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Search of human proteins with 27735129
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27735129 hypothetical protein LOC148345 [Homo sapiens]
(656 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27735129 hypothetical protein LOC148345 [Homo sapiens] 1325 0.0
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 74 4e-13
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 70 8e-12
gi|163965366 nascent polypeptide-associated complex alpha subuni... 70 8e-12
gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo ... 68 2e-11
gi|189181724 proteoglycan 4 isoform D [Homo sapiens] 66 9e-11
gi|189181722 proteoglycan 4 isoform C [Homo sapiens] 66 9e-11
gi|189181720 proteoglycan 4 isoform B [Homo sapiens] 66 9e-11
gi|67190163 proteoglycan 4 isoform A [Homo sapiens] 66 9e-11
gi|149773456 hypothetical protein LOC643314 [Homo sapiens] 66 1e-10
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 65 2e-10
gi|47132519 Ras association and pleckstrin homology domains 1 is... 65 2e-10
gi|163914392 glioma tumor suppressor candidate region gene 1 [Ho... 62 1e-09
gi|110832843 TBP-associated factor 4 [Homo sapiens] 62 2e-09
gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens] 61 3e-09
gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo sa... 61 4e-09
gi|116284392 mucin 2 precursor [Homo sapiens] 59 1e-08
gi|154146199 sal-like 3 [Homo sapiens] 59 1e-08
gi|116256464 hypothetical protein LOC343990 [Homo sapiens] 59 1e-08
gi|41281612 zinc finger protein 828 [Homo sapiens] 59 2e-08
gi|122937496 WAS/WASL interacting protein family, member 3 [Homo... 59 2e-08
gi|146219843 Snf2-related CBP activator protein [Homo sapiens] 57 7e-08
gi|222352122 hypothetical protein LOC284297 [Homo sapiens] 55 3e-07
gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens] 54 5e-07
gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens] 54 5e-07
gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens] 54 5e-07
gi|85815829 SH3-domain binding protein 1 [Homo sapiens] 54 6e-07
gi|19924099 synapsin I isoform Ia [Homo sapiens] 53 8e-07
gi|110349719 titin isoform N2-A [Homo sapiens] 53 1e-06
gi|112421108 capicua homolog [Homo sapiens] 53 1e-06
>gi|27735129 hypothetical protein LOC148345 [Homo sapiens]
Length = 656
Score = 1325 bits (3428), Expect = 0.0
Identities = 656/656 (100%), Positives = 656/656 (100%)
Query: 1 MKCPMLRSRLGQESVHCGPMFIQVSRPLPLWRDNRQTPWLLSLRGELVASLEDASLMGLY 60
MKCPMLRSRLGQESVHCGPMFIQVSRPLPLWRDNRQTPWLLSLRGELVASLEDASLMGLY
Sbjct: 1 MKCPMLRSRLGQESVHCGPMFIQVSRPLPLWRDNRQTPWLLSLRGELVASLEDASLMGLY 60
Query: 61 VDMNATTVTVQSPRQGLLQRWEVSGGQQALPGVSFQPESEVLVHIPKQRLGLVKRGSYIE 120
VDMNATTVTVQSPRQGLLQRWEVSGGQQALPGVSFQPESEVLVHIPKQRLGLVKRGSYIE
Sbjct: 61 VDMNATTVTVQSPRQGLLQRWEVSGGQQALPGVSFQPESEVLVHIPKQRLGLVKRGSYIE 120
Query: 121 ETLSLRLLRVHQSNIFMVTENKDFVVVSIPAAGVLQVQRCQEVGGTPGTQAFYRVDLSLE 180
ETLSLRLLRVHQSNIFMVTENKDFVVVSIPAAGVLQVQRCQEVGGTPGTQAFYRVDLSLE
Sbjct: 121 ETLSLRLLRVHQSNIFMVTENKDFVVVSIPAAGVLQVQRCQEVGGTPGTQAFYRVDLSLE 180
Query: 181 FAEMAAPVLWTVESFFQCVGSGTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWA 240
FAEMAAPVLWTVESFFQCVGSGTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWA
Sbjct: 181 FAEMAAPVLWTVESFFQCVGSGTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWA 240
Query: 241 AGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPP 300
AGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPP
Sbjct: 241 AGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPP 300
Query: 301 GEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPER 360
GEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPER
Sbjct: 301 GEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPER 360
Query: 361 PESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEE 420
PESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEE
Sbjct: 361 PESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEE 420
Query: 421 FQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSE 480
FQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSE
Sbjct: 421 FQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSE 480
Query: 481 PSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPL 540
PSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPL
Sbjct: 481 PSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPL 540
Query: 541 PPEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTLSLWAPT 600
PPEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTLSLWAPT
Sbjct: 541 PPEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTLSLWAPT 600
Query: 601 GVLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPPELQDSVEGLSERPSR 656
GVLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPPELQDSVEGLSERPSR
Sbjct: 601 GVLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPPELQDSVEGLSERPSR 656
>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapiens]
Length = 1124
Score = 73.9 bits (180), Expect = 4e-13
Identities = 114/408 (27%), Positives = 146/408 (35%), Gaps = 61/408 (14%)
Query: 203 TEPPASTAA--LRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDA 260
++ P S AA L+ PSPP+ P +P A PP A + A P Q S S +
Sbjct: 693 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPL--AAPPLQVPPSPPASPPMSPS 750
Query: 261 LAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIP--GHPTPPATLPSE 318
P L A P + + + LP A+ PQ PP A P P+PPA+ P +
Sbjct: 751 ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQ 810
Query: 319 ---------PVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPR--PERPESLLVS 367
P+ + P + PVL P L +P S A SP+ APR P VS
Sbjct: 811 APFSPSASLPMSPLATPPPQAPPVLAA-PLLQVPPSPPA-SPTLQAPRRPPTPGPDTSVS 868
Query: 368 GPSVTLTEGLGTVRPEQDPAKSPGSPLL---LRGLSSGDVAAPEPIMGEPGQASEEFQPL 424
GP +TL G P P++SP S L L G SS + PE + G
Sbjct: 869 GPRLTLALAPG---PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAAS 925
Query: 425 ARPWRATLAAEELVSHRSPGEPQ--ETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPS 482
P A R P P G + P TGPG A G +
Sbjct: 926 PPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG----SADGLCTI------ 975
Query: 483 QDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTG-----MPRVRLAAPLAVLPM 537
+ EGP ++ P P PS S G G R A L LP+
Sbjct: 976 YETEGP--------ESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPL 1027
Query: 538 EPLPPEPVR---PAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGV 582
L V+ LL A G + G P G E GV
Sbjct: 1028 GALQASVVQHLLSRTLLLAAAEGAAG--------GSGGGPGGAEGGGV 1067
Score = 70.5 bits (171), Expect = 5e-12
Identities = 119/483 (24%), Positives = 159/483 (32%), Gaps = 78/483 (16%)
Query: 200 GSGTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSD 259
G+ PA+ A TP PP G PP V PAA + AAG ++ L+
Sbjct: 11 GAAARTPAARAPGLLTPRPP--GSPRPPPPVTPAALRVLGAAGAVGRKPLAE-------- 60
Query: 260 ALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEP 319
G+G R G T ++ A R P GE P T P + S
Sbjct: 61 --RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP- 117
Query: 320 VEGVQASPWRPRPV--------------------LPTHPALTLPVSSDASSPSPPAPRPE 359
G + RP P+ P AL+ D S P+P P P
Sbjct: 118 --GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175
Query: 360 RPESLLVSGPSVTLTEGLGTVRPE---QDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQ 416
+G V L + RP + P KS S A P G Q
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQ 235
Query: 417 ------ASEEFQPLARPWRATLAAEELVSHRSPGEP-QETCSGTEVERPRQTGPGLPREG 469
S PL+ P R+ +A + R+P P Q G + RP Q P PR+
Sbjct: 236 RPASRSLSSSATPLSSPARSGPSARG--TPRAPAHPSQPKPKGLQALRPPQVTP--PRKD 291
Query: 470 ARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLA 529
A + SS P P+ T + P V PD +A T +P
Sbjct: 292 AAPALGPLSSSP---------LATPSPSGTKARP-VPPPDNAA--------TPLPATLPP 333
Query: 530 APLAVLPMEPLPPEPVRPAALLTPEASSVGGPDQARYLESAPGW---------PVGQEEW 580
+P P+ PP P P +L T + P QA + P P Q
Sbjct: 334 SPPLATPLPLAPPSPSAPPSLQTLPSPPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPH 393
Query: 581 GVAHTS--SPPSTQTLSLWAPTGVLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESH 638
+ S +PPS LS T L ++ + F Q LT P+ S
Sbjct: 394 SLTSPSLQAPPSPLALSSLQATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPD 453
Query: 639 RPP 641
PP
Sbjct: 454 SPP 456
Score = 67.8 bits (164), Expect = 3e-11
Identities = 132/509 (25%), Positives = 170/509 (33%), Gaps = 67/509 (13%)
Query: 182 AEMAAPVLWTVESFFQCVGSGTEPPASTAALRTTPSPPSPGPETPPA-------GVPPAA 234
A + P L T C P +T T S +P P+ PPA G+P
Sbjct: 551 APLTTPHLETPPCPAPCPLQAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPP 610
Query: 235 SSQVWAAGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQR 294
S + P A L+ L P A L P L T P Q ++ ++QA
Sbjct: 611 LSPLATPPPQAPPXLALPPLQAPPSPPASPPLSP-LATPSP----QAPNALAVHLLQAPF 665
Query: 295 GPQP-PPGEAGI--PGHP--TPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDAS 349
P P PP +A P P +P AT PS+ + A P + P P P ++ +
Sbjct: 666 SPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ 725
Query: 350 SP----SPPAPRPERPESLLVSGPSVT-------LTEGLGTVRPEQDPAKSPGSPLLLRG 398
+P +PP P P + PS T L P PA P SPL
Sbjct: 726 APPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPP 785
Query: 399 LSSGDV-------AAPEPIMGEPGQ------ASEEFQPLARP---WRATLAAEELVSHRS 442
+ A P P PGQ AS PLA P LAA L +
Sbjct: 786 PQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL---QV 842
Query: 443 PGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFST 502
P P + + RP GP G R + L+ P P ++ A S+
Sbjct: 843 PPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSS 902
Query: 503 PSVRQPDPSAWLSSGPE----LTGMPRVRLAA-PLAVLPMEPLPPEPVR---PAALLTPE 554
+ P+ SGPE + P LAA A P PP R A L P
Sbjct: 903 SATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPP 962
Query: 555 ASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTLSLWAPTGVLLPSLVELEYPF 614
A+ G D + G G P T A G S P
Sbjct: 963 ATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGKAAAGAGAGASS----RSPK 1018
Query: 615 QAGRG--------ASLQQELTEPTLALSA 635
QA G AS+ Q L TL L+A
Sbjct: 1019 QARLGELPLGALQASVVQHLLSRTLLLAA 1047
Score = 66.2 bits (160), Expect = 9e-11
Identities = 108/462 (23%), Positives = 163/462 (35%), Gaps = 42/462 (9%)
Query: 203 TEPPASTAALRTTPSPPSPGPETPPAGV----PPAASSQVWAAGPAAQEWLSRDLLHRPS 258
+ P S + R TP P+ + P G+ PP + A PA LS L PS
Sbjct: 250 SSPARSGPSARGTPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGP-LSSSPLATPS 308
Query: 259 DALAKKGLGPFLQTAKPARRGQTSASILPRVVQ-----AQRGPQPPPGEAGIPGH---PT 310
+ K A+P +A+ LP + A P PP + P P+
Sbjct: 309 PSGTK---------ARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTLPS 359
Query: 311 PPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVS-SDASSPSPPAP--RPERPESLLVS 367
PPAT PS+ + P + P L T P + +P S + S +PP+P + +
Sbjct: 360 PPATPPSQAPPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLALSSLQATTSLG 419
Query: 368 GPSVTLTEGLGTVRPEQDPAK--SPGSPLLLRGLSSGDVAAPEPIMGEP---GQASEEFQ 422
P++ T T+ P Q A SP P S + AP + P S
Sbjct: 420 SPTLQATHSFLTMSPRQTQASLTSPSRPASTPP-DSPPLQAPLSLPASPPLQTSLSPAVS 478
Query: 423 PLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPS 482
PL+ P T+ + +S + PQ S + P +T L + ++ P
Sbjct: 479 PLSSP--LTIHPLQALSSLASHSPQAPLSSL-IMPPLETQSSLAPPSLQTPPASLTTPPL 535
Query: 483 QDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPP 542
+++ L A +TP + P A P P L P P P
Sbjct: 536 ENLPSLAPPPLQTASAPLTTPHLETPPCPA-----PCPLQAPPSPLTTPPPETPSSIATP 590
Query: 543 EPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTLSLWAPTGV 602
P P AL +P + P + P P + SPP++ LS A
Sbjct: 591 PPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSP 650
Query: 603 LLPSLVE---LEYPFQAGRGASLQQELTEPTLALSAESHRPP 641
P+ + L+ PF +Q + P + S PP
Sbjct: 651 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPP 692
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 69.7 bits (169), Expect = 8e-12
Identities = 120/451 (26%), Positives = 160/451 (35%), Gaps = 60/451 (13%)
Query: 200 GSGTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSD 259
G+ PA+ A TP PP G PP V PAA + AAG ++ L+
Sbjct: 11 GAAARTPAARAPGLLTPRPP--GSPRPPPPVTPAALRVLGAAGAVGRKPLAE-------- 60
Query: 260 ALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGP---QPPPGEAGIPGHP---TPPA 313
G+G R G T S P + +R P PG PG T P
Sbjct: 61 --RAGGIGGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPG 118
Query: 314 TLPSEPVE-GVQASPWRPRPV-LPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSV 371
L + + + + R + P AL+ D S P+P P P +G V
Sbjct: 119 PLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPAMARRSRAAGTEV 178
Query: 372 TLTEGLGTVRPE---QDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQ------ASEEFQ 422
L + RP + P KS S A P G Q S
Sbjct: 179 GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSAT 238
Query: 423 PLARPWRATLAAEELVSHRSPGEP-QETCSGTEVERPRQTGP----GLPREGARGHMDL- 476
PL+ P R+ +A + R+P P Q G + RP Q P P G L
Sbjct: 239 PLSSPARSGPSARG--TPRAPAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLA 296
Query: 477 --SSSEPSQDIEGPGLSILPARDAT---FSTPSVRQPD--------PSAWLSSGPELTGM 523
S S P P L LP+ AT +T S+ P PS LS P T
Sbjct: 297 TPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLS--PLATPP 354
Query: 524 PRVRLAAPLAVLPMEPLPP--EPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWG 581
P+ A L L P PP P+ P A +P+A + + S P P Q +
Sbjct: 355 PQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFS 414
Query: 582 ------VAHTSSPPSTQTLSLWAPTGVLLPS 606
V+ +++PPS SL AP + PS
Sbjct: 415 PPASPPVSPSATPPSQAPPSLAAPPLQVPPS 445
Score = 59.3 bits (142), Expect = 1e-08
Identities = 121/491 (24%), Positives = 163/491 (33%), Gaps = 74/491 (15%)
Query: 185 AAPVLWTVESFFQCVGSGTEPPASTA--ALRTTPSPPSPGPETPPAGVPPAASSQVWAAG 242
AAP L + S S + PP+ +A +L+T PSPP+ TPP+ + S A
Sbjct: 283 AAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPA----TPPSQATTSLGSPTLQA- 337
Query: 243 PAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGE 302
+ L P P A P + + ++ P + P PP
Sbjct: 338 -------THSFLPSP----------PLSPLATPPPQAPPALALPPL-----QAPPSPPAS 375
Query: 303 AGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTH----PALTLPVSSDASSPSPPAPRP 358
+ TP P+ + +P+ P P P P + PVS A+ PS P
Sbjct: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSL 435
Query: 359 ERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLR--------GLSSGDV-AAPEP 409
P + P + P Q P PL L L++ + A P P
Sbjct: 436 AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSP 495
Query: 410 IMGEPGQ------ASEEFQPLARP---WRATLAAEELVSHRSPGEPQETCSGTEVERPRQ 460
PGQ AS PLA P LAA L + P P + + RP
Sbjct: 496 PASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLL---QVPPSPPASPTLQAPRRPPT 552
Query: 461 TGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPE- 519
GP G R + L+ P P ++ A S+ + P+ SGPE
Sbjct: 553 PGPDTSVSGPRLTLALAPGPPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEG 612
Query: 520 ---LTGMPRVRLAA-PLAVLPMEPLPPEPVR---PAALLTPEASSVGGPDQARYLESAPG 572
+ P LAA A P PP R A L P A+ G D + G
Sbjct: 613 GAAASPPPDAELAACHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEG 672
Query: 573 WPVGQEEWGVAHTSSPPSTQTLSLWAPTGVLLPSLVELEYPFQAGRG--------ASLQQ 624
G P T A G S P QA G AS+ Q
Sbjct: 673 PESATPAPGALDPGPSPGTSGGKAAAGAGAGASS----RSPKQARLGELPLGALQASVVQ 728
Query: 625 ELTEPTLALSA 635
L TL L+A
Sbjct: 729 HLLSRTLLLAA 739
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 69.7 bits (169), Expect = 8e-12
Identities = 117/467 (25%), Positives = 173/467 (37%), Gaps = 64/467 (13%)
Query: 200 GSGTEPPASTAALRTTPSPPSP-GPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPS 258
G+ T P A+ + + P+ P P G TPPA PP+ + A P + + ++ PS
Sbjct: 1239 GAPTTPAATPPSPKGGPATPPPKGAPTPPAATPPSLKGGL--ATPPHKGAPNPAVVTPPS 1296
Query: 259 DALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSE 318
KG GP P + T + P + G PP G PTPPA P
Sbjct: 1297 ----PKG-GP---ATSPPKGAPTPPAATPPSPKGSPGTPPPKGA------PTPPAVTPPS 1342
Query: 319 PVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLG 378
P + +P P + T P S + P+PPA P ++ PS G
Sbjct: 1343 P----KGTPTLPATTPSSKGGPTTPSSKE--GPTPPAATPSHKGGPAMTPPSP--KRGPA 1394
Query: 379 TVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELV 438
P+ DP PL S A P+ E G A+ L P ++ ++
Sbjct: 1395 IPSPKGDPTSPAVIPL------SPKKAPATPVTRE-GAATPSKGDLTPPAVTPVSLKKAP 1447
Query: 439 SHRSP-GEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARD 497
+ +P G P S + P T P P+E +SS P + PA
Sbjct: 1448 ATSAPKGGPATPSSKGDPTLPAVTPPS-PKEPPAPKQVATSSSPKK---------APATP 1497
Query: 498 ATFSTPSVRQPDPSAWLSSGPELTGMPRVRL--AAPLAVLPMEPLPPEPVRPAALLTPEA 555
A P++ P+ SS E+ P R AP A L + P + P L P A
Sbjct: 1498 APMGAPTL----PAVIPSSPKEVPATPSSRRDPIAPTATL-LSKKTPATLAPKEALIPPA 1552
Query: 556 SSVGGPDQARYL---ESAPGWPVGQEEWGVAHTSSPPSTQTLSLW----APTGVLLPSLV 608
+V P + + + AP P +E SSPP+ T S + +P +L+P V
Sbjct: 1553 MTVPSPKKTPAIPTPKEAPATPSSKE------ASSPPAV-TPSTYKGAPSPKELLIPPAV 1605
Query: 609 ELEYPFQAGRGASLQQELTEPTLALSAESHRPPELQDSVEGLSERPS 655
P +A ++ E A A P + L + P+
Sbjct: 1606 TSPSPKEAPTPPAVTPPSPEKGPATPAPKGTPTSPPVTPSSLKDSPT 1652
Score = 67.4 bits (163), Expect = 4e-11
Identities = 103/393 (26%), Positives = 145/393 (36%), Gaps = 48/393 (12%)
Query: 184 MAAPVLWTVESFFQCVGSGTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGP 243
+++PV SF + + A +P+PPSP P+ V P + V
Sbjct: 824 LSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPLSPKGVTL--- 880
Query: 244 AAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEA 303
+E + +++ P K+G PA TS+S P+ +A P+ P
Sbjct: 881 PPKETPTPSVVNLP---FPKEGPATPAPKQAPA-LSMTSSS--PKKARATPAPKGIPASP 934
Query: 304 GIPGHPTPPATLPSEPVEGVQASP---WRPRP--VLPTHPALTLPVSSDASSPSPPAPRP 358
G PTPPA P P +G A+P W P P P P S +P+PPA P
Sbjct: 935 SPKGAPTPPAATPPSP-KGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATP 993
Query: 359 ERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLL---RGLSSGDVAAPEPIMGEPG 415
P+ GP+ +G T P P GSP +G S+ A P G P
Sbjct: 994 PSPK----GGPATPSPKGAPT-PPAVTPPSPKGSPAATPFPKGASTPPAATPPSPKGSPA 1048
Query: 416 QASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGAR---- 471
PL + T AA P P + T P P P+ G
Sbjct: 1049 AT-----PLPKGAPTTPAATLPSPKGGPATPSLKGAPT----PPAATPPSPKGGPATPSP 1099
Query: 472 --GHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLA 529
M +++ PS GL+ P + A +TP+ P P L++ P G P A
Sbjct: 1100 KGAPMPPAATPPSPK---GGLATPPHKGAP-TTPAATPPSPKGGLATPPP-KGAPTTPAA 1154
Query: 530 ---APLAVLPMEPLPPEPVRPAALLTPEASSVG 559
+P L P P PAA TP + G
Sbjct: 1155 TPPSPKGGLATPPPKGAPTTPAA--TPPSPKGG 1185
Score = 62.8 bits (151), Expect = 1e-09
Identities = 130/494 (26%), Positives = 163/494 (32%), Gaps = 74/494 (14%)
Query: 201 SGTEPPASTAALRTTPSPPSP-GPETPPAGVPP------AASSQVWAAGPAAQEWLS--- 250
S + +T A + P+ PSP G TPPA PP A S WA P A S
Sbjct: 916 SSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTPPAATPPSPKG 975
Query: 251 RDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIP---G 307
P A P PA A P V P P A P G
Sbjct: 976 GPATPSPKGAPTPPAATPPSPKGGPATPSPKGAPTPPAVTP----PSPKGSPAATPFPKG 1031
Query: 308 HPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLP-------VSSDASSPSPPAPRPER 360
TPPA P P A+P P+ PT PA TLP S +P+PPA P
Sbjct: 1032 ASTPPAATPPSPKGSPAATP-LPKGA-PTTPAATLPSPKGGPATPSLKGAPTPPAATPPS 1089
Query: 361 PESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEP-GQASE 419
P+ GP+ +G PA +P SP G +A P P G P A+
Sbjct: 1090 PK----GGPATPSPKG-----APMPPAATPPSP-------KGGLATP-PHKGAPTTPAAT 1132
Query: 420 EFQP---LARPWRATLAAEELVSHRSP-----GEPQETCSGTEVERPRQTGPGLPREGAR 471
P LA P + SP P + T P GL +
Sbjct: 1133 PPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPK 1192
Query: 472 GHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAP 531
G ++ P G P+ +TP+ P P L++ P G P A P
Sbjct: 1193 GAPTTPAATPPSP---KGGLATPSPKGAPTTPAATPPSPKGGLAT-PSPKGAPTTPAATP 1248
Query: 532 LAVLPMEPLPP---EPVRPAA--------LLTPEASSVGGPDQARYLESAP-GWPVGQEE 579
+ PP P PAA L TP G P+ A +P G P
Sbjct: 1249 PSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHK--GAPNPAVVTPPSPKGGPATSPP 1306
Query: 580 WG--VAHTSSPPSTQ-TLSLWAPTGVLLPSLVELEYPFQAGR-GASLQQELTEPTLALSA 635
G ++PPS + + P G P V P A+ PT S
Sbjct: 1307 KGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSK 1366
Query: 636 ESHRPPELQDSVEG 649
E PP S +G
Sbjct: 1367 EGPTPPAATPSHKG 1380
Score = 57.0 bits (136), Expect = 5e-08
Identities = 101/393 (25%), Positives = 148/393 (37%), Gaps = 64/393 (16%)
Query: 200 GSGTEPPASTAALRTTP-SPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPS 258
G+ T P A+ + + +P +PP G TPPA PP+ P L P+
Sbjct: 1308 GAPTPPAATPPSPKGSPGTPPPKGAPTPPAVTPPS---------PKGTPTL-------PA 1351
Query: 259 DALAKKGLGPFLQTAKPARRGQTSASILP--RVVQAQRGPQPPPGEAGIP---GHPTPPA 313
+ KG GP T ++ G T + P + A P P G A IP G PT PA
Sbjct: 1352 TTPSSKG-GP---TTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPA-IPSPKGDPTSPA 1406
Query: 314 TLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDAS---SPSPPAPR--PERPESL---- 364
+P P + R P+ LT P + S +P+ AP+ P P S
Sbjct: 1407 VIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAPKGGPATPSSKGDPT 1466
Query: 365 --LVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQ 422
V+ PS V P K+P +P + G + P P S
Sbjct: 1467 LPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPM-GAPTLPAVIPSSPKEVPATPSSRRD 1525
Query: 423 PLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPS 482
P+A ATL +++ + +P E + T V P++T P +P + ++ S
Sbjct: 1526 PIAP--TATLLSKKTPATLAPKEALIPPAMT-VPSPKKT-PAIPTP-----KEAPATPSS 1576
Query: 483 QDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPL-AVLPMEPLP 541
++ P PA TPS + PS EL P V +P A P P
Sbjct: 1577 KEASSP-----PA-----VTPSTYKGAPSP-----KELLIPPAVTSPSPKEAPTPPAVTP 1621
Query: 542 PEPVRPAALLTPEASSVGGPDQARYLESAPGWP 574
P P + A P+ + P L+ +P P
Sbjct: 1622 PSPEKGPATPAPKGTPTSPPVTPSSLKDSPTSP 1654
Score = 52.8 bits (125), Expect = 1e-06
Identities = 98/457 (21%), Positives = 148/457 (32%), Gaps = 113/457 (24%)
Query: 208 STAALRTTPSPPSPGPETPPAGVP------PAASSQVWAAGPAAQEWLSRDLLHRPSDAL 261
+T R + PS G TPPA P PA S+ GPA
Sbjct: 1417 ATPVTREGAATPSKGDLTPPAVTPVSLKKAPATSAP--KGGPATP--------------- 1459
Query: 262 AKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVE 321
+ KG P L P + A P+ V P+ P G PT PA +PS P E
Sbjct: 1460 SSKG-DPTLPAVTPPSPKEPPA---PKQVATSSSPKKAPATPAPMGAPTLPAVIPSSPKE 1515
Query: 322 GVQASPWRPRPVLPT-------------------HPALTLP----------------VSS 346
R P+ PT PA+T+P S
Sbjct: 1516 VPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTVPSPKKTPAIPTPKEAPATPS 1575
Query: 347 DASSPSPPAPRPE------RPESLLV-------------SGPSVT---LTEGLGTVRPEQ 384
+ SPPA P P+ LL+ + P+VT +G T P+
Sbjct: 1576 SKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKEAPTPPAVTPPSPEKGPATPAPKG 1635
Query: 385 DPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPG 444
P P +P L+ + + + QAS+ P T E LV+
Sbjct: 1636 TPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGP---TALKEVLVAPAPES 1692
Query: 445 EP---QETCSGTEVERPRQTGPGL-----PREGARGHMDLSSSEPSQDIEGPGLSILPAR 496
P T G + ++ T P + + G++G + + P ++ +
Sbjct: 1693 TPIITAPTRKGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGK 1752
