MCPH1 2524

Name: MCPH1	Sequence: fasta or formatted (835aa)		NCBI GI: 122891872
Description: microcephalin		Referenced in: Additional Brain Proteins
Composition: Amino acid Percentage Count Longest homopolymer A alanine 5.0 42 2 C cysteine 3.1 26 2 D aspartate 4.9 41 3 E glutamate 7.4 62 2 F phenylalanine 3.1 26 1 G glycine 5.6 47 2 H histidine 3.0 25 2 I isoleucine 3.8 32 1 K lysine 8.7 73 3 L leucine 8.6 72 2 M methionine 1.9 16 1 N asparagine 4.2 35 2 P proline 5.7 48 2 Q glutamine 3.8 32 2 R arginine 4.8 40 2 S serine 12.1 101 3 T threonine 5.6 47 3 V valine 5.5 46 2 W tryptophan 1.0 8 1 Y tyrosine 1.9 16 1			Comparative genomics: Search single species RefSeq proteins at NCBI H. sapiens M. musculus D. rerio C. intestinalis S. purpuratus D. melanogaster C. elegans A. thaliana S. cerevisiae E. coli W3110 A. pernix K1 Search summary Figure data Additional searches of RefSeq proteins at NCBI All Eukaryotes Bacteria Archaea Viruses Primates Mammals Vertebrates
Related human proteins: Protein Relative score Description Self-match 1.000 microcephalin TOPBP1 0.021 topoisomerase (DNA) II binding protein 1 BRCA1 0.013 breast cancer 1, early onset isoform 2 BRCA1 0.013 breast cancer 1, early onset isoform 4 BRCA1 0.013 breast cancer 1, early onset isoform 3 BRCA1 0.013 breast cancer 1, early onset isoform 1 ANKRD32 0.012 ankyrin repeat domain 32 BARD1 0.011 BRCA1 associated RING domain 1 SRRM2 0.010 splicing coactivator subunit SRm300 ZBTB5 0.010 zinc finger and BTB domain containing 5 BRCA1 0.010 breast cancer 1, early onset isoform 5 ARHGAP24 0.010 Rho GTPase activating protein 24 isoform 3 ARHGAP24 0.010 Rho GTPase activating protein 24 isoform 2 ARHGAP24 0.010 Rho GTPase activating protein 24 isoform 1 KIAA1853 0.008 KIAA1853 protein MDC1 0.008 mediator of DNA-damage checkpoint 1 SFRS2IP 0.007 splicing factor, arginine/serine-rich 2, interactin... LMNB1 0.007 lamin B1 RIMS1 0.007 regulating synaptic membrane exocytosis 1 MTMR3 0.006 myotubularin-related protein 3 isoform c GCC2 0.006 GRIP and coiled-coil domain-containing 2 GOLGB1 0.005 golgi autoantigen, golgin subfamily b, macrogolgin ... THOC2 0.005 THO complex 2 RICTOR 0.005 rapamycin-insensitive companion of mTOR FAM21A 0.005 hypothetical protein LOC387680 FAM21B 0.005 hypothetical protein LOC55747 CLSPN 0.005 claspin PHRF1 0.005 PHD and ring finger domains 1 CDKL2 0.005 cyclin-dependent kinase-like 2 KIF20B 0.005 M-phase phosphoprotein 1 Human BLASTP results (used to prepare the table)

Gene descriptions are from NCBI RefSeq. Search results were obtained with NCBI BLAST and RefSeq entries. When identical proteins are present, the self-match may not be listed first in BLASTP output. In such cases, the table above has been reordered to place it first.

See About the Figures for the scoring system used in the figure above right. The same scoring system was used in the table of BLASTP results.