Search of human proteins with 26051262

Search of human proteins with 26051262

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|26051262 potassium voltage-gated channel KQT-like protein 2
isoform b [Homo sapiens]
         (854 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|26051262 potassium voltage-gated channel KQT-like protein 2 i...  1736   0.0  
gi|26051264 potassium voltage-gated channel KQT-like protein 2 i...  1725   0.0  
gi|26051260 potassium voltage-gated channel KQT-like protein 2 i...  1709   0.0  
gi|26051266 potassium voltage-gated channel KQT-like protein 2 i...  1699   0.0  
gi|26051268 potassium voltage-gated channel KQT-like protein 2 i...   759   0.0  
gi|236462079 potassium voltage-gated channel, KQT-like subfamily...   679   0.0  
gi|28373065 potassium voltage-gated channel, KQT-like subfamily,...   679   0.0  
gi|236461942 potassium voltage-gated channel, KQT-like subfamily...   676   0.0  
gi|236461719 potassium voltage-gated channel, KQT-like subfamily...   668   0.0  
gi|26638653 potassium voltage-gated channel KQT-like protein 4 i...   668   0.0  
gi|4758630 potassium voltage-gated channel KQT-like protein 3 [H...   665   0.0  
gi|26638655 potassium voltage-gated channel KQT-like protein 4 i...   661   0.0  
gi|236462242 potassium voltage-gated channel, KQT-like subfamily...   474   e-133
gi|32479527 potassium voltage-gated channel, KQT-like subfamily,...   400   e-111
gi|32479525 potassium voltage-gated channel, KQT-like subfamily,...   375   e-104
gi|21217561 Shaw-related voltage-gated potassium channel protein...   104   3e-22
gi|21217563 Shaw-related voltage-gated potassium channel protein...   104   3e-22
gi|24497458 Shaw-related voltage-gated potassium channel protein...   104   3e-22
gi|119395748 potassium voltage-gated channel subfamily A member ...    95   3e-19
gi|88758565 potassium voltage-gated channel, shaker-related subf...    94   5e-19
gi|4504817 potassium voltage-gated channel, shaker-related subfa...    94   5e-19
gi|4826784 potassium voltage-gated channel, Shab-related subfami...    92   2e-18
gi|163792201 Shaw-related voltage-gated potassium channel protei...    92   2e-18
gi|27436974 potassium voltage-gated channel, Shab-related subfam...    92   3e-18
gi|4826786 Shaw-related voltage-gated potassium channel protein ...    92   3e-18
gi|27436984 potassium voltage-gated channel, Shal-related subfam...    91   5e-18
gi|88758576 Shaw-related voltage-gated potassium channel protein...    90   1e-17
gi|24497462 Shaw-related voltage-gated potassium channel protein...    90   1e-17
gi|24497464 Shaw-related voltage-gated potassium channel protein...    90   1e-17
gi|4504821 potassium voltage-gated channel, shaker-related subfa...    89   2e-17

>gi|26051262 potassium voltage-gated channel KQT-like protein 2
           isoform b [Homo sapiens]
          Length = 854

 Score = 1736 bits (4496), Expect = 0.0
 Identities = 854/854 (100%), Positives = 854/854 (100%)

Query: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60
           MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
Sbjct: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60

Query: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120
           GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
Sbjct: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120

Query: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180
           SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
Sbjct: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180

Query: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
           AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
Sbjct: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240

Query: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300
           LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
Sbjct: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300

Query: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360
           GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
Sbjct: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360

Query: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVS 420
           QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVS
Sbjct: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVS 420

Query: 421 LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI 480
           LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI
Sbjct: 421 LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI 480

Query: 481 KGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES 540
           KGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES
Sbjct: 481 KGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES 540

Query: 541 LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS 600
           LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS
Sbjct: 541 LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS 600

Query: 601 MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE 660
           MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE
Sbjct: 601 MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE 660

Query: 661 HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS 720
           HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS
Sbjct: 661 HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS 720

Query: 721 LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL 780
           LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL
Sbjct: 721 LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL 780

Query: 781 ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG 840
           ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG
Sbjct: 781 ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG 840

Query: 841 EGPFGDVGWAGPRK 854
           EGPFGDVGWAGPRK
Sbjct: 841 EGPFGDVGWAGPRK 854


>gi|26051264 potassium voltage-gated channel KQT-like protein 2
           isoform a [Homo sapiens]
          Length = 872

 Score = 1725 bits (4467), Expect = 0.0
 Identities = 854/872 (97%), Positives = 854/872 (97%), Gaps = 18/872 (2%)

Query: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60
           MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
Sbjct: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60

Query: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120
           GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
Sbjct: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120

Query: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180
           SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
Sbjct: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180

Query: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
           AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
Sbjct: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240

Query: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300
           LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
Sbjct: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300

Query: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360
           GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
Sbjct: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360

Query: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPS---- 416
           QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPS    
Sbjct: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSKGSP 420

Query: 417 --------------QKVSLKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKV 462
                         QKVSLKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKV
Sbjct: 421 CRGPLCGCCPGRSSQKVSLKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKV 480

Query: 463 PKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSI 522
           PKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSI
Sbjct: 481 PKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSI 540

Query: 523 RAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAIT 582
           RAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAIT
Sbjct: 541 RAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAIT 600

Query: 583 DKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFG 642
           DKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFG
Sbjct: 601 DKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFG 660

Query: 643 AKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQP 702
           AKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQP
Sbjct: 661 AKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQP 720

Query: 703 QSHPRQGHGTSPVGDHGSLVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGN 762
           QSHPRQGHGTSPVGDHGSLVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGN
Sbjct: 721 QSHPRQGHGTSPVGDHGSLVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGN 780

Query: 763 LRDSDTSISIPSVDHEELERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESD 822
           LRDSDTSISIPSVDHEELERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESD
Sbjct: 781 LRDSDTSISIPSVDHEELERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESD 840

Query: 823 TDSDLCTPCGPPPRSATGEGPFGDVGWAGPRK 854
           TDSDLCTPCGPPPRSATGEGPFGDVGWAGPRK
Sbjct: 841 TDSDLCTPCGPPPRSATGEGPFGDVGWAGPRK 872


>gi|26051260 potassium voltage-gated channel KQT-like protein 2
           isoform c [Homo sapiens]
          Length = 844

 Score = 1709 bits (4426), Expect = 0.0
 Identities = 844/854 (98%), Positives = 844/854 (98%), Gaps = 10/854 (1%)

Query: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60
           MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
Sbjct: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60

Query: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120
           GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
Sbjct: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120

Query: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180
           SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
Sbjct: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180

Query: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
           AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
Sbjct: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240

Query: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300
           LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
Sbjct: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300

Query: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360
           GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
Sbjct: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360

Query: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVS 420
           QYYERTVTVPMY          RLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVS
Sbjct: 361 QYYERTVTVPMY----------RLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVS 410

Query: 421 LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI 480
           LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI
Sbjct: 411 LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI 470

Query: 481 KGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES 540
           KGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES
Sbjct: 471 KGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES 530

Query: 541 LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS 600
           LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS
Sbjct: 531 LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS 590

Query: 601 MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE 660
           MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE
Sbjct: 591 MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE 650

Query: 661 HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS 720
           HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS
Sbjct: 651 HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS 710

Query: 721 LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL 780
           LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL
Sbjct: 711 LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL 770

Query: 781 ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG 840
           ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG
Sbjct: 771 ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG 830

Query: 841 EGPFGDVGWAGPRK 854
           EGPFGDVGWAGPRK
Sbjct: 831 EGPFGDVGWAGPRK 844


>gi|26051266 potassium voltage-gated channel KQT-like protein 2
           isoform d [Homo sapiens]
          Length = 841

 Score = 1699 bits (4400), Expect = 0.0
 Identities = 841/854 (98%), Positives = 841/854 (98%), Gaps = 13/854 (1%)

Query: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60
           MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
Sbjct: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60

Query: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120
           GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
Sbjct: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120

Query: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180
           SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
Sbjct: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180

