKVECARDEELIHLDGKCC 339 Query: 169 PVC--KNGPNCFAGTTIIPAGIEVKVDECNICHCHNGDWWKPAQCSKRECQGKQ 220 P C +NG + T G + + + G+ W+ C EC+G Q Sbjct: 340 PECISRNGYCVYEET-----GEFMSSNASEVKRIPEGEKWEDGPCKVCECRGAQ 388 Score = 61.2 bits (147), Expect = 7e-10 Identities = 42/154 (27%), Positives = 65/154 (42%), Gaps = 15/154 (9%) Query: 72 SNCPC-VCALD-GPV-CDQPECPKI---HPKCTKVEHNGCCPECKEVKNFCEYHGKNYKI 125 ++ PC VC+ + G V C CP + H + + CCP C + C Y G ++ Sbjct: 109 ASSPCSVCSCNHGEVRCTPQPCPPLSCGHQELAFIPEGSCCPVCVGLGKPCSYEGHVFQD 168 Query: 126 LEEFKPSPCEWCRCEPSNEVHCVVADCAVPEC---VNPVYEPEQCCPVCKNGPNCFAGTT 182 E+++ S C C C + C A C C V P +CCP C + +C A Sbjct: 169 GEDWRLSRCAKCLCR-NGVAQCFTAQCQPLFCNQDETVVRVPGKCCPQC-SARSCSAAGQ 226 Query: 183 IIPAGIEVKVDECNICHCHNGDWWKPAQCSKREC 216 + G + + C C C G+ +C K+ C Sbjct: 227 VYEHGEQWSENACTTCICDRGE----VRCHKQAC 256 Score = 46.2 bits (108), Expect = 2e-05 Identities = 28/95 (29%), Positives = 42/95 (44%), Gaps = 12/95 (12%) Query: 129 FKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYE-----PEQCCPVC--KNGPNCFAGT 181 +KP C+ CRC + V C A C P+C E QCCP C + +C Sbjct: 41 WKPDSCQSCRCH-GDIVICKPAVCRNPQCAFEKGEVLQIAANQCCPECVLRTPGSCHHEK 99 Query: 182 TIIPAGIEVKVDECNICHCHNGDWWKPAQCSKREC 216 I G E C++C C++G+ +C+ + C Sbjct: 100 KIHEHGTEWASSPCSVCSCNHGE----VRCTPQPC 130 Score = 28.1 bits (61), Expect = 6.2 Identities = 32/147 (21%), Positives = 48/147 (32%), Gaps = 43/147 (29%) Query: 64 GERFFPGHSNCPC-VCALDGP--VCDQPECP-------------KIHPKCTKVEHNGCCP 107 GE++ G PC VC G C +P CP + P CT V + C Sbjct: 371 GEKWEDG----PCKVCECRGAQVTCYEPSCPPCPVGTLALEVKGQCCPDCTSVHCHPDCL 426 Query: 108 ECKEVKNFCEYHGKNYKILEE----------FKPSPCEWCRCEPSNEVHCVVADCA---- 153 C + + C+ K+L+ F + C+P +C+ Sbjct: 427 TCSQSPDHCDLCQDPTKLLQNGWCVHSCGLGFYQAGSLCLACQPQCSTCTSGLECSSCQP 486 Query: 154 ---------VPECVNPVYEPEQCCPVC 171 VP C + Y+ C VC Sbjct: 487 PLLMRHGQCVPTCGDGFYQDRHSCAVC 513 >gi|40353769 chordin-like 2 [Homo sapiens] Length = 451 Score = 58.5 bits (140), Expect = 4e-09 Identities = 38/141 (26%), Positives = 56/141 (39%), Gaps = 32/141 (22%) Query: 64 GERFFPGHSNCP------------CVCALDGPV-CDQPECPKIHPKCTKVEHNGCCPECK 110 G+R+ PG S P C C+ V C + CP +H E CCP+C Sbjct: 37 GKRYSPGESWHPYLEPQGLMYCLRCTCSEGAHVSCYRLHCPPVHCPQPVTEPQQCCPKCV 96 Query: 111 EVKN---------FCEYHGKNYKILEEFK---------PSPCEWCRCEPSNEVHCVVADC 152 E C+++G Y+ E F P+ C C C +++C + C Sbjct: 97 EPHTPSGLRAPPKSCQHNGTMYQHGEIFSAHELFPSRLPNQCVLCSCT-EGQIYCGLTTC 155 Query: 153 AVPECVNPVYEPEQCCPVCKN 173 P C P+ P+ CC CK+ Sbjct: 156 PEPGCPAPLPLPDSCCQACKD 176 Score = 50.8 bits (120), Expect = 9e-07 Identities = 31/100 (31%), Positives = 39/100 (39%), Gaps = 19/100 (19%) Query: 115 FCEYHGKNYKILEEFKP-------SPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQC 167 FC +HGK Y E + P C C C V C C C PV EP+QC Sbjct: 32 FCLFHGKRYSPGESWHPYLEPQGLMYCLRCTCSEGAHVSCYRLHCPPVHCPQPVTEPQQC 91 Query: 168 CPVCKNGPNCFAGTTIIPAGIEVKVDECNICHCHNGDWWK 207 CP C P+ P+G+ C HNG ++ Sbjct: 92 CPKCVE-PH-------TPSGLRAPPKSCQ----HNGTMYQ 119 Score = 31.6 bits (70), Expect = 0.56 Identities = 19/67 (28%), Positives = 24/67 (35%), Gaps = 9/67 (13%) Query: 113 KNFCEYHGKNYK-------ILEEFKPSPCEWCRCEPSNEVHCVVADCAVP-ECVNPVYEP 164 K C + GK Y F P PC C CE + C C C +P Sbjct: 249 KKACVHGGKTYSHGEVWHPAFRAFGPLPCILCTCEDGRQ-DCQRVTCPTEYPCRHPEKVA 307 Query: 165 EQCCPVC 171 +CC +C Sbjct: 308 GKCCKIC 314 >gi|10092639 cysteine-rich motor neuron 1 [Homo sapiens] Length = 1036 Score = 57.4 bits (137), Expect = 1e-08 Identities = 33/123 (26%), Positives = 46/123 (37%), Gaps = 6/123 (4%) Query: 53 CVDDSGFVYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKE- 111 C +D G ++ E + P C+C C CP + + + CCP C E Sbjct: 753 CKNDEGDIFLAAESWKPDVCTS-CICIDSVISCFSESCPSVSCERPVLRKGQCCPYCIED 811 Query: 112 ---VKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCC 168 K C + GK Y E + C C C + C C CV P+ CC Sbjct: 812 TIPKKVVCHFSGKAYADEERWDLDSCTHCYCLQGQTL-CSTVSCPPLPCVEPINVEGSCC 870 Query: 169 PVC 171 P+C Sbjct: 871 PMC 873 Score = 57.0 bits (136), Expect = 1e-08 Identities = 46/177 (25%), Positives = 63/177 (35%), Gaps = 30/177 (16%) Query: 64 GERFFPGHS----NCP-CVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKE------- 111 GE F G + +C C C +C+ CP + + + CCP+C + Sbjct: 684 GEYFVEGETWNIDSCTQCTCHSGRVLCETEVCPPLLCQNPSRTQDSCCPQCTDQPFRPSL 743 Query: 