Query: 497 DATFSTPSVRQPDPSAWLS--------------SGPELTGMPRVRLAAPLAVLPMEPLPP 542
DA+ S P S + ++ P ++ PLA P+ LPP
Sbjct: 1753 DASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPP 1812
Query: 543 E----PVRPAALLTPEASSVGGPDQARYLESAPGWPV 575
+ P P +L + + D+ L P P+
Sbjct: 1813 KQQFLPSSPGLVLESPSKPLAPADEDELLPLIPPEPI 1849
Score = 52.0 bits (123), Expect = 2e-06
Identities = 100/386 (25%), Positives = 125/386 (32%), Gaps = 64/386 (16%)
Query: 207 ASTAALRTTPSPPS--PGPETPPAGVPPAAS-----SQVWAAGPAA---QEWLSRDLLHR 256
A A L P P P P PPAG PP S A P A +E + D
Sbjct: 719 APLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTED--SG 776
Query: 257 PSDALAKKGLGPFL-QTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATL 315
S + KG +L + P + + P + GP P G P P + L
Sbjct: 777 ASATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFL 836
Query: 316 PSEPV--EGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPA---PRPERPESLLVSGPS 370
P + +G + SP P P P S + SP P E P +V+ P
Sbjct: 837 PENSLSFQGSKDSPATTHSPTPPSPK-GAPTPSAVTPLSPKGVTLPPKETPTPSVVNLPF 895
Query: 371 VTLTEGLGTVRPEQDPAKS--PGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPW 428
EG T P+Q PA S SP R AP+ I P P A P
Sbjct: 896 P--KEGPATPAPKQAPALSMTSSSPKKARA-----TPAPKGIPASPSPKGAPTPPAATP- 947
Query: 429 RATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREG-----ARGHMDLSSSEPSQ 483
SP T S P P P+ G +G ++ P
Sbjct: 948 ------------PSPKGGPATPSPKWAPTPPAATPPSPKGGPATPSPKGAPTPPAATPPS 995
Query: 484 DIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLP------- 536
GP P+ + P+V P P P T P+ P A P
Sbjct: 996 PKGGPA---TPSPKGAPTPPAVTPPSP----KGSPAATPFPKGASTPPAATPPSPKGSPA 1048
Query: 537 MEPLPP-EPVRPAALLTPEASSVGGP 561
PLP P PAA L S GGP
Sbjct: 1049 ATPLPKGAPTTPAATL---PSPKGGP 1071
Score = 45.8 bits (107), Expect = 1e-04
Identities = 93/393 (23%), Positives = 134/393 (34%), Gaps = 63/393 (16%)
Query: 257 PSDALAKKGLGPFLQTAKPARR------GQTSASILPRVVQAQRGPQP----------PP 300
P LAKK LG L KPA +SAS++ + GP P
Sbjct: 586 PEATLAKKSLGEPLPIGKPASSMTSPLGVNSSASVIK--TDSYAGPDSAGPLLKSSLITP 643
Query: 301 GEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVL--------PTHPA-----LTLPVSSD 347
A P PA + +G P L HP TLP+
Sbjct: 644 TVAAFPLESADPAGVAPTTAKGTSTYTTTASPFLEGTVSLAPKNHPVKEGTLTTLPLVPT 703
Query: 348 ASSPSPPAPRPER---PESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDV 404
AS P AP P+ P + LV P + + P PA +P + G+S
Sbjct: 704 ASENCPVAPSPQNTCAPLATLVLAPEIPKS----VPSPSLPPAGTPPGTKKVDGIS--HT 757
Query: 405 AAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPG-EPQETCSGTEVERP----R 459
+A P+ P + E + AT +++ +++ + P + +RP
Sbjct: 758 SALAPVASSPKECPTEDSGAS----ATASSKGTLTYLADSPSPLGVSVSPQTKRPPTKKG 813
Query: 460 QTGPGLPREGARGHMD--LSSSEPSQDIEGPGLSILPARDATFSTPSVR-QPDPSAWLSS 516
GP P + +S P + G PA + + PS + P PSA
Sbjct: 814 SAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGAPTPSAVTPL 873
Query: 517 GPELTGMPRVRLAAPLAVLPMEPLPPE-PVRPAALLTPEAS-SVGGPDQARYLESAPGWP 574
P+ +P P V P P E P PA P S + P +AR + G P
Sbjct: 874 SPKGVTLPPKETPTPSVV--NLPFPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIP 931
Query: 575 VGQEEWG--VAHTSSPPSTQ-----TLSLWAPT 600
G ++PPS + WAPT
Sbjct: 932 ASPSPKGAPTPPAATPPSPKGGPATPSPKWAPT 964
Score = 38.9 bits (89), Expect = 0.015
Identities = 64/306 (20%), Positives = 106/306 (34%), Gaps = 54/306 (17%)
Query: 200 GSGTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSD 259
G+ T PP + ++L+ +P+ P+ A VP A+ GP A +++L P+
Sbjct: 1635 GTPTSPPVTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTA----LKEVLVAPAP 1690
Query: 260 ALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLP--- 316
P + + + TS I P P G G P LP
Sbjct: 1691 ESTPIITAPTRKGPQTKKSSATSPPICP-------DPSAKNGSKGPLSTVAPAPLLPVQK 1743
Query: 317 --SEPVEGVQASPWRPRPVLPTHPALTLPVSSDA--------------SSPSPPAPRPER 360
S+ +G AS P+ P + P+++ A ++PSPP P
Sbjct: 1744 DSSKTAKGKDASHSPKGPLAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLA 1803
Query: 361 PESLLVSGPS---VTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQA 417
P + P + + GL P + A + LL + PEPI G
Sbjct: 1804 PSPVPTLPPKQQFLPSSPGLVLESPSKPLAPADEDELL-------PLIPPEPISG----- 1851
Query: 418 SEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLS 477
P+++ L + + +S G P T S + G G + +L
Sbjct: 1852 -------GVPFQSVLV--NMPTPKSAGIPVPTPSAKQPVTKNNKGSGTESDSDESVPELE 1902
Query: 478 SSEPSQ 483
+ +Q
Sbjct: 1903 EQDSTQ 1908
Score = 34.7 bits (78), Expect = 0.29
Identities = 47/178 (26%), Positives = 65/178 (36%), Gaps = 33/178 (18%)
Query: 204 EPPASTA------ALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRP 257
+P A TA AL T + PGP PP P + AA A+ + P
Sbjct: 18 QPQAETAVLPMSSALSVTAALGQPGPTLPPPCSPAPQQCPLSAANQASPFPSPSTIASTP 77
Query: 258 SDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPS 317
+ PF Q++ S + LP P+ P + G P PA L
Sbjct: 78 LEV-------PFPQSS--------SGTALP----LGTAPEAPTFLPNLIGPPISPAAL-- 116
Query: 318 EPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTE 375
ASP P L P+ + P++ A +P P +LL S PSV + E
Sbjct: 117 -----ALASPMIA-PTLKGTPSSSAPLALVALAPHSVQKSSAFPPNLLTSPPSVAVAE 168
Score = 31.6 bits (70), Expect = 2.4
Identities = 76/299 (25%), Positives = 101/299 (33%), Gaps = 45/299 (15%)
Query: 310 TPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGP 369
T PA+L P QA + PT L ++ S + PE P S P
Sbjct: 534 TVPASLEGAPFSPAQAGLTTKKD--PTVLPLVQAAPKNSPSFQSTSSSPEIPLS-----P 586
Query: 370 SVTLTE-GLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPW 428
TL + LG P PA S SPL + SS V + G L P
Sbjct: 587 EATLAKKSLGEPLPIGKPASSMTSPLGVN--SSASVIKTDSYAGPDSAGPLLKSSLITP- 643
Query: 429 RATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGP 488
T+AA L S G T GT P L G + L+
Sbjct: 644 --TVAAFPLESADPAGVAPTTAKGTST-YTTTASPFL-----EGTVSLAPKNH------- 688
Query: 489 GLSILPARDATFST-PSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEP-LP---PE 543
P ++ T +T P V + ++ P+ T APLA L + P +P P
Sbjct: 689 -----PVKEGTLTTLPLVPTASENCPVAPSPQNT-------CAPLATLVLAPEIPKSVPS 736
Query: 544 PVRPAALLTPEASSVGGPDQARYLESAPGWP--VGQEEWGVAHTSSPPSTQTLSLWAPT 600
P P A P V G L P E+ G + T+S T T +P+
Sbjct: 737 PSLPPAGTPPGTKKVDGISHTSALAPVASSPKECPTEDSGASATASSKGTLTYLADSPS 795
Score = 31.2 bits (69), Expect = 3.2
Identities = 45/186 (24%), Positives = 67/186 (36%), Gaps = 20/186 (10%)
Query: 201 SGTEPPASTAALRTTPSPPSPGPETPPAGVPPAAS--SQVWAAGPAAQEWLSRDLLHRPS 258
SGT P TA T P GP PA + A+ + P++ L+ L P
Sbjct: 87 SGTALPLGTAPEAPTFLPNLIGPPISPAALALASPMIAPTLKGTPSSSAPLALVAL-APH 145
Query: 259 DALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPP------------PGEAGIP 306
P L T+ P+ S S++ + A P P P G P
Sbjct: 146 SVQKSSAFPPNLLTSPPSVAVAESGSVI--TLSAPIAPSEPKTNLNKVPSEVVPNPKGTP 203
Query: 307 GHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDA---SSPSPPAPRPERPES 363
P +T+P V + + + T P TL ++S ++ S P+ P S
Sbjct: 204 SPPCIVSTVPYHCVTPMASIQSGVASLPQTTPTTTLAIASPQVKDTTISSVLISPQNPGS 263
Query: 364 LLVSGP 369
L + GP
Sbjct: 264 LSLKGP 269
>gi|148762969 myeloid/lymphoid or mixed-lineage leukemia 2 [Homo
sapiens]
Length = 5537
Score = 68.2 bits (165), Expect = 2e-11
Identities = 123/466 (26%), Positives = 155/466 (33%), Gaps = 67/466 (14%)
Query: 203 TEPPASTAALRTTP--SPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDA 260
T PP + L P SP SP PE P PP AS P + LS P
Sbjct: 563 TSPPPEASRLSPPPEESPMSPPPEESPMSPPPEASR---LFPPFEESPLSPPPEESP--- 616
Query: 261 LAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPV 320
L A R P + P PP E P P + S P
Sbjct: 617 ---------LSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLS-PLPVVSRLSPPP 666
Query: 321 EGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTV 380
E SP P PT P P +S S P +P PE S P + L ++
Sbjct: 667 EESPLSP--PPEESPTSPP---PEASRLSPPPEDSPTSPPPEDSPASPPP---EDSLMSL 718
Query: 381 RPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSH 440
E+ P L S G +P P EE RP L+ + H
Sbjct: 719 PLEESPLLPLPEEPQLCPRSEGPHLSPRP---------EEPHLSPRPEEPHLSPQAEEPH 769
Query: 441 RSPGEPQETCSGTEVER----PRQTGPGLPREGARGHMDLSSSEP--SQDIEGPGLS--- 491
SP +P+E C E P+ GP L + H+ + EP S E P LS
Sbjct: 770 LSP-QPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQP 828
Query: 492 -------------ILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPME 538
+ P + + +P + +P S PE G + AP LP+
Sbjct: 829 EESHLSPQSEEPCLSPRPEESHLSPELEKPPLSPRPEKPPEEPG----QCPAP-EELPLF 883
Query: 539 PLPPEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTLS--L 596
P P EP L P S G P + E P P G+ P LS +
Sbjct: 884 PPPGEPSLSPLLGEPALSEPGEPPLSPLPEELPLSPSGEPSLSPQLMPPDPLPPPLSPII 943
Query: 597 WAPTGVLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPPE 642
A L L ELEYPF A + + L P L PPE
Sbjct: 944 TAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISP--PPE 987
Score = 59.7 bits (143), Expect = 8e-09
Identities = 96/361 (26%), Positives = 130/361 (36%), Gaps = 53/361 (14%)
Query: 322 GVQASPWRPRPVLPTHPALTLPVSSDASSP---SPPAPRPER------PESLLVSGPSVT 372
GVQ P P+ P L P S S P SP +P PE PE L P+
Sbjct: 423 GVQLEPQLEAPLNEEMPLLPPPEESPLSPPPEESPTSPPPEASRLSPPPEEL----PASP 478
Query: 373 LTEGLGTVRPEQD---------------PAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQA 417
L E L RP ++ P SP SPL LS + + P P + P
Sbjct: 479 LPEALHLSRPLEESPLSPPPEESPLSPPPESSPFSPLEESPLSPPEESPPSPALETPLSP 538
Query: 418 SEEFQPLARPWRATLAA---EELVSHRSPGEPQETCSGTEVERPRQTGP-----GLPREG 469
E PL+ P+ + + EEL + SP S E P P P E
Sbjct: 539 PPEASPLSPPFEESPLSPPPEELPT--SPPPEASRLSPPPEESPMSPPPEESPMSPPPEA 596
Query: 470 ARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPS---VRQPDPSAWLSSGPELTGMPRV 526
+R S S E LS P P + P + +S PE++ + +
Sbjct: 597 SRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPPEVSRLSPL 656
Query: 527 RLAAPLAVLPME-PLPPEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHT 585
+ + L+ P E PL P P PEAS + P E +P P ++ +
Sbjct: 657 PVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPP-----EDSPTSPPPED----SPA 707
Query: 586 SSPPSTQTLSLWAPTGVLLPSLVELEYPFQAGRGASLQQELTEPTLA-LSAESHRPPELQ 644
S PP +SL LLP L E G L EP L+ E H P+ +
Sbjct: 708 SPPPEDSLMSLPLEESPLLP-LPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSPQAE 766
Query: 645 D 645
+
Sbjct: 767 E 767
Score = 58.5 bits (140), Expect = 2e-08
Identities = 117/471 (24%), Positives = 157/471 (33%), Gaps = 93/471 (19%)
Query: 217 SPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPA 276
SP SP PE P PP AS L P + L L L ++P
Sbjct: 447 SPLSPPPEESPTSPPPEASR-----------------LSPPPEELPASPLPEALHLSRPL 489
Query: 277 RRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPT 336
S PPP E+ + PP + P P+E SP P P
Sbjct: 490 EESPLS---------------PPPEESPLS---PPPESSPFSPLE---ESPLSPPEESPP 528
Query: 337 HPALTLPVS--SDASSPSPP---APRPERPESLLVSGP------SVTLTEGLGTVRPEQD 385
PAL P+S +AS SPP +P PE L S P S E + PE+
Sbjct: 529 SPALETPLSPPPEASPLSPPFEESPLSPPPEELPTSPPPEASRLSPPPEESPMSPPPEES 588
Query: 386 P-AKSPGSPLLLRGLSSGDVAAP--EPIMGEPGQASE--------------EFQPLARPW 428
P + P + L ++ P E + P +AS E P++ P
Sbjct: 589 PMSPPPEASRLFPPFEESPLSPPPEESPLSPPPEASRLSPPPEDSPMSPPPEESPMSPPP 648
Query: 429 RAT-LAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEG 487
+ L+ +VS SP + S E P P R +S P
Sbjct: 649 EVSRLSPLPVVSRLSPPPEESPLSPPPEESPTSPPPEASRLSPPPEDSPTSPPPEDSPAS 708
Query: 488 PGLSILPARDATFSTPSVRQP------DPSAW-LSSGPELTGMPRVRLAAP------LAV 534
P P D+ S P P +P S GP L+ P +P L+
Sbjct: 709 P-----PPEDSLMSLPLEESPLLPLPEEPQLCPRSEGPHLSPRPEEPHLSPRPEEPHLSP 763
Query: 535 LPMEP-LPPEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQT 593
EP L P+P P PE + + +L P + H S P
Sbjct: 764 QAEEPHLSPQPEEPCLCAVPEEPHLSPQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPC 823
Query: 594 LSLWAPTGVLLPSLVELEYPFQAGR--GASLQQELTEPTLALSAESHRPPE 642
LS L P + E P + R + L EL +P LS +PPE
Sbjct: 824 LSPQPEESHLSP---QSEEPCLSPRPEESHLSPELEKP--PLSPRPEKPPE 869
Score = 53.5 bits (127), Expect = 6e-07
Identities = 115/417 (27%), Positives = 144/417 (34%), Gaps = 81/417 (19%)
Query: 201 SGTEPPASTAALRTTP--SPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPS 258
S T PP + L P SP SP PE PA PP S + P + LL P
Sbjct: 678 SPTSPPPEASRLSPPPEDSPTSPPPEDSPASPPPEDSLM---SLPLEES----PLLPLPE 730
Query: 259 D-ALAKKGLGPFLQTAKPARRGQT----SASILPRVVQAQRGPQP-PPGEAGIPGHP--T 310
+ L + GP L + +P + + P+ + PQP P +P P +
Sbjct: 731 EPQLCPRSEGPHL-SPRPEEPHLSPRPEEPHLSPQAEEPHLSPQPEEPCLCAVPEEPHLS 789
Query: 311 PPATLP--SEPVEGVQASPWRPRPVL---PTHPALT-LPVSSDASSPSPPAPRPERPESL 364
P A P S E + SP P L P P L+ P S S S RPE
Sbjct: 790 PQAEGPHLSPQPEELHLSPQTEEPHLSPVPEEPCLSPQPEESHLSPQSEEPCLSPRPEES 849
Query: 365 LVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQ--ASEE-- 420
+S PE + K P SP PE EPGQ A EE
Sbjct: 850 HLS--------------PELE--KPPLSP------------RPEKPPEEPGQCPAPEELP 881
Query: 421 -FQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSS 479
F P P + L E +S PGEP P P G LS
Sbjct: 882 LFPPPGEPSLSPLLGEPALS--EPGEP-----------PLSPLPEELPLSPSGEPSLSPQ 928
Query: 480 EPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEP 539
D P LS + T + P P G + P LAAP+ P+ P
Sbjct: 929 LMPPDPLPPPLSPI----ITAAAPPALSPLGELEYPFGAKGDSDPESPLAAPILETPISP 984
Query: 540 LP------PEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPS 590
P PEPV P +L P S GP +E P + + +SPPS
Sbjct: 985 PPEANCTDPEPV-PPMILPPSPGSPVGPASPILMEPLPPQCSPLLQHSLVPQNSPPS 1040
Score = 47.8 bits (112), Expect = 3e-05
Identities = 107/461 (23%), Positives = 151/461 (32%), Gaps = 81/461 (17%)
Query: 203 TEPPASTAALRTTPSPPSP--GPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDA 260
T PP + R PS P P P P S G A++ LS A
Sbjct: 2228 TTPPGTP---RHQPSTPDPFLKPRCPSLDNLAVPESPGVGGGKASEPLLSPPPFGESRKA 2284
Query: 261 LA--KKGLGPFLQTAKPARRG----QTSASIL-------PRVVQAQRGPQPPPGEAGIPG 307
L K+ LG + P G +S + L P V +A P+ E PG
Sbjct: 2285 LEVKKEELGASSPSYGPPNLGFVDSPSSGTHLGGLELKTPDVFKAPLTPRASQVEPQSPG 2344
Query: 308 HPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSD---ASSPSPPAPRPERPESL 364
P P P + + SP P+HP + P S A P P P+P PES
Sbjct: 2345 LGLRPQEPP--PAQALAPSP-------PSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESC 2395
Query: 365 LVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVA---------APEPIMGEPG 415
P ++ V S SPL R LS+ +P+P P
Sbjct: 2396 CALPPRSLPSDPFSRVPASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPS 2455
Query: 416 --QASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARG- 472
Q+ + F PL +P R P P+ + G P G
Sbjct: 2456 RPQSRDPFAPLHKPPR-------------PQPPEVAFKAGSLAHTSLGAGGFPAALPAGP 2502
Query: 473 ----HMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRL 528
H + S +P + PG A TPS + + P+ G P ++
Sbjct: 2503 AGELHAKVPSGQPPNFVRSPGTG------AFVGTPSPMR-------FTFPQAVGEPSLKP 2549
Query: 529 AAPLAVLPMEPLPPEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSP 588
P LP PP + P ++G P Y + + G + + S
Sbjct: 2550 PVPQPGLP----PPHGINSHFGPGP---TLGKPQSTNYTVATGNFHPSGSPLGPS-SGST 2601
Query: 589 PSTQTLSLWAPTGVLLPSLVELEYPFQAGRGASLQQELTEP 629
+ LS P VL P + P+ GAS + +T P
Sbjct: 2602 GESYGLSPLRPPSVLPPPAPDGSLPY-LSHGASQRSGITSP 2641
Score = 42.7 bits (99), Expect = 0.001
Identities = 109/493 (22%), Positives = 155/493 (31%), Gaps = 124/493 (25%)
Query: 197 QCVGSGTEPPASTAALRTTPSPPS-------------------------PGPET----PP 227
Q G G P A PSPPS P PE+ PP
Sbjct: 2341 QSPGLGLRPQEPPPAQALAPSPPSHPDIFRPGSYTDPYAQPPLTPRPQPPPPESCCALPP 2400
Query: 228 AGVPPAASSQVWAAGPAAQEWLSRDLLHRP--SDALAKKGLGPFLQTAKPARRGQTSASI 285
+P S+V A P +Q L RP ++A + P Q+ P R +
Sbjct: 2401 RSLPSDPFSRV-PASPQSQSSSQSPLTPRPLSAEAFCPSPVTPRFQSPDPYSRPPSRPQS 2459
Query: 286 LPRVVQAQRGPQPPPGE----AGIPGHPTP-----PATLPSEPVEGVQASPWRPRPV--- 333
+ P+P P E AG H + PA LP+ P + A +P
Sbjct: 2460 RDPFAPLHKPPRPQPPEVAFKAGSLAHTSLGAGGFPAALPAGPAGELHAKVPSGQPPNFV 2519
Query: 334 ----------LPTHPALTLPVSSDASSPSPPAPRPERPESLLVS---GPSVTL------- 373
P+ T P + S PP P+P P ++ GP TL
Sbjct: 2520 RSPGTGAFVGTPSPMRFTFPQAVGEPSLKPPVPQPGLPPPHGINSHFGPGPTLGKPQSTN 2579
Query: 374 ------------------------TEGLGTVRPEQ---DPAKSPGSPLLLRGLSS-GDVA 405
+ GL +RP PA P L G S +
Sbjct: 2580 YTVATGNFHPSGSPLGPSSGSTGESYGLSPLRPPSVLPPPAPDGSLPYLSHGASQRSGIT 2639
Query: 406 APEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQ----- 460
+P +PG ++LA EL + PG S TE+E+ RQ
Sbjct: 2640 SPVEKREDPGTG----------MGSSLATAELPGTQDPG--MSGLSQTELEKQRQRQRLR 2687
Query: 461 ---TGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSG 517
+ R R + +++ + PG F S R P A
Sbjct: 2688 ELLIRQQIQRNTLRQEKETAAAAAGA-VGPPGSWGAEPSSPAFEQLS-RGQTPFAGTQDK 2745
Query: 518 PELTGMPRVRLAAPL---AVLPME---PLPPEPVRPAALLTPEASSVGGP----DQARYL 567
L G+P +L+ P+ P + PP P P+++ VGG +A Y
Sbjct: 2746 SSLVGLPPSKLSGPILGPGSFPSDDRLSRPPPPATPSSMDVNSRQLVGGSQAFYQRAPYP 2805
Query: 568 ESAPGWPVGQEEW 580
S P Q+ W
Sbjct: 2806 GSLPLQQQQQQLW 2818
Score = 39.7 bits (91), Expect = 0.009
Identities = 101/410 (24%), Positives = 144/410 (35%), Gaps = 84/410 (20%)
Query: 197 QCVGSGTEPPASTAALRTTPSPPSPGPETPPAG-----VPPAASSQVWAAGPAAQEWLSR 251
Q V G PA L+ SP + GP G V PA SS+ GP+ +
Sbjct: 3993 QQVALGPGMPAKP--LQHFSSPGALGPTLLLTGKEQNTVDPAVSSEA-TEGPSTHQGGPL 4049
Query: 252 DLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTP 311
+ P + G KP+ G + +++ Q PQP P + P
Sbjct: 4050 AIGTTPESMATEPG------EVKPSLSGDS------QLLLVQPQPQPQPSSLQLQ----P 4093
Query: 312 PATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASS-----PSPPAPRPERPESLLV 366
P LP + + V +H L SS+ASS P ++P S+
Sbjct: 4094 PLRLPGQQQQQVSLLHTAGGG---SHGQLGSGSSSEASSVPHLLAQPSVSLGDQPGSMTQ 4150
Query: 367 S--GPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPL 424
+ GP + E RP Q+ P P L SG IM GQ + Q
Sbjct: 4151 NLLGPQQPMLE-----RPMQNNT-GPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQ-- 4202
Query: 425 ARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQD 484
LA + H SP + Q+ ++R Q + + + P Q+
Sbjct: 4203 -----GVLAKNPQLRHLSP-QQQQQLQALLMQRQLQQSQAVRQ-----------TPPYQE 4245
Query: 485 IEGPGLSILPARDATFSTPSVR-----QPDPSAWLSSGPELTGMPRVRLAAPLAVL---- 535
PG P + P + Q P L +GP G PR L AP L
Sbjct: 4246 ---PGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPPR--LPAPPGALSTGP 4300
Query: 536 ---PMEPLPP-----EPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQ 577
P+ P PP EP RP+ L +P + P +A+ + PG P Q
Sbjct: 4301 VLGPVHPTPPPSSPQEPKRPSQLPSPSSQL---PTEAQLPPTHPGTPKPQ 4347
Score = 38.5 bits (88), Expect = 0.020
Identities = 32/104 (30%), Positives = 43/104 (41%), Gaps = 8/104 (7%)
Query: 330 PRPVLPTHPALTLPVSS----DASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQD 385
P P PT + T VS+ S+P P P P P S L P+ TE L V +
Sbjct: 4884 PAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSP--PPSPLAPSPASPPTEPL--VELPTE 4939
Query: 386 PAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWR 429
P P P L SS + A P+P P + + P + W+
Sbjct: 4940 PLAEPPVPSPLPLASSPESARPKPRARPPEEGEDSRPPRLKKWK 4983
Score = 37.7 bits (86), Expect = 0.034
Identities = 45/192 (23%), Positives = 63/192 (32%), Gaps = 54/192 (28%)
Query: 214 TTPSPPSPGP------ETPPAGVPP-------------AASSQVWAAGPAAQEWLSRDLL 254
T P PP PGP P G+ P A + Q+ P Q+ L L+
Sbjct: 4168 TGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQQQQLQALLM 4227
Query: 255 HRP-SDALAKKGLGPFLQTAKPARRGQTSASILPR-----------VVQAQRGPQP---- 298
R + A + P+ + Q P+ + + GP+P
Sbjct: 4228 QRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELGAGPRPQGPP 4287
Query: 299 ----PPGEAGI-----PGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDAS 349
PPG P HPTPP + P EP RP P+ LP +
Sbjct: 4288 RLPAPPGALSTGPVLGPVHPTPPPSSPQEP----------KRPSQLPSPSSQLPTEAQLP 4337
Query: 350 SPSPPAPRPERP 361
P P+P+ P
Sbjct: 4338 PTHPGTPKPQGP 4349
Score = 35.8 bits (81), Expect = 0.13
Identities = 93/356 (26%), Positives = 119/356 (33%), Gaps = 114/356 (32%)
Query: 309 PTPPATLPSEPVEGVQ---ASPWRPRPVLPTHP--------------------------A 339
PTPP++LP P VQ + P L HP A
Sbjct: 4620 PTPPSSLPPTPPPSVQQKMVNGVTPSEELGEHPKDAASARDSERALRDTSEVKSLDLLAA 4679
Query: 340 LTLP---------VSSDASSPSPPAPRP-ERPESLLVSGPSVTLTEGLGTVRPEQ-DPAK 388
L P + SD S SP + P PES+L G LG+ R EQ D A
Sbjct: 4680 LPTPPHNQTEDVRMESDEDSDSPDSIVPASSPESIL--GEEAPRFPHLGSGRWEQEDRAL 4737
Query: 389 SPGSPLLLR------------GLSSGDVAAPEPIMG-EPGQASEEFQPLARPWRAT---- 431
SP PL+ R G +V P+ E G+ SE L A
Sbjct: 4738 SPVIPLIPRASIPVFPDTKPYGALGLEVPGKLPVTTWEKGKGSEVSVMLTVSAAAAKNLN 4797
Query: 432 ---LAAEELVSHRSPGE-----PQETC-SGTEVERPRQTGPGLPREGARG---------- 472
+A EL+S + P P+ +GTE ++ GPG +G G
Sbjct: 4798 GVMVAVAELLSMKIPNSYEVLFPESPARAGTEPKKGEAEGPGGKEKGLEGKSPDTGPDWL 4857
Query: 473 --------------HMDLSS---------SEPSQDIEGPGLSILPARDATFSTPSVRQPD 509
+D+ S P+Q +S L R + P P
Sbjct: 4858 KQFDAVLPGYTLKSQLDILSLLKQESPAPEPPTQHSYTYNVSNLDVRQLSAPPPEEPSPP 4917
Query: 510 PSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEASSVGGPDQAR 565
PS L P PL LP EPL PV P+ L P ASS P+ AR
Sbjct: 4918 PSP-------LAPSPASPPTEPLVELPTEPLAEPPV-PSPL--PLASS---PESAR 4960
Score = 35.0 bits (79), Expect = 0.22
Identities = 38/147 (25%), Positives = 52/147 (35%), Gaps = 7/147 (4%)
Query: 219 PSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKK-GLGPFLQTAKPAR 277
P G P G + GP +WL + P L + + L+ PA
Sbjct: 4830 PKKGEAEGPGGKEKGLEGKSPDTGP---DWLKQFDAVLPGYTLKSQLDILSLLKQESPAP 4886
Query: 278 RGQTSASILPRV--VQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVLP 335
T S V + ++ PPP E P P P+ S P E + P P P
Sbjct: 4887 EPPTQHSYTYNVSNLDVRQLSAPPPEEPSPPPSPLAPSPA-SPPTEPLVELPTEPLAEPP 4945
Query: 336 THPALTLPVSSDASSPSPPAPRPERPE 362
L L S +++ P P A PE E
Sbjct: 4946 VPSPLPLASSPESARPKPRARPPEEGE 4972
Score = 30.8 bits (68), Expect = 4.1
Identities = 53/201 (26%), Positives = 71/201 (35%), Gaps = 32/201 (15%)
Query: 285 ILPRVVQAQRGPQPP-PGEA-----GIPGHPTPPAT-LPSEPVEGVQASPWRPRPVLPTH 337
+L R +Q GPQPP PG G+PG P ++GV A + R + P
Sbjct: 4159 MLERPMQNNTGPQPPKPGPVLQSGQGLPGVGIMPTVGQLRAQLQGVLAKNPQLRHLSPQQ 4218
Query: 338 ----PALTLP---VSSDASSPSPPAPRPERPESLL------------VSGPSVTLTEGLG 378
AL + S A +PP P S L GP + LG
Sbjct: 4219 QQQLQALLMQRQLQQSQAVRQTPPYQEPGTQTSPLQGLLGCQPQLGGFPGPQTGPLQELG 4278
Query: 379 TVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRAT-LAAEEL 437
Q P + P P LS+G V P P E +P P ++ L E
Sbjct: 4279 AGPRPQGPPRLPAPP---GALSTGPVLGPVHPTPPPSSPQEPKRPSQLPSPSSQLPTEAQ 4335
Query: 438 VSHRSPGEPQETCSGTEVERP 458
+ PG P+ G +E P
Sbjct: 4336 LPPTHPGTPKP--QGPTLEPP 4354
Score = 29.6 bits (65), Expect = 9.2
Identities = 59/240 (24%), Positives = 79/240 (32%), Gaps = 40/240 (16%)
Query: 211 ALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKGLGPFL 270
A+R TP PG +T P Q+ P Q + L + G GP
Sbjct: 4236 AVRQTPPYQEPGTQTSPLQGLLGCQPQL-GGFPGPQ-----------TGPLQELGAGPRP 4283
Query: 271 QTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQASPWRP 330
Q P R ++ V P PPP P P P+ LPS P
Sbjct: 4284 QG--PPRLPAPPGALSTGPVLGPVHPTPPPSS---PQEPKRPSQLPS------------P 4326
Query: 331 RPVLPTHPALTLPVSSDASSPSPPA--PRPERPESLLVSGPSVTLTEGLGTVRPEQDPAK 388
LPT L P P P P P R ++GLG P + A+
Sbjct: 4327 SSQLPTEAQLP-PTHPGTPKPQGPTLEPPPGRVSPAAAQLADTLFSKGLGPWDPPDNLAE 4385
Query: 389 S--PGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEP 446
+ P L+ G ++ E Q S + +P P L A+ V + GEP
Sbjct: 4386 TQKPEQSSLVPGHLD---QVNGQVVPEASQLSIKQEPREEP--CALGAQS-VKREANGEP 4439
