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Search of human proteins with 27734905
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|27734905 aprataxin and PNKP like factor [Homo sapiens]
(511 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|27734905 aprataxin and PNKP like factor [Homo sapiens] 1045 0.0
gi|117676384 splicing factor, arginine/serine-rich 2, interactin... 42 0.001
gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens] 40 0.005
gi|87299628 biorientation of chromosomes in cell division 1-like... 40 0.005
gi|109638751 ubiquitin specific protease 6 [Homo sapiens] 40 0.005
gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homo... 40 0.005
gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens] 40 0.007
gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens] 40 0.007
gi|153791492 eukaryotic translation initiation factor 3, subunit... 39 0.009
gi|60498973 myelin transcription factor 1-like [Homo sapiens] 39 0.009
gi|83700233 eukaryotic translation initiation factor 3, subunit ... 39 0.009
gi|4503525 eukaryotic translation initiation factor 3, subunit C... 39 0.009
gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)... 39 0.015
gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens] 39 0.015
gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens] 39 0.015
gi|68299795 chromodomain helicase DNA binding protein 1 [Homo sa... 38 0.019
gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1 precu... 37 0.033
gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2 pre... 37 0.033
gi|40254947 thioredoxin-related transmembrane protein 4 [Homo sa... 37 0.033
gi|55956788 nucleolin [Homo sapiens] 37 0.043
gi|239752832 PREDICTED: similar to SET translocation [Homo sapiens] 37 0.043
gi|239747380 PREDICTED: similar to SET translocation [Homo sapiens] 37 0.043
gi|239741205 PREDICTED: similar to SET translocation [Homo sapiens] 37 0.043
gi|170763500 SET translocation (myeloid leukemia-associated) iso... 37 0.043
gi|170763498 SET translocation (myeloid leukemia-associated) iso... 37 0.043
gi|50511945 cajalin 2 isoform a [Homo sapiens] 37 0.043
gi|7662238 apoptotic chromatin condensation inducer 1 [Homo sapi... 37 0.056
gi|22035548 amyloid beta A4 precursor protein-binding, family A,... 37 0.056
gi|23957698 luman-recruiting factor [Homo sapiens] 37 0.056
gi|21327708 nucleosome assembly protein 1-like 1 [Homo sapiens] 36 0.073
>gi|27734905 aprataxin and PNKP like factor [Homo sapiens]
Length = 511
Score = 1045 bits (2701), Expect = 0.0
Identities = 511/511 (100%), Positives = 511/511 (100%)
Query: 1 MSGGFELQPRDGGPRVALAPGETVIGRGPLLGITDKRVSRRHAILEVAGGQLRIKPIHTN 60
MSGGFELQPRDGGPRVALAPGETVIGRGPLLGITDKRVSRRHAILEVAGGQLRIKPIHTN
Sbjct: 1 MSGGFELQPRDGGPRVALAPGETVIGRGPLLGITDKRVSRRHAILEVAGGQLRIKPIHTN 60
Query: 61 PCFYQSSEKSQLLPLKPNLWCYLNPGDSFSLLVDKYIFRILSIPSEVEMQCTLRNSQVLD 120
PCFYQSSEKSQLLPLKPNLWCYLNPGDSFSLLVDKYIFRILSIPSEVEMQCTLRNSQVLD
Sbjct: 61 PCFYQSSEKSQLLPLKPNLWCYLNPGDSFSLLVDKYIFRILSIPSEVEMQCTLRNSQVLD 120
Query: 121 EDNILNETPKSPVINLPHETTGASQLEGSTEIAKTQMTPTNSVSFLGENRDCNKQQPILA 180
EDNILNETPKSPVINLPHETTGASQLEGSTEIAKTQMTPTNSVSFLGENRDCNKQQPILA
Sbjct: 121 EDNILNETPKSPVINLPHETTGASQLEGSTEIAKTQMTPTNSVSFLGENRDCNKQQPILA 180
Query: 181 ERKRILPTWMLAEHLSDQNLSVPAISGGNVIQGSGKEEICKDKSQLNTTQQGRRQLISSG 240
ERKRILPTWMLAEHLSDQNLSVPAISGGNVIQGSGKEEICKDKSQLNTTQQGRRQLISSG
Sbjct: 181 ERKRILPTWMLAEHLSDQNLSVPAISGGNVIQGSGKEEICKDKSQLNTTQQGRRQLISSG 240
Query: 241 SSENTSAEQDTGEECKNTDQEESTISSKEMPQSFSAITLSNTEMNNIKTNAQRNKLPIEE 300
SSENTSAEQDTGEECKNTDQEESTISSKEMPQSFSAITLSNTEMNNIKTNAQRNKLPIEE
Sbjct: 241 SSENTSAEQDTGEECKNTDQEESTISSKEMPQSFSAITLSNTEMNNIKTNAQRNKLPIEE 300
Query: 301 LGKVSKHKIATKRTPHKEDEAMSCSENCSSAQGDSLQDESQGSHSESSSNPSNPETLHAK 360
LGKVSKHKIATKRTPHKEDEAMSCSENCSSAQGDSLQDESQGSHSESSSNPSNPETLHAK
Sbjct: 301 LGKVSKHKIATKRTPHKEDEAMSCSENCSSAQGDSLQDESQGSHSESSSNPSNPETLHAK 360
Query: 361 ATDSVLQGSEGNKVKRTSCMYGANCYRKNPVHFQHFSHPGDSDYGGVQIVGQDETDDRPE 420
ATDSVLQGSEGNKVKRTSCMYGANCYRKNPVHFQHFSHPGDSDYGGVQIVGQDETDDRPE
Sbjct: 361 ATDSVLQGSEGNKVKRTSCMYGANCYRKNPVHFQHFSHPGDSDYGGVQIVGQDETDDRPE 420
Query: 421 CPYGPSCYRKNPQHKIEYRHNTLPVRNVLDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTD 480
CPYGPSCYRKNPQHKIEYRHNTLPVRNVLDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTD
Sbjct: 421 CPYGPSCYRKNPQHKIEYRHNTLPVRNVLDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTD 480
Query: 481 EDSDWEPGKEDEEKEDVEELLKEAKRFMKRK 511
EDSDWEPGKEDEEKEDVEELLKEAKRFMKRK
Sbjct: 481 EDSDWEPGKEDEEKEDVEELLKEAKRFMKRK 511
>gi|117676384 splicing factor, arginine/serine-rich 2, interacting
protein [Homo sapiens]
Length = 1463
Score = 42.4 bits (98), Expect = 0.001
Identities = 73/387 (18%), Positives = 138/387 (35%), Gaps = 31/387 (8%)