112 -----VKNFCEY-HGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPE 165 V N+C+ G + E +KP C C C S + C C C PV Sbjct: 744 SRNNSVPNYCKNDEGDIFLAAESWKPDVCTSCICIDS-VISCFSESCPSVSCERPVLRKG 802 Query: 166 QCCPVC------KNGPNCFAGTTIIPAGIEVKVDECNICHCHNGDWWKPAQCSKREC 216 QCCP C K F+G +D C C+C G CS C Sbjct: 803 QCCPYCIEDTIPKKVVCHFSGKAYADEE-RWDLDSCTHCYCLQGQ----TLCSTVSC 854 Score = 55.8 bits (133), Expect = 3e-08 Identities = 44/163 (26%), Positives = 65/163 (39%), Gaps = 26/163 (15%) Query: 73 NCP-CVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKE-VKNF-----CEYHGKNYKI 125 NC C C +C +C +I+ + V CCP C++ V F C +G Sbjct: 353 NCRFCRCQGGVAICFTAQCGEINCERYYVPEGECCPVCEDPVYPFNNPAGCYANGLILAH 412 Query: 126 LEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNG----------- 174 + ++ C +C+C + E HCV C C NPV P +CCPVC+ Sbjct: 413 GDRWREDDCTFCQCV-NGERHCVATVCG-QTCTNPVKVPGECCPVCEEPTIITVDPPACG 470 Query: 175 --PNCFAGTTIIPAGIEVKVDECNICHCHNGDWWKPAQCSKRE 215 NC G + + C C C N + CS+R+ Sbjct: 471 ELSNCTLTGKDCINGFKRDHNGCRTCQCINTE----ELCSERK 509 Score = 54.3 bits (129), Expect = 8e-08 Identities = 43/145 (29%), Positives = 57/145 (39%), Gaps = 31/145 (21%) Query: 85 CDQPECPKIHPKCTKVEHNGCCP-ECKE---------VKNFC----EYHGKNYKILEEFK 130 C + C KI P + + +GC +C+E + C +H KN EE Sbjct: 567 CPELSCSKICPLGFQQDSHGCLICKCREASASAGPPILSGTCLTVDGHHHKN----EESW 622 Query: 131 PSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNG----------PN-CFA 179 C C C E+ C + C VP C NP P QCCP C + P+ C A Sbjct: 623 HDGCRECYCLNGREM-CALITCPVPACGNPTIHPGQCCPSCADDFVVQKPELSTPSICHA 681 Query: 180 -GTTIIPAGIEVKVDECNICHCHNG 203 G G +D C C CH+G Sbjct: 682 PGGEYFVEGETWNIDSCTQCTCHSG 706 Score = 30.4 bits (67), Expect = 1.3 Identities = 34/156 (21%), Positives = 46/156 (29%), Gaps = 37/156 (23%) Query: 82 GPVCDQPECPKIHP------KCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPSPCE 135 G CD EC + +C V+ C P+ +Y+ C Sbjct: 239 GECCDLYECKPVFGVDCRTVECPPVQQTACPPD-------------SYETQVRLTADGC- 284 Query: 136 WCRCEPSNEVHCVVADCAVPECV---------NPVYEPEQCCPV--CKNG--PNCFAGTT 182 C C+ C P C P +CC V C N P C Sbjct: 285 ---CTLPTRCECLSGLCGFPVCEVGSTPRIVSRGDGTPGKCCDVFECVNDTKPACVFNNV 341 Query: 183 IIPAGIEVKVDECNICHCHNG-DWWKPAQCSKRECQ 217 G ++D C C C G AQC + C+ Sbjct: 342 EYYDGDMFRMDNCRFCRCQGGVAICFTAQCGEINCE 377 >gi|37693519 BMP-binding endothelial regulator precursor protein [Homo sapiens] Length = 685 Score = 54.3 bits (129), Expect = 8e-08 Identities = 44/153 (28%), Positives = 54/153 (35%), Gaps = 31/153 (20%) Query: 76 CVCALDGPVCDQPECPKIHPKCTKV--EHNGCCPECKEVKNFCEYHGKNYKILEEFK-PS 132 CVC C + +CP + C + CC +CK C Y G Y FK S Sbjct: 70 CVCLNKEVTCKREKCPVLSRDCALAIKQRGACCEQCKG----CTYEGNTYN--SSFKWQS 123 Query: 133 PCEWCRCEPSNE-------VHCVVADCAVPECVNPVYEPEQCCPVCKNGPNCFAGTTIIP 185 P E C E V CVV C NP+ CCP C P C Sbjct: 124 PAEPCVLRQCQEGVVTESGVRCVV------HCKNPLEHLGMCCPTC---PGCVFEGVQYQ 174 Query: 186 AGIEVKVD--ECNICHCHNGDWWKPAQCSKREC 216 G E + + +C C C G QC + C Sbjct: 175 EGEEFQPEGSKCTKCSCTGG----RTQCVREVC 203 Score = 51.2 bits (121), Expect = 7e-07 Identities = 43/153 (28%), Positives = 57/153 (37%), Gaps = 21/153 (13%) Query: 75 PCVC--ALDGPVCDQPECPKIHPKCTKVEHNG-CCPECKEVKNFCEYHGKNYKILEEFKP 131 PCV +G V + +H K +EH G CCP C C + G Y+ EEF+P Sbjct: 127 PCVLRQCQEGVVTESGVRCVVHCK-NPLEHLGMCCPTCPG----CVFEGVQYQEGEEFQP 181 Query: 132 --SPCEWCRCEPSNEVHCVVADCAVPECVNPVYE--PEQCCPVCKNG--------PNCFA 179 S C C C CV C + C + P QCCP C +C Sbjct: 182 EGSKCTKCSCT-GGRTQCVREVCPILSCPQHLSHIPPGQCCPKCLGQRKVFDLPFGSCLF 240 Query: 180 GTTIIPAGIEVKVDECNICHCHNGDWWKPAQCS 212 + + G D C C C + +CS Sbjct: 241 RSDVYDNGSSFLYDNCTACTCRDSTVVCKRKCS 273 Score = 40.0 bits (92), Expect = 0.002 Identities = 32/126 (25%), Positives = 47/126 (37%), Gaps = 18/126 (14%) Query: 60 VYKLGERFFPGHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPEC-----KEVKN 114 VY G F + NC D V + +C HP GCC EC E Sbjct: 244 VYDNGSSFL--YDNCTACTCRDSTVVCKRKCS--HPGGCDQGQEGCCEECLLRVPPEDIK 299 Query: 115 FCEYHGKNYKILEEFKPSPCEWCRC-----EPSNEVHCVVADCAVPECVNPVYEPEQCCP 169 C++ K ++ E + C C C E N+ ++ C + +N + CCP Sbjct: 300 VCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILN----RKGCCP 355 Query: 170 VCKNGP 175 +C P Sbjct: 356 ICTEKP 361 Score = 30.4 bits (67), Expect = 1.3 Identities = 20/69 (28%), Positives = 24/69 (34%), Gaps = 