Search of human proteins with 32698940

Search of human proteins with 32698940

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|32698940 transmembrane protease, serine 12 [Homo sapiens]
         (348 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|32698940 transmembrane protease, serine 12 [Homo sapiens]          726   0.0  
gi|223942069 enterokinase precursor [Homo sapiens]                    185   5e-47
gi|148613878 acrosin precursor [Homo sapiens]                         184   8e-47
gi|4758508 transmembrane protease, serine 11D [Homo sapiens]          184   1e-46
gi|33667063 transmembrane protease, serine 9 [Homo sapiens]           177   1e-44
gi|4505881 plasminogen [Homo sapiens]                                 177   2e-44
gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo sa...   176   2e-44
gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo sa...   176   2e-44
gi|33695155 hepsin [Homo sapiens]                                     176   4e-44
gi|4504481 hepsin [Homo sapiens]                                      176   4e-44
gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]             174   8e-44
gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo sa...   168   6e-42
gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo sap...   168   6e-42
gi|187761337 transmembrane protease, serine 11B [Homo sapiens]        166   2e-41
gi|23957702 transmembrane protease, serine 6 [Homo sapiens]           166   2e-41
gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo sap...   166   3e-41
gi|11415040 matriptase [Homo sapiens]                                 166   4e-41
gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]          164   1e-40
gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo ...   164   1e-40
gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo ...   164   1e-40
gi|205360905 testis-specific serine protease 1 [Homo sapiens]         163   2e-40
gi|4506153 prostasin preproprotein [Homo sapiens]                     162   3e-40
gi|116256363 transmembrane protease, serine 13 [Homo sapiens]         162   3e-40
gi|13994276 marapsin [Homo sapiens]                                   161   7e-40
gi|29244926 corin [Homo sapiens]                                      159   4e-39
gi|194018492 transmembrane protease, serine 11F [Homo sapiens]        159   4e-39
gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]               157   1e-38
gi|170932492 transmembrane protease, serine 5 [Homo sapiens]          157   1e-38
gi|110815798 ovochymase 1 [Homo sapiens]                              157   1e-38
gi|40254871 transmembrane protease, serine 11E [Homo sapiens]         156   2e-38

>gi|32698940 transmembrane protease, serine 12 [Homo sapiens]
          Length = 348

 Score =  726 bits (1874), Expect = 0.0
 Identities = 348/348 (100%), Positives = 348/348 (100%)

Query: 1   MRLGLLSVALLFVGSSHLYSDHYSPSGRHRLGPSPEPAASSQQAEAVRKRLRRRREGGAH 60
           MRLGLLSVALLFVGSSHLYSDHYSPSGRHRLGPSPEPAASSQQAEAVRKRLRRRREGGAH
Sbjct: 1   MRLGLLSVALLFVGSSHLYSDHYSPSGRHRLGPSPEPAASSQQAEAVRKRLRRRREGGAH 60

Query: 61  AKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTA 120
           AKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTA
Sbjct: 61  AKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTA 120

Query: 121 AHCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKA 180
           AHCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKA
Sbjct: 121 AHCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKA 180

Query: 181 VRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSE 240
           VRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSE
Sbjct: 181 VRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSE 240

Query: 241 RSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFP 300
           RSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFP
Sbjct: 241 RSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFP 300

Query: 301 GVYIGPSFYQKWLTEHFFHASTQGILTINILRGQILIALCFVILLATT 348
           GVYIGPSFYQKWLTEHFFHASTQGILTINILRGQILIALCFVILLATT
Sbjct: 301 GVYIGPSFYQKWLTEHFFHASTQGILTINILRGQILIALCFVILLATT 348


>gi|223942069 enterokinase precursor [Homo sapiens]
          Length = 1019

 Score =  185 bits (470), Expect = 5e-47
 Identities = 102/245 (41%), Positives = 143/245 (58%), Gaps = 11/245 (4%)

Query: 77   RIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDAS-DPLMWTA 135
            +I+GG+ A+ GAWPWVV L    GR+L   CG +LV   W+++AAHC    + +P  WTA
Sbjct: 784  KIVGGSNAKEGAWPWVVGLYYG-GRLL---CGASLVSSDWLVSAAHCVYGRNLEPSKWTA 839

Query: 136  VIGTN-NIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPF 194
            ++G +   +   P T    I  I+I+P++      NDIA+ HL+  V Y DYIQPICLP 
Sbjct: 840  ILGLHMKSNLTSPQTVPRLIDEIVINPHYNRRRKDNDIAMMHLEFKVNYTDYIQPICLP- 898

Query: 195  DVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCA 254
            +  Q+      C I+GWG    +G   NILQ+A+V  +S E C  +     I  N   CA
Sbjct: 899  EENQVFPPGRNCSIAGWGTVVYQGTTANILQEADVPLLSNERCQQQMPEYNITEN-MICA 957

Query: 255  GDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLT 314
            G E+G  D+C+GDSGGPLMC   E  R+F+ G+TS+G+ C     PGVY   S + +W+ 
Sbjct: 958  GYEEGGIDSCQGDSGGPLMC--QENNRWFLAGVTSFGYKCALPNRPGVYARVSRFTEWI- 1014

Query: 315  EHFFH 319
            + F H
Sbjct: 1015 QSFLH 1019


>gi|148613878 acrosin precursor [Homo sapiens]
          Length = 421

 Score =  184 bits (468), Expect = 8e-47
 Identities = 102/259 (39%), Positives = 141/259 (54%), Gaps = 11/259 (4%)

Query: 64  CGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQI-KYGRVLVHVCGGTLVRERWVLTAAH 122
           CG    ++   G RI+GG  AQ GAWPW+VSLQI  Y     H CGG+L+  RWVLTAAH
Sbjct: 29  CGLRFRQNPQGGVRIVGGKAAQHGAWPWMVSLQIFTYNSHRYHTCGGSLLNSRWVLTAAH 88

Query: 123 CTKDASDPLMWTAVIGTNNIHGRYPHTKKIK-------IKAIIIHPNFILESYVNDIALF 175
           C    ++   W  V G   I   Y + K +K       ++ IIIH  +   +  NDIAL 
Sbjct: 89  CFVGKNNVHDWRLVFGAKEI--TYGNNKPVKAPLQERYVEKIIIHEKYNSATEGNDIALV 146

Query: 176 HLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEG-NATNILQDAEVHYISR 234
            +   +    +I P CLP     +  G+  C+++GWG  +E+    ++IL +A V  I  
Sbjct: 147 EITPPISCGRFIGPGCLPHFKAGLPRGSQSCWVAGWGYIEEKAPRPSSILMEARVDLIDL 206

Query: 235 EMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGC 294
           ++CNS + Y G +  T+ CAG   G  DTC+GDSGGPLMC   +   + V+GITS+G GC
Sbjct: 207 DLCNSTQWYNGRVQPTNVCAGYPVGKIDTCQGDSGGPLMCKDSKESAYVVVGITSWGVGC 266

Query: 295 GRRGFPGVYIGPSFYQKWL 313
            R   PG+Y     Y  W+
Sbjct: 267 ARAKRPGIYTATWPYLNWI 285


>gi|4758508 transmembrane protease, serine 11D [Homo sapiens]
          Length = 418

 Score =  184 bits (467), Expect = 1e-46
 Identities = 103/290 (35%), Positives = 154/290 (53%), Gaps = 21/290 (7%)

