BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|31083315 G protein-coupled receptor 45 [Homo sapiens] (372 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|31083315 G protein-coupled receptor 45 [Homo sapiens] 742 0.0 gi|221139879 G protein-coupled receptor 63 [Homo sapiens] 404 e-113 gi|13540557 G protein-coupled receptor 63 [Homo sapiens] 404 e-113 gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] 118 1e-26 gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] 118 1e-26 gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] 118 1e-26 gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] 118 1e-26 gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] 118 1e-26 gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] 118 1e-26 gi|157426873 tachykinin receptor 2 [Homo sapiens] 117 2e-26 gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] 112 4e-25 gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 110 3e-24 gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 110 3e-24 gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 110 3e-24 gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 110 3e-24 gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] 109 3e-24 gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] 109 3e-24 gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] 109 3e-24 gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] 107 2e-23 gi|62865887 G protein-coupled receptor 54 [Homo sapiens] 106 3e-23 gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] 103 2e-22 gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens] 102 4e-22 gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens] 102 7e-22 gi|7669548 tachykinin receptor 3 [Homo sapiens] 102 7e-22 gi|4503383 dopamine receptor D1 [Homo sapiens] 101 9e-22 gi|4758474 G protein-coupled receptor 10 [Homo sapiens] 100 2e-21 gi|11545887 neuropeptide FF receptor 1 [Homo sapiens] 99 5e-21 gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 99 6e-21 gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] 99 8e-21 gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] 99 8e-21 >gi|31083315 G protein-coupled receptor 45 [Homo sapiens] Length = 372 Score = 742 bits (1915), Expect = 0.0 Identities = 372/372 (100%), Positives = 372/372 (100%) Query: 1 MACNSTSLEAYTYLLLNTSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVY 60 MACNSTSLEAYTYLLLNTSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVY Sbjct: 1 MACNSTSLEAYTYLLLNTSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVY 60 Query: 61 QRPAMRSAINLLLATLAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLE 120 QRPAMRSAINLLLATLAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLE Sbjct: 61 QRPAMRSAINLLLATLAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLE 120 Query: 121 GVAILLIISVDRFLIIVQRQDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAP 180 GVAILLIISVDRFLIIVQRQDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAP Sbjct: 121 GVAILLIISVDRFLIIVQRQDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAP 180 Query: 181 QCVLGYTELPADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQ 240 QCVLGYTELPADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQ Sbjct: 181 QCVLGYTELPADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQ 240 Query: 241 LTRAGLRRLQRQQQVSVDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGS 300 LTRAGLRRLQRQQQVSVDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGS Sbjct: 241 LTRAGLRRLQRQQQVSVDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGS 300 Query: 301 SFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELLPQTFQILPKVPERIRRRIQPS 360 SFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELLPQTFQILPKVPERIRRRIQPS Sbjct: 301 SFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELLPQTFQILPKVPERIRRRIQPS 360 Query: 361 TVYVCNENQSAV 372 TVYVCNENQSAV Sbjct: 361 TVYVCNENQSAV 372 >gi|221139879 G protein-coupled receptor 63 [Homo sapiens] Length = 419 Score = 404 bits (1039), Expect = e-113 Identities = 190/344 (55%), Positives = 262/344 (76%) Query: 29 LPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCM 88 L PL+I+L+ +M+ + V FLGN VVC++VYQ+ AMRSAIN+LLA+LAF+D++L++ M Sbjct: 76 LNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNM 135 Query: 89 PFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQDKLNPRRA 148 PF VT++T RW FG FCR+SA +W FV+EGVAILLIIS+DRFLIIVQRQDKLNP RA Sbjct: 136 PFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQRQDKLNPYRA 195 Query: 149 KVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTELPADRAYVVTLVVAVFFAPF 208 KV+IAVSW SFC+A P G +++P+RAPQCV GYT P +AYV+ + + FF PF Sbjct: 196 KVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPF 255 Query: 209 GVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRAGLRRLQRQQQVSVDLSFKTKAFTT 268 V+L ++M ILNT+R NA+R+H+ + + L Q ++ GL LQR Q+S+D+ FKT+AFTT Sbjct: 256 LVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTT 315 Query: 269 ILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATSTCVLWLSYLKSVFNPIVYCWRI 328 ILILF F +CW P + YSL++ FS+ FY +F+ ST +LWL YLKS NP++Y WRI Sbjct: 316 ILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIYYWRI 375 Query: 329 KKFREACIELLPQTFQILPKVPERIRRRIQPSTVYVCNENQSAV 372 KKF +AC++++P++F+ LP++P +RRI+PS VYVC E+++ V Sbjct: 376 KKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 419 >gi|13540557 G protein-coupled receptor 63 [Homo sapiens] Length = 419 Score = 404 bits (1039), Expect = e-113 Identities = 190/344 (55%), Positives = 262/344 (76%) Query: 29 LPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCM 88 L PL+I+L+ +M+ + V FLGN VVC++VYQ+ AMRSAIN+LLA+LAF+D++L++ M Sbjct: 76 LNLPLQITLSAIMIFILFVSFLGNLVVCLMVYQKAAMRSAINILLASLAFADMLLAVLNM 135 Query: 89 PFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQDKLNPRRA 148 PF VT++T RW FG FCR+SA +W FV+EGVAILLIIS+DRFLIIVQRQDKLNP RA Sbjct: 136 PFALVTILTTRWIFGKFFCRVSAMFFWLFVIEGVAILLIISIDRFLIIVQRQDKLNPYRA 195 Query: 149 KVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTELPADRAYVVTLVVAVFFAPF 208 KV+IAVSW SFC+A P G +++P+RAPQCV GYT P +AYV+ + + FF PF Sbjct: 196 KVLIAVSWATSFCVAFPLAVGNPDLQIPSRAPQCVFGYTTNPGYQAYVILISLISFFIPF 255 Query: 209 GVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRAGLRRLQRQQQVSVDLSFKTKAFTT 268 V+L ++M ILNT+R NA+R+H+ + + L Q ++ GL LQR Q+S+D+ FKT+AFTT Sbjct: 256 LVILYSFMGILNTLRHNALRIHSYPEGICLSQASKLGLMSLQRPFQMSIDMGFKTRAFTT 315 Query: 269 ILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATSTCVLWLSYLKSVFNPIVYCWRI 328 ILILF F +CW P + YSL++ FS+ FY +F+ ST +LWL YLKS NP++Y WRI Sbjct: 316 ILILFAVFIVCWAPFTTYSLVATFSKHFYYQHNFFEISTWLLWLCYLKSALNPLIYYWRI 375 Query: 329 KKFREACIELLPQTFQILPKVPERIRRRIQPSTVYVCNENQSAV 372 KKF +AC++++P++F+ LP++P +RRI+PS VYVC E+++ V Sbjct: 376 KKFHDACLDMMPKSFKFLPQLPGHTKRRIRPSAVYVCGEHRTVV 419 >gi|94421462 serotonin 5-HT4 receptor isoform n [Homo sapiens] Length = 359 Score = 118 bits (295), Expect = 1e-26 Identities = 88/339 (25%), Positives = 156/339 (46%), Gaps = 30/339 (8%) Query: 16 LNTSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLAT 75 L+ + +S+ G + + ++ ++LM ++G L V+ + + R + N + + Sbjct: 4 LDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNL--LVMVAVCWDRQLRKIKTNYFIVS 61 Query: 76 LAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLI 135 LAF+D+++S+ MPF A+ L+ W +G+ FC + +L + L IS+DR+ Sbjct: 62 LAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYA 121 Query: 136 I----VQRQDKLNPRRAKVIIAVSWVL-SFCIAGPSLTGWT------LVEVPARAPQCVL 184 I + ++K+ P R +++ WV+ +F P + GW L+E Sbjct: 122 ICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNS 181 Query: 185 GYTELPADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRA 244 Y ++ Y +T V F+ PF +M+ AY I T +++A ++ + L RA Sbjct: 182 TYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRA 232 Query: 245 GLRRLQRQQQVSVD----LSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGS 300 G R Q + +TKA T+ I+ F LCW P V +++ F G Sbjct: 233 GASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQ 292 Query: 301 SFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELL 339 + T LWL Y+ S NP +Y + K FR A + +L Sbjct: 293 VW----TAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327 >gi|94421460 serotonin 5-HT4 receptor isoform i [Homo sapiens] Length = 428 Score = 118 bits (295), Expect = 1e-26 Identities = 88/339 (25%), Positives = 156/339 (46%), Gaps = 30/339 (8%) Query: 16 LNTSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLAT 75 L+ + +S+ G + + ++ ++LM ++G L V+ + + R + N + + Sbjct: 4 LDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNL--LVMVAVCWDRQLRKIKTNYFIVS 61 Query: 76 LAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLI 135 LAF+D+++S+ MPF A+ L+ W +G+ FC + +L + L IS+DR+ Sbjct: 62 LAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYA 121 Query: 136 I----VQRQDKLNPRRAKVIIAVSWVL-SFCIAGPSLTGWT------LVEVPARAPQCVL 184 I + ++K+ P R +++ WV+ +F P + GW L+E Sbjct: 122 ICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNS 181 Query: 185 GYTELPADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRA 244 Y ++ Y +T V F+ PF +M+ AY I T +++A ++ + L RA Sbjct: 182 TYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRA 232 Query: 245 GLRRLQRQQQVSVD----LSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGS 300 G R Q + +TKA T+ I+ F LCW P V +++ F G Sbjct: 233 GASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQ 292 Query: 301 SFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELL 339 + T LWL Y+ S NP +Y + K FR A + +L Sbjct: 293 VW----TAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327 >gi|94421456 serotonin 5-HT4 receptor isoform d [Homo sapiens] Length = 360 Score = 118 bits (295), Expect = 1e-26 Identities = 88/339 (25%), Positives = 156/339 (46%), Gaps = 30/339 (8%) Query: 16 LNTSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLAT 75 L+ + +S+ G + + ++ ++LM ++G L V+ + + R + N + + Sbjct: 4 LDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNL--LVMVAVCWDRQLRKIKTNYFIVS 61 Query: 76 LAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLI 135 LAF+D+++S+ MPF A+ L+ W +G+ FC + +L + L IS+DR+ Sbjct: 62 LAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYA 121 Query: 136 I----VQRQDKLNPRRAKVIIAVSWVL-SFCIAGPSLTGWT------LVEVPARAPQCVL 184 I + ++K+ P R +++ WV+ +F P + GW L+E Sbjct: 122 ICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNS 181 Query: 185 GYTELPADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRA 244 Y ++ Y +T V F+ PF +M+ AY I T +++A ++ + L RA Sbjct: 182 TYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRA 232 Query: 245 GLRRLQRQQQVSVD----LSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGS 300 G R Q + +TKA T+ I+ F LCW P V +++ F G Sbjct: 233 GASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQ 292 Query: 301 SFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELL 339 + T LWL Y+ S NP +Y + K FR A + +L Sbjct: 293 VW----TAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327 >gi|94421454 serotonin 5-HT4 receptor isoform a [Homo sapiens] Length = 387 Score = 