BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|27436964 potassium voltage-gated channel, shaker-related subfamily, beta member 1 isoform 3 [Homo sapiens] (401 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|27436964 potassium voltage-gated channel, shaker-related subf... 800 0.0 gi|27436962 potassium voltage-gated channel, shaker-related subf... 680 0.0 gi|27436966 potassium voltage-gated channel, shaker-related subf... 672 0.0 gi|27436969 potassium voltage-gated channel, shaker-related subf... 588 e-168 gi|4504825 potassium voltage-gated channel, shaker-related subfa... 587 e-168 gi|27436971 potassium voltage-gated channel, shaker-related subf... 550 e-157 gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo s... 84 3e-16 gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens] 81 2e-15 gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens] 80 3e-15 gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo s... 61 2e-09 gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens] 44 2e-04 gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens] 44 2e-04 gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens] 43 4e-04 gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens] 42 0.001 gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens] 42 0.001 gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens] 39 0.006 gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens] 39 0.008 gi|122937516 aldo-keto reductase family 1, member B10-like [Homo... 37 0.041 gi|207028673 hypothetical protein LOC100134257 [Homo sapiens] 35 0.12 gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens] 33 0.46 gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens] 31 2.3 gi|122937392 chromosome 19 open reading frame 29 [Homo sapiens] 31 2.3 gi|163310749 LIM and calponin homology domains 1 isoform e [Homo... 29 8.6 gi|163310747 LIM and calponin homology domains 1 isoform d [Homo... 29 8.6 gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 29 8.6 >gi|27436964 potassium voltage-gated channel, shaker-related subfamily, beta member 1 isoform 3 [Homo sapiens] Length = 401 Score = 800 bits (2067), Expect = 0.0 Identities = 401/401 (100%), Positives = 401/401 (100%) Query: 1 MQVSIACTEHNLKSRNGEDRLLSKQSSTAPNVVNAARAKFRTVAIIARSLGTFTPQHHIS 60 MQVSIACTEHNLKSRNGEDRLLSKQSSTAPNVVNAARAKFRTVAIIARSLGTFTPQHHIS Sbjct: 1 MQVSIACTEHNLKSRNGEDRLLSKQSSTAPNVVNAARAKFRTVAIIARSLGTFTPQHHIS 60 Query: 61 LKESTAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDT 120 LKESTAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDT Sbjct: 61 LKESTAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDT 120 Query: 121 AEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQR 180 AEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQR Sbjct: 121 AEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQR 180 Query: 181 LQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFN 240 LQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFN Sbjct: 181 LQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFN 240 Query: 241 MIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRAS 300 MIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRAS Sbjct: 241 MIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRAS 300 Query: 301 LKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSST 360 LKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSST Sbjct: 301 LKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSST 360 Query: 361 PEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 401 PEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS Sbjct: 361 PEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 401 >gi|27436962 potassium voltage-gated channel, shaker-related subfamily, beta member 1 isoform 2 [Homo sapiens] Length = 408 Score = 680 bits (1755), Expect = 0.0 Identities = 339/349 (97%), Positives = 342/349 (97%) Query: 53 FTPQHHISLKESTAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYE 112 F H ISL+E+T +TGM YRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYE Sbjct: 60 FLRVHGISLQETTRAETGMAYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYE 119 Query: 113 SGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIE 172 SGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIE Sbjct: 120 SGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIE 179 Query: 173 GLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEA 232 GLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEA Sbjct: 180 GLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEA 239 Query: 233 YSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNG 292 YSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNG Sbjct: 240 YSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNG 299 Query: 293 VPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVS 352 VPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVS Sbjct: 300 VPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVS 359 Query: 353 SVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 401 SVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS Sbjct: 360 SVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 408 >gi|27436966 potassium voltage-gated channel, shaker-related subfamily, beta member 1 isoform 1 [Homo sapiens] Length = 419 Score = 672 bits (1733), Expect = 0.0 Identities = 341/380 (89%), Positives = 354/380 (93%), Gaps = 3/380 (0%) Query: 23 SKQSSTAPNVVNAARAKFRTVAIIAR-SLGTFTPQHHISLKESTAKQTGMKYRNLGKSGL 81 +K SS +P+ + RA R +A++ + + +S + +T TGM +RNLGKSGL Sbjct: 42 AKDSSLSPSGESQLRA--RQLALLREVEMNWYLKLCDLSSEHTTVCTTGMPHRNLGKSGL 99 Query: 82 RVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKG 141 RVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKG Sbjct: 100 RVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKG 159 Query: 142 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 201 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME Sbjct: 160 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 219 Query: 202 EIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEV 261 EIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEV Sbjct: 220 EIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEV 279 Query: 262 QLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQN 321 QLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQN Sbjct: 280 QLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEGRKQQN 339 Query: 322 KLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHV 381 KLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHV Sbjct: 340 KLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHV 399 Query: 382 VNEIDNILRNKPYSKKDYRS 401 VNEIDNILRNKPYSKKDYRS Sbjct: 400 VNEIDNILRNKPYSKKDYRS 419 >gi|27436969 