Query: 26  SGRHRLGPSPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTAPLKDVLQGSRIIGGTEAQ 85
           SG   + PS E  + + QA A                +CG  P    L   RI+GGTEA+
Sbjct: 146 SGNLEINPSTEITSLTDQAAA-----------NWLINECGAGPDLITLSEQRILGGTEAE 194

Query: 86  AGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLMWTAVIGTNNIHGR 145
            G+WPW VSL++       H CGG+L+   W+LTAAHC +  S+P  W   I T+ I   
Sbjct: 195 EGSWPWQVSLRLNNA----HHCGGSLINNMWILTAAHCFRSNSNPRDW---IATSGISTT 247

Query: 146 YPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTK 205
           +P  + ++++ I+IH N+   ++ NDIAL  L+ +V +   I  +CLP     I  G+T 
Sbjct: 248 FPKLR-MRVRNILIHNNYKSATHENDIALVRLENSVTFTKDIHSVCLPAATQNIPPGST- 305

Query: 206 CFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCR 265
            +++GWG  +  G+    L+  +V  IS ++CN+  SY G I +   CAG   G  D C+
Sbjct: 306 AYVTGWGAQEYAGHTVPELRQGQVRIISNDVCNAPHSYNGAILSGMLCAGVPQGGVDACQ 365

Query: 266 GDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTE 315
           GDSGGPL+      + +F++GI S+G  CG    PGVY   + Y  W+ +
Sbjct: 366 GDSGGPLV-QEDSRRLWFIVGIVSWGDQCGLPDKPGVYTRVTAYLDWIRQ 414


>gi|33667063 transmembrane protease, serine 9 [Homo sapiens]
          Length = 1059

 Score =  177 bits (449), Expect = 1e-44
 Identities = 101/254 (39%), Positives = 138/254 (54%), Gaps = 13/254 (5%)

Query: 63   DCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAH 122
            DCG AP       +RI+GG+ A  G WPW VSL ++      H CG  LV ERW+L+AAH
Sbjct: 816  DCGLAPAAL----TRIVGGSAAGRGEWPWQVSLWLRRRE---HRCGAVLVAERWLLSAAH 868

Query: 123  CTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVR 182
            C     DP  W A +GT  + G     +  ++  I  HP + L +   D+AL  L   VR
Sbjct: 869  CFDVYGDPKQWAAFLGTPFLSGAEGQLE--RVARIYKHPFYNLYTLDYDVALLELAGPVR 926

Query: 183  YNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERS 242
             +  ++PICLP    +  DG T+C I+GWG  +E G+    LQ A V  +S + C   R 
Sbjct: 927  RSRLVRPICLPEPAPRPPDG-TRCVITGWGSVREGGSMARQLQKAAVRLLSEQTC--RRF 983

Query: 243  YGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGV 302
            Y   I +   CAG   G  D+C GD+GGPL C  P   R+ + G+TS+G+GCGR  FPGV
Sbjct: 984  YPVQISSRMLCAGFPQGGVDSCSGDAGGPLACREPS-GRWVLTGVTSWGYGCGRPHFPGV 1042

Query: 303  YIGPSFYQKWLTEH 316
            Y   +  + W+ +H
Sbjct: 1043 YTRVAAVRGWIGQH 1056



 Score =  166 bits (419), Expect = 4e-41
 Identities = 93/260 (35%), Positives = 135/260 (51%), Gaps = 11/260 (4%)

Query: 63  DCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAH 122
           +CG  P   +    RI+GG EA  G +PW  SL+        H CG  ++  RW+++AAH
Sbjct: 190 ECGLQPAWRM--AGRIVGGMEASPGEFPWQASLRENKE----HFCGAAIINARWLVSAAH 243

Query: 123 CTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVR 182
           C  +  DP  W A +G   + G    T + ++  I+ HP +  ++   D+A+  L   + 
Sbjct: 244 CFNEFQDPTKWVAYVGATYLSGSEASTVRAQVVQIVKHPLYNADTADFDVAVLELTSPLP 303

Query: 183 YNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNA-TNILQDAEVHYISREMCNSER 241
           +  +IQP+CLP     I   + KC ISGWG  KE+      +LQ A V  + + +C S  
Sbjct: 304 FGRHIQPVCLP-AATHIFPPSKKCLISGWGYLKEDFLVKPEVLQKATVELLDQALCAS-- 360

Query: 242 SYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPG 301
            YG  + +   CAG  DG  D+C+GDSGGPL+C  P   RFF+ GI S+G GC     PG
Sbjct: 361 LYGHSLTDRMVCAGYLDGKVDSCQGDSGGPLVCEEPS-GRFFLAGIVSWGIGCAEARRPG 419

Query: 302 VYIGPSFYQKWLTEHFFHAS 321
           VY   +  + W+ E    AS
Sbjct: 420 VYARVTRLRDWILEATTKAS 439



 Score =  148 bits (374), Expect = 6e-36
 Identities = 94/256 (36%), Positives = 140/256 (54%), Gaps = 14/256 (5%)

Query: 62  KDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAA 121
           ++CG  P  +  + +R++GG  A +G  PW VSL  K G    H CG T+V +RW+L+AA
Sbjct: 490 QECGARPAME--KPTRVVGGFGAASGEVPWQVSL--KEGSR--HFCGATVVGDRWLLSAA 543

Query: 122 HCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAV 181
           HC        +  A +GT ++ G      KI ++ +++HP +       D+A+  L   +
Sbjct: 544 HCFNHTKVEQV-RAHLGTASLLGLGGSPVKIGLRRVVLHPLYNPGILDFDLAVLELASPL 602

Query: 182 RYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATN--ILQDAEVHYISREMCNS 239
            +N YIQP+CLP  + +   G  KC ISGWG T +EGNAT   +LQ A V  I ++ C+ 
Sbjct: 603 AFNKYIQPVCLPLAIQKFPVGR-KCMISGWGNT-QEGNATKPELLQKASVGIIDQKTCSV 660

Query: 240 ERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGF 299
              Y   + +   CAG  +G  D+C+GDSGGPL C       F++ GI S+G GC +   
Sbjct: 661 --LYNFSLTDRMICAGFLEGKVDSCQGDSGGPLACE-EAPGVFYLAGIVSWGIGCAQVKK 717

Query: 300 PGVYIGPSFYQKWLTE 315
           PGVY   +  + W+ E
Sbjct: 718 PGVYTRITRLKGWILE 733


>gi|4505881 plasminogen [Homo sapiens]
          Length = 810

 Score =  177 bits (448), Expect = 2e-44
 Identities = 89/251 (35%), Positives = 138/251 (54%), Gaps = 13/251 (5%)

Query: 63  DCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAH 122
           DCG   ++      R++GG  A   +WPW VSL+ ++G   +H CGGTL+   WVLTAAH
Sbjct: 566 DCGKPQVEPKKCPGRVVGGCVAHPHSWPWQVSLRTRFG---MHFCGGTLISPEWVLTAAH 622

Query: 123 CTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVR 182
           C + +  P  +  ++G +      PH ++I++  + + P         DIAL  L     
Sbjct: 623 CLEKSPRPSSYKVILGAHQEVNLEPHVQEIEVSRLFLEPT------RKDIALLKLSSPAV 676