Query: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
           AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
Sbjct: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240

Query: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300
           LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
Sbjct: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300

Query: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360
           GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
Sbjct: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360

Query: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVS 420
           QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSP     
Sbjct: 361 QYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSP----- 415

Query: 421 LKDRVFSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI 480
                  SPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI
Sbjct: 416 -------SPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRI 468

Query: 481 KGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES 540
           KGAASRQNS EASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES
Sbjct: 469 KGAASRQNS-EASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKES 527

Query: 541 LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS 600
           LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS
Sbjct: 528 LRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDKDRTKGPAEAELPEDPS 587

Query: 601 MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE 660
           MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE
Sbjct: 588 MMGRLGKVEKQVLSMEKKLDFLVNIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSRE 647

Query: 661 HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS 720
           HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS
Sbjct: 648 HVDRHGCIVKIVRSSSSTGQKNFSAPPAAPPVQCPPSTSWQPQSHPRQGHGTSPVGDHGS 707

Query: 721 LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL 780
           LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL
Sbjct: 708 LVRIPPPPAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEEL 767

Query: 781 ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG 840
           ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG
Sbjct: 768 ERSFSGFSISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATG 827

Query: 841 EGPFGDVGWAGPRK 854
           EGPFGDVGWAGPRK
Sbjct: 828 EGPFGDVGWAGPRK 841


>gi|26051268 potassium voltage-gated channel KQT-like protein 2
           isoform e [Homo sapiens]
          Length = 393

 Score =  759 bits (1959), Expect = 0.0
 Identities = 372/372 (100%), Positives = 372/372 (100%)

Query: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60
           MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG
Sbjct: 1   MVQKSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGSEAPKRGSILSKPRAG 60

Query: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120
           GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK
Sbjct: 61  GAGAGKPPKRNAFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEK 120

Query: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180
           SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI
Sbjct: 121 SSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASI 180

Query: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
           AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF
Sbjct: 181 AVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240

Query: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300
           LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI
Sbjct: 241 LCLILASFLVYLAEKGENDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLI 300

Query: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360
           GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW
Sbjct: 301 GVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTW 360

Query: 361 QYYERTVTVPMY 372
           QYYERTVTVPMY
Sbjct: 361 QYYERTVTVPMY 372


>gi|236462079 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 4 [Homo sapiens]
          Length = 951

 Score =  679 bits (1751), Expect = 0.0
 Identities = 379/679 (55%), Positives = 463/679 (68%), Gaps = 43/679 (6%)

Query: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111

Query: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171

Query: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231

Query: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291

Query: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351

Query: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+ + + +     + + Q
Sbjct: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHTCSPTKKEQ 410

Query: 378 TYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVSLKDRV-FSSPRGVAAKG 436
              +S      N+ +L R   S+               SQK+S K+RV  +SPRG + K 
Sbjct: 411 GEASSSKFCS-NKQKLFRMYTSR-------------KQSQKLSFKERVRMASPRGQSIKS 456

Query: 437 KGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSE-EASLP 495
           + +      RRSPS D + E SP+KV KSWSF DR+R R + R+K +  +   + + +L 
Sbjct: 457 RQASVGD--RRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALG 514

Query: 496 GEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSA 555
            +D+ D+K C C+   EDLTP LK  IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSA
Sbjct: 515 TDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSA 574

Query: 556 GHLDMLSRIKSLQSRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLS 614
           GHLDML RIKSLQ+RVDQI+G+G   +D K R K  AE E  +D SM+GR+ KVEKQV S
Sbjct: 575 GHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQS 634

Query: 615 MEKKLDFLVNIYMQ--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGC 667
           +E KLD L++IY Q  R G       A F     E E    Y SP DS++        GC
Sbjct: 635 IESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGC 694

Query: 668 IVKIVRSSSSTGQKNFSAP 686
           + +   ++ S G +    P
Sbjct: 695 LSRSTSANISRGLQFILTP 713


>gi|28373065 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 1 [Homo sapiens]
          Length = 932

 Score =  679 bits (1751), Expect = 0.0
 Identities = 380/679 (55%), Positives = 456/679 (67%), Gaps = 62/679 (9%)

Query: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111

Query: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171

Query: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231

Query: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291

Query: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351

Query: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+                
Sbjct: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWK---------------- 394

Query: 378 TYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVSLKDRV-FSSPRGVAAKG 436
                   P L  L      K + G         E S SQK+S K+RV  +SPRG + K 
Sbjct: 395 --------PHLKALHTCSPTKKEQG---------EASSSQKLSFKERVRMASPRGQSIKS 437

Query: 437 KGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSE-EASLP 495
           + +      RRSPS D + E SP+KV KSWSF DR+R R + R+K +  +   + + +L 
Sbjct: 438 RQASVGD--RRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALG 495

Query: 496 GEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSA 555
            +D+ D+K C C+   EDLTP LK  IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSA
Sbjct: 496 TDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSA 555

Query: 556 GHLDMLSRIKSLQSRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLS 614
           GHLDML RIKSLQ+RVDQI+G+G   +D K R K  AE E  +D SM+GR+ KVEKQV S
Sbjct: 556 GHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQS 615

Query: 615 MEKKLDFLVNIYMQ--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGC 667
           +E KLD L++IY Q  R G       A F     E E    Y SP DS++        GC
Sbjct: 616 IESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGC 675

Query: 668 IVKIVRSSSSTGQKNFSAP 686
           + +   ++ S G +    P
Sbjct: 676 LSRSTSANISRGLQFILTP 694


>gi|236461942 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 3 [Homo sapiens]
          Length = 942

 Score =  676 bits (1745), Expect = 0.0
 Identities = 379/679 (55%), Positives = 462/679 (68%), Gaps = 52/679 (7%)

Query: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111

Query: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171

Query: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231

Query: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291

Query: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351

Query: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+ + + +      S T 
Sbjct: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHT---CSPTN 407

Query: 378 TYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVSLKDRV-FSSPRGVAAKG 436
            + +       N+ +L R   S+               SQK+S K+RV  +SPRG + K 
Sbjct: 408 KFCS-------NKQKLFRMYTSR-------------KQSQKLSFKERVRMASPRGQSIKS 447

Query: 437 KGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSE-EASLP 495
           + +      RRSPS D + E SP+KV KSWSF DR+R R + R+K +  +   + + +L 
Sbjct: 448 RQASVGD--RRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALG 505

Query: 496 GEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSA 555
            +D+ D+K C C+   EDLTP LK  IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSA
Sbjct: 506 TDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSA 565

Query: 556 GHLDMLSRIKSLQSRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLS 614
           GHLDML RIKSLQ+RVDQI+G+G   +D K R K  AE E  +D SM+GR+ KVEKQV S
Sbjct: 566 GHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQS 625

Query: 615 MEKKLDFLVNIYMQ--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGC 667
           +E KLD L++IY Q  R G       A F     E E    Y SP DS++        GC
Sbjct: 626 IESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGC 685

Query: 668 IVKIVRSSSSTGQKNFSAP 686
           + +   ++ S G +    P
Sbjct: 686 LSRSTSANISRGLQFILTP 704


>gi|236461719 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 2 [Homo sapiens]
          Length = 923

 Score =  668 bits (1723), Expect = 0.0
 Identities = 375/679 (55%), Positives = 453/679 (66%), Gaps = 71/679 (10%)

Query: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111

Query: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171

Query: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231

Query: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291

Query: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351

Query: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +             E++V++  +    +
Sbjct: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAAD-------------EKSVSIATWKPHLK 398

Query: 378 TYGASRLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVSLKDRV-FSSPRGVAAKG 436
              A     P N                           QK+S K+RV  +SPRG + K 
Sbjct: 399 ---ALHTCSPTN---------------------------QKLSFKERVRMASPRGQSIKS 428

Query: 437 KGSPQAQTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSE-EASLP 495
           + +      RRSPS D + E SP+KV KSWSF DR+R R + R+K +  +   + + +L 
Sbjct: 429 RQASVGD--RRSPSTDITAEGSPTKVQKSWSFNDRTRFRPSLRLKSSQPKPVIDADTALG 486