>gi|189181724 proteoglycan 4 isoform D [Homo sapiens]
Length = 1270
Score = 66.2 bits (160), Expect = 9e-11
Identities = 90/385 (23%), Positives = 126/385 (32%), Gaps = 45/385 (11%)
Query: 206 PASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKG 265
PAST TP+ P TP P S P + + P+ K+
Sbjct: 224 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKS-----APTTPKEPAPTTTKEPAPTTPKEP 278
Query: 266 LGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPT---PPATLPSEPV-- 320
T +PA SA P+ +P P P T P T P EP
Sbjct: 279 AP--TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 336
Query: 321 --EGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAP-RPERPESLLVSGPSVTLTEGL 377
E +P P P P PA T P ++P PAP + P P+ T T+
Sbjct: 337 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 396
Query: 378 GTVRPEQDPAKSPGSPLLLRGLSSGDVAAP------EPIMGEPGQASEEFQPLARPWRAT 431
T E P + +P + S P EP P + + P
Sbjct: 397 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 456
Query: 432 LAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLS 491
A +P P+E T P++T P P++ L+ + P +
Sbjct: 457 EPAPTTTKKPAPTTPKEPAPTT----PKETAPTTPKK-------LTPTTPEKLAPTTPEK 505
Query: 492 ILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAALL 551
P + + +P P+ PE + AAP P EP P P PA
Sbjct: 506 PAPTTPEELAPTTPEEPTPTT-----PEEPAPTTPKAAAPNT--PKEPAPTTPKEPAP-T 557
Query: 552 TPEASSVGGPDQARYLESAPGWPVG 576
TP+ + P E+AP P G
Sbjct: 558 TPKEPAPTTPK-----ETAPTTPKG 577
Score = 62.4 bits (150), Expect = 1e-09
Identities = 81/399 (20%), Positives = 126/399 (31%), Gaps = 33/399 (8%)
Query: 206 PASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHR-PSDALAKK 264
P +T + TTP P+P PA P + PA S + P+ KK
Sbjct: 249 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 308
Query: 265 GLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQ 324
+ P + + + P+ P P TP P+ P +
Sbjct: 309 PAPTTPKEPAPTTPKEPTPTT----------PKEPAPTTKEPAPTTPKEPAPTAPKKPAP 358
Query: 325 ASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQ 384
+P P P P PA T ++P PAP + P+ T T+ T E
Sbjct: 359 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 418
Query: 385 DPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPG 444
P + P +P P + + P A +P
Sbjct: 419 SPTTTK-EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 477
Query: 445 EPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPS 504
P+ET T P++ P P + L+ + P + + P + +
Sbjct: 478 TPKETAPTT----PKKLTPTTPEK-------LAPTTPEKPAPTTPEELAPTTPEEPTPTT 526
Query: 505 VRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEA--SSVGGPD 562
+P P+ ++ P P P EP P P PA E ++ G
Sbjct: 527 PEEPAPTTPKAAAPNTP-------KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 579
Query: 563 QARYLESAPGWPVGQEEWGVAHTSS-PPSTQTLSLWAPT 600
E AP P +A T++ P++ T APT
Sbjct: 580 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 618
Score = 56.2 bits (134), Expect = 9e-08
Identities = 69/316 (21%), Positives = 103/316 (32%), Gaps = 37/316 (11%)
Query: 273 AKPARRGQTSASILPRVVQAQRGPQPPPGEAGI-PGHPTPPA-----TLPSEPV----EG 322
AKP + +T+ + P P A P PTP T P EP +
Sbjct: 195 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 254
Query: 323 VQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRP 382
+P P P PA T P ++ PAP + P+ T + P
Sbjct: 255 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 314
Query: 383 EQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRS 442
++ +P P + P P EP + + P + + + +
Sbjct: 315 KEPAPTTPKEP------TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 368
Query: 443 PGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFST 502
P EP T + ++ P P+E A P+ P + PA T S
Sbjct: 369 PKEPAPTTT-------KEPSPTTPKEPA----------PTTTKSAPTTTKEPAPTTTKSA 411
Query: 503 PSV-RQPDPSAWLSSGPELTGMPR-VRLAAPLAVLPMEPLPPEPVRPAALLT--PEASSV 558
P+ ++P P+ P P P P EP P P PA T P ++
Sbjct: 412 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP 471
Query: 559 GGPDQARYLESAPGWP 574
P E+AP P
Sbjct: 472 KEPAPTTPKETAPTTP 487
Score = 56.2 bits (134), Expect = 9e-08
Identities = 94/477 (19%), Positives = 145/477 (30%), Gaps = 49/477 (10%)
Query: 203 TEPPASTAALRTTPSPPSPGPETPPAGVP---------------------PAASSQVWA- 240
T+ PA T +P P P TP P PA +++ A
Sbjct: 283 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 342
Query: 241 -----AGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRG 295
P A + + P+ K+ + P + + + +
Sbjct: 343 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 402
Query: 296 PQPPPGEAG--IPGHPTPPAT---LPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASS 350
P P ++ P P+P T P+ P E +P +P P P PA T P ++
Sbjct: 403 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 462
Query: 351 PSPPAP-RPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEP 409
PAP P+ P + T + L PE+ +P P EP
Sbjct: 463 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 522
Query: 410 IMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREG 469
P + + A P A +P P+E T P++T P P+
Sbjct: 523 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT----PKETAPTTPKGT 578
Query: 470 ARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLA 529
A L P+ + + P ++ + +P P+ + P
Sbjct: 579 A--PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP-------K 629
Query: 530 APLAVLPMEPLP--PEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSS 587
P P EP P P+ P L P ++ P + P A T+
Sbjct: 630 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 689
Query: 588 PPSTQTLSLW-APTGVLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPPEL 643
+ T APT P+ E P S EPT + PEL
Sbjct: 690 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 746
Score = 52.8 bits (125), Expect = 1e-06
Identities = 62/268 (23%), Positives = 87/268 (32%), Gaps = 38/268 (14%)
Query: 204 EPPAST---AALRTTPSPPSPGPETPPAGVPPA--ASSQVWAAGPAAQEWLSRDLLHRPS 258
E PA T AA TP P+P PA P A + P + + L P+
Sbjct: 528 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 587
Query: 259 DALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSE 318
KK PA P+ + +P P TP T P+
Sbjct: 588 PTTPKK----------PA----------PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 627
Query: 319 PVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLG 378
P E +P P P P A T ++P PAP+ P + GP+ T ++
Sbjct: 628 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKGPTSTTSDKPA 685
Query: 379 TVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELV 438
P++ +P P ++ AP P SE P T E
Sbjct: 686 PTTPKETAPTTPKEP----APTTPKKPAPTTPETPPPTTSEVSTP-------TTTKEPTT 734
Query: 439 SHRSPGEPQETCSGTEVERPRQTGPGLP 466
H+SP E S + + P P
Sbjct: 735 IHKSPDESTPELSAEPTPKALENSPKEP 762
Score = 40.8 bits (94), Expect = 0.004
Identities = 67/356 (18%), Positives = 111/356 (31%), Gaps = 31/356 (8%)
Query: 202 GTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDAL 261
GT P TTP P+P P P +++ +P+
Sbjct: 577 GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT-----------------CDKPAPT- 618
Query: 262 AKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVE 321
KG P + A P+ +P P P P P P+
Sbjct: 619 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKG 675
Query: 322 GVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAP-RPERPESLLVSGPSVTLTEGLGTV 380
+ +P P P A T P ++P PAP PE P + T T+ T+
Sbjct: 676 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 735
Query: 381 RPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSH 440
D + S + A E EPG + + +P T A ++
Sbjct: 736 HKSPDESTPELS-------AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 788
Query: 441 RSPGEPQETCSGTEVERPRQTGPGLPREG-ARGHMDLSSSEPSQDIEGPGLSILPARDAT 499
P+ T + ++ + T E +S +QD ++ L
Sbjct: 789 DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 848
Query: 500 FSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPE-PVRPAALLTPE 554
+ ++ + + + PE T P+ R A P P + P +P + P+
Sbjct: 849 PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPK 904
Score = 35.0 bits (79), Expect = 0.22
Identities = 44/205 (21%), Positives = 68/205 (33%), Gaps = 26/205 (12%)
Query: 413 EPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARG 472
E +++E Q + + LA V + + + T G + P++ P P+E A
Sbjct: 168 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA-- 225
Query: 473 HMDLSSSEPSQDI--EGPGLSILPARDATFSTP---------SVRQPDPSAWLSSGPELT 521
+ EP+ P PA T S P + ++P P+ P T
Sbjct: 226 --STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 283
Query: 522 GMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWG 581
P P EP P P +PA E + + P P
Sbjct: 284 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-----------PTTPKEPTPTTPKE 332
Query: 582 VAHTSSPPSTQTLSLWAPTGVLLPS 606
A T+ P+ T APT P+
Sbjct: 333 PAPTTKEPAPTTPKEPAPTAPKKPA 357
>gi|189181722 proteoglycan 4 isoform C [Homo sapiens]
Length = 1311
Score = 66.2 bits (160), Expect = 9e-11
Identities = 90/385 (23%), Positives = 126/385 (32%), Gaps = 45/385 (11%)
Query: 206 PASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKG 265
PAST TP+ P TP P S P + + P+ K+
Sbjct: 265 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKS-----APTTPKEPAPTTTKEPAPTTPKEP 319
Query: 266 LGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPT---PPATLPSEPV-- 320
T +PA SA P+ +P P P T P T P EP
Sbjct: 320 AP--TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 377
Query: 321 --EGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAP-RPERPESLLVSGPSVTLTEGL 377
E +P P P P PA T P ++P PAP + P P+ T T+
Sbjct: 378 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 437
Query: 378 GTVRPEQDPAKSPGSPLLLRGLSSGDVAAP------EPIMGEPGQASEEFQPLARPWRAT 431
T E P + +P + S P EP P + + P
Sbjct: 438 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 497
Query: 432 LAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLS 491
A +P P+E T P++T P P++ L+ + P +
Sbjct: 498 EPAPTTTKKPAPTTPKEPAPTT----PKETAPTTPKK-------LTPTTPEKLAPTTPEK 546
Query: 492 ILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAALL 551
P + + +P P+ PE + AAP P EP P P PA
Sbjct: 547 PAPTTPEELAPTTPEEPTPTT-----PEEPAPTTPKAAAPNT--PKEPAPTTPKEPAP-T 598
Query: 552 TPEASSVGGPDQARYLESAPGWPVG 576
TP+ + P E+AP P G
Sbjct: 599 TPKEPAPTTPK-----ETAPTTPKG 618
Score = 62.4 bits (150), Expect = 1e-09
Identities = 81/399 (20%), Positives = 126/399 (31%), Gaps = 33/399 (8%)
Query: 206 PASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHR-PSDALAKK 264
P +T + TTP P+P PA P + PA S + P+ KK
Sbjct: 290 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 349
Query: 265 GLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQ 324
+ P + + + P+ P P TP P+ P +
Sbjct: 350 PAPTTPKEPAPTTPKEPTPTT----------PKEPAPTTKEPAPTTPKEPAPTAPKKPAP 399
Query: 325 ASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQ 384
+P P P P PA T ++P PAP + P+ T T+ T E
Sbjct: 400 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 459
Query: 385 DPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPG 444
P + P +P P + + P A +P
Sbjct: 460 SPTTTK-EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 518
Query: 445 EPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPS 504
P+ET T P++ P P + L+ + P + + P + +
Sbjct: 519 TPKETAPTT----PKKLTPTTPEK-------LAPTTPEKPAPTTPEELAPTTPEEPTPTT 567
Query: 505 VRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEA--SSVGGPD 562
+P P+ ++ P P P EP P P PA E ++ G
Sbjct: 568 PEEPAPTTPKAAAPNTP-------KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 620
Query: 563 QARYLESAPGWPVGQEEWGVAHTSS-PPSTQTLSLWAPT 600
E AP P +A T++ P++ T APT
Sbjct: 621 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 659
Score = 56.2 bits (134), Expect = 9e-08
Identities = 69/316 (21%), Positives = 103/316 (32%), Gaps = 37/316 (11%)
Query: 273 AKPARRGQTSASILPRVVQAQRGPQPPPGEAGI-PGHPTPPA-----TLPSEPV----EG 322
AKP + +T+ + P P A P PTP T P EP +
Sbjct: 236 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 295
Query: 323 VQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRP 382
+P P P PA T P ++ PAP + P+ T + P
Sbjct: 296 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 355
Query: 383 EQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRS 442
++ +P P + P P EP + + P + + + +
Sbjct: 356 KEPAPTTPKEP------TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 409
Query: 443 PGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFST 502
P EP T + ++ P P+E A P+ P + PA T S
Sbjct: 410 PKEPAPTTT-------KEPSPTTPKEPA----------PTTTKSAPTTTKEPAPTTTKSA 452
Query: 503 PSV-RQPDPSAWLSSGPELTGMPR-VRLAAPLAVLPMEPLPPEPVRPAALLT--PEASSV 558
P+ ++P P+ P P P P EP P P PA T P ++
Sbjct: 453 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP 512
Query: 559 GGPDQARYLESAPGWP 574
P E+AP P
Sbjct: 513 KEPAPTTPKETAPTTP 528
Score = 56.2 bits (134), Expect = 9e-08
Identities = 94/477 (19%), Positives = 145/477 (30%), Gaps = 49/477 (10%)
Query: 203 TEPPASTAALRTTPSPPSPGPETPPAGVP---------------------PAASSQVWA- 240
T+ PA T +P P P TP P PA +++ A
Sbjct: 324 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 383
Query: 241 -----AGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRG 295
P A + + P+ K+ + P + + + +
Sbjct: 384 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 443
Query: 296 PQPPPGEAG--IPGHPTPPAT---LPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASS 350
P P ++ P P+P T P+ P E +P +P P P PA T P ++
Sbjct: 444 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 503
Query: 351 PSPPAP-RPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEP 409
PAP P+ P + T + L PE+ +P P EP
Sbjct: 504 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 563
Query: 410 IMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREG 469
P + + A P A +P P+E T P++T P P+
Sbjct: 564 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT----PKETAPTTPKGT 619
Query: 470 ARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLA 529
A L P+ + + P ++ + +P P+ + P
Sbjct: 620 A--PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP-------K 670
Query: 530 APLAVLPMEPLP--PEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSS 587
P P EP P P+ P L P ++ P + P A T+
Sbjct: 671 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 730
Query: 588 PPSTQTLSLW-APTGVLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPPEL 643
+ T APT P+ E P S EPT + PEL
Sbjct: 731 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 787
Score = 52.8 bits (125), Expect = 1e-06
Identities = 62/268 (23%), Positives = 87/268 (32%), Gaps = 38/268 (14%)
Query: 204 EPPAST---AALRTTPSPPSPGPETPPAGVPPA--ASSQVWAAGPAAQEWLSRDLLHRPS 258
E PA T AA TP P+P PA P A + P + + L P+
Sbjct: 569 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 628
Query: 259 DALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSE 318
KK PA P+ + +P P TP T P+
Sbjct: 629 PTTPKK----------PA----------PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 668
Query: 319 PVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLG 378
P E +P P P P A T ++P PAP+ P + GP+ T ++
Sbjct: 669 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKGPTSTTSDKPA 726
Query: 379 TVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELV 438
P++ +P P ++ AP P SE P T E
Sbjct: 727 PTTPKETAPTTPKEP----APTTPKKPAPTTPETPPPTTSEVSTP-------TTTKEPTT 775
Query: 439 SHRSPGEPQETCSGTEVERPRQTGPGLP 466
H+SP E S + + P P
Sbjct: 776 IHKSPDESTPELSAEPTPKALENSPKEP 803
Score = 40.8 bits (94), Expect = 0.004
Identities = 67/356 (18%), Positives = 111/356 (31%), Gaps = 31/356 (8%)
Query: 202 GTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDAL 261
GT P TTP P+P P P +++ +P+
Sbjct: 618 GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT-----------------CDKPAPT- 659
Query: 262 AKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVE 321
KG P + A P+ +P P P P P P+
Sbjct: 660 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKG 716
Query: 322 GVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAP-RPERPESLLVSGPSVTLTEGLGTV 380
+ +P P P A T P ++P PAP PE P + T T+ T+
Sbjct: 717 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 776
Query: 381 RPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSH 440
D + S + A E EPG + + +P T A ++
Sbjct: 777 HKSPDESTPELS-------AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 829
Query: 441 RSPGEPQETCSGTEVERPRQTGPGLPREG-ARGHMDLSSSEPSQDIEGPGLSILPARDAT 499
P+ T + ++ + T E +S +QD ++ L
Sbjct: 830 DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 889
Query: 500 FSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPE-PVRPAALLTPE 554
+ ++ + + + PE T P+ R A P P + P +P + P+
Sbjct: 890 PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPK 945
Score = 35.0 bits (79), Expect = 0.22
Identities = 44/205 (21%), Positives = 68/205 (33%), Gaps = 26/205 (12%)
Query: 413 EPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARG 472
E +++E Q + + LA V + + + T G + P++ P P+E A
Sbjct: 209 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA-- 266
Query: 473 HMDLSSSEPSQDI--EGPGLSILPARDATFSTP---------SVRQPDPSAWLSSGPELT 521
+ EP+ P PA T S P + ++P P+ P T
Sbjct: 267 --STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 324
Query: 522 GMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWG 581
P P EP P P +PA E + + P P
Sbjct: 325 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-----------PTTPKEPTPTTPKE 373
Query: 582 VAHTSSPPSTQTLSLWAPTGVLLPS 606
A T+ P+ T APT P+
Sbjct: 374 PAPTTKEPAPTTPKEPAPTAPKKPA 398
>gi|189181720 proteoglycan 4 isoform B [Homo sapiens]
Length = 1363
Score = 66.2 bits (160), Expect = 9e-11
Identities = 90/385 (23%), Positives = 126/385 (32%), Gaps = 45/385 (11%)
Query: 206 PASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKG 265
PAST TP+ P TP P S P + + P+ K+
Sbjct: 317 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKS-----APTTPKEPAPTTTKEPAPTTPKEP 371
Query: 266 LGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPT---PPATLPSEPV-- 320
T +PA SA P+ +P P P T P T P EP
Sbjct: 372 AP--TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 429
Query: 321 --EGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAP-RPERPESLLVSGPSVTLTEGL 377
E +P P P P PA T P ++P PAP + P P+ T T+
Sbjct: 430 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 489
Query: 378 GTVRPEQDPAKSPGSPLLLRGLSSGDVAAP------EPIMGEPGQASEEFQPLARPWRAT 431
T E P + +P + S P EP P + + P
Sbjct: 490 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 549
Query: 432 LAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLS 491
A +P P+E T P++T P P++ L+ + P +
Sbjct: 550 EPAPTTTKKPAPTTPKEPAPTT----PKETAPTTPKK-------LTPTTPEKLAPTTPEK 598
Query: 492 ILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAALL 551
P + + +P P+ PE + AAP P EP P P PA
Sbjct: 599 PAPTTPEELAPTTPEEPTPTT-----PEEPAPTTPKAAAPNT--PKEPAPTTPKEPAP-T 650
Query: 552 TPEASSVGGPDQARYLESAPGWPVG 576
TP+ + P E+AP P G
Sbjct: 651 TPKEPAPTTPK-----ETAPTTPKG 670
Score = 62.4 bits (150), Expect = 1e-09
Identities = 81/399 (20%), Positives = 126/399 (31%), Gaps = 33/399 (8%)
Query: 206 PASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHR-PSDALAKK 264
P +T + TTP P+P PA P + PA S + P+ KK
Sbjct: 342 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 401
Query: 265 GLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQ 324
+ P + + + P+ P P TP P+ P +
Sbjct: 402 PAPTTPKEPAPTTPKEPTPTT----------PKEPAPTTKEPAPTTPKEPAPTAPKKPAP 451
Query: 325 ASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQ 384
+P P P P PA T ++P PAP + P+ T T+ T E
Sbjct: 452 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 511
Query: 385 DPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPG 444
P + P +P P + + P A +P
Sbjct: 512 SPTTTK-EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 570
Query: 445 EPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPS 504
P+ET T P++ P P + L+ + P + + P + +
Sbjct: 571 TPKETAPTT----PKKLTPTTPEK-------LAPTTPEKPAPTTPEELAPTTPEEPTPTT 619
Query: 505 VRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEA--SSVGGPD 562
+P P+ ++ P P P EP P P PA E ++ G
Sbjct: 620 PEEPAPTTPKAAAPNTP-------KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 672
Query: 563 QARYLESAPGWPVGQEEWGVAHTSS-PPSTQTLSLWAPT 600
E AP P +A T++ P++ T APT
Sbjct: 673 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 711
Score = 56.2 bits (134), Expect = 9e-08
Identities = 69/316 (21%), Positives = 103/316 (32%), Gaps = 37/316 (11%)
Query: 273 AKPARRGQTSASILPRVVQAQRGPQPPPGEAGI-PGHPTPPA-----TLPSEPV----EG 322
AKP + +T+ + P P A P PTP T P EP +
Sbjct: 288 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 347
Query: 323 VQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRP 382
+P P P PA T P ++ PAP + P+ T + P
Sbjct: 348 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 407
Query: 383 EQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRS 442
++ +P P + P P EP + + P + + + +
Sbjct: 408 KEPAPTTPKEP------TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 461
Query: 443 PGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFST 502
P EP T + ++ P P+E A P+ P + PA T S
Sbjct: 462 PKEPAPTTT-------KEPSPTTPKEPA----------PTTTKSAPTTTKEPAPTTTKSA 504
Query: 503 PSV-RQPDPSAWLSSGPELTGMPR-VRLAAPLAVLPMEPLPPEPVRPAALLT--PEASSV 558
P+ ++P P+ P P P P EP P P PA T P ++
Sbjct: 505 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP 564
Query: 559 GGPDQARYLESAPGWP 574
P E+AP P
Sbjct: 565 KEPAPTTPKETAPTTP 580
Score = 56.2 bits (134), Expect = 9e-08
Identities = 94/477 (19%), Positives = 145/477 (30%), Gaps = 49/477 (10%)
Query: 203 TEPPASTAALRTTPSPPSPGPETPPAGVP---------------------PAASSQVWA- 240
T+ PA T +P P P TP P PA +++ A
Sbjct: 376 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 435
Query: 241 -----AGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRG 295
P A + + P+ K+ + P + + + +
Sbjct: 436 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 495
Query: 296 PQPPPGEAG--IPGHPTPPAT---LPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASS 350
P P ++ P P+P T P+ P E +P +P P P PA T P ++
Sbjct: 496 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 555
Query: 351 PSPPAP-RPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEP 409
PAP P+ P + T + L PE+ +P P EP
Sbjct: 556 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 615
Query: 410 IMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREG 469
P + + A P A +P P+E T P++T P P+
Sbjct: 616 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT----PKETAPTTPKGT 671
Query: 470 ARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLA 529
A L P+ + + P ++ + +P P+ + P
Sbjct: 672 A--PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP-------K 722
Query: 530 APLAVLPMEPLP--PEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSS 587
P P EP P P+ P L P ++ P + P A T+
Sbjct: 723 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 782
Query: 588 PPSTQTLSLW-APTGVLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPPEL 643
+ T APT P+ E P S EPT + PEL
Sbjct: 783 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 839
Score = 52.8 bits (125), Expect = 1e-06
Identities = 62/268 (23%), Positives = 87/268 (32%), Gaps = 38/268 (14%)