Query: 183 YNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERS 242
             D + P CLP   + + D  T+CFI+GWG T+    A  +L++A++  I  ++CN    
Sbjct: 677 ITDKVIPACLPSPNYVVAD-RTECFITGWGETQGTFGA-GLLKEAQLPVIENKVCNRYEF 734

Query: 243 YGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGV 302
             G + +T  CAG   G  D+C+GDSGGPL+C+  E  ++ + G+TS+G GC R   PGV
Sbjct: 735 LNGRVQSTELCAGHLAGGTDSCQGDSGGPLVCF--EKDKYILQGVTSWGLGCARPNKPGV 792

Query: 303 YIGPSFYQKWL 313
           Y+  S +  W+
Sbjct: 793 YVRVSRFVTWI 803


>gi|227499990 transmembrane protease, serine 2 isoform 1 [Homo
           sapiens]
          Length = 529

 Score =  176 bits (447), Expect = 2e-44
 Identities = 92/239 (38%), Positives = 139/239 (58%), Gaps = 9/239 (3%)

Query: 76  SRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCT-KDASDPLMWT 134
           SRI+GG  A  GAWPW VSL ++     VHVCGG+++   W++TAAHC  K  ++P  WT
Sbjct: 291 SRIVGGESALPGAWPWQVSLHVQN----VHVCGGSIITPEWIVTAAHCVEKPLNNPWHWT 346

Query: 135 AVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPF 194
           A  G       + +    +++ +I HPN+  ++  NDIAL  L+K + +ND ++P+CLP 
Sbjct: 347 AFAGILRQSFMF-YGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLP- 404

Query: 195 DVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCA 254
           +   +L     C+ISGWG T+E+G  + +L  A+V  I  + CNS   Y  +I     CA
Sbjct: 405 NPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICA 464

Query: 255 GDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWL 313
           G   G  D+C+GDSGGPL+    +   ++++G TS+G GC +   PGVY     +  W+
Sbjct: 465 GFLQGNVDSCQGDSGGPLV--TSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 521


>gi|205360943 transmembrane protease, serine 2 isoform 2 [Homo
           sapiens]
          Length = 492

 Score =  176 bits (447), Expect = 2e-44
 Identities = 92/239 (38%), Positives = 139/239 (58%), Gaps = 9/239 (3%)

Query: 76  SRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCT-KDASDPLMWT 134
           SRI+GG  A  GAWPW VSL ++     VHVCGG+++   W++TAAHC  K  ++P  WT
Sbjct: 254 SRIVGGESALPGAWPWQVSLHVQN----VHVCGGSIITPEWIVTAAHCVEKPLNNPWHWT 309

Query: 135 AVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPF 194
           A  G       + +    +++ +I HPN+  ++  NDIAL  L+K + +ND ++P+CLP 
Sbjct: 310 AFAGILRQSFMF-YGAGYQVEKVISHPNYDSKTKNNDIALMKLQKPLTFNDLVKPVCLP- 367

Query: 195 DVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCA 254
           +   +L     C+ISGWG T+E+G  + +L  A+V  I  + CNS   Y  +I     CA
Sbjct: 368 NPGMMLQPEQLCWISGWGATEEKGKTSEVLNAAKVLLIETQRCNSRYVYDNLITPAMICA 427

Query: 255 GDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWL 313
           G   G  D+C+GDSGGPL+    +   ++++G TS+G GC +   PGVY     +  W+
Sbjct: 428 GFLQGNVDSCQGDSGGPLV--TSKNNIWWLIGDTSWGSGCAKAYRPGVYGNVMVFTDWI 484


>gi|33695155 hepsin [Homo sapiens]
          Length = 417

 Score =  176 bits (445), Expect = 4e-44
 Identities = 102/285 (35%), Positives = 148/285 (51%), Gaps = 21/285 (7%)

Query: 53  RRREGGAHAKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLV 112
           R R   A  +DCG    +  L   RI+GG +   G WPW VSL+        H+CGG+L+
Sbjct: 142 RGRFLAAICQDCG----RRKLPVDRIVGGRDTSLGRWPWQVSLRYDGA----HLCGGSLL 193

Query: 113 RERWVLTAAHCTKDASDPLM-WTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFI------L 165
              WVLTAAHC  + +  L  W    G   +    PH  ++ ++A++ H  ++       
Sbjct: 194 SGDWVLTAAHCFPERNRVLSRWRVFAGA--VAQASPHGLQLGVQAVVYHGGYLPFRDPNS 251

Query: 166 ESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQ 225
           E   NDIAL HL   +   +YIQP+CLP     ++DG   C ++GWG T+  G    +LQ
Sbjct: 252 EENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKI-CTVTGWGNTQYYGQQAGVLQ 310

Query: 226 DAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMC--YLPEYKRFF 283
           +A V  IS ++CN    YG  I    FCAG  +G  D C+GDSGGP +C   +    R+ 
Sbjct: 311 EARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWR 370

Query: 284 VMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHF-FHASTQGILT 327
           + GI S+G GC     PGVY   S +++W+ +    H+   G++T
Sbjct: 371 LCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGMVT 415


>gi|4504481 hepsin [Homo sapiens]
          Length = 417

 Score =  176 bits (445), Expect = 4e-44
 Identities = 102/285 (35%), Positives = 148/285 (51%), Gaps = 21/285 (7%)

Query: 53  RRREGGAHAKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLV 112
           R R   A  +DCG    +  L   RI+GG +   G WPW VSL+        H+CGG+L+
Sbjct: 142 RGRFLAAICQDCG----RRKLPVDRIVGGRDTSLGRWPWQVSLRYDGA----HLCGGSLL 193

Query: 113 RERWVLTAAHCTKDASDPLM-WTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFI------L 165
              WVLTAAHC  + +  L  W    G   +    PH  ++ ++A++ H  ++       
Sbjct: 194 SGDWVLTAAHCFPERNRVLSRWRVFAGA--VAQASPHGLQLGVQAVVYHGGYLPFRDPNS 251

Query: 166 ESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQ 225
           E   NDIAL HL   +   +YIQP+CLP     ++DG   C ++GWG T+  G    +LQ
Sbjct: 252 EENSNDIALVHLSSPLPLTEYIQPVCLPAAGQALVDGKI-CTVTGWGNTQYYGQQAGVLQ 310

Query: 226 DAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMC--YLPEYKRFF 283
           +A V  IS ++CN    YG  I    FCAG  +G  D C+GDSGGP +C   +    R+ 
Sbjct: 311 EARVPIISNDVCNGADFYGNQIKPKMFCAGYPEGGIDACQGDSGGPFVCEDSISRTPRWR 370

Query: 284 VMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHF-FHASTQGILT 327
           + GI S+G GC     PGVY   S +++W+ +    H+   G++T
Sbjct: 371 LCGIVSWGTGCALAQKPGVYTKVSDFREWIFQAIKTHSEASGMVT 415


>gi|78191798 plasma kallikrein B1 precursor [Homo sapiens]
          Length = 638

 Score =  174 bits (442), Expect = 8e-44
 Identities = 97/242 (40%), Positives = 135/242 (55%), Gaps = 9/242 (3%)