118 bits (295), Expect = 1e-26 Identities = 88/339 (25%), Positives = 156/339 (46%), Gaps = 30/339 (8%) Query: 16 LNTSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLAT 75 L+ + +S+ G + + ++ ++LM ++G L V+ + + R + N + + Sbjct: 4 LDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNL--LVMVAVCWDRQLRKIKTNYFIVS 61 Query: 76 LAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLI 135 LAF+D+++S+ MPF A+ L+ W +G+ FC + +L + L IS+DR+ Sbjct: 62 LAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYA 121 Query: 136 I----VQRQDKLNPRRAKVIIAVSWVL-SFCIAGPSLTGWT------LVEVPARAPQCVL 184 I + ++K+ P R +++ WV+ +F P + GW L+E Sbjct: 122 ICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNS 181 Query: 185 GYTELPADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRA 244 Y ++ Y +T V F+ PF +M+ AY I T +++A ++ + L RA Sbjct: 182 TYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRA 232 Query: 245 GLRRLQRQQQVSVD----LSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGS 300 G R Q + +TKA T+ I+ F LCW P V +++ F G Sbjct: 233 GASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQ 292 Query: 301 SFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELL 339 + T LWL Y+ S NP +Y + K FR A + +L Sbjct: 293 VW----TAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327 >gi|41282074 serotonin 5-HT4 receptor isoform g [Homo sapiens] Length = 378 Score = 118 bits (295), Expect = 1e-26 Identities = 88/339 (25%), Positives = 156/339 (46%), Gaps = 30/339 (8%) Query: 16 LNTSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLAT 75 L+ + +S+ G + + ++ ++LM ++G L V+ + + R + N + + Sbjct: 4 LDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNL--LVMVAVCWDRQLRKIKTNYFIVS 61 Query: 76 LAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLI 135 LAF+D+++S+ MPF A+ L+ W +G+ FC + +L + L IS+DR+ Sbjct: 62 LAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYA 121 Query: 136 I----VQRQDKLNPRRAKVIIAVSWVL-SFCIAGPSLTGWT------LVEVPARAPQCVL 184 I + ++K+ P R +++ WV+ +F P + GW L+E Sbjct: 122 ICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNS 181 Query: 185 GYTELPADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRA 244 Y ++ Y +T V F+ PF +M+ AY I T +++A ++ + L RA Sbjct: 182 TYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRA 232 Query: 245 GLRRLQRQQQVSVD----LSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGS 300 G R Q + +TKA T+ I+ F LCW P V +++ F G Sbjct: 233 GASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQ 292 Query: 301 SFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELL 339 + T LWL Y+ S NP +Y + K FR A + +L Sbjct: 293 VW----TAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327 >gi|11321563 serotonin 5-HT4 receptor isoform b [Homo sapiens] Length = 388 Score = 118 bits (295), Expect = 1e-26 Identities = 88/339 (25%), Positives = 156/339 (46%), Gaps = 30/339 (8%) Query: 16 LNTSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLAT 75 L+ + +S+ G + + ++ ++LM ++G L V+ + + R + N + + Sbjct: 4 LDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNL--LVMVAVCWDRQLRKIKTNYFIVS 61 Query: 76 LAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLI 135 LAF+D+++S+ MPF A+ L+ W +G+ FC + +L + L IS+DR+ Sbjct: 62 LAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYA 121 Query: 136 I----VQRQDKLNPRRAKVIIAVSWVL-SFCIAGPSLTGWT------LVEVPARAPQCVL 184 I + ++K+ P R +++ WV+ +F P + GW L+E Sbjct: 122 ICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLIEKRKFNQNSNS 181 Query: 185 GYTELPADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRA 244 Y ++ Y +T V F+ PF +M+ AY I T +++A ++ + L RA Sbjct: 182 TYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI---------QMLQRA 232 Query: 245 GLRRLQRQQQVSVD----LSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGS 300 G R Q + +TKA T+ I+ F LCW P V +++ F G Sbjct: 233 GASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVTNIVDPFIDYTVPGQ 292 Query: 301 SFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELL 339 + T LWL Y+ S NP +Y + K FR A + +L Sbjct: 293 VW----TAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 327 >gi|157426873 tachykinin receptor 2 [Homo sapiens] Length = 398 Score = 117 bits (293), Expect = 2e-26 Identities = 80/318 (25%), Positives = 141/318 (44%), Gaps = 24/318 (7%) Query: 19 SNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAF 78 SN + + +P+ A L + +V GN +V I+ MR+ N + LA Sbjct: 18 SNTTGITAFSMPSWQLALWATAYLALVLVAVTGNAIVIWIILAHRRMRTVTNYFIVNLAL 77 Query: 79 SDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQ 138 +D+ ++ F V W+FG FC + + + I+ DR++ IV Sbjct: 78 ADLCMAAFNAAFNFVYASHNIWYFGRAFCYFQNLFPITAMFVSIYSMTAIAADRYMAIVH 137 Query: 139 R-QDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTELPADRA--- 194 Q +L+ K +IA W+++ +A P ++ V + A +CV+ + E + Sbjct: 138 PFQPRLSAPSTKAVIAGIWLVALALASPQCF-YSTVTMDQGATKCVVAWPEDSGGKTLLL 196 Query: 195 YVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRAGLRRLQRQQQ 254 Y + ++ ++F P VM AY I T+ + AV H Q A LR LQ + Sbjct: 197 YHLVVIALIYFLPLAVMFVAYSVIGLTLWRRAVPGH---------QAHGANLRHLQAMK- 246 Query: 255 VSVDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATSTCVLWLSY 314 K T++++ + F++CWLP+ +Y +L F + YC + WL+ Sbjct: 247 ---------KFVKTMVLVVLTFAICWLPYHLYFILGSFQEDIYCHKFIQQVYLALFWLAM 297 Query: 315 LKSVFNPIVYCWRIKKFR 332 +++NPI+YC +FR Sbjct: 298 SSTMYNPIIYCCLNHRFR 315 >gi|94421458 serotonin 5-HT4 receptor isoform hb [Homo sapiens] Length = 402 Score = 112 bits (281), Expect = 4e-25 Identities = 89/353 (25%), Positives = 159/353 (45%), Gaps = 44/353 (12%) Query: 16 LNTSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLAT 75 L+ + +S+ G + + ++ ++LM ++G L V+ + + R + N + + Sbjct: 4 LDANVSSEEGFGSVEKVVLLTFLSTVILMAILGNL--LVMVAVCWDRQLRKIKTNYFIVS 61 Query: 76 LAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLI 135 LAF+D+++S+ MPF A+ L+ W +G+ FC + +L + L IS+DR+ Sbjct: 62 LAFADLLVSVLVMPFGAIELVQDIWIYGEVFCLVRTSLDVLLTTASIFHLCCISLDRYYA 121 Query: 136 I----VQRQDKLNPRRAKVIIAVSWVL-SFCIAGPSLTGWTLVEV--PARAPQCVLG--- 185 I + ++K+ P R +++ WV+ +F P + GW + + R+ LG Sbjct: 122 ICCQPLVYRNKMTPLRIALMLGGCWVIPTFISFLPIMQGWNNIGIIDLERSLNQGLGQDF 181 Query: 186 ---------------YTELPADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVH 230 Y ++ Y +T V F+ PF +M+ AY I T +++A ++ Sbjct: 182 HAIEKRKFNQNSNSTYCVFMVNKPYAITCSVVAFYIPFLLMVLAYYRIYVTAKEHAHQI- 240 Query: 231 NQSDSLDLRQLTRAGLRRLQRQQQVSVD----LSFKTKAFTTILILFVGFSLCWLPHSVY 286 + L RAG R Q + +TKA T+ I+ F LCW P V Sbjct: 241 --------QMLQRAGASSESRPQSADQHSTHRMRTETKAAKTLCIIMGCFCLCWAPFFVT 292 Query: 287 SLLSVFSQRFYCGSSFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELL 339 +++ F G + T LWL Y+ S NP +Y + K FR A + +L Sbjct: 293 NIVDPFIDYTVPGQVW----TAFLWLGYINSGLNPFLYAFLNKSFRRAFLIIL 341 >gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] Length = 455 Score = 110 bits (274), Expect = 3e-24 Identities = 95/342 (27%), Positives = 158/342 (46%), Gaps = 35/342 (10%) Query: 18 TSNASDSGS-TQLPAPLRISLAIVMLL----MTVVGFLGNTVVCIIVYQRPAMRSAINLL 72 + NASDS + TQ PAP+ IS AI++ + + + G LGN +V + V + S + Sbjct: 5 SGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYY 64 Query: 73 LATLAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDR 132 + LA +D++L+ +PF+A+ + W FG FC + A + + L IIS+DR Sbjct: 65 IVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDR 124 Query: 133 FLII---VQRQDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTEL 189 ++ + ++ + RR + + W LS I+ L GW PA + + E Sbjct: 125 YIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGW---RQPAPEDETICQINEE 181 Query: 190 PADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRK---NAVRVHNQSDSLDLRQLT---- 242 P YV+ + F+ P ++L Y C + V K ++ ++D D Q+T Sbjct: 182 P---GYVLFSALGSFYLPLAIILVMY-CRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIH 237 Query: 243 -------RAGLRRLQRQQQVSVDL---SFKTKAFTTILILFVGFSLCWLPHSVYSLLSVF 292 +G+ + + SV L S + KA T+ I+ F LCWLP + + F Sbjct: 238 RKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSF 297 Query: 293 SQRFYCGSSFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREA 334 F + + V WL YL S NPI+Y ++F++A Sbjct: 298 FPDFKPSETVF---KIVFWLGYLNSCINPIIYPCSSQEFKKA 336 >gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] Length = 466 Score = 110 bits (274), Expect = 3e-24 Identities = 95/342 (27%), Positives = 158/342 (46%), Gaps = 35/342 (10%) Query: 18 TSNASDSGS-TQLPAPLRISLAIVMLL----MTVVGFLGNTVVCIIVYQRPAMRSAINLL 72 + NASDS + TQ PAP+ IS AI++ + + + G LGN +V + V + S + Sbjct: 5 SGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYY 64 Query: 73 LATLAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDR 132 + LA +D++L+ +PF+A+ + W FG FC + A + + L IIS+DR Sbjct: 65 IVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDR 124 Query: 133 FLII---VQRQDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTEL 189 ++ + ++ + RR + + W LS I+ L GW PA + + E Sbjct: 125 YIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGW---RQPAPEDETICQINEE 181 Query: 190 PADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRK---NAVRVHNQSDSLDLRQLT---- 242 P YV+ + F+ P ++L Y C + V K ++ ++D D Q+T Sbjct: 182 P---GYVLFSALGSFYLPLAIILVMY-CRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIH 237 Query: 243 -------RAGLRRLQRQQQVSVDL---SFKTKAFTTILILFVGFSLCWLPHSVYSLLSVF 292 +G+ + + SV L S + KA T+ I+ F LCWLP + + F Sbjct: 238 RKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSF 297 Query: 293 SQRFYCGSSFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREA 334 F + + V WL YL S NPI+Y ++F++A Sbjct: 298 FPDFKPSETVF---KIVFWLGYLNSCINPIIYPCSSQEFKKA 336 >gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] Length = 475 Score = 110 bits (274), Expect = 3e-24 Identities = 95/342 (27%), Positives = 158/342 (46%), Gaps = 35/342 (10%) Query: 18 TSNASDSGS-TQLPAPLRISLAIVMLL----MTVVGFLGNTVVCIIVYQRPAMRSAINLL 72 + NASDS + TQ PAP+ IS AI++ + + + G LGN +V + V + S + Sbjct: 5 SGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYY 64 Query: 73 LATLAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDR 132 + LA +D++L+ +PF+A+ + W FG FC + A + + L IIS+DR Sbjct: 65 IVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDR 124 Query: 133 FLII---VQRQDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTEL 189 ++ + ++ + RR + + W LS I+ L GW PA + + E Sbjct: 125 YIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGW---RQPAPEDETICQINEE 181 Query: 190 PADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRK---NAVRVHNQSDSLDLRQLT---- 242 P YV+ + F+ P ++L Y C + V K ++ ++D D Q+T Sbjct: 182 P---GYVLFSALGSFYLPLAIILVMY-CRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIH 237 Query: 243 -------RAGLRRLQRQQQVSVDL---SFKTKAFTTILILFVGFSLCWLPHSVYSLLSVF 292 +G+ + + SV L S + KA T+ I+ F LCWLP + + F Sbjct: 238 RKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSF 297 Query: 293 SQRFYCGSSFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREA 334 F + + V WL YL S NPI+Y ++F++A Sbjct: 298 FPDFKPSETVF---KIVFWLGYLNSCINPIIYPCSSQEFKKA 336 >gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] Length = 429 Score = 110 bits (274), Expect = 3e-24 Identities = 95/342 (27%), Positives = 158/342 (46%), Gaps = 35/342 (10%) Query: 18 TSNASDSGS-TQLPAPLRISLAIVMLL----MTVVGFLGNTVVCIIVYQRPAMRSAINLL 72 + NASDS + TQ PAP+ IS AI++ + + + G LGN +V + V + S + Sbjct: 5 SGNASDSSNCTQPPAPVNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYY 64 Query: 73 LATLAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDR 132 + LA +D++L+ +PF+A+ + W FG FC + A + + L IIS+DR Sbjct: 65 IVNLAVADLLLTSTVLPFSAIFEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDR 124 Query: 133 FLII---VQRQDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTEL 189 ++ + ++ + RR + + W LS I+ L GW PA + + E Sbjct: 125 YIGVSYPLRYPTIVTQRRGLMALLCVWALSLVISIGPLFGW---RQPAPEDETICQINEE 181 Query: 190 PADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRK---NAVRVHNQSDSLDLRQLT---- 242 P YV+ + F+ P ++L Y C + V K ++ ++D D Q+T Sbjct: 182 P---GYVLFSALGSFYLPLAIILVMY-CRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIH 237 Query: 243 -------RAGLRRLQRQQQVSVDL---SFKTKAFTTILILFVGFSLCWLPHSVYSLLSVF 292 +G+ + + SV L S + KA T+ I+ F LCWLP + + F Sbjct: 238 RKNAPAGGSGMASAKTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSF 297 Query: 293 SQRFYCGSSFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREA 334 F + + V WL YL S NPI+Y ++F++A Sbjct: 298 FPDFKPSETVF---KIVFWLGYLNSCINPIIYPCSSQEFKKA 336 >gi|10880131 5-hydroxytryptamine receptor 7 isoform b [Homo sapiens] Length = 432 Score = 109 bits (273), Expect = 3e-24 Identities = 97/337 (28%), Positives = 156/337 (46%), Gaps = 49/337 (14%) Query: 34 RISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAV 93 ++ + ++ L+T++ GN +V I V +R N L+ +LA +D+ +++ MPF +V Sbjct: 81 KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSV 140 Query: 94 T-LITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQ------RQDKLNPR 146 T LI +W FG FC + + + L +IS+DR+L I + RQ+ Sbjct: 141 TDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQN--GKC 198 Query: 147 RAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTELPADRAYVVTLVVAVFFA 206 AK+I++V W+LS I P L GW + C++ D Y + F+ Sbjct: 199 MAKMILSV-WLLSASITLPPLFGWAQNVNDDKV--CLIS-----QDFGYTIYSTAVAFYI 250 Query: 207 PFGVMLCAYMCILNTVRKNAVR------VHNQSDSLDLRQLTRAGLRRLQRQQQVSVDLS 260 P VML Y I RK+A + + DS+ + G+ +LQ++ + +LS Sbjct: 251 PMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSV----IALNGIVKLQKEVEECANLS 306 Query: 261 ------------FK--TKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATS 306 FK KA TT+ I+ F++CWLP + LLS ++ F CG+S Sbjct: 307 RLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLP---FFLLST-ARPFICGTSCSCIP 362 Query: 307 TCV----LWLSYLKSVFNPIVYCWRIKKFREACIELL 339 V LWL Y S+ NP +Y + + R LL Sbjct: 363 LWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLL 399 >gi|10880129 5-hydroxytryptamine receptor 7 isoform d [Homo sapiens] Length = 479 Score = 109 bits (273), Expect = 3e-24 Identities = 97/337 (28%), Positives = 156/337 (46%), Gaps = 49/337 (14%) Query: 34 RISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAV 93 ++ + ++ L+T++ GN +V I V +R N L+ +LA +D+ +++ MPF +V Sbjct: 81 KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSV 140 Query: 94 T-LITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQ------RQDKLNPR 146 T LI +W FG FC + + + L +IS+DR+L I + RQ+ Sbjct: 141 TDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQN--GKC 198 Query: 147 RAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTELPADRAYVVTLVVAVFFA 206 AK+I++V W+LS I P L GW + C++ D Y + F+ Sbjct: 199 MAKMILSV-WLLSASITLPPLFGWAQNVNDDKV--CLIS-----QDFGYTIYSTAVAFYI 250 Query: 207 PFGVMLCAYMCILNTVRKNAVR------VHNQSDSLDLRQLTRAGLRRLQRQQQVSVDLS 260 P VML Y I RK+A + + DS+ + G+ +LQ++ + +LS Sbjct: 251 PMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSV----IALNGIVKLQKEVEECANLS 306 Query: 261 ------------FK--TKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATS 306 FK KA TT+ I+ F++CWLP + LLS ++ F CG+S Sbjct: 307 RLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLP---FFLLST-ARPFICGTSCSCIP 362 Query: 307 TCV----LWLSYLKSVFNPIVYCWRIKKFREACIELL 339 V LWL Y S+ NP +Y + + R LL Sbjct: 363 LWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLL 399 >gi|4504547 5-hydroxytryptamine receptor 7 isoform a [Homo sapiens] Length = 445 Score = 109 bits (273), Expect = 3e-24 Identities = 97/337 (28%), Positives = 156/337 (46%), Gaps = 49/337 (14%) Query: 34 RISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAV 93 ++ + ++ L+T++ GN +V I V +R N L+ +LA +D+ +++ MPF +V Sbjct: 81 KVVIGSILTLITLLTIAGNCLVVISVCFVKKLRQPSNYLIVSLALADLSVAVAVMPFVSV 140 Query: 94 T-LITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQ------RQDKLNPR 146 T LI +W FG FC + + + L +IS+DR+L I + RQ+ Sbjct: 141 TDLIGGKWIFGHFFCNVFIAMDVMCCTASIMTLCVISIDRYLGITRPLTYPVRQN--GKC 198 Query: 147 RAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTELPADRAYVVTLVVAVFFA 206 AK+I++V W+LS I P L GW + C++ D Y + F+ Sbjct: 199 MAKMILSV-WLLSASITLPPLFGWAQNVNDDKV--CLIS-----QDFGYTIYSTAVAFYI 250 Query: 207 PFGVMLCAYMCILNTVRKNAVR------VHNQSDSLDLRQLTRAGLRRLQRQQQVSVDLS 260 P VML Y I RK+A + + DS+ + G+ +LQ++ + +LS Sbjct: 251 PMSVMLFMYYQIYKAARKSAAKHKFPGFPRVEPDSV----IALNGIVKLQKEVEECANLS 306 Query: 261 ------------FK--TKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATS 306 FK KA TT+ I+ F++CWLP + LLS ++ F CG+S Sbjct: 307 RLLKHERKNISIFKREQKAATTLGIIVGAFTVCWLP---FFLLST-ARPFICGTSCSCIP 362 Query: 307 TCV----LWLSYLKSVFNPIVYCWRIKKFREACIELL 339 V LWL Y S+ NP +Y + + R LL Sbjct: 363 LWVERTFLWLGYANSLINPFIYAFFNRDLRTTYRSLL 399 >gi|4501969 adrenergic, beta-2-, receptor, surface [Homo sapiens] Length = 413 Score = 107 bits (267), Expect = 2e-23 Identities = 82/338 (24%), Positives = 149/338 (44%), Gaps = 27/338 (7%) Query: 17 NTSNASDSGSTQLPAPLRI-SLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLAT 75 N S+A D TQ + + + IVM L+ + GN +V + + +++ N + + Sbjct: 15 NRSHAPDHDVTQQRDEVWVVGMGIVMSLIVLAIVFGNVLVITAIAKFERLQTVTNYFITS 74 Query: 76 LAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLI 135 LA +D+++ L +PF A ++ W FG+ +C ++ V + L +I+VDR+ Sbjct: 75 LACADLVMGLAVVPFGAAHILMKMWTFGNFWCEFWTSIDVLCVTASIETLCVIAVDRYFA 134 Query: 136 IV---QRQDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYT--ELP 190 I + Q L +A+VII + W++S + + A C T + Sbjct: 135 ITSPFKYQSLLTKNKARVIILMVWIVSGLTSFLPIQMHWYRATHQEAINCYANETCCDFF 194 Query: 191 ADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRA------ 244 ++AY + + F+ P +M+ Y + ++ ++ ++ L++ Sbjct: 195 TNQAYAIASSIVSFYVPLVIMVFVYSRVFQEAKRQLQKIDKSEGRFHVQNLSQVEQDGRT 254 Query: 245 --GLRRLQRQQQVSVDLSFKT-KAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSS 301 GLRR S K KA T+ I+ F+LCWLP + +++ V Sbjct: 255 GHGLRR-------SSKFCLKEHKALKTLGIIMGTFTLCWLPFFIVNIVHVIQDNLIRKEV 307 Query: 302 FYATSTCVLWLSYLKSVFNPIVYCWRIKKFREACIELL 339 + + W+ Y+ S FNP++YC R FR A ELL Sbjct: 308 YILLN----WIGYVNSGFNPLIYC-RSPDFRIAFQELL 340 >gi|62865887 G protein-coupled receptor 54 [Homo sapiens] Length = 398 Score = 106 bits (265), Expect = 3e-23 Identities = 89/347 (25%), Positives = 149/347 (42%), Gaps = 33/347 (9%) Query: 19 SNASDSGSTQLPAPLRISLAIVMLL---MTVVGFLGNTVVCIIVYQRPAMRSAINLLLAT 75 +NASD +P+P + +V L + ++G +GN++V ++ + MR+ N +A Sbjct: 27 ANASDG---PVPSPRAVDAWLVPLFFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIAN 83 Query: 76 LAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLI 135 LA +D+ LCC+PFTA+ W GD C+ + V A L +SVDR+ + Sbjct: 84 LAATDVTFLLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQVSVQATCATLTAMSVDRWYV 143 Query: 136 IVQRQDKLNPRRAKVIIAVS---WVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTELPAD 192 V L+ R ++ +AVS WV S ++ P L L P C + + Sbjct: 144 TVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLALHRL--SPGPRAYCSEAFPSRALE 201 Query: 193 RAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLT-RAGLRRLQR 251 RA+ + ++A++ P Y +L + + AVR +L + L RAG Sbjct: 202 RAFALYNLLALYLLPLLATCACYAAMLRHLGRVAVRPAPADSALQGQVLAERAG------ 255 Query: 252 QQQVSVDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATSTCVLW 311 + + K + + + F+ CW P ++ +L YA W Sbjct: 256 --------AVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPAGSWHPRSYAAYALKTW 307 Query: 312 ---LSYLKSVFNPIVYCWRIKKFREACIELLPQTFQILPKVPERIRR 355 +SY S NP++Y + FR+A + P P+ P R RR Sbjct: 308 AHCMSYSNSALNPLLYAFLGSHFRQAFRRVCP----CAPRRPRRPRR 350 >gi|4507343 tachykinin receptor 1 isoform long [Homo sapiens] Length = 407 Score = 103 bits (258), Expect = 2e-22 Identities = 75/319 (23%), Positives = 140/319 (43%), Gaps = 25/319 (7%) Query: 18 TSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLA 77 ++N S+ PA + A ++ V +GN VV I+ MR+ N L LA Sbjct: 16 STNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLA 75 Query: 78 FSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIV 137 F++ ++ + W++G +C+ V + + ++ DR++ I+ Sbjct: 76 FAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAII 135 Query: 138 QR-QDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTELPA---DR 193 Q +L+ KV+I V WVL+ +A P T +P+R C++ + E P ++ Sbjct: 136 HPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVV-CMIEWPEHPNKIYEK 194 Query: 194 AYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRAGLRRLQRQQ 253 Y + + V ++F P V+ AY + T+ + + DS D + + Sbjct: 195 VYHICVTVLIYFLPLLVIGYAYTVVGITLWASEI----PGDSSD------------RYHE 238 Query: 254 QVSVDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATSTCVLWLS 313 QVS K K ++++ F++CWLP ++ LL + Y ++WL+ Sbjct: 239 QVSA----KRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLA 294 Query: 314 YLKSVFNPIVYCWRIKKFR 332 +++NPI+YC +FR Sbjct: 295 MSSTMYNPIIYCCLNDRFR 313 >gi|4505445 neuropeptide Y receptor Y1 [Homo sapiens] Length = 384 Score = 102 bits (255), Expect = 4e-22 Identities = 76/323 (23%), Positives = 151/323 (46%), Gaps = 32/323 (9%) Query: 21 ASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSD 80 A ++ LP + +LA+ + ++G GN + II+ ++ MR+ N+L+ L+FSD Sbjct: 27 AFENDDCHLPLAMIFTLALAYGAVIILGVSGNLALIIIILKQKEMRNVTNILIVNLSFSD 86 Query: 81 IMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRF-LIIVQR 139 +++++ C+PFT V + W FG+ C+L+ + + + L++I+V+R LII R Sbjct: 87 LLVAIMCLPFTFVYTLMDHWVFGEAMCKLNPFVQCVSITVSIFSLVLIAVERHQLIINPR 146 Query: 140 QDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEVPAR------APQCVLGYTELPADR 193 + N R A V IAV WVL+ + P L + + P + + + + P+D Sbjct: 147 GWRPNNRHAYVGIAVIWVLAVASSLPFLIYQVMTDEPFQNVTLDAYKDKYVCFDQFPSDS 206 Query: 194 ---AYVVTLVVAVFFAPF-GVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRAGLRRL 249 +Y L+V +F P + +C + + R+N N D + R R Sbjct: 207 HRLSYTTLLLVLQYFGPLCFIFICYFKIYIRLKRRN-----NMMDKM------RDNKYRS 255 Query: 250 QRQQQVSVDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATSTCV 309 +++++ +L + V F++CWLP ++++ + ++ + + Sbjct: 256 SETKRINI----------MLLSIVVAFAVCWLPLTIFNTVFDWNHQIIATCNHNLLFLLC 305 Query: 310 LWLSYLKSVFNPIVYCWRIKKFR 332 + + + NPI Y + K F+ Sbjct: 306 HLTAMISTCVNPIFYGFLNKNFQ 328 >gi|7669546 tachykinin receptor 1 isoform short [Homo sapiens] Length = 311 Score = 102 bits (253), Expect = 7e-22 Identities = 73/312 (23%), Positives = 137/312 (43%), Gaps = 25/312 (8%) Query: 18 TSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLA 77 ++N S+ PA + A ++ V +GN VV I+ MR+ N L LA Sbjct: 16 STNTSEPNQFVQPAWQIVLWAAAYTVIVVTSVVGNVVVMWIILAHKRMRTVTNYFLVNLA 75 Query: 78 FSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIV 137 F++ ++ + W++G +C+ V + + ++ DR++ I+ Sbjct: 76 FAEASMAAFNTVVNFTYAVHNEWYYGLFYCKFHNFFPIAAVFASIYSMTAVAFDRYMAII 135 Query: 138 QR-QDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEVPARAPQCVLGYTELPA---DR 193 Q +L+ KV+I V WVL+ +A P T +P+R C++ + E P ++ Sbjct: 136 HPLQPRLSATATKVVICVIWVLALLLAFPQGYYSTTETMPSRVV-CMIEWPEHPNKIYEK 194 Query: 194 AYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRAGLRRLQRQQ 253 Y + + V ++F P V+ AY + T+ + + DS D + + Sbjct: 195 VYHICVTVLIYFLPLLVIGYAYTVVGITLWASEI----PGDSSD------------RYHE 238 Query: 254 QVSVDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATSTCVLWLS 313 QVS K K ++++ F++CWLP ++ LL + Y ++WL+ Sbjct: 239 QVSA----KRKVVKMMIVVVCTFAICWLPFHIFFLLPYINPDLYLKKFIQQVYLAIMWLA 294 Query: 314 YLKSVFNPIVYC 325 +++NPI+YC Sbjct: 295 MSSTMYNPIIYC 306 >gi|7669548 tachykinin receptor 3 [Homo sapiens] Length = 465 Score = 102 bits (253), Expect = 7e-22 Identities = 72/295 (24%), Positives = 127/295 (43%), Gaps = 29/295 (9%) Query: 43 LMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAVTLITVRWHF 102 ++ V LGN +V I+ MR+ N L LAFSD ++ + + W+F Sbjct: 94 VVVAVAVLGNLIVIWIILAHKRMRTVTNYFLVNLAFSDASMAAFNTLVNFIYALHSEWYF 153 Query: 103 GDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQRQDKLNPRRA----KVIIAVSWVL 158 G ++CR V + + I+VDR++ I+ D L PR + K++I W+L Sbjct: 154 GANYCRFQNFFPITAVFASIYSMTAIAVDRYMAII---DPLKPRLSATATKIVIGSIWIL 210 Query: 159 SFCIAGPSLTGWTLVEVPARAPQCVLGYTELPADR-AYVVTLVVAVFFAPFGVMLCAYMC 217 +F +A P +P R C + + E P Y + +++ V+ P +M Y Sbjct: 211 AFLLAFPQCLYSKTKVMPGRT-LCFVQWPEGPKQHFTYHIIVIILVYCFPLLIMGITYTI 269 Query: 218 ILNTVRKNAVRVHNQSDSLDLRQLTRAGLRRLQRQQQVSVDLSFKTKAFTTILILFVGFS 277 + T+ + D+ D + L K K ++I+ + F+ Sbjct: 270 VGITLWGGEI----PGDTCD----------------KYHEQLKAKRKVVKMMIIVVMTFA 309 Query: 278 LCWLPHSVYSLLSVFSQRFYCGSSFYATSTCVLWLSYLKSVFNPIVYCWRIKKFR 332 +CWLP+ +Y +L+ Q+ WL+ +++NPI+YC K+FR Sbjct: 310 ICWLPYHIYFILTAIYQQLNRWKYIQQVYLASFWLAMSSTMYNPIIYCCLNKRFR 364 >gi|4503383 dopamine receptor D1 [Homo sapiens] Length = 446 Score = 101 bits (252), Expect = 9e-22 Identities = 97/356 (27%), Positives = 156/356 (43%), Gaps = 34/356 (9%) Query: 16 LNTSNASDSGST-QLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAI-NLLL 73 LNTS +G + +RI A + L+ + LGNT+VC V + +RS + N + Sbjct: 4 LNTSAMDGTGLVVERDFSVRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNFFV 63 Query: 74 ATLAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRF 133 +LA SD+++++ MP+ AV I W FG FC + + L +ISVDR+ Sbjct: 64 ISLAVSDLLVAVLVMPWKAVAEIAGFWPFGS-FCNIWVAFDIMCSTASILNLCVISVDRY 122 Query: 134 LII---VQRQDKLNPRRAKVIIAVSWVLSFCIAG-PSLTGWTLVE--VPARAPQCVLGYT 187 I + + K+ P+ A ++I+V+W LS I+ P W + P+ L T Sbjct: 123 WAISSPFRYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTSPSDGNATSLAET 182 Query: 188 ----ELPADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRV----HNQSDSLDLR 239 + R Y ++ V F+ P +M+ Y I +K R+ + + + Sbjct: 183 IDNCDSSLSRTYAISSSVISFYIPVAIMIVTYTRIYRIAQKQIRRIAALERAAVHAKNCQ 242 Query: 240 QLTRAGLRRLQRQQQVSVDLSFK--TKAFTTILILFVGFSLCWLPHSVYSLLSVF----- 292 T G Q + S +SFK TK T+ ++ F CWLP + + + F Sbjct: 243 TTTGNGKPVECSQPESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFILNCILPFCGSGE 302 Query: 293 SQRFYCGSSFYATSTCVLWLSYLKSVFNPIVYCWRIKKFREA------CIELLPQT 342 +Q F S+ T +W + S NPI+Y + FR+A C L P T Sbjct: 303 TQPFCIDSN---TFDVFVWFGWANSSLNPIIYAFN-ADFRKAFSTLLGCYRLCPAT 354 >gi|4758474 G protein-coupled receptor 10 [Homo sapiens] Length = 370 Score = 100 bits (250), Expect = 2e-21 Identities = 82/318 (25%), Positives = 140/318 (44%), Gaps = 23/318 (7%) Query: 26 STQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSL 85 S QL L+ + ++ ++ VVG +GN ++ +++ + + + N L+ LA SD+++ Sbjct: 52 SLQLVHQLKGLIVLLYSVVVVVGLVGNCLLVLVIARVRRLHNVTNFLIGNLALSDVLMCT 111 Query: 86 CCMPFTAVTLITVR-WHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLIIVQ-RQDKL 143 C+P T R W FG C L L V V L I+VDR++++V + ++ Sbjct: 112 ACVPLTLAYAFEPRGWVFGGGLCHLVFFLQPVTVYVSVFTLTTIAVDRYVVLVHPLRRRI 171 Query: 144 NPRRAKVIIAVSWVLSFCIAGPSLTGWTLVEV-PARAPQCVLGYTELPADR-AYVVTLVV 201 + R + + W LS +A P+ VE+ P C + R Y L++ Sbjct: 172 SLRLSAYAVLAIWALSAVLALPAAVHTYHVELKPHDVRLCEEFWGSQERQRQLYAWGLLL 231 Query: 202 AVFFAPFGVMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRAGLRRLQRQQQVSVDLSF 261 + P V+L +Y VRV S+ LR G Q Q D + Sbjct: 232 VTYLLPLLVILLSY-----------VRV-----SVKLRNRVVPG---CVTQSQADWDRAR 272 Query: 262 KTKAFTTILILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFYATSTCVLWLSYLKSVFNP 321 + + F ++++ V F++CWLP V++LL +F WL+ + +NP Sbjct: 273 RRRTFCLLVVVVVVFAVCWLPLHVFNLLRDLDPHAIDPYAFGLVQLLCHWLAMSSACYNP 332 Query: 322 IVYCWRIKKFREACIELL 339 +Y W FRE +LL Sbjct: 333 FIYAWLHDSFREELRKLL 350 >gi|11545887 neuropeptide FF receptor 1 [Homo sapiens] Length = 430 Score = 99.4 bits (246), Expect = 5e-21 Identities = 85/345 (24%), Positives = 146/345 (42%), Gaps = 41/345 (11%) Query: 4 NSTSLEAYTYLLLNTSNASDSGSTQLPAPLRISLAIVMLLMTVVGFLGNTVVCIIVYQRP 63 N T+ EA +N + S Q +P+ + L+ ++ +GNT+VC IV + Sbjct: 18 NGTNTEATP-----ATNLTFSSYYQHTSPVAAMFIVAYALIFLLCMVGNTLVCFIVLKNR 72 Query: 64 AMRSAINLLLATLAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFFVLEGVA 123 M + N+ + LA SD+++ + CMP T V + W F + C++S + V V Sbjct: 73 HMHTVTNMFILNLAVSDLLVGIFCMPTTLVDNLITGWPFDNATCKMSGLVQGMSVSASVF 132 Query: 