Query: 496 GEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSA 555
            +D+ D+K C C+   EDLTP LK  IRA+ +M+F V+KRKFKE+LRPYDV DVIEQYSA
Sbjct: 487 TDDVYDEKGCQCDVSVEDLTPPLKTVIRAIRIMKFHVAKRKFKETLRPYDVKDVIEQYSA 546

Query: 556 GHLDMLSRIKSLQSRVDQIVGRGPAITD-KDRTKGPAEAELPEDPSMMGRLGKVEKQVLS 614
           GHLDML RIKSLQ+RVDQI+G+G   +D K R K  AE E  +D SM+GR+ KVEKQV S
Sbjct: 547 GHLDMLCRIKSLQTRVDQILGKGQITSDKKSREKITAEHETTDDLSMLGRVVKVEKQVQS 606

Query: 615 MEKKLDFLVNIYMQ--RMGIPPTETEAYFGAK--EPEPAPPYHSPEDSRE---HVDRHGC 667
           +E KLD L++IY Q  R G       A F     E E    Y SP DS++        GC
Sbjct: 607 IESKLDCLLDIYQQVLRKGSASALALASFQIPPFECEQTSDYQSPVDSKDLSGSAQNSGC 666

Query: 668 IVKIVRSSSSTGQKNFSAP 686
           + +   ++ S G +    P
Sbjct: 667 LSRSTSANISRGLQFILTP 685


>gi|26638653 potassium voltage-gated channel KQT-like protein 4
           isoform a [Homo sapiens]
          Length = 695

 Score =  668 bits (1723), Expect = 0.0
 Identities = 363/679 (53%), Positives = 462/679 (68%), Gaps = 69/679 (10%)

Query: 44  GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91
           G  +P+R  +L  P   GA       G+G     +    +  YR+LQN++YNVLERPRGW
Sbjct: 38  GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97

Query: 92  AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151
           AF+YH ++FLLVFSCLVLSV STI+E+++ +   L ILE V IVVFG+EY VR+W+AGCC
Sbjct: 98  AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157

Query: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211
           CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM
Sbjct: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217

Query: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271
           DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK  N  F +YAD+LWWG
Sbjct: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277

Query: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331
            ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK
Sbjct: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337

Query: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQL 391
           RR PAA LIQ+AWR Y+T++SR  L +TW YY+                   ++P   +L
Sbjct: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYD------------------SILPSFREL 379

Query: 392 ELL--RNLKSKSG----LAFRKDPPPEPSPSQ---------------------KVSLKDR 424
            LL     ++++G    L  R+ P P+ +PS+                     ++ +KDR
Sbjct: 380 ALLFEHVQRARNGGLRPLEVRRAPVPDGAPSRYPPVATCHRPGSTSFCPGESSRMGIKDR 439

Query: 425 V-FSSPRGVAAKGKGSPQAQTVRRSPSADQSLE-DSPSKVPKSWSFGDRSRARQAFRIKG 482
           +   S +      K      T+  SPS++Q  E  SP+KV KSWSF DR+R R + R+K 
Sbjct: 440 IRMGSSQRRTGPSKQHLAPPTMPTSPSSEQVGEATSPTKVQKSWSFNDRTRFRASLRLK- 498

Query: 483 AASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLR 542
              R ++E+A  P E++ ++KS  CE   +D+ P +K  IR++ +++FLV+KRKFKE+LR
Sbjct: 499 --PRTSAEDA--PSEEVAEEKSYQCELTVDDIMPAVKTVIRSIRILKFLVAKRKFKETLR 554

Query: 543 PYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPA--ITDKDRTKGPAEAELPEDPS 600
           PYDV DVIEQYSAGHLDML RIKSLQ+RVDQIVGRGP      +   KGP++AE+ ++ S
Sbjct: 555 PYDVKDVIEQYSAGHLDMLGRIKSLQTRVDQIVGRGPGDRKAREKGDKGPSDAEVVDEIS 614

Query: 601 MMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGAKEPEPAPPYHSPEDS 658
           MMGR+ KVEKQV S+E KLD L+  Y +  R G   +         +P+    YHSP D 
Sbjct: 615 MMGRVVKVEKQVQSIEHKLDLLLGFYSRCLRSGTSASLGAVQVPLFDPDITSDYHSPVD- 673

Query: 659 REHVDRHGCIVKIVRSSSS 677
            E +      + I RS S+
Sbjct: 674 HEDISVSAQTLSISRSVST 692


>gi|4758630 potassium voltage-gated channel KQT-like protein 3 [Homo
           sapiens]
          Length = 872

 Score =  665 bits (1717), Expect = 0.0
 Identities = 419/907 (46%), Positives = 530/907 (58%), Gaps = 131/907 (14%)

Query: 4   KSRNGGVYPGPSGEKKLKVGFVGLDPGAPDSTRDGALLIAGS-------EAPKRGSILSK 56
           + R  G+ PG   +  L +G  G D       +DG LL+ G          P+   +L+K
Sbjct: 39  EERKVGLAPGDVEQVTLALG-AGAD-------KDGTLLLEGGGRDEGQRRTPQGIGLLAK 90

Query: 57  PRAGGAGAGKPPKRN-AFYRKLQNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTI 115
                    +P KRN A YR++Q  +Y+ LERPRGWA +YHA VFL+V  CL+L+V +T 
Sbjct: 91  -----TPLSRPVKRNNAKYRRIQTLIYDALERPRGWALLYHALVFLIVLGCLILAVLTTF 145

Query: 116 KEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMV 175
           KEYE  S   L +LE   I +FG E+ +RIWAAGCCCRY+GWRGRLKFARKP C++DI V
Sbjct: 146 KEYETVSGDWLLLLETFAIFIFGAEFALRIWAAGCCCRYKGWRGRLKFARKPLCMLDIFV 205

Query: 176 LIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
           LIAS+ V+A G+QGNV ATS LRSLRFLQILRM+RMDRRGGTWKLLGS + AHSKEL+TA
Sbjct: 206 LIASVPVVAVGNQGNVLATS-LRSLRFLQILRMLRMDRRGGTWKLLGSAICAHSKELITA 264

Query: 236 WYIGFLCLILASFLVYLAEK--------GEN--DHFDTYADALWWGLITLTTIGYGDKYP 285
           WYIGFL LIL+SFLVYL EK        GE   + F+TYADALWWGLITL TIGYGDK P
Sbjct: 265 WYIGFLTLILSSFLVYLVEKDVPEVDAQGEEMKEEFETYADALWWGLITLATIGYGDKTP 324

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWR 345
           +TW GRL+AATF+LIGVSFFALPAGILGSG ALKVQEQHRQKHFEKRR PAA LIQ+AWR
Sbjct: 325 KTWEGRLIAATFSLIGVSFFALPAGILGSGLALKVQEQHRQKHFEKRRKPAAELIQAAWR 384

Query: 346 FYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAF 405
           +YATN +R DL +TW++YE  V+ P                                  F
Sbjct: 385 YYATNPNRIDLVATWRFYESVVSFPF---------------------------------F 411

Query: 406 RKDPPPEPSPSQKVSLKDRV-FSSPRGVAAKGKGSPQAQTVRRSPSADQSLEDSPSKVPK 464
           RK+   E + SQK+ L DRV  S+PRG   KGK          +P    ++E+SPSK PK
Sbjct: 412 RKEQL-EAASSQKLGLLDRVRLSNPRGSNTKGK--------LFTPLNVDAIEESPSKEPK 462

Query: 465 SWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTEDLTPGLKVSIRA 524
                ++ R R AFR+K  A  Q+SE+A   G+ + +D+    +F  ED+ P LK +IRA
Sbjct: 463 PVGLNNKERFRTAFRMKAYAFWQSSEDAGT-GDPMAEDRGYGNDFPIEDMIPTLKAAIRA 521