Query: 76  SRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLMWTA 135
           +RI+GGT +  G WPW VSLQ+K      H+CGG+L+  +WVLTAAHC        +W  
Sbjct: 389 TRIVGGTNSSWGEWPWQVSLQVKL-TAQRHLCGGSLIGHQWVLTAAHCFDGLPLQDVWRI 447

Query: 136 VIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPF- 194
             G  N+      T   +IK IIIH N+ +    +DIAL  L+  + Y ++ +PICLP  
Sbjct: 448 YSGILNLSDITKDTPFSQIKEIIIHQNYKVSEGNHDIALIKLQAPLNYTEFQKPICLPSK 507

Query: 195 -DVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFC 253
            D   I    T C+++GWG +KE+G   NILQ   +  ++ E C  +R     I     C
Sbjct: 508 GDTSTIY---TNCWVTGWGFSKEKGEIQNILQKVNIPLVTNEEC-QKRYQDYKITQRMVC 563

Query: 254 AGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWL 313
           AG ++G  D C+GDSGGPL+C       + ++GITS+G GC RR  PGVY   + Y  W+
Sbjct: 564 AGYKEGGKDACKGDSGGPLVC--KHNGMWRLVGITSWGEGCARREQPGVYTKVAEYMDWI 621

Query: 314 TE 315
            E
Sbjct: 622 LE 623


>gi|145701030 transmembrane protease, serine 4 isoform 3 [Homo
           sapiens]
          Length = 432

 Score =  168 bits (426), Expect = 6e-42
 Identities = 98/255 (38%), Positives = 141/255 (55%), Gaps = 18/255 (7%)

Query: 60  HAKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLT 119
           H   CG +     L+  R++GG EA   +WPW VS+Q  Y +   HVCGG+++   WVLT
Sbjct: 187 HCLACGKS-----LKTPRVVGGEEASVDSWPWQVSIQ--YDKQ--HVCGGSILDPHWVLT 237

Query: 120 AAHCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKK 179
           AAHC +  +D   W    G++ + G +P     KI  I  +P +  +   NDIAL  L+ 
Sbjct: 238 AAHCFRKHTDVFNWKVRAGSDKL-GSFPSLAVAKIIIIEFNPMYPKD---NDIALMKLQF 293

Query: 180 AVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNA-TNILQDAEVHYISREMCN 238
            + ++  ++PICLPF   + L   T  +I GWG TK+ G   ++IL  A V  I    CN
Sbjct: 294 PLTFSGTVRPICLPF-FDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCN 352

Query: 239 SERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRG 298
           ++ +Y G +     CAG  +G  DTC+GDSGGPLM    +  ++ V+GI S+G+GCG   
Sbjct: 353 ADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMY---QSDQWHVVGIVSWGYGCGGPS 409

Query: 299 FPGVYIGPSFYQKWL 313
            PGVY   S Y  W+
Sbjct: 410 TPGVYTKVSAYLNWI 424


>gi|15451940 transmembrane protease, serine 4 isoform 1 [Homo
           sapiens]
          Length = 437

 Score =  168 bits (426), Expect = 6e-42
 Identities = 98/255 (38%), Positives = 141/255 (55%), Gaps = 18/255 (7%)

Query: 60  HAKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLT 119
           H   CG +     L+  R++GG EA   +WPW VS+Q  Y +   HVCGG+++   WVLT
Sbjct: 192 HCLACGKS-----LKTPRVVGGEEASVDSWPWQVSIQ--YDKQ--HVCGGSILDPHWVLT 242

Query: 120 AAHCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKK 179
           AAHC +  +D   W    G++ + G +P     KI  I  +P +  +   NDIAL  L+ 
Sbjct: 243 AAHCFRKHTDVFNWKVRAGSDKL-GSFPSLAVAKIIIIEFNPMYPKD---NDIALMKLQF 298

Query: 180 AVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNA-TNILQDAEVHYISREMCN 238
            + ++  ++PICLPF   + L   T  +I GWG TK+ G   ++IL  A V  I    CN
Sbjct: 299 PLTFSGTVRPICLPF-FDEELTPATPLWIIGWGFTKQNGGKMSDILLQASVQVIDSTRCN 357

Query: 239 SERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRG 298
           ++ +Y G +     CAG  +G  DTC+GDSGGPLM    +  ++ V+GI S+G+GCG   
Sbjct: 358 ADDAYQGEVTEKMMCAGIPEGGVDTCQGDSGGPLMY---QSDQWHVVGIVSWGYGCGGPS 414

Query: 299 FPGVYIGPSFYQKWL 313
            PGVY   S Y  W+
Sbjct: 415 TPGVYTKVSAYLNWI 429


>gi|187761337 transmembrane protease, serine 11B [Homo sapiens]
          Length = 416

 Score =  166 bits (421), Expect = 2e-41
 Identities = 90/251 (35%), Positives = 135/251 (53%), Gaps = 10/251 (3%)

Query: 64  CGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHC 123
           CG      ++ G++I+ G  +  GAWPW  S+Q K GR   H CG +L+  RW+L+AAHC
Sbjct: 171 CGRQVANSIITGNKIVNGKSSLEGAWPWQASMQWK-GR---HYCGASLISSRWLLSAAHC 226

Query: 124 TKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRY 183
               ++   WT   G   I    P+  + K++ II H N+      +DIAL  L + V +
Sbjct: 227 FAKKNNSKDWTVNFG---IVVNKPYMTR-KVQNIIFHENYSSPGLHDDIALVQLAEEVSF 282

Query: 184 NDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSY 243
            +YI+ ICLP +    L  N    ++GWG     G+   ILQ+  +  I  ++CN+  +Y
Sbjct: 283 TEYIRKICLP-EAKMKLSENDNVVVTGWGTLYMNGSFPVILQEDFLKIIDNKICNASYAY 341

Query: 244 GGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVY 303
            G + +T  CAG   G  D C+ DSGGPL  Y      + ++GI S+G GCG++  PGVY
Sbjct: 342 SGFVTDTMLCAGFMSGEADACQNDSGGPL-AYPDSRNIWHLVGIVSWGDGCGKKNKPGVY 400

Query: 304 IGPSFYQKWLT 314
              + Y+ W+T
Sbjct: 401 TRVTSYRNWIT 411


>gi|23957702 transmembrane protease, serine 6 [Homo sapiens]
          Length = 811

 Score =  166 bits (421), Expect = 2e-41
 Identities = 93/257 (36%), Positives = 140/257 (54%), Gaps = 19/257 (7%)

Query: 63  DCGTAPLKDVLQG--SRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTA 120
           DCG       LQG  SRI+GG  +  G WPW  SLQ++ GR   H+CGG L+ +RWV+TA
Sbjct: 567 DCG-------LQGPSSRIVGGAVSSEGEWPWQASLQVR-GR---HICGGALIADRWVITA 615

Query: 121 AHCTKDAS--DPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLK 178
           AHC ++ S    ++WT  +G    + R+P     K+  +++HP    +S+  D+AL  L 
Sbjct: 616 AHCFQEDSMASTVLWTVFLGKVWQNSRWPGEVSFKVSRLLLHPYHEEDSHDYDVALLQLD 675

Query: 179 KAVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCN 238
             V  +  ++P+CLP       +    C+I+GWG  +E G  +N LQ  +V  I +++C+
Sbjct: 676 HPVVRSAAVRPVCLPAR-SHFFEPGLHCWITGWGALREGGPISNALQKVDVQLIPQDLCS 734