Query: 120 DEDNILNETPKSPVINLPHETTGASQLEGSTEIAKTQMTPTNSVSFLGENRDCNKQQPIL 179
+++ L E P+S + H Q++ +M P SF + + + +
Sbjct: 683 EKNESLTEHPRSTELPKTH----IEQIQKHFSEDNNEMIPMECDSFCSDQNESEVEPSVN 738
Query: 180 AERKRILPTWMLAEHLSDQNLSVPAISGGNVIQGSGKEEICKDKSQLNTTQQGRRQLISS 239
A+ K++ + H S+ N+ ++ V S E KD + RR S
Sbjct: 739 ADLKQMNENSVT--HCSENNMPSSDLADEKVETVSQPSESPKDTIDKTKKPRTRRSRFHS 796
Query: 240 GSSENTSAEQDTGEECKNTDQEESTISS-KEMPQSFSAITLSNTEMNNIKTNAQRNKLPI 298
S+ S +DT +E K + KE +S S + + K+ +Q K I
Sbjct: 797 PST-TWSPNKDTPQEKKRPQSPSPRRETGKESRKSQSPSPKNESARGRKKSRSQSPKKDI 855
Query: 299 EELGKVSKHKIATKRTPHKEDEAMSCSENCSSAQGDSLQDESQGSHSESSSNPSNPETLH 358
+ S+ R+P ++ S S + ++ ++ + S+P
Sbjct: 856 ARERRQSQ-----SRSPKRDTTRESRRSESLSPRRETSRENKRSQPRVKDSSPGEKSRSQ 910
Query: 359 AKATDSVLQGSEGNKVKRTSCMYGANCYRKNPVHFQHFSHPGDSDYGGVQIVGQDE---- 414
++ +S G + +RT + + ++P + S S +G +
Sbjct: 911 SRERESDRDGQRRERERRTRKWSRSRSHSRSPSRCRTKSK--SSSFGRIDRDSYSPRWKG 968
Query: 415 --TDDRPECPYGPSCYRKNPQHKIEYRHNTLPVRN--VLDEDNDNVGQPNEYDLNDSFLD 470
+D CP G YRKN K NT +N LD D+ N + D + +
Sbjct: 969 RWANDGWRCPRGNDRYRKNDPEK--QNENTRKEKNDIHLDADDPNSADKHRNDCPNWITE 1026
Query: 471 DEEEDYEPTD------EDSDWEPGKED 491
+P ++S WE + +
Sbjct: 1027 KINSGPDPRTRNPEKLKESHWEENRNE 1053
>gi|89001107 dentin sialophosphoprotein preproprotein [Homo sapiens]
Length = 1301
Score = 40.0 bits (92), Expect = 0.005
Identities = 53/289 (18%), Positives = 102/289 (35%), Gaps = 19/289 (6%)
Query: 213 GSGKEEIC-KDKSQLNTTQQGRRQLISSGSSENTSAEQDTGE----ECKNTDQEESTISS 267
G GK + D S + + S S N+S++ D+ + + ++D +S+ SS
Sbjct: 543 GKGKSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSDSSDSDSSDSSNSS 602
Query: 268 KEMPQSFSAITLSNTEMNNIKTNAQRNKLPIEELGKVSKHKIATKRTPHKEDEAMSCSEN 327
S S+ + +++ ++ K+++ +++ + SK + + D + S +
Sbjct: 603 DSSDSSDSSDSSDSSDSSDSKSDSSKSE--SDSSDSDSKSDSSDSNSSDSSDNSDSSDSS 660
Query: 328 CSSAQGDSLQDESQGSHSESSSNPSNPETLHAKATDSVLQGSEGNKVKRTSCMYGANCYR 387
SS DS D S S S SSS+ SN + S S + S ++
Sbjct: 661 NSSNSSDS-SDSSDSSDSSSSSDSSNSSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSS 719
Query: 388 KNPVHFQHFSHPGDSDYGGVQIVGQDETDDRPECPYGPSCYRKNPQHKIEYRHNTLPVRN 447
+ S+ DS D +D S N +
Sbjct: 720 NSNSSDSDSSNSSDSSDSSNSSDSSDSSDSSNSSDSSDSSDSSNSSDSSD---------- 769
Query: 448 VLDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKED 496
+ +D+ N D NDS + D + + S+ + + D
Sbjct: 770 -SSDSSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSD 817
Score = 35.4 bits (80), Expect = 0.12
Identities = 29/134 (21%), Positives = 56/134 (41%), Gaps = 12/134 (8%)
Query: 239 SGSSENTSAEQDTGEECKNTDQEESTISSKEMPQSFSAITLSNTEMNNIKTNAQRNKLPI 298
S S N+S D+ + ++D +S+ SS S S+ + +++ ++ ++ +
Sbjct: 1174 SSDSSNSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSD--- 1230
Query: 299 EELGKVSKHKIATKRTPHKEDEAMSCSENCSSAQGDSLQDESQGSHSESSSNPSNPETLH 358
S + + D + S + SS DS D + S S+S S N +
Sbjct: 1231 ------SNESSDSSDSSDSSDSSNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGNN---N 1281
Query: 359 AKATDSVLQGSEGN 372
+DS +GS+ N
Sbjct: 1282 GSDSDSDSEGSDSN 1295
Score = 34.7 bits (78), Expect = 0.21
Identities = 32/169 (18%), Positives = 70/169 (41%), Gaps = 6/169 (3%)
Query: 196 SDQNLSVPAISGGNVIQGSGKEEICKDKSQLNTTQQGRRQLISSGSSENTSAEQDTGEEC 255
SD N S + S + S + D S + + SS SS+++ ++ D+ +
Sbjct: 572 SDSNSSSDSDSSDSDSSDSSDSD-SSDSSNSSDSSDSSDSSDSSDSSDSSDSKSDSSKSE 630
Query: 256 KNTDQEESTISSKEMPQSFSAITLSNTEMNNIKTNAQRNKLPIEELGKVSKHKIATKRTP 315
++ +S S + S S+ +++ +N ++ + + S ++ +
Sbjct: 631 SDSSDSDSKSDSSDSNSSDSSDNSDSSDSSNSSNSSDSS-----DSSDSSDSSSSSDSSN 685
Query: 316 HKEDEAMSCSENCSSAQGDSLQDESQGSHSESSSNPSNPETLHAKATDS 364
+ S S N S + S +S S S SSN ++ ++ + ++DS
Sbjct: 686 SSDSSDSSDSSNSSESSDSSDSSDSDSSDSSDSSNSNSSDSDSSNSSDS 734
Score = 34.3 bits (77), Expect = 0.28
Identities = 33/153 (21%), Positives = 62/153 (40%), Gaps = 3/153 (1%)
Query: 222 DKSQLNTTQQGRRQLISSGSSENTSAEQDTGEECKNTDQEESTISSKEMPQSFSAITLSN 281
D S + + SS SSE++ + D+ + ++D +S+ SS S S+ + +
Sbjct: 1128 DSSDSSDSSDSSNSSDSSDSSESSDSS-DSSDSSDSSDSSDSSDSSDSSDSSNSSDSSDS 1186
Query: 282 TEMNNIKTNAQRNKLPIEELGKVSKHKIATKRTPHKEDEAMSCSENCSSAQGDSLQ--DE 339
++ ++ ++ + S + + D + S N SS DS D
Sbjct: 1187 SDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSSDSNESSDSSDSSDSSDS 1246
Query: 340 SQGSHSESSSNPSNPETLHAKATDSVLQGSEGN 372
S S S SS+ S+ + +DS + GN
Sbjct: 1247 SNSSDSSDSSDSSDSTSDSNDESDSQSKSGNGN 1279
Score = 32.7 bits (73), Expect = 0.81
Identities = 23/133 (17%), Positives = 60/133 (45%), Gaps = 7/133 (5%)
Query: 239 SGSSENTSAEQDTGEECKNTDQEESTISSKEMPQSFSAITLSNTEMNNIKTNAQRNKLPI 298
S S ++S D+ + ++D +S+ SS S S+ + +++ ++ ++ N
Sbjct: 773 SSDSSDSSNSSDSNDSSNSSDSSDSSNSSDSSNSSDSSDSSDSSDSDSSNSSDSSNSSDS 832
Query: 299 EELGKVSKHKIATKRTPHKEDEAMSCSENCSSAQGDSLQDESQGSHS-------ESSSNP 351
+ S ++ + + ++ + S++ +S+ D S S S ESS++
