BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|119703749 hydrocephalus inducing isoform a [Homo sapiens] (5120 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|119703749 hydrocephalus inducing isoform a [Homo sapiens] 1.029e+04 0.0 gi|46361983 hydrocephalus inducing isoform b [Homo sapiens] 2055 0.0 gi|90669228 deleted in lung and esophageal cancer 1 isoform DLEC... 118 1e-25 gi|90669194 deleted in lung and esophageal cancer 1 isoform DLEC... 118 1e-25 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 80 5e-14 gi|148746195 trichohyalin [Homo sapiens] 80 5e-14 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 75 2e-12 gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 74 4e-12 gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 74 4e-12 gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 72 1e-11 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 71 3e-11 gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 70 5e-11 gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 70 7e-11 gi|102467235 inner centromere protein antigens 135/155kDa isofor... 66 1e-09 gi|102467242 inner centromere protein antigens 135/155kDa isofor... 66 1e-09 gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] 65 1e-09 gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] 65 1e-09 gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] 65 2e-09 gi|78042577 MAP7 domain containing 1 [Homo sapiens] 65 2e-09 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 65 2e-09 gi|84043963 eukaryotic translation initiation factor 5B [Homo sa... 64 3e-09 gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 63 7e-09 gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 63 7e-09 gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 63 7e-09 gi|22758136 MAP7 domain containing 2 [Homo sapiens] 62 1e-08 gi|55741709 RNA binding motif protein 25 [Homo sapiens] 62 2e-08 gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sa... 61 3e-08 gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 60 4e-08 gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 60 4e-08 gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sap... 60 4e-08 >gi|119703749 hydrocephalus inducing isoform a [Homo sapiens] Length = 5120 Score = 1.029e+04 bits (26703), Expect = 0.0 Identities = 5120/5120 (100%), Positives = 5120/5120 (100%) Query: 1 MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE 60 MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE Sbjct: 1 MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE 60 Query: 61 QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL 120 QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL Sbjct: 61 QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL 120 Query: 121 ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC 180 ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC Sbjct: 121 ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC 180 Query: 181 VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP 240 VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP Sbjct: 181 VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP 240 Query: 241 FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD 300 FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD Sbjct: 241 FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD 300 Query: 301 KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE 360 KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE Sbjct: 301 KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE 360 Query: 361 TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE 420 TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE Sbjct: 361 TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE 420 Query: 421 ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC 480 ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC Sbjct: 421 ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC 480 Query: 481 YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE 540 YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE Sbjct: 481 YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE 540 Query: 541 FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK 600 FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK Sbjct: 541 FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK 600 Query: 601 LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT 660 LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT Sbjct: 601 LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT 660 Query: 661 LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL 720 LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL Sbjct: 661 LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL 720 Query: 721 QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV 780 QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV Sbjct: 721 QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV 780 Query: 781 YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ 840 YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ Sbjct: 781 YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ 840 Query: 841 AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS 900 AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS Sbjct: 841 AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS 900 Query: 901 GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG 960 GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG Sbjct: 901 GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG 960 Query: 961 RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPRIVKEKL 1020 RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPRIVKEKL Sbjct: 961 RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPRIVKEKL 1020 Query: 1021 VCHAIIGAQKGKSLVMAVNITCEFVAPLIQLSTKQLIYRLEKKPNSILKPDYQPLAIKNI 1080 VCHAIIGAQKGKSLVMAVNITCEFVAPLIQLSTKQLIYRLEKKPNSILKPDYQPLAIKNI Sbjct: 1021 VCHAIIGAQKGKSLVMAVNITCEFVAPLIQLSTKQLIYRLEKKPNSILKPDYQPLAIKNI 1080 Query: 1081 STLPVNLLLSTSGPFFICETDKSLLPATPEPIKLEIDEEKNLLIKFDPSYRNDLNNWVAE 1140 STLPVNLLLSTSGPFFICETDKSLLPATPEPIKLEIDEEKNLLIKFDPSYRNDLNNWVAE Sbjct: 1081 STLPVNLLLSTSGPFFICETDKSLLPATPEPIKLEIDEEKNLLIKFDPSYRNDLNNWVAE 1140 Query: 1141 EILAIKYVEHPQIDSLDLRGEVHYPNLSFETKELDFGCILNDTELIRYVTITNCSPLVVK 1200 EILAIKYVEHPQIDSLDLRGEVHYPNLSFETKELDFGCILNDTELIRYVTITNCSPLVVK Sbjct: 1141 EILAIKYVEHPQIDSLDLRGEVHYPNLSFETKELDFGCILNDTELIRYVTITNCSPLVVK 1200 Query: 1201 FRWFFLVNDEENQIRFVTLPKKPYSAPVSQMESIPATSEAASPPAILVTVESPEMDLNDF 1260 FRWFFLVNDEENQIRFVTLPKKPYSAPVSQMESIPATSEAASPPAILVTVESPEMDLNDF Sbjct: 1201 FRWFFLVNDEENQIRFVTLPKKPYSAPVSQMESIPATSEAASPPAILVTVESPEMDLNDF 1260 Query: 1261 VKTVLVDEDARPEEKELRKTKASSVISDVRCPFHGEERIYSSQSQVEDQESLQTCEQNEM 1320 VKTVLVDEDARPEEKELRKTKASSVISDVRCPFHGEERIYSSQSQVEDQESLQTCEQNEM Sbjct: 1261 VKTVLVDEDARPEEKELRKTKASSVISDVRCPFHGEERIYSSQSQVEDQESLQTCEQNEM 1320 Query: 1321 LSIGIEEVFDILPLFGVLQPHSSHQISFTFYGHANIIAQAKALCEVEEGPTYEITLKGEA 1380 LSIGIEEVFDILPLFGVLQPHSSHQISFTFYGHANIIAQAKALCEVEEGPTYEITLKGEA Sbjct: 1321 LSIGIEEVFDILPLFGVLQPHSSHQISFTFYGHANIIAQAKALCEVEEGPTYEITLKGEA 1380 Query: 1381 SLVNYSFDTKDIHYGLQLFDHVTEREITLTNMGKVGFEFKVLTDHQSSPDNLLPGVPLIL 1440 SLVNYSFDTKDIHYGLQLFDHVTEREITLTNMGKVGFEFKVLTDHQSSPDNLLPGVPLIL Sbjct: 1381 SLVNYSFDTKDIHYGLQLFDHVTEREITLTNMGKVGFEFKVLTDHQSSPDNLLPGVPLIL 1440 Query: 1441 PVSGFISSHQEQVLKVYYLPGVPEVFKRSFQIQIAHLDPENITLSGEGIFPQICLDLPRN 1500 PVSGFISSHQEQVLKVYYLPGVPEVFKRSFQIQIAHLDPENITLSGEGIFPQICLDLPRN Sbjct: 1441 PVSGFISSHQEQVLKVYYLPGVPEVFKRSFQIQIAHLDPENITLSGEGIFPQICLDLPRN 1500 Query: 1501 LTANEKYEMFLNQARKNTDKEYNKCEMLDHFDIITEEVPEDEPAEVSAHLQMEVERLIVQ 1560 LTANEKYEMFLNQARKNTDKEYNKCEMLDHFDIITEEVPEDEPAEVSAHLQMEVERLIVQ Sbjct: 1501 LTANEKYEMFLNQARKNTDKEYNKCEMLDHFDIITEEVPEDEPAEVSAHLQMEVERLIVQ 1560 Query: 1561 SYVLEHQKTTTPDPMDDPCFSHRSRRKLAKIQLPEYILDFGYIILGEVRTHIIKIINTSH 1620 SYVLEHQKTTTPDPMDDPCFSHRSRRKLAKIQLPEYILDFGYIILGEVRTHIIKIINTSH Sbjct: 1561 SYVLEHQKTTTPDPMDDPCFSHRSRRKLAKIQLPEYILDFGYIILGEVRTHIIKIINTSH 1620 Query: 1621 FPVSFHADKRVLHETGFSTELDRVKNLPHCETEIFEVRFDPQGANLPVGSKEVILPIKVV 1680 FPVSFHADKRVLHETGFSTELDRVKNLPHCETEIFEVRFDPQGANLPVGSKEVILPIKVV Sbjct: 1621 FPVSFHADKRVLHETGFSTELDRVKNLPHCETEIFEVRFDPQGANLPVGSKEVILPIKVV 1680 Query: 1681 GGPTVHICLQAKVTIPTMTLSRGKVDFATIQCGQCLVETIQLSNHLQVPCEWFVQSQKPV 1740 GGPTVHICLQAKVTIPTMTLSRGKVDFATIQCGQCLVETIQLSNHLQVPCEWFVQSQKPV Sbjct: 1681 GGPTVHICLQAKVTIPTMTLSRGKVDFATIQCGQCLVETIQLSNHLQVPCEWFVQSQKPV 1740 Query: 1741 DKLEKHMPKYLRQKLRAELKPKTRIFEIQPISGVLDPGEKSNVQVKFMPKEEKFYSQTLV 1800 DKLEKHMPKYLRQKLRAELKPKTRIFEIQPISGVLDPGEKSNVQVKFMPKEEKFYSQTLV Sbjct: 1741 DKLEKHMPKYLRQKLRAELKPKTRIFEIQPISGVLDPGEKSNVQVKFMPKEEKFYSQTLV 1800 Query: 1801 FQIAQSAQKLTLLARGQGLEPRLEFSPSVLDLGPLLLCAPGDEAEVIVKNPCNFPIEFYS 1860 FQIAQSAQKLTLLARGQGLEPRLEFSPSVLDLGPLLLCAPGDEAEVIVKNPCNFPIEFYS Sbjct: 1801 FQIAQSAQKLTLLARGQGLEPRLEFSPSVLDLGPLLLCAPGDEAEVIVKNPCNFPIEFYS 1860 Query: 1861 LEFDQQYLIEEKILRKLKGYDSYNTLLLPPRNPGEKLPPELYEYFKEIKKSKEEQMRAKY 1920 LEFDQQYLIEEKILRKLKGYDSYNTLLLPPRNPGEKLPPELYEYFKEIKKSKEEQMRAKY Sbjct: 1861 LEFDQQYLIEEKILRKLKGYDSYNTLLLPPRNPGEKLPPELYEYFKEIKKSKEEQMRAKY 1920 Query: 1921 LENLAQENEEEDITSSDQGTSNSTKRTSLSRGISVTSNLEEWHALLVESKTYLEEEEDEE 1980 LENLAQENEEEDITSSDQGTSNSTKRTSLSRGISVTSNLEEWHALLVESKTYLEEEEDEE Sbjct: 1921 LENLAQENEEEDITSSDQGTSNSTKRTSLSRGISVTSNLEEWHALLVESKTYLEEEEDEE 1980 Query: 1981 SLEKIIFQTDKLQSIDSHSMEEVGEVENNPVSKAIARHLGIDISAEGRLAKNRKGIAIII 2040 SLEKIIFQTDKLQSIDSHSMEEVGEVENNPVSKAIARHLGIDISAEGRLAKNRKGIAIII Sbjct: 1981 SLEKIIFQTDKLQSIDSHSMEEVGEVENNPVSKAIARHLGIDISAEGRLAKNRKGIAIII 2040 Query: 2041 HGTPLSGKSANAVSVAKYYNAACLSIDSIVLEAVANSNNIPGIRARELCIRAAIEQSVKE 2100 HGTPLSGKSANAVSVAKYYNAACLSIDSIVLEAVANSNNIPGIRARELCIRAAIEQSVKE Sbjct: 2041 HGTPLSGKSANAVSVAKYYNAACLSIDSIVLEAVANSNNIPGIRARELCIRAAIEQSVKE 2100 Query: 2101 GEEAAQEAAVGQNVIGQGRLSTDTLGKLASEMTLVAPEIKPGKSVRGSVVITKSKADSHG 2160 GEEAAQEAAVGQNVIGQGRLSTDTLGKLASEMTLVAPEIKPGKSVRGSVVITKSKADSHG Sbjct: 2101 GEEAAQEAAVGQNVIGQGRLSTDTLGKLASEMTLVAPEIKPGKSVRGSVVITKSKADSHG 2160 Query: 2161 SGSQKQHHSHQSETPQISSSPLPPGPIHRWLSVSPSVGGETGLMSCVLPDELLVQILAER 2220 SGSQKQHHSHQSETPQISSSPLPPGPIHRWLSVSPSVGGETGLMSCVLPDELLVQILAER Sbjct: 2161 SGSQKQHHSHQSETPQISSSPLPPGPIHRWLSVSPSVGGETGLMSCVLPDELLVQILAER 2220 Query: 2221 IQLSDCYRGVVFDGLDTLFAQNAAAALLCLLKAIGSREHIYILNMAQDYAAMKAQEKAKK 2280 IQLSDCYRGVVFDGLDTLFAQNAAAALLCLLKAIGSREHIYILNMAQDYAAMKAQEKAKK Sbjct: 2221 IQLSDCYRGVVFDGLDTLFAQNAAAALLCLLKAIGSREHIYILNMAQDYAAMKAQEKAKK 2280 Query: 2281 EQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEM 2340 EQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEM Sbjct: 2281 EQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEM 2340 Query: 2341 QEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIE 2400 QEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIE Sbjct: 2341 QEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIE 2400 Query: 2401 RKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYE 2460 RKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYE Sbjct: 2401 RKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYE 2460 Query: 2461 LTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERT 2520 LTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERT Sbjct: 2461 LTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERT 2520 Query: 2521 EKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSW 2580 EKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSW Sbjct: 2521 EKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSW 2580 Query: 2581 KQALESDKLPKGEQILDILGLGASGPPIPPPALFSIVSYPVKRPPLTMTDDLEHFVFVIP 2640 KQALESDKLPKGEQILDILGLGASGPPIPPPALFSIVSYPVKRPPLTMTDDLEHFVFVIP Sbjct: 2581 KQALESDKLPKGEQILDILGLGASGPPIPPPALFSIVSYPVKRPPLTMTDDLEHFVFVIP 2640 Query: 2641 PSEDISLDEKKEMEIESDFLATTNTTKAQEEQTSSSKGGKQKMKEKIDQVFEIQKDKRHM 2700 PSEDISLDEKKEMEIESDFLATTNTTKAQEEQTSSSKGGKQKMKEKIDQVFEIQKDKRHM Sbjct: 2641 PSEDISLDEKKEMEIESDFLATTNTTKAQEEQTSSSKGGKQKMKEKIDQVFEIQKDKRHM 2700 Query: 2701 ALNRKVLSGEPAGTISQLSDTDLDNFNGQHSQEKFTRLNHFRWIVPANGEVTLQVHFSSD 2760 ALNRKVLSGEPAGTISQLSDTDLDNFNGQHSQEKFTRLNHFRWIVPANGEVTLQVHFSSD Sbjct: 2701 ALNRKVLSGEPAGTISQLSDTDLDNFNGQHSQEKFTRLNHFRWIVPANGEVTLQVHFSSD 2760 Query: 2761 EFGNFDQTFNFEILGTCCQYQLYCRGICTYPYICQDPKVVFPQRKMDMKTNEVIFKKYVM 2820 EFGNFDQTFNFEILGTCCQYQLYCRGICTYPYICQDPKVVFPQRKMDMKTNEVIFKKYVM Sbjct: 2761 EFGNFDQTFNFEILGTCCQYQLYCRGICTYPYICQDPKVVFPQRKMDMKTNEVIFKKYVM 2820 Query: 2821 STETYYFGPLLCGKSRDKYKSSLFPGNMETLTILNTSLMVVEASFYFQNDVKANTYFLEP 2880 STETYYFGPLLCGKSRDKYKSSLFPGNMETLTILNTSLMVVEASFYFQNDVKANTYFLEP Sbjct: 2821 STETYYFGPLLCGKSRDKYKSSLFPGNMETLTILNTSLMVVEASFYFQNDVKANTYFLEP 2880 Query: 2881 NTMVLKPNEKQILNVWAYPTSVGVFEDSIVCCINDNPEPAIFQLSCQGIRPELELEPRQL 2940 NTMVLKPNEKQILNVWAYPTSVGVFEDSIVCCINDNPEPAIFQLSCQGIRPELELEPRQL Sbjct: 2881 NTMVLKPNEKQILNVWAYPTSVGVFEDSIVCCINDNPEPAIFQLSCQGIRPELELEPRQL 2940 Query: 2941 HFDRLLLHRQESRVVLLRNVTLLPVAWRITSLEHLGDDFTVSLMQGTIPPEAEYGLHLYF 3000 HFDRLLLHRQESRVVLLRNVTLLPVAWRITSLEHLGDDFTVSLMQGTIPPEAEYGLHLYF Sbjct: 2941 HFDRLLLHRQESRVVLLRNVTLLPVAWRITSLEHLGDDFTVSLMQGTIPPEAEYGLHLYF 3000 Query: 3001 QPTKPVNIKKAIRLEVLDAENLLGVVQIENIMVFAEAYDIALDITFPKGAEGGLDFGIVR 3060 QPTKPVNIKKAIRLEVLDAENLLGVVQIENIMVFAEAYDIALDITFPKGAEGGLDFGIVR Sbjct: 3001 QPTKPVNIKKAIRLEVLDAENLLGVVQIENIMVFAEAYDIALDITFPKGAEGGLDFGIVR 3060 Query: 3061 VTEEAKQPLQLKNRGKYEIAFSFSVDSVGISTPNINSMISVQPKKGSLTPTEKPTNVQVF 3120 VTEEAKQPLQLKNRGKYEIAFSFSVDSVGISTPNINSMISVQPKKGSLTPTEKPTNVQVF Sbjct: 3061 VTEEAKQPLQLKNRGKYEIAFSFSVDSVGISTPNINSMISVQPKKGSLTPTEKPTNVQVF 3120 Query: 3121 FHAKKEVKIEHQPVLRCQIIEPNISEGGEIIASIPIKFSANAVYSKYNITPSSVINFGAL 3180 FHAKKEVKIEHQPVLRCQIIEPNISEGGEIIASIPIKFSANAVYSKYNITPSSVINFGAL Sbjct: 3121 FHAKKEVKIEHQPVLRCQIIEPNISEGGEIIASIPIKFSANAVYSKYNITPSSVINFGAL 3180 Query: 3181 ICGTRKSTTFTIENQGVTDFKFALYKLTGESPIHQKKAASHVRHARSRESESFYKTGSSR 3240 ICGTRKSTTFTIENQGVTDFKFALYKLTGESPIHQKKAASHVRHARSRESESFYKTGSSR Sbjct: 3181 ICGTRKSTTFTIENQGVTDFKFALYKLTGESPIHQKKAASHVRHARSRESESFYKTGSSR 3240 Query: 3241 AAKFSDTIQKEVTTTGQARFAHGMFTVYPGFGSIPSGGQQVINVDCVADAMGKCEEFIAI 3300 AAKFSDTIQKEVTTTGQARFAHGMFTVYPGFGSIPSGGQQVINVDCVADAMGKCEEFIAI Sbjct: 3241 AAKFSDTIQKEVTTTGQARFAHGMFTVYPGFGSIPSGGQQVINVDCVADAMGKCEEFIAI 3300 Query: 3301 DISGRDPAVHPAGILYTLLAEACLPAFVTENNALIFEEHQICTSANLHHILQTIESGGLF 3360 DISGRDPAVHPAGILYTLLAEACLPAFVTENNALIFEEHQICTSANLHHILQTIESGGLF Sbjct: 3301 DISGRDPAVHPAGILYTLLAEACLPAFVTENNALIFEEHQICTSANLHHILQTIESGGLF 3360 Query: 3361 VEDENKFIFCNVLVGRQAKARFKISNVGKITCDVNIVVRPISNKPFARIVDIFEVEPSKM 