Query: 239 SERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRG 298
               Y   +     CAG   G  D C+GDSGGPL+C      R+F+ G+ S+G GCGR  
Sbjct: 735 EVYRYQ--VTPRMLCAGYRKGKKDACQGDSGGPLVCKALS-GRWFLAGLVSWGLGCGRPN 791

Query: 299 FPGVYIGPSFYQKWLTE 315
           + GVY   +    W+ +
Sbjct: 792 YFGVYTRITGVISWIQQ 808


>gi|13173471 transmembrane protease, serine 3 isoform 1 [Homo
           sapiens]
          Length = 454

 Score =  166 bits (420), Expect = 3e-41
 Identities = 91/241 (37%), Positives = 133/241 (55%), Gaps = 10/241 (4%)

Query: 76  SRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLMWTA 135
           SRI+GG  +    WPW  SLQ +      H+CGG+++   W++TAAHC  D   P  WT 
Sbjct: 215 SRIVGGNMSLLSQWPWQASLQFQG----YHLCGGSVITPLWIITAAHCVYDLYLPKSWTI 270

Query: 136 VIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFD 195
            +G  ++    P    + ++ I+ H  +  +   NDIAL  L   + +N+ IQP+CLP  
Sbjct: 271 QVGLVSLLDN-PAPSHL-VEKIVYHSKYKPKRLGNDIALMKLAGPLTFNEMIQPVCLPNS 328

Query: 196 VFQILDGNTKCFISGWGRTKE-EGNATNILQDAEVHYISREMCNSERSYGGIIPNTSFCA 254
                DG   C+ SGWG T++  G+A+ +L  A V  IS ++CN    YGGII  +  CA
Sbjct: 329 EENFPDGKV-CWTSGWGATEDGAGDASPVLNHAAVPLISNKICNHRDVYGGIISPSMLCA 387

Query: 255 GDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWLT 314
           G   G  D+C+GDSGGPL+C   E + + ++G TS+G GC     PGVY   + +  W+ 
Sbjct: 388 GYLTGGVDSCQGDSGGPLVC--QERRLWKLVGATSFGIGCAEVNKPGVYTRVTSFLDWIH 445

Query: 315 E 315
           E
Sbjct: 446 E 446


>gi|11415040 matriptase [Homo sapiens]
          Length = 855

 Score =  166 bits (419), Expect = 4e-41
 Identities = 95/266 (35%), Positives = 140/266 (52%), Gaps = 16/266 (6%)

Query: 58  GAHAKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQ-IKYGRVLVHVCGGTLVRERW 116
           G+  KDC    L+   + +R++GGT+A  G WPW VSL  +  G    H+CG +L+   W
Sbjct: 596 GSDEKDCDCG-LRSFTRQARVVGGTDADEGEWPWQVSLHALGQG----HICGASLISPNW 650

Query: 117 VLTAAHCTKDA-----SDPLMWTAVIGTNNIHGRY-PHTKKIKIKAIIIHPNFILESYVN 170
           +++AAHC  D      SDP  WTA +G ++   R  P  ++ ++K II HP F   ++  
Sbjct: 651 LVSAAHCYIDDRGFRYSDPTQWTAFLGLHDQSQRSAPGVQERRLKRIISHPFFNDFTFDY 710

Query: 171 DIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVH 230
           DIAL  L+K   Y+  ++PICLP D   +       +++GWG T+  G    ILQ  E+ 
Sbjct: 711 DIALLELEKPAEYSSMVRPICLP-DASHVFPAGKAIWVTGWGHTQYGGTGALILQKGEIR 769

Query: 231 YISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSY 290
            I++  C  E      I     C G   G  D+C+GDSGGPL     +  R F  G+ S+
Sbjct: 770 VINQTTC--ENLLPQQITPRMMCVGFLSGGVDSCQGDSGGPLSSVEAD-GRIFQAGVVSW 826

Query: 291 GHGCGRRGFPGVYIGPSFYQKWLTEH 316
           G GC +R  PGVY     ++ W+ E+
Sbjct: 827 GDGCAQRNKPGVYTRLPLFRDWIKEN 852


>gi|239753545 PREDICTED: similar to hCG2041452 [Homo sapiens]
          Length = 410

 Score =  164 bits (414), Expect = 1e-40
 Identities = 97/253 (38%), Positives = 138/253 (54%), Gaps = 19/253 (7%)

Query: 76  SRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLMWTA 135
           SR+IGG  A    WPW VSLQ       +H CGG+L+  RWVLTAAHC         W  
Sbjct: 161 SRMIGGLPAPNKKWPWQVSLQTSN----IHHCGGSLIDRRWVLTAAHCVFRGCG---WEG 213

Query: 136 VIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFD 195
                   GR+    K  ++ II   NF   +  +DIAL  L  +V Y+ +IQP CLP  
Sbjct: 214 GRWLLAGIGRWDQAWK-HLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEK 272

Query: 196 VFQILDGNTKCFISGWGRTKEE--GNATNILQDAEVHYISREMC-----NSERSYGGIIP 248
           +F++ +  T+C+++GWG+  E   G    +LQ+ E++ +  E C     N   S   ++ 
Sbjct: 273 LFEV-EAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVT 331

Query: 249 NTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSF 308
             + C  ++ G  D C+GDSGGPL+C L     +  +GI S+G GCGR+G+PGVY   SF
Sbjct: 332 RGTVCGYNDQGK-DACQGDSGGPLVCELNG--TWVQVGIVSWGIGCGRKGYPGVYTEVSF 388

Query: 309 YQKWLTEHFFHAS 321
           Y+KW+ +H   AS
Sbjct: 389 YKKWIIDHLRQAS 401


>gi|239748117 PREDICTED: hypothetical protein XP_002346556 [Homo
           sapiens]
          Length = 410

 Score =  164 bits (414), Expect = 1e-40
 Identities = 97/253 (38%), Positives = 138/253 (54%), Gaps = 19/253 (7%)

Query: 76  SRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLMWTA 135
           SR+IGG  A    WPW VSLQ       +H CGG+L+  RWVLTAAHC         W  
Sbjct: 161 SRMIGGLPAPNKKWPWQVSLQTSN----IHHCGGSLIDRRWVLTAAHCVFRGCG---WEG 213

Query: 136 VIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFD 195
                   GR+    K  ++ II   NF   +  +DIAL  L  +V Y+ +IQP CLP  
Sbjct: 214 GRWLLAGIGRWDQAWK-HLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEK 272

Query: 196 VFQILDGNTKCFISGWGRTKEE--GNATNILQDAEVHYISREMC-----NSERSYGGIIP 248
           +F++ +  T+C+++GWG+  E   G    +LQ+ E++ +  E C     N   S   ++ 
Sbjct: 273 LFEV-EAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVT 331

Query: 249 NTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSF 308
             + C  ++ G  D C+GDSGGPL+C L     +  +GI S+G GCGR+G+PGVY   SF
Sbjct: 332 RGTVCGYNDQGK-DACQGDSGGPLVCELNG--TWVQVGIVSWGIGCGRKGYPGVYTEVSF 388

Query: 309 YQKWLTEHFFHAS 321
           Y+KW+ +H   AS
Sbjct: 389 YKKWIIDHLRQAS 401


>gi|239742016 PREDICTED: hypothetical protein XP_002342392 [Homo
           sapiens]
          Length = 410