8/69 (11%) Query: 60 VYKLGERFFPGHS-----NCP-CVCALDGPVCDQPECPKIH--PKCTKVEHNGCCPECKE 111 V K G + F NC C C C +C I P+ + GCCP C E Sbjct: 300 VCKFGNKIFQDGEMWSSINCTICACVKGRTECRNKQCIPISSCPQGKILNRKGCCPICTE 359 Query: 112 VKNFCEYHG 120 C G Sbjct: 360 KPGVCTVFG 368 >gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens] Length = 1499 Score = 50.1 bits (118), Expect = 2e-06 Identities = 22/61 (36%), Positives = 35/61 (57%), Gaps = 2/61 (3%) Query: 116 CEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCA-VPECVNPVYEPEQCCPVCKNG 174 C +G+ Y + +KP+PC+ C C+ + + C +C V +C +PV P +CCPVC Sbjct: 41 CTQNGQMYLNRDIWKPAPCQICVCD-NGAILCDKIECQDVLDCADPVTPPGECCPVCSQT 99 Query: 175 P 175 P Sbjct: 100 P 100 Score = 30.4 bits (67), Expect = 1.3 Identities = 25/103 (24%), Positives = 39/103 (37%), Gaps = 17/103 (16%) Query: 10 ILLLVIPGLVTSAAISHEDYPADEGDQISSNDNLIFDDYRGKGCVDDSGFVYKLGERFFP 69 ++L+V+ G S ED G++I+ N G +Y + + P Sbjct: 12 LILIVLLGQFVSIKAQEEDEDEGYGEEIACTQN---------------GQMYLNRDIWKP 56 Query: 70 GHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNG-CCPECKE 111 CVC +CD+ EC + V G CCP C + Sbjct: 57 APCQI-CVCDNGAILCDKIECQDVLDCADPVTPPGECCPVCSQ 98 >gi|223029476 NEL-like protein 2 isoform d [Homo sapiens] Length = 839 Score = 47.4 bits (111), Expect = 1e-05 Identities = 36/155 (23%), Positives = 58/155 (37%), Gaps = 14/155 (9%) Query: 58 GFVYKLGERFFPGHSNCPCV---CALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKN 114 G Y+ E + G NC C+ + +C P+CP K +G C CKE K+ Sbjct: 301 GTTYREFESWIDGCKNCTCLNGTIQCETLICPNPDCPL---KSALAYVDGKC--CKECKS 355 Query: 115 FCEYHGKNYKILEE----FKPSPCEWCRCEPSNEVHCVVADCAVPEC--VNPVYEPEQCC 168 C++ G+ Y E C C+ + C +C + + CC Sbjct: 356 ICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCC 415 Query: 169 PVCKNGPNCFAGTTIIPAGIEVKVDECNICHCHNG 203 VCK C + I +++ +C C +G Sbjct: 416 KVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDG 450 Score = 47.4 bits (111), Expect = 1e-05 Identities = 56/222 (25%), Positives = 80/222 (36%), Gaps = 45/222 (20%) Query: 17 GLVTSAAISHEDYP-ADEGDQISSNDNLIFD-----DYR---GKGCVDD---SGFVYKLG 64 G+ + + S ED G +ND + F+ D R GK C D G V G Sbjct: 614 GMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDGKVKHNG 673 Query: 65 ERFFPGHSNCP-CVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECK-EVKNFCEY-HGK 121 + + + C C C +C + C +P CCPEC + + C + +G+ Sbjct: 674 QIWVLENDRCSVCSCQNGFVMCRRMVCDCENPTVDLF----CCPECDPRLSSQCLHQNGE 729 Query: 122 NYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGP------ 175 + C+ CRC EV C C EC + +CCP C P Sbjct: 730 TLYNSGDTWVQNCQQCRCL-QGEVDCWPLPCPDVECEFSILPENECCPRCVTDPCQADTI 788 Query: 176 ------NC--------FAGTTIIPAGIEVKVDECNICHCHNG 203 C F G++ I G EC +C C NG Sbjct: 789 RNDITKTCLDEMNVVRFTGSSWIKHG-----TECTLCQCKNG 825 >gi|223029474 NEL-like protein 2 isoform c [Homo sapiens] Length = 815 Score = 47.4 bits (111), Expect = 1e-05 Identities = 36/155 (23%), Positives = 58/155 (37%), Gaps = 14/155 (9%) Query: 58 GFVYKLGERFFPGHSNCPCV---CALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKN 114 G Y+ E + G NC C+ + +C P+CP K +G C CKE K+ Sbjct: 277 GTTYREFESWIDGCKNCTCLNGTIQCETLICPNPDCPL---KSALAYVDGKC--CKECKS 331 Query: 115 FCEYHGKNYKILEE----FKPSPCEWCRCEPSNEVHCVVADCAVPEC--VNPVYEPEQCC 168 C++ G+ Y E C C+ + C +C + + CC Sbjct: 332 ICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCC 391 Query: 169 PVCKNGPNCFAGTTIIPAGIEVKVDECNICHCHNG 203 VCK C + I +++ +C C +G Sbjct: 392 KVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDG 426 Score = 47.4 bits (111), Expect = 1e-05 Identities = 56/222 (25%), Positives = 80/222 (36%), Gaps = 45/222 (20%) Query: 17 GLVTSAAISHEDYP-ADEGDQISSNDNLIFD-----DYR---GKGCVDD---SGFVYKLG 64 G+ + + S ED G +ND + F+ D R GK C D G V G Sbjct: 590 GMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDGKVKHNG 649 Query: 65 ERFFPGHSNCP-CVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECK-EVKNFCEY-HGK 121 + + + C C C +C + C +P CCPEC + + C + +G+ Sbjct: 650 QIWVLENDRCSVCSCQNGFVMCRRMVCDCENPTVDLF----CCPECDPRLSSQCLHQNGE 705 Query: 122 NYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGP------ 175 + C+ CRC EV C C EC + +CCP C P Sbjct: 706 TLYNSGDTWVQNCQQCRCL-QGEVDCWPLPCPDVECEFSILPENECCPRCVTDPCQADTI 764 Query: 176 ------NC--------FAGTTIIPAGIEVKVDECNICHCHNG 203 C F G++ I G EC +C C NG