Query: 525 VCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITDK 584
           V +++F + K+KFKE+LRPYDV DVIEQYSAGHLDMLSRIK LQ+R+D I   GP  T K
Sbjct: 522 VRILQFRLYKKKFKETLRPYDVKDVIEQYSAGHLDMLSRIKYLQTRIDMIFTPGPPSTPK 581

Query: 585 DR--TKG-------------------PAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLV 623
            +   KG                   P+ +E+ ED SMMG+  KVE+QV  M KKLDFLV
Sbjct: 582 HKKSQKGSAFTFPSQQSPRNEPYVARPSTSEI-EDQSMMGKFVKVERQVQDMGKKLDFLV 640

Query: 624 NIYMQRMGIPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSSTGQKNF 683
           +++MQ M     +   Y+  K           ED     +R+  +  I+ + S TG    
Sbjct: 641 DMHMQHMERLQVQVTEYYPTKGTSSPAEAEKKED-----NRYSDLKTIICNYSETG---- 691

Query: 684 SAPPAAPPVQCPPST----------SWQPQSHPRQG------HGTSPVGDHGSLVRIPPP 727
              P  PP      T          +  P + PR G        T P      + R    
Sbjct: 692 ---PPEPPYSFHQVTIDKVSPYGFFAHDPVNLPRGGPSSGKVQATPPSSATTYVERPTVL 748

Query: 728 PAHERSLSAYGGGNRASMEFLRQEDTPGCRPPEGNLRDSDTSISIPSVDHEELERSFSGF 787
           P      S     ++A ++     D    R      RDSDT +S+ SV+HEELERS SGF
Sbjct: 749 PILTLLDSRVSCHSQADLQG-PYSDRISPRQRRSITRDSDTPLSLMSVNHEELERSPSGF 807

Query: 788 SISQSKENLDALNSCYAAVAPCAKVRPYIAEGESDTDSDLCTPCGPPPRSATGEGPFGDV 847
           SISQ +++     +     +   + + Y+AEGE+DTD+D  TP G  P S+TG+G   D 
Sbjct: 808 SISQDRDDYVFGPN---GGSSWMREKRYLAEGETDTDTDPFTPSGSMPLSSTGDG-ISDS 863

Query: 848 GWAGPRK 854
            W    K
Sbjct: 864 VWTPSNK 870


>gi|26638655 potassium voltage-gated channel KQT-like protein 4
           isoform b [Homo sapiens]
          Length = 641

 Score =  661 bits (1705), Expect = 0.0
 Identities = 355/652 (54%), Positives = 444/652 (68%), Gaps = 69/652 (10%)

Query: 44  GSEAPKRGSILSKPRAGGA-------GAG-----KPPKRNAFYRKLQNFLYNVLERPRGW 91
           G  +P+R  +L  P   GA       G+G     +    +  YR+LQN++YNVLERPRGW
Sbjct: 38  GGGSPRRLGLLGSPLPPGAPLPGPGSGSGSACGQRSSAAHKRYRRLQNWVYNVLERPRGW 97

Query: 92  AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCC 151
           AF+YH ++FLLVFSCLVLSV STI+E+++ +   L ILE V IVVFG+EY VR+W+AGCC
Sbjct: 98  AFVYHVFIFLLVFSCLVLSVLSTIQEHQELANECLLILEFVMIVVFGLEYIVRVWSAGCC 157

Query: 152 CRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRM 211
           CRYRGW+GR +FARKPFCVID +V +AS+AV+AAG+QGN+FATSALRS+RFLQILRM+RM
Sbjct: 158 CRYRGWQGRFRFARKPFCVIDFIVFVASVAVIAAGTQGNIFATSALRSMRFLQILRMVRM 217

Query: 212 DRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGENDHFDTYADALWWG 271
           DRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI ASFLVYLAEK  N  F +YAD+LWWG
Sbjct: 218 DRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFASFLVYLAEKDANSDFSSYADSLWWG 277

Query: 272 LITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEK 331
            ITLTTIGYGDK P TW GR+LAA F L+G+SFFALPAGILGSGFALKVQEQHRQKHFEK
Sbjct: 278 TITLTTIGYGDKTPHTWLGRVLAAGFALLGISFFALPAGILGSGFALKVQEQHRQKHFEK 337

Query: 332 RRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQL 391
           RR PAA LIQ+AWR Y+T++SR  L +TW YY+  +                        
Sbjct: 338 RRMPAANLIQAAWRLYSTDMSRAYLTATWYYYDSIL------------------------ 373

Query: 392 ELLRNLKSKSGLAFRKDPPPEPSPSQKVSLKDRV-FSSPRGVAAKGKGSPQAQTVRRSPS 450
                                PS S ++ +KDR+   S +      K      T+  SPS
Sbjct: 374 ---------------------PSFSSRMGIKDRIRMGSSQRRTGPSKQHLAPPTMPTSPS 412

Query: 451 ADQSLE-DSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEF 509
           ++Q  E  SP+KV KSWSF DR+R R + R+K    R ++E+A  P E++ ++KS  CE 
Sbjct: 413 SEQVGEATSPTKVQKSWSFNDRTRFRASLRLK---PRTSAEDA--PSEEVAEEKSYQCEL 467

Query: 510 VTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQS 569
             +D+ P +K  IR++ +++FLV+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ+
Sbjct: 468 TVDDIMPAVKTVIRSIRILKFLVAKRKFKETLRPYDVKDVIEQYSAGHLDMLGRIKSLQT 527

Query: 570 RVDQIVGRGPA--ITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYM 627
           RVDQIVGRGP      +   KGP++AE+ ++ SMMGR+ KVEKQV S+E KLD L+  Y 
Sbjct: 528 RVDQIVGRGPGDRKAREKGDKGPSDAEVVDEISMMGRVVKVEKQVQSIEHKLDLLLGFYS 587

Query: 628 Q--RMGIPPTETEAYFGAKEPEPAPPYHSPEDSREHVDRHGCIVKIVRSSSS 677
           +  R G   +         +P+    YHSP D  E +      + I RS S+
Sbjct: 588 RCLRSGTSASLGAVQVPLFDPDITSDYHSPVD-HEDISVSAQTLSISRSVST 638


>gi|236462242 potassium voltage-gated channel, KQT-like subfamily,
           member 5 isoform 5 [Homo sapiens]
          Length = 822

 Score =  474 bits (1219), Expect = e-133
 Identities = 241/368 (65%), Positives = 282/368 (76%), Gaps = 17/368 (4%)

Query: 34  STRDGALLIAGSEAPKRGSI---LSKPRAGGAGA-----GKPP--------KRNAFYRKL 77
           + R   LL+ G+ A   G     L + R G  GA     GKP         +RN  YR++
Sbjct: 52  AARGDGLLLLGTRAATLGGGGGGLRESRRGKQGARMSLLGKPLSYTSSQSCRRNVKYRRV 111

Query: 78  QNFLYNVLERPRGWAFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVF 137
           QN+LYNVLERPRGWAFIYHA+VFLLVF CL+LSVFSTI E+ K +   L ILE V IVVF
Sbjct: 112 QNYLYNVLERPRGWAFIYHAFVFLLVFGCLILSVFSTIPEHTKLASSCLLILEFVMIVVF 171

Query: 138 GVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSAL 197
           G+E+ +RIW+AGCCCRYRGW+GRL+FARKPFCVID +VLIASIAV++A +QGN+FATSAL
Sbjct: 172 GLEFIIRIWSAGCCCRYRGWQGRLRFARKPFCVIDTIVLIASIAVVSAKTQGNIFATSAL 231

Query: 198 RSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGE 257
           RSLRFLQILRM+RMDRRGGTWKLLGSVVYAHSKEL+TAWYIGFL LI +SFLVYL EK  
Sbjct: 232 RSLRFLQILRMVRMDRRGGTWKLLGSVVYAHSKELITAWYIGFLVLIFSSFLVYLVEKDA 291

Query: 258 NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFA 317
           N  F TYADALWWG ITLTTIGYGDK P TW GRLL+A F L+G+SFFALPAGILGSGFA
Sbjct: 292 NKEFSTYADALWWGTITLTTIGYGDKTPLTWLGRLLSAGFALLGISFFALPAGILGSGFA 351