3420 VEDENKFIFCNVLVGRQAKARFKISNVGKITCDVNIVVRPISNKPFARIVDIFEVEPSKM Sbjct: 3361 VEDENKFIFCNVLVGRQAKARFKISNVGKITCDVNIVVRPISNKPFARIVDIFEVEPSKM 3420 Query: 3421 CIASHSHAFATVSFTPQIMQNYQCIFEATLDGLPSTLAKSRGLVFDIAGEGNLPRVTVVR 3480 CIASHSHAFATVSFTPQIMQNYQCIFEATLDGLPSTLAKSRGLVFDIAGEGNLPRVTVVR Sbjct: 3421 CIASHSHAFATVSFTPQIMQNYQCIFEATLDGLPSTLAKSRGLVFDIAGEGNLPRVTVVR 3480 Query: 3481 PVLHNQYGNPLLLFKRLLLGHSEKLPLILKNNGVLPAQLHVDLQDELGVFSLKGRPTTAY 3540 PVLHNQYGNPLLLFKRLLLGHSEKLPLILKNNGVLPAQLHVDLQDELGVFSLKGRPTTAY Sbjct: 3481 PVLHNQYGNPLLLFKRLLLGHSEKLPLILKNNGVLPAQLHVDLQDELGVFSLKGRPTTAY 3540 Query: 3541 IYITEENKPHVKAKKAHTASLVVSPGDTAEFDVVFHSQKVGRMRGIIHLSVINNQYEETS 3600 IYITEENKPHVKAKKAHTASLVVSPGDTAEFDVVFHSQKVGRMRGIIHLSVINNQYEETS Sbjct: 3541 IYITEENKPHVKAKKAHTASLVVSPGDTAEFDVVFHSQKVGRMRGIIHLSVINNQYEETS 3600 Query: 3601 IHMVGEGYEDDITLDNIHGLVAPTSQEDISISEFTEIIEDNDMEDLVAAALVDHIQFGDC 3660 IHMVGEGYEDDITLDNIHGLVAPTSQEDISISEFTEIIEDNDMEDLVAAALVDHIQFGDC Sbjct: 3601 IHMVGEGYEDDITLDNIHGLVAPTSQEDISISEFTEIIEDNDMEDLVAAALVDHIQFGDC 3660 Query: 3661 HIGHSYNASFTVTNHSQVNLIRFEWPVSATIAFSPQMGHLHPGCAKDIVVTMKSDVPINL 3720 HIGHSYNASFTVTNHSQVNLIRFEWPVSATIAFSPQMGHLHPGCAKDIVVTMKSDVPINL Sbjct: 3661 HIGHSYNASFTVTNHSQVNLIRFEWPVSATIAFSPQMGHLHPGCAKDIVVTMKSDVPINL 3720 Query: 3721 KNMRIRCKLSRIMFQLPADQVPDWDDRMHTVKWVDVPRNMPGTFTTKRKVIETDPEPAHS 3780 KNMRIRCKLSRIMFQLPADQVPDWDDRMHTVKWVDVPRNMPGTFTTKRKVIETDPEPAHS Sbjct: 3721 KNMRIRCKLSRIMFQLPADQVPDWDDRMHTVKWVDVPRNMPGTFTTKRKVIETDPEPAHS 3780 Query: 3781 VLEENYQELQLQISANVDFASYHCQARDVRFKETLVYQTRVFEFDVINSGRVQLEFSWVS 3840 VLEENYQELQLQISANVDFASYHCQARDVRFKETLVYQTRVFEFDVINSGRVQLEFSWVS Sbjct: 3781 VLEENYQELQLQISANVDFASYHCQARDVRFKETLVYQTRVFEFDVINSGRVQLEFSWVS 3840 Query: 3841 EDTSKAVSFAKPDHQGSAQKDQLSQGTMHTGSTLDSTMDHWAEGSPQPFSVEPSSGIVPV 3900 EDTSKAVSFAKPDHQGSAQKDQLSQGTMHTGSTLDSTMDHWAEGSPQPFSVEPSSGIVPV Sbjct: 3841 EDTSKAVSFAKPDHQGSAQKDQLSQGTMHTGSTLDSTMDHWAEGSPQPFSVEPSSGIVPV 3900 Query: 3901 GKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTLPICHFDLKDSDYIS 3960 GKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTLPICHFDLKDSDYIS Sbjct: 3901 GKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTLPICHFDLKDSDYIS 3960 Query: 3961 GHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNLRTFTILNPTNSTYSFCWISEEIESL 4020 GHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNLRTFTILNPTNSTYSFCWISEEIESL Sbjct: 3961 GHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNLRTFTILNPTNSTYSFCWISEEIESL 4020 Query: 4021 QNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHLGITESSWTFLIPEHNITVPFLLVGKTTE 4080 QNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHLGITESSWTFLIPEHNITVPFLLVGKTTE Sbjct: 4021 QNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHLGITESSWTFLIPEHNITVPFLLVGKTTE 4080 Query: 4081 PLISLNKSHLNFSSLLIGREARETVQIINKEEQGFDFSFQDNSRYSEGFSNSLLVCPMEG 4140 PLISLNKSHLNFSSLLIGREARETVQIINKEEQGFDFSFQDNSRYSEGFSNSLLVCPMEG Sbjct: 4081 PLISLNKSHLNFSSLLIGREARETVQIINKEEQGFDFSFQDNSRYSEGFSNSLLVCPMEG 4140 Query: 4141 WIPPLSRFPIDIFFTPKQEGDVNFNLICNVEKKVHPVTLNVKAEGYTMNVEIKCKDRTGS 4200 WIPPLSRFPIDIFFTPKQEGDVNFNLICNVEKKVHPVTLNVKAEGYTMNVEIKCKDRTGS Sbjct: 4141 WIPPLSRFPIDIFFTPKQEGDVNFNLICNVEKKVHPVTLNVKAEGYTMNVEIKCKDRTGS 4200 Query: 4201 ITLLTPNQTNIINFYEVELNECVQCEFNFINTGKFTFSFQAQLCGSKTLLQYLEFSPIDS 4260 ITLLTPNQTNIINFYEVELNECVQCEFNFINTGKFTFSFQAQLCGSKTLLQYLEFSPIDS Sbjct: 4201 ITLLTPNQTNIINFYEVELNECVQCEFNFINTGKFTFSFQAQLCGSKTLLQYLEFSPIDS 4260 Query: 4261 TVDVGQSVHATLSFQPLKKCVLTDLELIIKISHGPTFMCNISGCAVSPAIHFSFTSYNFG 4320 TVDVGQSVHATLSFQPLKKCVLTDLELIIKISHGPTFMCNISGCAVSPAIHFSFTSYNFG Sbjct: 4261 TVDVGQSVHATLSFQPLKKCVLTDLELIIKISHGPTFMCNISGCAVSPAIHFSFTSYNFG 4320 Query: 4321 TCFIYQAGMPPYKQTLVITNKEETPMSIDCLYTNTTHLEVNSRVDVVKPGNTLEIPITFY 4380 TCFIYQAGMPPYKQTLVITNKEETPMSIDCLYTNTTHLEVNSRVDVVKPGNTLEIPITFY Sbjct: 4321 TCFIYQAGMPPYKQTLVITNKEETPMSIDCLYTNTTHLEVNSRVDVVKPGNTLEIPITFY 4380 Query: 4381 PRESINYQELIPFEINGLSQQTVEIKGKGTKMKILVLDPANRIVKLGAVLPGQVVKRTVS 4440 PRESINYQELIPFEINGLSQQTVEIKGKGTKMKILVLDPANRIVKLGAVLPGQVVKRTVS Sbjct: 4381 PRESINYQELIPFEINGLSQQTVEIKGKGTKMKILVLDPANRIVKLGAVLPGQVVKRTVS 4440 Query: 4441 IMNNSLAQLTFNQSILFTIPELQEPKVLTLAPFHNITLKPKEVCKLEVIFAPKKRVPPFS 4500 IMNNSLAQLTFNQSILFTIPELQEPKVLTLAPFHNITLKPKEVCKLEVIFAPKKRVPPFS Sbjct: 4441 IMNNSLAQLTFNQSILFTIPELQEPKVLTLAPFHNITLKPKEVCKLEVIFAPKKRVPPFS 4500 Query: 4501 EEVFMECMGLLRPLFLLSGCCQALEISLDQEHIPFGPVVYQTQATRRILMMNTGDVGARF 4560 EEVFMECMGLLRPLFLLSGCCQALEISLDQEHIPFGPVVYQTQATRRILMMNTGDVGARF Sbjct: 4501 EEVFMECMGLLRPLFLLSGCCQALEISLDQEHIPFGPVVYQTQATRRILMMNTGDVGARF 4560 Query: 4561 KWDIKKFEPHFSISPEEGYITSGMEVSFEVTYHPTEVGKESLCKNILCYIQGGSPLSLTL 4620 KWDIKKFEPHFSISPEEGYITSGMEVSFEVTYHPTEVGKESLCKNILCYIQGGSPLSLTL Sbjct: 4561 KWDIKKFEPHFSISPEEGYITSGMEVSFEVTYHPTEVGKESLCKNILCYIQGGSPLSLTL 4620 Query: 4621 SGVCVGPPAVKEVVNFTCQVRSKHTQTILLSNRTNQTWNLHPIFEGEHWEGPEFITLEAH 4680 SGVCVGPPAVKEVVNFTCQVRSKHTQTILLSNRTNQTWNLHPIFEGEHWEGPEFITLEAH Sbjct: 4621 SGVCVGPPAVKEVVNFTCQVRSKHTQTILLSNRTNQTWNLHPIFEGEHWEGPEFITLEAH 4680 Query: 4681 QQNKPYEITYRPRTMNLENRKHQGTLFFPLPDGTGWLYALHGTSELPKAVANIYREVPCK 4740 QQNKPYEITYRPRTMNLENRKHQGTLFFPLPDGTGWLYALHGTSELPKAVANIYREVPCK Sbjct: 4681 QQNKPYEITYRPRTMNLENRKHQGTLFFPLPDGTGWLYALHGTSELPKAVANIYREVPCK 4740 Query: 4741 TPYTELLPITNWLNKPQRFRVIVEILKPEKPDLSITMKGLDYIDVLSGSKKDYKLNFFSH 4800 TPYTELLPITNWLNKPQRFRVIVEILKPEKPDLSITMKGLDYIDVLSGSKKDYKLNFFSH Sbjct: 4741 TPYTELLPITNWLNKPQRFRVIVEILKPEKPDLSITMKGLDYIDVLSGSKKDYKLNFFSH 4800 Query: 4801 KEGTYAAKVIFRNEVTNEFLYYNVSFRVIPSGIIKTIEMVTPVRQVASASIKLENPLPYS 4860 KEGTYAAKVIFRNEVTNEFLYYNVSFRVIPSGIIKTIEMVTPVRQVASASIKLENPLPYS Sbjct: 4801 KEGTYAAKVIFRNEVTNEFLYYNVSFRVIPSGIIKTIEMVTPVRQVASASIKLENPLPYS 4860 Query: 4861 VTFSTECRMPDIALPSQFVVPANSEGTFSFEFQPLKAGETFGRLTLHNTDLGYYQYELYL 4920 VTFSTECRMPDIALPSQFVVPANSEGTFSFEFQPLKAGETFGRLTLHNTDLGYYQYELYL Sbjct: 4861 VTFSTECRMPDIALPSQFVVPANSEGTFSFEFQPLKAGETFGRLTLHNTDLGYYQYELYL 4920 Query: 4921 KATPALPEKPVHFQTVLGSSQIILVKFINYTRQRTEYYCRTDCTDFHAEKLINAAPGGQG 4980 KATPALPEKPVHFQTVLGSSQIILVKFINYTRQRTEYYCRTDCTDFHAEKLINAAPGGQG Sbjct: 4921 KATPALPEKPVHFQTVLGSSQIILVKFINYTRQRTEYYCRTDCTDFHAEKLINAAPGGQG 4980 Query: 4981 GTEASVEVLFEPSHLGETKGILILSSLAGGEYIIPLFGMALPPKPQGPFSIRAGYSIIIP 5040 GTEASVEVLFEPSHLGETKGILILSSLAGGEYIIPLFGMALPPKPQGPFSIRAGYSIIIP Sbjct: 4981 GTEASVEVLFEPSHLGETKGILILSSLAGGEYIIPLFGMALPPKPQGPFSIRAGYSIIIP 5040 Query: 5041 FKNVFYHMVTFSIIVDNPAFTIRAGESVRPKKINNITVSFEGNPSGSKTPITTKLTVSCP 5100 FKNVFYHMVTFSIIVDNPAFTIRAGESVRPKKINNITVSFEGNPSGSKTPITTKLTVSCP Sbjct: 5041 FKNVFYHMVTFSIIVDNPAFTIRAGESVRPKKINNITVSFEGNPSGSKTPITTKLTVSCP 5100 Query: 5101 PGEGSETGVKWVYYLKGITL 5120 PGEGSETGVKWVYYLKGITL Sbjct: 5101 PGEGSETGVKWVYYLKGITL 5120 >gi|46361983 hydrocephalus inducing isoform b [Homo sapiens] Length = 1017 Score = 2055 bits (5324), Expect = 0.0 Identities = 1014/1015 (99%), Positives = 1015/1015 (100%) Query: 1 MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE 60 MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE Sbjct: 1 MTSRRLEESMGAVQMGLVNMFKGFQSKVLPPLSPKVVTEEEVNRMLTPSEFLKEMSLTTE 60 Query: 61 QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL 120 QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL Sbjct: 61 QRLAKTRLMCRPQIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEVPL 120 Query: 121 ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC 180 ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC Sbjct: 121 ILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC 180 Query: 181 VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP 240 VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP Sbjct: 181 VTEREKFIVPIKARGARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTCRP 240 Query: 241 FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD 300 FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD Sbjct: 241 FSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLD 300 Query: 301 KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE 360 KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE Sbjct: 301 KNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDE 360 Query: 361 TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE 420 TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE Sbjct: 361 TDEFFEECITDPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAE 420 Query: 421 ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC 480 ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC Sbjct: 421 ITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHC 480 Query: 481 YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE 540 YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE Sbjct: 481 YEAILYNKGSIDALFNMTPPTSALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEE 540 Query: 541 FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK 600 FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK Sbjct: 541 FLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYK 600 Query: 601 LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT 660 LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT Sbjct: 601 LRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVT 660 Query: 661 LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL 720 LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL Sbjct: 661 LCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTL 720 Query: 721 QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV 780 QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV Sbjct: 721 QLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTV 780 Query: 781 YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ 840 YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ Sbjct: 781 YISIFGSQDPPLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ 840 Query: 841 AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS 900 AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS Sbjct: 841 AHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTFKDCVILDIENSSTYRIPVQAS 900 Query: 901 GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG 960 GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG Sbjct: 901 GTGSTIVSDKPFAPELNLGAHFSLDTHYYHFKLINKGRRIQQLFWMNDSFRPQAKLSKKG 960 Query: 961 RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPRI 1015 RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPR+ Sbjct: 961 RVKKGHAHVQPQPSGSQEPRDPQSPVFHLHPASMELYPGQAIDVILEGYSATPRV 1015 Score = 50.4 bits (119), Expect = 4e-05 Identities = 22/69 (31%), Positives = 39/69 (56%) Query: 1765 IFEIQPISGVLDPGEKSNVQVKFMPKEEKFYSQTLVFQIAQSAQKLTLLARGQGLEPRLE 1824 +F ++P+ G + P + + V F P E K Y QT+ I +L L +G+G+ P++ Sbjct: 403 VFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGEGMGPKIH 462 Query: 1825 FSPSVLDLG 1833 F+ +LD+G Sbjct: 463 FNFELLDIG 471 Score = 50.1 bits (118), Expect = 6e-05 Identities = 88/425 (20%), Positives = 161/425 (37%), Gaps = 71/425 (16%) Query: 3889 FSVEPSSGIVPVGKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPV-LVAKGRSTLP 3947 F P GI+ +Q ++ FS +G+FE + P PV L +G P Sbjct: 508 FVFSPKEGIIEPSGVQAIQISFSSTILGNFEEEFLVNVNGSPE----PVKLTIRGCVIGP 563 Query: 3948 ICHFDLK-----DSDYISGHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNLRTFTILN 4002 HF++ D + H L +S L P T + G+G K++ Sbjct: 564 TFHFNVPALHFGDVSFGFPHTLICSLNNTS---LIPMTYKLRIPGDGLGHKSI------- 613 Query: 4003 PTNSTYSFC----------WISEEIESLQNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHL 4052 S+C W EEI S++ P FT + G I P+ A I + T Sbjct: 614 ------SYCEQHVDYKRPSWTKEEISSMK-PKEFTISPDCGTIRPQGFAAI--RVTLCSN 664 Query: 4053 GITESSWTFLIPEHNI---TVPFLLVGKTTEPLISLNKSHLNFSSLLIGREARETVQIIN 4109 + + ++ I + L+ + P + L + ++F + +T+Q+ N Sbjct: 665 TVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGHCFLKYPYEKTLQLAN 724 Query: 4110 KEE-QGFDFSFQDNSRYSEGFSNSLLVCPM-EGWIPPLSRFPIDIFFTPKQEGDVNFNLI 4167 +++ GF ++ + E L P G I P S I + + G+ + Sbjct: 725 QDDLPGF---YEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTVY 781 Query: 4168 CNV-EKKVHPVTLNVKAEGYTMNVEIKCKDRTGSITLLTPNQTNIINFYEVELNECVQCE 4226 ++ + P+ ++K+ G G + + PNQ + N Y ++ + + Sbjct: 782 ISIFGSQDPPLVCHLKSAG------------EGPVIYVHPNQVDFGNIYVLKDSSRI--- 826 Query: 4227 FNFINTGKFTFSFQAQLCGSKTLL-----QYLEFSPIDSTVDVGQSVHATLSFQPLKKCV 4281 N N FQA + K+L + + D + + +++ TL+F K CV Sbjct: 827 LNLCNQSFIPAFFQAHMAHKKSLWTIEPNEGMVPPETDVQLALTANLNDTLTF---KDCV 883 Query: 4282 LTDLE 4286 + D+E Sbjct: 884 ILDIE 888 Score = 47.0 bits (110), Expect = 5e-04 Identities = 129/739 (17%), Positives = 250/739 (33%), Gaps = 141/739 (19%) Query: 3887 QPFSVEPSSGIVPVGKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTL 3946 +PFS+EP+ G + VG+ + +V+F P +GD L Sbjct: 239 RPFSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLI----------------------- 275 Query: 3947 PICHFDLKDSDYIS--GHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNLRTFTILNPT 4004 +C +D + ++S G + +R LD N+ IE T + + N RT TI N + Sbjct: 276 -VC-YDTGEKVFVSLYGAAIDMNIR------LDKNSLTIEKTYISLA--NQRTITIHNRS 325 Query: 4005 NSTYSFCWISEEIESLQNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHLGITESSWTFLIP 4064 N F W + ++ + + + E+K E F Sbjct: 326 NIIAHFLWKVFATQQEEDREKYRACDD---LIKEEKDETDEFF----------------- 365 Query: 4065 EHNITVPFLLVGKTTEPLISLNKSHLNFSSLLIGREARETVQIINKEEQGFDFSFQDNSR 4124 E IT P L + HL+ S + R ++ + + F Sbjct: 366 EECITDPLL-------------REHLSVLSRTFANQRR----LVQGDSKLF--------- 399 Query: 4125 YSEGFSNSLLVCPMEGWIPPLSRFPIDIFFTPKQEGDVNFNLICNVEKKVHPVTLNVKAE 4184 F+N V P+EG + P S I ++F P + + C++ + + L +K E Sbjct: 400 ----FNNVFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQQTIYCDILGREIRLPLRIKGE 455 Query: 4185 GYTMNVEIKCKDRTGSITLLTPNQTNIINFYEVELNECVQCEFNFINTGKFTFSFQAQLC 4244 G + + +++ +V E N G F Sbjct: 456 GMGPKIHFNFE---------------LLDIGKVFTGSAHCYEAILYNKGSIDALFN-MTP 499 Query: 4245 GSKTLLQYLEFSPIDSTVDVGQSVHATLSFQPLKKCVLTDL--ELIIKISHGP-TFMCNI 4301 + L FSP + ++ +SF +L + E ++ ++ P I Sbjct: 500 PTSALGACFVFSPKEGIIEPSGVQAIQISF---SSTILGNFEEEFLVNVNGSPEPVKLTI 556 Query: 4302 SGCAVSPAIHFSFTSYNFG----------TCFIYQAGMPPYKQTLVITNK-------EET 4344 GC + P HF+ + +FG C + + P L I Sbjct: 557 RGCVIGPTFHFNVPALHFGDVSFGFPHTLICSLNNTSLIPMTYKLRIPGDGLGHKSISYC 616 Query: 4345 PMSIDCLYTNTTHLEVNSR----------VDVVKPGNTLEIPITFYPRESINYQELIPFE 4394 +D + T E++S ++P I +T Y+ + + Sbjct: 617 EQHVDYKRPSWTKEEISSMKPKEFTISPDCGTIRPQGFAAIRVTLCSNTVQKYELALVVD 676 Query: 4395 INGLSQQTVEIKGKGTKMKILVLDPANRIVKLGAVLPGQVVKRTVSIMNNSLAQLTFNQS 4454 + G+ ++ + + + + L N V G ++T+ + N L Sbjct: 677 VEGIGEEVLALL-ITARCVVPALHLVNTEVDFGHCFLKYPYEKTLQLANQD--DLPGFYE 