Guide to the Human Genome
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Search of human proteins with 28603852

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|28603852 Yip1 domain family, member 6 [Homo sapiens]
         (236 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|28603852 Yip1 domain family, member 6 [Homo sapiens]               471   e-133
gi|14150076 Yip1 domain family, member 4 [Homo sapiens]                67   1e-11
gi|148664222 Yip1 domain family, member 7 [Homo sapiens]               44   1e-04
gi|68226422 Yip1 domain family, member 5 [Homo sapiens]                42   4e-04
gi|32401427 Yip1 domain family, member 5 [Homo sapiens]                42   4e-04
gi|4759050 ribosomal protein S6 kinase, 90kDa, polypeptide 3 [Ho...    29   3.1  
gi|145207958 transmembrane protein 16G isoform NGEP long [Homo s...    28   5.3  
gi|13128976 Yip1 domain family, member 2 [Homo sapiens]                28   5.3  
gi|27502417 CD46 antigen, complement regulatory protein isoform ...    28   9.0  
gi|27502411 CD46 antigen, complement regulatory protein isoform ...    28   9.0  
gi|24432108 CD46 antigen, complement regulatory protein isoform ...    28   9.0  
gi|27502427 CD46 antigen, complement regulatory protein isoform ...    28   9.0  
gi|27502425 CD46 antigen, complement regulatory protein isoform ...    28   9.0  
gi|27502423 CD46 antigen, complement regulatory protein isoform ...    28   9.0  
gi|110618256 trace amine associated receptor 9 [Homo sapiens]          28   9.0  

>gi|28603852 Yip1 domain family, member 6 [Homo sapiens]
          Length = 236

 Score =  471 bits (1212), Expect = e-133
 Identities = 236/236 (100%), Positives = 236/236 (100%)

Query: 1   MAEAEESPGDPGTASPRPLFAGLSDISISQDIPVEGEITIPMRSRIREFDSSTLNESVRN 60
           MAEAEESPGDPGTASPRPLFAGLSDISISQDIPVEGEITIPMRSRIREFDSSTLNESVRN
Sbjct: 1   MAEAEESPGDPGTASPRPLFAGLSDISISQDIPVEGEITIPMRSRIREFDSSTLNESVRN 60

Query: 61  TIMRDLKAVGKKFMHVLYPRKSNTLLRDWDLWGPLILCVTLALMLQRDSADSEKDGGPQF 120
           TIMRDLKAVGKKFMHVLYPRKSNTLLRDWDLWGPLILCVTLALMLQRDSADSEKDGGPQF
Sbjct: 61  TIMRDLKAVGKKFMHVLYPRKSNTLLRDWDLWGPLILCVTLALMLQRDSADSEKDGGPQF 120

Query: 121 AEVFVIVWFGAVTITLNSKLLGGNISFFQSLCVLGYCILPLTVAMLICRLVLLADPGPVN 180
           AEVFVIVWFGAVTITLNSKLLGGNISFFQSLCVLGYCILPLTVAMLICRLVLLADPGPVN
Sbjct: 121 AEVFVIVWFGAVTITLNSKLLGGNISFFQSLCVLGYCILPLTVAMLICRLVLLADPGPVN 180

Query: 181 FMVRLFVVIVMFAWSIVASTALLADSQPPNRRALAVYPVFLFYFVISWMILTFTPQ 236
           FMVRLFVVIVMFAWSIVASTALLADSQPPNRRALAVYPVFLFYFVISWMILTFTPQ
Sbjct: 181 FMVRLFVVIVMFAWSIVASTALLADSQPPNRRALAVYPVFLFYFVISWMILTFTPQ 236


>gi|14150076 Yip1 domain family, member 4 [Homo sapiens]
          Length = 244

 Score = 67.0 bits (162), Expect = 1e-11
 Identities = 51/182 (28%), Positives = 92/182 (50%), Gaps = 20/182 (10%)

Query: 48  EFDSSTLNESVRNTIMRDLKAVGKKFMHVLYPRKS----NTLLRDW-DLWGPLILCVTLA 102
           E D    N+ +   +  DLK +  K   VL P  S      ++RD  D WGPL + +  +
Sbjct: 67  EDDDPEDNKPLLEELDIDLKDIYYKIRCVLMPMPSLGFNRQVVRDNPDFWGPLAVVLFFS 126