 Score =  164 bits (414), Expect = 1e-40
 Identities = 97/253 (38%), Positives = 138/253 (54%), Gaps = 19/253 (7%)

Query: 76  SRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLMWTA 135
           SR+IGG  A    WPW VSLQ       +H CGG+L+  RWVLTAAHC         W  
Sbjct: 161 SRMIGGLPAPNKKWPWQVSLQTSN----IHHCGGSLIDRRWVLTAAHCVFRGCG---WEG 213

Query: 136 VIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFD 195
                   GR+    K  ++ II   NF   +  +DIAL  L  +V Y+ +IQP CLP  
Sbjct: 214 GRWLLAGIGRWDQAWK-HLEDIIFPSNFDFATLTSDIALALLAYSVNYSSHIQPACLPEK 272

Query: 196 VFQILDGNTKCFISGWGRTKEE--GNATNILQDAEVHYISREMC-----NSERSYGGIIP 248
           +F++ +  T+C+++GWG+  E   G    +LQ+ E++ +  E C     N   S   ++ 
Sbjct: 273 LFEV-EAGTECWVTGWGQVSESVSGPMPLVLQETELNIMRHEKCCEMLKNKNISKSKMVT 331

Query: 249 NTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSF 308
             + C  ++ G  D C+GDSGGPL+C L     +  +GI S+G GCGR+G+PGVY   SF
Sbjct: 332 RGTVCGYNDQGK-DACQGDSGGPLVCELNG--TWVQVGIVSWGIGCGRKGYPGVYTEVSF 388

Query: 309 YQKWLTEHFFHAS 321
           Y+KW+ +H   AS
Sbjct: 389 YKKWIIDHLRQAS 401


>gi|205360905 testis-specific serine protease 1 [Homo sapiens]
          Length = 318

 Score =  163 bits (412), Expect = 2e-40
 Identities = 97/279 (34%), Positives = 145/279 (51%), Gaps = 23/279 (8%)

Query: 53  RRREGGAHAKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLV 112
           RR  GG   + CG   +  +     + GG E+  G WPW  SL+++      H CGG+L+
Sbjct: 35  RRPGGGGREEACGHREIHAL-----VAGGVESARGRWPWQASLRLRRR----HRCGGSLL 85

Query: 113 RERWVLTAAHCTKDASDPLMWTAVIGTNNIH----GRYPHTKKIKIKAIIIHPNFILESY 168
             RWVL+AAHC +    P  WT  +G             ++ + K++ II++P+  L   
Sbjct: 86  SRRWVLSAAHCFQKHYYPSEWTVQLGELTSRPTPWNLRAYSSRYKVQDIIVNPD-ALGVL 144

Query: 169 VNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNI---LQ 225
            NDIAL  L  +V YN YIQPIC+    F  +     C+++GWG     G        L+
Sbjct: 145 RNDIALLRLASSVTYNAYIQPICIESSTFNFVH-RPDCWVTGWGLISPSGTPLPPPYNLR 203

Query: 226 DAEVHYISREMCN---SERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRF 282
           +A+V  ++   CN    + S   +I ++ FCAG EDG+ DTC+GDSGGPL+C   +   +
Sbjct: 204 EAQVTILNNTRCNYLFEQPSSRSMIWDSMFCAGAEDGSVDTCKGDSGGPLVC--DKDGLW 261

Query: 283 FVMGITSYGHGCGRRGFPGVYIGPSFYQKWLTEHFFHAS 321
           + +GI S+G  CG+   PGVY   S Y  W+     H++
Sbjct: 262 YQVGIVSWGMDCGQPNRPGVYTNISVYFHWIRRVMSHST 300


>gi|4506153 prostasin preproprotein [Homo sapiens]
          Length = 343

 Score =  162 bits (411), Expect = 3e-40
 Identities = 99/264 (37%), Positives = 133/264 (50%), Gaps = 22/264 (8%)

Query: 58  GAHAKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWV 117
           GA A  CG AP       +RI GG+ A AG WPW VS+  +     VHVCGG+LV E+WV
Sbjct: 32  GAEAP-CGVAPQ------ARITGGSSAVAGQWPWQVSITYEG----VHVCGGSLVSEQWV 80

Query: 118 LTAAHCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHL 177
           L+AAHC         +   +G + +       K   +K II HP+++ E    DIAL  L
Sbjct: 81  LSAAHCFPSEHHKEAYEVKLGAHQLDSYSEDAKVSTLKDIIPHPSYLQEGSQGDIALLQL 140

Query: 178 KKAVRYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGN--ATNILQDAEVHYISRE 235
            + + ++ YI+PICLP       +G   C ++GWG      +      LQ  EV  ISRE
Sbjct: 141 SRPITFSRYIRPICLPAANASFPNG-LHCTVTGWGHVAPSVSLLTPKPLQQLEVPLISRE 199

Query: 236 MCN------SERSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITS 289
            CN      ++      +     CAG  +G  D C+GDSGGPL C  P    +++ GI S
Sbjct: 200 TCNCLYNIDAKPEEPHFVQEDMVCAGYVEGGKDACQGDSGGPLSC--PVEGLWYLTGIVS 257

Query: 290 YGHGCGRRGFPGVYIGPSFYQKWL 313
           +G  CG R  PGVY   S Y  W+
Sbjct: 258 WGDACGARNRPGVYTLASSYASWI 281


>gi|116256363 transmembrane protease, serine 13 [Homo sapiens]
          Length = 567

 Score =  162 bits (411), Expect = 3e-40
 Identities = 97/253 (38%), Positives = 137/253 (54%), Gaps = 18/253 (7%)

Query: 77  RIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLM--WT 134
           RI+GG  A    WPW VSL         H+CGGTL+  +WVLTAAHC     + ++  W 
Sbjct: 325 RIVGGALASDSKWPWQVSLHFG----TTHICGGTLIDAQWVLTAAHCFFVTREKVLEGWK 380

Query: 135 AVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPF 194
              GT+N+H + P    I    III+ N+  E    DIAL  L K +  + +I P CLP 
Sbjct: 381 VYAGTSNLH-QLPEAASIA--EIIINSNYTDEEDDYDIALMRLSKPLTLSAHIHPACLPM 437

Query: 195 DVFQILDGNTKCFISGWGRTKEEGNATN-ILQDAEVHYISREMCNSERSYGGIIPNTSFC 253
              Q    N  C+I+G+G+T+E  + T+  L++ +V+ I  + CN    Y   +     C
Sbjct: 438 HG-QTFSLNETCWITGFGKTRETDDKTSPFLREVQVNLIDFKKCNDYLVYDSYLTPRMMC 496

Query: 254 AGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVY-----IGPSF 308
           AGD  G  D+C+GDSGGPL+C   +  R+++ G+TS+G GCG+R  PGVY     + P  
Sbjct: 497 AGDLRGGRDSCQGDSGGPLVC--EQNNRWYLAGVTSWGTGCGQRNKPGVYTKVTEVLPWI 554

Query: 309 YQKWLTEHFFHAS 321
           Y K  +E  F  S
Sbjct: 555 YSKMESEVRFRKS 567


>gi|13994276 marapsin [Homo sapiens]
          Length = 290

 Score =  161 bits (408), Expect = 7e-40
 Identities = 87/247 (35%), Positives = 133/247 (53%), Gaps = 16/247 (6%)