potassium voltage-gated channel, shaker-related subfamily, beta member 2 isoform 2 [Homo sapiens] Length = 353 Score = 588 bits (1517), Expect = e-168 Identities = 280/332 (84%), Positives = 316/332 (95%) Query: 70 GMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKA 129 GM YRNLGKSGLRVSCLGLGTWVTFGGQI+DE+AE+LMT+AY++G+NLFDTAEVYAAGKA Sbjct: 22 GMIYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAYDNGINLFDTAEVYAAGKA 81 Query: 130 EVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVV 189 EV+LG+IIKKKGWRRSSLVITTK++WGGKAETERGLSRKHIIEGLK SL+RLQLEYVDVV Sbjct: 82 EVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHIIEGLKASLERLQLEYVDVV 141 Query: 190 FANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQA 249 FANRPD NTPMEE VRAMTHVINQGMAMYWGTSRWS+MEIMEAYSVARQFN+ PP+CEQA Sbjct: 142 FANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIMEAYSVARQFNLTPPICEQA 201 Query: 250 EYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKE 309 EYH+FQREKVEVQLPEL+HKIGVGAMTWSPLACGI+SGKY +G+P SRASLK YQWLK+ Sbjct: 202 EYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDSGIPPYSRASLKGYQWLKD 261 Query: 310 RIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGVSSVLLGSSTPEQLIENLG 369 +I+SEEGR+QQ KLK+L IAERLGCTLPQLA+AWCLRNEGVSSVLLG+S +QL+EN+G Sbjct: 262 KILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGVSSVLLGASNADQLMENIG 321 Query: 370 AIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 401 AIQVLPK++S +++EID+IL NKPYSKKDYRS Sbjct: 322 AIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS 353 >gi|4504825 potassium voltage-gated channel, shaker-related subfamily, beta member 2 isoform 1 [Homo sapiens] Length = 367 Score = 587 bits (1512), Expect = e-168 Identities = 282/350 (80%), Positives = 322/350 (92%) Query: 52 TFTPQHHISLKESTAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAY 111 T +P S + + K+ YRNLGKSGLRVSCLGLGTWVTFGGQI+DE+AE+LMT+AY Sbjct: 18 TGSPGMIYSTRYGSPKRQLQFYRNLGKSGLRVSCLGLGTWVTFGGQITDEMAEQLMTLAY 77 Query: 112 ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHII 171 ++G+NLFDTAEVYAAGKAEV+LG+IIKKKGWRRSSLVITTK++WGGKAETERGLSRKHII Sbjct: 78 DNGINLFDTAEVYAAGKAEVVLGNIIKKKGWRRSSLVITTKIFWGGKAETERGLSRKHII 137 Query: 172 EGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIME 231 EGLK SL+RLQLEYVDVVFANRPD NTPMEE VRAMTHVINQGMAMYWGTSRWS+MEIME Sbjct: 138 EGLKASLERLQLEYVDVVFANRPDPNTPMEETVRAMTHVINQGMAMYWGTSRWSSMEIME 197 Query: 232 AYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGN 291 AYSVARQFN+ PP+CEQAEYH+FQREKVEVQLPEL+HKIGVGAMTWSPLACGI+SGKY + Sbjct: 198 AYSVARQFNLTPPICEQAEYHMFQREKVEVQLPELFHKIGVGAMTWSPLACGIVSGKYDS 257 Query: 292 GVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLRNEGV 351 G+P SRASLK YQWLK++I+SEEGR+QQ KLK+L IAERLGCTLPQLA+AWCLRNEGV Sbjct: 258 GIPPYSRASLKGYQWLKDKILSEEGRRQQAKLKELQAIAERLGCTLPQLAIAWCLRNEGV 317 Query: 352 SSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKKDYRS 401 SSVLLG+S +QL+EN+GAIQVLPK++S +++EID+IL NKPYSKKDYRS Sbjct: 318 SSVLLGASNADQLMENIGAIQVLPKLSSSIIHEIDSILGNKPYSKKDYRS 367 >gi|27436971 potassium voltage-gated channel, shaker-related subfamily, beta member 3 [Homo sapiens] Length = 404 Score = 550 bits (1417), Expect = e-157 Identities = 277/410 (67%), Positives = 329/410 (80%), Gaps = 19/410 (4%) Query: 1 MQVSIACTEHNLKSRNGEDRLLSKQSSTA-------------PNVVNAARAKFRTVAIIA 47 MQVSIACTE NL+SR+ EDRL + P + K R A++ Sbjct: 1 