Query: 204 EPPAST---AALRTTPSPPSPGPETPPAGVPPA--ASSQVWAAGPAAQEWLSRDLLHRPS 258
E PA T AA TP P+P PA P A + P + + L P+
Sbjct: 621 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 680
Query: 259 DALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSE 318
KK PA P+ + +P P TP T P+
Sbjct: 681 PTTPKK----------PA----------PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 720
Query: 319 PVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLG 378
P E +P P P P A T ++P PAP+ P + GP+ T ++
Sbjct: 721 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKGPTSTTSDKPA 778
Query: 379 TVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELV 438
P++ +P P ++ AP P SE P T E
Sbjct: 779 PTTPKETAPTTPKEP----APTTPKKPAPTTPETPPPTTSEVSTP-------TTTKEPTT 827
Query: 439 SHRSPGEPQETCSGTEVERPRQTGPGLP 466
H+SP E S + + P P
Sbjct: 828 IHKSPDESTPELSAEPTPKALENSPKEP 855
Score = 40.8 bits (94), Expect = 0.004
Identities = 67/356 (18%), Positives = 111/356 (31%), Gaps = 31/356 (8%)
Query: 202 GTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDAL 261
GT P TTP P+P P P +++ +P+
Sbjct: 670 GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT-----------------CDKPAPT- 711
Query: 262 AKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVE 321
KG P + A P+ +P P P P P P+
Sbjct: 712 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKG 768
Query: 322 GVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAP-RPERPESLLVSGPSVTLTEGLGTV 380
+ +P P P A T P ++P PAP PE P + T T+ T+
Sbjct: 769 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 828
Query: 381 RPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSH 440
D + S + A E EPG + + +P T A ++
Sbjct: 829 HKSPDESTPELS-------AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 881
Query: 441 RSPGEPQETCSGTEVERPRQTGPGLPREG-ARGHMDLSSSEPSQDIEGPGLSILPARDAT 499
P+ T + ++ + T E +S +QD ++ L
Sbjct: 882 DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 941
Query: 500 FSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPE-PVRPAALLTPE 554
+ ++ + + + PE T P+ R A P P + P +P + P+
Sbjct: 942 PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPK 997
Score = 35.0 bits (79), Expect = 0.22
Identities = 44/205 (21%), Positives = 68/205 (33%), Gaps = 26/205 (12%)
Query: 413 EPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARG 472
E +++E Q + + LA V + + + T G + P++ P P+E A
Sbjct: 261 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA-- 318
Query: 473 HMDLSSSEPSQDI--EGPGLSILPARDATFSTP---------SVRQPDPSAWLSSGPELT 521
+ EP+ P PA T S P + ++P P+ P T
Sbjct: 319 --STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 376
Query: 522 GMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWG 581
P P EP P P +PA E + + P P
Sbjct: 377 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-----------PTTPKEPTPTTPKE 425
Query: 582 VAHTSSPPSTQTLSLWAPTGVLLPS 606
A T+ P+ T APT P+
Sbjct: 426 PAPTTKEPAPTTPKEPAPTAPKKPA 450
>gi|67190163 proteoglycan 4 isoform A [Homo sapiens]
Length = 1404
Score = 66.2 bits (160), Expect = 9e-11
Identities = 90/385 (23%), Positives = 126/385 (32%), Gaps = 45/385 (11%)
Query: 206 PASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKG 265
PAST TP+ P TP P S P + + P+ K+
Sbjct: 358 PASTTPKEPTPTTIKSAPTTPKEPAPTTTKS-----APTTPKEPAPTTTKEPAPTTPKEP 412
Query: 266 LGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPT---PPATLPSEPV-- 320
T +PA SA P+ +P P P T P T P EP
Sbjct: 413 AP--TTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPT 470
Query: 321 --EGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAP-RPERPESLLVSGPSVTLTEGL 377
E +P P P P PA T P ++P PAP + P P+ T T+
Sbjct: 471 TKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSA 530
Query: 378 GTVRPEQDPAKSPGSPLLLRGLSSGDVAAP------EPIMGEPGQASEEFQPLARPWRAT 431
T E P + +P + S P EP P + + P
Sbjct: 531 PTTTKEPAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPK 590
Query: 432 LAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLS 491
A +P P+E T P++T P P++ L+ + P +
Sbjct: 591 EPAPTTTKKPAPTTPKEPAPTT----PKETAPTTPKK-------LTPTTPEKLAPTTPEK 639
Query: 492 ILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAALL 551
P + + +P P+ PE + AAP P EP P P PA
Sbjct: 640 PAPTTPEELAPTTPEEPTPTT-----PEEPAPTTPKAAAPNT--PKEPAPTTPKEPAP-T 691
Query: 552 TPEASSVGGPDQARYLESAPGWPVG 576
TP+ + P E+AP P G
Sbjct: 692 TPKEPAPTTPK-----ETAPTTPKG 711
Score = 62.4 bits (150), Expect = 1e-09
Identities = 81/399 (20%), Positives = 126/399 (31%), Gaps = 33/399 (8%)
Query: 206 PASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHR-PSDALAKK 264
P +T + TTP P+P PA P + PA S + P+ KK
Sbjct: 383 PTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKK 442
Query: 265 GLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQ 324
+ P + + + P+ P P TP P+ P +
Sbjct: 443 PAPTTPKEPAPTTPKEPTPTT----------PKEPAPTTKEPAPTTPKEPAPTAPKKPAP 492
Query: 325 ASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQ 384
+P P P P PA T ++P PAP + P+ T T+ T E
Sbjct: 493 TTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKEPAPTTTKSAPTTPKEP 552
Query: 385 DPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPG 444
P + P +P P + + P A +P
Sbjct: 553 SPTTTK-EPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTPKEPAPT 611
Query: 445 EPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPS 504
P+ET T P++ P P + L+ + P + + P + +
Sbjct: 612 TPKETAPTT----PKKLTPTTPEK-------LAPTTPEKPAPTTPEELAPTTPEEPTPTT 660
Query: 505 VRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEA--SSVGGPD 562
+P P+ ++ P P P EP P P PA E ++ G
Sbjct: 661 PEEPAPTTPKAAAPNTP-------KEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTA 713
Query: 563 QARYLESAPGWPVGQEEWGVAHTSS-PPSTQTLSLWAPT 600
E AP P +A T++ P++ T APT
Sbjct: 714 PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPT 752
Score = 56.2 bits (134), Expect = 9e-08
Identities = 69/316 (21%), Positives = 103/316 (32%), Gaps = 37/316 (11%)
Query: 273 AKPARRGQTSASILPRVVQAQRGPQPPPGEAGI-PGHPTPPA-----TLPSEPV----EG 322
AKP + +T+ + P P A P PTP T P EP +
Sbjct: 329 AKPTPKAETTTKGPALTTPKEPTPTTPKEPASTTPKEPTPTTIKSAPTTPKEPAPTTTKS 388
Query: 323 VQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRP 382
+P P P PA T P ++ PAP + P+ T + P
Sbjct: 389 APTTPKEPAPTTTKEPAPTTPKEPAPTTTKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTP 448
Query: 383 EQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRS 442
++ +P P + P P EP + + P + + + +
Sbjct: 449 KEPAPTTPKEP------TPTTPKEPAPTTKEPAPTTPKEPAPTAPKKPAPTTPKEPAPTT 502
Query: 443 PGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFST 502
P EP T + ++ P P+E A P+ P + PA T S
Sbjct: 503 PKEPAPTTT-------KEPSPTTPKEPA----------PTTTKSAPTTTKEPAPTTTKSA 545
Query: 503 PSV-RQPDPSAWLSSGPELTGMPR-VRLAAPLAVLPMEPLPPEPVRPAALLT--PEASSV 558
P+ ++P P+ P P P P EP P P PA T P ++
Sbjct: 546 PTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTTTKKPAPTTP 605
Query: 559 GGPDQARYLESAPGWP 574
P E+AP P
Sbjct: 606 KEPAPTTPKETAPTTP 621
Score = 56.2 bits (134), Expect = 9e-08
Identities = 94/477 (19%), Positives = 145/477 (30%), Gaps = 49/477 (10%)
Query: 203 TEPPASTAALRTTPSPPSPGPETPPAGVP---------------------PAASSQVWA- 240
T+ PA T +P P P TP P PA +++ A
Sbjct: 417 TKEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPTPTTPKEPAPTTKEPAP 476
Query: 241 -----AGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRG 295
P A + + P+ K+ + P + + + +
Sbjct: 477 TTPKEPAPTAPKKPAPTTPKEPAPTTPKEPAPTTTKEPSPTTPKEPAPTTTKSAPTTTKE 536
Query: 296 PQPPPGEAG--IPGHPTPPAT---LPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASS 350
P P ++ P P+P T P+ P E +P +P P P PA T P ++
Sbjct: 537 PAPTTTKSAPTTPKEPSPTTTKEPAPTTPKEPAPTTPKKPAPTTPKEPAPTTPKEPAPTT 596
Query: 351 PSPPAP-RPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEP 409
PAP P+ P + T + L PE+ +P P EP
Sbjct: 597 TKKPAPTTPKEPAPTTPKETAPTTPKKLTPTTPEKLAPTTPEKPAPTTPEELAPTTPEEP 656
Query: 410 IMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREG 469
P + + A P A +P P+E T P++T P P+
Sbjct: 657 TPTTPEEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTT----PKETAPTTPKGT 712
Query: 470 ARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLA 529
A L P+ + + P ++ + +P P+ + P
Sbjct: 713 A--PTTLKEPAPTTPKKPAPKELAPTTTKEPTSTTCDKPAPTTPKGTAPTTP-------K 763
Query: 530 APLAVLPMEPLP--PEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSS 587
P P EP P P+ P L P ++ P + P A T+
Sbjct: 764 EPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTTTKGPTSTTSDKPAPTTP 823
Query: 588 PPSTQTLSLW-APTGVLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPPEL 643
+ T APT P+ E P S EPT + PEL
Sbjct: 824 KETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTIHKSPDESTPEL 880
Score = 52.8 bits (125), Expect = 1e-06
Identities = 62/268 (23%), Positives = 87/268 (32%), Gaps = 38/268 (14%)
Query: 204 EPPAST---AALRTTPSPPSPGPETPPAGVPPA--ASSQVWAAGPAAQEWLSRDLLHRPS 258
E PA T AA TP P+P PA P A + P + + L P+
Sbjct: 662 EEPAPTTPKAAAPNTPKEPAPTTPKEPAPTTPKEPAPTTPKETAPTTPKGTAPTTLKEPA 721
Query: 259 DALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSE 318
KK PA P+ + +P P TP T P+
Sbjct: 722 PTTPKK----------PA----------PKELAPTTTKEPTSTTCDKPAPTTPKGTAPTT 761
Query: 319 PVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLG 378
P E +P P P P A T ++P PAP+ P + GP+ T ++
Sbjct: 762 PKEPAPTTPKEPAPTTPKGTAPTTLKEPAPTTPKKPAPKELAPTT--TKGPTSTTSDKPA 819
Query: 379 TVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELV 438
P++ +P P ++ AP P SE P T E
Sbjct: 820 PTTPKETAPTTPKEP----APTTPKKPAPTTPETPPPTTSEVSTP-------TTTKEPTT 868
Query: 439 SHRSPGEPQETCSGTEVERPRQTGPGLP 466
H+SP E S + + P P
Sbjct: 869 IHKSPDESTPELSAEPTPKALENSPKEP 896
Score = 40.8 bits (94), Expect = 0.004
Identities = 67/356 (18%), Positives = 111/356 (31%), Gaps = 31/356 (8%)
Query: 202 GTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDAL 261
GT P TTP P+P P P +++ +P+
Sbjct: 711 GTAPTTLKEPAPTTPKKPAPKELAPTTTKEPTSTT-----------------CDKPAPT- 752
Query: 262 AKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVE 321
KG P + A P+ +P P P P P P+
Sbjct: 753 TPKGTAPTTPKEPAPTTPKEPAPTTPKGTAPTTLKEPAP---TTPKKPAPKELAPTTTKG 809
Query: 322 GVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAP-RPERPESLLVSGPSVTLTEGLGTV 380
+ +P P P A T P ++P PAP PE P + T T+ T+
Sbjct: 810 PTSTTSDKPAPTTPKETAPTTPKEPAPTTPKKPAPTTPETPPPTTSEVSTPTTTKEPTTI 869
Query: 381 RPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSH 440
D + S + A E EPG + + +P T A ++
Sbjct: 870 HKSPDESTPELS-------AEPTPKALENSPKEPGVPTTKTPAATKPEMTTTAKDKTTER 922
Query: 441 RSPGEPQETCSGTEVERPRQTGPGLPREG-ARGHMDLSSSEPSQDIEGPGLSILPARDAT 499
P+ T + ++ + T E +S +QD ++ L
Sbjct: 923 DLRTTPETTTAAPKMTKETATTTEKTTESKITATTTQVTSTTTQDTTPFKITTLKTTTLA 982
Query: 500 FSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPE-PVRPAALLTPE 554
+ ++ + + + PE T P+ R A P P + P +P + P+
Sbjct: 983 PKVTTTKKTITTTEIMNKPEETAKPKDRATNSKATTPKPQKPTKAPKKPTSTKKPK 1038
Score = 35.0 bits (79), Expect = 0.22
Identities = 44/205 (21%), Positives = 68/205 (33%), Gaps = 26/205 (12%)
Query: 413 EPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARG 472
E +++E Q + + LA V + + + T G + P++ P P+E A
Sbjct: 302 EKTTSAKETQSIEKTSAKDLAPTSKVLAKPTPKAETTTKGPALTTPKEPTPTTPKEPA-- 359
Query: 473 HMDLSSSEPSQDI--EGPGLSILPARDATFSTP---------SVRQPDPSAWLSSGPELT 521
+ EP+ P PA T S P + ++P P+ P T
Sbjct: 360 --STTPKEPTPTTIKSAPTTPKEPAPTTTKSAPTTPKEPAPTTTKEPAPTTPKEPAPTTT 417
Query: 522 GMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWG 581
P P EP P P +PA E + + P P
Sbjct: 418 KEPAPTTTKSAPTTPKEPAPTTPKKPAPTTPKEPA-----------PTTPKEPTPTTPKE 466
Query: 582 VAHTSSPPSTQTLSLWAPTGVLLPS 606
A T+ P+ T APT P+
Sbjct: 467 PAPTTKEPAPTTPKEPAPTAPKKPA 491
>gi|149773456 hypothetical protein LOC643314 [Homo sapiens]
Length = 1427
Score = 65.9 bits (159), Expect = 1e-10
Identities = 94/397 (23%), Positives = 136/397 (34%), Gaps = 46/397 (11%)
Query: 199 VGSGTEPPASTAALRTTPSPPSPG--------PETPPAGVPPAAS-SQVWAAGPAAQEWL 249
V + EP + AA+ T P SP P +P A VPP + AA P +E
Sbjct: 994 VSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPPPEEPTSPAAAVPTPEEPT 1053
Query: 250 SRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHP 309
S P+ A+ A P TS + V P P P P
Sbjct: 1054 S------PAAAVPTPEEPTSPAAAVPTPEEPTSPA---AAVPTPEEPTSPAAAVPTPEEP 1104
Query: 310 TPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGP 369
T PA P E + P P P PA +P + + P+P P PE S V+ P
Sbjct: 1105 TSPAAAVPTPEEPASPAAAVPTPEEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVP 1164
Query: 370 SVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWR 429
T E PA+S ++ L + +P + P + P
Sbjct: 1165 --TPEESASPAAAVPTPAESASFAAVVATLE--EPTSPAASVPTPAAMVATLEEFTSPAA 1220
Query: 430 ATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPG 489
+ +EE S + E + P P +LSS P+ + P
Sbjct: 1221 SVPTSEEPASLAAAVSNPEEPTSPAAAVPTLEEPTSSAAAVLTPEELSS--PAASVPTPE 1278
Query: 490 LSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAA 549
PA + ++ +P A PE+ +P + P P P PAA
Sbjct: 1279 EPASPAA----AVSNLEEPASPAAAVPTPEVAAIPAASV----------PTPEVPAIPAA 1324
Query: 550 LLTP--EASSVGGP--DQARYLESAP----GWPVGQE 578
+ P E S +G P + + +S P G PV +E
Sbjct: 1325 AVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLEE 1361
Score = 64.3 bits (155), Expect = 3e-10
Identities = 105/484 (21%), Positives = 159/484 (32%), Gaps = 70/484 (14%)
Query: 206 PASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEW--LSRDLLHRPSDALAK 263
P TAA+ SP ET PA + A + EW L+ + D +
Sbjct: 917 PEGTAAVAAVSSPE----ETAPAVAAAITQEGMSAVAGFSPEWAALAITVPITEEDGTPE 972
Query: 264 KGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGV 323
+ P P + V P P P PT PA P E
Sbjct: 973 GPVTPATTVHAPEEPDTAAVR-----VSTPEEPASPAAAVPTPEEPTSPAAAVPTPEEPT 1027
Query: 324 QASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPE 383
+ P P PT PA +P + +SP+ P PE P S + P+ P
Sbjct: 1028 SPAAAVPPPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPTPEEPTSPAAAVPT 1087
Query: 384 QDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSP 443
+ SP + A P P E P A A + +P
Sbjct: 1088 PEEPTSPAA------------AVPTP--------EEPTSPAAAVPTPEEPASPAAAVPTP 1127
Query: 444 GEPQETCSGTEV-ERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATF-- 500
EP + E P P +P ++ P + PA A+F
Sbjct: 1128 EEPASPAAAVPTPEEPAFPAPAVPTPEESASAAVAVPTPEESASPAAAVPTPAESASFAA 1187
Query: 501 --------STPSVRQPDPSAWLSSGPELT----GMPRVRLAAPLAVL---PMEPLPPEPV 545
++P+ P P+A +++ E T +P A LA P EP P
Sbjct: 1188 VVATLEEPTSPAASVPTPAAMVATLEEFTSPAASVPTSEEPASLAAAVSNPEEPTSPAAA 1247
Query: 546 RP---------AALLTPE-----ASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPST 591
P AA+LTPE A+SV P++ ++P V E + ++ P+
Sbjct: 1248 VPTLEEPTSSAAAVLTPEELSSPAASVPTPEE----PASPAAAVSNLEEPASPAAAVPTP 1303
Query: 592 QTLSLWAPTGVLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPPELQDSVEGLS 651
+ ++ A + +P+ P A + P L +SA + P ++ L
Sbjct: 1304 EVAAIPAAS---VPTPEVPAIPAAAVPPMEEVSPIGVPFLGVSAHTDSVPISEEGTPVLE 1360
Query: 652 ERPS 655
E S
Sbjct: 1361 EASS 1364
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 65.5 bits (158), Expect = 2e-10
Identities = 125/496 (25%), Positives = 171/496 (34%), Gaps = 93/496 (18%)
Query: 200 GSGTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSD 259
G+ PA+ A TP PP G PP V PAA + AAG ++ L+
Sbjct: 11 GAAARTPAARAPGLLTPRPP--GSPRPPPPVTPAALRVLGAAGAVGRKPLAE-------- 60
Query: 260 ALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEP 319
G+G R G T ++ A R P GE P T P + S
Sbjct: 61 --RAGGIGGATIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAKNTSPGPVSSP- 117
Query: 320 VEGVQASPWRPRPV--------------------LPTHPALTLPVSSDASSPSPPAPRPE 359
G + RP P+ P AL+ D S P+P P P
Sbjct: 118 --GRASGTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSGPTPGTPSPA 175
Query: 360 RPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASE 419
+G V L + RP + P + P + S+ + + EP
Sbjct: 176 MARRSRAAGTEVGLPRPAPSARP-RPPTEGPRKSV----SSASEHSTTEP---------- 220
Query: 420 EFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGP---GLPREGARGHM-- 474
P AR R A L + P + S T + P ++GP G PR A
Sbjct: 221 --SPAAR--RRPSAGGGL---QRPASRSLSSSATPLSSPARSGPSARGTPRAPAHPSQPK 273
Query: 475 --DLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSS--GPELTGMPR----- 525
L + P Q + P PA S+P + P PSA L S P L P
Sbjct: 274 PKGLQALRPPQ-VTPPRKDAAPALGPLSSSP-LATPSPSAALQSQAPPTLPATPHSSSLT 331
Query: 526 VRLAAPLAVLPMEPLPPE-----PVRPAALLTPEASSVGGPD-QA--RYLESAP----GW 573
+LA PL + P P P P PA + +S+G P QA +L S P
Sbjct: 332 CQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 391
Query: 574 PVGQEEWGVA-----HTSSPPSTQTLSLWAPTGVLLPSLVE---LEYPFQAGRGASLQQE 625
P Q +A SPP++ LS A P+ + L+ PF +Q
Sbjct: 392 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAP 451
Query: 626 LTEPTLALSAESHRPP 641
+ P + S PP
Sbjct: 452 FSPPASPPVSPSATPP 467
Score = 65.5 bits (158), Expect = 2e-10
Identities = 109/399 (27%), Positives = 138/399 (34%), Gaps = 87/399 (21%)
Query: 203 TEPPASTAA--LRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDA 260
++ P S AA L+ PSPP+ P +P A PP A + A
Sbjct: 468 SQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAA-------------------- 507
Query: 261 LAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHP--TPPATLPSE 318
P LQ AKP + + + P Q P PP A PG +P A+LP
Sbjct: 508 -------PPLQLAKPPPQAPPALATPP----LQALPSPP---ASFPGQAPFSPSASLPMS 553
Query: 319 PVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPR--PERPESLLVSGPSVTLTEG 376
P+ A+P P + P L +P S A SP+ APR P VSGP +TL
Sbjct: 554 PL----ATPPPQAPPVLAAPLLQVPPSPPA-SPTLQAPRRPPTPGPDTSVSGPRLTLALA 608
Query: 377 LGTVRPEQDPAKSPGSPLL---LRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLA 433
G P P++SP S L L G SS + PE + G P A
Sbjct: 609 PG---PPPPPSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAA 665
Query: 434 AEELVSHRSPGEPQ--ETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLS 491
R P P G + P TGPG A G + + EGP
Sbjct: 666 CHPAAWSRGPAPPLAFRGAPGAPLPWPPATGPG----SADGLCTI------YETEGP--- 712
Query: 492 ILPARDATFSTPSVRQPDPSAWLSSGPELTG-----MPRVRLAAPLAVLPMEPLPPEPVR 546
++ P P PS S G G R A L LP+ L V+
Sbjct: 713 -----ESATPAPGALDPGPSPGTSGGKAAAGAGAGASSRSPKQARLGELPLGALQASVVQ 767
Query: 547 ---PAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGV 582
LL A G + G P G E GV
Sbjct: 768 HLLSRTLLLAAAEGAAG--------GSGGGPGGAEGGGV 798
Score = 54.7 bits (130), Expect = 3e-07
Identities = 113/468 (24%), Positives = 153/468 (32%), Gaps = 72/468 (15%)
Query: 206 PASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKG 265
P++ +L+T PSPP+ TPP+ + S A + L P
Sbjct: 345 PSAPPSLQTLPSPPA----TPPSQATTSLGSPTLQA--------THSFLPSP-------- 384
Query: 266 LGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQA 325
P A P + + ++ P + P PP + TP P+ +
Sbjct: 385 --PLSPLATPPPQAPPALALPPL-----QAPPSPPASPPLSPLATPSPQAPNALAVHLLQ 437
Query: 326 SPWRPRPVLPTH----PALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVR 381
+P+ P P P P + PVS A+ PS P P + P +
Sbjct: 438 APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATP 497
Query: 382 PEQDPAKSPGSPLLLR--------GLSSGDV-AAPEPIMGEPGQ------ASEEFQPLAR 426
P Q P PL L L++ + A P P PGQ AS PLA
Sbjct: 498 PPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLAT 557
Query: 427 P---WRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQ 483
P LAA L + P P + + RP GP G R + L+ P
Sbjct: 558 PPPQAPPVLAAPLL---QVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPPP 614
Query: 484 DIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPE----LTGMPRVRLAA-PLAVLPME 538
P ++ A S+ + P+ SGPE + P LAA A
Sbjct: 615 PSRSPSSTLSGPDLAGHSSSATSTPEELRGYDSGPEGGAAASPPPDAELAACHPAAWSRG 674
Query: 539 PLPPEPVR---PAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTLS 595
P PP R A L P A+ G D + G G P T
Sbjct: 675 PAPPLAFRGAPGAPLPWPPATGPGSADGLCTIYETEGPESATPAPGALDPGPSPGTSGGK 734
Query: 596 LWAPTGVLLPSLVELEYPFQAGRG--------ASLQQELTEPTLALSA 635
A G S P QA G AS+ Q L TL L+A
Sbjct: 735 AAAGAGAGASS----RSPKQARLGELPLGALQASVVQHLLSRTLLLAA 778
>gi|47132519 Ras association and pleckstrin homology domains 1 isoform
1 [Homo sapiens]
Length = 1250
Score = 65.1 bits (157), Expect = 2e-10
Identities = 107/469 (22%), Positives = 157/469 (33%), Gaps = 68/469 (14%)
Query: 216 PSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKP 275
P PP P P PP PP S +AG AA ++ + R +A G F P
Sbjct: 632 PPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSG-ALFKPPTPP 690
Query: 276 ARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVLP 335
+ Q S+ P+++ G PPP P P P P G + +P P P
Sbjct: 691 VMQSQ---SVKPQILVPPNGVVPPP--------PPP----PPPPTPGSAMAQLKPAPCAP 735
Query: 336 THPALTLP--------------VSSDASSPSPPAPR---PERPESLLVSGPSVTLTEGLG 378
+ P + P V+ P PP P P+ P LV+ P+ T T+ +
Sbjct: 736 SLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVA 795
Query: 379 ---------TVRPEQDPA-KSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPW 428
T P PA K P P S P P P Q S +P P
Sbjct: 796 PVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPL 855
Query: 429 RATLAAEELVSHRSPGEPQETCSGTEVERP---RQTGPGLPREGARGHMDLSS-SEPSQD 484
+ + ++ + P P ++ +P P A+ SS PS D
Sbjct: 856 SPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPD 915
Query: 485 IEGPGLSILPARDATFSTP-----SVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEP 539
P P F P P P S P+ +G P + + + +P
Sbjct: 916 FPPPP----PESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKP 971
Query: 540 LPPEPVRPAALLTPEASSVGGPDQ-------ARYLESAPGWPVGQEEWGVAHTSSPPSTQ 592
PP P R +++ + + P + +++ A +E P
Sbjct: 972 -PPTPQRNSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKL 1030
Query: 593 TLSLWAPTGVLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPP 641
LS GVL V + P +GRG E P ++S PP
Sbjct: 1031 NLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSP----PSDSDFPP 1075
Score = 43.9 bits (102), Expect = 5e-04
Identities = 77/343 (22%), Positives = 110/343 (32%), Gaps = 56/343 (16%)
Query: 203 TEPPASTAALRTTPSPPSPGPETPPAGVPPA-ASSQVWAAGPAAQEWLSRDLLHRPSDAL 261
T P T A TP+PP PPA PA +S + + P + L +
Sbjct: 793 TVAPVVTQAAPPTPTPP-----VPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFC 847
Query: 262 AKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVE 321
AK P S++ ++ P PP P P P P P
Sbjct: 848 AKPPPSPL----------SPVPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSP-P 896
Query: 322 GVQASP-WRPR---------PVLPTHPALTLPVSSDASSPSPPAPRP----ERPESLLVS 367
V+A P W+P P P +L P + P+PP P P P+
Sbjct: 897 AVKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSP 956
Query: 368 GPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARP 427
G + T G +P P ++ SS PEP +F P A
Sbjct: 957 GKKTSKTSSPGGKKPPPTPQRNSSIK------SSSGAEHPEPKRPSVDSLVSKFTPPAE- 1009
Query: 428 WRATLAAEELVSHRSPGEPQE-TCSGTEVERPRQTG------PGLPREGARGHMDLSSSE 480
+ + E L +P +P + SG + Q G P L G ++ S
Sbjct: 1010 -SGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPP 1068
Query: 481 PSQDIEGPGLSI--------LPARDATFSTPSVR--QPDPSAW 513
D P +PA + ++P V P P W
Sbjct: 1069 SDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQW 1111
Score = 33.9 bits (76), Expect = 0.49