Query: 318 LKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQ 377
           LKVQEQHRQKHFEKRRNPAA LIQ  WR YA +     + +TW+ + + +     + + Q
Sbjct: 352 LKVQEQHRQKHFEKRRNPAANLIQCVWRSYAADEKSVSI-ATWKPHLKALHTCSPTKKEQ 410

Query: 378 TYGASRLI 385
              +SR++
Sbjct: 411 GEASSRIM 418



 Score =  138 bits (347), Expect = 2e-32
 Identities = 85/168 (50%), Positives = 106/168 (63%), Gaps = 8/168 (4%)

Query: 527 VMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVDQIVGRGPAITD-KD 585
           +M+F V+KRKFKE+LRPYDV DVIEQYSAGHLDML RIKSLQ+RVDQI+G+G   +D K 
Sbjct: 417 IMKFHVAKRKFKETLRPYDVKDVIEQYSAGHLDMLCRIKSLQTRVDQILGKGQITSDKKS 476

Query: 586 RTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQ--RMGIPPTETEAYFGA 643
           R K  AE E  +D SM+GR+ KVEKQV S+E KLD L++IY Q  R G       A F  
Sbjct: 477 REKITAEHETTDDLSMLGRVVKVEKQVQSIESKLDCLLDIYQQVLRKGSASALALASFQI 536

Query: 644 K--EPEPAPPYHSPEDSRE---HVDRHGCIVKIVRSSSSTGQKNFSAP 686
              E E    Y SP DS++        GC+ +   ++ S G +    P
Sbjct: 537 PPFECEQTSDYQSPVDSKDLSGSAQNSGCLSRSTSANISRGLQFILTP 584


>gi|32479527 potassium voltage-gated channel, KQT-like subfamily,
           member 1 isoform 1 [Homo sapiens]
          Length = 676

 Score =  400 bits (1029), Expect = e-111
 Identities = 241/615 (39%), Positives = 355/615 (57%), Gaps = 67/615 (10%)

Query: 29  PGAPDSTRDGALLIAGSEAPKRGSILSKPRAGGAGAGKPPKRNAFYRKLQNFLYNVLERP 88
           P  P S    A     S+   R  +   PR       +P         +Q  +YN LERP
Sbjct: 61  PAPPASPAAPAAPPVASDLGPRPPVSLDPRVSIYSTRRPVLARTH---VQGRVYNFLERP 117

Query: 89  RGW-AFIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWA 147
            GW  F+YH  VFL+V  CL+ SV STI++Y   + G L+ +EIV +V FG EY VR+W+
Sbjct: 118 TGWKCFVYHFAVFLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWS 177

Query: 148 AGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILR 207
           AGC  +Y G  GRL+FARKP  +ID++V++AS+ VL  GS+G VFATSA+R +RFLQILR
Sbjct: 178 AGCRSKYVGLWGRLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILR 237

Query: 208 MIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGEND-----HFD 262
           M+ +DR+GGTW+LLGSVV+ H +EL+T  YIGFL LI +S+ VYLAEK   +      F 
Sbjct: 238 MLHVDRQGGTWRLLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFG 297

Query: 263 TYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQE 322
           +YADALWWG++T+TTIGYGDK PQTW G+ +A+ F++  +SFFALPAGILGSGFALKVQ+
Sbjct: 298 SYADALWWGVVTVTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQ 357

Query: 323 QHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGAS 382
           + RQKHF ++   AA LIQ+AWR YA   +     STW+ Y R           +   + 
Sbjct: 358 KQRQKHFNRQIPAAASLIQTAWRCYA---AENPDSSTWKIYIR-----------KAPRSH 403

Query: 383 RLIPPLNQLELLRNLKSKSGLAFRKDPPPEPSPSQKVSLKDRVFSSPRGVAAKGKGSPQA 442
            L+ P  + +    +K K    F+ D     +P +K+     +   P         S   
Sbjct: 404 TLLSPSPKPKKSVVVKKKK---FKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDG 460

Query: 443 --QTVRRSPSADQSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIV 500
              +VR+SP+    LE S     ++ SF                    +E+  L GE ++
Sbjct: 461 YDSSVRKSPTL---LEVSMPHFMRTNSF--------------------AEDLDLEGETLL 497

Query: 501 DDKSCPCEFVTEDLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDM 560
                P   +++ L    + +I+ +  M++ V+K+KF+++ +PYDV DVIEQYS GHL++
Sbjct: 498 ----TPITHISQ-LREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNL 552

Query: 561 LSRIKSLQSRVDQIVGRGP---AITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEK 617
           + RIK LQ R+DQ +G+     ++++K + +G          ++  RL +VE +V  +++
Sbjct: 553 MVRIKELQRRLDQSIGKPSLFISVSEKSKDRG--------SNTIGARLNRVEDKVTQLDQ 604

Query: 618 KLDFLVNIYMQRMGI 632
           +L  + ++  Q + +
Sbjct: 605 RLALITDMLHQLLSL 619


>gi|32479525 potassium voltage-gated channel, KQT-like subfamily,
           member 1 isoform 2 [Homo sapiens]
          Length = 549

 Score =  375 bits (963), Expect = e-104
 Identities = 219/543 (40%), Positives = 327/543 (60%), Gaps = 63/543 (11%)

Query: 100 FLLVFSCLVLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
           FL+V  CL+ SV STI++Y   + G L+ +EIV +V FG EY VR+W+AGC  +Y G  G
Sbjct: 3   FLIVLVCLIFSVLSTIEQYAALATGTLFWMEIVLVVFFGTEYVVRLWSAGCRSKYVGLWG 62

Query: 160 RLKFARKPFCVIDIMVLIASIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWK 219
           RL+FARKP  +ID++V++AS+ VL  GS+G VFATSA+R +RFLQILRM+ +DR+GGTW+
Sbjct: 63  RLRFARKPISIIDLIVVVASMVVLCVGSKGQVFATSAIRGIRFLQILRMLHVDRQGGTWR 122

Query: 220 LLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEKGEND-----HFDTYADALWWGLIT 274
           LLGSVV+ H +EL+T  YIGFL LI +S+ VYLAEK   +      F +YADALWWG++T
Sbjct: 123 LLGSVVFIHRQELITTLYIGFLGLIFSSYFVYLAEKDAVNESGRVEFGSYADALWWGVVT 182

Query: 275 LTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRN 334
           +TTIGYGDK PQTW G+ +A+ F++  +SFFALPAGILGSGFALKVQ++ RQKHF ++  
Sbjct: 183 VTTIGYGDKVPQTWVGKTIASCFSVFAISFFALPAGILGSGFALKVQQKQRQKHFNRQIP 242

Query: 335 PAAGLIQSAWRFYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQLELL 394
            AA LIQ+AWR YA   +     STW+ Y R           +   +  L+ P  + +  
Sbjct: 243 AAASLIQTAWRCYA---AENPDSSTWKIYIR-----------KAPRSHTLLSPSPKPKKS 288

Query: 395 RNLKSKSGLAFRKDPPPEPSPSQKVSLKDRVFSSPRGVAAKGKGSPQA--QTVRRSPSAD 452
             +K K    F+ D     +P +K+     +   P         S      +VR+SP+  
Sbjct: 289 VVVKKKK---FKLDKDNGVTPGEKMLTVPHITCDPPEERRLDHFSVDGYDSSVRKSPTL- 344

Query: 453 QSLEDSPSKVPKSWSFGDRSRARQAFRIKGAASRQNSEEASLPGEDIVDDKSCPCEFVTE 512
             LE S     ++ SF                    +E+  L GE ++     P   +++
Sbjct: 345 --LEVSMPHFMRTNSF--------------------AEDLDLEGETLL----TPITHISQ 378