MQVSIACTEQNLRSRSSEDRLCGPRPGPGGGNGGPAGGGHGNPPGGGGSGPKARA-ALVP 59 Query: 48 RSLGTFTPQHHISLKESTAKQTGMKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLM 107 R P +L+EST + TGMKYRNLGKSGLRVSCLGLGTWVTFG QISDE AE ++ Sbjct: 60 RP-----PAPAGALRESTGRGTGMKYRNLGKSGLRVSCLGLGTWVTFGSQISDETAEDVL 114 Query: 108 TIAYESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSR 167 T+AYE GVNLFDTAEVYAAGKAE LG+I+K KGWRRSS VITTK++WGG+AETERGLSR Sbjct: 115 TVAYEHGVNLFDTAEVYAAGKAERTLGNILKSKGWRRSSYVITTKIFWGGQAETERGLSR 174 Query: 168 KHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAM 227 KHIIEGL+GSL+RLQL YVD+VFANR D N PMEEIVRAMT+VINQG+A+YWGTSRW A Sbjct: 175 KHIIEGLRGSLERLQLGYVDIVFANRSDPNCPMEEIVRAMTYVINQGLALYWGTSRWGAA 234 Query: 228 EIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISG 287 EIMEAYS+ARQFN+IPPVCEQAE+HLFQREKVE+QLPELYHKIGVG++TW PLACG+I+ Sbjct: 235 EIMEAYSMARQFNLIPPVCEQAEHHLFQREKVEMQLPELYHKIGVGSVTWYPLACGLITS 294 Query: 288 KYGNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIAERLGCTLPQLAVAWCLR 347 KY VP++ RAS+K YQWLK+++ SE+G+KQQ K+ DL P+A +LGCT+ QLA+AWCLR Sbjct: 295 KYDGRVPDTCRASIKGYQWLKDKVQSEDGKKQQAKVMDLLPVAHQLGCTVAQLAIAWCLR 354 Query: 348 NEGVSSVLLGSSTPEQLIENLGAIQVLPKMTSHVVNEIDNILRNKPYSKK 397 +EGVSSVLLG S+ EQLIE+LGA+QVL ++T V EID +L NKP+SKK Sbjct: 355 SEGVSSVLLGVSSAEQLIEHLGALQVLSQLTPQTVMEIDGLLGNKPHSKK 404 >gi|223718702 aflatoxin B1 aldehyde reductase 3 isoform 1 [Homo sapiens] Length = 331 Score = 83.6 bits (205), Expect = 3e-16 Identities = 78/296 (26%), Positives = 138/296 (46%), Gaps = 25/296 (8%) Query: 96 GQISDEVAERLMTIAY-ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY 154 G+ D +T A+ E G DTA +Y+ G++E ILG + + G + I TK Sbjct: 20 GRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVKIATKAN 79 Query: 155 -WGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQ 213 W G + L + L+ SL+RLQ VD+ + + PD + P+EE +RA + + Sbjct: 80 PWIGNS-----LKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQE 134 Query: 214 GMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVG 273 G + G S ++A E+ E ++ + I P Q Y R+ VE +L G+ Sbjct: 135 GKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYSATTRQ-VETELFPCLRHFGLR 193 Query: 274 AMTWSPLACGIISGKYGNGVPESSRASLKCY--QWLKERIVSEEGRKQQNKLKDLSPIAE 331 ++PLA G+++GKY + + + + QW + + +++ + ++ + + Sbjct: 194 FYAYNPLAGGLLTGKYKYEDKDGKQPVGRFFGTQWAE---IYRNHFWKEHHFEGIALVEK 250 Query: 332 RL----GCTLPQL---AVAWC-----LRNEGVSSVLLGSSTPEQLIENLGAIQVLP 375 L G + P + A+ W L+ +V+LG S+ EQL +NL A + P Sbjct: 251 ALQAAYGASAPSMTSAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGP 306 >gi|41152114 aldo-keto reductase family 7, member A3 [Homo sapiens] Length = 331 Score = 80.9 bits (198), Expect = 2e-15 Identities = 80/293 (27%), Positives = 130/293 (44%), Gaps = 19/293 (6%) Query: 96 GQISDEVAERLMTIAY-ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY 154 G+ D +T A+ E G DTA VY+ G++E ILG + + G + I TK Sbjct: 20 GRRMDAPTSAAVTRAFLERGHTEIDTAFVYSEGQSETILGGLGLRLGGSDCRVKIDTKAI 79 Query: 155 WGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQG 214 L + L+ SL+RLQ VD+ + + PD +TP+EE +RA + +G Sbjct: 80 ----PLFGNSLKPDSLRFQLETSLKRLQCPRVDLFYLHMPDHSTPVEETLRACHQLHQEG 135 Query: 215 MAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGA 274 + G S ++A E+ E ++ + I P Q Y+ R+ VE +L G+ Sbjct: 136 KFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQGMYNAITRQ-VETELFPCLRHFGLRF 194 Query: 275 