Identities = 59/256 (23%), Positives = 80/256 (31%), Gaps = 44/256 (17%)
Query: 332 PVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPG 391
P L P + P + AS PSPP P P P P P P
Sbjct: 607 PPLSPQPKIVTPYT--ASQPSPPLPPPPPPPP------------------PPPPPPPPPP 646
Query: 392 SPLLLRGLSSGDVAAPEPI----MGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQ 447
PL + S AAP + + AS+ L +P + + V +PQ
Sbjct: 647 PPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSV------KPQ 700
Query: 448 ETCSGTEVERPRQTGPGLPREGAR----GHMDLSSSEPSQDIEGPGLSILPARDATFSTP 503
V P P P G+ + S P P L I + T P
Sbjct: 701 ILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAP 760
Query: 504 SVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPL-----PPEPVRPAALLTPEASSV 558
P P P+ P V + AP + + P+ PP P P + P
Sbjct: 761 PTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPP---VPPAKKQP 817
Query: 559 GGPDQARYLESAPGWP 574
P A Y+ +P P
Sbjct: 818 AFP--ASYIPPSPPTP 831
Score = 33.9 bits (76), Expect = 0.49
Identities = 51/236 (21%), Positives = 82/236 (34%), Gaps = 60/236 (25%)
Query: 205 PPASTAALRTTPSPPSPGPETPP------------AGVPPAASSQVWAAG---------- 242
PP ++L P PPSP P PP +G P +S+ + G
Sbjct: 918 PPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPTPQR 977
Query: 243 -----------------PAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASI 285
P+ +S+ S + +K+ L P KP + + +
Sbjct: 978 NSSIKSSSGAEHPEPKRPSVDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVN- 1036
Query: 286 LPRVVQ-----------AQRGPQ------PPPGEAGIPGHPTPPAT-LPSEPVEGVQASP 327
LP V+Q + RG PP ++ P P PP T LP P+E
Sbjct: 1037 LPGVLQQGCVSAKAPVLSGRGKDSVVEFPSPPSDSDFP--PPPPETELPLPPIEIPAVFS 1094
Query: 328 WRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPE 383
P + S + +PP RP+R +S ++ ++ + TV P+
Sbjct: 1095 GNTSPKVAVVNPQPQQWSKMSVKKAPPPTRPKRNDSTRLTQAEISEQPTMATVVPQ 1150
Score = 33.1 bits (74), Expect = 0.83
Identities = 61/244 (25%), Positives = 86/244 (35%), Gaps = 58/244 (23%)
Query: 192 VESFFQCVGSGTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSR 251
V S + + S PP + A+ + P P P P + PPA A +W
Sbjct: 858 VPSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQS--PPAVK--------AKPKW--- 904
Query: 252 DLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTP 311
+PS P P ++S P PPP P P P
Sbjct: 905 ----QPSSI-------PVPSPDFPPPPPESSLVF----------PPPPPSPVPAPPPPPP 943
Query: 312 PATLPSEPVEG-------VQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERP--E 362
P P+ G +SP +P P SS SS P P+RP +
Sbjct: 944 PTASPTPDKSGSPGKKTSKTSSPGGKKP-----PPTPQRNSSIKSSSGAEHPEPKRPSVD 998
Query: 363 SLL--VSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRG------LSSGDVAAPEPIMGEP 414
SL+ + P+ + + T+ P P K PG L L G L G V+A P++
Sbjct: 999 SLVSKFTPPAESGSPSKETLPPPAAPPK-PGK-LNLSGVNLPGVLQQGCVSAKAPVLSGR 1056
Query: 415 GQAS 418
G+ S
Sbjct: 1057 GKDS 1060
Score = 31.6 bits (70), Expect = 2.4
Identities = 63/322 (19%), Positives = 108/322 (33%), Gaps = 58/322 (18%)
Query: 327 PWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERP---------ESLLVSGPSVTLTEGL 377
P P+P + T + P P PP P P P +S +G + +
Sbjct: 608 PLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKY 667
Query: 378 GTVRPEQDPAK------SPGSPLLLRGLS---------SGDV--AAPEPIMGEPGQASEE 420
T+ Q+ ++ P +P +++ S +G V P P PG A +
Sbjct: 668 STITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQ 727
Query: 421 FQPLARPWRATLAAEELVSHRSPGEP---------QETCSGTEVERPRQTGPGLPREGAR 471
+P A L +P P + T P P P+ +
Sbjct: 728 LKPAP-------CAPSLPQFSAPPPPLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPK 780
Query: 472 GHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPD-PSAWLSSGPELTGMPRVRLAA 530
+ + + ++ + P P+ +QP P++++ P +P
Sbjct: 781 PLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVP-----V 835
Query: 531 PLAVLPMEPL-----PPEPVRPAALLTPE-ASSVGGPDQARYLESAPGWPVGQEEWGVAH 584
P LP + PP P+ P + + AS P +ES P PV
Sbjct: 836 PPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLKPVPAN----VA 891
Query: 585 TSSPPSTQTLSLWAPTGVLLPS 606
SPP+ + W P+ + +PS
Sbjct: 892 PQSPPAVKAKPKWQPSSIPVPS 913
>gi|163914392 glioma tumor suppressor candidate region gene 1 [Homo
sapiens]
Length = 1560
Score = 62.4 bits (150), Expect = 1e-09
Identities = 118/467 (25%), Positives = 168/467 (35%), Gaps = 84/467 (17%)
Query: 185 AAPVLWTVESFFQCVGSGTEPPASTAA----LRTTPSPPSPGPETPPAGV--PPAASSQV 238
AAP+ + FQ P S AA ++ P+P P T GV PP+A + +
Sbjct: 544 AAPIQVGQPALFQM-------PVSLAAGSLPTQSQPAPAGPAATTVLQGVTLPPSAVAML 596
Query: 239 WAAGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASI-LPRVVQAQRGPQ 297
+ D L +P+ A G + T +PA + + S LP +Q + Q
Sbjct: 597 ----------NTPDGLVQPATPAAATGEAAPVLTVQPAPQAPPAVSTPLPLGLQQPQAQQ 646
Query: 298 PPPGEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPR 357
PP +A P PP +P G+ +SP + P T ++ D+ P R
Sbjct: 647 PP--QAPTPQAAAPPQATTPQPSPGLASSPEKIVLGQPPSATPTAILTQDSLQMFLPQER 704
Query: 358 PERPESLLVSGP--SVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPG 415
++P L GP SV + + P QDPA P +P + +G G A P
Sbjct: 705 SQQP--LSAEGPHLSVPASVIVSAPPPAQDPA--PATP-VAKGAGLGPQAPDSQASPAPA 759
Query: 416 QASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMD 475
PL P ++ SP P + P P LP
Sbjct: 760 PQIPAAAPLKGPGPSS----------SPSLPHQA--------PLGDSPHLP--------- 792
Query: 476 LSSSEPSQDIEGPGLSILPARDATFSTPSVRQP-DPSAWLSSGPELTGMPRVRLAAPLAV 534
S P++ P P+R + S P P P + P L G+ ++ +
Sbjct: 793 --SPHPTRPPSRP-----PSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIFVIQNQLGVPP 845
Query: 535 LPMEPLPPEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTL 594
P P P P L P++ GP L AP P VA +S S
Sbjct: 846 PASNPAPTAPGPPQPPLRPQSQPPEGP-----LPPAPHLPPSSTSSAVASSSETSS---- 896
Query: 595 SLWAPTGVLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPP 641
L APT PS +L++P G S PTL L E PP
Sbjct: 897 RLPAPT----PSDFQLQFPPSQGPHKS---PTPPPTLHLVPEPAAPP 936
Score = 43.5 bits (101), Expect = 6e-04
Identities = 112/464 (24%), Positives = 170/464 (36%), Gaps = 79/464 (17%)
Query: 200 GSGTEP--PASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRP 257
G G+ P PA L TP+P P PAGV P Q+ P A + + P
Sbjct: 330 GLGSSPLVPAPNVILHRTPTPIQP----KPAGVLPPKLYQL-TPKPFAPAGATLTIQGEP 384
Query: 258 SDALAKKGLGP----FLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPA 313
AL ++ P F+ K + S P +QA QPP G P PP
Sbjct: 385 G-ALPQQPKAPQNLTFMAAGKAGQNVVLSGFPAP-ALQANVFKQPPATTTG-AAPPQPPG 441
Query: 314 TLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPR--PERPESLLVSGPSV 371
L S+P +++ + + SS PA P + + LL P+V
Sbjct: 442 AL-SKP--------------------MSVHLLNQGSSIVIPAQHMLPGQNQFLLPGAPAV 480
Query: 372 TLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRAT 431
L + L + PA G L +G PI+ Q LA P
Sbjct: 481 QLPQQLSAL-----PANVGGQILAAAAPHTGGQLIANPILTN--------QNLAGP---- 523
Query: 432 LAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSS----SEPSQDIEG 487
L+ +++ S S ++ + +P A G + S + P+
Sbjct: 524 LSLGPVLAPHSGAHSAHILSAAPIQVGQPALFQMPVSLAAGSLPTQSQPAPAGPAATTVL 583
Query: 488 PGLSILPARDATFSTPS--VRQPDPSAWL-SSGPELTGMPRVRLAAPLAV---LPMEPLP 541
G+++ P+ A +TP V+ P+A + P LT P + AP AV LP+
Sbjct: 584 QGVTLPPSAVAMLNTPDGLVQPATPAAATGEAAPVLTVQPAPQ--APPAVSTPLPLGLQQ 641
Query: 542 PEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTLSLWAPTG 601
P+ +P TP+A++ P QA + +PG E+ PPS PT
Sbjct: 642 PQAQQPPQAPTPQAAA---PPQATTPQPSPGLASSPEK---IVLGQPPSA------TPTA 689
Query: 602 VLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPPELQD 645
+L +++ P Q L E ++ S PP QD
Sbjct: 690 ILTQDSLQMFLP-QERSQQPLSAEGPHLSVPASVIVSAPPPAQD 732
Score = 41.2 bits (95), Expect = 0.003
Identities = 86/353 (24%), Positives = 120/353 (33%), Gaps = 108/353 (30%)
Query: 216 PSPPSP-------GPETPPAGVPPAASSQVWAA------GPAAQEWLSR-----DLLHRP 257
P+P +P GP+ P + PA + Q+ AA GP++ L D H P
Sbjct: 733 PAPATPVAKGAGLGPQAPDSQASPAPAPQIPAAAPLKGPGPSSSPSLPHQAPLGDSPHLP 792
Query: 258 S--------------DALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEA 303
S ++++ P L P + T I V+Q Q G PP
Sbjct: 793 SPHPTRPPSRPPSRPQSVSRPPSEPPLHPCPPPQAPPTLPGIF--VIQNQLGVPPPASNP 850
Query: 304 G--IPGHPTPPATLPSEPVEGVQASPWRPRPVLP-------------THPALTLPVSSD- 347
PG P PP S+P EG P P P LP T L P SD
Sbjct: 851 APTAPGPPQPPLRPQSQPPEG----PLPPAPHLPPSSTSSAVASSSETSSRLPAPTPSDF 906
Query: 348 -------------------------ASSPSPPAPRPERPESLLVSGPSVTLTEGLGTV-R 381
++P PP PR + +V+ P L + + R
Sbjct: 907 QLQFPPSQGPHKSPTPPPTLHLVPEPAAPPPPPPRTFQ----MVTTPFPALPQPKALLER 962
Query: 382 PEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHR 441
Q P S ++L+ + G AAP Q S PL P AA LVS +
Sbjct: 963 FHQVP-----SGIILQNKAGGAPAAP--------QTSTSLGPLTSP-----AASVLVSGQ 1004
Query: 442 SPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDI-----EGPG 489
+P S P GLP + +S+ P+ ++ GPG
Sbjct: 1005 APSGTPTAPSHAPAPAP-MAATGLPPLLPAENKAFASNLPTLNVAKAASSGPG 1056
Score = 34.3 bits (77), Expect = 0.37
Identities = 55/232 (23%), Positives = 82/232 (35%), Gaps = 50/232 (21%)
Query: 204 EPPASTAALRTTPSPPSPGPETPPAGV-------PPAASSQVWAAGPAAQEWLSRDLLHR 256
+PP A L+ PP P P PP G PP A+ + G A H
Sbjct: 1332 QPPPPPATLKVAEPPPRPPPPPPPTGQMNGTVDHPPPAAPERKPLGTAP---------HC 1382
Query: 257 PSDALAKKGL----GPFLQTAKPA--RRGQTSASILPRVVQAQRG-------PQPPPGEA 303
P L K GP PA RG + A + +V +A G + +
Sbjct: 1383 PRLPLRKTYRENVGGPGAPEGTPAGRARGGSPAPLPAKVDEATSGLIRELAAVEDELYQR 1442
Query: 304 GIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPES 363
+ G P PA + +G W + P + D +S S +P+ +
Sbjct: 1443 MLKGPPPEPA---ASAAQGTGDPDWEAPGLPPAKRRKSESPDVDQASFSSDSPQDD---- 1495
Query: 364 LLVSGPSVTLTEGL-----GTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPI 410
TLTE L + +Q P ++P +P S+G A+P P+
Sbjct: 1496 --------TLTEHLQSAIDSILNLQQAPGRTP-APSYPHAASAGTPASPPPL 1538
Score = 29.6 bits (65), Expect = 9.2
Identities = 44/148 (29%), Positives = 55/148 (37%), Gaps = 39/148 (26%)
Query: 205 PPASTAALRTTPSPPSPGPET---------------PPAGVPPAASSQVWAAG----PAA 245
PP T + TTP P P P+ AG PAA + G PAA
Sbjct: 938 PPPRTFQMVTTPFPALPQPKALLERFHQVPSGIILQNKAGGAPAAPQTSTSLGPLTSPAA 997
Query: 246 QEWLSRDL--------LHRPSDA-LAKKGLGPFLQTAKPARRGQTSASILPRV---VQAQ 293
+S H P+ A +A GL P L PA + AS LP + A
Sbjct: 998 SVLVSGQAPSGTPTAPSHAPAPAPMAATGLPPLL----PA-ENKAFASNLPTLNVAKAAS 1052
Query: 294 RGPQPPPG---EAGIPGHPTPPATLPSE 318
GP P G E+ + G PP PS+
Sbjct: 1053 SGPGKPSGLQYESKLSGLKKPPTLQPSK 1080
>gi|110832843 TBP-associated factor 4 [Homo sapiens]
Length = 1085
Score = 62.0 bits (149), Expect = 2e-09
Identities = 107/444 (24%), Positives = 142/444 (31%), Gaps = 100/444 (22%)
Query: 200 GSGTEPPASTAALRTTPSPPSPGPETP-----PAG-VPPAASSQVWAAGPAAQEWLSRDL 253
G+ EPP + A P PGP +P PAG PPAA + G A
Sbjct: 84 GAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRPPPEGSAGS------- 136
Query: 254 LHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPG------ 307
P A A GP A PA+ P + A+ GP P PG PG
Sbjct: 137 -CAPVPAAAAVAAGPEPAPAGPAKPAG------PAALAARAGPGPGPGPGPGPGPGPGKP 189
Query: 308 -------------------HPTPPAT--------------LPSEPVEGVQASPW-----R 329
H PA P+ P +Q P+
Sbjct: 190 AGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVIQTPPFVGAAAP 249
Query: 330 PRPVLPTHPALTLPVS-SDASSPSPPAP--------RPERPESLLVSGPSVTLTEGLGTV 380
P P P+ PA P + + A P PPAP P P + + P + G+
Sbjct: 250 PAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSA 309
Query: 381 RPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSH 440
PA + G P + G AA P G ++ + A P TLAA S
Sbjct: 310 GAAPAPAPAAGGPAGVSGQPGPGAAAAAPAPGVKAESPKRVVQAAPPAAQTLAASGPAST 369
Query: 441 RSPGEPQETCSG-----TEVERPRQTGP-GLPREGARGHMDLSSSEPSQDIEGPGLSILP 494
+ T G V P P GLP+ A S P+ G ++ P
Sbjct: 370 AASMVIGPTMQGALPSPAAVPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATLTP 429
Query: 495 ARDATFSTPSVRQP------------DPSAWL--SSGPELTGMPRVRLA---APLAVLPM 537
T P + QP P L S +L +P+ LA A P
Sbjct: 430 ----TVLAPRLPQPPQNPTNIQNFQLPPGMVLVRSENGQLLMIPQQALAQMQAQAHAQPQ 485
Query: 538 EPLPPEPVRPAALLTPEASSVGGP 561
+ P P P + + S+V P
Sbjct: 486 TTMAPRPATPTSAPPVQISTVQAP 509
Score = 52.8 bits (125), Expect = 1e-06
Identities = 107/429 (24%), Positives = 159/429 (37%), Gaps = 74/429 (17%)
Query: 204 EPPASTAALRTTP-----SPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPS 258
+P A ++T P +PP+P +PPA PAA + P A L+R H
Sbjct: 230 KPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAG 289
Query: 259 DALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSE 318
A + P A + SA P A GP AG+ G P P A +
Sbjct: 290 PPTAAPAVPP-----PAAAQNGGSAGAAPAPAPAAGGP------AGVSGQPGPGAA-AAA 337
Query: 319 PVEGVQASPWRPRPVLPTHP--ALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEG 376
P GV+A P+ V+ P A TL S AS+ + +V GP T+
Sbjct: 338 PAPGVKAE--SPKRVVQAAPPAAQTLAASGPASTAAS-----------MVIGP--TMQGA 382
Query: 377 LGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEE 436
L + P P +PG+P GL G A + A+ RATL
Sbjct: 383 LPS--PAAVPPPAPGTP---TGLPKGAAGAVTQSLSRTPTAT------TSGIRATLTPTV 431
Query: 437 LVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPAR 496
L +P PQ + T ++ Q PG M L SE Q + P ++ +
Sbjct: 432 L----APRLPQPPQNPTNIQN-FQLPPG---------MVLVRSENGQLLMIPQQALAQMQ 477
Query: 497 DATFSTP-SVRQPDPSAWLSSGP------ELTGMPRV-RLAAPLAVLPMEPLPPEPVRPA 548
+ P + P P+ S+ P + G P + R P ++ V+P+
Sbjct: 478 AQAHAQPQTTMAPRPATPTSAPPVQISTVQAPGTPIIARQVTPTTIIKQVSQAQTTVQPS 537
Query: 549 ALLTPEAS-----SVGGPDQARYLESAPGWPVGQEEWGV--AHTSSPPSTQTLSLWAPTG 601
A L +GG Q L +A G + V A T+S +T+T+
Sbjct: 538 ATLQRSPGVQPQLVLGGAAQTASLGTATAVQTGTPQRTVPGATTTSSAATETMENVKKCK 597
Query: 602 VLLPSLVEL 610
L +L++L
Sbjct: 598 NFLSTLIKL 606
>gi|32455273 WNK lysine deficient protein kinase 2 [Homo sapiens]
Length = 2217
Score = 61.2 bits (147), Expect = 3e-09
Identities = 118/466 (25%), Positives = 155/466 (33%), Gaps = 62/466 (13%)
Query: 205 PPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKK 264
PP ST + T P P+P + PP P QV A P +P
Sbjct: 711 PPPSTP-MPTGPGQPAPPGQQPPPLAQPTPLPQVLAPQPVVPL--------QPVPPHLPP 761
Query: 265 GLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGE--------AGIPGHPT-----P 311
L P Q PA+ P AQ PQ PP AGI G P P
Sbjct: 762 YLAPASQVGAPAQLKPLQMPQAPLQPLAQVPPQMPPIPVVPPITPLAGIDGLPPALPDLP 821
Query: 312 PATLPSEP----VEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVS 367
AT+P P P P+ P PAL L P P P R +++ +
Sbjct: 822 TATVPPVPPPQYFSPAVILPSLAAPLPPASPALPLQAVKLPHPPGAPLAMPCR--TIVPN 879
Query: 368 GPSV-----TLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQ 422
P+ G+ + A+ PG P+ AP + P + +
Sbjct: 880 APATIPLLAVAPPGVAALSIHSAVAQLPGQPVYPAAFPQ---MAPTDVPPSPHHTVQNMR 936
Query: 423 PLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPS 482
A P + L + + + PQ T V P+ T P P + + P
Sbjct: 937 --ATPPQPALPPQPTLPPQPVLPPQPTLPPQPVLPPQPTRPPQPVLPPQPML------PP 988
Query: 483 QDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPP 542
Q + P + LP R Q P+A S L G P AP AV +P
Sbjct: 989 QPVLPPQPA-LPVRPEPLQPHLPEQAAPAATPGS-QILLGHP-----APYAVDVAAQVPT 1041
Query: 543 EPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTLSLWAPTGV 602
PV PAA+L+P V P L P +P + S P TQT +L P
Sbjct: 1042 VPVPPAAVLSPPLPEVLLPAAPELL---PQFPSSLATVSASVQSVP--TQTATLLPPANP 1096
Query: 603 LLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPPELQDSVE 648
LP + P Q EP A +PP L S E
Sbjct: 1097 PLPGGPGIASP------CPTVQLTVEPVQEEQASQDKPPGLPQSCE 1136
Score = 43.5 bits (101), Expect = 6e-04
Identities = 88/375 (23%), Positives = 123/375 (32%), Gaps = 36/375 (9%)
Query: 193 ESFFQCVGSGTEPPASTAALRTTPSPP-SPGPETPPAGVPPAASSQVWAAGPAAQEWLSR 251
+S Q V G+ A+ + + SPP S GP P + +P + Q A P
Sbjct: 629 QSSQQSVMLGSLADAAPSPAQCVCSPPVSEGPVLPQS-LPSLGAYQQPTAAPGL------ 681
Query: 252 DLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPP-PGEAGIPGHPT 310
P ++ P LQ P + S P V+ P P PG+ PG
Sbjct: 682 -----PVGSVPAPACPPSLQQHFP----DPAMSFAP-VLPPPSTPMPTGPGQPAPPGQQP 731
Query: 311 PPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPS--PPAPRPERPESLLVSG 368
PP P+ + + P P +P H L +S +P+ P P+ P L
Sbjct: 732 PPLAQPTPLPQVLAPQPVVPLQPVPPHLPPYLAPASQVGAPAQLKPLQMPQAPLQPLAQV 791
Query: 369 PSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDV-AAPEPIMGEPGQASEEFQPLARP 427
P + V P A G P L L + V P P P P
Sbjct: 792 P--PQMPPIPVVPPITPLAGIDGLPPALPDLPTATVPPVPPPQYFSPAVILPSLAAPLPP 849
Query: 428 WRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGL----PREGARGHMDLSSSEPSQ 483
L + + PG P T V T P L P A + P Q
Sbjct: 850 ASPALPLQAVKLPHPPGAPLAMPCRTIVPNAPATIPLLAVAPPGVAALSIHSAVAQLPGQ 909
Query: 484 DIEGPGLSILPARDAT----FSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEP 539
+ + D + ++R P L P L P + P LP +P
Sbjct: 910 PVYPAAFPQMAPTDVPPSPHHTVQNMRATPPQPALPPQPTLPPQP---VLPPQPTLPPQP 966
Query: 540 -LPPEPVRPAALLTP 553
LPP+P RP + P
Sbjct: 967 VLPPQPTRPPQPVLP 981
Score = 41.6 bits (96), Expect = 0.002
Identities = 96/364 (26%), Positives = 140/364 (38%), Gaps = 64/364 (17%)
Query: 201 SGTEPPASTAALRT-TPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSD 259
S E P+ A+ + + + PS P PPA P A SS A P + + P+
Sbjct: 1354 SSKEQPSFLASQQLLSQAGPSNPPGAPPA--PLAPSSPPVTALPQDGAAPATSTMPEPAS 1411
Query: 260 ALAKKGLGPF--------LQTAKP-ARRGQTSASILPRVVQ-AQRGPQPPPG---EAGIP 306
A + GP L+T++P A + ++ P VV A P P +A P
Sbjct: 1412 GTASQAGGPGTPQGLTSELETSQPLAETHEAPLAVQPLVVGLAPCTPAPEAASTRDASAP 1471
Query: 307 GHPTPPATLPSEPVEGV-QASPWRPRPVLPTH-PALTLPVSSDASSPSPPAPRPERPESL 364
P PP P G Q + +P P+LP A++L S S P P P+ P +L
Sbjct: 1472 REPLPPPAPEPSPHSGTPQPALGQPAPLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSAL 1531
Query: 365 LVSG----PSV--------TLTEGLGTVRPEQ---DPAKSPGSPL----------LLRG- 398
G P V +L E L T+ ++ + S G+P+ LRG
Sbjct: 1532 ESDGEGPPPRVGFVDSTIKSLDEKLRTLLYQEHVPTSSASAGTPVEVGDRDFTLEPLRGD 1591
Query: 399 -----LSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGT 453
+ GD+A P P+ P +A L +P + EL R Q T S
Sbjct: 1592 QPRSEVCGGDLALP-PV---PKEAVSGRVQLPQP---LVEKSELAPTRGAVMEQGTSSSM 1644
Query: 454 EVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPA------RDATFSTPSVRQ 507
E ++ G R+G + D S PS + P + PA RD + S +
Sbjct: 1645 TAESSPRSMLGYDRDGRQVASD-SHVVPSVPQDVPAF-VRPARVEPTDRDGGEAGESSAE 1702
Query: 508 PDPS 511
P PS
Sbjct: 1703 PPPS 1706
Score = 38.9 bits (89), Expect = 0.015
Identities = 74/295 (25%), Positives = 101/295 (34%), Gaps = 54/295 (18%)
Query: 205 PPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKK 264
PP A + PG PA P A + V P+ + P AL +
Sbjct: 891 PPGVAALSIHSAVAQLPGQPVYPAAFPQMAPTDV---PPSPHHTVQNMRATPPQPALPPQ 947
Query: 265 GLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPP-PGEAGIPGHPTPPATLPSEPVEGV 323
P Q P + +LP Q R PQP P + +P P LP +P
Sbjct: 948 PTLP-PQPVLPPQPTLPPQPVLPP--QPTRPPQPVLPPQPMLPPQPV----LPPQP---- 996
Query: 324 QASPWRPRPVLPTHPALTLPVSSDASS--------------------PSPPAP--RPERP 361
A P RP P+ P P P ++ S P PPA P P
Sbjct: 997 -ALPVRPEPLQPHLPEQAAPAATPGSQILLGHPAPYAVDVAAQVPTVPVPPAAVLSPPLP 1055
Query: 362 ESLLVSGPSV--TLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASE 419
E LL + P + L TV + + LL A P+ G PG AS
Sbjct: 1056 EVLLPAAPELLPQFPSSLATVSASVQSVPTQTATLL--------PPANPPLPGGPGIASP 1107
Query: 420 EFQPLARPWRATLAAEELVSHRSPGEPQ--ETCSGTEVERPRQTGPGLPREGARG 472
P + + E+ + PG PQ E+ G++V ++ EGA G
Sbjct: 1108 --CPTVQLTVEPVQEEQASQDKPPGLPQSCESYGGSDVTSGKELSDSC--EGAFG 1158
Score = 32.7 bits (73), Expect = 1.1
Identities = 55/214 (25%), Positives = 82/214 (38%), Gaps = 32/214 (14%)
Query: 407 PEPIMGEPGQASEEFQPL-----ARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQT 461
P P+ P +AS++ P ++ + LA+++L+S P P G +
Sbjct: 1332 PLPLSSLPPEASQDSAPYKDQLSSKEQPSFLASQQLLSQAGPSNPP----GAPPAPLAPS 1387
Query: 462 GP---GLPREGAR---GHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLS 515
P LP++GA M +S + GPG + S P + A L+
Sbjct: 1388 SPPVTALPQDGAAPATSTMPEPASGTASQAGGPGTPQGLTSELETSQPLAETHE--APLA 1445
Query: 516 SGPELTGM----PRVRLAAPL-AVLPMEPLPPEPVRPAALLTPEASSVGGPDQARYLESA 570
P + G+ P A+ A P EPLPP PA PE S G Q + A
Sbjct: 1446 VQPLVVGLAPCTPAPEAASTRDASAPREPLPP----PA----PEPSPHSGTPQPALGQPA 1497
Query: 571 PGWP--VGQEEWGVAHTSSPPSTQTLSLWAPTGV 602
P P VG + SPP T+ P+ +
Sbjct: 1498 PLLPAAVGAVSLATSQLPSPPLGPTVPPQPPSAL 1531
Score = 32.0 bits (71), Expect = 1.9
Identities = 36/127 (28%), Positives = 50/127 (39%), Gaps = 13/127 (10%)
Query: 221 PGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLH----RPSDALAKKGLGPFLQTAKPA 276
PG PAG+ A + AA P Q +L R ++ P A + GP Q +P
Sbjct: 17 PGRGAGPAGM---AEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGP--QPPQPL 71
Query: 277 RRGQTSASILPRVV-QAQRGPQPPPGEAGI---PGHPTPPATLPSEPVEGVQASPWRPRP 332
+R R++ + RG P A + PG P PA EPV + P
Sbjct: 72 QRRVLLLCKTRRLIAERARGRPAAPAPAALVAQPGAPGAPADAGPEPVGTQEPGPDPIAA 131
Query: 333 VLPTHPA 339
+ T PA
Sbjct: 132 AVETAPA 138
Score = 32.0 bits (71), Expect = 1.9
Identities = 31/138 (22%), Positives = 46/138 (33%), Gaps = 7/138 (5%)
Query: 378 GTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEEL 437
G P A+ L R + D P + + QPL R L
Sbjct: 25 GMAEPRAKAARPGPQRFLRRSVVESDQEEPPGLEAAEAPGPQPPQPLQRRVLLLCKTRRL 84
Query: 438 VSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARD 497
++ R+ G P V +P PG P + G + + EP D + PA D
Sbjct: 85 IAERARGRPAAPAPAALVAQP--GAPGAPADA--GPEPVGTQEPGPDPIAAAVETAPAPD 140
Query: 498 A---TFSTPSVRQPDPSA 512
+ +VR+ D A
Sbjct: 141 GGPREEAAATVRKEDEGA 158
>gi|7662046 myeloid/lymphoid or mixed-lineage leukemia 4 [Homo
sapiens]
Length = 2715
Score = 60.8 bits (146), Expect = 4e-09
Identities = 114/476 (23%), Positives = 165/476 (34%), Gaps = 97/476 (20%)
Query: 200 GSGTEPPASTAALRTTPSPPSPGPET-PPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPS 258
G EP AA SP P + PP G P + V G + H P
Sbjct: 1787 GPREEPAHLEAAEENQTIVHSPAPSSEPPGGEDPPLDTDVLVPGAPER--------HSPI 1838
Query: 259 DALAKKGLGPFLQTAKPARRGQTSASI-LPRVVQAQR-------GPQPPPGEAGIPGHPT 310
L PA R + A I +P ++R GP P PG H
Sbjct: 1839 QNLDPPLRPDSGSAPPPAPRSFSGARIKVPNYSPSRRPLGGVSFGPLPSPGSPSSLTHHI 1898
Query: 311 PPA---TLPSEPVEGVQASPWRPRPV--------LPTHPALTLPV----------SSDAS 349
P P+ P + SP PRP L T P L +P +S
Sbjct: 1899 PTVGDPDFPAPPRRSRRPSPLAPRPPPSRWASPPLKTSPQLRVPPPTSVVTALTPTSGEL 1958
Query: 350 SPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEP 409
+P PAP P PE L + + GL + + P +++G + +
Sbjct: 1959 APPGPAPSPPPPEDLGPDFEDMEVVSGLSAADLDFAASLLGTEPFQEEIVAAGAMGSSH- 2017
Query: 410 IMGEPGQAS-EEFQPLARPWR---ATLAAEELVSHRSPGEPQ-ETCSGTE---------V 455
G PG +S EE P +R ++A L +PG P+ E G + V
Sbjct: 2018 --GGPGDSSEEESSPTSRYIHFPVTVVSAPGLAPSATPGAPRIEQLDGVDDGTDSEAEAV 2075
Query: 456 ERPR-----QTGPGLPREGARGHMDLSSSEPS-----------QDIEGPGLSILPARDAT 499
++PR +GPG+ R G G + P +++ GPG R+ +
Sbjct: 2076 QQPRGQGTPPSGPGVVRAGVLGAAGDRARPPEDLPSEIVDFVLKNLGGPGDGGAGPREES 2135
Query: 500 F--STPSVRQPDPSAWLSSGPE--------LTGMPRVRLAAPLAVLPMEPLPPEPVRPAA 549
+ P PS L++ P L G P VR+ + L P PP+P
Sbjct: 2136 LPPAPPLANGSQPSQGLTASPADPTRTFAWLPGAPGVRVLS----LGPAPEPPKPATSKI 2191
Query: 550 LLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTLSLWAPTGVLLP 605
+L + V +++ A G+ E PP T+S APT LP
Sbjct: 2192 ILVNKLGQV-------FVKMA-----GEGEPVPPPVKQPPLPPTISPTAPTSWTLP 2235
Score = 42.0 bits (97), Expect = 0.002
Identities = 95/373 (25%), Positives = 123/373 (32%), Gaps = 86/373 (23%)