Query: 103 LMLQRDSADSEKDGGPQFAEVFVIVW-FGAVTITLNSKLLGGNISFFQSLCVLGYCILPL 161
           ++           G  +     + +W FG++TI L +++LGG +++ Q L V+GY +LPL
Sbjct: 127 MI--------SLYGQFRVVSWIITIWIFGSLTIFLLARVLGGEVAYGQVLGVIGYSLLPL 178

Query: 162 TVAMLICRLVLLADPGPVNFMVRLFVVIVMFAWSIVASTALLADSQPPNRRALAVYPVFL 221
            V   +  L+++     V+ +++LF V     W+  ++ +LL   +   ++ L +YP+FL
Sbjct: 179 IVIAPV--LLVVGSFEVVSTLIKLFGVF----WAAYSAASLLVGEEFKTKKPLLIYPIFL 232

Query: 222 FY 223
            Y
Sbjct: 233 LY 234


>gi|148664222 Yip1 domain family, member 7 [Homo sapiens]
          Length = 280

 Score = 43.9 bits (102), Expect = 1e-04
 Identities = 40/159 (25%), Positives = 70/159 (44%), Gaps = 17/159 (10%)

Query: 69  VGKKFMHVLYPRK--SNTLLRDWDLWGPLILCVTLALMLQRDSADSEKDGGPQFAEVFVI 126
           + +K + VL P K    +++ + DL GP++ CV L   L          G  QF  V+ +
Sbjct: 126 IWQKTLTVLNPMKPVDGSIMNETDLTGPILFCVALGATLL-------LAGKVQFGYVYGM 178

Query: 127 VWFGAVTI-TLNSKLLGGNISFFQSLCVLGYCILPLTVAMLICRLVLLADPGPVNFMVRL 185
              G + I  L + +    +S+     VLGYC+LP+ V +  C +        +  +  +
Sbjct: 179 SAIGCLVIHALLNLMSSSGVSYGCVASVLGYCLLPM-VILSGCAMFF-----SLQGIFGI 232

Query: 186 FVVIVMFAW-SIVASTALLADSQPPNRRALAVYPVFLFY 223
              +V+  W S+ AS   +A      ++ L  YP  + Y
Sbjct: 233 MSSLVIIGWCSLSASKIFIAALHMEGQQLLVAYPCAILY 271


>gi|68226422 Yip1 domain family, member 5 [Homo sapiens]
          Length = 257

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 19/164 (11%)

Query: 69  VGKKFMHVLYPRK--SNTLLRDWDLWGPLILCVTLALMLQRDSADSEKDGGPQFAEVFVI 126
           + +K + VL+P K    +++ + DL GP++ C+     L          G  QF  V+ I
Sbjct: 103 IWQKTLTVLHPLKVADGSIMNETDLAGPMVFCLAFGATLLLA-------GKIQFGYVYGI 155

Query: 127 VWFGAVTI--TLNSKLLGGNISFFQSLCVLGYCILPLTVAMLICRLVLLADPGPVNFMVR 184
              G + +   LN   + G +SF     VLGYC+LP+   +L    V+ +  G    MV 
Sbjct: 156 SAIGCLGMFCLLNLMSMTG-VSFGCVASVLGYCLLPM--ILLSSFAVIFSLQG----MVG 208

Query: 185 LFVVIVMFAW-SIVASTALLADSQPPNRRALAVYPVFLFYFVIS 227
           + +   +  W S  AS   ++      ++ L  YP  L Y V +
Sbjct: 209 IILTAGIIGWCSFSASKIFISALAMEGQQLLVAYPCALLYGVFA 252


>gi|32401427 Yip1 domain family, member 5 [Homo sapiens]
          Length = 257

 Score = 42.4 bits (98), Expect = 4e-04
 Identities = 44/164 (26%), Positives = 73/164 (44%), Gaps = 19/164 (11%)