Sbjct: 833 SDSSNSSDSSDSSDSSDGSDSDSSNRSDSSNSSDSSDSSDSSNSSDSSDSSDSNESSNSS 892
Query: 352 SNPETLHAKATDS 364
+ ++ ++ +DS
Sbjct: 893 DSSDSSNSSDSDS 905
Score = 30.8 bits (68), Expect = 3.1
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 6/60 (10%)
Query: 319 DEAMSCSENCSSAQGDSL------QDESQGSHSESSSNPSNPETLHAKATDSVLQGSEGN 372
D+A S S+N SS++GD+ +D GS S+ + + + T +DS G+ GN
Sbjct: 475 DDANSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNNGN 534
Score = 29.6 bits (65), Expect = 6.8
Identities = 26/124 (20%), Positives = 54/124 (43%), Gaps = 8/124 (6%)
Query: 241 SSENTSAEQDTGEECKNTDQEESTISSKEMPQSFSAITLSNTEMNNIKTNAQRNKLPIEE 300
+SE+ + G+ N+D+ + + + + + S ++ NN +N N
Sbjct: 478 NSESDNNSSSRGDASYNSDESKDNGNGSDSKGAEDDDSDSTSDTNNSDSNGNGNN----- 532
Query: 301 LGKVSKHKIATKRTPHKEDEAMSCSENCSSAQGDSLQDESQGSHSESSSNPSNPETLHAK 360
G K + + K D + S S + S++ S +S S S SSS+ + ++ +
Sbjct: 533 -GNDDNDKSDSGKG--KSDSSDSDSSDSSNSSDSSDSSDSDSSDSNSSSDSDSSDSDSSD 589
Query: 361 ATDS 364
++DS
Sbjct: 590 SSDS 593
>gi|87299628 biorientation of chromosomes in cell division 1-like
[Homo sapiens]
Length = 3051
Score = 40.0 bits (92), Expect = 0.005
Identities = 41/168 (24%), Positives = 70/168 (41%), Gaps = 24/168 (14%)
Query: 229 TQQGRRQLISSGSSENTSAEQDTGE--ECKNTDQEESTISSKEMPQSFSAITLSNTEMNN 286
T + RRQ I+ E Q E E K + E T SSK Q S++ L + +
Sbjct: 489 TVEQRRQSIAKEKEERLLRRQINREKLEEKRKQKAEKTKSSKTKGQGRSSVDLEESSTKS 548
Query: 287 IKTNAQRNKLPIEELGKVSKHKIAT----------------KRTPHKED--EAMSCSENC 328
++ A R K ++E KV + K+A K+ ++ED E + SE+C
Sbjct: 549 LEPKAARIKEVLKER-KVLEKKVALSKKRKKDSRNVEENSKKKQQYEEDSKETLKTSEHC 607
Query: 329 SSAQGDSLQDESQGSHSESSSNPSNPETLHAKATDSVLQGSEGNKVKR 376
+ + + H + S PS P +++ V + +K++R
Sbjct: 608 EK---EKISSSKELKHVHAKSEPSKPARRLSESLHVVDENKNESKLER 652
>gi|109638751 ubiquitin specific protease 6 [Homo sapiens]
Length = 1406
Score = 40.0 bits (92), Expect = 0.005
Identities = 46/221 (20%), Positives = 85/221 (38%), Gaps = 31/221 (14%)
Query: 163 VSFLGENRDCNK----QQPILAERKRILPTWMLAEHLSDQNLSVPAISGGNVIQGSGKEE 218
V FL E+ D + + P L + K + P + LS + + + +GKE+
Sbjct: 1097 VRFLRESFDPSAFLVPRDPALCQHKPLTPQ---GDELSKPRILAREVKKVDAQSSAGKED 1153
Query: 219 ICKDKSQLNTTQQGRRQLISSGSSENTSAEQDTGEECKNTDQEESTISSKEMPQSFSAIT 278
+ KS + + ISS + S+ + +G C ++ S + + +S +
Sbjct: 1154 MLLSKSPSSLSAN-----ISSSPKGSPSSSRKSGTSCPSSKNSSPNSSPRTLGRSKGRLR 1208
Query: 279 LSNTEMNNIKTNAQRNKLPIEE--LGKVSKHKIATKR------------TPHKEDEAMSC 324
L N +++++N +E G++ + A R TP + A++
Sbjct: 1209 LPQIGSKNKPSSSKKNLDASKENGAGQICELADALSRGHMRGGSQPELVTPQDHEVALAN 1268
Query: 325 S-----ENCSSAQGDSLQDESQGSHSESSSNPSNPETLHAK 360
E C + GD + G+HSE S E H K
Sbjct: 1269 GFLYEHEACGNGCGDGYSNGQLGNHSEEDSTDDQREDTHIK 1309
>gi|20270337 Leo1, Paf1/RNA polymerase II complex component, homolog
[Homo sapiens]
Length = 666
Score = 40.0 bits (92), Expect = 0.005
Identities = 61/313 (19%), Positives = 116/313 (37%), Gaps = 31/313 (9%)
Query: 209 NVIQGSGKEEICKDKSQLNTTQQGRRQLISSGSSENTSAEQDTGEECKNTDQEESTISS- 267
+V Q SG E D+ + + + G + GS + S ++ G E K+ ++ I +
Sbjct: 103 DVDQHSGSEAPNDDEDEGHRSDGGSHHSEAEGSEKAHSDDEKWGREDKSDQSDDEKIQNS 162
Query: 268 --KEMPQSFSAITLSNTEMNNIKTNAQRNKLPIEELGKVSKHKIATKRTPHKEDEAMSCS 325
+E Q L N++ + N + P +L + +++ + + +DE S
Sbjct: 163 DDEERAQGSDEDKLQNSDDDEKMQNTDDEERP--QLSDDERQQLSEEEKANSDDERPVAS 220
Query: 326 ENCSSAQGDSLQDESQGSHSESSSN-----PSNPETLHAKATDSVLQGSEGNKVKRTSC- 379
+N Q +++ Q S E N P + H + D Q + + +
Sbjct: 221 DNDDEKQNSDDEEQPQLSDEEKMQNSDDERPQASDEEHRHSDDEEEQDHKSESARGSDSE 280
Query: 380 -----MYGANCYRKNPVHFQHFSHPGDSD-----YGGV-QIVGQDETDDRPECPYGPSCY 428
M N + P D+ +GG I + +D+P P P
Sbjct: 281 DEVLRMKRKNAIASDSEADSDTEVPKDNSGTMDLFGGADDISSGSDGEDKPPTPGQPVDE 340
Query: 429 RKNPQHKIEYRHNTLPVRNV---LDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDW 485
PQ + E +P + + + N ++G + +FL E ++P + ++
Sbjct: 341 NGLPQDQQE--EEPIPETRIEVEIPKVNTDLGNDLYFVKLPNFLSVEPRPFDPQYYEDEF 398
Query: 486 EPGKEDEEKEDVE 498
EDEE D E
Sbjct: 399 ----EDEEMLDEE 407
>gi|253970456 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 39.7 bits (91), Expect = 0.007
Identities = 67/329 (20%), Positives = 111/329 (33%), Gaps = 41/329 (12%)
Query: 192 AEHLSDQNLSVPAISGGNVIQGSGKEEICKDKSQLNTTQQGRRQLISSGSSEN----TSA 247
A H S+ S ++ G EE +K T G G+SEN +S
Sbjct: 399 ARHFSEHP-STSKMNAQETATGMAFEEPIDEKKFEKTEDGGE---FEEGASENNAKESSP 454
Query: 248 EQDTGEECKNTDQEES--------TISSKEMPQ------SFSAITLSNTEMNNIKTNAQR 293
E++ E C + EE + S KE + S ++ +K + +
Sbjct: 455 EKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEE 514
Query: 294 NKLPIE---ELGKVSKHKIATKRTPHKEDEAMSCSENCSSAQ---GDSLQDESQGSHSES 347
N L E +L K S+ ++ + ++D E+CS Q G + E G +
Sbjct: 515 NGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDL 574
Query: 348 SSNPSNPETLHAKATDSVLQGSEG-NKVKRTSCMYGANCYRKNPVHFQHFSHPGDSDYGG 406
S E LH D L+ ++ N + F S + +