Query: 207 ASTAALRTTP---SPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAK 263
A A R P SPP+P P T G PP S V P
Sbjct: 480 AEREAARAGPEGTSPPTPTPSTATGG-PPEDSPTV-----------------APKSTTFL 521
Query: 264 KGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGV 323
K + F+ AR + + PR + P+PP E P P T P P E
Sbjct: 522 KNIRQFIMPVVSARSSRVIKT--PRRFMDEDPPKPPKVEVSPVLRP-PITTSPPVPQE-- 576
Query: 324 QASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPS---VTLTEGLGTV 380
P PV P+ P P PS P P PE+ S+L P+ +LT L
Sbjct: 577 ------PAPV-PSPPRAPTP-------PSTPVPLPEKRRSIL-REPTFRWTSLTRELPPP 621
Query: 381 RPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSH 440
P P +P P P A+ +PL L A +
Sbjct: 622 PPAPPPPPAPSPP--------------------PAPATSSRRPL------LLRAPQF--- 652
Query: 441 RSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATF 500
+P E + + P P P E D S +EP G + R A
Sbjct: 653 -TPSEAHLKIYESVLTPPPLGAPEAP-EPEPPPADDSPAEPEPRAVGRTNHLSLPRFAPV 710
Query: 501 STPSVR---QPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEASS 557
T V+ P + LS+GP+ + +L PL L + LP P L P S
Sbjct: 711 VTTPVKAEVSPHGAPALSNGPQ----TQAQLLQPLQALQTQLLPQALPPPQPQLQPPPS- 765
Query: 558 VGGPDQARYLESA 570
P Q LE A
Sbjct: 766 ---PQQMPPLEKA 775
Score = 40.4 bits (93), Expect = 0.005
Identities = 72/292 (24%), Positives = 91/292 (31%), Gaps = 56/292 (19%)
Query: 288 RVVQAQRGPQPPPGEAGIPGHP-TPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSS 346
R V + P EA +P P TPPA P P+ SP P P+ P P P S
Sbjct: 384 RAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSP--PPPLCPPPP----PPVS 437
Query: 347 DASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAA 406
PSPP P P + E P V T RP P++ G
Sbjct: 438 PPPLPSPPPP-PAQEEQEESPPPVVPATCSRKRGRPPLTPSQRAEREAARAGPEGTSPPT 496
Query: 407 PEPIMGEPGQASEEFQPLARPWRATLAAE------ELVSHRS--------------PGEP 446
P P G + P P T +VS RS P +P
Sbjct: 497 PTPSTATGGPPEDS--PTVAPKSTTFLKNIRQFIMPVVSARSSRVIKTPRRFMDEDPPKP 554
Query: 447 QETCSGTEVERPRQTGPGLPREGAR-GHMDLSSSEPSQDIEGPGLSILPARDATFSTPSV 505
+ + P T P +P+E A + + PS + P R+ TF
Sbjct: 555 PKVEVSPVLRPPITTSPPVPQEPAPVPSPPRAPTPPSTPVPLPEKRRSILREPTFR---- 610
Query: 506 RQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEASS 557
W S EL P P PP P P+ P SS
Sbjct: 611 -------WTSLTRELP--------------PPPPAPPPPPAPSPPPAPATSS 641
Score = 37.7 bits (86), Expect = 0.034
Identities = 87/367 (23%), Positives = 129/367 (35%), Gaps = 79/367 (21%)
Query: 204 EPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAK 263
EP +L PP P P PPA PP A A + + L R PS+A K
Sbjct: 606 EPTFRWTSLTRELPPPPPAPPPPPAPSPPPA-----PATSSRRPLLLRAPQFTPSEAHLK 660
Query: 264 KGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGV 323
+ P G A P+PPP + P P P A + +
Sbjct: 661 ----IYESVLTPPPLGAPEAP----------EPEPPPADDS-PAEPEPRAVGRTNHLS-- 703
Query: 324 QASPWRPRPVLPTH-PALTLPVSSDASSPSPPA--PRPERPESLLVSGPSV---TLTEGL 377
LP P +T PV ++ S PA P+ LL ++ L + L
Sbjct: 704 ----------LPRFAPVVTTPVKAEVSPHGAPALSNGPQTQAQLLQPLQALQTQLLPQAL 753
Query: 378 GTVRPEQDPAKSPGS-PLLLRGLSSGDVAAP-----EPIMGEPGQASEEFQPLARPWRAT 431
+P+ P SP P L + +G + P E + +A + + + +
Sbjct: 754 PPPQPQLQPPPSPQQMPPLEKARIAGVGSLPLSGVEEKMFSLLKRAKVQLFKIDQQQQQK 813
Query: 432 LAA----------EEL------VSHRSPGEPQETCSGTEVERPRQTGPGLPREGAR---- 471
+AA EE+ +S R P ++ E +R R +GP P +G R
Sbjct: 814 VAASMPLSPGGQMEEVAGAVKQISDRGPVRSED--ESVEAKRERPSGPESPVQGPRIKHV 871
Query: 472 ---GHMDLSSSEPSQDIEGPGLSILPARD----ATFSTPSVRQPDPSAWLSSGPELTGMP 524
+ L + + P LS LP RD AT T S + + S P +
Sbjct: 872 CRHAAVALGQARAMVPEDVPRLSALPLRDRQDLATEDTSSASETE------SVPSRSRRG 925
Query: 525 RVRLAAP 531
+V A P
Sbjct: 926 KVEAAGP 932
Score = 37.7 bits (86), Expect = 0.034
Identities = 79/303 (26%), Positives = 103/303 (33%), Gaps = 79/303 (26%)
Query: 216 PSPPSPGPETPPAGVP--PAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTA 273
P+PP P G+ PA ++ +A P A + LGP +
Sbjct: 2138 PAPPLANGSQPSQGLTASPADPTRTFAWLPGAP-------------GVRVLSLGPAPEPP 2184
Query: 274 KPARRGQTSASILPRVVQAQRG---PQPPPGEAGIPGHPTPPA---------TLPSEPVE 321
KPA + L +V G P PPP + P PP TLP P+
Sbjct: 2185 KPATSKIILVNKLGQVFVKMAGEGEPVPPP----VKQPPLPPTISPTAPTSWTLPPGPLL 2240
Query: 322 GVQ--ASPWRPRPVLPTHPALTLPVSSDASSP----------------SPPAPRPERPES 363
GV RP P P P LTL +SS +SP SPPAP P +
Sbjct: 2241 GVLPVVGVVRPAPP-PPPPPLTLVLSSGPASPPRQAIRVKRVSTFSGRSPPAPPPYKAPR 2299
Query: 364 LLVSGPSVTLT---EGLG------------TVRPEQDPAKSPGSPLLLRGLSSGDVAAPE 408
L G + T GLG TVR D PG P S G +
Sbjct: 2300 LDEDGEASEDTPQVPGLGSGGFSRVRMKTPTVRGVLD-LDRPGEP--AGEESPGPLQERS 2356
Query: 409 PIMGEPGQASEEFQP------LARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTG 462
P++ P + L W + E S P P + E + P++TG
Sbjct: 2357 PLLPLPEDGPPQVPDGPPDLLLESQWH-HYSGEASSSEEEPPSPDD----KENQAPKRTG 2411
Query: 463 PGL 465
P L
Sbjct: 2412 PHL 2414
Score = 29.6 bits (65), Expect = 9.2
Identities = 66/287 (22%), Positives = 95/287 (33%), Gaps = 46/287 (16%)
Query: 303 AGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPE 362
A P P A PS P + S RP P P P + + + P+PE P
Sbjct: 200 AQAPQAPRSRACEPSTP----RRSRGRP-PGRPAGPCRRKQQAVVVAEAAVTIPKPEPPP 254
Query: 363 SLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQ 422
P V + G+ + ++ P PG+P RG S G G +
Sbjct: 255 ------PVVPVKHQTGSWKCKEGPGPGPGTPR--RGGQSSRGGRGGRGRGRGGGLPFVIK 306
Query: 423 PLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGL--------PREGARGHM 474
++R + + L G+ Q S +V + R+ G G +
Sbjct: 307 FVSRAKKVKMGQLSLGLESGQGQGQHEESWQDVPQ-RRVGSGQGGSPCWKKQEQKLDDEE 365
Query: 475 DLSSSEPSQDIEGP-------GLSILPA---RDATFSTPSVRQPDPSAWLSSGPELTGMP 524
+ E +D EG ++PA +A P + P PS P T P
Sbjct: 366 EEKKEEEEKDKEGEEKEERAVAEEMMPAAEKEEAKLPPPPLTPPAPSPPPPLPPPSTSPP 425
Query: 525 RVRLAAPLAVLPMEPLPPEPVRPAALLTPEASSVGGPDQARYLESAP 571
P+ P PP PV P L +P P Q ES P
Sbjct: 426 P----------PLCPPPPPPVSPPPLPSPPPP----PAQEEQEESPP 458
>gi|116284392 mucin 2 precursor [Homo sapiens]
Length = 5179
Score = 59.3 bits (142), Expect = 1e-08
Identities = 85/393 (21%), Positives = 120/393 (30%), Gaps = 57/393 (14%)
Query: 205 PPASTAAL--RTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALA 262
PP ST L TTPSPP+ TPP P+ P PS ++
Sbjct: 1409 PPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPPTTT---------PSPPIS 1459
Query: 263 KKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEG 322
P T P + + P PP P+PP T P P
Sbjct: 1460 TTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTT------PSPPTTTPITPPAS 1513
Query: 323 VQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRP 382
P P PT T P ++ +PSPP P P + + P T T
Sbjct: 1514 TTTLPPTTTPSPPTTTTTTPPPTT---TPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT 1570
Query: 383 EQDPAKSPG-------SPLLLRGLSSGDVAAPEP---IMGEPGQASEEFQPLARPWRATL 432
P +P SP + + P P P + P P
Sbjct: 1571 TPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPT 1630
Query: 433 AAEELVSHRSPGEPQETCS----GTEVERPRQTGPG---------LPREGARGHMDLSSS 479
+ L +P P T + T P T P P + + S
Sbjct: 1631 STTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPS 1690
Query: 480 EPSQDIEGPGLSILPARD-ATFSTPS---VRQPDPSAWLSSGP---------ELTGMPRV 526
P+ + P + P+ T +TPS P P+ + P +T +P
Sbjct: 1691 PPTTTMTTPSPTTTPSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPT 1750
Query: 527 RLAAPLAVLPMEP-LPPEPVRPAALLTPEASSV 558
++PL P+ P + P P + TP V
Sbjct: 1751 TTSSPLTTTPLPPSITPPTFSPFSTTTPTTPCV 1783
Score = 53.1 bits (126), Expect = 8e-07
Identities = 75/335 (22%), Positives = 97/335 (28%), Gaps = 41/335 (12%)
Query: 203 TEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALA 262
T P T T P +P P T PPA+++ + P PS
Sbjct: 1482 TTPSPPTTTTTTPPPTTTPSPPTTTPITPPASTTTL---PPTT----------TPSPPTT 1528
Query: 263 KKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEG 322
P T P + + P PPP P PP T PS P
Sbjct: 1529 TTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTTTP----PPTTTPSPPTTT 1584
Query: 323 VQASP-----WRPRPVLPTHPALTLPVSSDASSPSPPAPRP--------ERPESLLVSGP 369
+ P P P+ P T ++PSPP P P + S P
Sbjct: 1585 TPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP 1644
Query: 370 SVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEF---QPLAR 426
T T T P +P P+ PI P + P
Sbjct: 1645 PTTTTTPPPTTTPSPPTTTTPSPPITTTTTPPPTTTPSSPITTTPSPPTTTMTTPSPTTT 1704
Query: 427 PWRATLAAEELVSHRSPGEPQETCS----GTEVERPRQTGPGLPREGARGHMDLSSSEPS 482
P S +P P T + T P T LP + + PS
Sbjct: 1705 PSSPITTTTTPSSTTTPSPPPTTMTTPSPTTTPSPPTTTMTTLPPTTTSSPLTTTPLPPS 1764
Query: 483 QDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSG 517
I P S P T +TP V + + WL SG
Sbjct: 1765 --ITPPTFS--PFSTTTPTTPCVPLCNWTGWLDSG 1795
Score = 47.4 bits (111), Expect = 4e-05
Identities = 67/291 (23%), Positives = 90/291 (30%), Gaps = 27/291 (9%)
Query: 309 PTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSG 368
P+PP T PS P P P PT T P ++ +PSPP P
Sbjct: 1399 PSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTT---TPSPPITTTTTPPPTTTPS 1455
Query: 369 PSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPW 428
P ++ T T P P +P P + + P P + P P
Sbjct: 1456 PPISTT----TTPP---PTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPI 1508
Query: 429 RATLAAEELVSHRSPGEPQETCS---GTEVERPRQTGPGLPREGARGHMDLSSSEPSQDI 485
+ L +P P T + T P T P P ++ P
Sbjct: 1509 TPPASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPP--- 1565
Query: 486 EGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPV 545
P + P T S P+ P P ++ P T P + P P P
Sbjct: 1566 --PTTTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTP----SPPTTTTTTPPPTTTPS 1619
Query: 546 RPAAL-LTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTLS 595
P +TP S+ P S P P T SPP+T T S
Sbjct: 1620 PPTTTPITPPTSTTTLPPTT--TPSPP--PTTTTTPPPTTTPSPPTTTTPS 1666
Score = 39.7 bits (91), Expect = 0.009
Identities = 66/317 (20%), Positives = 93/317 (29%), Gaps = 32/317 (10%)
Query: 296 PQPPPGEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPA 355
P PPP PP T PS P P P+ P T ++PSPP
Sbjct: 1406 PSPPPTSTTT----LPPTTTPSPPTTTTTTPP---PTTTPSPPITTTTTPPPTTTPSPPI 1458
Query: 356 PRPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPG 415
P P T T T P SP + + + P P
Sbjct: 1459 STTTTPPPTTTPSPPTT-TPSPPTTTP------SPPTTTTTTPPPTTTPSPPTTTPITPP 1511
Query: 416 QASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMD 475
++ P P T +P P + T + P T P
Sbjct: 1512 ASTTTLPPTTTPSPPTTTTTTPPPTTTPSPP----TTTPITPPTSTTTLPPTTTPSPPPT 1567
Query: 476 LSSSEPSQDIEGPGLSILPARD--ATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPL- 532
+++ P P + P+ T + P P P ++ P T P P+
Sbjct: 1568 TTTTPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPIT 1627
Query: 533 -----AVLPMEPLPPEP----VRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVA 583
LP P P P TP + P + P P +
Sbjct: 1628 PPTSTTTLPPTTTPSPPPTTTTTPPPTTTPSPPTTTTPSPPITTTTTPP-PTTTPSSPIT 1686
Query: 584 HTSSPPSTQTLSLWAPT 600
T SPP+T T++ +PT
Sbjct: 1687 TTPSPPTT-TMTTPSPT 1702
Score = 34.7 bits (78), Expect = 0.29
Identities = 43/182 (23%), Positives = 63/182 (34%), Gaps = 29/182 (15%)
Query: 201 SGTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDA 260
+GT+ P +T TT P+P P G P S+ P A+ S +
Sbjct: 4168 TGTQTPTTTPITTTTTVTPTPTPTGTQTGPPTHTST-----APIAELTTSNPPPESSTPQ 4222
Query: 261 LAKKGLGPFLQTAKPARRGQTSASILPRVVQ--AQRGPQPPPGEAGIPGHPT---PPATL 315
++ T+ P T S LP ++ + P P G T PP+T
Sbjct: 4223 TSR-------STSSPLTESTTLLSTLPPAIEMTSTAPPSTPTAPTTTSGGHTLSPPPSTT 4275
Query: 316 PSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTE 375
S P +P R + V + +S P P P +S PS+ T
Sbjct: 4276 TSPP-----GTPTRGTTTGSSSAPTPSTVQTTTTSAWTPTPTP-------LSTPSIIRTT 4323
Query: 376 GL 377
GL
Sbjct: 4324 GL 4325
Score = 31.2 bits (69), Expect = 3.2
Identities = 50/260 (19%), Positives = 70/260 (26%), Gaps = 11/260 (4%)
Query: 343 PVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSG 402
P+ ++PSPP P P + + P T T P +P P+
Sbjct: 1391 PMDKCITTPSPPTTTPSPPPTSTTTLPPTTTPSPPTTTTTTPPPTTTPSPPITTTTTPPP 1450
Query: 403 DVAAPEPI--MGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCS---GTEVER 457
PI P + P P T + + P T S T +
Sbjct: 1451 TTTPSPPISTTTTPPPTTTPSPPTTTPSPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP 1510
Query: 458 PRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLS--ILPARDATFSTPSVRQPDPSAWLS 515
P T P +++ P P + I P T P+ P +
Sbjct: 1511 PASTTTLPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITPPTSTTTLPPTTTPSPPPTTTT 1570
Query: 516 SGPELT--GMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEASSVGGPDQARYLESAPGW 573
+ P T P +P + P P P T P P
Sbjct: 1571 TPPPTTTPSPPTTTTPSPPTITTTTPPPTTTPSPPTTTTTTPPPTTTPSPPTTTPITP-- 1628
Query: 574 PVGQEEWGVAHTSSPPSTQT 593
P T SPP T T
Sbjct: 1629 PTSTTTLPPTTTPSPPPTTT 1648
>gi|154146199 sal-like 3 [Homo sapiens]
Length = 1300
Score = 59.3 bits (142), Expect = 1e-08
Identities = 85/368 (23%), Positives = 131/368 (35%), Gaps = 47/368 (12%)
Query: 226 PPAGVP----PAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQT 281
PP G P P ++ +GP ++ ++ +K F + A ++
Sbjct: 20 PPDGAPEHAAPGEGAEDADSGPESRSG-------GEETSVCEKCCAEFFKWADFLEHQRS 72
Query: 282 SASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVE-------GVQASPWRPRPVL 334
+ P ++ + P PPP + P PA+ PSE E G + + RPV
Sbjct: 73 CTKLPPVLIVHEDAPAPPPEDFPEPS----PASSPSERAESEAAEEAGAEGAEGEARPVE 128
Query: 335 PTHPALTLPVSSDASSPSPPAPRPERPESLL-VSGPSVTLTEGLGT---VRPEQDPAKSP 390
+ + D +P PP P P +VTL L T V A++
Sbjct: 129 KEAEPMDAEPAGDTRAPRPPPAAPAPPTPAYGAPSTNVTLEALLSTKVAVAQFSQGARAA 188
Query: 391 GSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETC 450
G G G AA P++ E A ++ Q + ++ + R P P
Sbjct: 189 GG----SGAGGGVAAAAVPLILEQLMALQQQQIHQLQLIEQIRSQVALMQRPPPRP---- 240
Query: 451 SGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATF-STPSVRQPD 509
S + P GP + + LS+ P+ I G G PA A F + +P+
Sbjct: 241 SLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSG----PAAPAAFEGAQPLSRPE 296
Query: 510 PSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPV---RPAALLTPEASSVGGPDQARY 566
A GP P AAP P P+ +P + TP A + G
Sbjct: 297 SGASTPGGPAEPSAPAAPSAAPAPAAPAPAPAPQSAASSQPQSASTPPALAPGS-----L 351
Query: 567 LESAPGWP 574
L +APG P
Sbjct: 352 LGAAPGLP 359
Score = 39.7 bits (91), Expect = 0.009
Identities = 42/162 (25%), Positives = 52/162 (32%), Gaps = 30/162 (18%)
Query: 205 PPASTAALRTTPSPPSPGPETPP--------AGVPPAASSQVWAAGPAAQEWLSRDLLHR 256
PP + + PS P P P P AG P AA + A PAA E L R
Sbjct: 237 PPRPSLSPAAAPSAPGPAPSQLPGLAALPLSAGAPAAAIAGSGPAAPAAFE--GAQPLSR 294
Query: 257 PSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLP 316
P + G GP + SA P A P P P P +
Sbjct: 295 PESGASTPG-GP----------AEPSAPAAPSAAPAPAAPAPAPA---------PQSAAS 334
Query: 317 SEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRP 358
S+P P +L P L P+ S+ P P
Sbjct: 335 SQPQSASTPPALAPGSLLGAAPGLPSPLLPQTSASGVIFPNP 376
>gi|116256464 hypothetical protein LOC343990 [Homo sapiens]
Length = 962
Score = 58.9 bits (141), Expect = 1e-08
Identities = 115/455 (25%), Positives = 157/455 (34%), Gaps = 89/455 (19%)
Query: 206 PASTAALRTTP-----SPPSPGP-------ETPPAGVPPAASSQVWAAGPAAQEWLSRDL 253
P S LR P PP+PGP E PPAG A+ + A ++ S
Sbjct: 344 PESAPTLRVEPPSPPEGPPNPGPDGGKQDGEAPPAGPCAPATDKAEEVVCAPEDVASPFP 403
Query: 254 LHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGH-PTPP 312
P P + P+ R S+ P+ + P P E G PG P P
Sbjct: 404 TAIPEGDTTPPETDPAATSEAPSARDGPERSV-PKEAEPTP-PVLPDEEKGPPGPAPEPE 461
Query: 313 ATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPR---PERPESL----- 364
+EP G P R + T P S A +PSPPAP+ RP +
Sbjct: 462 REAETEPERGAGTEPER----IGTEP-------STAPAPSPPAPKSCLKHRPAAASEGPA 510
Query: 365 ------------LVSGPSVTLTEGLGTVRPEQDPAKSPGS--------------PLLLRG 398
+ GP E RP+ + A++P + LRG
Sbjct: 511 ASPPLAAAESPPVEPGPGSLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRG 570
Query: 399 LSSGDV----AAPEPIMGEPGQASEEFQPLARP---WRATLAAEEL-----VSHRSPGEP 446
V A P P + P + + PLAR WR+ A ++L H PG
Sbjct: 571 AKKFSVSSCRARPRPGVSRPLERASGRLPLARSGPVWRSEAALDDLQGLPEPQHAKPGPR 630
Query: 447 QETCSGTEVERPRQTGPGLPREGAR-GHMDLSSSEPSQDIEGPGLSILPARDATFSTPSV 505
+ G + R P PR+ + + EP + P P+ D +
Sbjct: 631 KLAERGPQDSGDRAASPAGPRKSPQEAAAAPGTREPCPAAQEPA----PSEDRNPFPVKL 686
Query: 506 RQPDPSAWLSSG--PELTGMPR----VRLAAPLAVLPMEPLPPEPVRPAALLTPEASSVG 559
R S G E+ G+ R VRL L VLP E P P AL A S
Sbjct: 687 RSTSLSLKYRDGASQEVKGVKRYSAEVRLERSLTVLPKEEKCPLGTAP-ALRGTRAPSDQ 745
Query: 560 GPDQAR---YLESAPGWPVGQ--EEWGVAHTSSPP 589
G +AR L S P P + + + H +PP
Sbjct: 746 GKGKARPPEPLSSKPPLPRKPLLQSFTLPHQPAPP 780
Score = 37.7 bits (86), Expect = 0.034
Identities = 88/362 (24%), Positives = 121/362 (33%), Gaps = 69/362 (19%)
Query: 200 GSGTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSD 259
G+GTEP T P+P P P++ P AAS A+ P A +
Sbjct: 471 GAGTEPERIGTEPSTAPAPSPPAPKSCLKHRPAAASEGPAASPPLAA--AESPPVEPGPG 528
Query: 260 ALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGE-----AGIPGHPTPPAT 314
+L + P A+ A A +A+RG G + P P +
Sbjct: 529 SLDAEAAAPERPKAERAEAPPAGAERAAPERKAERGGAELRGAKKFSVSSCRARPRPGVS 588
Query: 315 LPSEPVEG----VQASP-WRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGP 369
P E G ++ P WR L L P P +P P L GP
Sbjct: 589 RPLERASGRLPLARSGPVWRSEAALDDLQGL----------PEPQHAKP-GPRKLAERGP 637
Query: 370 SVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPL--ARP 427
+ D A SP P S AA P EP A++E P P
Sbjct: 638 -----------QDSGDRAASPAGP-----RKSPQEAAAAPGTREPCPAAQEPAPSEDRNP 681
Query: 428 WRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEG 487
+ L + L G QE G+ R A ++ S + ++ +
Sbjct: 682 FPVKLRSTSLSLKYRDGASQEV-------------KGVKRYSAEVRLERSLTVLPKEEKC 728
Query: 488 PGLSILPARDATFSTPS------VRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLP 541
P L PA T PS R P+P LSS P L P ++ LP +P P
Sbjct: 729 P-LGTAPALRGT-RAPSDQGKGKARPPEP---LSSKPPLPRKPLLQ----SFTLPHQPAP 779
Query: 542 PE 543
P+
Sbjct: 780 PD 781
>gi|41281612 zinc finger protein 828 [Homo sapiens]
Length = 812
Score = 58.5 bits (140), Expect = 2e-08
Identities = 100/444 (22%), Positives = 154/444 (34%), Gaps = 82/444 (18%)
Query: 216 PSPPSP-GPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAK 274
P+P +P P+ P + V P + + + P+ +S + + L P
Sbjct: 148 PTPLTPLEPQKPGSVVSPELQTPLPSPEPSKPASVSSPEPPKSVPVCESQKLAPV----- 202
Query: 275 PARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPP-ATLPSEPVEGVQASPWRPRPV 333
P+ Q A + P V+A P ++ P PP A+ P PV PW P P
Sbjct: 203 PSPEPQKPAPVSPESVKATLSNPKPQKQSHFPETLGPPSASSPESPVLAASPEPWGPSPA 262
Query: 334 L-PTHPALTLPVSSDASSPSP-PAPRPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPG 391
P S + PSP +P P +P + P RP PA SPG
Sbjct: 263 ASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPR----------RPA--PAVSPG 310
Query: 392 SPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCS 451
S G +P P P +S PW+ P +P + S
Sbjct: 311 S------WKPGPPGSPRPWKSNPSASS-------GPWK-------------PAKPAPSVS 344
Query: 452 GTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQP--D 509
GP P + S P P +S + ++ S S + P
Sbjct: 345 ---------PGPWKP---------IPSVSPGPWKPTPSVSSASWKSSSVSPSSWKSPPAS 386
Query: 510 PSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEASSVGGPDQARYLES 569
P +W S PEL +P + P+ PE +P L+PE S G + R
Sbjct: 387 PESWKSGPPEL--RKTAPTLSPEHWKAVPPVSPELRKPGPPLSPEIRSPAGSPELRKPSG 444
Query: 570 APG-WPVGQEEWGVAHTSSP-PSTQTLS------LWAPTGVLLPS---LVELEYPFQAGR 618
+P W + ++ + S P +Q S LW + + P E P +G
Sbjct: 445 SPDLWKLSPDQRKTSPASLDFPESQKSSRGGSPDLWKSSFFIEPQKPVFPETRKPGPSGP 504
Query: 619 GAS--LQQELTEPTLALSAESHRP 640
S ++ +P L++ E +P
Sbjct: 505 SESPKAASDIWKPVLSIDTEPRKP 528
Score = 57.0 bits (136), Expect = 5e-08
Identities = 97/370 (26%), Positives = 130/370 (35%), Gaps = 69/370 (18%)
Query: 201 SGTEPPASTAALRTTPSPPSPGPE-TPPAGVPPAASSQVWAAGPAAQEWL---------S 250
S EPP S + P P PE PA V P S + + P Q+ S
Sbjct: 183 SSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSP-ESVKATLSNPKPQKQSHFPETLGPPS 241
Query: 251 RDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQP------------ 298
P A + + GP + +R+ + S PR P+P
Sbjct: 242 ASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSPSESPEPWKPFPAVSPEPR 301
Query: 299 ------PPG--EAGIPGHPTPPATLPS---------EPVEGVQASPWRPRPVLPTHPALT 341
PG + G PG P P + PS +P V PW+P P + P
Sbjct: 302 RPAPAVSPGSWKPGPPGSPRPWKSNPSASSGPWKPAKPAPSVSPGPWKPIPSVSPGPWKP 361
Query: 342 LPVSSDAS------SPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLL 395
P S AS SPS P PES SGP L + T+ PE A P SP L
Sbjct: 362 TPSVSSASWKSSSVSPSSWKSPPASPES-WKSGPP-ELRKTAPTLSPEHWKAVPPVSPEL 419
Query: 396 LRGLSSGDVAAPEPIMGEPGQASEEFQPLARP--WR----------ATLAAEELVSHRSP 443
+ G +PE + P + E +P P W+ A+L E
Sbjct: 420 RK---PGPPLSPE--IRSPAGSPELRKPSGSPDLWKLSPDQRKTSPASLDFPESQKSSRG 474
Query: 444 GEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSI--LPARDATFS 501
G P S +E + P + G G + S + + DI P LSI P + A F
Sbjct: 475 GSPDLWKSSFFIEPQKPVFPETRKPGPSGPSE--SPKAASDIWKPVLSIDTEPRKPALFP 532
Query: 502 TPSVRQPDPS 511
P+ P S
Sbjct: 533 EPAKTAPPAS 542
Score = 49.7 bits (117), Expect = 9e-06
Identities = 79/326 (24%), Positives = 122/326 (37%), Gaps = 60/326 (18%)
Query: 338 PALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLR 397
PAL++ S SP +P+P L P ++ L T P +P+K P S
Sbjct: 128 PALSMETQKLGSVLSPESPKPTPLTPLEPQKPGSVVSPELQTPLPSPEPSK-PAS----- 181
Query: 398 GLSSGDVAAPEPIMGEPGQASEEFQPLARP---WRATLAAEELVSHRSPGEPQETCSGTE 454
V++PEP P S++ P+ P A ++ E + + S +PQ+ +
Sbjct: 182 ------VSSPEPPKSVPVCESQKLAPVPSPEPQKPAPVSPESVKATLSNPKPQK-----Q 230
Query: 455 VERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWL 514
P G P + + ++ P P S + A ++P R+P P
Sbjct: 231 SHFPETLG---PPSASSPESPVLAASPEPWGPSPAASPESRKSARTTSPEPRKPSP---- 283
Query: 515 SSGPELTGMPRVRLAAPLAVLPMEPLP---PEPVRPAALLTPEASSVGGPDQARYLESAP 571
S PE P +P P PEP RPA ++P + G P R +S P
Sbjct: 284 SESPE----------------PWKPFPAVSPEPRRPAPAVSPGSWKPGPPGSPRPWKSNP 327
Query: 572 GWPVGQEEWGVAHTSSPPSTQTLSLWAPTGVLLPSLVELEYPFQAGRGASLQQELTEPTL 631
G W A P + + W P + P + P + AS + P+
Sbjct: 328 SASSG--PWKPA---KPAPSVSPGPWKPIPSVSPGPWK---PTPSVSSASWKSSSVSPSS 379
Query: 632 ----ALSAESHR--PPELQDSVEGLS 651
S ES + PPEL+ + LS
Sbjct: 380 WKSPPASPESWKSGPPELRKTAPTLS 405
>gi|122937496 WAS/WASL interacting protein family, member 3 [Homo
sapiens]
Length = 483
Score = 58.5 bits (140), Expect = 2e-08
Identities = 71/285 (24%), Positives = 99/285 (34%), Gaps = 33/285 (11%)
Query: 216 PSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKP 275
P PP P P TPP +PPA+ A P LH P + P L P
Sbjct: 224 PPPPPPPPPTPPP-LPPASVLSDKAVKPQLAP------LHLPP-------IPPPLPLLPP 269
Query: 276 ARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPT--PPATLPSEPVEGVQASPWRPRPV 333
A AQ P PPP +P + + P A+LP+ P+ GV +S P P+
Sbjct: 270 CGYPGLKAEPASPAQDAQEPPAPPPP---LPPYASCSPRASLPAPPLPGVNSSSETPPPL 326
Query: 334 LPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVR-PEQDPAKSPGS 392
P P+ P + P P P + L G G + P PA+SP +
Sbjct: 327 PPKSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTT 386
Query: 393 PLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGE--PQETC 450
L S A P GQ + + + + P E P +
Sbjct: 387 EL---SSKSQQATAWTPTQQPGGQLRNGSLHIIDDFESKFTFHSVEDFPPPDEYKPCQKI 443
Query: 451 SGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPA 495