MTWSPLACGIISGKY----GNGVPESSRASLKCYQWLKERIVSEEGRKQQNKLKDLSPIA 330 ++PLA G+++GKY NG R + + +E + L + + Sbjct: 195 YAFNPLAGGLLTGKYKYEDKNGKQPVGRFFGNTWAEMYRNRYWKEHHFEGIALVE-KALQ 253 Query: 331 ERLGCTLPQLAVA---WC-----LRNEGVSSVLLGSSTPEQLIENLGAIQVLP 375 G + P + A W L+ +V+LG S+ EQL +NL A + P Sbjct: 254 AAYGASAPSMTSATLRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAAAEEGP 306 >gi|41327764 aldo-keto reductase family 7, member A2 [Homo sapiens] Length = 359 Score = 80.1 bits (196), Expect = 3e-15 Identities = 77/282 (27%), Positives = 126/282 (44%), Gaps = 30/282 (10%) Query: 112 ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY-WGGKAETERGLSRKHI 170 E G DTA +Y+ G++E ILG + G + I TK W GK+ L + Sbjct: 65 ERGHTELDTAFMYSDGQSETILGGLGLGLGGGDCRVKIATKANPWDGKS-----LKPDSV 119 Query: 171 IEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIM 230 L+ SL+RLQ VD+ + + PD TP+EE + A + +G + G S +++ E+ Sbjct: 120 RSQLETSLKRLQCPQVDLFYLHAPDHGTPVEETLHACQRLHQEGKFVELGLSNYASWEVA 179 Query: 231 EAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPLACGIISGKYG 290 E ++ + I P Q Y+ R+ VE +L G+ ++PLA G+++GKY Sbjct: 180 EICTLCKSNGWILPTVYQGMYNATTRQ-VETELFPCLRHFGLRFYAYNPLAGGLLTGKYK 238 Query: 291 NGVPESSRASLKCY--QWLKERIVSEEGRKQQNKLKDLSPIA-------ERLGCTLPQL- 340 + + + + W +E R + K IA G + P + Sbjct: 239 YEDKDGKQPVGRFFGNSW------AETYRNRFWKEHHFEAIALVEKALQAAYGASAPSVT 292 Query: 341 --AVAWC-----LRNEGVSSVLLGSSTPEQLIENLGAIQVLP 375 A+ W L+ +V+LG S+ EQL +NL A + P Sbjct: 293 SAALRWMYHHSQLQGAHGDAVILGMSSLEQLEQNLAATEEGP 334 >gi|223718708 aflatoxin B1 aldehyde reductase 3 isoform 2 [Homo sapiens] Length = 249 Score = 61.2 bits (147), Expect = 2e-09 Identities = 46/155 (29%), Positives = 75/155 (48%), Gaps = 7/155 (4%) Query: 96 GQISDEVAERLMTIAY-ESGVNLFDTAEVYAAGKAEVILGSIIKKKGWRRSSLVITTKLY 154 G+ D +T A+ E G DTA +Y+ G++E ILG + + G + I TK Sbjct: 20 GRRMDAPTSAAVTRAFLERGHTEIDTAFLYSDGQSETILGGLGLRMGSSDCRVKIATKAN 79 Query: 155 -WGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPMEEIVRAMTHVINQ 213 W G + L + L+ SL+RLQ VD+ + + PD + P+EE +RA + + Sbjct: 80 PWIGNS-----LKPDSVRSQLETSLKRLQCPUVDLFYLHAPDHSAPVEETLRACHQLHQE 134 Query: 214 GMAMYWGTSRWSAMEIMEAYSVARQFNMIPPVCEQ 248 G + G S ++A E+ E ++ + I P Q Sbjct: 135 GKFVELGLSNYAAWEVAEICTLCKSNGWILPTVYQ 169 >gi|24497577 aldo-keto reductase family 1, member A1 [Homo sapiens] Length = 325 Score = 44.3 bits (103), Expect = 2e-04 Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 43/198 (21%) Query: 79 SGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIK 138 +G ++ +GLGTW + GQ+ V A G D A +Y E +G +K Sbjct: 10 TGQKMPLIGLGTWKSEPGQVKAAV-----KYALSVGYRHIDCAAIYG---NEPEIGEALK 61 Query: 139 K-----KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANR 193 + K R L +T+KL W K E + L+ +L LQLEY+D+ + Sbjct: 62 EDVGPGKAVPREELFVTSKL-WNTKHHPE------DVEPALRKTLADLQLEYLDLYLMHW 114 Query: 194 PDS-------------------NTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYS 234 P + +T +E +A+ ++ +G+ G S +++ +I + S Sbjct: 115 PYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILS 174 Query: 235 VARQFNMIPPVCEQAEYH 252 VA + P Q E H Sbjct: 175 VA----SVRPAVLQVECH 188 >gi|5174391 aldo-keto reductase family 1, member A1 [Homo sapiens] Length = 325 Score = 44.3 bits (103), Expect = 2e-04 Identities = 49/198 (24%), Positives = 82/198 (41%), Gaps = 43/198 (21%) Query: 79 SGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIK 138 +G ++ +GLGTW + GQ+ V A G D A +Y E +G +K Sbjct: 10 TGQKMPLIGLGTWKSEPGQVKAAV-----KYALSVGYRHIDCAAIYG---NEPEIGEALK 61 Query: 139 K-----KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANR 193 + K R L +T+KL W K E + L+ +L LQLEY+D+ + Sbjct: 62 EDVGPGKAVPREELFVTSKL-WNTKHHPE------DVEPALRKTLADLQLEYLDLYLMHW 114 Query: 194 PDS-------------------NTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYS 234 P + +T +E +A+ ++ +G+ G S +++ +I + S Sbjct: 115 PYAFERGDNPFPKNADGTICYDSTHYKETWKALEALVAKGLVQALGLSNFNSRQIDDILS 174 Query: 235 VARQFNMIPPVCEQAEYH 252 VA + P Q E H Sbjct: 175 VA----SVRPAVLQVECH 188 >gi|4502049 aldo-keto reductase family 1, member B1 [Homo sapiens] Length = 316 Score = 43.1 bits (100), Expect = 4e-04 Identities = 52/234 (22%), Positives = 99/234 (42%), Gaps = 45/234 (19%) Query: 71 MKYRNLGKSGLRVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYA-AGKA 129 M R L +G ++ LGLGTW + GQ+++ V +A + G D A VY + Sbjct: 1 MASRLLLNNGAKMPILGLGTWKSPPGQVTEAV-----KVAIDVGYRHIDCAHVYQNENEV 55 Query: 130 EVILGSIIKKKGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQR----LQLEY 185 V + ++++ +R L I +KL+ E+GL +KG+ Q+ L+L+Y Sbjct: 56 GVAIQEKLREQVVKREELFIVSKLWC---TYHEKGL--------VKGACQKTLSDLKLDY 104 Query: 186 VDVVFANRPDSNTPMEEIV-------------------RAMTHVINQGMAMYWGTSRWSA 226 +D+ + P P +E AM ++++G+ G S ++ Sbjct: 105 LDLYLIHWPTGFKPGKEFFPLDESGNVVPSDTNILDTWAAMEELVDEGLVKAIGISNFNH 164 Query: 227 MEIMEAYSVARQFNMIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPL 280 +++ + + P Q E H + ++ +L + G+ +SPL Sbjct: 165 LQV--EMILNKPGLKYKPAVNQIECHPYLTQE---KLIQYCQSKGIVVTAYSPL 213 >gi|45446745 aldo-keto reductase family 1, member C2 [Homo sapiens] Length = 323 Score = 42.0 bits (97), Expect = 0.001 Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 43/199 (21%) Query: 86 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 141 LG GT+ ++ A + +A E+G + D+A VY E +G I+ K Sbjct: 19 LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73 Query: 142 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 201 +R + T+KL W E + L+ SL+ LQL+YVD+ + P S P E Sbjct: 74 VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126 Query: 202 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVARQFNM---------------- 241 E++ ++ + + T + W AME + +A+ + Sbjct: 127 EVIPK-----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181 Query: 242 --IPPVCEQAEYHLFQREK 258 PVC Q E H + ++ Sbjct: 182 LKYKPVCNQVECHPYFNQR 200 >gi|4503285 aldo-keto reductase family 1, member C2 [Homo sapiens] Length = 323 Score = 42.0 bits (97), Expect = 0.001 Identities = 48/199 (24%), Positives = 81/199 (40%), Gaps = 43/199 (21%) Query: 86 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 141 LG GT+ ++ A + +A E+G + D+A VY E +G I+ K Sbjct: 19 LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73 Query: 142 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 201 +R + T+KL W E + L+ SL+ LQL+YVD+ + P S P E Sbjct: 74 VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126 Query: 202 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVARQFNM---------------- 241 E++ ++ + + T + W AME + +A+ + Sbjct: 127 EVIPK-----DENGKILFDTVDLCATWEAMEKCKDAGLAKSIGVSNFNHRLLEMILNKPG 181 Query: 242 --IPPVCEQAEYHLFQREK 258 PVC Q E H + ++ Sbjct: 182 LKYKPVCNQVECHPYFNQR 200 >gi|5453543 aldo-keto reductase family 1, member C1 [Homo sapiens] Length = 323 Score = 39.3 bits (90), Expect = 0.006 