Sbjct: 575 DEEGSEKE-LHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDT 633
Query: 407 VQIVGQDETDDRPECPYGPSCYRKNPQHKIEYRHNTLPVRNVLDEDNDNVGQPNEY---- 462
+ V DE+D++ + Y + K E + D+ D E
Sbjct: 634 YEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDAD 693
Query: 463 -------DLNDSFLDDEEEDYEPTDEDSD 484
D N+ D+EE+ E +DSD
Sbjct: 694 EKLFEDDDSNEKLFDEEEDSSEKLFDDSD 722
Score = 35.0 bits (79), Expect = 0.16
Identities = 52/206 (25%), Positives = 81/206 (39%), Gaps = 34/206 (16%)
Query: 305 SKHKIATKRTPHKEDEAMSCSENCSSA--QGDSLQDESQ------GSHSESSSNPSNPET 356
S K A + P KE E E C +G Q ES+ GS +S S +T
Sbjct: 453 SPEKEAEEGCPEKESE-----EGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKT 507
Query: 357 LHAKATDSVLQGSEGNKVKRTSCMYGANCYRKNPVHFQHFSHPGDSDYGGVQIVGQDETD 416
L ++ L + + + S + V S DS+ + + +++
Sbjct: 508 LKNDCEENGLAKESEDDLNKES---------EEEVGPTKESEEDDSEKESDEDCSEKQSE 558
Query: 417 DRPECPYGPSCYRKNPQHKIEYRHNTLPVRNVLD---EDNDNVGQPNEYDLNDSFLDDEE 473
D E + + K+ + + NVLD E+ND+ E D ++ LD+E
Sbjct: 559 DGSEREFEENGLEKDLDEEGSEKELH---ENVLDKELEENDSENSEFEDDGSEKVLDEEG 615
Query: 474 EDYEPTDEDSDWEPGKEDEEKEDVEE 499
+ E DEDSD E EE+ED E
Sbjct: 616 SERE-FDEDSD-----EKEEEEDTYE 635
Score = 30.4 bits (67), Expect = 4.0
Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 6/53 (11%)
Query: 448 VLDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKEDVEEL 500
VLDE+ G E+D + ++EE+ YE +D E KEDEE D + L
Sbjct: 610 VLDEE----GSEREFDEDSDEKEEEEDTYEKVFDDESDE--KEDEEYADEKGL 656
>gi|21361437 HIV-1 Tat specific factor 1 [Homo sapiens]
Length = 755
Score = 39.7 bits (91), Expect = 0.007
Identities = 67/329 (20%), Positives = 111/329 (33%), Gaps = 41/329 (12%)
Query: 192 AEHLSDQNLSVPAISGGNVIQGSGKEEICKDKSQLNTTQQGRRQLISSGSSEN----TSA 247
A H S+ S ++ G EE +K T G G+SEN +S
Sbjct: 399 ARHFSEHP-STSKMNAQETATGMAFEEPIDEKKFEKTEDGGE---FEEGASENNAKESSP 454
Query: 248 EQDTGEECKNTDQEES--------TISSKEMPQ------SFSAITLSNTEMNNIKTNAQR 293
E++ E C + EE + S KE + S ++ +K + +
Sbjct: 455 EKEAEEGCPEKESEEGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKTLKNDCEE 514
Query: 294 NKLPIE---ELGKVSKHKIATKRTPHKEDEAMSCSENCSSAQ---GDSLQDESQGSHSES 347
N L E +L K S+ ++ + ++D E+CS Q G + E G +
Sbjct: 515 NGLAKESEDDLNKESEEEVGPTKESEEDDSEKESDEDCSEKQSEDGSEREFEENGLEKDL 574
Query: 348 SSNPSNPETLHAKATDSVLQGSEG-NKVKRTSCMYGANCYRKNPVHFQHFSHPGDSDYGG 406
S E LH D L+ ++ N + F S + +
Sbjct: 575 DEEGSEKE-LHENVLDKELEENDSENSEFEDDGSEKVLDEEGSEREFDEDSDEKEEEEDT 633
Query: 407 VQIVGQDETDDRPECPYGPSCYRKNPQHKIEYRHNTLPVRNVLDEDNDNVGQPNEY---- 462
+ V DE+D++ + Y + K E + D+ D E
Sbjct: 634 YEKVFDDESDEKEDEEYADEKGLEAADKKAEEGDADEKLFEESDDKEDEDADGKEVEDAD 693
Query: 463 -------DLNDSFLDDEEEDYEPTDEDSD 484
D N+ D+EE+ E +DSD
Sbjct: 694 EKLFEDDDSNEKLFDEEEDSSEKLFDDSD 722
Score = 35.0 bits (79), Expect = 0.16
Identities = 52/206 (25%), Positives = 81/206 (39%), Gaps = 34/206 (16%)
Query: 305 SKHKIATKRTPHKEDEAMSCSENCSSA--QGDSLQDESQ------GSHSESSSNPSNPET 356
S K A + P KE E E C +G Q ES+ GS +S S +T
Sbjct: 453 SPEKEAEEGCPEKESE-----EGCPKRGFEGSCSQKESEEGNPVRGSEEDSPKKESKKKT 507
Query: 357 LHAKATDSVLQGSEGNKVKRTSCMYGANCYRKNPVHFQHFSHPGDSDYGGVQIVGQDETD 416
L ++ L + + + S + V S DS+ + + +++
Sbjct: 508 LKNDCEENGLAKESEDDLNKES---------EEEVGPTKESEEDDSEKESDEDCSEKQSE 558
Query: 417 DRPECPYGPSCYRKNPQHKIEYRHNTLPVRNVLD---EDNDNVGQPNEYDLNDSFLDDEE 473
D E + + K+ + + NVLD E+ND+ E D ++ LD+E
Sbjct: 559 DGSEREFEENGLEKDLDEEGSEKELH---ENVLDKELEENDSENSEFEDDGSEKVLDEEG 615
Query: 474 EDYEPTDEDSDWEPGKEDEEKEDVEE 499
+ E DEDSD E EE+ED E
Sbjct: 616 SERE-FDEDSD-----EKEEEEDTYE 635
Score = 30.4 bits (67), Expect = 4.0
Identities = 20/53 (37%), Positives = 28/53 (52%), Gaps = 6/53 (11%)
Query: 448 VLDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKEDVEEL 500
VLDE+ G E+D + ++EE+ YE +D E KEDEE D + L
Sbjct: 610 VLDEE----GSEREFDEDSDEKEEEEDTYEKVFDDESDE--KEDEEYADEKGL 656
>gi|153791492 eukaryotic translation initiation factor 3, subunit
C-like [Homo sapiens]
Length = 914
Score = 39.3 bits (90), Expect = 0.009
Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 3/45 (6%)
Query: 469 LDDEEEDYEPTDEDSDWEPGKEDEEKEDVEELLKE---AKRFMKR 510
+DDE+ED E +++D DW+ G + + EE K+ A RF+K+
Sbjct: 215 MDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKK 259
>gi|60498973 myelin transcription factor 1-like [Homo sapiens]
Length = 1184
Score = 39.3 bits (90), Expect = 0.009
Identities = 19/49 (38%), Positives = 29/49 (59%)
Query: 451 EDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKEDVEE 499
EDND G +E D ++EE + E D+D D E +++EE+E+ EE
Sbjct: 112 EDNDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEE 160
Score = 33.9 bits (76), Expect = 0.36
Identities = 14/50 (28%), Positives = 31/50 (62%)
Query: 450 DEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKEDVEE 499
DE+++ + E ++ + DD+E+ + DE+ + E +E+EE+E+ E+