+++ R R GP L E + S DI+G + A
Sbjct: 444 YPSKIPRSRTPGPWLQAEAV--------GQSSDDIKGRNSQVTQA 480
Score = 43.1 bits (100), Expect = 8e-04
Identities = 45/165 (27%), Positives = 57/165 (34%), Gaps = 39/165 (23%)
Query: 207 ASTAALR-TTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKG 265
A TA R P+PP P P PP +PP PS + K
Sbjct: 162 ARTAPPRPNVPAPPPPTPPPPPPPLPPPL----------------------PSSSPIKT- 198
Query: 266 LGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQA 325
P + P +G + P V A P PPP P PPA++ S+ Q
Sbjct: 199 --PLVSPPGPLTKGNLPV-VAPPVPCAPPPPPPPPPPTP---PPLPPASVLSDKAVKPQL 252
Query: 326 SPWRPRPVLPTHPAL---------TLPVSSDASSPSPPAPRPERP 361
+P P+ P P L P S + PPAP P P
Sbjct: 253 APLHLPPIPPPLPLLPPCGYPGLKAEPASPAQDAQEPPAPPPPLP 297
Score = 42.4 bits (98), Expect = 0.001
Identities = 98/433 (22%), Positives = 140/433 (32%), Gaps = 85/433 (19%)
Query: 216 PSPPSPGPETPPAGVPP----------AASSQVWAAGPAAQEWLSRDLLHRPSDALAK-- 263
P PP P PP G PP +S + A P + L D+ + L K
Sbjct: 6 PPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADI--QQGTRLRKVT 63
Query: 264 ---KGLGPFLQTAKPARR------GQTSASILPRVVQAQRGPQP---PPGEAGI------ 305
P ++++K + AS P + G P P G+ +
Sbjct: 64 QINDRSAPQIESSKGTNKEGGGSANTRGASTPPTLGDLFAGGFPVLRPAGQRDVAGGKTG 123
Query: 306 --PGHPTPPATLPSEPVEGVQASPWRPR--PVLPTH-PALTLPVSSDASSPSPPAPRPER 360
PG P LP++ + G P PR H A T P + +P PP P P
Sbjct: 124 QGPGSRAPSPRLPNKTISGPLIPPASPRLGNTSEAHGAARTAPPRPNVPAPPPPTPPP-- 181
Query: 361 PESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEE 420
P L L + P + P SP PL L VA P P P
Sbjct: 182 --------PPPPLPPPLPSSSPIKTPLVSPPGPLTKGNLPV--VAPPVPCAPPPPPPPPP 231
Query: 421 FQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSS-- 478
P P + L+ + + +P + P P LP G+ L +
Sbjct: 232 PTPPPLPPASVLSDKAVKPQLAP-----------LHLP-PIPPPLPLLPPCGYPGLKAEP 279
Query: 479 SEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAA--PLAVLP 536
+ P+QD + P P +P P P +P V ++ P + P
Sbjct: 280 ASPAQDAQEPPAPPPPLPPYASCSPRASLPAPP-----------LPGVNSSSETPPPLPP 328
Query: 537 MEP---LPPEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPST-- 591
P PP+ AL P A P + PG G+ A + P+T
Sbjct: 329 KSPSFQAPPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARSPTTEL 388
Query: 592 ----QTLSLWAPT 600
Q + W PT
Sbjct: 389 SSKSQQATAWTPT 401
Score = 33.9 bits (76), Expect = 0.49
Identities = 36/137 (26%), Positives = 51/137 (37%), Gaps = 15/137 (10%)
Query: 205 PPASTAALRTTPSPPSPG---PETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDAL 261
PP L+ P+ P+ P PP +PP AS A+ PA P
Sbjct: 268 PPCGYPGLKAEPASPAQDAQEPPAPPPPLPPYASCSPRASLPAPPLPGVNSSSETPPPLP 327
Query: 262 AKKGLGPFLQTAKPARRGQTSASILPR------VVQAQRGPQPPPGEAGIPGHPTPPATL 315
K P Q A P + G + P +Q +R +P G + P PPA
Sbjct: 328 PK---SPSFQ-APPQKAGAQALPAPPAPPGSQPFLQKKRHGRPGAGGGKLNPPPAPPARS 383
Query: 316 PSEPV--EGVQASPWRP 330
P+ + + QA+ W P
Sbjct: 384 PTTELSSKSQQATAWTP 400
Score = 33.5 bits (75), Expect = 0.64
Identities = 68/271 (25%), Positives = 86/271 (31%), Gaps = 36/271 (13%)
Query: 296 PQPPPGEAGIPGHP----TPPATLPSEPVEGVQASPWR-----PRPVLPTHPALTLPVSS 346
P PPP +P P PP PS P S R R L +
Sbjct: 2 PVPPPPPPPLPPPPPPLGAPPPPPPSAPPVSTDTSSLRRADPKGRSALLADIQQGTRLRK 61
Query: 347 DASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAA 406
AP+ E + G T G T P + G P +LR DVA
Sbjct: 62 VTQINDRSAPQIESSKGTNKEGGGSANTRGAST-PPTLGDLFAGGFP-VLRPAGQRDVAG 119
Query: 407 PEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSP--GEPQETCSGTEVERPRQTGPG 464
G+ GQ P R T++ L+ SP G E PR P
Sbjct: 120 -----GKTGQGPGSRAPSPRLPNKTISG-PLIPPASPRLGNTSEAHGAARTAPPRPNVPA 173
Query: 465 LPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMP 524
P P+ P L + TP V P P L+ G P
Sbjct: 174 PP-------------PPTPPPPPPPLPPPLPSSSPIKTPLVSPPGP---LTKGNLPVVAP 217
Query: 525 RVRLAAPLAVLPMEPLPPEPVRPAALLTPEA 555
V A P P P PP P+ PA++L+ +A
Sbjct: 218 PVPCAPPPPPPPPPPTPP-PLPPASVLSDKA 247
>gi|146219843 Snf2-related CBP activator protein [Homo sapiens]
Length = 3230
Score = 56.6 bits (135), Expect = 7e-08
Identities = 115/477 (24%), Positives = 165/477 (34%), Gaps = 53/477 (11%)
Query: 205 PPASTAALRTTPSPPS------PGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPS 258
P +ST ++ + S P P P + P +P +A V A+GPA ++ L
Sbjct: 1426 PVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVP 1485
Query: 259 DALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPP----PGEAGIPG--HPTPP 312
A L P A P+ T + + + P P P + +PG P
Sbjct: 1486 AAPGPPSLAP--SGASPSASALTLGLATAPSLSSSQTPGHPLLLAPTSSHVPGLNSTVAP 1543
Query: 313 ATLPSEPVEGVQASPWRPRP-VLPTHPALTLPVSSDASS-PSPPAPRPERPESLLVSGPS 370
A P ASP+ P P +L P SS + + +P AP ++L P+
Sbjct: 1544 ACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAILAPSPA 1603
Query: 371 VTLTEGLGTVRPEQDPAKSPG-SPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWR 429
L P A SPG +P+L + V AP G AS P P
Sbjct: 1604 PPLA-------PLPVLAPSPGAAPVLASSQTPVPVMAPSSTPG-TSLASASPVPAPTPVL 1655
Query: 430 ATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPG 489
A + + ++ P S + P L + L + P
Sbjct: 1656 APSSTQTMLPAPVPSPLPSPASTQTLALAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQT 1715
Query: 490 LSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAA 549
LS+ PA + V P + L+ GP L + LA + P P+ P P
Sbjct: 1716 LSLTPA------SSLVPTPAQTLSLAPGPPLGPTQTLSLAPAPPLAPASPVGPAPAHTLT 1769
Query: 550 LLTPEAS-SVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTLSLWAPTGVLLPSLV 608
L +S S+ P + L +P PV T P + QTL+L AP P+
Sbjct: 1770 LAPASSSASLLAPASVQTLTLSPA-PV--------PTLGPAAAQTLAL-APASTQSPASQ 1819
Query: 609 ELEYPFQAGRGASLQQELT--------EP-TLALSAESHRPPELQDSVEGLSERPSR 656
A A L + EP TL L + PP S G RP R
Sbjct: 1820 ASSLVVSASGAAPLPVTMVSRLPVSKDEPDTLTLRSGPPSPPSTATSFGG--PRPRR 1874
Score = 48.5 bits (114), Expect = 2e-05
Identities = 100/425 (23%), Positives = 146/425 (34%), Gaps = 126/425 (29%)
Query: 204 EPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAK 263
E P+ST +T + P PGPET P + P L +HRP+
Sbjct: 2879 EAPSSTLKGKTNGADPVPGPETLIVADPVLEPQLIPGPQP-----LGPQPVHRPN----- 2928
Query: 264 KGLGPFLQTAKPARRGQTSASI---LPRVVQA------QRGPQPPPGEAGIPGHPTPPAT 314
P L + RRG+ + +P + + + QPPP HP+P
Sbjct: 2929 ----PLLSPVEKRRRGRPPKARDLPIPGTISSAGDGNSESRTQPPP-------HPSPLTP 2977
Query: 315 LPSEPVEGVQASPWRPRPVLPTHP-ALTLPVSSDASSP----------SPPAPRPERPES 363
LP P V PT A T+ + ++SP +PP+PRP +
Sbjct: 2978 LP-------------PLLVCPTATVANTVTTVTISTSPPKRKRGRPPKNPPSPRPSQLPV 3024
Query: 364 LLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQP 423
L SV + GLG R Q +S G SS D E G +P
Sbjct: 3025 LDRDSTSVLESCGLGRRRQPQGQGESEG--------SSSD---------EDGS-----RP 3062
Query: 424 LARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEP-S 482
L R R L AE + R R++G + + +DL+ S P
Sbjct: 3063 LTRLARLRLEAEGM-------------------RGRKSGGSMVVAVIQDDLDLADSGPGG 3103
Query: 483 QDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLP-----M 537
++ P +S+ P +T P P E +PR R AP+ P
Sbjct: 3104 LELTPPVVSLTPKLRSTRLRPGSLVPP--------LETEKLPRKRAGAPVGGSPGLAKRG 3155
Query: 538 EPLPPEPVRPAALLTPEASSVGGPDQARYLESAPGWP------------VGQEEWGVAHT 585
PP P+ P + + G + E G P Q + + +
Sbjct: 3156 RLQPPSPLGPEGSVEESEAEASGEE-----EEGDGTPRRRPGPRRLVGTTNQGDQRILRS 3210
Query: 586 SSPPS 590
S+PPS
Sbjct: 3211 SAPPS 3215
Score = 43.1 bits (100), Expect = 8e-04
Identities = 117/505 (23%), Positives = 173/505 (34%), Gaps = 93/505 (18%)
Query: 210 AALRTTPSPPSPGPETP----PAGVPPAA-SSQVWAAGPAAQEWLSRDLLHRPSDALAKK 264
A L P P PGPE P VP +S + +A PA P A +
Sbjct: 1017 APLGPVPVRPPPGPELSAQPTPGPVPQVLPASLMVSASPAG-----------PPLIPASR 1065
Query: 265 GLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQ 324
GP L Q ++ LP+V+ P P +G PTP +L P V+
Sbjct: 1066 PPGPVLLPPL-----QPNSGSLPQVL-----PSPLGVLSGTSRPPTPTLSLKPTPPAPVR 1115
Query: 325 ASPWRP-------RPVLPTHPALTLP---------VSSDASSPSPPAPRPERPESLLVSG 368
SP P +P L P T P ++ A++ + PAP P P+ L++S
Sbjct: 1116 LSPAPPPGSSSLLKP-LTVPPGYTFPPAAATTTSTTTATATTTAVPAPTP-APQRLILS- 1172
Query: 369 PSVTLTEGLGTV-----------RPEQDPAKS-------PGSPLLLRGLSSGDVAA--PE 408
P + G V RP + S G+ L L G +A P
Sbjct: 1173 PDMQARLPSGEVVSIGQLASLAQRPVANAGGSKPLTFQIQGNKLTLTGAQVRQLAVGQPR 1232
Query: 409 PIMGEP---GQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGL 465
P+ A + +++P L + + P S T P TG L
Sbjct: 1233 PLQRNVVHLVSAGGQHHLISQPAHVAL-IQAVAPTPGPTPVSVLPSSTPSTTPAPTGLSL 1291
Query: 466 PREGAR---------GHMDLSSSEPSQDIEGPGLSILPA-RDATFSTPSVRQPDPSAWLS 515
P + G + + + +D P + PA R + P+V P P+
Sbjct: 1292 PLAANQVPPTMVNNTGVVKIVVRQAPRDGLTPVPPLAPAPRPPSSGLPAVLNPRPTLTPG 1351
Query: 516 SGPELT-GMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEASSVGGPDQARYLESAPG-- 572
P T G R + P V P+ L P + P A+ + S PG
Sbjct: 1352 RLPTPTLGTARAPMPTPTLVRPLLKLVHSPSPEVSASAPGAAPLTISSPLHVPSSLPGPA 1411
Query: 573 ---WPVGQEE---WGVAHTSSPPSTQTLSLWAPTGVLLPSLVELEYPFQA-----GRGAS 621
P+ V+ T S P + +L + PT + P+ L P A G +
Sbjct: 1412 SSPMPIPNSSPLASPVSSTVSVPLSSSLPISVPTTLPAPASAPLTIPISAPLTVSASGPA 1471
Query: 622 LQQELTEPTLALSAESHRPPELQDS 646
L +T P + + PP L S
Sbjct: 1472 LLTSVTPPLAPVVPAAPGPPSLAPS 1496
Score = 41.2 bits (95), Expect = 0.003
Identities = 83/365 (22%), Positives = 128/365 (35%), Gaps = 49/365 (13%)
Query: 205 PPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAG----------PAAQEWLSRDLL 254
PP+ + P P PPA PP A + + P + + L
Sbjct: 2487 PPSQIPPCSSPACTPPPACTPPPAHTPPPAQTCLVTPSSPLLLGPPSVPISASVTNLPLG 2546
Query: 255 HRPSDALAKKGLG--PFLQTAKPARRGQTSASIL-PRVVQAQRGPQPPPGEAGIPGHPTP 311
RP L + L L+ A A +S S++ P+ + P E + P+
Sbjct: 2547 LRPEAELCAQALASPESLELASVASSETSSLSLVPPKDLLPVAVEILPVSEKNLSLTPSA 2606
Query: 312 PA------TLPS-EPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERP--E 362
P+ ++P+ + E ++ VLP L L VS PP+ + P E
Sbjct: 2607 PSLTLEAGSIPNGQEQEAPDSAEGTTLTVLPEGEELPLCVSESNGLELPPSAASDEPLQE 2666
Query: 363 SLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQ 422
L S LTE + P SP P + L + +VAAP +S E
Sbjct: 2667 PLEADRTSEELTEA-------KTPTSSPEKP---QELVTAEVAAPS--TSSSATSSPEGP 2714
Query: 423 PLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPS 482
ARP R +A+ + + G P + G +V R LP +
Sbjct: 2715 SPARPPRRRTSADVEIRGQGTGRPGQP-PGPKVLRK------LPGRLVTVVEEKELVRRR 2767
Query: 483 QDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPP 542
+ G +++P T ++P PS SGPE + + P P LP
Sbjct: 2768 RQQRGAASTLVPGVSETSASPG----SPSVRSMSGPESS----PPIGGPCEAAPSSSLPT 2819
Query: 543 EPVRP 547
P +P
Sbjct: 2820 PPQQP 2824
Score = 39.7 bits (91), Expect = 0.009
Identities = 109/440 (24%), Positives = 140/440 (31%), Gaps = 127/440 (28%)
Query: 303 AGIPGHPTPPATLPSE-----PVEGVQASPWRPRPVLPTHPALTLPVS-------SDASS 350
A PG PTP + LPS P + P V PT T V D +
Sbjct: 1264 APTPG-PTPVSVLPSSTPSTTPAPTGLSLPLAANQVPPTMVNNTGVVKIVVRQAPRDGLT 1322
Query: 351 PSPP---APRPERPESLLVSGPSVTLTEG------LGTVR-PEQDP-------------- 386
P PP APRP V P TLT G LGT R P P
Sbjct: 1323 PVPPLAPAPRPPSSGLPAVLNPRPTLTPGRLPTPTLGTARAPMPTPTLVRPLLKLVHSPS 1382
Query: 387 ----AKSPG-------SPLLLRGLSSGDVAAPEPIMGE---------------------- 413
A +PG SPL + G ++P PI
Sbjct: 1383 PEVSASAPGAAPLTISSPLHVPSSLPGPASSPMPIPNSSPLASPVSSTVSVPLSSSLPIS 1442
Query: 414 -----PGQASEEFQ-PLARPWRATLAAEELVSH----------RSPGEPQETCSGTEVER 457
P AS P++ P + + L++ +PG P SG
Sbjct: 1443 VPTTLPAPASAPLTIPISAPLTVSASGPALLTSVTPPLAPVVPAAPGPPSLAPSGASPSA 1502
Query: 458 PR-----QTGPGLPREGARGHMDLSSSEPSQDIEGPGLS----------ILPARDATFST 502
T P L GH L + S PGL+ ++PA
Sbjct: 1503 SALTLGLATAPSLSSSQTPGHPLLLAPTSS---HVPGLNSTVAPACSPVLVPASALASPF 1559
Query: 503 PSVRQPDPS-----AWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAALLTPEASS 557
PS P P+ A SS + P +AAP + + P P P+ P +L P
Sbjct: 1560 PSAPNPAPAQASLLAPASSASQALATPLAPMAAPQTAI-LAPSPAPPLAPLPVLAPSPG- 1617
Query: 558 VGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTLS---LWAPTGVLLPSLVELEYPF 614
+AP Q V SS P T S + APT VL PS + P
Sbjct: 1618 -----------AAPVLASSQTPVPVMAPSSTPGTSLASASPVPAPTPVLAPSSTQTMLP- 1665
Query: 615 QAGRGASLQQELTEPTLALS 634
A + L + TLAL+
Sbjct: 1666 -APVPSPLPSPASTQTLALA 1684
Score = 35.8 bits (81), Expect = 0.13
Identities = 56/223 (25%), Positives = 79/223 (35%), Gaps = 34/223 (15%)
Query: 184 MAAPVLWTVESFFQCVGSGTEPPASTAALRTTPSPPSPGPETPPAG-VPPAASSQVWAAG 242
+ AP V V P A+ +P P +P P A + PA+S+ A
Sbjct: 1526 LLAPTSSHVPGLNSTVAPACSPVLVPASALASPFPSAPNPAPAQASLLAPASSASQALAT 1585
Query: 243 PAAQEWLSRDLLHRPSDALAKKGLGPF-LQTAKPARRGQTSASILPRVVQAQRGPQPPPG 301
P A + + PS A L P + P ++S P V A P PG
Sbjct: 1586 PLAPMAAPQTAILAPSPA---PPLAPLPVLAPSPGAAPVLASSQTPVPVMA---PSSTPG 1639
Query: 302 EAGIPGHPTPPATLPSEPVEGVQASPWRPRPVL-PTHPALTLPVSSDASSPSPPAPR--- 357
+ P P P PVL P+ LP + PSP + +
Sbjct: 1640 TSLASASPVP-----------------APTPVLAPSSTQTMLPAPVPSPLPSPASTQTLA 1682
Query: 358 --PERPESLLVSGPSVTLTEGLGTVR---PEQDPAKSPGSPLL 395
P +L S PS TL+ G G + P Q + +P S L+
Sbjct: 1683 LAPALAPTLGGSSPSQTLSLGTGNPQGPFPTQTLSLTPASSLV 1725
Score = 32.3 bits (72), Expect = 1.4
Identities = 44/147 (29%), Positives = 52/147 (35%), Gaps = 24/147 (16%)
Query: 296 PQPPPGEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPA 355
P+P P A P PA +P V S P +LP H LP SP PP+
Sbjct: 2441 PRPRPTPASAPA--AIPALVPVPVSAPVPISAPNPITILPVH---ILP------SPPPPS 2489
Query: 356 PRPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPG 415
P P+ T T P Q +P SPLLL P + P
Sbjct: 2490 QIPPCSSPACTPPPACT-PPPAHTPPPAQTCLVTPSSPLLL---------GPPSV---PI 2536
Query: 416 QASEEFQPLARPWRATLAAEELVSHRS 442
AS PL A L A+ L S S
Sbjct: 2537 SASVTNLPLGLRPEAELCAQALASPES 2563
Score = 32.0 bits (71), Expect = 1.9
Identities = 40/137 (29%), Positives = 50/137 (36%), Gaps = 35/137 (25%)
Query: 288 RVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSD 347
R V P+ P G +P P P L ++P G PV PA + +S
Sbjct: 1007 RTVVVVNNPRAPLGP--VPVRPPPGPELSAQPTPG---------PVPQVLPASLMVSASP 1055
Query: 348 ASSPSPPAPRPERPESLLVSGP-SVTLTEGL--------GTVRP---------------E 383
A P PA RP P L P S +L + L GT RP
Sbjct: 1056 AGPPLIPASRPPGPVLLPPLQPNSGSLPQVLPSPLGVLSGTSRPPTPTLSLKPTPPAPVR 1115
Query: 384 QDPAKSPGSPLLLRGLS 400
PA PGS LL+ L+
Sbjct: 1116 LSPAPPPGSSSLLKPLT 1132
>gi|222352122 hypothetical protein LOC284297 [Homo sapiens]
Length = 1573
Score = 54.7 bits (130), Expect = 3e-07
Identities = 97/407 (23%), Positives = 139/407 (34%), Gaps = 65/407 (15%)
Query: 294 RGPQPPP-----GEAGIPGHPTP------PA---TLPSEPVEGVQASPWRPRPVLPT--- 336
R P PP G+ G P P P PA T P P G ASP P P L +
Sbjct: 968 RSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASPGPPGPALTSDSS 1027
Query: 337 -----HPALTLPVSSDASSPSPPAPRP--ERPESLLVSGPSVTLTEGLGTVRPEQDPAKS 389
H ALT +SDA SPP P P L+++ P L+ +V P P S
Sbjct: 1028 RELTPHSALTSEATSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSVVPALTPEPS 1087
Query: 390 PGS-PLLLRGLSS-----GDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSP 443
P P L + L+S +V + P + ++ P+ +T++ SP
Sbjct: 1088 PTPLPTLPKELTSDPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSP 1147
Query: 444 G-EPQETCSGTEVERPRQT--------GPGLPREGARGHMDLSSSEPSQDIEGPGLSILP 494
P T T P T P P H ++ S I P + P
Sbjct: 1148 SPHPTTTPDPTMAPDPITTLNPTVTPHFPTTPHPTTTPHP--TTITHSTMIPDPTTTPQP 1205
Query: 495 ARDATFST---PSVRQPDPSAWL-------SSGPELTGMPRVRLAAPLAVLPMEPLPPEP 544
T ST P P + S+ P T P ++P P+P
Sbjct: 1206 FTTITHSTMIPDPTTTPQPFTTMQPTTTPHSTTPHPTTTPHPTTITHSTMIPDPTTTPQP 1265
Query: 545 -------VRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAH-TSSPPSTQTLSL 596
P TP ++ P + + P + + + T++P T T
Sbjct: 1266 FTTMQPTTMPHPTTTPHPTTTPHPTTTPHPTTTPHPTMTPDPTTTPYPTTTPDPTTTPHP 1325
Query: 597 WAPTGVLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPPEL 643
P P + + P SL EL+ PTLA + + P+L
Sbjct: 1326 TTPDPSSTPVITTVSLP------TSLGTELSSPTLAPTVKPSLHPQL 1366
Score = 45.8 bits (107), Expect = 1e-04
Identities = 58/187 (31%), Positives = 69/187 (36%), Gaps = 32/187 (17%)
Query: 206 PASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKG 265
P AA RT P PSPGP P PP GPA SR+L P AL +
Sbjct: 994 PPRPAATRTAPPTPSPGPSASPG--PP---------GPALTSDSSREL--TPHSALTSEA 1040
Query: 266 LGPFLQTAKPARRGQTSAS---ILPRVVQAQRGPQ--------PPPGEAGIPGHPTPPAT 314
T+ P + + IL A P P P +P P +
Sbjct: 1041 TSDAPDTSPPTPDPASRTNPDLILTSPDFALSTPDSSVVPALTPEPSPTPLPTLPKELTS 1100
Query: 315 LPSEPVEGVQASPWRPR-PVLPTHPAL-TLPVSSDAS----SPSP-PAPRP-ERPESLLV 366
PS P E SP + P T P L T P SS S SP P P+P P P+ +
Sbjct: 1101 DPSTPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTVSEYSRSPDPSPSPHPTTTPDPTMA 1160
Query: 367 SGPSVTL 373
P TL
Sbjct: 1161 PDPITTL 1167
Score = 39.7 bits (91), Expect = 0.009
Identities = 70/275 (25%), Positives = 89/275 (32%), Gaps = 51/275 (18%)
Query: 295 GPQPPPGEAGIPGHPTPPATLPSEPVEGVQASPW---RPRPVLPTHPALTLPVSSDASSP 351
G P AG P P TL G PW RP T A P ++SP
Sbjct: 956 GKLGPTLGAGTTRSPGSPPTLRVHGDTGSPRKPWPERRPPRPAATRTAPPTPSPGPSASP 1015
Query: 352 SPPAP-------RPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDV 404
PP P R P S L S + ++ T P DPA L+ L+S D
Sbjct: 1016 GPPGPALTSDSSRELTPHSALTSEAT---SDAPDTSPPTPDPASRTNPDLI---LTSPDF 1069
Query: 405 AAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPG 464
A P + E P P +EL S P P E S
Sbjct: 1070 ALSTPDSSVVPALTPEPSPTPLP----TLPKELTS--DPSTPSEVTS------------- 1110
Query: 465 LPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMP 524
+ +S + + P L P +T S S R PDP S P T P
Sbjct: 1111 ---------LSPTSEQVPESDTTPDLDTTP-YSSTVSEYS-RSPDP----SPSPHPTTTP 1155
Query: 525 RVRLAA-PLAVLPMEPLPPEPVRPAALLTPEASSV 558
+A P+ L P P P TP +++
Sbjct: 1156 DPTMAPDPITTLNPTVTPHFPTTPHPTTTPHPTTI 1190
Score = 36.2 bits (82), Expect = 0.098
Identities = 68/273 (24%), Positives = 94/273 (34%), Gaps = 53/273 (19%)
Query: 303 AGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPE 362
AG+PGH P T G + R P + LP + D S A
Sbjct: 900 AGVPGHTLPWRTTRRP---GSSSPAIRRLPDTGSKDGYKLPWTWDTPSGRGLAEGTPTAG 956
Query: 363 SLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPE-------------- 408
L GP++ G GT R SPGSP LR GD +P
Sbjct: 957 KL---GPTL----GAGTTR-------SPGSPPTLR--VHGDTGSPRKPWPERRPPRPAAT 1000
Query: 409 ---PIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGL 465
P PG ++ P P + ++ EL H + S + P T P
Sbjct: 1001 RTAPPTPSPGPSASPGPP--GPALTSDSSRELTPHSA------LTSEATSDAP-DTSPPT 1051
Query: 466 PREGARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPR 525
P +R + DL + P + P S++PA TP +P P+ + ELT P
Sbjct: 1052 PDPASRTNPDLILTSPDFALSTPDSSVVPA-----LTP---EPSPTPLPTLPKELTSDPS 1103
Query: 526 VRLAAPLAVLPMEPLPPEPVRPAALLTPEASSV 558
E +P P TP +S+V
Sbjct: 1104 TPSEVTSLSPTSEQVPESDTTPDLDTTPYSSTV 1136
Score = 30.0 bits (66), Expect = 7.0
Identities = 48/208 (23%), Positives = 67/208 (32%), Gaps = 48/208 (23%)
Query: 203 TEPPASTAALRTTPSPPSPGPETPPA---------------------GVPPAASSQVWAA 241
T P +T TTP P +P P + P V P+ Q+
Sbjct: 1310 TPYPTTTPDPTTTPHPTTPDPSSTPVITTVSLPTSLGTELSSPTLAPTVKPSLHPQLTFT 1369
Query: 242 GPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQ---- 297
PA S+ PS AL R T+ S+ P + + P+
Sbjct: 1370 APAPHTSTSQIPTLEPSPALESS-----------PSRSSTATSMDPLSTEDFKPPRSQSP 1418
Query: 298 ---PPPGEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTL-PVSSDASSPSP 353
PPP H T+ +P+ A P P+ P LTL P + P
Sbjct: 1419 NLTPPPTHT---PHSASDLTVSPDPLLSPTAHPLDHPPLDP----LTLGPTPGQSPGPHG 1471
Query: 354 PAPRPERPESLLVSGPSVTLTEGLGTVR 381
P P P ++ P L E + VR
Sbjct: 1472 PCVAPTPPVRVMACEPP-ALVELVAAVR 1498
Score = 29.6 bits (65), Expect = 9.2
Identities = 33/121 (27%), Positives = 46/121 (38%), Gaps = 5/121 (4%)
Query: 214 TTPSPPSPGPETPPAGVPPAASSQVWAA-GPAAQEWLSRDLLHRPSDALAKKGLGPFLQT 272
TT P P + A PP +SQ AA A + + RP+ ++ T
Sbjct: 640 TTQPPVMPTTKHSRAQSPPDLTSQTTAALTTEASRRPTSEFTRRPTTEAPQRWTSHTTAT 699
Query: 273 AKP-ARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQASPWRPR 331
P A R +T+ ++ Q GPQ E+ I P +E EG SP P
Sbjct: 700 LTPQAPRERTTKTMAMLTTQ---GPQEMTSESTIKSIPQASLEPSAEIPEGSPESPKDPA 756
Query: 332 P 332
P
Sbjct: 757 P 757
>gi|217416350 cask-interacting protein 2 isoform b [Homo sapiens]
Length = 1120
Score = 53.9 bits (128), Expect = 5e-07
Identities = 120/452 (26%), Positives = 150/452 (33%), Gaps = 77/452 (17%)
Query: 241 AGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRV-----VQAQRG 295
AGP + +L A+A G P P R + SI R Q Q
Sbjct: 578 AGPRLLTFQGSELSPELQAAMAGGGPEPL---PLPPARSPSQESIGARSRGSGHSQEQPA 634
Query: 296 PQP------PPGEAGIP-GHPTPPATLPSEPVEGV--------QASPWRPRPVLPTHP-- 338
PQP PP E +P G PP S P +G Q SP P P P
Sbjct: 635 PQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPW 694
Query: 339 ALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLG------TVRPEQDPAKSPGS 392
A + A+ P PP P+ R SL GP+ EG T+ + PG
Sbjct: 695 AFSYLAGPPATPPDPPRPK-RRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGR 753
Query: 393 PLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSG 452
L+R S P P G P S+ F AR + +S S P+
Sbjct: 754 SALVRTSPS---VTPTPARGTP--RSQSFALRARRKGPPPPPPKRLSSVSGPSPEPP--- 805
Query: 453 TEVERPRQTGPGLPREGARGHMDLSSSEPSQDIE--GPGLSILPARDATFSTPSVRQPDP 510
P PG P+EGA G + SEP+ E GP PA D P P
Sbjct: 806 -----PLDESPG-PKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPP 859
Query: 511 SAWLSSGPELTGMPRVRLA-----APLAVLPME-PLPP---------------------E 543
S SSG L L P P E P+PP E
Sbjct: 860 SRG-SSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCRERE 918
Query: 544 PVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTLSLWAPTGVL 603
P++ A L AS+ GP A PG SS P+ + AP+ +
Sbjct: 919 PLQTALLAFGVASATPGP-AAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAM 977
Query: 604 LPSLVELEYPFQAGRGASLQQELTEPTLALSA 635
P + P AS TEP A +A
Sbjct: 978 QPPVPPCPGPGLESSAASRWNGETEPPAAPAA 1009
Score = 44.3 bits (103), Expect = 4e-04
Identities = 108/423 (25%), Positives = 148/423 (34%), Gaps = 115/423 (27%)
Query: 249 LSRDLLHRPSDALAKKGL----GPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAG 304
L R LL +AL++ G GP L + G+ A+ PR++ Q P +A
Sbjct: 540 LRRGLLQ--GEALSEGGRRLAKGPELMAIEGLENGEGPATAGPRLLTFQGSELSPELQAA 597
Query: 305 IPGH-----PTPPATLPSEPVEGVQA-----SPWRPRPVLPTHPALTLPVSSDASSPSPP 354
+ G P PPA PS+ G ++ S +P P PSPP
Sbjct: 598 MAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAP------------QPSGGDPSPP 645
Query: 355 APRPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGS--PLLLRGLSSGDVAAPEPIMG 412
R PE GT RP + + PG P + G ++P P G
Sbjct: 646 QER-NLPE---------------GTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAP--G 687
Query: 413 EPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARG 472
P A F LA P P P + RP++ L R G
Sbjct: 688 PPPGAPWAFSYLAGP---------------PATPPDP------PRPKRRSHSLSRPGP-- 724
Query: 473 HMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELT-----GMPRVR 527
+ + + EGP S L +++T R+P SA + + P +T G PR +
Sbjct: 725 ----TEGDAEGEAEGPVGSTL----GSYAT-LTRRPGRSALVRTSPSVTPTPARGTPRSQ 775
Query: 528 LAAPLAVLPMEPLPPEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSS 587
A L P PP P R SSV GP +P P E G ++
Sbjct: 776 SFA-LRARRKGPPPPPPKR--------LSSVSGP--------SPEPPPLDESPGPKEGAT 818
Query: 588 PPSTQTLSLWAPTGVLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPPELQDSV 647
P +TLS P G P P AG + ++E P PP S
Sbjct: 819 GPRRRTLS--EPAGPSEPP----GPPAPAGPASDTEEEEPGP-------EGTPPSRGSSG 865
Query: 648 EGL 650
EGL
Sbjct: 866 EGL 868
Score = 38.5 bits (88), Expect = 0.020