Sbjct: 765 RNDITKTCLDEMNVVRFTGSSWIKHG-----TECTLCQCKNG 801 >gi|223029472 NEL-like protein 2 isoform b precursor [Homo sapiens] Length = 816 Score = 47.4 bits (111), Expect = 1e-05 Identities = 36/155 (23%), Positives = 58/155 (37%), Gaps = 14/155 (9%) Query: 58 GFVYKLGERFFPGHSNCPCV---CALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKN 114 G Y+ E + G NC C+ + +C P+CP K +G C CKE K+ Sbjct: 278 GTTYREFESWIDGCKNCTCLNGTIQCETLICPNPDCPL---KSALAYVDGKC--CKECKS 332 Query: 115 FCEYHGKNYKILEE----FKPSPCEWCRCEPSNEVHCVVADCAVPEC--VNPVYEPEQCC 168 C++ G+ Y E C C+ + C +C + + CC Sbjct: 333 ICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCC 392 Query: 169 PVCKNGPNCFAGTTIIPAGIEVKVDECNICHCHNG 203 VCK C + I +++ +C C +G Sbjct: 393 KVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDG 427 Score = 47.4 bits (111), Expect = 1e-05 Identities = 56/222 (25%), Positives = 80/222 (36%), Gaps = 45/222 (20%) Query: 17 GLVTSAAISHEDYP-ADEGDQISSNDNLIFD-----DYR---GKGCVDD---SGFVYKLG 64 G+ + + S ED G +ND + F+ D R GK C D G V G Sbjct: 591 GMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDGKVKHNG 650 Query: 65 ERFFPGHSNCP-CVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECK-EVKNFCEY-HGK 121 + + + C C C +C + C +P CCPEC + + C + +G+ Sbjct: 651 QIWVLENDRCSVCSCQNGFVMCRRMVCDCENPTVDLF----CCPECDPRLSSQCLHQNGE 706 Query: 122 NYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGP------ 175 + C+ CRC EV C C EC + +CCP C P Sbjct: 707 TLYNSGDTWVQNCQQCRCL-QGEVDCWPLPCPDVECEFSILPENECCPRCVTDPCQADTI 765 Query: 176 ------NC--------FAGTTIIPAGIEVKVDECNICHCHNG 203 C F G++ I G EC +C C NG Sbjct: 766 RNDITKTCLDEMNVVRFTGSSWIKHG-----TECTLCQCKNG 802 >gi|223029470 NEL-like protein 2 isoform a [Homo sapiens] Length = 866 Score = 47.4 bits (111), Expect = 1e-05 Identities = 36/155 (23%), Positives = 58/155 (37%), Gaps = 14/155 (9%) Query: 58 GFVYKLGERFFPGHSNCPCV---CALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKN 114 G Y+ E + G NC C+ + +C P+CP K +G C CKE K+ Sbjct: 328 GTTYREFESWIDGCKNCTCLNGTIQCETLICPNPDCPL---KSALAYVDGKC--CKECKS 382 Query: 115 FCEYHGKNYKILEE----FKPSPCEWCRCEPSNEVHCVVADCAVPEC--VNPVYEPEQCC 168 C++ G+ Y E C C+ + C +C + + CC Sbjct: 383 ICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCC 442 Query: 169 PVCKNGPNCFAGTTIIPAGIEVKVDECNICHCHNG 203 VCK C + I +++ +C C +G Sbjct: 443 KVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDG 477 Score = 47.4 bits (111), Expect = 1e-05 Identities = 56/222 (25%), Positives = 80/222 (36%), Gaps = 45/222 (20%) Query: 17 GLVTSAAISHEDYP-ADEGDQISSNDNLIFD-----DYR---GKGCVDD---SGFVYKLG 64 G+ + + S ED G +ND + F+ D R GK C D G V G Sbjct: 641 GMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDGKVKHNG 700 Query: 65 ERFFPGHSNCP-CVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECK-EVKNFCEY-HGK 121 + + + C C C +C + C +P CCPEC + + C + +G+ Sbjct: 701 QIWVLENDRCSVCSCQNGFVMCRRMVCDCENPTVDLF----CCPECDPRLSSQCLHQNGE 756 Query: 122 NYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGP------ 175 + C+ CRC EV C C EC + +CCP C P Sbjct: 757 TLYNSGDTWVQNCQQCRCL-QGEVDCWPLPCPDVECEFSILPENECCPRCVTDPCQADTI 815 Query: 176 ------NC--------FAGTTIIPAGIEVKVDECNICHCHNG 203 C F G++ I G EC +C C NG Sbjct: 816 RNDITKTCLDEMNVVRFTGSSWIKHG-----TECTLCQCKNG 852 >gi|5453766 NEL-like protein 2 isoform b precursor [Homo sapiens] Length = 816 Score = 47.4 bits (111), Expect = 1e-05 Identities = 36/155 (23%), Positives = 58/155 (37%), Gaps = 14/155 (9%) Query: 58 GFVYKLGERFFPGHSNCPCV---CALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKN 114 G Y+ E + G NC C+ + +C P+CP K +G C CKE K+ Sbjct: 278 GTTYREFESWIDGCKNCTCLNGTIQCETLICPNPDCPL---KSALAYVDGKC--CKECKS 332 Query: 115 FCEYHGKNYKILEE----FKPSPCEWCRCEPSNEVHCVVADCAVPEC--VNPVYEPEQCC 168 C++ G+ Y E C C+ + C +C + + CC Sbjct: 333 ICQFQGRTYFEGERNTVYSSSGVCVLYECKDQTMKLVESSGCPALDCPESHQITLSHSCC 392 Query: 169 PVCKNGPNCFAGTTIIPAGIEVKVDECNICHCHNG 203 VCK C + I +++ +C C +G Sbjct: 393 KVCKGYDFCSERHNCMENSICRNLNDRAVCSCRDG 427 Score = 47.4 bits (111), Expect = 1e-05 Identities = 56/222 (25%), Positives = 80/222 (36%), Gaps = 45/222 (20%) Query: 17 GLVTSAAISHEDYP-ADEGDQISSNDNLIFD-----DYR---GKGCVDD---SGFVYKLG 64 G+ + + S ED G +ND + F+ D R GK C D G V G Sbjct: 591 GMFSPSGESCEDIDECGTGRHSCANDTICFNLDGGYDCRCPHGKNCTGDCIHDGKVKHNG 650 Query: 