Sbjct: 121 DEEDEEGDREEEEEIEEEDEDDDEDGEDVEDEEEEEEEEEEEEEEEENED 170
Score = 33.5 bits (75), Expect = 0.47
Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 1/45 (2%)
Query: 452 DNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKED 496
D+ +V + ++ D + + EE++ E ED+D EPG EDEE E+
Sbjct: 83 DSSSVDECDDSDGTEDMDEKEEDEGEEYSEDND-EPGDEDEEDEE 126
Score = 31.2 bits (69), Expect = 2.3
Identities = 19/54 (35%), Positives = 31/54 (57%), Gaps = 4/54 (7%)
Query: 449 LDEDNDNVGQPNEYDLNDSFLDDEEEDYE---PTDEDSDWEPGKEDEEKEDVEE 499
+DE ++ G+ D ND D++EED E +E+ + E +DE+ EDVE+
Sbjct: 99 MDEKEEDEGEEYSED-NDEPGDEDEEDEEGDREEEEEIEEEDEDDDEDGEDVED 151
>gi|83700233 eukaryotic translation initiation factor 3, subunit C
[Homo sapiens]
Length = 913
Score = 39.3 bits (90), Expect = 0.009
Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 3/45 (6%)
Query: 469 LDDEEEDYEPTDEDSDWEPGKEDEEKEDVEELLKE---AKRFMKR 510
+DDE+ED E +++D DW+ G + + EE K+ A RF+K+
Sbjct: 215 MDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKK 259
>gi|4503525 eukaryotic translation initiation factor 3, subunit C
[Homo sapiens]
Length = 913
Score = 39.3 bits (90), Expect = 0.009
Identities = 17/45 (37%), Positives = 28/45 (62%), Gaps = 3/45 (6%)
Query: 469 LDDEEEDYEPTDEDSDWEPGKEDEEKEDVEELLKE---AKRFMKR 510
+DDE+ED E +++D DW+ G + + EE K+ A RF+K+
Sbjct: 215 MDDEDEDSEDSEDDEDWDTGSTSSDSDSEEEEGKQTALASRFLKK 259
>gi|7019419 guanine nucleotide binding protein-like 2 (nucleolar)
[Homo sapiens]
Length = 731
Score = 38.5 bits (88), Expect = 0.015
Identities = 45/177 (25%), Positives = 64/177 (36%), Gaps = 18/177 (10%)
Query: 204 AISGGNVIQGSGKEEICKDKSQLNTTQQGR---------------RQLISSGSSENT--S 246
A G +++G + K LN Q+GR QL+ S S E +
Sbjct: 426 AFRTGKLLKGGEPDLQTVGKMVLNDWQRGRIPFFVKPPNAEPLVAPQLLPSSSLEVVPEA 485
Query: 247 AEQDTGEECKNTDQEESTISSKEMPQSFSAITLSNTEMNNIKTNAQRNKLPIEELGKVSK 306
A+ + GEE T E S KE + S +NTEM I T ++N I + + S
Sbjct: 486 AQNNPGEEVTETAGEGSESIIKEETEENSHCD-ANTEMQQILTRVRQNFGKINVVPQFSG 544
Query: 307 HKIATKRTPHKEDEAMSCSENCSSAQGDSLQDESQGSHSESSSNPSNPETLHAKATD 363
+ E+E S S+ Q D + S N N KA D
Sbjct: 545 DDLVPVEVSDLEEELESFSDEEEEEQEQQRDDAEESSSEPEEENVGNDTKAVIKALD 601
>gi|20336205 transcriptional regulator ATRX isoform 2 [Homo sapiens]
Length = 2454
Score = 38.5 bits (88), Expect = 0.015
Identities = 51/308 (16%), Positives = 115/308 (37%), Gaps = 27/308 (8%)
Query: 221 KDKSQLNTTQQGRRQLISSGSSENTSAEQDTGEECKNTDQEESTISSKEMPQSFSA---- 276
K S +T++ + + SS SS+ +Q++ E + +Q+ ++ + S +
Sbjct: 1147 KRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQS 1206
Query: 277 -----------ITLSNTEMNNIKTNAQRNKLPIEELGKVSKHKIATKRTPHKEDEAMSCS 325
+T+ + + +N N K+ +EE+ K +++ +DE
Sbjct: 1207 SGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEI----KANLSSDEDGSSDDEPEEGK 1262
Query: 326 ENCSSAQGDSLQDESQGSHSESSSNPSNPETLHAKATDSVLQ-------GSEGNKVKRTS 378
+ ++ DE + S S+ + E+ + +L+ G G + K
Sbjct: 1263 KRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKP 1322
Query: 379 CMYGANCYRKNPVHFQHFSHPGDSDYGGV-QIVGQDETDDRPECPYGPSCYRKNPQHKIE 437
+ R S D GV + V + E + RP + Q +
Sbjct: 1323 KEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYK 1382
Query: 438 YRHNTLPVRNVLDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKEDV 497
+ ++ D ++N E + ++EEE+ E +ED + + + ++ +
Sbjct: 1383 QKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKI 1442
Query: 498 EELLKEAK 505
++LK+ K
Sbjct: 1443 RKILKDDK 1450
Score = 32.7 bits (73), Expect = 0.81
Identities = 33/148 (22%), Positives = 57/148 (38%), Gaps = 27/148 (18%)
Query: 214 SGKEEICKDKSQLNTTQQGRRQLISSGSSENTSAEQDTGEECKNTDQEESTISSKEMPQS 273
SG+E+ K K + RR++ S S ++ E EE ++ E + P++
Sbjct: 1314 SGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDE-------QRPRT 1366
Query: 274 FSAITLSNTEMNNIKTNAQRNKLPIEELGKVSKHKIATKRTPHKEDEAMSCSENCSSAQG 333
SA K +EE + K K +R +ED S SEN S+++
Sbjct: 1367 RSA-----------------KKAELEENQRSYKQKKKRRRIKVQED---SSSENKSNSEE 1406
Query: 334 DSLQDESQGSHSESSSNPSNPETLHAKA 361
+ + E + E E +K+
Sbjct: 1407 EEEEKEEEEEEEEEEEEEEEDENDDSKS 1434
>gi|20336209 transcriptional regulator ATRX isoform 1 [Homo sapiens]
Length = 2492
Score = 38.5 bits (88), Expect = 0.015
Identities = 51/308 (16%), Positives = 115/308 (37%), Gaps = 27/308 (8%)
Query: 221 KDKSQLNTTQQGRRQLISSGSSENTSAEQDTGEECKNTDQEESTISSKEMPQSFSA---- 276
K S +T++ + + SS SS+ +Q++ E + +Q+ ++ + S +
Sbjct: 1185 KRNSLRTSTKRKQADITSSSSSDIEDDDQNSIGEGSSDEQKIKPVTENLVLSSHTGFCQS 1244
Query: 277 -----------ITLSNTEMNNIKTNAQRNKLPIEELGKVSKHKIATKRTPHKEDEAMSCS 325
+T+ + + +N N K+ +EE+ K +++ +DE
Sbjct: 1245 SGDEALSKSVPVTVDDDDDDNDPENRIAKKMLLEEI----KANLSSDEDGSSDDEPEEGK 1300
Query: 326 ENCSSAQGDSLQDESQGSHSESSSNPSNPETLHAKATDSVLQ-------GSEGNKVKRTS 378
+ ++ DE + S S+ + E+ + +L+ G G + K
Sbjct: 1301 KRTGKQNEENPGDEEAKNQVNSESDSDSEESKKPRYRHRLLRHKLTVSDGESGEEKKTKP 1360