733 Query: 4455 ILFTIPELQEPKVLTLAPFHNITLKPKEVCKLEVIFAPKKRVPPFSEEVFMECMGLLRPL 4514 + + E + P VL +P + + P + ++ + V++ G P Sbjct: 734 VQPQVCE-EVPTVLFSSPTPSGVISPSSTIHIPLVLETQV-TGEHRSTVYISIFGSQDPP 791 Query: 4515 FL--LSGCCQALEISLDQEHIPFGPVVYQTQATRRILMMNTGDVGARFKWDIKKFEPHFS 4572 + L + I + + FG + ++R + + N + A F+ + + ++ Sbjct: 792 LVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQAHMAHKKSLWT 851 Query: 4573 ISPEEGYITSGMEVSFEVT 4591 I P EG + +V +T Sbjct: 852 IEPNEGMVPPETDVQLALT 870 Score = 40.4 bits (93), Expect = 0.046 Identities = 25/103 (24%), Positives = 47/103 (45%), Gaps = 4/103 (3%) Query: 2919 PAIFQLSCQGIRPELELEPRQLHFDRLLLHRQESRVVLLRNVTLLPVAWRITSLEHLGDD 2978 P + L G P + + P Q+ F + + + SR++ L N + +P ++ + H Sbjct: 791 PLVCHLKSAGEGPVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQ-AHMAHKKSL 849 Query: 2979 FTVSLMQGTIPPEAEYGLHLYFQPTKPVNIKKAIRLEVLDAEN 3021 +T+ +G +PPE + L L + K + +LD EN Sbjct: 850 WTIEPNEGMVPPETDVQLALTANLNDTLTFKDCV---ILDIEN 889 Score = 39.3 bits (90), Expect = 0.10 Identities = 20/94 (21%), Positives = 42/94 (44%) Query: 2876 YFLEPNTMVLKPNEKQILNVWAYPTSVGVFEDSIVCCINDNPEPAIFQLSCQGIRPELEL 2935 + P +++P+ Q + + T +G FE+ + +N +PEP + I P Sbjct: 508 FVFSPKEGIIEPSGVQAIQISFSSTILGNFEEEFLVNVNGSPEPVKLTIRGCVIGPTFHF 567 Query: 2936 EPRQLHFDRLLLHRQESRVVLLRNVTLLPVAWRI 2969 LHF + + + L N +L+P+ +++ Sbjct: 568 NVPALHFGDVSFGFPHTLICSLNNTSLIPMTYKL 601 Score = 33.9 bits (76), Expect = 4.3 Identities = 60/287 (20%), Positives = 112/287 (39%), Gaps = 32/287 (11%) Query: 4286 ELIIKISHGPTFMCNISGCAVSPAIHFSFTS----YNFGTCFIYQAGMPPYKQTLVITNK 4341 ++I + G T SG + A+ F S N+ C +Y+ L++ N Sbjct: 73 QIIELLDMGETTHQKFSGIDLDQALFQPFPSEIIFQNYTPCEVYEV-------PLILRNN 125 Query: 4342 EETPMSIDCLYTNTTHLEVNSRVDV---VKPGNTLEIPITFYPRESINYQELIPFEINGL 4398 ++ P + + ++ + +V S D+ V PG I F P E+ +Y + + Sbjct: 126 DKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLTC-VTER 184 Query: 4399 SQQTVEIKGKGTKMKILVLDPANRIVKLGAVLPGQVVKRTVSIMNNSLAQLTFNQSILFT 4458 + V IK +G + + D N + P + + + ++ N N++ +F Sbjct: 185 EKFIVPIKARGARAILDFPDKLNF-----STCPVKYSTQKILLVRN-----IGNKNAVFH 234 Query: 4459 IPELQEPKVLTLAPFHNITLKPKEVCKLEVIFAPKKRVPPFSEEVFMECMGLLRPLFL-L 4517 I + ++ P TL E +LEV F P+ V S + + C +F+ L Sbjct: 235 IKTCRP---FSIEPAIG-TLNVGESMQLEVEFEPQS-VGDHSGRLIV-CYDTGEKVFVSL 288 Query: 4518 SGCCQALEISLDQEHIPFGPVVYQTQATRRILMMNTGDVGARFKWDI 4564 G + I LD+ + R I + N ++ A F W + Sbjct: 289 YGAAIDMNIRLDKNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKV 335 Score = 32.7 bits (73), Expect = 9.5 Identities = 26/92 (28%), Positives = 43/92 (46%), Gaps = 10/92 (10%) Query: 4930 PVHFQTVLGSSQIILVKFINYTRQRTEYYCRTDCTDFHAEKLINAAPGGQGGTEASVEVL 4989 PV + T +I+LV+ N + ++ +T C F E I G+ +EV Sbjct: 212 PVKYST----QKILLVR--NIGNKNAVFHIKT-CRPFSIEPAIGTLNVGES---MQLEVE 261 Query: 4990 FEPSHLGETKGILILSSLAGGEYIIPLFGMAL 5021 FEP +G+ G LI+ G + + L+G A+ Sbjct: 262 FEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAI 293 >gi|90669228 deleted in lung and esophageal cancer 1 isoform DLEC1-S3 [Homo sapiens] Length = 1778 Score = 118 bits (296), Expect = 1e-25 Identities = 172/809 (21%), Positives = 307/809 (37%), Gaps = 111/809 (13%) Query: 94 DQALFQPFPSEIIFQNYTPCEVYEVPLILRNNDKIPRLVKVVEESSPYFKV---ISPKDI 150 D +F P F +Y VYE+ + L+N R ++V+ S+PYF + + P Sbjct: 368 DTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGLGMFPGK- 426 Query: 151 GHKVAPGVPSIFRILFTPEENKDYAHTLTCVTE-REKFIVPIKARGARAILDFPDKLNFS 209 G VAPG+ + + F P+ D+ + T+ ++P++AR +L L+ Sbjct: 427 GGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCG 486 Query: 210 TCPVKYSTQKILLVRNIGNKNAVFHI--KTC-----------------RPFSIEPAIGTL 250 C + + +N+G F I KT PF I P++ L Sbjct: 487 YCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGILPSVFEL 546 Query: 251 NVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLDKNSLTIEKTY 310 G ++ +EV F P+S+G I+ D + L I I LD ++ EK+ Sbjct: 547 APGHAILVEVLFSPKSLGKAEQTFIIMCDNCQ--IKELVTIGIGQLIALDLIYISGEKSQ 604 Query: 311 ISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDETDEFFEECIT 370 +T HF+ + E + + A LI + F I Sbjct: 605 PDPGELTDLTAQ-------HFI------RFEPENLRSTARKQLIIRNATHVELAFYWQIM 651 Query: 371 DPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAEITVYFNPLEA 430 P L+ + TF+ D + F++ P +G + P++ E + F+P E Sbjct: 652 KPNLQPLMP--GETFSMDSIKCYPDKE----TAFSIMPRKGVLSPHTDHEFILSFSPHEL 705 Query: 431 KLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHCYEAIL----- 485 + + + ++ E+ P+ + E +G + +++ + GS ++ +L Sbjct: 706 RDFHSVL--QMVLEEVPEPVSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYAL 763 Query: 486 ------YNKGSIDALFNMTPPTSA--------LGACFVF--SPKEGIIEPSGVQAIQISF 529 Y ++ F M + + + C + P G+IEPS V +++F Sbjct: 764 IIPGENYIGINVKKAFKMWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNF 823 Query: 530 SSTILGNFEEEFLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSL 589 + + G ++ L + SP PV L I GP NV AL FG + G T + Sbjct: 824 TGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQI 883 Query: 590 NNTSLIPMTYKLRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTI 649 N S +P T++++ + P +E + P F I P G + Sbjct: 884 RNVSQLPATWRMK--------------------ESPVSLQERPEDVSP--FDIEPSSGQL 921 Query: 650 RPQGFAAIRVTLCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGH 709 G + +TL + Q E L ++VE L + A P ++L +++V+ + Sbjct: 922 HSLGECRVDITLEALHCQHLETVLELEVENGAWSYLP--VYAEVQKPHVYLQSSQVEVRN 979 Query: 710 CFLKYPYEKTLQLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLE 769 +L P + T+ L N LP + + + + + G++ PS + L L Sbjct: 980 LYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVSPKHGLLGPSEECQLKLELT 1039 Query: 770 TQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYV----------------HPNQ-- 811 E PLV + +G + + HP + Sbjct: 1040 AHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKESSDCSTEQWPGHPKELR 1099 Query: 812 VDFGNIYVLKDS-SRILNLCNQSFIPAFF 839 +DFG+ L+ +R L L N+S I F Sbjct: 1100 LDFGSAVPLRTRVTRQLILTNRSPIRTRF 1128 Score = 45.8 bits (107), Expect = 0.001 Identities = 34/146 (23%), Positives = 63/146 (43%), Gaps = 7/146 (4%) Query: 2878 LEPNTMVLKPNEKQILNVWAYPTSVGVFEDSIVCCINDNPEPAIFQLSCQGIRPELELEP 2937 +EP T V++P+E + G ++C I D+P P + + P L + Sbjct: 804 VEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINV 863 Query: 2938 RQLHFDRLLLHRQESRVVLLRNVTLLPVAWRI----TSLEHLGDD---FTVSLMQGTIPP 2990 L F L L ++ + + +RNV+ LP WR+ SL+ +D F + G + Sbjct: 864 SALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDIEPSSGQLHS 923 Query: 2991 EAEYGLHLYFQPTKPVNIKKAIRLEV 3016 E + + + +++ + LEV Sbjct: 924 LGECRVDITLEALHCQHLETVLELEV 949 Score = 39.3 bits (90), Expect = 0.10 Identities = 33/155 (21%), Positives = 69/155 (44%), Gaps = 9/155 (5%) Query: 753 SGVISPSSTIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYVHPNQV 812 +GVI PS L V G + I S P +V H+++ +GP + ++ + + Sbjct: 808 TGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSP-VVLHIEAVFKGPALIINVSAL 866 Query: 813 DFGNIYVLKDSSRILNLCNQSFIPAFFQAHMA--------HKKSLWTIEPNEGMVPPETD 864 FG + + + ++ + + N S +PA ++ + S + IEP+ G + + Sbjct: 867 QFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDIEPSSGQLHSLGE 926 Query: 865 VQLALTANLNDTLTFKDCVILDIENSSTYRIPVQA 899 ++ +T + + L++EN + +PV A Sbjct: 927 CRVDITLEALHCQHLETVLELEVENGAWSYLPVYA 961 Score = 38.5 bits (88), Expect = 0.17 Identities = 91/407 (22%), Positives = 157/407 (38%), Gaps = 52/407 (12%) Query: 1271 RPEEKELRKTKASSVISDVRCPFHGEERIYSSQSQVEDQESLQTCEQNEMLSIGI----E 1326 R E + LR T +I +R H E Y Q + + L E M SI E Sbjct: 620 RFEPENLRSTARKQLI--IRNATHVELAFYW-QIMKPNLQPLMPGETFSMDSIKCYPDKE 676 Query: 1327 EVFDILPLFGVLQPHSSHQISFTFYGHA----NIIAQAKALCEVEEGPTYEITLKGEASL 1382 F I+P GVL PH+ H+ +F H + + Q L EV E + E G +S Sbjct: 677 TAFSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQ-MVLEEVPEPVSSEAESLGHSS- 734 Query: 1383 VNYSFDTK-----DIHYGLQLFDHVTE-REITLTNMGKVGFEFK---VLTDHQSSPDNLL 1433 YS D ++ ++ F + E + + +G K + ++ SP L Sbjct: 735 --YSVDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFKMWNNSKSPIRYL 792 Query: 1434 PG------VPLILPVSGFISSHQEQVLKVYYLPGVPEVFKRSFQIQIAHLDPENITLSGE 1487 G + + P +G I + ++ + GVP + +I P + L E Sbjct: 793 WGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIED-SPSPVVLHIE 851 Query: 1488 GIFPQICLDLPRNLTANEKYEMFLNQARKNTDKEYNKCEM-----LDHFDIITEEVPED- 1541 +F L + N++A + + L Q N+ + N ++ + + +E PED Sbjct: 852 AVFKGPALII--NVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDV 909 Query: 1542 -----EPAEVSAHLQMEVE-RLIVQSYVLEHQKTTTPDPMDDPCFSHRSRRKLAKIQLPE 1595 EP+ H E + +++ +H +T +++ +S+ A++Q P Sbjct: 910 SPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLP--VYAEVQKPH 967 Query: 1596 YILDFGYI-----ILGEVRTHIIKIINTSHFPVSFHADKRVLHETGF 1637 L + LG I +IN + P FH K + H+ F Sbjct: 968 VYLQSSQVEVRNLYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEF 1014 Score = 36.6 bits (83), Expect = 0.66 Identities = 49/227 (21%), Positives = 88/227 (38%), Gaps = 26/227 (11%) Query: 3889 FSVEPSSGIVPVGKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTLPI 3948 FS+ P G++ +F + FSP ++ DF S L + E+ P V+ +L Sbjct: 679 FSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVL------EEVPEPVSSEAESLGH 732 Query: 3949 CHFDLKDSDYISGHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNL------RTFTILN 4002 + + D + E++GS ++P ++E + I G+N + F + N Sbjct: 733 SSYSVDDVIVL-----EIEVKGS----VEPFQVLLEPYALIIPGENYIGINVKKAFKMWN 783 Query: 4003 PTNSTYSFCWISEEIESLQNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHLGITESSWTFL 4062 + S + W + + G I P + + FT G T Sbjct: 784 NSKSPIRYLW-----GKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCE 838 Query: 4063 IPEHNITVPFLLVGKTTEPLISLNKSHLNFSSLLIGREARETVQIIN 4109 I + V + P + +N S L F L +G++A ++QI N Sbjct: 839 IEDSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRN 885 Score = 35.8 bits (81), Expect = 1.1 Identities = 86/480 (17%), Positives = 185/480 (38%), Gaps = 57/480 (11%) Query: 4135 VCPMEGWIPPLSRFPIDIFFTPKQEGDVNFNLICNVEKKVHPVTLNVKAEGYT------- 4187 + P +G + P + + F+P + D + L +E+ PV+ ++ G++ Sbjct: 681 IMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVPEPVSSEAESLGHSSYSVDDV 740 Query: 4188 --MNVEIKCKDRTGSI----TLLTPNQTNIINFYEVELNECVQCEFNFINTGKFTFSFQA 4241 + +E+K GS+ LL P I + +N V+ F N K + Sbjct: 741 IVLEIEVK-----GSVEPFQVLLEPYALIIPGENYIGIN--VKKAFKMWNNSKSPIRY-- 791 Query: 4242 QLCGSKTLLQYLEFSPIDSTVDVGQSVHATLSFQPLKKCVLTDLELIIKISHGPT-FMCN 4300 L G + +E P ++ + L+F T +L+ +I P+ + + Sbjct: 792 -LWGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGP-TSQDLLCEIEDSPSPVVLH 849 Query: 4301 ISGCAVSPAIHFSFTSYNFGTCFIYQAGMPPYK-----QTLVITNKEETPMSIDCLYTNT 4355 I PA+ + ++ FG + Q + Q +E+P+S+ + Sbjct: 850 IEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDV 909 Query: 4356 THLEVNSRVDVVKPGNTLEIPITFYPRESINYQELIPFEINGLSQQTVEIKGKGTKMKIL 4415 + ++ + + IT + + ++ E+ + + + + K + Sbjct: 910 SPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVYAEVQKPHVY 969 Query: 4416 VLDPANRIVKLGAVLPGQVVKRTVSIMNNSLAQLTFNQSILFTIPELQEPKVLTLAPFHN 4475 + + L +P K T++++N +L F+ L + E ++T++P H Sbjct: 970 LQSSQVEVRNLYLGVP---TKTTITLINGTLLPTQFHWGKL--LGHQAEFCMVTVSPKHG 1024 Query: 4476 ITLKPKEVCKLEVIFAPKKRVPPFSEEVFMECMGLLRPLFL-LSGCCQALEISLD----- 4529 + L P E C+L++ + + G+ +PL L +SG Q L++++ Sbjct: 1025 L-LGPSEECQLKLELTAHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKES 1083 Query: 4530 -------------QEHIPFGPVV-YQTQATRRILMMNTGDVGARFKWDIKKF-EPHFSIS 4574 + + FG V +T+ TR++++ N + RF + F P S+S Sbjct: 1084 SDCSTEQWPGHPKELRLDFGSAVPLRTRVTRQLILTNRSPIRTRFSLKFEYFGSPQNSLS 1143 >gi|90669194 deleted in lung and esophageal cancer 1 isoform DLEC1-N1 [Homo sapiens] Length = 1755 Score = 118 bits (296), Expect = 1e-25 Identities = 172/809 (21%), Positives = 307/809 (37%), Gaps = 111/809 (13%) Query: 94 DQALFQPFPSEIIFQNYTPCEVYEVPLILRNNDKIPRLVKVVEESSPYFKV---ISPKDI 150 D +F P F +Y VYE+ + L+N R ++V+ S+PYF + + P Sbjct: 368 DTPVFLAKPPIGFFTDYEIGPVYEMVIALQNTTTTSRYLRVLPPSTPYFALGLGMFPGK- 426 Query: 151 GHKVAPGVPSIFRILFTPEENKDYAHTLTCVTE-REKFIVPIKARGARAILDFPDKLNFS 209 G VAPG+ + + F P+ D+ + T+ ++P++AR +L L+ Sbjct: 427 GGMVAPGMTCQYIVQFFPDCLGDFDDFILVETQSAHTLLIPLQARRPPPVLTLSPVLDCG 486 Query: 210 TCPVKYSTQKILLVRNIGNKNAVFHI--KTC-----------------RPFSIEPAIGTL 250 C + + +N+G F I KT PF I P++ L Sbjct: 487 YCLIGGVKMTRFICKNVGFSVGRFCIMPKTSWPPLSFKAIATVGFVEQPPFGILPSVFEL 546 Query: 251 NVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAIDMNIRLDKNSLTIEKTY 310 G ++ +EV F P+S+G I+ D + L I I LD ++ EK+ Sbjct: 547 APGHAILVEVLFSPKSLGKAEQTFIIMCDNCQ--IKELVTIGIGQLIALDLIYISGEKSQ 604 Query: 311 ISLANQRTITIHNRSNIIAHFLWKVFATQQEEDREKYRACDDLIKEEKDETDEFFEECIT 370 +T HF+ + E + + A LI + F I Sbjct: 605 PDPGELTDLTAQ-------HFI------RFEPENLRSTARKQLIIRNATHVELAFYWQIM 651 Query: 371 DPLLREHLSVLSRTFANQRRLVQGDSKLFFNNVFTVEPLEGDVWPNSSAEITVYFNPLEA 430 P L+ + TF+ D + F++ P +G + P++ E + F+P E Sbjct: 652 KPNLQPLMP--GETFSMDSIKCYPDKE----TAFSIMPRKGVLSPHTDHEFILSFSPHEL 705 Query: 431 KLYQQTIYCDILGREIRLPLRIKGEGMGPKIHFNFELLDIGKVFTGSAHCYEAIL----- 485 + + + ++ E+ P+ + E +G + +++ + GS ++ +L Sbjct: 706 RDFHSVL--QMVLEEVPEPVSSEAESLGHSSYSVDDVIVLEIEVKGSVEPFQVLLEPYAL 763 Query: 486 ------YNKGSIDALFNMTPPTSA--------LGACFVF--SPKEGIIEPSGVQAIQISF 529 Y ++ F M + + + C + P G+IEPS V +++F Sbjct: 764 IIPGENYIGINVKKAFKMWNNSKSPIRYLWGKISDCHIIEVEPGTGVIEPSEVGDFELNF 823 Query: 530 SSTILGNFEEEFLVNVNGSPEPVKLTIRGCVIGPTFHFNVPALHFGDVSFGFPHTLICSL 589 + + G ++ L + SP PV L I GP NV AL FG + G T + Sbjct: 824 TGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQI 883 Query: 590 NNTSLIPMTYKLRIPGDGLGHKSISYCEQHVDYKRPSWTKEEISSMKPKEFTISPDCGTI 649 N S +P T++++ + P +E + P F I P G + Sbjct: 884 RNVSQLPATWRMK--------------------ESPVSLQERPEDVSP--FDIEPSSGQL 921 Query: 650 RPQGFAAIRVTLCSNTVQKYELALVVDVEGIGEEVLALLITARCVVPALHLVNTEVDFGH 709 G + +TL + Q E L ++VE L + A P ++L +++V+ + Sbjct: 922 HSLGECRVDITLEALHCQHLETVLELEVENGAWSYLP--VYAEVQKPHVYLQSSQVEVRN 979 Query: 710 CFLKYPYEKTLQLANQDDLPGFYEVQPQVCEEVPTVLFSSPTPSGVISPSSTIHIPLVLE 769 +L P + T+ L N LP + + + + + G++ PS + L L Sbjct: 980 LYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEFCMVTVSPKHGLLGPSEECQLKLELT 1039 Query: 770 TQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYV----------------HPNQ-- 811 E PLV + +G + + HP + Sbjct: 1040 AHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKESSDCSTEQWPGHPKELR 1099 Query: 812 VDFGNIYVLKDS-SRILNLCNQSFIPAFF 839 +DFG+ L+ +R L L N+S I F Sbjct: 1100 LDFGSAVPLRTRVTRQLILTNRSPIRTRF 1128 Score = 45.8 bits (107), Expect = 0.001 Identities = 34/146 (23%), Positives = 63/146 (43%), Gaps = 7/146 (4%) Query: 2878 LEPNTMVLKPNEKQILNVWAYPTSVGVFEDSIVCCINDNPEPAIFQLSCQGIRPELELEP 2937 +EP T V++P+E + G ++C I D+P P + + P L + Sbjct: 804 VEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSPVVLHIEAVFKGPALIINV 863 Query: 2938 RQLHFDRLLLHRQESRVVLLRNVTLLPVAWRI----TSLEHLGDD---FTVSLMQGTIPP 2990 L F L L ++ + + +RNV+ LP WR+ SL+ +D F + G + Sbjct: 864 SALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDIEPSSGQLHS 923 Query: 2991 EAEYGLHLYFQPTKPVNIKKAIRLEV 3016 E + + + +++ + LEV Sbjct: 924 LGECRVDITLEALHCQHLETVLELEV 949 Score = 39.3 bits (90), Expect = 0.10 Identities = 33/155 (21%), Positives = 69/155 (44%), Gaps = 9/155 (5%) Query: 753 SGVISPSSTIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAGEGPVIYVHPNQV 812 +GVI PS L V G + I S P +V H+++ +GP + ++ + + Sbjct: 808 TGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIEDSPSP-VVLHIEAVFKGPALIINVSAL 866 Query: 813 DFGNIYVLKDSSRILNLCNQSFIPAFFQAHMA--------HKKSLWTIEPNEGMVPPETD 864 FG + + + ++ + + N S +PA ++ + S + IEP+ G + + Sbjct: 867 QFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDVSPFDIEPSSGQLHSLGE 926 Query: 865 VQLALTANLNDTLTFKDCVILDIENSSTYRIPVQA 899 ++ +T + + L++EN + +PV A Sbjct: 927 CRVDITLEALHCQHLETVLELEVENGAWSYLPVYA 961 Score = 38.5 bits (88), Expect = 0.17 Identities = 91/407 (22%), Positives = 157/407 (38%), Gaps = 52/407 (12%) Query: 1271 RPEEKELRKTKASSVISDVRCPFHGEERIYSSQSQVEDQESLQTCEQNEMLSIGI----E 1326 R E + LR T +I +R H E Y Q + + L E M SI E Sbjct: 620 RFEPENLRSTARKQLI--IRNATHVELAFYW-QIMKPNLQPLMPGETFSMDSIKCYPDKE 676 Query: 1327 EVFDILPLFGVLQPHSSHQISFTFYGHA----NIIAQAKALCEVEEGPTYEITLKGEASL 1382 F I+P GVL PH+ H+ +F H + + Q L EV E + E G +S Sbjct: 677 TAFSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQ-MVLEEVPEPVSSEAESLGHSS- 734 Query: 1383 VNYSFDTK-----DIHYGLQLFDHVTE-REITLTNMGKVGFEFK---VLTDHQSSPDNLL 1433 YS D ++ ++ F + E + + +G K + ++ SP L Sbjct: 735 --YSVDDVIVLEIEVKGSVEPFQVLLEPYALIIPGENYIGINVKKAFKMWNNSKSPIRYL 792 Query: 1434 PG------VPLILPVSGFISSHQEQVLKVYYLPGVPEVFKRSFQIQIAHLDPENITLSGE 1487 G + + P +G I + ++ + GVP + +I P + L E Sbjct: 793 WGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCEIED-SPSPVVLHIE 851 Query: 1488 GIFPQICLDLPRNLTANEKYEMFLNQARKNTDKEYNKCEM-----LDHFDIITEEVPED- 1541 +F L + N++A + + L Q N+ + N ++ + + +E PED Sbjct: 852 AVFKGPALII--NVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDV 909 Query: 1542 -----EPAEVSAHLQMEVE-RLIVQSYVLEHQKTTTPDPMDDPCFSHRSRRKLAKIQLPE 1595 EP+ H E + +++ +H +T +++ +S+ A++Q P Sbjct: 910 SPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLP--VYAEVQKPH 967 Query: 1596 YILDFGYI-----ILGEVRTHIIKIINTSHFPVSFHADKRVLHETGF 1637 L + LG I +IN + P FH K + H+ F Sbjct: 968 VYLQSSQVEVRNLYLGVPTKTTITLINGTLLPTQFHWGKLLGHQAEF 1014 Score = 36.6 bits (83), Expect = 0.66 Identities = 49/227 (21%), Positives = 88/227 (38%), Gaps = 26/227 (11%) Query: 3889 FSVEPSSGIVPVGKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTLPI 3948 FS+ P G++ +F + FSP ++ DF S L + E+ P V+ +L Sbjct: 679 FSIMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVL------EEVPEPVSSEAESLGH 732 Query: 3949 CHFDLKDSDYISGHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNL------RTFTILN 4002 + + D + E++GS ++P ++E + I G+N + F + N Sbjct: 733 SSYSVDDVIVL-----EIEVKGS----VEPFQVLLEPYALIIPGENYIGINVKKAFKMWN 783 Query: 4003 PTNSTYSFCWISEEIESLQNPAAFTCLTEKGFIHPEKKAEIVFQFTPFHLGITESSWTFL 4062 + S + W + + G I P + + FT G T Sbjct: 784 NSKSPIRYLW-----GKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGPTSQDLLCE 838 Query: 4063 IPEHNITVPFLLVGKTTEPLISLNKSHLNFSSLLIGREARETVQIIN 4109 I + V + P + +N S L F L +G++A ++QI N Sbjct: 839 IEDSPSPVVLHIEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRN 885 Score = 35.8 bits (81), Expect = 1.1 Identities = 86/480 (17%), Positives = 185/480 (38%), Gaps = 57/480 (11%) Query: 4135 VCPMEGWIPPLSRFPIDIFFTPKQEGDVNFNLICNVEKKVHPVTLNVKAEGYT------- 4187 + P +G + P + + F+P + D + L +E+ PV+ ++ G++ Sbjct: 681 IMPRKGVLSPHTDHEFILSFSPHELRDFHSVLQMVLEEVPEPVSSEAESLGHSSYSVDDV 740 Query: 4188 --MNVEIKCKDRTGSI----TLLTPNQTNIINFYEVELNECVQCEFNFINTGKFTFSFQA 4241 + +E+K GS+ LL P I + +N V+ F N K + Sbjct: 741 IVLEIEVK-----GSVEPFQVLLEPYALIIPGENYIGIN--VKKAFKMWNNSKSPIRY-- 791 Query: 4242 QLCGSKTLLQYLEFSPIDSTVDVGQSVHATLSFQPLKKCVLTDLELIIKISHGPT-FMCN 4300 L G + +E P ++ + L+F T +L+ +I P+ + + Sbjct: 792 -LWGKISDCHIIEVEPGTGVIEPSEVGDFELNFTGGVPGP-TSQDLLCEIEDSPSPVVLH 849 Query: 4301 ISGCAVSPAIHFSFTSYNFGTCFIYQAGMPPYK-----QTLVITNKEETPMSIDCLYTNT 4355 I PA+ + ++ FG + Q + Q +E+P+S+ + Sbjct: 850 IEAVFKGPALIINVSALQFGLLRLGQKATNSIQIRNVSQLPATWRMKESPVSLQERPEDV 909 Query: 4356 THLEVNSRVDVVKPGNTLEIPITFYPRESINYQELIPFEINGLSQQTVEIKGKGTKMKIL 4415 + ++ + + IT + + ++ E+ + + + + K + Sbjct: 910 SPFDIEPSSGQLHSLGECRVDITLEALHCQHLETVLELEVENGAWSYLPVYAEVQKPHVY 969 Query: 4416 VLDPANRIVKLGAVLPGQVVKRTVSIMNNSLAQLTFNQSILFTIPELQEPKVLTLAPFHN 4475 + + L +P K T++++N +L F+ L + E ++T++P H Sbjct: 970 LQSSQVEVRNLYLGVP---TKTTITLINGTLLPTQFHWGKL--LGHQAEFCMVTVSPKHG 1024 Query: 4476 ITLKPKEVCKLEVIFAPKKRVPPFSEEVFMECMGLLRPLFL-LSGCCQALEISLD----- 4529 + L P E C+L++ + + G+ +PL L +SG Q L++++ Sbjct: 1025 L-LGPSEECQLKLELTAHTQEELTHLALPCHVSGMKKPLVLGISGKPQGLQVAITISKES 1083 Query: 4530 -------------QEHIPFGPVV-YQTQATRRILMMNTGDVGARFKWDIKKF-EPHFSIS 4574 + + FG V +T+ TR++++ N + RF + F P S+S Sbjct: 1084 SDCSTEQWPGHPKELRLDFGSAVPLRTRVTRQLILTNRSPIRTRFSLKFEYFGSPQNSLS 1143 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 80.1 bits (196), Expect = 5e-14 Identities = 74/327 (22%), Positives = 165/327 (50%), Gaps = 43/327 (13%) Query: 2272 MKAQEKAKKEQEE-RKHKGALEKEKERLQNMDE---EEYDALTEEEKLTFDRGIQQALRE 2327 ++ QEK +EQ+E R+ + +++++E++ +E E+ + + +E+ +++ Q +E Sbjct: 330 LREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQE 389 Query: 2328 RKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387 +K R+QE E Q+++L+++ ER +E++++ +V+K ++EE M++ + + Sbjct: 390 QKMRDQEERMWE-QDERLREKEERMREQEKMWEQVEK-----MREEKKMQEQEKKTRDQE 443 Query: 2388 PLTKVDVKMETIERKISVREQTMSEKEE-LNKKKRNMGDVSMHGLPLVQDQEDSEGDNSK 2446 + + ++ E+K+ E+TM E+EE + K++ NM + QE+ E + Sbjct: 444 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWE-----------QEEKEWQQQR 492 Query: 2447 DPDKQLAPKFKTYELTLKDVQNILMYWDRKQGV--------QLPPAGMEEAPHEPDDQRQ 2498 P++ K K +E Q + W++++ + Q +E E +DQ Sbjct: 493 LPEQ----KEKLWEQEKMQEQEEKI-WEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMW 547 Query: 2499 VPLGGRRGRKDRERERL---EKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDH 2555 + K R++E+ ++ER EK+ E+EK ++ EK+R E + E + E+ Sbjct: 548 -----EQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE 602 Query: 2556 EGKKEKDLGVPFLDIQTPDFEGLSWKQ 2582 E +E++ + + + + E W+Q Sbjct: 603 EMMREQEEKMQEQEEKMQEQEEKMWEQ 629 Score = 73.9 bits (180), Expect = 4e-12 Identities = 78/319 (24%), Positives = 142/319 (44%), Gaps = 27/319 (8%) Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324 M + M QEK +EQE+ + EKE + + E+E +EEK+ + Sbjct: 309 MREQEEKMWRQEKRLREQEKELREQ--EKELREQKELREQEEQMQEQEEKMWEQEEKMRE 366 Query: 2325 LRERKKREQERL---AKEM--QEKKLQQELERQKEEDE--------LKRRVKKGKQ-GPI 2370 E+ R++ERL K+M QE+K++ + ER E+DE ++ + K +Q + Sbjct: 367 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKM 426 Query: 2371 KEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEE-LNKKKRNMGDVSMH 2429 +EE M++ + + + + ++ E+K+ E+TM E+EE + K++ NM + Sbjct: 427 REEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEK 486 Query: 2430 GLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNI-----LMYWDRKQGVQLPPA 2484 + E E ++ ++ K E ++D + + M+ K Q Sbjct: 487 EWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQM 546 Query: 2485 GMEEAPHEPDDQRQVPLGGRRGRKDRERERL-----EKERTEKERLEREKAERERLEKLR 2539 +E +Q+ R +K +E+E+ EK R E+ EREK RE E +R Sbjct: 547 WEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMR 606 Query: 2540 ALEERSDWEGEGEEDHEGK 2558 EE+ + E ++ E K Sbjct: 607 EQEEKMQEQEEKMQEQEEK 625 Score = 73.2 bits (178), Expect = 6e-12 Identities = 72/307 (23%), Positives = 141/307 (45%), Gaps = 26/307 (8%) Query: 2265 MAQDYAAMKAQEKAKKEQEERK-HKGALEKEKERL---QNMDEEEYDALTEEEKLTFDRG 2320 M + M+ QE+ EQEE++ + L ++KE+L + M E+E +EEK+ Sbjct: 466 MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE 525 Query: 2321 I----QQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPM 2376 + ++ R+ K REQE E +EK QE + +E+ ++++ ++ ++ +E M Sbjct: 526 MWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKM 585 Query: 2377 KKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQD 2436 ++ + ++ + + + M E K+ +E+ M E+EE ++ +Q+ Sbjct: 586 REEERMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEK----------MQE 635 Query: 2437 QEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQ 2496 QE+ + +K + K +E Q ++ K Q EE E + Sbjct: 636 QEEKMWEQE---EKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKM 692 Query: 2497 RQVPLGGRRGRKDRERERLEKERTEKERLEREKAE--RERLEKLRALEERSDWEGEGEED 2554 + + D+E+ R E+ E+E+ RE+ E RE+ EK++ EE+ E EE+ Sbjct: 693 EKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQ---EQEEE 749 Query: 2555 HEGKKEK 2561 ++EK Sbjct: 750 MWEQEEK 756 Score = 71.6 bits (174), Expect = 2e-11 Identities = 65/297 (21%), Positives = 148/297 (49%), Gaps = 15/297 (5%) Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKR 2331 M+ QEK ++QEE+ + E+ +ER + M EEE +EEK+ +E K+ Sbjct: 432 MQEQEKKTRDQEEKMQEE--ERIREREKKMREEEETMREQEEKMQKQEENMWE-QEEKEW 488 Query: 2332 EQERLAKEMQEKKLQQELERQKE---EDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPP 2388 +Q+RL ++ ++ Q++++ Q+E E E K R ++ G +E M + + +Q Sbjct: 489 QQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWG---QEKKMWRQEKMREQEDQ 545 Query: 2389 LTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDP 2448 + + + KM E+K+ +E+ M +K + +KK + M ++++E + + Sbjct: 546 MWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 605 Query: 2449 DKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRK 2508 +Q K + E +++ + + W++++ +Q M E + +Q + +R + Sbjct: 606 REQ-EEKMQEQEEKMQEQEEKM--WEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPE 662 Query: 2509 DRERERLEKERTEKERLEREKA---ERERLEKLRALEERSDWEGEGEEDHEGKKEKD 2562 +E+ ++ E+E+++ ++ E+E++EK +E+ W+ E + E +E++ Sbjct: 663 QKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE 719 Score = 68.2 bits (165), Expect = 2e-10 Identities = 69/308 (22%), Positives = 149/308 (48%), Gaps = 43/308 (13%) Query: 2265 MAQDYAAMKAQEKAKKEQEER--KHKGALEKEKERLQNMDE------------------- 2303 M ++ M+ QE+ +EQEE+ + + + +++E++Q +E Sbjct: 598 MREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQ 657 Query: 2304 ----EEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQE-KKLQQELERQKEEDEL 2358 E+ + L E EK+ +Q+ +E K EQE++ K+ QE +K + E+ +EE+ + Sbjct: 658 QRLPEQKEKLWEHEKMQEQEKMQE--QEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESM 715 Query: 2359 KRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNK 2418 + R KK ++ +EE ++ + +Q + + + +M E K+ +E+ M E++ L + Sbjct: 716 REREKKMRE---EEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPE 772 Query: 2419 KKRNMGD-VSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQ 2477 +K + + M + +QE+ D + Q K + E ++ + + + K Sbjct: 773 QKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ-EEKMRGQEEKMRGQEEKMWGQEEKM 831 Query: 2478 -GVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLE 2536 G + G EE +++ + + +G++++ RE+ EK R ++E++ RE+ E Sbjct: 832 WGQEEKMWGQEEKMWGQEEKMEEKM---QGQEEKMREQEEKMRGQEEKM------REQEE 882 Query: 2537 KLRALEER 2544 K+R EE+ Sbjct: 883 KMRGQEEK 890 Score = 65.9 bits (159), Expect = 1e-09 Identities = 61/314 (19%), Positives = 149/314 (47%), Gaps = 31/314 (9%) Query: 2287 HKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQEKKLQ 2346 ++ + E+ + +N + +E L E EK +++ +RK + L ++Q LQ Sbjct: 214 YRNTITNEELKKKNAELQEKLPLAESEKSEIQLNVKEL--KRKLERAKFLLPQVQTNTLQ 271 Query: 2347 QELERQKEE-DELKRRVKKGKQGPIKEEPPMKKSQAA-NKQVPPLTKVDVKMETIERKIS 2404 +E+ RQ+EE E +++++K ++ ++E +++ + +Q + + + ++ E+++ Sbjct: 272 EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELR 331 Query: 2405 VREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLK 2464 +E+ + E++EL +++ M Q+QE+ + + +Q ++ E Sbjct: 332 EQEKELREQKELREQEEQM-----------QEQEEKMWEQEEKMREQEEKMWRQEE---- 376 Query: 2465 DVQNILMYWDRKQGVQLPPAGMEEAPHE--PDDQRQVPLGGRRGRKDRERERLEKERTEK 2522 W++++ ++ M + D+R R +++ E++EK R EK Sbjct: 377 ------RLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEK 430 Query: 2523 ERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQ 2582 + E+EK R++ EK++ E + E + E+ E +E++ + + + E W+Q Sbjct: 431 KMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 490 Query: 2583 ALESDKLPKGEQIL 2596 +LP+ ++ L Sbjct: 491 ----QRLPEQKEKL 500 Score = 65.5 bits (158), Expect = 1e-09 Identities = 63/313 (20%), Positives = 161/313 (51%), Gaps = 36/313 (11%) Query: 2273 KAQEKAKKEQEE----RKHKGALEKEKERLQNMDE---EEYDALTEEEKLTFDRGIQQAL 2325 + +E+ KK +EE R+ + +++++E++Q +E E+ + + E+E+ +++ + Sbjct: 590 RMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWE 649 Query: 2326 RERKKREQERLAKEMQE----KKLQQELERQKEEDELKRRVKKGKQGPIKE-----EPPM 2376 +E K EQ+RL ++ ++ +K+Q++ + Q++E+++ + K K+ +E + M Sbjct: 650 QEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKM 709 Query: 2377 KKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEE---LNKKKRNMGDVSMHGLPL 2433 ++ ++ ++ + + + M E K+ +E+ M E+EE ++K + M Sbjct: 710 REEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQR 769 Query: 2434 VQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEP 2493 + +Q++ ++ K +++ K E ++D + ++ +G + G EE Sbjct: 770 LPEQKEKLWEHEKMQEQE---KIWEQEEKMRDQE------EKMRGQEEKMRGQEEKMRGQ 820 Query: 2494 DDQ---RQVPLGGRRGRKDRERERL--EKERTEKERLEREKAERERLEKLRALEERSDWE 2548 +++ ++ + G+ + + E++ ++E+ E++ +E+ RE+ EK+R EE+ Sbjct: 821 EEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKM--- 877 Query: 2549 GEGEEDHEGKKEK 2561 E EE G++EK Sbjct: 878 REQEEKMRGQEEK 890 Score = 63.9 bits (154), Expect = 4e-09 Identities = 77/325 (23%), Positives = 166/325 (51%), Gaps = 31/325 (9%) Query: 2272 MKAQEKAKKEQEE--RKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERK 2329 M QE+ +EQE+ RK + + +++ERL+ E+E +EEK+ ++ LRE++ Sbjct: 274 MWRQEEELREQEKKIRKQEEKMWRQEERLR---EQEGKMREQEEKMWRQ---EKRLREQE 327 Query: 2330 K--REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387 K REQE+ +E +E + Q+E + Q++E+++ + +K ++ +EE ++ + +Q Sbjct: 328 KELREQEKELREQKELREQEE-QMQEQEEKMWEQEEKMRE---QEEKMWRQEERLWEQEK 383 Query: 2388 PLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGD--VSMHGLPLVQDQEDSEGDNS 2445 + + + KM E ++ +++ + EKEE +++ M + M +Q+QE D Sbjct: 384 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRD-- 441 Query: 2446 KDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVP----- 2500 ++ Q + + E +++ + + ++++ +Q M E + Q+++P Sbjct: 442 QEEKMQEEERIREREKKMREEEETMR--EQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 499 Query: 2501 LGGRRGRKDRER---ERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEG 2557 L + +++E E+ EK R ++E +EK + R EK+R E++ WE E + + Sbjct: 500 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEK-KMWRQEKMREQEDQM-WEQEEKMRDQE 557 Query: 2558 KKEKDLGVPFLDIQTPDFEGLSWKQ 2582 +K D ++ +T + E +W Q Sbjct: 558 QKMWD-QEERMEKKTQEQEKKTWDQ 581 Score = 58.2 bits (139), Expect = 2e-07 Identities = 62/272 (22%), Positives = 127/272 (46%), Gaps = 47/272 (17%) Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLT 2316 +E ++ Q+ M+ QE+ EQ EK +++ Q +++ +D +EK+ Sbjct: 664 KEKLWEHEKMQEQEKMQEQEEKIWEQ---------EKMEKKTQEQEKKTWD----QEKMR 710 Query: 2317 FDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPM 2376 + +++ RE+K RE+E + +E +EK +QE + Q++E+E+ + +K ++E M Sbjct: 711 EEESMRE--REKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEK----MWEQEEKM 764 Query: 2377 KKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQD 2436 + Q +Q L + + E + KI +E+ M ++EE K + M G Sbjct: 765 WEQQRLPEQKEKLWEHEKMQE--QEKIWEQEEKMRDQEE----KMRGQEEKMRG-----Q 813 Query: 2437 QEDSEGDNSK---DPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEP 2493 +E G K +K + K + K W +++ ++ G EE E Sbjct: 814 EEKMRGQEEKMWGQEEKMWGQEEKMWGQEEK-------MWGQEEKMEEKMQGQEEKMREQ 866 Query: 2494 DDQRQVPLGGRRGRKDRERERLEKERTEKERL 2525 +++ RG++++ RE+ EK R ++E++ Sbjct: 867 EEK-------MRGQEEKMREQEEKMRGQEEKI 891 Score = 57.0 bits (136), Expect = 5e-07 Identities = 69/299 (23%), Positives = 138/299 (46%), Gaps = 54/299 (18%) Query: 2267 QDYAAMKAQEKAKKEQEERKHKGALEKEKERL-----QNMDEEEY---DALTEEEKLTFD 2318 Q+ + EK++ + ++ K LE+ K L + EE + + L E+EK Sbjct: 231 QEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRK 290 Query: 2319 RGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKK 2378 + + +E + REQE +E +EK +QE +++E EL+ ++E +++ Sbjct: 291 QEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELR-----------EQEKELRE 339 Query: 2379 SQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEE-LNKKKRNMGDVSMHGLPLVQDQ 2437 + +Q + + + KM E K+ +E+ M +EE L ++++ M + ++DQ Sbjct: 340 QKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQK----MRDQ 395 Query: 2438 ED---SEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPD 2494 E+ + + ++ ++++ + K +E K M ++K M+E + Sbjct: 396 EERMWEQDERLREKEERMREQEKMWEQVEK------MREEKK---------MQEQEKKTR 440 Query: 2495 DQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEE 2553 DQ + K +E ER+ + EK+ E E+ RE+ EK++ EE WE E +E Sbjct: 441 DQEE---------KMQEEERIRER--EKKMREEEETMREQEEKMQKQEENM-WEQEEKE 487 >gi|148746195 trichohyalin [Homo sapiens] Length = 1943 Score = 80.1 bits (196), Expect = 5e-14 Identities = 76/308 (24%), Positives = 147/308 (47%), Gaps = 42/308 (13%) Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKK--RE 2332 +E+ E+ E + + LE++ + + + +EE L EE + + ++ RE ++ +E Sbjct: 1060 EEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQE 1119 Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392 +E+L +E +EK+ +QELERQ E+E V++ ++ ++EEP ++ Q +Q ++ Sbjct: 1120 EEQLLREEREKRRRQELERQYREEE---EVQQEEEQLLREEPEKRRRQELERQYREEEEL 1176 Query: 2393 DVKMETI-----ERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKD 2447 + E + E++ RE+ E+EEL ++KR Q + D D Sbjct: 1177 QQEEEQLLREEQEKRRQERERQYREEEELQRQKRK--------------QRYRDEDQRSD 1222 Query: 2448 PDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGR 2507 Q P+ E ++D + + +Q QL + + + + D Q L G + Sbjct: 1223 LKWQWEPE---KENAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQH---LLGEQQE 1276 Query: 2508 KDRERERL-----EKERTEKERLEREKAE-------RERLEKLRALEERSDWEGEGEEDH 2555 +DRE+ER ++ E+E+LERE+ + + + EK EER + E D Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR 1336 Query: 2556 EGKKEKDL 2563 + ++E+ L Sbjct: 1337 KFREEEQL 1344 Score = 74.7 bits (182), Expect = 2e-12 Identities = 75/340 (22%), Positives = 159/340 (46%), Gaps = 35/340 (10%) Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGA--LEKEKERLQNMDEEEYDALTEEEK 2314 R+ +L ++ + +EK +++++ER+++ L++E+E+L + E+ E + Sbjct: 900 RKEQQLLQEEEEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQ 959 Query: 2315 LTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEP 2374 D+ +QQ + E E+ ++ +EKK ++E E Q+EE++L R ++ ++ E Sbjct: 960 YRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019 Query: 2375 PMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEE-----LNKKKRNMGDVSMH 2429 KK + ++ L + K ER+ RE+ ++EE ++ R ++ Sbjct: 1020 YRKKDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQ 1079 Query: 2430 GLPLVQDQEDSEGDNSKDPDKQLAPKFKTY-----ELTLKDVQNILMYWDRKQGVQLPPA 2484 + Q++ E ++P+K+ + + EL ++ Q + ++++ +L Sbjct: 1080 YRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ 1139 Query: 2485 GMEEAPHEPDDQ---RQVPLGGRRGRKDR----------ERERLEKERTEKERLEREKAE 2531 EE + +++ R+ P RR +R E E+L +E EK R ERE+ Sbjct: 1140 YREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQY 1199 Query: 2532 RE--------RLEKLRALEERSD--WEGEGEEDHEGKKEK 2561 RE R ++ R ++RSD W+ E E+++ + K Sbjct: 1200 REEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNK 1239 Score = 73.2 bits (178), Expect = 6e-12 Identities = 60/305 (19%), Positives = 151/305 (49%), Gaps = 26/305 (8%) Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERLQNMDEE------EYDALTEEEKLTFDRGIQQAL 2325 ++ QE ++ QEE + + L +E++ + +EE E E + +R QQ Sbjct: 281 LERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLR 340 Query: 2326 RERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQ 2385 RE+++R +++L +E +E++ +Q+L R++EE+ ++++++ +Q ++ E +++ Q ++ Sbjct: 341 REQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ--LRREQQLRREQQLRRE 398 Query: 2386 VPPLTKVDVKME-TIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDN 2444 + ++ E + R+ +R + +E+ ++ + L ++QE+ Sbjct: 399 QQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWL 458 Query: 2445 SKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGR 2504 ++ + + + + + +D + R++ ++L EE E ++R+ L R Sbjct: 459 KREEETERHEQERRKQQLKRDQEE----ERRERWLKLE----EEERREQQERREQQL--R 508 Query: 2505 RGRKDRERERLEKERTEKERLEREKAER-------ERLEKLRALEERSDWEGEGEEDHEG 2557 R +++R +RL+++ E+ +R ++E+ ER E+L EE E E E Sbjct: 509 REQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLK 568 Query: 2558 KKEKD 2562 +++++ Sbjct: 569 REQEE 573 Score = 72.8 bits (177), Expect = 8e-12 Identities = 79/304 (25%), Positives = 147/304 (48%), Gaps = 36/304 (11%) Query: 2269 YAAMKAQEKAKKEQ----EERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324 YA QE+ +KEQ EE + E+EK R Q + + EEE+L + +Q Sbjct: 890 YAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQ----YREEEQLQQEE--EQL 943 Query: 2325 LRER--KKREQERLAKEMQEKKLQQELER-QKEEDELKRRVKKGKQGPIKEEPPMKKSQA 2381 LRE K+R QER + ++KKLQQ+ E+ EE E +RR ++ K+ +EE ++ Q Sbjct: 944 LREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQL 1003 Query: 2382 ANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSE 2441 ++ + + + ER+ +++ E+E+L +++R + ++++ E Sbjct: 1004 LREE-----REKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQ------ERERQYRE 1052 Query: 2442 GDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPL 2501 + + ++QL + E + Q + + +++ +Q + EP+ +R+ Sbjct: 1053 EEELQQEEEQLLGE----ERETRRRQELERQYRKEEELQQEEEQL--LREEPEKRRR--- 1103 Query: 2502 GGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEG--EEDHEGKK 2559 R R+ RE E L++E + R EREK R+ LE+ EE E E E+ E ++ Sbjct: 1104 -QERERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRR 1162 Query: 2560 EKDL 2563 ++L Sbjct: 1163 RQEL 1166 Score = 72.4 bits (176), Expect = 1e-11 Identities = 71/291 (24%), Positives = 144/291 (49%), Gaps = 41/291 (14%) Query: 2279 KKEQEERKHKGALEKEKERLQNMDEEE----YDALTEEEKLTFDRGIQQALRERKKREQE 2334 K+E+E +H+ E+ K++L+ EEE + L EEE+ RE+++R ++ Sbjct: 459 KREEETERHE--QERRKQQLKRDQEEERRERWLKLEEEER-----------REQQERREQ 505 Query: 2335 RLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDV 2394 +L +E QE++ +Q L+RQ+EE+ L++R++ +Q ++ E ++ Q ++ + + Sbjct: 506 QLRRE-QEERREQRLKRQEEEERLQQRLRSEQQ--LRREQEERREQLLKREEEKRLEQER 562 Query: 2395 KMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAP 2454 + + ++R+ R + ++EE +++R L ++QE+ K + + Sbjct: 563 REQRLKREQEERRDQLLKREEERRQQR-----------LKREQEERLEQRLKREEVERLE 611 Query: 2455 KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERER 2514 + + E LK + +R+Q + L EE + + Q +R +++ E ER Sbjct: 612 QEERREQRLKREE---PEEERRQQL-LKSEEQEERRQQQLRREQQERREQRLKREEEEER 667 Query: 2515 LE---KERTEKERLEREKAERER---LEKLRALEERSDWEGEGEEDHEGKK 2559 LE K E+ER E+E AE E+ E++++ + W+ E E D K Sbjct: 668 LEQRLKREHEEERREQELAEEEQEQARERIKSRIPKWQWQLESEADARQSK 718 Score = 70.9 bits (172), Expect = 3e-11 Identities = 63/300 (21%), Positives = 147/300 (49%), Gaps = 34/300 (11%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDR-GIQQALR---ER 2328 K +EK ++E+ +R+ + L++E+E+L+ ++ +E +EE+ R +Q LR E Sbjct: 255 KEEEKLQEEEPQRQRE--LQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEE 312 Query: 2329 KKREQERLAKEMQEKKLQQELERQ----KEEDELKRRVKKGKQGPIKEEPPMKKSQAANK 2384 ++REQ+ +E QE++ QQE R+ +E++E + + + +Q + E +++ Q + Sbjct: 313 ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQEEER 372 Query: 2385 QVPPLTKVDV--KMETIERKISV-REQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSE 2441 + L + + + + R+ + REQ + +++L ++++ + + ++ +++ E Sbjct: 373 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEE 432 Query: 2442 GDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPL 2501 K ++ + K + +D W +++ EE ++R+ L Sbjct: 433 RHEQKHEQERREQRLKREQEERRD-------WLKRE---------EETERHEQERRKQQL 476 Query: 2502 GGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEK 2561 ++D+E ER E+ +E RE+ ER + R EER + + +E+ E +++ Sbjct: 477 -----KRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQR 531 Score = 68.6 bits (166), Expect = 2e-10 Identities = 64/291 (21%), Positives = 144/291 (49%), Gaps = 26/291 (8%) Query: 2279 KKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE--QERL 2336 ++E+E RK + L KE+E+LQ + + L EEE+ Q+ RER++ E Q+RL Sbjct: 241 EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRL 300 Query: 2337 AKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKM 2396 +E Q ++ Q+E ER+++++E + + ++ +Q + E +++ Q ++ + + + Sbjct: 301 RREQQLRRKQEE-ERREQQEERREQQERREQQEERREQQLRREQEERRE--QQLRREQEE 357 Query: 2397 ETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKF 2456 E E+++ ++ +++L ++++ + + ++ ++ + ++QL Sbjct: 358 ERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL---- 413 Query: 2457 KTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKD-----RE 2511 E L+ Q + + ++ E HE + + Q + R+D E Sbjct: 414 -RREQQLRREQQLRREQEEER---------HEQKHEQERREQRLKREQEERRDWLKREEE 463 Query: 2512 RERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKD 2562 ER E+ER K++L+R++ E ER E+ LEE E + + + ++E++ Sbjct: 464 TERHEQER-RKQQLKRDQ-EEERRERWLKLEEEERREQQERREQQLRREQE 512 Score = 66.6 bits (161), Expect = 6e-10 Identities = 71/316 (22%), Positives = 147/316 (46%), Gaps = 47/316 (14%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332 + +++ K+EQEER+ + +E+ R Q + E+ + L + K R + L + ++RE Sbjct: 562 RREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLK----REEVERLEQEERRE 617 Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392 Q +E +E++ QQ L+ +++E+ ++++++ +Q + E +K+ + + L + Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQE--RREQRLKREEEEERLEQRLKR- 674 Query: 2393 DVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKD----- 2447 E + REQ ++E+E+ ++R + P Q Q +SE D + Sbjct: 675 -------EHEEERREQELAEEEQEQARERIKSRI-----PKWQWQLESEADARQSKVYSR 722 Query: 2448 PDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGME-----------EAPHEPDDQ 2496 P KQ + + + + + + W ++ E E E Q Sbjct: 723 PRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQ 782 Query: 2497 R---QVPLGGRRGRKDRERERLEKER----TEKERLEREKAERERLEKLRALEE-----R 2544 R + PL +R R+ R ER ++E+ E+E+ +R + RER ++L+ LEE R Sbjct: 783 RLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQR 842 Query: 2545 SDWEGEGEEDHEGKKE 2560 + + +E+ +G +E Sbjct: 843 RERAQQLQEEEDGLQE 858 Score = 66.2 bits (160), Expect = 8e-10 Identities = 70/329 (21%), Positives = 148/329 (44%), Gaps = 33/329 (10%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALT--EEEKLTFDRGIQQALRERKK 2330 + +++ K+++EE + + L E++ + +E L EE++L +R Q+ RE+++ Sbjct: 514 RREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEE 573 Query: 2331 REQERLAKEMQEKKLQQELERQKE---EDELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387 R + L +E E++ QQ L+R++E E LKR + + + E +K+ + ++ Sbjct: 574 RRDQLLKRE--EERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQ 631 Query: 2388 PLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKD 2447 L K + + E ++++ REQ E+ E K+ + L ++E E + +++ Sbjct: 632 QLLKSEEQEERRQQQLR-REQ--QERREQRLKREEEEERLEQRLKREHEEERREQELAEE 688 Query: 2448 PDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGR 2507 +Q + K+ + W + + + P + + QR R Sbjct: 689 EQEQARERIKS--------RIPKWQWQLESEADARQSKVYSRPRKQEGQR---------R 731 Query: 2508 KDRERERLEKERTEKERLEREKAERERLEKLRALEERSD--WEGEGEEDHEGKKEKDLGV 2565 + + E+ + +E + E E+A R++ E+ E+R D W+ + EE E +++ Sbjct: 732 RQEQEEKRRRRESELQWQEEERAHRQQQEE----EQRRDFTWQWQAEEKSERGRQRLSAR 787 Query: 2566 PFLDIQTPDFEGLSWKQALESDKLPKGEQ 2594 P L Q +Q E LP+ E+ Sbjct: 788 PPLREQRERQLRAEERQQREQRFLPEEEE 816 Score = 66.2 bits (160), Expect = 8e-10 Identities = 72/308 (23%), Positives = 156/308 (50%), Gaps = 30/308 (9%) Query: 2267 QDYAAMKAQEKAKKEQEE--RKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324 Q + Q++ ++E++ R+ + L++ +E+ + E + L EE +L QQ Sbjct: 1602 QQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQL 1661 Query: 2325 L--RERKKREQERLAKEMQEKKLQ-QELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQA 2381 R+RK RE+E+L +E +E++L+ QE +R+ E+E + R ++ ++ ++EE +++ + Sbjct: 1662 RHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQEL 1721 Query: 2382 ANK-----QVPPLTKVD-VKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQ 2435 K Q+ T+ + ++ + RKI EQ E+EE +++ L Q Sbjct: 1722 ERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQ 1781 Query: 2436 DQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD 2495 ++E+ + S++ D+ KF+ E ++ ++ QL P + ++ Sbjct: 