124 ILLIISVDRFLIIVQR-QDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVE------VP 176 L+ I+V+RF IV ++KL R+A V IAV W L+ I PS T+ V Sbjct: 133 TLVAIAVERFRCIVHPFREKLTLRKALVTIAVIWALALLIMCPSAVTLTVTREEHHFMVD 192 Query: 177 AR-----APQCVLGYTELPADRAYVVTLVVAVFFAPFGVMLCAYMCILNTVRKNAVRVHN 231 AR C + E R Y L ++ AP +++ Y I + + Sbjct: 193 ARNRSYPLYSCWEAWPEKGMRRVYTTVLFSHIYLAPLALIVVMYARIARKLCQAPGPAPG 252 Query: 232 QSDSLDLRQLTRAGLRRLQRQQQVSVDLSFKTKAFTTILILFVGFSLCWLPHSVYSLLSV 291 ++ D R R + + ++++ + F+L WLP +++LL + Sbjct: 253 GEEAADPRASRR------------------RARVVHMLVMVALFFTLSWLP--LWALLLL 292 Query: 292 FSQRFYCGSSFYATSTCVL----WLSYLKSVFNPIVYCWRIKKFR 332 + + WL++ S NPI+Y + + FR Sbjct: 293 IDYGQLSAPQLHLVTVYAFPFAHWLAFFNSSANPIIYGYFNENFR 337 >gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] Length = 520 Score = 99.0 bits (245), Expect = 6e-21 Identities = 102/385 (26%), Positives = 169/385 (43%), Gaps = 43/385 (11%) Query: 4 NSTSLEAYTYLLLNTS----NASDSGST--QLPAPLRISLAIVMLLMTVVGFLGNTVVCI 57 ++TS A+ L N + N + S ST QL IS+ +V+ + +GN +V + Sbjct: 9 HNTSAPAHWGELKNANFTGPNQTSSNSTLPQLDITRAISVGLVLGAFILFAIVGNILVIL 68 Query: 58 IVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAVTLITVRWHFGDHFCRLSATLYWFF 117 V +R+ N + LA +D++LS +PF+A + W G FC + A + Sbjct: 69 SVACNRHLRTPTNYFIVNLAMADLLLSFTVLPFSAALEVLGYWVLGRIFCDIWAAVDVLC 128 Query: 118 VLEGVAILLIISVDRFLII---VQRQDKLNPRRAKVIIAVSWVLSFCIAGPSLTGWTLVE 174 + L IS+DR++ + +Q + R+A + + WVLS I+ L GW + Sbjct: 129 CTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILALLSVWVLSTVISIGPLLGW---K 185 Query: 175 VPARAPQCVLGYTELPADRAYVVTLVVAVFFAPFGVMLCAY------------------M 216 PA G TE P Y + + F+ P V+L Y M Sbjct: 186 EPAPNDDKECGVTEEP---FYALFSSLGSFYIPLAVILVMYCRVYIVAKRTTKNLEAGVM 242 Query: 217 CILNTVRKNAVRVHNQSDSLDLRQLTRAGLRRLQRQQQVSVDL---SFKTKAFTTILILF 273 ++ ++ +R+H+++ D T+A + + ++V L S + KA T+ I+ Sbjct: 243 KEMSNSKELTLRIHSKNFHEDTLSSTKA--KGHNPRSSIAVKLFKFSREKKAAKTLGIVV 300 Query: 274 VGFSLCWLPHSV-YSLLSVFSQRFYCGSSFYATSTCVLWLSYLKSVFNPIVYCWRIKKFR 332 F LCWLP + L S+FS + F V WL Y S NPI+Y K+F+ Sbjct: 301 GMFILCWLPFFIALPLGSLFSTLKPPDAVF----KVVFWLGYFNSCLNPIIYPCSSKEFK 356 Query: 333 EACIELLPQTFQILPKVPERIRRRI 357 A + +L + + R RRR+ Sbjct: 357 RAFVRILGCQCRGRGRRRRRRRRRL 381 >gi|197085610 histamine receptor H2 isoform 1 [Homo sapiens] Length = 397 Score = 98.6 bits (244), Expect = 8e-21 Identities = 70/305 (22%), Positives = 132/305 (43%), Gaps = 32/305 (10%) Query: 34 RISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAV 93 +I++ +V+ ++ ++ GN VVC+ V +R+ N + +LA +D++L L +PF+A+ Sbjct: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAI 77 Query: 94 TLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLII---VQRQDKLNPRRAKV 150 ++ +W FG FC + +L + L +IS+DR+ + ++ + P R + Sbjct: 78 YQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAI 137 Query: 151 IIAVSWVLSFCIAGPSL-TGWTLVEVPARAPQCVLGYTELPADRAYVVTLVVAVFFAPFG 209 + + WV+S ++ S+ GW ++ ++ + Y + + F+ P Sbjct: 138 SLVLIWVISITLSFLSIHLGWNSRNETSKGNH-TTSKCKVQVNEVYGLVDGLVTFYLPLL 196 Query: 210 VMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRAGLRRLQRQQQVSVDLSFKTKAFTTI 269 +M Y I R A R+++ + A +R + KA T+ Sbjct: 197 IMCITYYRIFKVARDQAKRINH------ISSWKAATIR--------------EHKATVTL 236 Query: 270 LILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFY--ATSTCVLWLSYLKSVFNPIVYCWR 327 + F +CW P+ + F R G VLWL Y S NPI+Y Sbjct: 237 AAVMGAFIICWFPY-----FTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAAL 291 Query: 328 IKKFR 332 + FR Sbjct: 292 NRDFR 296 >gi|13435405 histamine receptor H2 isoform 2 [Homo sapiens] Length = 359 Score = 98.6 bits (244), Expect = 8e-21 Identities = 70/305 (22%), Positives = 132/305 (43%), Gaps = 32/305 (10%) Query: 34 RISLAIVMLLMTVVGFLGNTVVCIIVYQRPAMRSAINLLLATLAFSDIMLSLCCMPFTAV 93 +I++ +V+ ++ ++ GN VVC+ V +R+ N + +LA +D++L L +PF+A+ Sbjct: 18 KITITVVLAVLILITVAGNVVVCLAVGLNRRLRNLTNCFIVSLAITDLLLGLLVLPFSAI 77 Query: 94 TLITVRWHFGDHFCRLSATLYWFFVLEGVAILLIISVDRFLII---VQRQDKLNPRRAKV 150 ++ +W FG FC + +L + L +IS+DR+ + ++ + P R + Sbjct: 78 YQLSCKWSFGKVFCNIYTSLDVMLCTASILNLFMISLDRYCAVMDPLRYPVLVTPVRVAI 137 Query: 151 IIAVSWVLSFCIAGPSL-TGWTLVEVPARAPQCVLGYTELPADRAYVVTLVVAVFFAPFG 209 + + WV+S ++ S+ GW ++ ++ + Y + + F+ P Sbjct: 138 SLVLIWVISITLSFLSIHLGWNSRNETSKGNH-TTSKCKVQVNEVYGLVDGLVTFYLPLL 196 Query: 210 VMLCAYMCILNTVRKNAVRVHNQSDSLDLRQLTRAGLRRLQRQQQVSVDLSFKTKAFTTI 269 +M Y I R A R+++ + A +R + KA T+ Sbjct: 197 IMCITYYRIFKVARDQAKRINH------ISSWKAATIR--------------EHKATVTL 236 Query: 270 LILFVGFSLCWLPHSVYSLLSVFSQRFYCGSSFY--ATSTCVLWLSYLKSVFNPIVYCWR 327 + F +CW P+ + F R G VLWL Y S NPI+Y Sbjct: 237 AAVMGAFIICWFPY-----FTAFVYRGLRGDDAINEVLEAIVLWLGYANSALNPILYAAL 291 Query: 328 IKKFR 332 + FR Sbjct: 292 NRDFR 296 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.331 0.139 0.436 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,360,589 Number of Sequences: 37866 Number of extensions: 489369 Number of successful extensions: 2765 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 360 Number of HSP's successfully gapped in prelim test: 227 Number of HSP's that attempted gapping in prelim test: 1656 Number of HSP's gapped (non-prelim): 786 length of query: 372 length of database: 18,247,518 effective HSP length: 104 effective length of query: 268 effective length of database: 14,309,454 effective search space: 3834933672 effective search space used: 3834933672 T: 11 A: 40 X1: 15 ( 7.2 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 40 (21.9 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.