Identities = 50/199 (25%), Positives = 81/199 (40%), Gaps = 43/199 (21%) Query: 86 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 141 LG GT+ ++ A +A E+G D+A +Y E +G I+ K Sbjct: 19 LGFGTYAP--AEVPKSKALEATKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73 Query: 142 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDSNTPME 201 +R + T+KL W E + L+ SL+ LQL+YVD+ + P S P E Sbjct: 74 VKREDIFYTSKL-WCNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVSVKPGE 126 Query: 202 EIVRAMTHVINQGMAMYWGT----SRWSAMEIMEAYSVA----------RQFNMI----- 242 E++ ++ + + T + W A+E + +A RQ MI Sbjct: 127 EVIPK-----DENGKILFDTVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181 Query: 243 ---PPVCEQAEYHLFQREK 258 PVC Q E H + ++ Sbjct: 182 LKYKPVCNQVECHPYFNQR 200 >gi|24497583 aldo-keto reductase family 1, member C3 [Homo sapiens] Length = 323 Score = 38.9 bits (89), Expect = 0.008 Identities = 52/201 (25%), Positives = 82/201 (40%), Gaps = 44/201 (21%) Query: 86 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 141 LG GT+ ++ A + +A E+G D+A +Y E +G I+ K Sbjct: 19 LGFGTYAP--PEVPRSKALEVTKLAIEAGFRHIDSAHLY---NNEEQVGLAIRSKIADGS 73 Query: 142 WRRSSLVITTKLYWGGKAETERGLSRKHIIE-GLKGSLQRLQLEYVDVVFANRPDSNTPM 200 +R + T+KL+ R ++ L+ SL++ QL+YVD+ + P S P Sbjct: 74 VKREDIFYTSKLW--------STFHRPELVRPALENSLKKAQLDYVDLYLIHSPMSLKPG 125 Query: 201 EEIVRAMTHVINQGMAMYWGT---SRWSAMEIMEAYSVA----------RQFNMI----- 242 EE ++ G ++ + W AME + +A RQ MI Sbjct: 126 EE----LSPTDENGKVIFDIVDLCTTWEAMEKCKDAGLAKSIGVSNFNRRQLEMILNKPG 181 Query: 243 ---PPVCEQAEYH-LFQREKV 259 PVC Q E H F R K+ Sbjct: 182 LKYKPVCNQVECHPYFNRSKL 202 >gi|122937516 aldo-keto reductase family 1, member B10-like [Homo sapiens] Length = 316 Score = 36.6 bits (83), Expect = 0.041 Identities = 50/220 (22%), Positives = 92/220 (41%), Gaps = 39/220 (17%) Query: 82 RVSCLGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEV--ILGSIIKK 139 ++ +GLGTW + G++ + V +A ++ D A Y + EV + I++ Sbjct: 12 KMPIVGLGTWRSLLGKVKEAV-----KVAIDAEYRHIDCAYFY-ENQHEVGEAIQEKIQE 65 Query: 140 KGWRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRP----- 194 K R L I +K++ ER L RK + +L+ L+L Y+DV + P Sbjct: 66 KAVMREDLFIVSKVW---PTFFERPLVRK----AFEKTLKDLKLSYLDVYLIHWPQGFKT 118 Query: 195 -DSNTPME-------------EIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVARQFN 240 D P + + AM ++++G+ G S ++ +I + + Sbjct: 119 GDDFFPKDDKGNMISGKGTFLDAWEAMEELVDEGLVKALGVSNFNHFQIERLLN--KPGL 176 Query: 241 MIPPVCEQAEYHLFQREKVEVQLPELYHKIGVGAMTWSPL 280 PV Q E H + ++ +L + H G+ +SPL Sbjct: 177 KYKPVTNQVECHPYLTQE---KLIQYCHSKGITVTAYSPL 213 >gi|207028673 hypothetical protein LOC100134257 [Homo sapiens] Length = 139 Score = 35.0 bits (79), Expect = 0.12 Identities = 33/115 (28%), Positives = 52/115 (45%), Gaps = 16/115 (13%) Query: 86 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 141 LG GT+ ++ A + +A E+G + D+A VY E +G I+ K Sbjct: 19 LGFGTYAP--AEVPKSKALEAVKLAIEAGFHHIDSAHVY---NNEEQVGLAIRSKIADGS 73 Query: 142 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRPDS 196 +R + T+KL W E + L+ SL+ LQL+YVD+ + P S Sbjct: 74 VKREDIFYTSKL-WSNSHRPEL------VRPALERSLKNLQLDYVDLYLIHFPVS 121 >gi|24497585 aldo-keto reductase family 1, member C4 [Homo sapiens] Length = 323 Score = 33.1 bits (74), Expect = 0.46 Identities = 45/195 (23%), Positives = 78/195 (40%), Gaps = 47/195 (24%) Query: 86 LGLGTWVTFGGQISDEVAERLMTIAYESGVNLFDTAEVYAAGKAEVILGSIIKKK----G 