Query: 69  VGKKFMHVLYPRK--SNTLLRDWDLWGPLILCVTLALMLQRDSADSEKDGGPQFAEVFVI 126
           + +K + VL+P K    +++ + DL GP++ C+     L          G  QF  V+ I
Sbjct: 103 IWQKTLTVLHPLKVADGSIMNETDLAGPMVFCLAFGATLLLA-------GKIQFGYVYGI 155

Query: 127 VWFGAVTI--TLNSKLLGGNISFFQSLCVLGYCILPLTVAMLICRLVLLADPGPVNFMVR 184
              G + +   LN   + G +SF     VLGYC+LP+   +L    V+ +  G    MV 
Sbjct: 156 SAIGCLGMFCLLNLMSMTG-VSFGCVASVLGYCLLPM--ILLSSFAVIFSLQG----MVG 208

Query: 185 LFVVIVMFAW-SIVASTALLADSQPPNRRALAVYPVFLFYFVIS 227
           + +   +  W S  AS   ++      ++ L  YP  L Y V +
Sbjct: 209 IILTAGIIGWCSFSASKIFISALAMEGQQLLVAYPCALLYGVFA 252


>gi|4759050 ribosomal protein S6 kinase, 90kDa, polypeptide 3 [Homo
           sapiens]
          Length = 740

 Score = 29.3 bits (64), Expect = 3.1
 Identities = 13/50 (26%), Positives = 29/50 (58%)

Query: 5   EESPGDPGTASPRPLFAGLSDISISQDIPVEGEITIPMRSRIREFDSSTL 54
           ++SPG P +A+   LF G S ++I+ D   +   T+ + S +++   +++
Sbjct: 367 KDSPGIPPSANAHQLFRGFSFVAITSDDESQAMQTVGVHSIVQQLHRNSI 416


>gi|145207958 transmembrane protein 16G isoform NGEP long [Homo
           sapiens]
          Length = 933

 Score = 28.5 bits (62), Expect = 5.3
 Identities = 23/77 (29%), Positives = 33/77 (42%), Gaps = 3/77 (3%)

Query: 16  PRPLFAGLSDISISQDIPVEGEITIPMRSRIREF--DSSTLNESVRNTIMRDLKAV-GKK 72
           PRP FA  + ++    I  E E   P RSR R     S  +   V   +M  +  +  + 
Sbjct: 464 PRPQFAASAPMTAPNPITGEDEPYFPERSRARRMLAGSVVIVVMVAVVVMCLVSIILYRA 523

Query: 73  FMHVLYPRKSNTLLRDW 89
            M ++  R  NTLL  W
Sbjct: 524 IMAIVVSRSGNTLLAAW 540


>gi|13128976 Yip1 domain family, member 2 [Homo sapiens]
          Length = 316

 Score = 28.5 bits (62), Expect = 5.3
 Identities = 29/121 (23%), Positives = 47/121 (38%), Gaps = 30/121 (24%)

Query: 77  LYPRKSNTLLRDW-----DLWGPLILCVTLALMLQ---------RDSADSEKDGGPQFAE 122
           L PR  +  +R       DL+GP  +C TLA +L              D      PQF +
Sbjct: 102 LLPRPGHNFVRHHLRNRPDLYGPFWICATLAFVLAVTGNLTLVLAQRRDPSIHYSPQFHK 161

Query: 123 VFV-------------IVWFGAVTITLNSKLLGGNISFFQSLCVLGYCI---LPLTVAML 166
           V V             +  +G +      +   G  +F +++C+ GY +   +P+ V  L
Sbjct: 162 VTVAGISIYCYAWLVPLALWGFLRWRKGVQERMGPYTFLETVCIYGYSLFVFIPMVVLWL 221

Query: 167 I 167
           I
Sbjct: 222 I 222


>gi|27502417 CD46 antigen, complement regulatory protein isoform 10
           precursor [Homo sapiens]
          Length = 370

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 15/55 (27%), Positives = 23/55 (41%), Gaps = 11/55 (20%)

Query: 78  YPRKSNTLLRDWDLW-----------GPLILCVTLALMLQRDSADSEKDGGPQFA 121
           YP+    +L   D+W           G  ++CV     LQR     + DGG ++A
Sbjct: 302 YPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKKGKADGGAEYA 356