65 ERFFPGHSNCP-CVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECK-EVKNFCEY-HGK 121 + + + C C C +C + C +P CCPEC + + C + +G+ Sbjct: 651 QIWVLENDRCSVCSCQNGFVMCRRMVCDCENPTVDLF----CCPECDPRLSSQCLHQNGE 706 Query: 122 NYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNGP------ 175 + C+ CRC EV C C EC + +CCP C P Sbjct: 707 TLYNSGDTWVQNCQQCRCL-QGEVDCWPLPCPDVECEFSILPENECCPRCVTDPCQADTI 765 Query: 176 ------NC--------FAGTTIIPAGIEVKVDECNICHCHNG 203 C F G++ I G EC +C C NG Sbjct: 766 RNDITKTCLDEMNVVRFTGSSWIKHG-----TECTLCQCKNG 802 >gi|30089980 chordin [Homo sapiens] Length = 955 Score = 45.1 bits (105), Expect = 5e-05 Identities = 30/108 (27%), Positives = 38/108 (35%), Gaps = 28/108 (25%) Query: 134 CEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKN----------------GPNC 177 C C C+ V C C P C +PV P+QCCPVC G C Sbjct: 726 CSLCTCQ-RRTVICDPVVCPPPSCPHPVQAPDQCCPVCPEKQDVRDLPGLPRSRDPGEGC 784 Query: 178 F---------AGTTIIPAGIEVKVDECNICHCHNGDWWKPAQCSKREC 216 + AGT P + +C +C C G C K +C Sbjct: 785 YFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGT--GEVHCEKVQC 830 Score = 42.4 bits (98), Expect = 3e-04 Identities = 38/143 (26%), Positives = 52/143 (36%), Gaps = 36/143 (25%) Query: 64 GERFFPGH----SNCPC-----VCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKN 114 G R+ P + S C C +C D VC P CP HP + CPE ++V++ Sbjct: 715 GARWAPNYDPLCSLCTCQRRTVIC--DPVVCPPPSCP--HPVQAPDQCCPVCPEKQDVRD 770 Query: 115 F------------CEYHGKN---------YKILEEFKPSPCEWCRCEP-SNEVHCVVADC 152 C + G + ++ F C C C+ + EVHC C Sbjct: 771 LPGLPRSRDPGEGCYFDGDRSWRAAGTRWHPVVPPFGLIKCAVCTCKGGTGEVHCEKVQC 830 Query: 153 AVPECVNPV-YEPEQCCPVCKNG 174 C PV P CC C G Sbjct: 831 PRLACAQPVRVNPTDCCKQCPVG 853 Score = 30.8 bits (68), Expect = 0.96 Identities = 20/75 (26%), Positives = 25/75 (33%), Gaps = 19/75 (25%) Query: 116 CEYHGKNYKILEEFKPS--------PCEWCRCEPSN---------EVHC--VVADCAVPE 156 C + GK Y + E + P C C CE V C + +C P Sbjct: 51 CTFGGKVYALDETWHPDLGEPFGVMRCVLCACEAPQWGRRTRGPGRVSCKNIKPECPTPA 110 Query: 157 CVNPVYEPEQCCPVC 171 C P P CC C Sbjct: 111 CGQPRQLPGHCCQTC 125 >gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens] Length = 1466 Score = 44.7 bits (104), Expect = 6e-05 Identities = 22/66 (33%), Positives = 34/66 (51%), Gaps = 3/66 (4%) Query: 112 VKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHC--VVADCAVPECVNPVYEPEQCCP 169 V+ C + G++Y + +KP PC+ C C+ S V C ++ D +C NP +CC Sbjct: 28 VEGGCSHLGQSYADRDVWKPEPCQICVCD-SGSVLCDDIICDDQELDCPNPEIPFGECCA 86 Query: 170 VCKNGP 175 VC P Sbjct: 87 VCPQPP 92 >gi|221316568 chordin-like 1 isoform 4 precursor [Homo sapiens] Length = 377 Score = 43.9 bits (102), Expect = 1e-04 Identities = 22/75 (29%), Positives = 33/75 (44%), Gaps = 7/75 (9%) Query: 104 GCCPECKEVKNFCEYHGKNYKILEEFKP--SP-----CEWCRCEPSNEVHCVVADCAVPE 156 G + K + +C + K Y++ E + P P C C C + V C C Sbjct: 25 GKTEQVKHSETYCMFQDKKYRVGERWHPYLEPYGLVYCVNCICSENGNVLCSRVRCPNVH 84 Query: 157 CVNPVYEPEQCCPVC 171 C++PV+ P CCP C Sbjct: 85 CLSPVHIPHLCCPRC 99 >gi|169211819 PREDICTED: keratin associated protein [Homo sapiens] Length = 517 Score = 42.4 bits (98), Expect = 3e-04 Identities = 41/143 (28%), Positives = 52/143 (36%), Gaps = 39/143 (27%) Query: 76 CVCALDGPVCDQPECPK---IHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPS 132 C + GP C QP CP P C + C P C V + C+ P Sbjct: 49 CGSSSCGPQCRQPSCPVSSCAQPLC--CDPVICEPSC-SVSSGCQ-------------PV 92 Query: 133 PCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNG----PNCFAGTTIIPAGI 188 CE CEPS C V++C P C +E C P C P CF T P+ Sbjct: 93 CCEATTCEPS----CSVSNCYQPVC----FEATICEPSCSVSNCCQPVCFEATVCEPS-- 142 Query: 189 EVKVDECNICHCHNGDWWKPAQC 211 C++ C +PA C Sbjct: 143 ------CSVSSCAQPVCCEPAIC 159 Score = 38.1 bits (87), Expect = 0.006 Identities = 46/167 (27%), Positives = 59/167 (35%), Gaps = 38/167 (22%) Query: 72 SNCPCVCALDGPVCDQPECPK---IHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEE 128 SNC + VC+ P C P C E C P C V + C+ G + Sbjct: 126 SNCCQPVCFEATVCE-PSCSVSSCAQPVCC--EPAICEPSCS-VSSCCQPVGSEATSCQP 181 Query: 129 F------------KPSPCEWCRCEPSNEVHCVVADCAVPECVNPVY-EPEQCCPVCKNGP 175 K S C+ CEPS C A C +P PV EP C PVC P Sbjct: 182 VLCVPTSCQPVLCKSSCCQPVVCEPS----CCSAVCTLPSSCQPVVCEPSCCQPVCPT-P 236 Query: 176 NCFAGTT-----IIPAGIEVKVDECNICHCHNGDWWKPAQCSKRECQ 217 C ++ P+ E E +IC +PA C C+ Sbjct: 237 TCSVTSSCQAVCCDPSPCEPSCSESSIC--------QPATCVALVCE 275 Score = 36.6 bits (83), Expect = 0.018 Identities = 37/145 (25%), Positives = 52/145 (35%), Gaps = 30/145 (20%) Query: 72 SNCPCVCALDGPVCDQPECPKI---HPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEE 128 + C C++ C QP C + P C+ N C P C E CE + + Sbjct: 97 TTCEPSCSVSN--CYQPVCFEATICEPSCSV--SNCCQPVCFEA-TVCE---PSCSVSSC 148 Query: 129 FKPSPCEWCRCEPSNEVHCVVADCA---------------VPECVNPVYEPEQCCPVCKN 173 +P CE CEPS C V+ C VP PV CC Sbjct: 149 AQPVCCEPAICEPS----CSVSSCCQPVGSEATSCQPVLCVPTSCQPVLCKSSCCQPVVC 204 Query: 174 GPNCFAGTTIIPAGIEVKVDECNIC 198 P+C + +P+ + V E + C Sbjct: 205 EPSCCSAVCTLPSSCQPVVCEPSCC 229 Score = 30.8 bits (68), Expect = 0.96 Identities = 35/137 (25%), Positives = 48/137 (35%), Gaps = 35/137 (25%) Query: 72 SNC-PCVCALDGPVCDQPECP----KIHPKCTKV--EHNGCCPECKEVKNFCEYHGKNYK 124 S+C P VC P C QP CP + C V + + C P C E + C+ Sbjct: 217 SSCQPVVCE---PSCCQPVCPTPTCSVTSSCQAVCCDPSPCEPSCSE-SSICQPATCVAL 272 Query: 125 ILEE--FKPSPCEWCRCEPSN------EVHCVVADCAVPECVNP---------------- 160 + E +P C CEP + E C V+ P C P Sbjct: 273 VCEPVCLRPVCCVQSSCEPPSVPSTCQEPSCCVSSICQPICSEPSPCSPAVCVSSPCQPT 332 Query: 161 VYEPEQCCPVCKNGPNC 177 Y ++C VC +C Sbjct: 333 CYVVKRCPSVCPEPVSC 349 >gi|239745811 PREDICTED: hypothetical protein XP_002343557 [Homo sapiens] Length = 517 Score = 42.4 bits (98), Expect = 3e-04 Identities = 41/143 (28%), Positives = 52/143 (36%), Gaps = 39/143 (27%) Query: 76 CVCALDGPVCDQPECPK---IHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPS 132 C + GP C QP CP P C + C P C V + C+ P Sbjct: 49 CGSSSCGPQCRQPSCPVSSCAQPLC--CDPVICEPSC-SVSSGCQ-------------PV 92 Query: 133 PCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNG----PNCFAGTTIIPAGI 188 CE CEPS C V++C P C +E C P C P CF T P+ Sbjct: 93 CCEATTCEPS----CSVSNCYQPVC----FEATICEPSCSVSNCCQPVCFEATVCEPS-- 142 Query: 189 EVKVDECNICHCHNGDWWKPAQC 211 C++ C +PA C Sbjct: 143 ------CSVSSCAQPVCCEPAIC 159 Score = 38.1 bits (87), Expect = 0.006 Identities = 46/167 (27%), Positives = 59/167 (35%), Gaps = 38/167 (22%) Query: 72 SNCPCVCALDGPVCDQPECPK---IHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEE 128 SNC + VC+ P C P C E C P C V + C+ G + Sbjct: 126 SNCCQPVCFEATVCE-PSCSVSSCAQPVCC--EPAICEPSCS-VSSCCQPVGSEATSCQP 181 Query: 129 F------------KPSPCEWCRCEPSNEVHCVVADCAVPECVNPVY-EPEQCCPVCKNGP 175 K S C+ CEPS C A C +P PV EP C PVC P Sbjct: 182 VLCVPTSCQPVLCKSSCCQPVVCEPS----CCSAVCTLPSSCQPVVCEPSCCQPVCPT-P 236 Query: 176 NCFAGTT-----IIPAGIEVKVDECNICHCHNGDWWKPAQCSKRECQ 217 C ++ P+ E E +IC +PA C C+ Sbjct: 237 TCSVTSSCQAVCCDPSPCEPSCSESSIC--------QPATCVALVCE 275 Score = 36.6 bits (83), Expect = 0.018 Identities = 37/145 (25%), Positives = 52/145 (35%), Gaps = 30/145 (20%) Query: 72 SNCPCVCALDGPVCDQPECPKI---HPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEE 128 + C C++ C QP C + P C+ N C P C E CE + + Sbjct: 97 TTCEPSCSVSN--CYQPVCFEATICEPSCSV--SNCCQPVCFEA-TVCE---PSCSVSSC 148 Query: 129 FKPSPCEWCRCEPSNEVHCVVADCA---------------VPECVNPVYEPEQCCPVCKN 173 +P CE CEPS C V+ C VP PV CC Sbjct: 149 AQPVCCEPAICEPS----CSVSSCCQPVGSEATSCQPVLCVPTSCQPVLCKSSCCQPVVC 204 Query: 174 GPNCFAGTTIIPAGIEVKVDECNIC 198 P+C + +P+ + V E + C Sbjct: 205 EPSCCSAVCTLPSSCQPVVCEPSCC 229 Score = 30.8 bits (68), Expect = 0.96 Identities = 35/137 (25%), Positives = 48/137 (35%), Gaps = 35/137 (25%) Query: 72 SNC-PCVCALDGPVCDQPECP----KIHPKCTKV--EHNGCCPECKEVKNFCEYHGKNYK 124 S+C P VC P C QP CP + C V + + C P C E + C+ Sbjct: 217 SSCQPVVCE---PSCCQPVCPTPTCSVTSSCQAVCCDPSPCEPSCSE-SSICQPATCVAL 272 Query: 125 ILEE--FKPSPCEWCRCEPSN------EVHCVVADCAVPECVNP---------------- 160 + E +P C CEP + E C V+ P C P Sbjct: 273 VCEPVCLRPVCCVQSSCEPPSVPSTCQEPSCCVSSICQPICSEPSPCSPAVCVSSPCQPT 332 Query: 161 VYEPEQCCPVCKNGPNC 177 Y ++C VC +C Sbjct: 333 CYVVKRCPSVCPEPVSC 349 >gi|169212026 PREDICTED: keratin associated protein [Homo sapiens] Length = 517 Score = 42.0 bits (97), Expect = 4e-04 Identities = 41/143 (28%), Positives = 52/143 (36%), Gaps = 39/143 (27%) Query: 76 CVCALDGPVCDQPECPK---IHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPS 132 C + GP C QP CP P C + C P C V + C+ P Sbjct: 49 CGSSSCGPQCRQPSCPVSSCAQPLC--CDPVICEPSC-SVSSGCQ-------------PV 92 Query: 133 PCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQCCPVCKNG----PNCFAGTTIIPAGI 