1782 EREEQQ-LRSQESDR----KFREEEQLRQE----------REEQQLRPQQRDGKYRWEEE 1826 Query: 2496 QRQVPLGGRRGRKDRERE-RLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEED 2554 Q Q+ +R R++R+R+ R E++ +E+ RE+ E + E+ + +ER E + E+ Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQER---ERKLREE 1883 Query: 2555 HEGKKEKD 2562 H +++K+ Sbjct: 1884 HIRRQQKE 1891 Score = 64.7 bits (156), Expect = 2e-09 Identities = 63/292 (21%), Positives = 137/292 (46%), Gaps = 33/292 (11%) Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMD---EEEYDALTEEEKLTFDRGIQQALRERKKR 2331 ++ ++E E + KG EK+++R + D +EE + + + + ++ E +R Sbjct: 208 EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267 Query: 2332 EQERLAKEMQEKKLQ-QELERQKEEDELK-RRVKKGKQGPIKEEPPMKKSQAANKQVPPL 2389 ++E +E Q +KL+ QEL R+++E+E + +R+++ +Q K+E ++ Q ++ Sbjct: 268 QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERRE---- 323 Query: 2390 TKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPD 2449 + E E++ REQ + ++E ++++ L Q++E E ++ + Sbjct: 324 -----QQERREQQEERREQQLRREQEERREQQ---------LRREQEEERREQQLRREQE 369 Query: 2450 KQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKD 2509 ++ + E L+ Q + ++ QL E +R+ L RR ++ Sbjct: 370 EERREQQLRREQQLRREQQLRREQQLRREQQL--------RREQQLRREQQL--RREQQL 419 Query: 2510 RERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEK 2561 R ++L +E+ E+ ++ + ER R EER DW EE ++E+ Sbjct: 420 RREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQER 471 Score = 63.9 bits (154), Expect = 4e-09 Identities = 76/310 (24%), Positives = 146/310 (47%), Gaps = 45/310 (14%) Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERL---QNMDEEEYDALTEEEKLTFDRGIQQALRER 2328 + QE+ +K +EE + E+E++ L Q + +E + EEE+L +R QQ R+ Sbjct: 1423 LSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQE 1482 Query: 2329 KKR----EQERLAKEMQEKKL-QQELERQK-------EEDELKRRVKKGKQGPIKEEPPM 2376 + R E+++L ++ +++K +QEL Q+ EE +L R+ ++ K ++EE + Sbjct: 1483 RDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKF--LQEEQQL 1540 Query: 2377 KKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEE--LNKKKRNMGDVSMHGLPLV 2434 ++ + + + + +RK EQ E+EE L++++R+ Sbjct: 1541 RRQERGQQ----------RRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRR 1590 Query: 2435 QDQ-----EDSEGDNSKDPDKQLAP----KFKTYELTLKDVQNILMYWDRKQGVQLPPAG 2485 Q+Q ED + ++ +QL KF+ E L++ + ++ + L Sbjct: 1591 QEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFL---- 1646 Query: 2486 MEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKE--RLEREKAERERLEKLRALEE 2543 EE P +R+ L R RK RE E+L +E E++ R ER++ RE ++LR E Sbjct: 1647 -EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQER 1705 Query: 2544 RSDWEGEGEE 2553 + E ++ Sbjct: 1706 ERKFLQEEQQ 1715 Score = 63.2 bits (152), Expect = 7e-09 Identities = 70/349 (20%), Positives = 150/349 (42%), Gaps = 58/349 (16%) Query: 2263 LNMAQDYAAMKAQEKAKKEQEERKHKG-------------------ALEKEKERLQNMDE 2303 L Q+ + QE+ +++QE R+ + E+E+ER + Sbjct: 306 LRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLR 365 Query: 2304 EEYDALTEEEKLTFDRGI---------------------------QQALRERKKREQERL 2336 E + E++L ++ + QQ RE++ R +++L Sbjct: 366 REQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQL 425 Query: 2337 AKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKM 2396 +E +E++ +Q+ E+++ E LKR ++ + +EE + Q KQ K D + Sbjct: 426 RREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQ---QLKRDQEE 482 Query: 2397 ETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQL--AP 2454 E ER + + E+ E++E +++ L + +E+ ++QL Sbjct: 483 ERRERWLKLEEEERREQQERREQQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQ 542 Query: 2455 KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERER 2514 + + +L ++ + L R+Q ++ + + +++R+ ++ K + ER Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERR-----QQRLKREQEER 597 Query: 2515 LEK--ERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEK 2561 LE+ +R E ERLE+E+ +RL++ EER + EE E ++++ Sbjct: 598 LEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQ 646 Score = 60.5 bits (145), Expect = 4e-08 Identities = 67/293 (22%), Positives = 136/293 (46%), Gaps = 18/293 (6%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332 + QE+ ++ E R + E + R Q E+E + EE+ ++Q R+R+ E Sbjct: 113 RRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERELAEGEEQSEKQERLEQRDRQRRDEE 172 Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392 R +E QE++ ER+ EE++L + +G EE P + Q +++ L + Sbjct: 173 LWRQRQEWQERE-----ERRAEEEQL-----QSCKGHETEEFP-DEEQLRRRELLELRRK 221 Query: 2393 DVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQL 2452 + E +++ +++ E+EE +KR V +Q++E ++ ++QL Sbjct: 222 G-REEKQQQRRERQDRVFQEEEEKEWRKRE--TVLRKEEEKLQEEEPQRQRELQEEEEQL 278 Query: 2453 APKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRER 2512 K + EL ++ Q R + Q EE E ++R+ R +++R Sbjct: 279 R-KLERQELR-RERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERRE 336 Query: 2513 ERLEKERTEK--ERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDL 2563 ++L +E+ E+ ++L RE+ E R ++LR +E E + + + ++E+ L Sbjct: 337 QQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQL 389 Score = 60.5 bits (145), Expect = 4e-08 Identities = 74/307 (24%), Positives = 140/307 (45%), Gaps = 29/307 (9%) Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERLQNMD-EEEYDALTEEEKLTFDRGIQQALRERKK 2330 ++A+E+ ++EQ + EKE+ R Q + E+E L EEE+L Q+ R ++ Sbjct: 798 LRAEERQQREQRFLPEEE--EKEQRRRQRREREKELQFLEEEEQL------QRRERAQQL 849 Query: 2331 REQERLAKEMQEKKLQQELERQKE-----EDELKRRVKKGKQGPIKEEPPMKKSQAANKQ 2385 +E+E +E QE++ QE R ++ E+E KRR P +E K+ Q ++ Sbjct: 850 QEEEDGLQEDQERRRSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEE 909 Query: 2386 VPPLTKVD---VKMETIERKISVREQTMSEKEEL---NKKKRNMGDVSMH---GLPLVQD 2436 L + + + + ER+ EQ E+E+L ++KR + L Q Sbjct: 910 EEELQREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQK 969 Query: 2437 QEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQ 2496 +E G+ + +Q K E L+ + L+ +R++ + E + Sbjct: 970 EEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQE 1029 Query: 2497 RQVPLGGRRGRKDRERERL-EKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDH 2555 + L R++RE+ RL E+ER +E E ++ E + L + R R + E + ++ Sbjct: 1030 EEQLL-----REEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEE 1084 Query: 2556 EGKKEKD 2562 E ++E++ Sbjct: 1085 ELQQEEE 1091 Score = 58.9 bits (141), Expect = 1e-07 Identities = 72/317 (22%), Positives = 149/317 (47%), Gaps = 41/317 (12%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDE---EEYDALTEEEKLTFDRGIQ-QALRER 2328 +A+ + +K QEE++ +EK R Q D EE L E E+ R + + RE Sbjct: 1306 EAKRRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREE 1365 Query: 2329 KKREQERLAKEMQEKKLQQELERQ----KEEDELK-----RRVKKGKQGPIKEEPPMKKS 2379 + R QE+ K ++E++ + ER+ KEE +L+ +++++ + +EE Sbjct: 1366 ELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSR 1425 Query: 2380 QAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQED 2439 Q +++ + V+ + ERK EQ + ++E ++K R L+Q++E+ Sbjct: 1426 QERDRKFRE-EEQQVRRQERERKFLEEEQQL--RQERHRKFREEEQ-------LLQEREE 1475 Query: 2440 SEGDNSK------DPDKQLA-----PKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEE 2488 + + + ++QL KF+ EL ++ + + ++ QL + Sbjct: 1476 QQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFL----EEEQQLHRQQRQR 1531 Query: 2489 APHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEE---RS 2545 + + Q + G++ R+DR+R+ E+E+ +ER E++ + +ER K R E+ R Sbjct: 1532 KFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQ 1591 Query: 2546 DWEGEGEEDHEGKKEKD 2562 + E + ED + + ++ Sbjct: 1592 EQERKFMEDEQQLRRQE 1608 Score = 58.5 bits (140), Expect = 2e-07 Identities = 66/328 (20%), Positives = 143/328 (43%), Gaps = 39/328 (11%) Query: 2266 AQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQAL 2325 +++ + Q+ +++QE R+ + E+E+ERL+ + E++ E++L + Q+ Sbjct: 636 SEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEE--QEQA 693 Query: 2326 RERKK-----------REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEP 2374 RER K E + ++ + +QE +R+++E E KRR ++ + +EE Sbjct: 694 RERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRR-RRESELQWQEEE 752 Query: 2375 PMKKSQAANKQVPPLT---KVDVKMETIERKISVREQTMSEKE-ELNKKKRNMGDVSMHG 2430 + Q +Q T + + K E +++S R ++E +L ++R + Sbjct: 753 RAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQR--- 809 Query: 2431 LPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAP 2490 + ++E+ E + +++ +F E L+ + + + G+Q Sbjct: 810 --FLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQE 867 Query: 2491 HEPDDQRQVPLGGRRGRK--------------DRERERLEKERTEKERLEREKAERERLE 2536 D + + L R R+ +E++ L++E E +R EREK R+ E Sbjct: 868 QRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQE 927 Query: 2537 KLRALEERSDWEGEG--EEDHEGKKEKD 2562 + EE+ E E E+ E ++ ++ Sbjct: 928 RQYREEEQLQQEEEQLLREEREKRRRQE 955 Score = 58.5 bits (140), Expect = 2e-07 Identities = 72/304 (23%), Positives = 130/304 (42%), Gaps = 51/304 (16%) Query: 2267 QDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEE---EYDALTEEEKLTFDRGIQQ 2323 +D ++ +E+ + ++ER K E+ + R Q +++ + D EE+ G +Q Sbjct: 1623 EDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQ 1682 Query: 2324 ALR-----------ERKKREQERLAKEMQEKK--LQQELERQKEEDELKRRVKKGKQGPI 2370 LR E++ R QER K +QE++ +QELER+ E+E R ++ +Q + Sbjct: 1683 QLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLR--QETEQEQL 1740 Query: 2371 KEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHG 2430 + + +K + P + ++ + +RK EQ E+EE Sbjct: 1741 RRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREE--------------- 1785 Query: 2431 LPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMY-WDRKQGVQLPPAGMEEA 2489 Q E D ++QL + + E L+ Q Y W+ +Q +QL Sbjct: 1786 ----QQLRSQESDRKFREEEQL--RQEREEQQLRPQQRDGKYRWEEEQ-LQL-------- 1830 Query: 2490 PHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEG 2549 E +QR R+ R + + EK R E++ L +E+ ++ R E+ R L E Sbjct: 1831 --EEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQ 1888 Query: 2550 EGEE 2553 + EE Sbjct: 1889 QKEE 1892 Score = 56.6 bits (135), Expect = 6e-07 Identities = 70/317 (22%), Positives = 145/317 (45%), Gaps = 47/317 (14%) Query: 2272 MKAQEKAKKEQEERKHKGALEK---EKERLQNMDEEEYDALTEEEKLTF-DRGIQQAL-R 2326 ++ QE+ +K +E+ E+ E+E+ + + + L EE++L +RG Q+ R Sbjct: 1494 LRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDR 1553 Query: 2327 ERKKREQERLAKEMQEKKL-QQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQ 2385 +RK RE+E+L +E +E++L +QE +R+ +E K R ++ ++ +++E +++ + + Sbjct: 1554 DRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQ- 1612 Query: 2386 VPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDS----- 2440 ++ E +RK EQ + E+EE ++ + P ++ QE Sbjct: 1613 --------LRQER-DRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRRQEREQQLRH 1663 Query: 2441 --------------EGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGM 2486 EG+ + ++ KF+ E L+ + + +Q QL + Sbjct: 1664 DRDRKFREEEQLLQEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQ--QLRRQEL 1721 Query: 2487 EEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSD 2546 E E + RQ + E+E+L ++ ++ LE E+ ER E+ +ER Sbjct: 1722 ERKFREEEQLRQ----------ETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDR 1771 Query: 2547 WEGEGEEDHEGKKEKDL 2563 E E+ + ++E+ L Sbjct: 1772 KFREEEQLRQEREEQQL 1788 Score = 53.9 bits (128), Expect = 4e-06 Identities = 68/299 (22%), Positives = 126/299 (42%), Gaps = 44/299 (14%) Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQAL------RER 2328 Q K Q E + + A+ K + + E++ L E+ DR QQ L ++ Sbjct: 1219 QRSDLKWQWEPEKENAVRDNKVYCKGRENEQFRQL--EDSQLRDRQSQQDLQHLLGEQQE 1276 Query: 2329 KKREQERLAKEMQEKKLQQELERQKEED-ELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387 + REQER + +++ +E + ++EE E KRR +K +EE + + + K+ Sbjct: 1277 RDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKS-----QEEKQLLREEREEKR-- 1329 Query: 2388 PLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKD 2447 + + +RK EQ + E+EE PL + + D + + Sbjct: 1330 -------RRQETDRKFREEEQLLQEREE---------------QPLRRQERDRKFREEEL 1367 Query: 2448 PDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGR 2507 ++ KF E L+ + + +Q QL E+ + D++ + R Sbjct: 1368 RHQEQGRKFLEEEQRLRRQERERKFLKEEQ--QLRCQEREQQLRQDRDRKFREEEQQLSR 1425 Query: 2508 KDRERERLEKE----RTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKD 2562 ++R+R+ E+E R E+ER E+ ++ R E+ R E E EE ++E+D Sbjct: 1426 QERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERD 1484 Score = 52.8 bits (125), Expect = 9e-06 Identities = 42/195 (21%), Positives = 94/195 (48%), Gaps = 39/195 (20%) Query: 2267 QDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALR 2326 Q+ ++ QE +K +EE + L +E E+ Q +E Y + EEE+L +R QQ R Sbjct: 1711 QEEQQLRRQELERKFREEEQ----LRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRR 1766 Query: 2327 E---RKKREQERLAKEMQEKKL-----------QQELERQKEEDELK------------- 2359 + RK RE+E+L +E +E++L +++L +++EE +L+ Sbjct: 1767 QERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEE 1826 Query: 2360 --------RRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMS 2411 +R+++ + + E + + ++ L + + + ER+ +RE+ + Sbjct: 1827 QLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIR 1886 Query: 2412 EKEELNKKKRNMGDV 2426 +++ ++ R +G++ Sbjct: 1887 RQQKEEQRHRQVGEI 1901 Score = 51.2 bits (121), Expect = 3e-05 Identities = 75/355 (21%), Positives = 156/355 (43%), Gaps = 52/355 (14%) Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEK--EKERLQNMDEEEYDALTEEEK 2314 RE +L ++ + + K +EE +H+ K E+E+ E E L EE++ Sbjct: 1339 REEEQLLQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQ 1398 Query: 2315 LTFDRGIQQALRERKKR---EQERLAKEMQEKKLQ--------QELERQKEEDELKRRVK 2363 L QQ ++R ++ E+++L+++ +++K + QE ER+ E+E + R + Sbjct: 1399 LRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQE 1458 Query: 2364 KGKQGPIKEEPPM---KKSQAANKQV--PPLTKVDVKMETIERKISVREQT--------- 2409 + ++ +EE + ++ Q ++Q + + ++ ER REQ Sbjct: 1459 RHRK--FREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERK 1516 Query: 2410 -MSEKEELNKKKRNMGDVSMHGLPLVQD---QEDSEGDNSKDPDKQLAPKFKTYELTLKD 2465 + E+++L++++R + Q+ Q + D ++QL + + +L+ ++ Sbjct: 1517 FLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQE 1576 Query: 2466 VQNILMYWDRK-QGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKER 2524 ++K + + ME+ + Q L R RK RE E+L +ER E+++ Sbjct: 1577 RDRKFRLEEQKVRRQEQERKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQER-EEQQ 1635 Query: 2525 LEREKAERERLE-----------------KLRALEERSDWEGEGEEDHEGKKEKD 