Query: 379 CMYGANCYRKNPVHFQHFSHPGDSDYGGV-QIVGQDETDDRPECPYGPSCYRKNPQHKIE 437
+ R S D GV + V + E + RP + Q +
Sbjct: 1361 KEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDEQRPRTRSAKKAELEENQRSYK 1420
Query: 438 YRHNTLPVRNVLDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKEDV 497
+ ++ D ++N E + ++EEE+ E +ED + + + ++ +
Sbjct: 1421 QKKKRRRIKVQEDSSSENKSNSEEEEEEKEEEEEEEEEEEEEEEDENDDSKSPGKGRKKI 1480
Query: 498 EELLKEAK 505
++LK+ K
Sbjct: 1481 RKILKDDK 1488
Score = 32.7 bits (73), Expect = 0.81
Identities = 33/148 (22%), Positives = 57/148 (38%), Gaps = 27/148 (18%)
Query: 214 SGKEEICKDKSQLNTTQQGRRQLISSGSSENTSAEQDTGEECKNTDQEESTISSKEMPQS 273
SG+E+ K K + RR++ S S ++ E EE ++ E + P++
Sbjct: 1352 SGEEKKTKPKEHKEVKGRNRRKVSSEDSEDSDFQESGVSEEVSESEDE-------QRPRT 1404
Query: 274 FSAITLSNTEMNNIKTNAQRNKLPIEELGKVSKHKIATKRTPHKEDEAMSCSENCSSAQG 333
SA K +EE + K K +R +ED S SEN S+++
Sbjct: 1405 RSA-----------------KKAELEENQRSYKQKKKRRRIKVQED---SSSENKSNSEE 1444
Query: 334 DSLQDESQGSHSESSSNPSNPETLHAKA 361
+ + E + E E +K+
Sbjct: 1445 EEEEKEEEEEEEEEEEEEEEDENDDSKS 1472
>gi|68299795 chromodomain helicase DNA binding protein 1 [Homo
sapiens]
Length = 1710
Score = 38.1 bits (87), Expect = 0.019
Identities = 57/277 (20%), Positives = 109/277 (39%), Gaps = 34/277 (12%)
Query: 239 SGSSENTSAEQDTGEECKNTDQEESTISSKEMPQSFSAITLSNTEMNNIKTNAQRNKLPI 298
+G S+ S +GE ++ D S S S S+ S+++ + +++
Sbjct: 2 NGHSDEESVRNSSGESSQSDDDSGSASGSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQ 61
Query: 299 EELGKVSKHKIATKRTPHKED--EAMSCSENCSSAQGDSL-----QDESQGSHSESSSNP 351
E + + + P K D E S + + Q ++ Q + Q H SS++
Sbjct: 62 SESESDTSRENKVQAKPPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSG 121
Query: 352 SNPETLHAKATDSVLQGSEGNKVKRTSCMYGANCYRKNPVHFQHFSHPGDSDYGGVQIVG 411
S ++ ++ +D ++VKR +K+ S G G
Sbjct: 122 SEEDSSSSEDSDD-----SSSEVKR----------KKHKDEDWQMSGSGSPSQSGSDSES 166
Query: 412 QDETDDRPECPYGPSCYRKNPQHKIEYRHNTLPVRNVLDEDNDNVGQPNEYDLNDSFLDD 471
++E + + C S Y P++K++ R P ++ + + ++ S DD
Sbjct: 167 EEERE-KSSCDETESDYE--PKNKVKSRK---PQNRSKSKNGKKILGQKKRQIDSSEEDD 220
Query: 472 EEEDYEPTDEDSDWEPG-----KEDEE-KEDVEELLK 502
+EEDY+ S + KEDEE K D ++LL+
Sbjct: 221 DEEDYDNDKRSSRRQATVNVSYKEDEEMKTDSDDLLE 257
Score = 32.7 bits (73), Expect = 0.81
Identities = 47/208 (22%), Positives = 80/208 (38%), Gaps = 36/208 (17%)
Query: 318 EDEAMSCSENCSSAQGDSLQDESQGSHSESSSNPSNPETLHAKATDSVLQGSEGNKVK-R 376
+D++ S S S G S S GS S+S S+ S+ + ++S S NKV+ +
Sbjct: 21 DDDSGSAS---GSGSGSSSGSSSDGSSSQSGSSDSDSGSESGSQSESESDTSRENKVQAK 77
Query: 377 TSCMYGANCYRKNPVHF---------------QHFSHPGDSDYGGVQIVGQDETDDRPEC 421
+ GA ++ +P Q H S+ G + E D
Sbjct: 78 PPKVDGAEFWKSSPSILAVQRSAILKKQQQQQQQQQHQASSNSGSEEDSSSSEDSD---- 133
Query: 422 PYGPSCYRKNPQHKIE---YRHNTLPVRNVLDEDNDNVGQPNEYDLNDSFLDDEEEDYEP 478
S K +HK E + P ++ D ++ E + S D+ E DYEP
Sbjct: 134 --DSSSEVKRKKHKDEDWQMSGSGSPSQSGSDSES-------EEEREKSSCDETESDYEP 184
Query: 479 TDEDSDWEPGKEDEEKEDVEELLKEAKR 506
++ +P + K +++L + KR
Sbjct: 185 KNKVKSRKPQNRSKSKNG-KKILGQKKR 211
>gi|4758172 dentin matrix acidic phosphoprotein 1 isoform 1
precursor [Homo sapiens]
Length = 513
Score = 37.4 bits (85), Expect = 0.033
Identities = 44/211 (20%), Positives = 85/211 (40%), Gaps = 12/211 (5%)
Query: 197 DQNLSVPAISGGNVIQGSGKEEICKDKSQ-LNTTQQGRRQLISSGSSENTS-AEQDTGEE 254
D LS P Q KE + +++SQ ++ Q + S EN+S ++++ E
Sbjct: 303 DTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSE 362
Query: 255 CKNTDQEESTISSKEMPQSFSAITLSNTEMNNIKTNAQRNKLPIEELGKVSKHKIATKRT 314
+ + + +T ++ S S+ S+ +++ K+ ++ + E ++ + +
Sbjct: 363 SRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLN---FSEESP 419
Query: 315 PHKEDEAMSCSENCSS--AQGDSLQDESQGSHSESSSNPSNPETLHAKATDSVLQGSEGN 372
EDE S E S + +S +ES +S S S+ + +T+S E
Sbjct: 420 ESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDG 479
Query: 373 KVKRTSCMYGANCYRKNPVHFQHFSHPGDSD 403
++K RK V H GD D
Sbjct: 480 QLKNIEIE-----SRKLTVDAYHNKPIGDQD 505
>gi|121256621 dentin matrix acidic phosphoprotein 1 isoform 2
precursor [Homo sapiens]
Length = 497
Score = 37.4 bits (85), Expect = 0.033
Identities = 44/211 (20%), Positives = 85/211 (40%), Gaps = 12/211 (5%)
Query: 197 DQNLSVPAISGGNVIQGSGKEEICKDKSQ-LNTTQQGRRQLISSGSSENTS-AEQDTGEE 254
D LS P Q KE + +++SQ ++ Q + S EN+S ++++ E
Sbjct: 287 DTGLSQPRRDSKGDSQEDSKENLSQEESQNVDGPSSESSQEANLSSQENSSESQEEVVSE 346
Query: 255 CKNTDQEESTISSKEMPQSFSAITLSNTEMNNIKTNAQRNKLPIEELGKVSKHKIATKRT 314
+ + + +T ++ S S+ S+ +++ K+ ++ + E ++ + +
Sbjct: 347 SRGDNPDPTTSYVEDQEDSDSSEEDSSHTLSHSKSESREEQADSESSESLN---FSEESP 403
Query: 315 PHKEDEAMSCSENCSS--AQGDSLQDESQGSHSESSSNPSNPETLHAKATDSVLQGSEGN 372
EDE S E S + +S +ES +S S S+ + +T+S E
Sbjct: 404 ESPEDENSSSQEGLQSHSSSAESQSEESHSEEDDSDSQDSSRSKEDSNSTESKSSSEEDG 463
Query: 373 KVKRTSCMYGANCYRKNPVHFQHFSHPGDSD 403