>gi|27502411 CD46 antigen, complement regulatory protein isoform 6
           precursor [Homo sapiens]
          Length = 369

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 15/55 (27%), Positives = 23/55 (41%), Gaps = 11/55 (20%)

Query: 78  YPRKSNTLLRDWDLW-----------GPLILCVTLALMLQRDSADSEKDGGPQFA 121
           YP+    +L   D+W           G  ++CV     LQR     + DGG ++A
Sbjct: 301 YPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKKGKADGGAEYA 355


>gi|24432108 CD46 antigen, complement regulatory protein isoform 4
           precursor [Homo sapiens]
          Length = 384

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 15/55 (27%), Positives = 23/55 (41%), Gaps = 11/55 (20%)

Query: 78  YPRKSNTLLRDWDLW-----------GPLILCVTLALMLQRDSADSEKDGGPQFA 121
           YP+    +L   D+W           G  ++CV     LQR     + DGG ++A
Sbjct: 316 YPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKKGKADGGAEYA 370


>gi|27502427 CD46 antigen, complement regulatory protein isoform 12
           precursor [Homo sapiens]
          Length = 355

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 15/55 (27%), Positives = 23/55 (41%), Gaps = 11/55 (20%)

Query: 78  YPRKSNTLLRDWDLW-----------GPLILCVTLALMLQRDSADSEKDGGPQFA 121
           YP+    +L   D+W           G  ++CV     LQR     + DGG ++A
Sbjct: 287 YPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKKGKADGGAEYA 341


>gi|27502425 CD46 antigen, complement regulatory protein isoform 8
           precursor [Homo sapiens]
          Length = 385

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 15/55 (27%), Positives = 23/55 (41%), Gaps = 11/55 (20%)

Query: 78  YPRKSNTLLRDWDLW-----------GPLILCVTLALMLQRDSADSEKDGGPQFA 121
           YP+    +L   D+W           G  ++CV     LQR     + DGG ++A
Sbjct: 317 YPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKKGKADGGAEYA 371


>gi|27502423 CD46 antigen, complement regulatory protein isoform 2
           precursor [Homo sapiens]
          Length = 399

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 15/55 (27%), Positives = 23/55 (41%), Gaps = 11/55 (20%)

Query: 78  YPRKSNTLLRDWDLW-----------GPLILCVTLALMLQRDSADSEKDGGPQFA 121
           YP+    +L   D+W           G  ++CV     LQR     + DGG ++A
Sbjct: 331 YPKPEEGILDSLDVWVIAVIVIAIVVGVAVICVVPYRYLQRRKKKGKADGGAEYA 385


>gi|110618256 trace amine associated receptor 9 [Homo sapiens]
          Length = 348

 Score = 27.7 bits (60), Expect = 9.0
 Identities = 27/119 (22%), Positives = 48/119 (40%), Gaps = 14/119 (11%)

Query: 125 VIVWFGAVTITLNSKLLGGNISFFQSLCV----LGYCILPLTVA-MLICRLVLLADPGPV 179
           V+ WF +VT + +    G N    + L V    +G C  PL    +L+C L+       +
Sbjct: 154 VLSWFFSVTYSFSIFYTGANEEGIEELVVALTCVGGCQAPLNQNWVLLCFLLFFIPNVAM 213

Query: 180 NFMVRLFVVIVMFAWSIVASTALLADSQPPN---------RRALAVYPVFLFYFVISWM 229
            F+     ++       + STA  A S   +         R+A     + +  F++SW+
Sbjct: 214 VFIYSKIFLVAKHQARKIESTASQAQSSSESYKERVAKRERKAAKTLGIAMAAFLVSWL 272


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.432 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,953,341
Number of Sequences: 37866
Number of extensions: 357678
Number of successful extensions: 1111
Number of sequences better than 10.0: 15
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 12
Number of HSP's that attempted gapping in prelim test: 1104
Number of HSP's gapped (non-prelim): 15
length of query: 236
length of database: 18,247,518
effective HSP length: 99
effective length of query: 137
effective length of database: 14,498,784
effective search space: 1986333408
effective search space used: 1986333408
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 60 (27.7 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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