Query: 513 DLTPGLKVSIRAVCVMRFLVSKRKFKESLRPYDVMDVIEQYSAGHLDMLSRIKSLQSRVD 572
            L    + +I+ +  M++ V+K+KF+++ +PYDV DVIEQYS GHL+++ RIK LQ R+D
Sbjct: 379 -LREHHRATIKVIRRMQYFVAKKKFQQARKPYDVRDVIEQYSQGHLNLMVRIKELQRRLD 437

Query: 573 QIVGRGP---AITDKDRTKGPAEAELPEDPSMMGRLGKVEKQVLSMEKKLDFLVNIYMQR 629
           Q +G+     ++++K + +G          ++  RL +VE +V  ++++L  + ++  Q 
Sbjct: 438 QSIGKPSLFISVSEKSKDRG--------SNTIGARLNRVEDKVTQLDQRLALITDMLHQL 489

Query: 630 MGI 632
           + +
Sbjct: 490 LSL 492


>gi|21217561 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2a [Homo sapiens]
          Length = 613

 Score =  104 bits (260), Expect = 3e-22
 Identities = 77/292 (26%), Positives = 137/292 (46%), Gaps = 44/292 (15%)

Query: 62  AGAGKPPKRNAFYRKLQNFLYNVLERP---RGWAFIYHAYVFLLVFS----CL------- 107
           AG G P  ++  +R+LQ  ++ + E P   R   FI  A +F ++ S    CL       
Sbjct: 196 AGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFN 255

Query: 108 --------VLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
                   V++  S + +YE  ++ AL  +E V +V F  E+ VRI  +           
Sbjct: 256 IVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSP---------N 306

Query: 160 RLKFARKPFCVIDIMVLIA---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGG 216
           +L+F +    +ID + ++     + +    S+        LR +RF++ILR+ ++ R   
Sbjct: 307 KLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFV 366

Query: 217 TWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEK----------GENDHFDTYAD 266
             ++LG  + A + E +       L +++ + ++Y AE+           E+  F     
Sbjct: 367 GLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPI 426

Query: 267 ALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFAL 318
             WW ++T+TT+GYGD YPQTW+G L+ A   L GV   A+P  ++ + F +
Sbjct: 427 GFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478


>gi|21217563 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2b [Homo sapiens]
          Length = 638

 Score =  104 bits (260), Expect = 3e-22
 Identities = 77/292 (26%), Positives = 137/292 (46%), Gaps = 44/292 (15%)

Query: 62  AGAGKPPKRNAFYRKLQNFLYNVLERP---RGWAFIYHAYVFLLVFS----CL------- 107
           AG G P  ++  +R+LQ  ++ + E P   R   FI  A +F ++ S    CL       
Sbjct: 196 AGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFN 255

Query: 108 --------VLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
                   V++  S + +YE  ++ AL  +E V +V F  E+ VRI  +           
Sbjct: 256 IVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSP---------N 306

Query: 160 RLKFARKPFCVIDIMVLIA---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGG 216
           +L+F +    +ID + ++     + +    S+        LR +RF++ILR+ ++ R   
Sbjct: 307 KLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFV 366

Query: 217 TWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEK----------GENDHFDTYAD 266
             ++LG  + A + E +       L +++ + ++Y AE+           E+  F     
Sbjct: 367 GLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPI 426

Query: 267 ALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFAL 318
             WW ++T+TT+GYGD YPQTW+G L+ A   L GV   A+P  ++ + F +
Sbjct: 427 GFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478


>gi|24497458 Shaw-related voltage-gated potassium channel protein 2
           isoform KV3.2c [Homo sapiens]
          Length = 558

 Score =  104 bits (260), Expect = 3e-22
 Identities = 77/292 (26%), Positives = 137/292 (46%), Gaps = 44/292 (15%)

Query: 62  AGAGKPPKRNAFYRKLQNFLYNVLERP---RGWAFIYHAYVFLLVFS----CL------- 107
           AG G P  ++  +R+LQ  ++ + E P   R   FI  A +F ++ S    CL       
Sbjct: 196 AGLGGPDGKSGRWRRLQPRMWALFEDPYSSRAARFIAFASLFFILVSITTFCLETHEAFN 255

Query: 108 --------VLSVFSTIKEYEKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRG 159
                   V++  S + +YE  ++ AL  +E V +V F  E+ VRI  +           
Sbjct: 256 IVKNKTEPVINGTSVVLQYEIETDPALTYVEGVCVVWFTFEFLVRIVFSP---------N 306

Query: 160 RLKFARKPFCVIDIMVLIA---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGG 216
           +L+F +    +ID + ++     + +    S+        LR +RF++ILR+ ++ R   
Sbjct: 307 KLEFIKNLLNIIDFVAILPFYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFV 366

Query: 217 TWKLLGSVVYAHSKELVTAWYIGFLCLILASFLVYLAEK----------GENDHFDTYAD 266
             ++LG  + A + E +       L +++ + ++Y AE+           E+  F     
Sbjct: 367 GLRVLGHTLRASTNEFLLLIIFLALGVLIFATMIYYAERVGAQPNDPSASEHTQFKNIPI 426

Query: 267 ALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFFALPAGILGSGFAL 318
             WW ++T+TT+GYGD YPQTW+G L+ A   L GV   A+P  ++ + F +
Sbjct: 427 GFWWAVVTMTTLGYGDMYPQTWSGMLVGALCALAGVLTIAMPVPVIVNNFGM 478


>gi|119395748 potassium voltage-gated channel subfamily A member 1
           [Homo sapiens]
          Length = 495

 Score = 94.7 bits (234), Expect = 3e-19
 Identities = 61/199 (30%), Positives = 99/199 (49%), Gaps = 18/199 (9%)

Query: 127 YILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAA- 185
           +I+E + I+ F  E  VR +A            +  F +     IDI+ +I     L   
Sbjct: 222 FIVETLCIIWFSFELVVRFFACP---------SKTDFFKNIMNFIDIVAIIPYFITLGTE 272

Query: 186 -----GSQGNVFATSA--LRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYI 238
                G+Q    ATS   LR +R +++ R+ ++ R     ++LG  + A  +EL    + 
Sbjct: 273 IAEQEGNQKGEQATSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFF 332

Query: 239 GFLCLILASFLVYLAEKGEND-HFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATF 297
            F+ +IL S  VY AE  E + HF +  DA WW ++++TT+GYGD YP T  G+++ +  
Sbjct: 333 LFIGVILFSSAVYFAEAEEAESHFSSIPDAFWWAVVSMTTVGYGDMYPVTIGGKIVGSLC 392

Query: 298 TLIGVSFFALPAGILGSGF 316
            + GV   ALP  ++ S F
Sbjct: 393 AIAGVLTIALPVPVIVSNF 411


>gi|88758565 potassium voltage-gated channel, shaker-related
           subfamily, member 3 [Homo sapiens]
          Length = 575

 Score = 94.0 bits (232), Expect = 5e-19
 Identities = 58/197 (29%), Positives = 99/197 (50%), Gaps = 16/197 (8%)

Query: 127 YILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLA-- 184
           +++E + I+ F  E  VR +A            +  F+R    +IDI+ +I     L   
Sbjct: 296 FVVETLCIIWFSFELLVRFFACP---------SKATFSRNIMNLIDIVAIIPYFITLGTE 346

Query: 185 -AGSQGN---VFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGF 240
            A  QGN     + + LR +R +++ R+ ++ R     ++LG  + A  +EL    +  F
Sbjct: 347 LAERQGNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLF 406

Query: 241 LCLILASFLVYLAEKGE-NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTL 299
           + +IL S  VY AE  +    F +  DA WW ++T+TT+GYGD +P T  G+++ +   +
Sbjct: 407 IGVILFSSAVYFAEADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAI 466

Query: 300 IGVSFFALPAGILGSGF 316
            GV   ALP  ++ S F
Sbjct: 467 AGVLTIALPVPVIVSNF 483


>gi|4504817 potassium voltage-gated channel, shaker-related
           subfamily, member 4 [Homo sapiens]
          Length = 653

 Score = 94.0 bits (232), Expect = 5e-19
 Identities = 59/201 (29%), Positives = 97/201 (48%), Gaps = 20/201 (9%)