++K RK V H GD D
Sbjct: 464 QLKNIEIE-----SRKLTVDAYHNKPIGDQD 489
>gi|40254947 thioredoxin-related transmembrane protein 4 [Homo
sapiens]
Length = 349
Score = 37.4 bits (85), Expect = 0.033
Identities = 28/89 (31%), Positives = 40/89 (44%), Gaps = 8/89 (8%)
Query: 420 ECPYGPS----CYRKNPQHKIEYRHNTLPVRNVLDEDNDNVGQPNEYDLNDSFLDDEEED 475
EC Y P R + E H +++ +E +D+ NE + DS +DDEEE
Sbjct: 212 ECFYVPLPRHLSERSEQNRRSEEAHRAEQLQDAEEEKDDS----NEEENKDSLVDDEEEK 267
Query: 476 YEPTDEDSDWEPGKEDEEKEDVEELLKEA 504
+ DED E +ED V+E EA
Sbjct: 268 EDLGDEDEAEEEEEEDNLAAGVDEERSEA 296
>gi|55956788 nucleolin [Homo sapiens]
Length = 710
Score = 37.0 bits (84), Expect = 0.043
Identities = 17/57 (29%), Positives = 35/57 (61%)
Query: 455 NVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKEDVEELLKEAKRFMKRK 511
NV + + + +D DD++++ + D+D D E +E+EE+E V+E + K+ M ++
Sbjct: 231 NVAEDEDEEEDDEDEDDDDDEDDEDDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQ 287
Score = 33.1 bits (74), Expect = 0.62
Identities = 30/101 (29%), Positives = 49/101 (48%), Gaps = 14/101 (13%)
Query: 413 DETDDRPECPYGPSCYRKNPQHKIEYRHNTLPVR--NVLDEDNDNVGQPNEYDLNDSFLD 470
DE DD E + K + +PV+ NV +++++ +E D +D D
Sbjct: 195 DEDDDDDEEDDSEEEAMETTPAKGKKAAKVVPVKAKNVAEDEDEEEDDEDEDDDDDE--D 252
Query: 471 DEEEDYEPTDEDSDWEPGKEDEEKEDVEELLKEAKRFMKRK 511
DE++D DED E+EE+E+ EE +KEA K++
Sbjct: 253 DEDDD----DEDD------EEEEEEEEEEPVKEAPGKRKKE 283
Score = 32.7 bits (73), Expect = 0.81
Identities = 19/62 (30%), Positives = 34/62 (54%), Gaps = 2/62 (3%)
Query: 450 DEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKEDVEELLKEAKRFMK 509
DE+ D+ + ++ D +D DD++ED E +E+ + EP KE K E ++A K
Sbjct: 237 DEEEDDEDEDDDDDEDDE--DDDDEDDEEEEEEEEEEPVKEAPGKRKKEMAKQKAAPEAK 294
Query: 510 RK 511
++
Sbjct: 295 KQ 296
Score = 32.3 bits (72), Expect = 1.1
Identities = 19/60 (31%), Positives = 31/60 (51%), Gaps = 12/60 (20%)
Query: 450 DEDNDNVGQPNEYDLNDSFLDDEEEDYEPT----------DEDSDWEPGKEDEEKEDVEE 499
DE+ D+ + +E D D D++E++ EP ED D E ++DE+ +D EE
Sbjct: 146 DEEEDDDSEEDEEDDEDE--DEDEDEIEPAAMKAAAAAPASEDEDDEDDEDDEDDDDDEE 203
Score = 29.3 bits (64), Expect = 8.9
Identities = 20/68 (29%), Positives = 31/68 (45%), Gaps = 13/68 (19%)
Query: 443 LPVRNVLDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSD-----------WEPGKED 491
+P + + N +E + +DS +++EED E DED D P ED
Sbjct: 129 IPAKGAKNGKNAKKEDSDEEEDDDS--EEDEEDDEDEDEDEDEIEPAAMKAAAAAPASED 186
Query: 492 EEKEDVEE 499
E+ ED E+
Sbjct: 187 EDDEDDED 194
>gi|239752832 PREDICTED: similar to SET translocation [Homo sapiens]
Length = 302
Score = 37.0 bits (84), Expect = 0.043
Identities = 20/48 (41%), Positives = 30/48 (62%), Gaps = 3/48 (6%)
Query: 450 DEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSD-WEPGKEDEEKED 496
D+D+D+ G E +L D +D+ +ED DED D E G+EDE ++D
Sbjct: 257 DDDDDDDGDEGEEELED--IDEGDEDEGEEDEDDDEGEEGEEDEGEDD 302
Score = 30.4 bits (67), Expect = 4.0
Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 441 NTLPVRNVLDEDNDNVGQPNEYDLNDSFLDDEE-EDYEPTDEDSDWEPGKEDEEKEDVEE 499
N L V D D++ G+ ++ D +D +EE ED + DED + E ++D+E E+ EE
Sbjct: 238 NPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDED-EGEEDEDDDEGEEGEE 296
>gi|239747380 PREDICTED: similar to SET translocation [Homo sapiens]
Length = 302
Score = 37.0 bits (84), Expect = 0.043
Identities = 20/48 (41%), Positives = 30/48 (62%), Gaps = 3/48 (6%)
Query: 450 DEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSD-WEPGKEDEEKED 496
D+D+D+ G E +L D +D+ +ED DED D E G+EDE ++D
Sbjct: 257 DDDDDDDGDEGEEELED--IDEGDEDEGEEDEDDDEGEEGEEDEGEDD 302
Score = 30.4 bits (67), Expect = 4.0
Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 441 NTLPVRNVLDEDNDNVGQPNEYDLNDSFLDDEE-EDYEPTDEDSDWEPGKEDEEKEDVEE 499
N L V D D++ G+ ++ D +D +EE ED + DED + E ++D+E E+ EE
Sbjct: 238 NPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDED-EGEEDEDDDEGEEGEE 296
>gi|239741205 PREDICTED: similar to SET translocation [Homo sapiens]
Length = 302
Score = 37.0 bits (84), Expect = 0.043
Identities = 20/48 (41%), Positives = 30/48 (62%), Gaps = 3/48 (6%)
Query: 450 DEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSD-WEPGKEDEEKED 496
D+D+D+ G E +L D +D+ +ED DED D E G+EDE ++D
Sbjct: 257 DDDDDDDGDEGEEELED--IDEGDEDEGEEDEDDDEGEEGEEDEGEDD 302
Score = 30.4 bits (67), Expect = 4.0
Identities = 21/60 (35%), Positives = 34/60 (56%), Gaps = 2/60 (3%)
Query: 441 NTLPVRNVLDEDNDNVGQPNEYDLNDSFLDDEE-EDYEPTDEDSDWEPGKEDEEKEDVEE 499
N L V D D++ G+ ++ D +D +EE ED + DED + E ++D+E E+ EE
Sbjct: 238 NPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDEGDED-EGEEDEDDDEGEEGEE 296
>gi|170763500 SET translocation (myeloid leukemia-associated)
isoform 1 [Homo sapiens]
Length = 290
Score = 37.0 bits (84), Expect = 0.043