141 LG GT+ ++ A + +A E+G D+A +Y E +G I+ K Sbjct: 19 LGFGTYAP--PEVPRNRAVEVTKLAIEAGFRHIDSAYLY---NNEEQVGLAIRSKIADGS 73 Query: 142 WRRSSLVITTKLYWGGKAETERGLSRKHIIEGLKGSLQRLQLEYVDVVFANRP------D 195 +R + T+KL+ + + L+ SL++LQL+YVD+ + P + Sbjct: 74 VKREDIFYTSKLWC-------TFFQPQMVQPALESSLKKLQLDYVDLYLLHFPMALKPGE 126 Query: 196 SNTPMEEIVRAMTHVINQGMAMYWGTSRWSAMEIMEAYSVA----------RQFNMI--- 242 + P +E + + ++ ++ W ME + +A RQ MI Sbjct: 127 TPLPKDENGKVIFDTVDL-------SATWEVMEKCKDAGLAKSIGVSNFNCRQLEMILNK 179 Query: 243 -----PPVCEQAEYH 252 PVC Q E H Sbjct: 180 PGLKYKPVCNQVECH 194 >gi|126723149 chromosome 19 open reading frame 29 [Homo sapiens] Length = 758 Score = 30.8 bits (68), Expect = 2.3 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%) Query: 274 AMTWSPLACGIISGKYGNGV-PESSRASLKCYQWLKERIVSEEGRKQQNKL 323 A +WSP + S G P ++ A+L Q L+ER+ E RKQQ +L Sbjct: 106 ARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEEL 156 >gi|122937392 chromosome 19 open reading frame 29 [Homo sapiens] Length = 758 Score = 30.8 bits (68), Expect = 2.3 Identities = 19/51 (37%), Positives = 27/51 (52%), Gaps = 1/51 (1%) Query: 274 AMTWSPLACGIISGKYGNGV-PESSRASLKCYQWLKERIVSEEGRKQQNKL 323 A +WSP + S G P ++ A+L Q L+ER+ E RKQQ +L Sbjct: 106 ARSWSPSSSASSSASPGRSQSPRAAAAALSQQQSLQERLRLREERKQQEEL 156 >gi|163310749 LIM and calponin homology domains 1 isoform e [Homo sapiens] Length = 890 Score = 28.9 bits (63), Expect = 8.6 Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 3/69 (4%) Query: 257 EKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEG 316 E ++ LP L ++ + SP+ K+ PE R + +Q +ER++ E Sbjct: 569 EANQLHLPNLNSQVDSPSSEKSPVMTPF---KFWAWDPEEERRRQEKWQQEQERLLQERY 625 Query: 317 RKQQNKLKD 325 +K+Q+KLK+ Sbjct: 626 QKEQDKLKE 634 >gi|163310747 LIM and calponin homology domains 1 isoform d [Homo sapiens] Length = 902 Score = 28.9 bits (63), Expect = 8.6 Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 3/69 (4%) Query: 257 EKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEG 316 E ++ LP L ++ + SP+ K+ PE R + +Q +ER++ E Sbjct: 581 EANQLHLPNLNSQVDSPSSEKSPVMTPF---KFWAWDPEEERRRQEKWQQEQERLLQERY 637 Query: 317 RKQQNKLKD 325 +K+Q+KLK+ Sbjct: 638 QKEQDKLKE 646 >gi|163310745 LIM and calponin homology domains 1 isoform c [Homo sapiens] Length = 1056 Score = 28.9 bits (63), Expect = 8.6 Identities = 19/69 (27%), Positives = 35/69 (50%), Gaps = 3/69 (4%) Query: 257 EKVEVQLPELYHKIGVGAMTWSPLACGIISGKYGNGVPESSRASLKCYQWLKERIVSEEG 316 E ++ LP L ++ + SP+ K+ PE R + +Q +ER++ E Sbjct: 735 EANQLHLPNLNSQVDSPSSEKSPVMTPF---KFWAWDPEEERRRQEKWQQEQERLLQERY 791 Query: 317 RKQQNKLKD 325 +K+Q+KLK+ Sbjct: 792 QKEQDKLKE 800 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.131 0.385 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 14,064,685 Number of Sequences: 37866 Number of extensions: 576077 Number of successful extensions: 1268 Number of sequences better than 10.0: 25 Number of HSP's better than 10.0 without gapping: 13 Number of HSP's successfully gapped in prelim test: 12 Number of HSP's that attempted gapping in prelim test: 1241 Number of HSP's gapped (non-prelim): 29 length of query: 401 length of database: 18,247,518 effective HSP length: 104 effective length of query: 297 effective length of database: 14,309,454 effective search space: 4249907838 effective search space used: 4249907838 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.