Query: 76  SRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLMWTA 135
           +R++GG + Q G WPW VS+Q    R   H CGG+L+ E+WVLTAAHC ++ S+  ++  
Sbjct: 33  NRMVGGQDTQEGEWPWQVSIQ----RNGSHFCGGSLIAEQWVLTAAHCFRNTSETSLYQV 88

Query: 136 VIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFD 195
           ++G   +    PH    +++ +  +P +   +   D+AL  L+  V + +YI P+CLP D
Sbjct: 89  LLGARQLVQPGPHAMYARVRQVESNPLYQGTASSADVALVELEAPVPFTNYILPVCLP-D 147

Query: 196 VFQILDGNTKCFISGWGRTKEEG--NATNILQDAEVHYISREMCN----SERSYG---GI 246
              I +    C+++GWG   EE       ILQ   V  I    CN     +  +G     
Sbjct: 148 PSVIFETGMNCWVTGWGSPSEEDLLPEPRILQKLAVPIIDTPKCNLLYSKDTEFGYQPKT 207

Query: 247 IPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGP 306
           I N   CAG E+G  D C+GDSGGPL+C + +   +   G+ S+G GC R+  PGVYI  
Sbjct: 208 IKNDMLCAGFEEGKKDACKGDSGGPLVCLVGQ--SWLQAGVISWGEGCARQNRPGVYIRV 265

Query: 307 SFYQKWL 313
           + +  W+
Sbjct: 266 TAHHNWI 272


>gi|29244926 corin [Homo sapiens]
          Length = 1042

 Score =  159 bits (402), Expect = 4e-39
 Identities = 92/259 (35%), Positives = 136/259 (52%), Gaps = 13/259 (5%)

Query: 62   KDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAA 121
            +DCG  P   +    RI+GG  ++ G WPW  SLQ +      H+CG  L+ ++WVLT A
Sbjct: 788  QDCGRRPAARM--NKRILGGRTSRPGRWPWQCSLQSEPSG---HICGCVLIAKKWVLTVA 842

Query: 122  HCTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAV 181
            HC +   +  +W  V+G NN+       +   +K II+HP +       DI++  L + +
Sbjct: 843  HCFEGRENAAVWKVVLGINNLDHPSVFMQTRFVKTIILHPRYSRAVVDYDISIVELSEDI 902

Query: 182  RYNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNI-LQDAEVHYISREMCNSE 240
                Y++P+CLP +  Q L+ +T C+I+GWG     GN     LQ+ EV  IS E C S 
Sbjct: 903  SETGYVRPVCLP-NPEQWLEPDTYCYITGWGHM---GNKMPFKLQEGEVRIISLEHCQSY 958

Query: 241  RSYGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGF- 299
                  I     CAG E G  D+C GDSGGPL+C  P   R+ + G+TS+G  C  +   
Sbjct: 959  FDM-KTITTRMICAGYESGTVDSCMGDSGGPLVCEKPG-GRWTLFGLTSWGSVCFSKVLG 1016

Query: 300  PGVYIGPSFYQKWLTEHFF 318
            PGVY   S++ +W+    +
Sbjct: 1017 PGVYSNVSYFVEWIKRQIY 1035


>gi|194018492 transmembrane protease, serine 11F [Homo sapiens]
          Length = 438

 Score =  159 bits (402), Expect = 4e-39
 Identities = 89/247 (36%), Positives = 127/247 (51%), Gaps = 11/247 (4%)

Query: 68  PLKDVLQGSRIIGGTE-AQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKD 126
           PL       RI+ G E A  G WPW  SLQ+       H CG +L+   W+LTAAHC   
Sbjct: 196 PLPASSSTQRIVQGRETAMEGEWPWQASLQLIGSG---HQCGASLISNTWLLTAAHCFWK 252

Query: 127 ASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDY 186
             DP  W A  G        P   K  ++ II+H N+  E+  NDIAL  L   V +++ 
Sbjct: 253 NKDPTQWIATFGATIT----PPAVKRNVRKIILHENYHRETNENDIALVQLSTGVEFSNI 308

Query: 187 IQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGI 246
           +Q +CLP    + L   T  F++G+G   ++G   N L+ A V  IS ++CN +  Y G+
Sbjct: 309 VQRVCLPDSSIK-LPPKTSVFVTGFGSIVDDGPIQNTLRQARVETISTDVCNRKDVYDGL 367

Query: 247 IPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGP 306
           I     CAG  +G  D C+GDSGGPL+     +  ++++GI S+G  C     PGVY   
Sbjct: 368 ITPGMLCAGFMEGKIDACKGDSGGPLV--YDNHDIWYIVGIVSWGQSCALPKKPGVYTRV 425

Query: 307 SFYQKWL 313
           + Y+ W+
Sbjct: 426 TKYRDWI 432


>gi|116292750 lipoprotein Lp(a) precursor [Homo sapiens]
          Length = 2040

 Score =  157 bits (398), Expect = 1e-38
 Identities = 85/251 (33%), Positives = 131/251 (52%), Gaps = 22/251 (8%)

Query: 63   DCGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAH 122
            DCG   ++       I+GG  A   +WPW VSL+ ++G+   H CGGTL+   WVLTAAH
Sbjct: 1805 DCGKPQVEPKKCPGSIVGGCVAHPHSWPWQVSLRTRFGK---HFCGGTLISPEWVLTAAH 1861

Query: 123  CTKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVR 182
            C K +S P  +  ++G +       H ++I++  + + P         DIAL  L +   
Sbjct: 1862 CLKKSSRPSSYKVILGAHQEVNLESHVQEIEVSRLFLEPT------QADIALLKLSRPAV 1915

Query: 183  YNDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERS 242
              D + P CLP   + +    T+C+I+GWG T +    T +L++A++  I  E+CN  + 
Sbjct: 1916 ITDKVMPACLPSPDYMV-TARTECYITGWGET-QGTFGTGLLKEAQLLVIENEVCNHYK- 1972

Query: 243  YGGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGV 302
                      CA       D+C+GDSGGPL+C+  E  ++ + G+TS+G GC R   PGV
Sbjct: 1973 --------YICAEHLARGTDSCQGDSGGPLVCF--EKDKYILQGVTSWGLGCARPNKPGV 2022

Query: 303  YIGPSFYQKWL 313
            Y   S +  W+
Sbjct: 2023 YARVSRFVTWI 2033


>gi|170932492 transmembrane protease, serine 5 [Homo sapiens]
          Length = 457

 Score =  157 bits (398), Expect = 1e-38
 Identities = 90/283 (31%), Positives = 140/283 (49%), Gaps = 16/283 (5%)

Query: 34  SPEPAASSQQAEAVRKRLRRRREGGAHAKDCGTAPLKDVLQGSRIIGGTEAQAGAWPWVV 93
           SP      ++A   R      +       +CG  PL      SRI+GG     G WPW  
Sbjct: 179 SPRLGGFLEEAWQPRNNCTSGQVVSLRCSECGARPL-----ASRIVGGQSVAPGRWPWQA 233

Query: 94  SLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLM--WTAVIGTNNIHGRYPHTKK 151
           S+ + +     H CGG+++  RWV+TAAHC        +  W    G  +     PH   
Sbjct: 234 SVALGFR----HTCGGSVLAPRWVVTAAHCMHSFRLARLSSWRVHAGLVSHSAVRPHQGA 289