Query: 127 YILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLAA- 185
           +I+E V IV F  E+ VR +A            +  F +    +IDI+ ++     L   
Sbjct: 372 FIVETVCIVWFSFEFVVRCFACP---------SQALFFKNIMNIIDIVSILPYFITLGTD 422

Query: 186 ---------GSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAW 236
                    G Q    + + LR +R +++ R+ ++ R     ++LG  + A  +EL    
Sbjct: 423 LAQQQGGGNGQQQQAMSFAILRIIRLVRVFRIFKLSRHSKGLQILGHTLRASMRELGLLI 482

Query: 237 YIGFLCLILASFLVYLAEKGE-NDHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAA 295
           +  F+ +IL S  VY AE  E   HF +  DA WW ++T+TT+GYGD  P T  G+++ +
Sbjct: 483 FFLFIGVILFSSAVYFAEADEPTTHFQSIPDAFWWAVVTMTTVGYGDMKPITVGGKIVGS 542

Query: 296 TFTLIGVSFFALPAGILGSGF 316
              + GV   ALP  ++ S F
Sbjct: 543 LCAIAGVLTIALPVPVIVSNF 563


>gi|4826784 potassium voltage-gated channel, Shab-related subfamily,
           member 1 [Homo sapiens]
          Length = 858

 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 73/268 (27%), Positives = 132/268 (49%), Gaps = 24/268 (8%)

Query: 81  LYNVLERPRGWA---FIYHAYVFLLVFSCLVLSV-----FSTIKEYEKSSEGA-LYILEI 131
           L+++LE+P        +    +  +V S + LS+       ++ E+ +S++   L  +E 
Sbjct: 175 LWDLLEKPNSSVAAKILAIISIMFIVLSTIALSLNTLPELQSLDEFGQSTDNPQLAHVEA 234

Query: 132 VTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIAS-IAVLAAGSQGN 190
           V I  F +EY +R  ++      + W    KF + P   ID++ ++   + +    S  +
Sbjct: 235 VCIAWFTMEYLLRFLSSP-----KKW----KFFKGPLNAIDLLAILPYYVTIFLTESNKS 285

Query: 191 VFATSALRSL----RFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLILA 246
           V     +R +    R ++ILR++++ R     + LG  +     EL        + +++ 
Sbjct: 286 VLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMIF 345

Query: 247 SFLVYLAEKGEND-HFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSFF 305
           S LV+ AEK E+D  F +   + WW  IT+TT+GYGD YP+T  G+++     + GV   
Sbjct: 346 SSLVFFAEKDEDDTKFKSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLVI 405

Query: 306 ALPAGILGSGFALKVQEQHRQKHFEKRR 333
           ALP  I+ + F+   +EQ RQ+   KRR
Sbjct: 406 ALPIPIIVNNFSEFYKEQKRQEKAIKRR 433


>gi|163792201 Shaw-related voltage-gated potassium channel protein 1
           isoform A [Homo sapiens]
          Length = 585

 Score = 92.4 bits (228), Expect = 2e-18
 Identities = 70/298 (23%), Positives = 131/298 (43%), Gaps = 43/298 (14%)

Query: 119 EKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA 178
           E  +E  L  +E V +V F  E+ +R+              +++F +    +ID + ++ 
Sbjct: 238 EAETEAFLTYIEGVCVVWFTFEFLMRVIFCP---------NKVEFIKNSLNIIDFVAILP 288

Query: 179 ---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
               + +    S+        LR +RF++ILR+ ++ R     ++LG  + A + E +  
Sbjct: 289 FYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 348

Query: 236 WYIGFLCLILASFLVYLAEK----------GENDHFDTYADALWWGLITLTTIGYGDKYP 285
                L +++ + ++Y AE+           E+ HF       WW ++T+TT+GYGD YP
Sbjct: 349 IIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYP 408

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWR 345
           QTW+G L+ A   L GV   A+P  ++ + F +       ++   K++            
Sbjct: 409 QTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKK----------- 457

Query: 346 FYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGL 403
               ++ R     +  Y +  V  P +S+Q+ T        PL Q E+L   ++ S L
Sbjct: 458 ---KHIPRPPQLGSPNYCKSVVNSPHHSTQSDTC-------PLAQEEILEINRADSKL 505


>gi|27436974 potassium voltage-gated channel, Shab-related
           subfamily, member 2 [Homo sapiens]
          Length = 911

 Score = 91.7 bits (226), Expect = 3e-18
 Identities = 73/269 (27%), Positives = 131/269 (48%), Gaps = 26/269 (9%)

Query: 81  LYNVLERPRGWA---FIYHAYVFLLVFSCLVLSVFSTIKEYEKSSEGA-------LYILE 130
           L+++LE+P        +    +  +V S + LS+ +T+ E +++ E         L  +E
Sbjct: 179 LWDLLEKPNSSVAAKILAIVSILFIVLSTIALSL-NTLPELQETDEFGQLNDNRQLAHVE 237

Query: 131 IVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIAS-IAVLAAGSQG 189
            V I  F +EY +R  ++           + KF + P  VID++ ++   + +    S  
Sbjct: 238 AVCIAWFTMEYLLRFLSSP---------NKWKFFKGPLNVIDLLAILPYYVTIFLTESNK 288

Query: 190 NVFATSALRSL----RFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLIL 245
           +V     +R +    R ++ILR++++ R     + LG  +     EL        + +++
Sbjct: 289 SVLQFQNVRRVVQIFRIMRILRILKLARHSTGLQSLGFTLRRSYNELGLLILFLAMGIMI 348

Query: 246 ASFLVYLAEKGEN-DHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVSF 304
            S LV+ AEK E+   F +   + WW  IT+TT+GYGD YP+T  G+++     + GV  
Sbjct: 349 FSSLVFFAEKDEDATKFTSIPASFWWATITMTTVGYGDIYPKTLLGKIVGGLCCIAGVLV 408

Query: 305 FALPAGILGSGFALKVQEQHRQKHFEKRR 333
            ALP  I+ + F+   +EQ RQ+   KRR
Sbjct: 409 IALPIPIIVNNFSEFYKEQKRQEKAIKRR 437


>gi|4826786 Shaw-related voltage-gated potassium channel protein 1
           isoform B [Homo sapiens]
          Length = 511

 Score = 91.7 bits (226), Expect = 3e-18
 Identities = 68/289 (23%), Positives = 127/289 (43%), Gaps = 43/289 (14%)

Query: 119 EKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA 178
           E  +E  L  +E V +V F  E+ +R+              +++F +    +ID + ++ 
Sbjct: 238 EAETEAFLTYIEGVCVVWFTFEFLMRVIFCP---------NKVEFIKNSLNIIDFVAILP 288

Query: 179 ---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
               + +    S+        LR +RF++ILR+ ++ R     ++LG  + A + E +  
Sbjct: 289 FYLEVGLSGLSSKAAKDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 348

Query: 236 WYIGFLCLILASFLVYLAEK----------GENDHFDTYADALWWGLITLTTIGYGDKYP 285
                L +++ + ++Y AE+           E+ HF       WW ++T+TT+GYGD YP
Sbjct: 349 IIFLALGVLIFATMIYYAERIGAQPNDPSASEHTHFKNIPIGFWWAVVTMTTLGYGDMYP 408

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWR 345
           QTW+G L+ A   L GV   A+P  ++ + F +       ++   K++            
Sbjct: 409 QTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKKK----------- 457

Query: 346 FYATNLSRTDLHSTWQYYERTVTVPMYSSQTQTYGASRLIPPLNQLELL 394
               ++ R     +  Y +  V  P +S+Q+ T        PL Q E+L
Sbjct: 458 ---KHIPRPPQLGSPNYCKSVVNSPHHSTQSDTC-------PLAQEEIL 496


>gi|27436984 potassium voltage-gated channel, Shal-related
           subfamily, member 3 isoform 1 [Homo sapiens]
          Length = 655