Identities = 52/208 (25%), Positives = 69/208 (33%), Gaps = 23/208 (11%)
Query: 212 LRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKGLGPFLQ 271
++ P P P P P VPP + + + R R + L L +
Sbjct: 878 IKQRPKPAGPPPRETP--VPPGLDFNL-----TESDTVKRRPKCREREPLQTALLAFGVA 930
Query: 272 TAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTP----PATLPSEP------VE 321
+A P + A PQP P G PTP PA P P +E
Sbjct: 931 SATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLE 990
Query: 322 GVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTV- 380
AS W P PA L V ++P P + + L SGP + G V
Sbjct: 991 SSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQ---LAFSGPKLAPRLGPRPVP 1047
Query: 381 --RPEQDPAKSPGSPLLLRGLSSGDVAA 406
RPE PG +S +AA
Sbjct: 1048 PPRPESTGTVGPGQAQQRLEQTSSSLAA 1075
>gi|217416347 cask-interacting protein 2 isoform a [Homo sapiens]
Length = 1202
Score = 53.9 bits (128), Expect = 5e-07
Identities = 120/452 (26%), Positives = 150/452 (33%), Gaps = 77/452 (17%)
Query: 241 AGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARRGQTSASILPRV-----VQAQRG 295
AGP + +L A+A G P P R + SI R Q Q
Sbjct: 660 AGPRLLTFQGSELSPELQAAMAGGGPEPL---PLPPARSPSQESIGARSRGSGHSQEQPA 716
Query: 296 PQP------PPGEAGIP-GHPTPPATLPSEPVEGV--------QASPWRPRPVLPTHP-- 338
PQP PP E +P G PP S P +G Q SP P P P
Sbjct: 717 PQPSGGDPSPPQERNLPEGTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAPGPPPGAPW 776
Query: 339 ALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLG------TVRPEQDPAKSPGS 392
A + A+ P PP P+ R SL GP+ EG T+ + PG
Sbjct: 777 AFSYLAGPPATPPDPPRPK-RRSHSLSRPGPTEGDAEGEAEGPVGSTLGSYATLTRRPGR 835
Query: 393 PLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSG 452
L+R S P P G P S+ F AR + +S S P+
Sbjct: 836 SALVRTSPS---VTPTPARGTP--RSQSFALRARRKGPPPPPPKRLSSVSGPSPEPP--- 887
Query: 453 TEVERPRQTGPGLPREGARGHMDLSSSEPSQDIE--GPGLSILPARDATFSTPSVRQPDP 510
P PG P+EGA G + SEP+ E GP PA D P P
Sbjct: 888 -----PLDESPG-PKEGATGPRRRTLSEPAGPSEPPGPPAPAGPASDTEEEEPGPEGTPP 941
Query: 511 SAWLSSGPELTGMPRVRLA-----APLAVLPME-PLPP---------------------E 543
S SSG L L P P E P+PP E
Sbjct: 942 SRG-SSGEGLPFAEEGNLTIKQRPKPAGPPPRETPVPPGLDFNLTESDTVKRRPKCRERE 1000
Query: 544 PVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTLSLWAPTGVL 603
P++ A L AS+ GP A PG SS P+ + AP+ +
Sbjct: 1001 PLQTALLAFGVASATPGP-AAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAM 1059
Query: 604 LPSLVELEYPFQAGRGASLQQELTEPTLALSA 635
P + P AS TEP A +A
Sbjct: 1060 QPPVPPCPGPGLESSAASRWNGETEPPAAPAA 1091
Score = 44.3 bits (103), Expect = 4e-04
Identities = 108/423 (25%), Positives = 148/423 (34%), Gaps = 115/423 (27%)
Query: 249 LSRDLLHRPSDALAKKGL----GPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAG 304
L R LL +AL++ G GP L + G+ A+ PR++ Q P +A
Sbjct: 622 LRRGLLQ--GEALSEGGRRLAKGPELMAIEGLENGEGPATAGPRLLTFQGSELSPELQAA 679
Query: 305 IPGH-----PTPPATLPSEPVEGVQA-----SPWRPRPVLPTHPALTLPVSSDASSPSPP 354
+ G P PPA PS+ G ++ S +P P PSPP
Sbjct: 680 MAGGGPEPLPLPPARSPSQESIGARSRGSGHSQEQPAP------------QPSGGDPSPP 727
Query: 355 APRPERPESLLVSGPSVTLTEGLGTVRPEQDPAKSPGS--PLLLRGLSSGDVAAPEPIMG 412
R PE GT RP + + PG P + G ++P P G
Sbjct: 728 QER-NLPE---------------GTERPPKLCSSLPGQGPPPYVFMYPQGSPSSPAP--G 769
Query: 413 EPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARG 472
P A F LA P P P + RP++ L R G
Sbjct: 770 PPPGAPWAFSYLAGP---------------PATPPDP------PRPKRRSHSLSRPGP-- 806
Query: 473 HMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELT-----GMPRVR 527
+ + + EGP S L +++T R+P SA + + P +T G PR +
Sbjct: 807 ----TEGDAEGEAEGPVGSTL----GSYAT-LTRRPGRSALVRTSPSVTPTPARGTPRSQ 857
Query: 528 LAAPLAVLPMEPLPPEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSS 587
A L P PP P R SSV GP +P P E G ++
Sbjct: 858 SFA-LRARRKGPPPPPPKR--------LSSVSGP--------SPEPPPLDESPGPKEGAT 900
Query: 588 PPSTQTLSLWAPTGVLLPSLVELEYPFQAGRGASLQQELTEPTLALSAESHRPPELQDSV 647
P +TLS P G P P AG + ++E P PP S
Sbjct: 901 GPRRRTLS--EPAGPSEPP----GPPAPAGPASDTEEEEPGP-------EGTPPSRGSSG 947
Query: 648 EGL 650
EGL
Sbjct: 948 EGL 950
Score = 38.5 bits (88), Expect = 0.020
Identities = 52/208 (25%), Positives = 69/208 (33%), Gaps = 23/208 (11%)
Query: 212 LRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKGLGPFLQ 271
++ P P P P P VPP + + + R R + L L +
Sbjct: 960 IKQRPKPAGPPPRETP--VPPGLDFNL-----TESDTVKRRPKCREREPLQTALLAFGVA 1012
Query: 272 TAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTP----PATLPSEP------VE 321
+A P + A PQP P G PTP PA P P +E
Sbjct: 1013 SATPGPAAPLPSPTPGESPPASSLPQPEPSSLPAQGVPTPLAPSPAMQPPVPPCPGPGLE 1072
Query: 322 GVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTV- 380
AS W P PA L V ++P P + + L SGP + G V
Sbjct: 1073 SSAASRWNGETEPPAAPAALLKVPGAGTAPKPVSVACTQ---LAFSGPKLAPRLGPRPVP 1129
Query: 381 --RPEQDPAKSPGSPLLLRGLSSGDVAA 406
RPE PG +S +AA
Sbjct: 1130 PPRPESTGTVGPGQAQQRLEQTSSSLAA 1157
>gi|118421085 leucine-rich repeat kinase 1 [Homo sapiens]
Length = 1910
Score = 53.9 bits (128), Expect = 5e-07
Identities = 137/574 (23%), Positives = 202/574 (35%), Gaps = 143/574 (24%)
Query: 202 GTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLS--RDLLHRPSD 259
GT+PP T P + PE+P PP +S+ +E L+ RD L P
Sbjct: 1200 GTQPPGFLPNC-TWPHSVNSSPESPSCPAPPTSST-----AQPRRECLTPIRDPLRTPPR 1253
Query: 260 ALAKKGLGPFLQTAKP-----ARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPAT 314
A A G P QT + A R + A L +A + P+ P P P
Sbjct: 1254 AAAFMGT-PQNQTHQQPHVLRAARAEEPAQKLKD--KAIKTPKRPGNSTVTSSPPVTPKK 1310
Query: 315 LPSEPVEGV-QASPWRPR---------------------------PVLPTHPALTLPVSS 346
L + P+ V + SP+R PV T P L+ +
Sbjct: 1311 LFTSPLCDVSKKSPFRKSKIECPSPGELDQKEPQMSPSVAASLSCPVPSTPPELSQRATL 1370
Query: 347 DASSPSPPAPRPER-------PESLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGL 399
D P PP+ +R S++ P + T G+GT PA S +GL
Sbjct: 1371 DTVPPPPPSKVGKRCRKTSDPRRSIVECQPDASATPGVGTA---DSPAAPTDSRDDQKGL 1427
Query: 400 SSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEEL-----VSHRSPGEPQETCSGTE 454
S + PE G PG + P T E + H G+ + E
Sbjct: 1428 SLSPQSPPER-RGYPGPGLRSDWHASSPLLITSDTEHVTLLSEAEHHGIGDLKSNVLSVE 1486
Query: 455 VERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWL 514
+T + + H + S PS GPG ++P+RD +T RQ SA L
Sbjct: 1487 EGEGLRTADA--EKSSLSHPGIPPSPPSC---GPGSPLMPSRDVHCTTDG-RQCQASAQL 1540
Query: 515 SSGP---------------------ELTGMPRVRLAA--PLAVLPMEPLPPE-------- 543
+ P + +G+P++R+ P + L EPL E
Sbjct: 1541 DNLPASAWHSTDSASPQTYEVELEMQASGLPKLRIKKIDPSSSLEAEPLSKEESSLGEES 1600
Query: 544 -------PVRPAALLTPEASSVGGPDQARYLESAPGWPVGQ--------EEWGVAHTSSP 588
P +L PE + V P R S PG GQ G + T SP
Sbjct: 1601 FLPALSMPRASRSLSKPEPTYV-SPPCPRLSHSTPGKSRGQTYICQACTPTHGPSSTPSP 1659
Query: 589 PSTQTLSLWAP----TGVLLPSLVELEYP-----------FQAGRG----------ASLQ 623
T + W P +G P +++ ++P +GRG + L+
Sbjct: 1660 FQTDGVP-WTPSPKHSGKTTPDIIK-DWPRRKRAVGCGAGSSSGRGEVGADLPGSLSLLE 1717
Query: 624 QELTEPTLALSAESHRPPELQD-SVEGLSERPSR 656
E + L LS HR P L+D +EG+ + P +
Sbjct: 1718 SEGKDHGLELSI--HRTPILEDFELEGVCQLPDQ 1749
>gi|85815829 SH3-domain binding protein 1 [Homo sapiens]
Length = 701
Score = 53.5 bits (127), Expect = 6e-07
Identities = 54/202 (26%), Positives = 79/202 (39%), Gaps = 18/202 (8%)
Query: 216 PSPPSPGPETPPAGVP-PAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKG----LGPFL 270
PS P P T PA P PA + A A +E ++ RP+ + P
Sbjct: 500 PSTAVPTPATTPAPAPAPAPAPAPALASAATKERTESEVPPRPASPKVTRSPPETAAPVE 559
Query: 271 QTAKPARRGQTSASILP--RVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGVQASPW 328
A+ +R + +P +V ++ P PP G G P P LP V +P
Sbjct: 560 DMARRTKRPAPARPTMPPPQVSGSRSSPPAPPLPPG-SGSPGTPQALPRRLVGSSLRAPT 618
Query: 329 RPRPVLPTHPALTLPVS-SDASSPSPPAPRPERPESLLVSGPSVTLTEGLGTVRPEQDPA 387
P P+ PT P S +SPSP +P P P + +S P+ LG E
Sbjct: 619 VPPPLPPTPPQPARRQSRRSPASPSPASPGPASPSPVSLSNPAQV---DLGAATAE---- 671
Query: 388 KSPGSPLLLRGLSSGDVAAPEP 409
G+P + G+ + P+P
Sbjct: 672 --GGAPEAISGVPTPPAIPPQP 691
Score = 36.6 bits (83), Expect = 0.075
Identities = 42/159 (26%), Positives = 54/159 (33%), Gaps = 14/159 (8%)
Query: 417 ASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDL 476
ASEE A P AT A +P S ER P P
Sbjct: 495 ASEELPSTAVPTPATTPAPAPAP--APAPAPALASAATKERTESEVPPRPASPKVTRSPP 552
Query: 477 SSSEPSQDIEGPGLSILPARDATFSTPSV---RQPDPSAWLSSGPELTGMPRV------- 526
++ P +D+ PAR T P V R P+ L G G P+
Sbjct: 553 ETAAPVEDMARRTKRPAPARP-TMPPPQVSGSRSSPPAPPLPPGSGSPGTPQALPRRLVG 611
Query: 527 -RLAAPLAVLPMEPLPPEPVRPAALLTPEASSVGGPDQA 564
L AP P+ P PP+P R + +P + S P A
Sbjct: 612 SSLRAPTVPPPLPPTPPQPARRQSRRSPASPSPASPGPA 650
>gi|19924099 synapsin I isoform Ia [Homo sapiens]
Length = 705
Score = 53.1 bits (126), Expect = 8e-07
Identities = 49/179 (27%), Positives = 72/179 (40%), Gaps = 21/179 (11%)
Query: 201 SGTEPPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDA 260
SG PPA + + PSP S P+ P + P Q + P A + P+
Sbjct: 494 SGLGPPAGSPLPQRLPSPTS-APQQPASQAAPPTQGQGRQSRPVAGGPGAPPAARPPASP 552
Query: 261 LAKKGLGPFLQTAKPARRGQT---SASILPRVVQAQRGPQPPPGEAG----------IP- 306
++ GP T + + G ++ P Q Q PQ PPG AG +P
Sbjct: 553 SPQRQAGPPQATRQTSVSGPAPPKASGAPPGGQQRQGPPQKPPGPAGPTRQASQAGPVPR 612
Query: 307 -GHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESL 364
G PT PS P RP+P L P+ +P + A++ PP P+ + +SL
Sbjct: 613 TGPPTTQQPRPSGP-----GPAGRPKPQLAQKPSQDVPPPATAAAGGPPHPQLNKSQSL 666
Score = 41.2 bits (95), Expect = 0.003
Identities = 60/219 (27%), Positives = 71/219 (32%), Gaps = 40/219 (18%)
Query: 200 GSGTEPPASTAALRTTPSPPSPGPET--PPAGVPPAASSQVWAAGPAAQEWLSRDLLHRP 257
G P A +T+ P P + PP G PP GP Q+ P
Sbjct: 434 GQTPSPGALPLGRQTSQQPAGPPAQQRPPPQGGPPQPGPGPQRQGPPLQQ------RPPP 487
Query: 258 SDALAKKGLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPS 317
GLGP + P R LP A PQ P +A PT S
Sbjct: 488 QGQQHLSGLGPPAGSPLPQR--------LPSPTSA---PQQPASQA---APPTQGQGRQS 533
Query: 318 EPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGL 377
PV G +P RP P P SP A P+ VSGP+ G
Sbjct: 534 RPVAGGPGAPPAARP--PASP-----------SPQRQAGPPQATRQTSVSGPAPPKASGA 580
Query: 378 --GTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEP 414
G + + P K PG R S A P P G P
Sbjct: 581 PPGGQQRQGPPQKPPGPAGPTRQASQ---AGPVPRTGPP 616
>gi|110349719 titin isoform N2-A [Homo sapiens]
Length = 33423
Score = 52.8 bits (125), Expect = 1e-06
Identities = 90/386 (23%), Positives = 133/386 (34%), Gaps = 77/386 (19%)
Query: 205 PPASTAALRTTPSPPSPGPETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKK 264
PP + P PP+ PE PP VP A P + + +K
Sbjct: 10500 PPKEVVPEKKVPVPPAKKPEAPPPKVPEA-----------------------PKEVVPEK 10536
Query: 265 GLGPFLQTAKPARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHPTPPATLPSEPVEGV- 323
+ P ++ + + +P V +A P+ EA P +PP +P P E V
Sbjct: 10537 KV-----PVPPPKKPEVPPTKVPEVPKA-AVPEKKVPEAIPPKPESPPPEVPEAPKEVVP 10590
Query: 324 -----QASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTEGLG 378
A P +P P V + P PP +PE P + + P V + E
Sbjct: 10591 EKKVPAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKVAVPE--- 10647
Query: 379 TVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPW---------- 428
PE P K P SP +VA EP P + EE +P A P
Sbjct: 10648 KKVPEAIPPK-PESPPPEVFEEPEEVALEEP----PAEVVEEPEPAAPPQVTVPPKKPVP 10702
Query: 429 ----RATLAAE-ELVSHRSPGEPQETCSGTEV--------ERPRQTGPGLPREGARGHMD 475
A +A + EL + P P+E +V E P P +P+E
Sbjct: 10703 EKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEVVPEKKV 10762
Query: 476 LSSSEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVL 535
+P ++ + +P + P+V P P S PE+ P +
Sbjct: 10763 AVPKKP--EVPPAKVPEVPKKPVLEEKPAV--PVPERAESPPPEV-------YEEPEEIA 10811
Query: 536 PMEPLPPEPVRPAALLTPEASSVGGP 561
P E + PE +P + E V P
Sbjct: 10812 PEEEIAPEEEKPVPVAEEEEPEVPPP 10837
Score = 50.4 bits (119), Expect = 5e-06
Identities = 96/435 (22%), Positives = 149/435 (34%), Gaps = 97/435 (22%)
Query: 204 EPPASTAALRTTPSPPSPGPETPPAGVP--PAAS---SQVWAAGPAAQEWLSRDLLHRPS 258
E P + P PP PE PP VP P A+ +V A P E ++ P
Sbjct: 10527 EAPKEVVPEKKVPVPPPKKPEVPPTKVPEVPKAAVPEKKVPEAIPPKPESPPPEVPEAPK 10586
Query: 259 DALAKKGLGPFLQTAKPARRGQTSASILP----RVVQAQRGPQPPPGEAGIPGHPT---- 310
+ + +K + A P ++ + + +P VV ++ P PPP + +P PT
Sbjct: 10587 EVVPEKKV-----PAAPPKKPEVTPVKVPEAPKEVVPEKKVPVPPPKKPEVP--PTKVPE 10639
Query: 311 -PPATLPSEPV-EGVQASPWRPRPVL---PTHPALTLPVSSDASSPSPPAP--------- 356
P +P + V E + P P P + P AL P + P P AP
Sbjct: 10640 VPKVAVPEKKVPEAIPPKPESPPPEVFEEPEEVALEEPPAEVVEEPEPAAPPQVTVPPKK 10699
Query: 357 -------------RPERPESLLVSGPSVTLTEG----LGTVRPEQDPAKSPGSPLLLRGL 399
+PE P + P + E + +PE PAK P P + +
Sbjct: 10700 PVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVPKEV--V 10757
Query: 400 SSGDVAAPEPIMGEPGQAS--------EEFQPLARPWRATLAAEELVSHRSPGEPQETCS 451
VA P+ P + EE + P RA E+ P+E +
Sbjct: 10758 PEKKVAVPKKPEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEIAPEEEIA 10817
Query: 452 G--------TEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARDATFSTP 503
E E P P +P EP + I + ++ +A P
Sbjct: 10818 PEEEKPVPVAEEEEPEVPPPAVP------------EEPKKIIPEKKVPVIKKPEA----P 10861
Query: 504 SVRQPDPSAWLSSGPELTGMPRVRLAAP-----------LAVLPMEPLPPEPVRPAALLT 552
++P+P + P+L P AP L +P + +P +P P +
Sbjct: 10862 PPKEPEPEKVIEK-PKLKPRPPPPPPAPPKEDVKEKIFQLKAIPKKKVPEKPQVPEKVEL 10920
Query: 553 PEASSVGGPDQARYL 567
GG + R L
Sbjct: 10921 TPLKVPGGEKKVRKL 10935
Score = 46.6 bits (109), Expect = 7e-05
Identities = 92/386 (23%), Positives = 130/386 (33%), Gaps = 55/386 (14%)
Query: 203 TEPPASTAALRTTPSPPSPGPETPPAGVP------------PAASSQVWAAGPAAQEWLS 250
T PP + P+ + PE PP VP P + A PA +
Sbjct: 10694 TVPPKKPVPEKKAPAVVAKKPELPPVKVPEVPKEVVPEKKVPLVVPKKPEAPPAKVPEVP 10753
Query: 251 RDLLHRPSDALAKKGLGPFLQTAK-PARRGQTSASILPRVVQAQRGPQPPPGEAGIPGHP 309
++++ A+ KK P + AK P + P V +R PPP P
Sbjct: 10754 KEVVPEKKVAVPKK---PEVPPAKVPEVPKKPVLEEKPAVPVPERAESPPPEVYEEPEEI 10810
Query: 310 TPPATLPSEPVEGV----QASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLL 365
P + E + V + P P P +P P +P P AP P+ PE
Sbjct: 10811 APEEEIAPEEEKPVPVAEEEEPEVPPPAVPEEPKKIIPEKKVPVIKKPEAPPPKEPE--- 10867
Query: 366 VSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASE--EFQP 423
P + + RP P P + + A P+ + E Q E E P
Sbjct: 10868 ---PEKVIEKPKLKPRPPPPPPAPPKEDVKEKIFQL--KAIPKKKVPEKPQVPEKVELTP 10922
Query: 424 LARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQ 483
L P +L+ R P EP+E V R R P E + EP +
Sbjct: 10923 LKVP-GGEKKVRKLLPERKP-EPKEEVVLKSVLRKR------PEE------EEPKVEPKK 10968
Query: 484 DIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLP-- 541
+E +P V P + PE T +P ++ A PL +P P
Sbjct: 10969 -LEKVKKPAVPEPPPPKPVEEVEVPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEA 11027
Query: 542 ------PEPVRPAALLTPEASSVGGP 561
P PV P TP A+ V P
Sbjct: 11028 EVKTIKPPPVEPEP--TPIAAPVTVP 11051
Score = 31.6 bits (70), Expect = 2.4
Identities = 44/188 (23%), Positives = 62/188 (32%), Gaps = 27/188 (14%)
Query: 305 IPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESL 364
+P P P P PV + +P P +P P +PV PPA PE P+
Sbjct: 9953 VPRKPVPEEKKPV-PVPKKKEAPPAKVPEVPKKPEEKVPVLIPKKEKPPPAKVPEVPKKP 10011
Query: 365 L------------VSGPSVTLTEGLGTVRPEQ------------DPAKSPGSPLLLRGLS 400
+ V P + E PE+ PAK P P L
Sbjct: 10012 VPEEKVPVPVPKKVEAPPAKVPEVPKKPVPEKKVPVPAPKKVEAPPAKVPEVPKKLIPEE 10071
Query: 401 SGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQ 460
P+ + P + ++ +P+ P L EE V P+E E E +
Sbjct: 10072 KKPTPVPKKVEAPPPKVPKKREPVPVP--VALPQEEEVLFEEEIVPEEEVLPEEEEVLPE 10129
Query: 461 TGPGLPRE 468
LP E
Sbjct: 10130 EEEVLPEE 10137
Score = 30.0 bits (66), Expect = 7.0
Identities = 23/83 (27%), Positives = 38/83 (45%), Gaps = 8/83 (9%)
Query: 286 LPRVVQAQRG-PQP---PPGEAGIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALT 341
+P V + +R P+P P + IP P P V+ ++ P P P P +T
Sbjct: 10991 VPTVTKRERKIPEPTKVPEIKPAIPLPAPEPKPKPEAEVKTIKPPPVEPEPT-PIAAPVT 11049
Query: 342 LPV---SSDASSPSPPAPRPERP 361
+PV ++A +P A +P+ P
Sbjct: 11050 VPVVGKKAEAKAPKEEAAKPKGP 11072
>gi|112421108 capicua homolog [Homo sapiens]
Length = 1608
Score = 52.8 bits (125), Expect = 1e-06
Identities = 121/477 (25%), Positives = 171/477 (35%), Gaps = 87/477 (18%)
Query: 156 QVQRCQEVGGTPGTQAFYRVDLSLEFAEMAAPVLWTVESFFQCVGSGTEPPASTAALRTT 215
Q+Q PGT+A A + P T F G+ T A T
Sbjct: 835 QLQVAPAPAPAPGTKA----------AAPSGPAPTTSIRFTLPPGTSTNGKVLAA---TA 881
Query: 216 PSPPSPGPETPPAGVPPAASS----QVWAAGPAAQEWLSRDL--LHRPSDALAKKGLGPF 269
P+P P ++ P+ PP A S Q G +AQ + L L PS ++ G G
Sbjct: 882 PTPGIPILQSVPSAPPPKAQSVSPVQAPPPGGSAQLLPGKVLVPLAAPSMSVRGGGAGQP 941
Query: 270 LQTAKPARRGQTSASILPRVVQAQRGPQPP-------PGEAGIPG---HPTPPATLPSEP 319
L P P V Q G QPP P P P PATLP
Sbjct: 942 LPLVSP-----------PFSVPVQNGAQPPSKIIQLTPVPVSTPSGLVPPLSPATLP--- 987
Query: 320 VEGVQASPWRPRPVLPTHPALTLPVSSDASS-PSPPAPRPERPESLLVSGPSVTLTEGLG 378
G + P + +LP+ +T S+ + P +P + ++ GP+ ++ G
Sbjct: 988 --GPTSQP--QKVLLPSSTRITYVQSAGGHALPLGTSPASSQAGTVTSYGPTSSVALGFT 1043
Query: 379 TVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLAR-PWRATLAAEEL 437
++ P P ++ L S A P++ PGQ P + P +
Sbjct: 1044 SL--------GPSGPAFVQPLLS---AGQAPLLA-PGQVGVSPVPSPQLPPACAAPGGPV 1091
Query: 438 VSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSSSEPSQDIEGPGLSILPARD 497
++ G P T S + +P Q P L A S++ P+ I G P
Sbjct: 1092 ITAFYSGSPAPT-SSAPLAQPSQAPPSLVYTVA-----TSTTPPAATILPKG----PPAP 1141
Query: 498 ATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPMEPLPPEPVRPAALLTP---- 553
AT +TP+ P PSA G L AP A P P P+ V+ A P
Sbjct: 1142 AT-ATPAPTSPFPSA-------TAGSMTYSLVAPKAQRP-SPKAPQKVKAAIASIPVGSF 1192
Query: 554 EASSVG--GPDQARYLESAPGWPVGQEEWGVAHTSSPPSTQTL-SLWAPTGVLLPSL 607
EA + G GP + LE P E + +PP+ L W PT P L
Sbjct: 1193 EAGASGRPGPAPRQPLEPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPL 1249
Score = 42.4 bits (98), Expect = 0.001
Identities = 67/253 (26%), Positives = 93/253 (36%), Gaps = 32/253 (12%)
Query: 206 PASTAALRTTPSPPSPGPETPPAGVPPAASSQV-WAAGPAAQEWLSRDLLHRPSDALAKK 264
P TA +P+P S P P+ PP+ V + P A L + P+ A A
Sbjct: 1090 PVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKG---PPAPATATP 1146
Query: 265 G-LGPF-------LQTAKPARRGQTSASILPRVVQAQRGPQPPPG-EAGIPGHPTPPATL 315
PF + + A + Q + P+ V+A P EAG G P P
Sbjct: 1147 APTSPFPSATAGSMTYSLVAPKAQRPSPKAPQKVKAAIASIPVGSFEAGASGRPGP---A 1203
Query: 316 PSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLTE 375
P +P+E P PV T P S P+PPAP P PE+ P+ +
Sbjct: 1204 PRQPLE--------PGPVREP----TAPESELEGQPTPPAP-PPLPETWT---PTARSSP 1247
Query: 376 GLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPEPIMGEPGQASEEFQPLARPWRATLAAE 435
L E+ AK P + SS D P + G+ P P A +
Sbjct: 1248 PLPPPAEERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSS 1307
Query: 436 ELVSHRSPGEPQE 448
E S R+ G+ E
Sbjct: 1308 ESSSGRAAGDTPE 1320
Score = 41.2 bits (95), Expect = 0.003
Identities = 66/262 (25%), Positives = 92/262 (35%), Gaps = 35/262 (13%)
Query: 160 CQEVGGTPGTQAFYRVDLSLEFAEMAAPVLWTVESFFQCVGSGTEPPASTAALRTTPSPP 219
C GG P AFY + + A S V + T PPA+T + P+P
Sbjct: 1084 CAAPGG-PVITAFYSGSPAPTSSAPLAQPSQAPPSLVYTVATSTTPPAATILPKGPPAPA 1142
Query: 220 SPGP-ETPPAGVPPAASSQVWAAGPAAQEWLSRDLLHRPSDALAKKGLGPFLQTAKPARR 278
+ P T P A S P AQ S + A+A +G F + R
Sbjct: 1143 TATPAPTSPFPSATAGSMTYSLVAPKAQR-PSPKAPQKVKAAIASIPVGSF-EAGASGRP 1200
Query: 279 GQTSASILPRVVQAQRGP--QPPPGEAGIPGHPTPPA--TLPSEPVEGVQASPWRPRPVL 334
G L + GP +P E+ + G PTPPA LP ++SP P P
Sbjct: 1201 GPAPRQPL------EPGPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPPLPPPAE 1254
Query: 335 -------PTHPALTLPVSSD------------ASSPSPPAPRPERPESLLVSGPSVTLTE 375
P A P SS P+PP+P P ++ G S + +
Sbjct: 1255 ERTSAKGPETMASKFPSSSSDWRVPGQGLENRGEPPTPPSPAP--APAVAPGGSSESSSG 1312
Query: 376 GLGTVRPEQDPAKSPGSPLLLR 397
PE+ A G + +R
Sbjct: 1313 RAAGDTPERKEAAGTGKKVKVR 1334
Score = 38.5 bits (88), Expect = 0.020
Identities = 36/141 (25%), Positives = 53/141 (37%), Gaps = 12/141 (8%)
Query: 257 PSDALAKKGLGPFLQTAKPARRGQTSA--SILPRVVQAQRGPQPPPGEAGIPGHPTPPAT 314
P+ + A +GLG F+ T R S++P + +Q P P EA P +
Sbjct: 10 PASSAASRGLGMFVWTNVEPRSVAVFPWHSLVPFLAPSQPDPSVQPSEAQQPASHPVASN 69
Query: 315 LPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPERPESLLVSGPSVTLT 374
EP E + RP + P A+ P P P P P ++ SG T
Sbjct: 70 QSKEPAESAAVAHERPPGGTGSADPERPP---GATCPESPGPGPPHPLGVVESGKGPPPT 126
Query: 375 EGLGTVRPEQDPAKSPGSPLL 395
E++ + PG P L
Sbjct: 127 -------TEEEASGPPGEPRL 140
Score = 33.5 bits (75), Expect = 0.64
Identities = 109/431 (25%), Positives = 148/431 (34%), Gaps = 85/431 (19%)
Query: 200 GSGTEPPASTAALRTTPSPPSPGP----------ETPPAGVPPAASSQVWAAGP---AAQ 246
G EP A + L P+PP+P P +PP +PP A + A GP A++
Sbjct: 1211 GPVREPTAPESELEGQPTPPAPPPLPETWTPTARSSPP--LPPPAEERTSAKGPETMASK 1268
Query: 247 EWLSRDLLHRPSDALAKKGLGPFLQTAKPA---RRGQTSASILPRVVQAQRGPQPPPGEA 303
S P L +G P + PA G +S S R G P EA
Sbjct: 1269 FPSSSSDWRVPGQGLENRGEPPTPPSPAPAPAVAPGGSSESSSGRAA----GDTPERKEA 1324
Query: 304 GIPGHPTPPATLPSEPVEGVQASPWRPRPVLPTHPALTLPVSSDASSPSPPAPRPE-RPE 362
G RP P+ T ++ V S+ A PE RPE
Sbjct: 1325 AGTGKKVKV----------------RPPPLKKTFDSVDNRVLSEVDFEERFAELPEFRPE 1368
Query: 363 SLLVSGPSVTLTEGLGTVRPEQDPAKSPGSPLLLRGLSSGDVAAPE----PIMGEPGQAS 418
+L PS TL + L T P GS R S+ +APE P ++S
Sbjct: 1369 EVL---PSPTL-QSLAT-----SPRAILGSYRKKRKNSTDLDSAPEDPTSPKRKMRRRSS 1419
Query: 419 EEFQPLARPWRATLAAEELVSHRSPGEPQETCSGTEVERPRQTGPGLPREGARGHMDLSS 478
+P P A + R+ E ++ E ++ +P R +D
Sbjct: 1420 CSSEP-NTPKSAKCEGDIFTFDRTGTEAEDVLGELEYDK-------VPYSSLRRTLDQRR 1471
Query: 479 SEPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMPRVRLAAPLAVLPME 538
+ Q + G P+ AT + R D + S + VR A P E
Sbjct: 1472 ALVMQLFQDHG--FFPSAQAT-AAFQARYAD--IFPSKVCLQLKIREVRQKIMQAATPTE 1526
Query: 539 -------PLP-PEPVRPAALLTPEASSVGGPD------QARYLESAPGWP------VGQE 578
PLP P P AA P S GGPD + ++AP P GQ
Sbjct: 1527 QPPGAEAPLPVPPPTGTAAAPAPTPSPAGGPDPTSPSSDSGTAQAAPPLPPPPESGPGQP 1586
Query: 579 EWGVAHTSSPP 589
W A SPP
Sbjct: 1587 GWEGAPQPSPP 1597
Score = 30.4 bits (67), Expect = 5.4
Identities = 36/124 (29%), Positives = 45/124 (36%), Gaps = 20/124 (16%)
Query: 480 EPSQDIEGPGLSILPARDATFSTPSVRQPDPSAWLSSGPELTGMP----RVRLAAPLAVL 535
EP P S++P F PS QPDPS S + P + + A A +
Sbjct: 28 EPRSVAVFPWHSLVP-----FLAPS--QPDPSVQPSEAQQPASHPVASNQSKEPAESAAV 80
Query: 536 PMEPLP-----PEPVRPAALLTPEASSVGGPDQARYLESAPGWPVGQEEWGVAHTSSPPS 590
E P +P RP PE+ G P +ES G P EE S PP
Sbjct: 81 AHERPPGGTGSADPERPPGATCPESPGPGPPHPLGVVESGKGPPPTTEE----EASGPPG 136
Query: 591 TQTL 594
L
Sbjct: 137 EPRL 140
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.312 0.131 0.398
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 33,849,047
Number of Sequences: 37866
Number of extensions: 2175755
Number of successful extensions: 25409
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 238
Number of HSP's successfully gapped in prelim test: 1562
Number of HSP's that attempted gapping in prelim test: 12205
Number of HSP's gapped (non-prelim): 8672
length of query: 656
length of database: 18,247,518
effective HSP length: 109
effective length of query: 547
effective length of database: 14,120,124
effective search space: 7723707828
effective search space used: 7723707828
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.