188 CE CEPS C V++C P C +E C P C P CF T P+ Sbjct: 93 CCEATTCEPS----CSVSNCYQPVC----FEATICEPSCSVSNCCQPVCFEATICEPS-- 142 Query: 189 EVKVDECNICHCHNGDWWKPAQC 211 C++ C +PA C Sbjct: 143 ------CSVSSCAQPVCCEPAIC 159 Score = 37.4 bits (85), Expect = 0.010 Identities = 45/167 (26%), Positives = 59/167 (35%), Gaps = 38/167 (22%) Query: 72 SNCPCVCALDGPVCDQPECPK---IHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEE 128 SNC + +C+ P C P C E C P C V + C+ G + Sbjct: 126 SNCCQPVCFEATICE-PSCSVSSCAQPVCC--EPAICEPSCS-VSSCCQPVGSEATSCQP 181 Query: 129 F------------KPSPCEWCRCEPSNEVHCVVADCAVPECVNPVY-EPEQCCPVCKNGP 175 K S C+ CEPS C A C +P PV EP C PVC P Sbjct: 182 VLCVPTSCQPVLCKSSCCQPVVCEPS----CCSAVCTLPSSCQPVVCEPSCCQPVCPT-P 236 Query: 176 NCFAGTT-----IIPAGIEVKVDECNICHCHNGDWWKPAQCSKRECQ 217 C ++ P+ E E +IC +PA C C+ Sbjct: 237 TCSVTSSCQAVCCDPSPCEPTCSESSIC--------QPATCVALVCE 275 Score = 37.0 bits (84), Expect = 0.013 Identities = 37/145 (25%), Positives = 52/145 (35%), Gaps = 30/145 (20%) Query: 72 SNCPCVCALDGPVCDQPECPKI---HPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEE 128 + C C++ C QP C + P C+ N C P C E CE + + Sbjct: 97 TTCEPSCSVSN--CYQPVCFEATICEPSCSV--SNCCQPVCFEA-TICE---PSCSVSSC 148 Query: 129 FKPSPCEWCRCEPSNEVHCVVADCA---------------VPECVNPVYEPEQCCPVCKN 173 +P CE CEPS C V+ C VP PV CC Sbjct: 149 AQPVCCEPAICEPS----CSVSSCCQPVGSEATSCQPVLCVPTSCQPVLCKSSCCQPVVC 204 Query: 174 GPNCFAGTTIIPAGIEVKVDECNIC 198 P+C + +P+ + V E + C Sbjct: 205 EPSCCSAVCTLPSSCQPVVCEPSCC 229 Score = 30.4 bits (67), Expect = 1.3 Identities = 35/137 (25%), Positives = 48/137 (35%), Gaps = 35/137 (25%) Query: 72 SNC-PCVCALDGPVCDQPECP----KIHPKCTKV--EHNGCCPECKEVKNFCEYHGKNYK 124 S+C P VC P C QP CP + C V + + C P C E + C+ Sbjct: 217 SSCQPVVCE---PSCCQPVCPTPTCSVTSSCQAVCCDPSPCEPTCSE-SSICQPATCVAL 272 Query: 125 ILEE--FKPSPCEWCRCEPSN------EVHCVVADCAVPECVNP---------------- 160 + E +P C CEP + E C V+ P C P Sbjct: 273 VCEPVCLRPVCCVQSSCEPPSVPSTCQEPSCCVSSICQPICSEPSPCSPAVCVSSPCQPT 332 Query: 161 VYEPEQCCPVCKNGPNC 177 Y ++C VC +C Sbjct: 333 CYVVKRCRSVCPEPVSC 349 >gi|239755778 PREDICTED: mucin 19, oligomeric [Homo sapiens] Length = 598 Score = 41.6 bits (96), Expect = 5e-04 Identities = 42/149 (28%), Positives = 60/149 (40%), Gaps = 22/149 (14%) Query: 63 LGERFFPGH---SNCPCVCALDGPV--CDQPECP-----KIHPKCTKVEHNGCCPECKEV 112 LGE PG +NC D C ECP K K K + N C E Sbjct: 379 LGEEKSPGDIWTANCHRGTCTDAKTIDCKPEECPSPPTCKTGEKLVKFQSNDTCCEIGYC 438 Query: 113 K-NFCEYHGKNYKILEEFKP--SPCEWCRCEPSNEVHCVVADCAVPEC---VNPVYEPEQ 166 + C ++ +Y+I F +PC C+ + VV DC N +Y+ ++ Sbjct: 439 EPRTCLFNNTDYEIGASFDDPSNPCVSYSCKDTGFA-AVVQDCPKQTWCAEANRIYDSKK 497 Query: 167 CCPVCKNGPNC---FAGTTIIPAGIEVKV 192 CC CKN NC T+I +G + +V Sbjct: 498 CCYTCKN--NCRSSLVNVTVIYSGCKKRV 524 >gi|239750280 PREDICTED: mucin 19, oligomeric [Homo sapiens] Length = 598 Score = 41.6 bits (96), Expect = 5e-04 Identities = 42/149 (28%), Positives = 60/149 (40%), Gaps = 22/149 (14%) Query: 63 LGERFFPGH---SNCPCVCALDGPV--CDQPECP-----KIHPKCTKVEHNGCCPECKEV 112 LGE PG +NC D C ECP K K K + N C E Sbjct: 379 LGEEKSPGDIWTANCHRGTCTDAKTIDCKPEECPSPPTCKTGEKLVKFQSNDTCCEIGYC 438 Query: 113 K-NFCEYHGKNYKILEEFKP--SPCEWCRCEPSNEVHCVVADCAVPEC---VNPVYEPEQ 166 + C ++ +Y+I F +PC C+ + VV DC N +Y+ ++ Sbjct: 439 EPRTCLFNNTDYEIGASFDDPSNPCVSYSCKDTGFA-AVVQDCPKQTWCAEANRIYDSKK 497 Query: 167 CCPVCKNGPNC---FAGTTIIPAGIEVKV 192 CC CKN NC T+I +G + +V Sbjct: 498 CCYTCKN--NCRSSLVNVTVIYSGCKKRV 524 >gi|239744589 PREDICTED: mucin 19 [Homo sapiens] Length = 598 Score = 41.6 bits (96), Expect = 5e-04 Identities = 42/149 (28%), Positives = 60/149 (40%), Gaps = 22/149 (14%) Query: 63 LGERFFPGH---SNCPCVCALDGPV--CDQPECP-----KIHPKCTKVEHNGCCPECKEV 112 LGE PG +NC D C ECP K K K + N C E Sbjct: 379 LGEEKSPGDIWTANCHRGTCTDAKTIDCKPEECPSPPTCKTGEKLVKFQSNDTCCEIGYC 438 Query: 113 K-NFCEYHGKNYKILEEFKP--SPCEWCRCEPSNEVHCVVADCAVPEC---VNPVYEPEQ 166 + C ++ +Y+I F +PC C+ + VV DC N +Y+ ++ Sbjct: 439 EPRTCLFNNTDYEIGASFDDPSNPCVSYSCKDTGFA-AVVQDCPKQTWCAEANRIYDSKK 497 Query: 167 CCPVCKNGPNC---FAGTTIIPAGIEVKV 192 CC CKN NC T+I +G + +V Sbjct: 498 CCYTCKN--NCRSSLVNVTVIYSGCKKRV 524 >gi|148833508 notch1 preproprotein [Homo sapiens] Length = 2555 Score = 40.8 bits (94), Expect = 0.001 Identities = 51/191 (26%), Positives = 68/191 (35%), Gaps = 63/191 (32%) Query: 70 GHSNCPCVCALDGPVCDQP--ECPKIHPKCTKVEHNGCCP------ECKEVKNFCEYHGK 121 G + C C GP C Q EC C EH G C EC+ ++ Y G Sbjct: 394 GKAICTCPSGYTGPACSQDVDECSLGANPC---EHAGKCINTLGSFECQCLQG---YTGP 447 Query: 122 NYKI-LEEFKPSPCE------------WCRCEPSNE-VHCVVA--DCAVPECVNP----- 160 +I + E +PC+ C C P E VHC V +CA C++ Sbjct: 448 RCEIDVNECVSNPCQNDATCLDQIGEFQCICMPGYEGVHCEVNTDECASSPCLHNGRCLD 507 Query: 161 ------------------VYEPEQCCPV-CKNGPNCFAG----TTIIPAGI-----EVKV 192 Y+ ++C CKNG C G T + G EV + Sbjct: 508 KINEFQCECPTGFTGHLCQYDVDECASTPCKNGAKCLDGPNTYTCVCTEGYTGTHCEVDI 567 Query: 193 DECNICHCHNG 203 DEC+ CH G Sbjct: 568 DECDPDPCHYG 578 Score = 28.5 bits (62), Expect = 4.8 Identities = 30/122 (24%), Positives = 43/122 (35%), Gaps = 23/122 (18%) Query: 70 GHSNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCE----YHGKNYKI 125 G C C GP C++P P C ++ G C +V + C + G+N + Sbjct: 200 GSYRCVCRATHTGPNCERPYVPCSPSPC---QNGGTCRPTGDVTHECACLPGFTGQNCE- 255 Query: 126 LEEFKPSPCEWCRCEPSNEVHCV----VADCAVPE------CVNPVYEPEQCCPVCKNGP 175 E P C+ N CV +C P C V E + C+NG Sbjct: 256 -ENIDDCPGNNCK----NGGACVDGVNTYNCRCPPEWTGQYCTEDVDECQLMPNACQNGG 310 Query: 176 NC 177 C Sbjct: 311 TC 312 Score = 28.1 bits (61), Expect = 6.2 Identities = 31/132 (23%), Positives = 47/132 (35%), Gaps = 29/132 (21%) Query: 74 CPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPSP 133 C C+ G C+ P C NG EC++ ++Y+ P+ Sbjct: 815 CNCLLPYTGATCEVVLAPCAPSPC----RNG--GECRQ--------SEDYESFSCVCPTG 860 Query: 134 CEWCRCEPS-NEVHCVVADCAVPECVNPVYEPEQC-CPVCKNGPNCFAGTTIIPAGIEVK 191 + CE NE CV++ C + +C C +G NC E Sbjct: 861 WQGQTCEVDINE--CVLSPCRHGASCQNTHGGYRCHCQAGYSGRNC-----------ETD 907 Query: 192 VDECNICHCHNG 203 +D+C CHNG Sbjct: 908 IDDCRPNPCHNG 919 >gi|109150416 peroxidasin [Homo sapiens] Length = 1479 Score = 40.8 bits (94), Expect = 0.001 Identities = 25/73 (34%), Positives = 30/73 (41%), Gaps = 7/73 (9%) Query: 99 KVEHNGCCPECKEVKNFCEYHGKNYKILEEFKPSPCEWCRCEPSNEVHCVVADCAVPECV 158 K+E EC + E H N K +K C C C+ +V C V C C Sbjct: 1405 KLESRLSTTECVDAGG--ESHANNTK----WKKDACTICECK-DGQVTCFVEACPPATCA 1457 Query: 159 NPVYEPEQCCPVC 171 PV P CCPVC Sbjct: 1458 VPVNIPGACCPVC 1470 >gi|148727298 keratin associated protein 10-6 [Homo sapiens] Length = 365 Score = 40.8 bits (94), Expect = 0.001 Identities = 39/161 (24%), Positives = 54/161 (33%), Gaps = 13/161 (8%) Query: 72 SNCPCVCALDGPVCDQPECPKIHPKCTKVEHNGCCPECKEVKNFCEYHGKNYKILEEFKP 131 ++ PC A PVC +P C I C + C + CE P Sbjct: 147 TSSPCQQACCVPVCCKPVCSGISSSCCQQSSCVSCVSSPCCQAVCEPSPCQSGCTSSCTP 206 Query: 132 SPCEWCRCEPS------NEVHCVVADCAVPECVNPV--YEPEQCCPVCKNGPNCFAGTTI 183 S C+ C+P+ + C V C VP C P + CC P C T Sbjct: 207 SCCQQSSCQPTCCTSSPCQQACCVPVCCVPVCCVPTCSEDSSSCCQQSSCQPAC---CTS 263 Query: 184 IPAGIEVKVDECN--ICHCHNGDWWKPAQCSKRECQGKQTV 222 P V C+ C +PA C+ C+ +V Sbjct: 264 SPCQHACCVPVCSGASTSCCQQSSCQPACCTASCCRPSSSV 304 Score = 35.8 bits (81), Expect = 0.030 Identities = 37/155 (23%), Positives = 45/155 (29%), Gaps = 23/155 (14%) Query: 74 CPCVCALDGPVCDQPECPKIHPKCTKVE-HNGCC------PECKEVKNFCEYHGKNYKIL 126 C VC D C Q C CT CC P C + + C + Sbjct: 125 CVSVCCGDSSCCQQSSCQS--ACCTSSPCQQACCVPVCCKPVCSGISSSCCQQSSCVSCV 182 Query: 127 EEFKPSPCEWCRCEPSNEVHCVVADCAVPECVNPVYEPEQC----CPVCKNGPNCFAGTT 182 SPC CEPS + C C +P C C P C Sbjct: 183 S----SPCCQAVCEPSPCQSGCTSSCTPSCCQQSSCQPTCCTSSPCQQACCVPVCCVPVC 238 Query: 183 IIPAGIEVKVDECNICHCHNGDWWKPAQCSKRECQ 217 +P E C C +PA C+ CQ Sbjct: 239 CVPTCSEDSSSCCQQSSC------QPACCTSSPCQ 267 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.322 0.141 0.501 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 11,200,032 Number of Sequences: 37866 Number of extensions: 615555 Number of successful extensions: 2833 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 55 Number of HSP's successfully gapped in prelim test: 192 Number of HSP's that attempted gapping in prelim test: 2002 Number of HSP's gapped (non-prelim): 694 length of query: 222 length of database: 18,247,518 effective HSP length: 98 effective length of query: 124 effective length of database: 14,536,650 effective search space: 1802544600 effective search space used: 1802544600 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.9 bits) S2: 60 (27.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.