Query: 152 IKIKAIIIHPNFILESYVNDIALFHLKKAVRYNDYIQPICLPFDVFQILDGNTKCFISGW 211
           + ++ II HP +  +++  D+AL  L+ A+ ++D +  +CLP        G+ +C++SGW
Sbjct: 290 L-VERIIPHPLYSAQNHDYDVALLRLQTALNFSDTVGAVCLPAKEQHFPKGS-RCWVSGW 347

Query: 212 GRTKEEGN-ATNILQDAEVHYISREMCNSERSYGGIIPNTSFCAGDEDGAFDTCRGDSGG 270
           G T      ++++LQD  V   S ++CNS   Y G +     CAG  DG  D C+GDSGG
Sbjct: 348 GHTHPSHTYSSDMLQDTVVPLFSTQLCNSSCVYSGALTPRMLCAGYLDGRADACQGDSGG 407

Query: 271 PLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVYIGPSFYQKWL 313
           PL+C  P+   + ++G+ S+G GC     PGVY   + +  W+
Sbjct: 408 PLVC--PDGDTWRLVGVVSWGRGCAEPNHPGVYAKVAEFLDWI 448


>gi|110815798 ovochymase 1 [Homo sapiens]
          Length = 1134

 Score =  157 bits (397), Expect = 1e-38
 Identities = 88/253 (34%), Positives = 129/253 (50%), Gaps = 9/253 (3%)

Query: 64  CGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHC 123
           CG  P        RI GG EA    WPW V L+        + CGG ++   W+LTAAHC
Sbjct: 561 CGIPPFSPQWLSRRIAGGEEACPHCWPWQVGLRFLGD----YQCGGAIINPVWILTAAHC 616

Query: 124 TKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRY 183
            +  ++PL WT + G ++ + +    +  + K II+H +F   SY +DIAL  L   + Y
Sbjct: 617 VQLKNNPLSWTIIAGDHDRNLKESTEQVRRAKHIIVHEDFNTLSYDSDIALIQLSSPLEY 676

Query: 184 NDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSE--R 241
           N  ++P+CLP    + L  +  C ++GWG    +G   + LQ  +VH + RE+C      
Sbjct: 677 NSVVRPVCLPHSA-EPLFSSEICAVTGWGSISADGGLASRLQQIQVHVLEREVCEHTYYS 735

Query: 242 SYGGIIPNTSFCAG-DEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFP 300
           ++ G I     CAG    G  D C+GDSGGPL+C   E   F + GI S+G GC +   P
Sbjct: 736 AHPGGITEKMICAGFAASGEKDFCQGDSGGPLVC-RHENGPFVLYGIVSWGAGCVQPWKP 794

Query: 301 GVYIGPSFYQKWL 313
           GV+     +  W+
Sbjct: 795 GVFARVMIFLDWI 807



 Score =  123 bits (308), Expect = 3e-28
 Identities = 83/268 (30%), Positives = 128/268 (47%), Gaps = 29/268 (10%)

Query: 76  SRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHCTKDASDPLMW-- 133
           SRI     +     PW VSL+        H CGG+L++E  V+TAAHC    S+  +   
Sbjct: 45  SRISSWRNSTVTGHPWQVSLKSDEH----HFCGGSLIQEDRVVTAAHCLDSLSEKQLKNI 100

Query: 134 TAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVN-DIALFHLKKAVRYNDYIQPICL 192
           T   G  ++  +    + I +  II HP +    Y++ DIAL +LK  V++ + +QPICL
Sbjct: 101 TVTSGEYSLFQKDKQEQNIPVSKIITHPEYNSREYMSPDIALLYLKHKVKFGNAVQPICL 160

Query: 193 PFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSYGGIIP--NT 250
           P D    ++    C  SGWG+  +    +N+LQ+ E+  +    CN+      + P   T
Sbjct: 161 P-DSDDKVEPGILCLSSGWGKISKTSEYSNVLQEMELPIMDDRACNTVLKSMNLPPLGRT 219

Query: 251 SFCAGDEDGAFDTCRGDSGGPLMCYLPEYKR----FFVMGITSYGHGCGRRGFP------ 300
             CAG  D   D C+GDSGGPL+C     +R    + + GITS+  GC     P      
Sbjct: 220 MLCAGFPDWGMDACQGDSGGPLVC-----RRGGGIWILAGITSWVAGCAGGSVPVRNNHV 274

Query: 301 ----GVYIGPSFYQKWLTEHFFHASTQG 324
               G++   S    ++T++ F    +G
Sbjct: 275 KASLGIFSKVSELMDFITQNLFTGLDRG 302


>gi|40254871 transmembrane protease, serine 11E [Homo sapiens]
          Length = 423

 Score =  156 bits (395), Expect = 2e-38
 Identities = 87/251 (34%), Positives = 127/251 (50%), Gaps = 10/251 (3%)

Query: 64  CGTAPLKDVLQGSRIIGGTEAQAGAWPWVVSLQIKYGRVLVHVCGGTLVRERWVLTAAHC 123
           CGT   K + Q  RI+GGTE + G WPW  SLQ        H CG TL+   W+++AAHC
Sbjct: 178 CGTRRSKTLGQSLRIVGGTEVEEGEWPWQASLQWDGS----HRCGATLINATWLVSAAHC 233

Query: 124 TKDASDPLMWTAVIGTNNIHGRYPHTKKIKIKAIIIHPNFILESYVNDIALFHLKKAVRY 183
                +P  WTA  G        P   K  ++ II+H  +   S+  DI+L  L   V Y
Sbjct: 234 FTTYKNPARWTASFGVTI----KPSKMKRGLRRIIVHEKYKHPSHDYDISLAELSSPVPY 289

Query: 184 NDYIQPICLPFDVFQILDGNTKCFISGWGRTKEEGNATNILQDAEVHYISREMCNSERSY 243
            + +  +CLP   ++   G+   F++G+G  K +G + N L+ A+V  I    CN  ++Y
Sbjct: 290 TNAVHRVCLPDASYEFQPGDVM-FVTGFGALKNDGYSQNHLRQAQVTLIDATTCNEPQAY 348

Query: 244 GGIIPNTSFCAGDEDGAFDTCRGDSGGPLMCYLPEYKRFFVMGITSYGHGCGRRGFPGVY 303
              I     CAG  +G  D C+GDSGGPL+        +++ GI S+G  C +   PGVY
Sbjct: 349 NDAITPRMLCAGSLEGKTDACQGDSGGPLVS-SDARDIWYLAGIVSWGDECAKPNKPGVY 407

Query: 304 IGPSFYQKWLT 314
              +  + W+T
Sbjct: 408 TRVTALRDWIT 418


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.324    0.140    0.450 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 14,322,375
Number of Sequences: 37866
Number of extensions: 682290
Number of successful extensions: 2416
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 172
Number of HSP's successfully gapped in prelim test: 5
Number of HSP's that attempted gapping in prelim test: 1634
Number of HSP's gapped (non-prelim): 200
length of query: 348
length of database: 18,247,518
effective HSP length: 103
effective length of query: 245
effective length of database: 14,347,320
effective search space: 3515093400
effective search space used: 3515093400
T: 11
A: 40
X1: 15 ( 7.0 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.