 Score = 90.9 bits (224), Expect = 5e-18
 Identities = 68/287 (23%), Positives = 134/287 (46%), Gaps = 16/287 (5%)

Query: 125 ALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVLA 184
           A + L+   +++F VEY +R++AA           R +F R    +ID++ ++     L 
Sbjct: 225 AFFCLDTACVMIFTVEYLLRLFAAP---------SRYRFIRSVMSIIDVVAIMPYYIGLV 275

Query: 185 AGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTAWYIGFLCLI 244
             +  +V  + A  +LR  ++ R+ +  R     ++LG  + + + EL    +   + +I
Sbjct: 276 MTNNEDV--SGAFVTLRVFRVFRIFKFSRHSQGLRILGYTLKSCASELGFLLFSLTMAII 333

Query: 245 LASFLVYLAEKGEN-DHFDTYADALWWGLITLTTIGYGDKYPQTWNGRLLAATFTLIGVS 303
           + + +++ AEKG +   F +   + W+ ++T+TT+GYGD  P+T  G++  +  +L GV 
Sbjct: 334 IFATVMFYAEKGSSASKFTSIPASFWYTIVTMTTLGYGDMVPKTIAGKIFGSICSLSGVL 393

Query: 304 FFALPAGILGSGFALKVQEQHRQKHFEKRRNPAAGLIQSAWRFYATNLSRTDLHSTWQYY 363
             ALP  ++ S F+   +  H+ +  +KRR      + +  R   T  S   LHS     
Sbjct: 394 VIALPVPVIVSNFS---RIYHQNQRADKRRAQKKARL-ARIRVAKTGSSNAYLHSKRNGL 449

Query: 364 ERTVTVPMYSSQTQTYGASRLIPPLNQLELLRNLKSKSGLAFRKDPP 410
                    + + +  G +  +       LL  L+  +GL++  D P
Sbjct: 450 LNEALELTGTPEEEHMGKTTSLIESQHHHLLHCLEKTTGLSYLVDDP 496


>gi|88758576 Shaw-related voltage-gated potassium channel protein 4
           isoform c [Homo sapiens]
          Length = 626

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 61/228 (26%), Positives = 108/228 (47%), Gaps = 22/228 (9%)

Query: 119 EKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA 178
           E  +E  L  +E V ++ F +E+ VRI     CC        L F +    +ID + ++ 
Sbjct: 274 EVETEPILTYIEGVCVLWFTLEFLVRI----VCCP-----DTLDFVKNLLNIIDFVAILP 324

Query: 179 ---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
               + +    S+        LR +RF++ILR+ ++ R     ++LG  + A + E +  
Sbjct: 325 FYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 384

Query: 236 WYIGFLCLILASFLVYLAEK--------GENDH--FDTYADALWWGLITLTTIGYGDKYP 285
                L +++ + ++Y AE+          NDH  F       WW ++T+TT+GYGD YP
Sbjct: 385 IIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYP 444

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRR 333
           +TW+G L+ A   L GV   A+P  ++ + F +       ++   K+R
Sbjct: 445 KTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492


>gi|24497462 Shaw-related voltage-gated potassium channel protein 4
           isoform a [Homo sapiens]
          Length = 635

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 61/228 (26%), Positives = 108/228 (47%), Gaps = 22/228 (9%)

Query: 119 EKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA 178
           E  +E  L  +E V ++ F +E+ VRI     CC        L F +    +ID + ++ 
Sbjct: 274 EVETEPILTYIEGVCVLWFTLEFLVRI----VCCP-----DTLDFVKNLLNIIDFVAILP 324

Query: 179 ---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
               + +    S+        LR +RF++ILR+ ++ R     ++LG  + A + E +  
Sbjct: 325 FYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 384

Query: 236 WYIGFLCLILASFLVYLAEK--------GENDH--FDTYADALWWGLITLTTIGYGDKYP 285
                L +++ + ++Y AE+          NDH  F       WW ++T+TT+GYGD YP
Sbjct: 385 IIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYP 444

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRR 333
           +TW+G L+ A   L GV   A+P  ++ + F +       ++   K+R
Sbjct: 445 KTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492


>gi|24497464 Shaw-related voltage-gated potassium channel protein 4
           isoform b [Homo sapiens]
          Length = 582

 Score = 89.7 bits (221), Expect = 1e-17
 Identities = 61/228 (26%), Positives = 108/228 (47%), Gaps = 22/228 (9%)

Query: 119 EKSSEGALYILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIA 178
           E  +E  L  +E V ++ F +E+ VRI     CC        L F +    +ID + ++ 
Sbjct: 274 EVETEPILTYIEGVCVLWFTLEFLVRI----VCCP-----DTLDFVKNLLNIIDFVAILP 324

Query: 179 ---SIAVLAAGSQGNVFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSKELVTA 235
               + +    S+        LR +RF++ILR+ ++ R     ++LG  + A + E +  
Sbjct: 325 FYLEVGLSGLSSKAARDVLGFLRVVRFVRILRIFKLTRHFVGLRVLGHTLRASTNEFLLL 384

Query: 236 WYIGFLCLILASFLVYLAEK--------GENDH--FDTYADALWWGLITLTTIGYGDKYP 285
                L +++ + ++Y AE+          NDH  F       WW ++T+TT+GYGD YP
Sbjct: 385 IIFLALGVLIFATMIYYAERIGARPSDPRGNDHTDFKNIPIGFWWAVVTMTTLGYGDMYP 444

Query: 286 QTWNGRLLAATFTLIGVSFFALPAGILGSGFALKVQEQHRQKHFEKRR 333
           +TW+G L+ A   L GV   A+P  ++ + F +       ++   K+R
Sbjct: 445 KTWSGMLVGALCALAGVLTIAMPVPVIVNNFGMYYSLAMAKQKLPKKR 492


>gi|4504821 potassium voltage-gated channel, shaker-related
           subfamily, member 6 [Homo sapiens]
          Length = 529

 Score = 89.0 bits (219), Expect = 2e-17
 Identities = 58/207 (28%), Positives = 98/207 (47%), Gaps = 26/207 (12%)

Query: 127 YILEIVTIVVFGVEYFVRIWAAGCCCRYRGWRGRLKFARKPFCVIDIMVLIASIAVL--- 183
           +++E + IV F  E  VR  A            +  F R    +ID++ +      L   
Sbjct: 264 FLVETLCIVWFTFELLVRFSACP---------SKPAFFRNIMNIIDLVAIFPYFITLGTE 314

Query: 184 ---------AAGSQGN----VFATSALRSLRFLQILRMIRMDRRGGTWKLLGSVVYAHSK 230
                    A+G  G       + + LR +R +++ R+ ++ R     ++LG  + A  +
Sbjct: 315 LVQQQEQQPASGGGGQNGQQAMSLAILRVIRLVRVFRIFKLSRHSKGLQILGKTLQASMR 374

Query: 231 ELVTAWYIGFLCLILASFLVYLAEKGENDH-FDTYADALWWGLITLTTIGYGDKYPQTWN 289
           EL    +  F+ +IL S  VY AE  ++D  F +  DA WW ++T+TT+GYGD YP T  
Sbjct: 375 ELGLLIFFLFIGVILFSSAVYFAEADDDDSLFPSIPDAFWWAVVTMTTVGYGDMYPMTVG 434

Query: 290 GRLLAATFTLIGVSFFALPAGILGSGF 316
           G+++ +   + GV   ALP  ++ S F
Sbjct: 435 GKIVGSLCAIAGVLTIALPVPVIVSNF 461


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.318    0.135    0.413 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 37,969,696
Number of Sequences: 37866
Number of extensions: 1986241
Number of successful extensions: 9297
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 94
Number of HSP's successfully gapped in prelim test: 144
Number of HSP's that attempted gapping in prelim test: 8722
Number of HSP's gapped (non-prelim): 608
length of query: 854
length of database: 18,247,518
effective HSP length: 111
effective length of query: 743
effective length of database: 14,044,392
effective search space: 10434983256
effective search space used: 10434983256
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 66 (30.0 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.