Identities = 21/56 (37%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Query: 444 PVRNVLDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKEDVEE 499
P++ L D D+ E D +D D+EEE E DE+ D + G+EDE+ ++ EE
Sbjct: 229 PLQYYLVPDMDDEEGEGEEDDDD---DEEEEGLEDIDEEGDEDEGEEDEDDDEGEE 281
>gi|170763498 SET translocation (myeloid leukemia-associated)
isoform 2 [Homo sapiens]
Length = 277
Score = 37.0 bits (84), Expect = 0.043
Identities = 21/56 (37%), Positives = 32/56 (57%), Gaps = 3/56 (5%)
Query: 444 PVRNVLDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKEDVEE 499
P++ L D D+ E D +D D+EEE E DE+ D + G+EDE+ ++ EE
Sbjct: 216 PLQYYLVPDMDDEEGEGEEDDDD---DEEEEGLEDIDEEGDEDEGEEDEDDDEGEE 268
>gi|50511945 cajalin 2 isoform a [Homo sapiens]
Length = 1248
Score = 37.0 bits (84), Expect = 0.043
Identities = 32/127 (25%), Positives = 59/127 (46%), Gaps = 12/127 (9%)
Query: 190 MLAEHLSDQNLSVPAISGGNVIQGSGKEEICKDKSQLNTTQQGRRQLISSGSSENTSAEQ 249
+L EH S ++L + + ++G G+ + ++ Q + TQ+ S+ T +E
Sbjct: 265 ILKEHPSQKSLQIATLLQ-EYLEGVGRSTVLEEPVQEDATQETHISSPVESPSQKTKSET 323
Query: 250 DTGEECKNTDQEESTISSKEMPQSFSAI--TLSNTEMNNIKTNAQRNKLPIEELGKVSKH 307
TGE K D+ + +E SF + T+S+ ++N+ +K+ EELGK
Sbjct: 324 VTGELSKLLDEIK---LCQEKDYSFEDLCHTISDHYLDNL------SKISEEELGKNGSQ 374
Query: 308 KIATKRT 314
+ T T
Sbjct: 375 SVRTSST 381
>gi|7662238 apoptotic chromatin condensation inducer 1 [Homo
sapiens]
Length = 1341
Score = 36.6 bits (83), Expect = 0.056
Identities = 66/320 (20%), Positives = 112/320 (35%), Gaps = 38/320 (11%)
Query: 203 PAISGGN--VIQGSGKEEICKDKSQLNTTQQGRRQLISSGSSENTSAEQDTGEECKNTDQ 260
P SGG V+ G+ E + L T + R+L + T D K +
Sbjct: 7 PRTSGGTRGVLSGNRGVEYGSGRGHLGTFEGRWRKLPKMPEAVGT----DPSTSRKMAEL 62
Query: 261 EESTISSKEMPQSFSAITLSNTEMNNIKTNAQRNKLPIEELGKVSKHKIATKRTPHKEDE 320
EE T+ K + + E + + Q++ L G + + TPH +
Sbjct: 63 EEVTLDGKPLQALRVTDLKAALEQRGLAKSGQKSALVKRLKGALMLENLQKHSTPHAAFQ 122
Query: 321 AMS-----CSENCSSAQGDSLQDE----------SQGSHSESSSNPSNPETLHAKATDSV 365
S S+N Q Q E + + E +S S E +H + S+
Sbjct: 123 PNSQIGEEMSQNSFIKQYLEKQQELLRQRLEREAREAAELEEASAESEDEMIHPEGVASL 182
Query: 366 LQGSEGNKVKRTSCMYGANCYRKNPVHFQHFSHPGDSDYGGVQIVGQDETDDRPECPYGP 425
L + ++R + RK+ + GDSD D++P
Sbjct: 183 LPPDFQSSLERPELELSRHSPRKSSSISEE---KGDSD------------DEKPRKGERR 227
Query: 426 SCYRKNPQHKIEYRHNTLPVRNVLDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDW 485
S R + + P D++ + D N ++EEE+ E +ED +
Sbjct: 228 SS-RVRQARAAKLSEGSQPAEEEEDQETPSRNLRVRADRNLK-TEEEEEEEEEEEEDDEE 285
Query: 486 EPGKEDEEKEDVEELLKEAK 505
E G ++ +K +LKE K
Sbjct: 286 EEGDDEGQKSREAPILKEFK 305
>gi|22035548 amyloid beta A4 precursor protein-binding, family A,
member 1 [Homo sapiens]
Length = 837
Score = 36.6 bits (83), Expect = 0.056
Identities = 37/180 (20%), Positives = 75/180 (41%), Gaps = 26/180 (14%)
Query: 332 QGDSLQDESQGSHSESSSNPSNPETLHAKATDSVLQGSEGNKVKRTSCMYGANCYRKNPV 391
+ + ++++ H+E++ + P LH + L+ E + +Y + +
Sbjct: 125 EAEEYTEQAEAEHAEATHRRALPNHLHFHS----LEHEEAMNAAYSGYVYTHRLFHRG-- 178
Query: 392 HFQHFSHPGDSDYGGVQIVGQDETDDRPECPY--GPSCYRKNPQHKIEYRHNTLPVR-NV 448
+ +S P +DYGG+Q +E D PE G Y + YR L R +
Sbjct: 179 EDEPYSEPY-ADYGGLQEHVYEEIGDAPELDARDGLRLYEQERDEAAAYRQEALGARLHH 237
Query: 449 LDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDWEPGKEDEEKEDVEELLKEAKRFM 508
DE +D +S ++E ++ P + E++ED+++++ E K+ M
Sbjct: 238 YDERSD----------GESDSPEKEAEFAPYPRMDSY------EQEEDIDQIVAEVKQSM 281
>gi|23957698 luman-recruiting factor [Homo sapiens]
Length = 639
Score = 36.6 bits (83), Expect = 0.056
Identities = 22/65 (33%), Positives = 40/65 (61%), Gaps = 6/65 (9%)
Query: 447 NVLDEDNDNVGQPNEYDLNDSFLDDEEEDYEPTDEDSDW-----EPGKEDEEKEDVEELL 501
+V DED+D G +E++L+++ ++EEE+ D+D D EPG E++ ED++E+
Sbjct: 363 DVDDEDHDE-GFGSEHELSENEEEEEEEEDYEDDKDDDISDTFSEPGYENDSVEDLKEVT 421
Query: 502 KEAKR 506
+ R
Sbjct: 422 SISSR 426
>gi|21327708 nucleosome assembly protein 1-like 1 [Homo sapiens]
Length = 391
Score = 36.2 bits (82), Expect = 0.073
Identities = 13/27 (48%), Positives = 21/27 (77%)
Query: 476 YEPTDEDSDWEPGKEDEEKEDVEELLK 502
YEPT+E+ +W+P +EDE E+++E K
Sbjct: 125 YEPTEEECEWKPDEEDEISEELKEKAK 151
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.128 0.370
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 22,109,807
Number of Sequences: 37866
Number of extensions: 1113991
Number of successful extensions: 7916
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 116
Number of HSP's successfully gapped in prelim test: 230
Number of HSP's that attempted gapping in prelim test: 5611
Number of HSP's gapped (non-prelim): 1757
length of query: 511
length of database: 18,247,518
effective HSP length: 107
effective length of query: 404
effective length of database: 14,195,856
effective search space: 5735125824
effective search space used: 5735125824
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.