2562 L R++ +R+ LE + R E EGEE ++E+D Sbjct: 1636 LHRQERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERD 1690 Score = 50.1 bits (118), Expect = 6e-05 Identities = 64/319 (20%), Positives = 143/319 (44%), Gaps = 55/319 (17%) Query: 2267 QDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALR 2326 ++ + ++ ++E E+R+ + LE++ + + +EE L EE+ Sbjct: 1143 EEEVQQEEEQLLREEPEKRRRQ-ELERQYREEEELQQEEEQLLREEQ------------- 1188 Query: 2327 ERKKREQERLAKEMQEKKLQQELERQKEED---ELKRRVKKGKQGPIKEEPPMKKSQAAN 2383 E++++E+ER +E +E + Q+ +R ++ED +LK + + K+ +++ K + N Sbjct: 1189 EKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGR-EN 1247 Query: 2384 KQVPPLTKVDVK----METIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQED 2439 +Q L ++ + ++ + +++ E+E ++R+ L + +E Sbjct: 1248 EQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEA 1307 Query: 2440 SEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRK--QGVQLPPAGMEEAPHEPDDQR 2497 D +KQL + + + ++ DRK + QL ++E +P ++ Sbjct: 1308 KRRDRKSQEEKQLLREEREEKRRRQET-------DRKFREEEQL----LQEREEQPLRRQ 1356 Query: 2498 QVPLGGRRGRKDRERERLEKER-----TEKERLEREKAERERL---------EKLRALEE 2543 + R RK RE E +E+ E++RL R++ ER+ L E+ + L + Sbjct: 1357 E------RDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQ 1410 Query: 2544 RSDWEGEGEEDHEGKKEKD 2562 D + EE ++E+D Sbjct: 1411 DRDRKFREEEQQLSRQERD 1429 Score = 45.4 bits (106), Expect = 0.001 Identities = 34/127 (26%), Positives = 69/127 (54%), Gaps = 17/127 (13%) Query: 2263 LNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMD------EEEYDALTEEEKLT 2316 L ++ +++QE +K +EE + + E+++ R Q D EE+ +E++L Sbjct: 1779 LRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLEEQEQRLR 1838 Query: 2317 FDRGIQQ------ALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQ--- 2367 +R Q A +E+ +RE++ L +E +E+K +QE ER+ E+ ++R+ K+ ++ Sbjct: 1839 QERDRQYRAEEQFATQEKSRREEQELWQE-EEQKRRQERERKLREEHIRRQQKEEQRHRQ 1897 Query: 2368 -GPIKEE 2373 G IK + Sbjct: 1898 VGEIKSQ 1904 Score = 39.7 bits (91), Expect = 0.078 Identities = 22/102 (21%), Positives = 58/102 (56%), Gaps = 9/102 (8%) Query: 2273 KAQEKAKKEQEERKHKGA-----LEKEKERLQNMDEEEYDA----LTEEEKLTFDRGIQQ 2323 + +++ + +Q + K++ LE++++RL+ + +Y A T+E+ ++ + Q Sbjct: 1807 REEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQ 1866 Query: 2324 ALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKG 2365 +++++E+ER +E ++ Q+E +R ++ E+K + KG Sbjct: 1867 EEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQEGKG 1908 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 75.1 bits (183), Expect = 2e-12 Identities = 68/284 (23%), Positives = 143/284 (50%), Gaps = 46/284 (16%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332 K +E+ K++++E K EK +E+ + + E+E +EEK+ I++ E K++E Sbjct: 404 KIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE---EEKRQE 460 Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392 QE + ++ ++ + Q+E+ RQKE+ + +++K +EE ++ + + Q + + Sbjct: 461 QEEMWRQEEKIREQEEIWRQKEKMHEQEKIRK------QEEKVWRQEEKMHDQEEKIREQ 514 Query: 2393 DVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQL 2452 + KM E KI +E+ + E+EE +++ M +Q+QE+ G+ + +Q Sbjct: 515 EEKMWRQEEKIREQEEKIREQEEKIREQEEM----------MQEQEEKMGEQEEKMQEQ- 563 Query: 2453 APKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRER 2512 K + E +++ + + ++K+ ++ EE E ++ K RE+ Sbjct: 564 -EKMRRQEEKIREQEEKIR--EQKEKIR----EQEEKIWEQEE------------KIREQ 604 Query: 2513 ERLEKERTEK------ERLEREKAERERLEKLRALEERSDWEGE 2550 E + +E+ EK + E+E+ +E+ EK+R EE+ WE E Sbjct: 605 EEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKM-WEQE 647 Score = 70.9 bits (172), Expect = 3e-11 Identities = 68/295 (23%), Positives = 147/295 (49%), Gaps = 51/295 (17%) Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKR 2331 M QEK ++++E+R+ + + ++++R E+E +EEK+ R ++ +RE++K+ Sbjct: 386 MHEQEKIREQEEKRQEEEKIREQEKR----QEQEAKMWRQEEKI---REQEEKIREQEKK 438 Query: 2332 EQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPI-KEEPPMKKSQAANKQVPPLT 2390 + K +++K+++E +RQ++E+ ++ K +Q I +++ M + + KQ + Sbjct: 439 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVW 498 Query: 2391 KVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDK 2450 + + KM E KI +E+ M +EE +++QE+ Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEK-----------------IREQEE----------- 530 Query: 2451 QLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDR 2510 K + E +++ + ++ + K G Q EE E + R+ R ++++ Sbjct: 531 ----KIREQEEKIREQEEMMQEQEEKMGEQ------EEKMQEQEKMRRQEEKIRE-QEEK 579 Query: 2511 ERERLEKERTEKERL-EREKAERERLEKLRALEERSDWEGEGE--EDHEGKKEKD 2562 RE+ EK R ++E++ E+E+ RE+ E ++ EE+ WE E + E E +E++ Sbjct: 580 IREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKM-WEQEEKMCEQEEKMQEQE 633 Score = 63.5 bits (153), Expect = 5e-09 Identities = 61/320 (19%), Positives = 156/320 (48%), Gaps = 21/320 (6%) Query: 2263 LNMAQDYAAMKAQEKAKK------EQEE--RKHKGALEKEKERLQNMDE---EEYDALTE 2311 LN Q+ + +EK ++ EQEE R+ + + +++E+++ +E E+ + + Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353 Query: 2312 EEKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQE-LERQKEEDELKRRVKKGKQGPI 2370 +E++ +++ + E E+E +E++EK +QE + Q+E+ + + ++++ ++ Sbjct: 354 QEEMMWEKEEKMRRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 413 Query: 2371 KEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHG 2430 +E ++ + +Q + + + KM E KI +E+ E++ +++ + + Sbjct: 414 QEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 473 Query: 2431 LPLVQDQEDSEGDNS---KDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGME 2487 + Q++ + K +K + K ++ K + W +++ ++ + Sbjct: 474 QEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIR 533 Query: 2488 EAPHEPDDQRQV--PLGGRRGRKDRERERLEKERTEKERL-EREKAERERLEKLRALEER 2544 E + +Q ++ + G ++ + + EK R ++E++ E+E+ RE+ EK+R EE+ Sbjct: 534 EQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEK 593 Query: 2545 SDWEGEGE--EDHEGKKEKD 2562 WE E + E E +E++ Sbjct: 594 I-WEQEEKIREQEEMMQEQE 612 Score = 60.8 bits (146), Expect = 3e-08 Identities = 57/283 (20%), Positives = 133/283 (46%), Gaps = 24/283 (8%) Query: 2283 EERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQE 2342 EE K K A +EK +L ++ E +E K +R +++ + E + L KE+Q Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276 Query: 2343 KKLQQELERQKEEDELKRRVKKGKQGPI--KEEPPMKKSQAANKQVPPLTKVDVKMETIE 2400 + +L+ Q EE+EL R+ + ++ + +EE + + +Q + + + K+ E Sbjct: 277 --VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334 Query: 2401 RKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYE 2460 K+ +E+ M EKEE +++ M +++ + ++ + K + E Sbjct: 335 EKMRRQEEMMWEKEEKMRRQEEM-----------MWEKEEKMRRLEEMMWEKEEKIRELE 383 Query: 2461 LTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERT 2520 + + + I +++Q EE ++RQ ++++ RE+ EK R Sbjct: 384 EKMHEQEKIREQEEKRQ---------EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 434 Query: 2521 EKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDL 2563 +++++ R++ + EK+R E+R + E ++ + ++++++ Sbjct: 435 QEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 477 Score = 54.3 bits (129), Expect = 3e-06 Identities = 44/165 (26%), Positives = 83/165 (50%), Gaps = 25/165 (15%) Query: 2272 MKAQEKAKKEQE-----ERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALR 2326 M QEK +K++E E K EK +E+ + M +E +EEK+ + Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIRE--------Q 535 Query: 2327 ERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIK-----------EEPP 2375 E K REQE + +E +EK +QE E+ +E+++++R+ +K ++ K EE Sbjct: 536 EEKIREQEEMMQEQEEKMGEQE-EKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKI 594 Query: 2376 MKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKK 2420 ++ + +Q + + + KM E K+ +E+ M E+EE +++ Sbjct: 595 WEQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 639 Score = 49.7 bits (117), Expect = 8e-05 Identities = 35/164 (21%), Positives = 95/164 (57%), Gaps = 10/164 (6%) Query: 2272 MKAQEKAKKEQEER--KHKGALEKEKERLQNMDE---EEYDALTEEEKLTFDRGIQQALR 2326 M QE+ +EQEE+ + + + +++E+++ +E E+ + + E+E+ ++ + + Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQ 563 Query: 2327 ERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQV 2386 E+ +R++E++ +E +EK +Q+ + +++E+++ + +K ++ +EE ++ + +Q Sbjct: 564 EKMRRQEEKI-REQEEKIREQKEKIREQEEKIWEQEEKIRE---QEEMMQEQEEKMWEQE 619 Query: 2387 PPLTKVDVKMETIERKISVREQTMSEKE-ELNKKKRNMGDVSMH 2429 + + + KM+ E K+ +E+ M E+E L +++ M + H Sbjct: 620 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 663 Score = 48.5 bits (114), Expect = 2e-04 Identities = 25/98 (25%), Positives = 59/98 (60%), Gaps = 5/98 (5%) Query: 2267 QDYAAMKAQEKAKKEQEE--RKHKGALEKEKERLQNMDE---EEYDALTEEEKLTFDRGI 2321 Q+ M+ QE+ +EQEE R+ K + +++E++ +E E+ + + E+E+ +++ Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMWEQEE 620 Query: 2322 QQALRERKKREQERLAKEMQEKKLQQELERQKEEDELK 2359 + +E K +EQE + +EK +QE+ +++E++++ Sbjct: 621 KMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 658 >gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 828 Score = 73.9 bits (180), Expect = 4e-12 Identities = 86/367 (23%), Positives = 160/367 (43%), Gaps = 38/367 (10%) Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324 M + M+ QEK +EQE+ + EKE + + E+E +EEK+ + Sbjct: 271 MREQEEKMRRQEKRLREQEKELREQ--EKELREQKKLREQEEQMQEQEEKMWEQEEKMRE 328 Query: 2325 LRERKKREQERL---AKEM--QEKKLQQELERQKEEDELKRRVKKGKQGPIK---EEPPM 2376 E+ R++ERL K+M QE+K++ + ER E+DE R ++ + K +E M Sbjct: 329 QEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKM 388 Query: 2377 KKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEEL----------------NKKK 2420 ++ + ++ + + + M E K+ +E+ M E+EE +K Sbjct: 389 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 448 Query: 2421 RNMGDVSMHGLPLVQDQEDSEGDNSK--DPDKQLAPKFKTYELTLKDVQNILMYWDRKQG 2478 + + ++DQE+ G K +K + + +E K WD+++ Sbjct: 449 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 508 Query: 2479 VQLPPAGMEEAPHEPDDQR---QVPLGGRRGRKDRERERL-----EKERTEKERLEREKA 2530 + + E +Q+ Q R +K +E+E+ EK R E+ EREK Sbjct: 509 MWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKK 568 Query: 2531 ERERLEKLRALEERSDWEGEGEEDHEGKK-EKDLGVPFLDIQTPDFEGLSWKQALESDKL 2589 RE E +R EE+ + E + E K E++ + + + + E W+Q E DK+ Sbjct: 569 MREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE-EEDKM 627 Query: 2590 PKGEQIL 2596 + E+++ Sbjct: 628 QEQEEMM 634 Score = 68.2 bits (165), Expect = 2e-10 Identities = 75/304 (24%), Positives = 156/304 (51%), Gaps = 32/304 (10%) Query: 2272 MKAQEKAKKEQEE--RKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERK 2329 M QE+ +EQE+ RK + + +++ERL+ E+E +EEK+ R ++ LRE++ Sbjct: 236 MWRQEEELREQEKKIRKQEEKMWRQEERLR---EQEGKMREQEEKM---RRQEKRLREQE 289 Query: 2330 K--REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387 K REQE+ +E Q+K +QE + Q++E+++ + +K ++ +EE ++ + +Q Sbjct: 290 KELREQEKELRE-QKKLREQEEQMQEQEEKMWEQEEKMRE---QEEKMWRQEERLWEQEK 345 Query: 2388 PLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKD 2447 + + + KM E ++ +++ + EKEE +++ M + Q+++ E + ++ Sbjct: 346 QMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWE---------QEEKMQEEERIRE 396 Query: 2448 PDKQLAPKFKTY----ELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGG 2503 +K++ + +T E K +N+ +++ Q P E+ + Q Q Sbjct: 397 REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIW 456 Query: 2504 RRGRKDRERERL---EKERTEKERL-EREKAERERLEKLRALEERS-DWEGEGEEDHEGK 2558 + K R++E + EK+ +E++ E+E E+ EK+R E++ D E E E Sbjct: 457 EQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERL 516 Query: 2559 KEKD 2562 +EK+ Sbjct: 517 REKE 520 Score = 67.0 bits (162), Expect = 5e-10 Identities = 75/318 (23%), Positives = 145/318 (45%), Gaps = 37/318 (11%) Query: 2265 MAQDYAAMKAQEKAKKEQEERK-HKGALEKEKERL---QNMDEEEYDALTEEEKLTFDRG 2320 M + M+ QE+ EQEE++ + L ++KE+L + M E+E +EEK+ Sbjct: 408 MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE 467 Query: 2321 I----QQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPM 2376 + ++ R+ K REQE E +EK QE + +E+ + + ++ ++E+ Sbjct: 468 MWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDER-----LREKEER 522 Query: 2377 KKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQD 2436 + Q Q + + K + E+K +E+ M E+E + ++++ M + ++++ Sbjct: 523 MREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEE----EMMRE 578 Query: 2437 QEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQ 2496 QE+ + +K + K +E K + W++++ M E E Q Sbjct: 579 QEEKMQEQE---EKMREQEEKMWEQEEKMQEQEEKMWEQEEK-------MWEQEEEDKMQ 628 Query: 2497 RQVPLGGRRGRKDRERERLEKERTEKERLEREKA--ERERL----EKLRALEERSDWE-- 2548 Q + + K +E+E E+ EK R + EK + E++ EK+R EE+ + Sbjct: 629 EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEE 688 Query: 2549 --GEGEEDHEGKKEKDLG 2564 E EE G++EK G Sbjct: 689 KMREQEEKMRGQEEKMWG 706 Score = 66.2 bits (160), Expect = 8e-10 Identities = 61/293 (20%), Positives = 146/293 (49%), Gaps = 33/293 (11%) Query: 2267 QDYAAMKAQEKAKKEQEE-RKHKGALEKEKERLQNMDEEEYDA----LTEEEKLTFDRGI 2321 +D M QEK QE+ R+ + + +++E++++ +++ +D ++E+L R Sbjct: 463 RDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERL---REK 519 Query: 2322 QQALRERKK--REQERLAKEM----QEKKLQQELERQKEEDELKRRVKKGKQGPI----K 2371 ++ +RE+KK +++E++ +E QEKK + E+ +EE+ ++ R KK ++ + Sbjct: 520 EERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQ 579 Query: 2372 EEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGL 2431 EE ++ + +Q + + + KM+ E K+ +E+ M E+EE +K Sbjct: 580 EEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDK------------- 626 Query: 2432 PLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPH 2491 +Q+QE+ + + +Q ++ E + + + ++ QG + EE Sbjct: 627 --MQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQ 684 Query: 2492 EPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEER 2544 +++ + RG++++ + EK ++E++ ++ RE+ E++R +E+ Sbjct: 685 GQEEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEK 737 Score = 65.9 bits (159), Expect = 1e-09 Identities = 66/302 (21%), Positives = 143/302 (47%), Gaps = 31/302 (10%) Query: 2272 MKAQEKAKKEQEER----KHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRE 2327 M+ QE+ EQEE+ + EK+ R + M E+E +EEK+ E Sbjct: 448 MQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEE 507 Query: 2328 RKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387 R + ERL ++ + + Q+++ +Q+E+ +++ ++ ++ +E M++ + ++ Sbjct: 508 RMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREK 567 Query: 2388 PLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKD 2447 + + + M E K+ +E+ M E+EE ++ +Q+QE+ + + Sbjct: 568 KMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEK----------MQEQEEKMWEQEE- 616 Query: 2448 PDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGM---EEAPHEPDDQRQVPLGGR 2504 K E K + M W++++ +Q M EE E +++ + Sbjct: 617 -------KMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 669 Query: 2505 RGRKDRERERLEKERTEKERL-EREKAERERLEKLRALEERSDWEGE----GEEDHEGKK 2559 +G++++ RE+ EK + ++E++ E+E+ R + EK+ EE+ W E G+E+ K+ Sbjct: 670 QGQEEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEEKM-WGQEEKMWGQEEMREKE 728 Query: 2560 EK 2561 E+ Sbjct: 729 ER 730 Score = 60.5 bits (145), Expect = 4e-08 Identities = 45/197 (22%), Positives = 99/197 (50%), Gaps = 21/197 (10%) Query: 2265 MAQDYAAMKAQEKAKKEQEER--KHKGALEKEKERLQNMDE-----EEYDALTEEEKLTF 2317 M + M+ QE+ +EQEE+ + + +++++E++ +E EE D + E+E++ + Sbjct: 576 MREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMW 635 Query: 2318 DRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKK--GKQGPIKEEPP 2375 ++ + +E K EQE +E +EK +QE + Q +E++++ + +K G++ ++E+ Sbjct: 636 EQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQEEKMREQEE 695 Query: 2376 MKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQ 2435 + Q + KM E K+ +E+ M +EE+ +K+ + D + Sbjct: 696 KMRGQ------------EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLP 743 Query: 2436 DQEDSEGDNSKDPDKQL 2452 + E+ + P K L Sbjct: 744 EHEERCSEPCLPPSKVL 760 Score = 54.7 bits (130), Expect = 2e-06 Identities = 68/295 (23%), Positives = 135/295 (45%), Gaps = 52/295 (17%) Query: 2283 EERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRG------IQ-QALRERKKREQER 2335 EE K K A +EK RL ++ E +E K +R +Q L+E R++E Sbjct: 183 EELKKKNAELQEKLRLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQEEMWRQEEE 242 Query: 2336 LAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVK 2395 L + QEKK++++ E+ ++E R ++G ++E+ + Q + + Sbjct: 243 LRE--QEKKIRKQEEKMWRQEERLRE----QEGKMREQEEKMRRQ------------EKR 284 Query: 2396 METIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPK 2455 + E+++ +E+ + E+++L +++ M Q+QE+ + + +Q K Sbjct: 285 LREQEKELREQEKELREQKKLREQEEQM-----------QEQEEKMWEQEEKMREQ-EEK 332 Query: 2456 FKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERL 2515 E L + + + ++K Q EE E D++ + + + RE+E++ Sbjct: 333 MWRQEERLWEQEKQMREQEQKMRDQ------EERMWEQDERLR-----EKEERMREQEKM 381 Query: 2516 ---EKERTEKERL-EREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVP 2566 E++ E+ER+ EREK RE E +R EE+ + E + E K+ + +P Sbjct: 382 WEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLP 436 Score = 51.2 bits (121), Expect = 3e-05 Identities = 52/237 (21%), Positives = 107/237 (45%), Gaps = 15/237 (6%) Query: 2265 MAQDYAAMKAQEKAKKEQE-----ERKHKGALEKEKERLQNMDEEEYDALTEEEKL-TFD 2318 M ++ + ++K ++E+E E K + EK +E+ + M E+E +EEK+ + Sbjct: 556 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQE 615 Query: 2319 RGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKK 2378 + + E K +EQE + E +EK +QE + ++E++++ + +K ++ +EE + Sbjct: 616 EKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMRE---QEEKMQGQ 672 Query: 2379 SQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQE 2438 + +Q + + KM E K+ +E+ M +EE K + M G ++++E Sbjct: 673 EEKMREQEEKMQGQEEKMREQEEKMRGQEEKMWGQEE----KMWGQEEKMWGQEEMREKE 728 Query: 2439 DSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD 2495 + D + ++L + +L V+ PAG E P D Sbjct: 729 ERIRDQKEKMQERLPEHEERCSEPCLPPSKVLCNMSHTGSVE--PAGGEAGEGSPQD 783 >gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] Length = 793 Score = 73.9 bits (180), Expect = 4e-12 Identities = 83/366 (22%), Positives = 156/366 (42%), Gaps = 67/366 (18%) Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324 +A + A ++A+EKA ++ ER+ E E + M EEE A E +++ + Sbjct: 288 IADERARIEAEEKAAAQERERR-------EAEERERMREEEKRAAEERQRIKEEEKRAAE 340 Query: 2325 LRERKKREQERLAKEMQ-----EKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKS 2379 R+R K E++R A+E Q EK+ +E +R + E+E K +V++ K+ EE K Sbjct: 341 ERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEE----KK 396 Query: 2380 QAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQED 2439 A + + +K E +E+KI E + +N+KK + L +++ Sbjct: 397 HA-------MQETKIKGEKVEQKI--------EGKWVNEKKAQEDKLQTAVLKKQGEEKG 441 Query: 2440 SEGDNSKDPDKQLAPKFKTYELTLKDV-------QNILMYWDRKQGVQ------------ 2480 ++ ++ ++ P FK E+ + + + + + DRK+G Sbjct: 442 TKVQAKREKLQEDKPTFKKEEIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTH 501 Query: 2481 ---------LPPAGM--------EEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKE 2523 P G E AP +R L RRG + E K++ ++ Sbjct: 502 KLKHTENTFSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEA 561 Query: 2524 RLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQA 2583 LE E+ +++R E+ + LEE + E D + ++E++ +I+ E +Q Sbjct: 562 ALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRLKEEIERRRAEAAEKRQK 621 Query: 2584 LESDKL 2589 + D L Sbjct: 622 MPEDGL 627 Score = 60.1 bits (144), Expect = 6e-08 Identities = 72/312 (23%), Positives = 139/312 (44%), Gaps = 33/312 (10%) Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQE 2334 QE+ +++QEE ++ + QN +E +A T + + A ER R +E Sbjct: 47 QERLRQKQEEESLGQVTDQVEVNAQNSVPDE-EAKTTTTNTQVEGDDEAAFLERLARREE 105 Query: 2335 RLAKEMQEKKLQQELERQKEED------ELKRRVKKGKQGPIKEEPPMKKSQAANKQ--- 2385 R ++K+LQ+ LERQKE D L ++ + + E K+ ++ ++Q Sbjct: 106 R-----RQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERY 160 Query: 2386 ----VPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSE 2441 +TK K + + + + +E E+EE K KR G + + + ++ +++ +E Sbjct: 161 EIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKR--GSIGENQVEVMVEEKTTE 218 Query: 2442 GDNS----KDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQR 2497 + Q++ + E + + + + ++ + A E A E +++ Sbjct: 219 SQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERE 278 Query: 2498 QVPLGGRRGRKDRERERLEKER----TEKERLEREKAERERLEKLRALEER---SDWEGE 2550 ++ + D ER R+E E E+ER E E+ ER R E+ RA EER + E Sbjct: 279 RIKAEQDKKIAD-ERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQRIKEEEKR 337 Query: 2551 GEEDHEGKKEKD 2562 E+ + KE++ Sbjct: 338 AAEERQRIKEEE 349 Score = 58.2 bits (139), Expect = 2e-07 Identities = 75/358 (20%), Positives = 149/358 (41%), Gaps = 75/358 (20%) Query: 2268 DYAAMKAQEKAKKEQEERKHKGALEKEKE---------------RLQNMDEEEYDALTEE 2312 D AA + ++E+ +++ + ALE++KE R+QN D E + +E Sbjct: 92 DEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQN-DTAENETTEKE 150 Query: 2313 EKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKE 2372 EK ++ +ER + E+ + +K ++ E K+ED+ K +E Sbjct: 151 EK-------SESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEE---------EE 194 Query: 2373 EPPMKKSQAANKQVPPLTK---VDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMH 2429 E K+ QV + + + + ET+ + + + E ++ ++++ ++S H Sbjct: 195 EEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHH 254 Query: 2430 GLPLVQDQEDSEGDNSK-----------DPDKQLAPKFKTYELTLKDVQNILMYWDRKQG 2478 +D+E +E + ++ + DK++A + E K Sbjct: 255 EKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEK-------------- 300 Query: 2479 VQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERL------EREKAER 2532 A E E +++ ++ +R ++R+R + E++R +ER +R ER Sbjct: 301 ----AAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEER 356 Query: 2533 ERL--EKLRALEERSDWEGEGEED---HEGKKEKDLGVPFLDIQTPDFEGLSWKQALE 2585 +R+ E+ RA EER E EE E K+ K L +Q +G +Q +E Sbjct: 357 QRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIE 414 Score = 50.8 bits (120), Expect = 3e-05 Identities = 62/298 (20%), Positives = 122/298 (40%), Gaps = 53/298 (17%) Query: 2261 YILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRG 2320 Y N +D K ++K K+E+EE K K E + ++E+ ++ E ++ G Sbjct: 172 YQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNG 231 Query: 2321 IQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQ 2380 Q E K+E+ER E+ + +K E+E K R + + EE K++ Sbjct: 232 --QISSEEPKQEEER------EQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAE 283 Query: 2381 AANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDS 2440 K +++ E K + +E+ E EE + + + + Sbjct: 284 QDKKIADERARIEA-----EEKAAAQERERREAEERERMREE------------EKRAAE 326 Query: 2441 EGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVP 2500 E K+ +K+ A + +Q ++ EE ++++++ Sbjct: 327 ERQRIKEEEKRAA--------------------EERQRIK------EEEKRAAEERQRIK 360 Query: 2501 LGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGK 2558 +R ++R+R R E+E EK ++E +K ++ EK A++E + E+ EGK Sbjct: 361 EEEKRAAEERQRARAEEE--EKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQKIEGK 416 Score = 49.3 bits (116), Expect = 1e-04 Identities = 51/215 (23%), Positives = 93/215 (43%), Gaps = 24/215 (11%) Query: 2276 EKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRG-----IQQALRERKK 2330 E K+ +E R+ +G E E E + + +++ +A E E+L R +++ + RK+ Sbjct: 531 EAGKRLEELRRRRG--ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQ 588 Query: 2331 REQERLAKEMQEK-KLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPL 2389 E +R +E +EK +L++E+ER++ E KR+ K + G ++ P K + Sbjct: 589 EEADRKLREEEEKRRLKEEIERRRAEAAEKRQ-KMPEDGLSDDKKPFKCFTPKGSSL--- 644 Query: 2390 TKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPD 2449 K++ + E + + + +K K VS L Q EG S P Sbjct: 645 -KIEERAEFLNKSV--------QKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPT 695 Query: 2450 KQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPA 2484 K P + + V+NI W++ P A Sbjct: 696 K---PAASDLPVPAEGVRNIKSMWEKGNVFSSPTA 727 >gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens] Length = 570 Score = 72.4 bits (176), Expect = 1e-11 Identities = 66/285 (23%), Positives = 135/285 (47%), Gaps = 24/285 (8%) Query: 2281 EQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEM 2340 +Q+E K EK +ER + + E+E +EEK+ R QE + E Sbjct: 284 QQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKM---------------RRQEEMMWEK 328 Query: 2341 QEK-KLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETI 2399 +EK + Q+E+ +KEE + K +Q I+E+ ++ + ++ + + KM Sbjct: 329 EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQ 388 Query: 2400 ERKISVREQTMSEKEE-LNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDK--QLAPKF 2456 E KI +E+ + E+EE + +++ MG+ ++ ++ E + +K + K Sbjct: 389 EEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKI 448 Query: 2457 KTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLE 2516 + E +++ + ++ + K G Q +EA + +++ R+ K RE+E+ Sbjct: 449 REQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKM----RRQEEKIREQEKKI 504 Query: 2517 KERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEK 2561 +E+ EK R E+E+ +E+ EK+ EE+ + E ++ E K + Sbjct: 505 REQEEKIR-EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 548 Score = 68.6 bits (166), Expect = 2e-10 Identities = 67/290 (23%), Positives = 145/290 (50%), Gaps = 43/290 (14%) Query: 2272 MKAQEKAKKEQEE--RKHKGALEKEKERLQNMDEE--EYDALTEEEKLTFDRGIQQALRE 2327 M+ QE+ E+EE R+ + + +++E+++ ++E+ E + + E+E+ R ++ +RE Sbjct: 318 MRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEE---KRQEEEKIRE 374 Query: 2328 RKKREQERLAKEMQEKKLQQELERQKEEDEL--KRRVKKGKQGPIKEEPPMKKSQAANKQ 2385 ++KR+++ QE+K++++ E+ +E++E+ ++ K G+Q EE ++ + +Q Sbjct: 375 QEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQ----EEKMWEQEEEMQEQ 430 Query: 2386 VPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNS 2445 + + + K+ E+KI +E+ + E+EE+ +Q+QE+ G+ Sbjct: 431 EEKMRRQEEKIREQEKKIREQEEKIREQEEM-----------------MQEQEEKMGEQE 473 Query: 2446 KDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRR 2505 +Q A K + E ++ + + ++K Q EE E ++ Q + Sbjct: 474 GKMCEQEA-KMQEQEEKMRRQEEKIREQEKKIREQ------EEKIREQEEMMQ-----EQ 521 Query: 2506 GRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDH 2555 K E+E E+ EK + + EK R+ EK+R E R + E ++H Sbjct: 522 EEKMWEQEEKMCEQEEKMQEQEEKMRRQE-EKMREQEVRLRQQEEKMQEH 570 Score = 65.9 bits (159), Expect = 1e-09 Identities = 67/289 (23%), Positives = 133/289 (46%), Gaps = 26/289 (8%) Query: 2283 EERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQE 2342 EE K K A +EK +L ++ E +E K +R +++ + E + L KE+Q Sbjct: 205 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 264 Query: 2343 KKLQQELERQKEEDELKRRVKKGKQGPI--KEEPPMKKSQAANKQVPPLTKVDVKMETIE 2400 + +L+ Q EE+EL R+ + ++ + +EE ++ + +Q + + + KM E Sbjct: 265 --VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQE 322 Query: 2401 RKISVREQTMSEKEEL---NKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFK 2457 + +E+ M +EE+ ++K + MH +++QE+ + K +++ Sbjct: 323 EMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQE------ 376 Query: 2458 TYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD--QRQVPLGGRRGRKDRERERL 2515 K + W +++ ++ EE E ++ Q Q G + K E+E Sbjct: 377 ------KRQEQEAKMWRQEEKIR----EQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEE 426 Query: 2516 EKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLG 2564 +E+ EK R + EK RE+ +K+R EE+ + E ++ E K + G Sbjct: 427 MQEQEEKMRRQEEKI-REQEKKIREQEEKIREQEEMMQEQEEKMGEQEG 474 Score = 48.5 bits (114), Expect = 2e-04 Identities = 35/145 (24%), Positives = 77/145 (53%), Gaps = 10/145 (6%) Query: 2265 MAQDYAAMKAQEKAKKEQEE--RKHKGALEKEKERLQNMDE---EEYDALTEEEKLTFDR 2319 M + M+ QE+ +EQE+ R+ + + +++E +Q +E E+ + E+E ++ Sbjct: 427 MQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQ 486 Query: 2320 GIQQALRERKKREQERLAKEMQEK-KLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKK 2378 + +E K REQE+ +E +EK + Q+E+ +++EE ++ K +Q EE ++ Sbjct: 487 EEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQ----EEKMQEQ 542 Query: 2379 SQAANKQVPPLTKVDVKMETIERKI 2403 + +Q + + +V++ E K+ Sbjct: 543 EEKMRRQEEKMREQEVRLRQQEEKM 567 Score = 45.1 bits (105), Expect = 0.002 Identities = 23/97 (23%), Positives = 57/97 (58%), Gaps = 6/97 (6%) Query: 2265 MAQDYAAMKAQEKAKKEQEE--RKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQ 2322 M + A M+ QE+ + QEE R+ + + +++E+++ +E + E+E+ +++ + Sbjct: 476 MCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEE----MMQEQEEKMWEQEEK 531 Query: 2323 QALRERKKREQERLAKEMQEKKLQQELERQKEEDELK 2359 +E K +EQE + +EK +QE+ +++E++++ Sbjct: 532 MCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQEEKMQ 568 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 70.9 bits (172), Expect = 3e-11 Identities = 69/299 (23%), Positives = 146/299 (48%), Gaps = 32/299 (10%) Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324 M + M +E+ +E EE+ H E+EK R Q +E + + E+EK ++ + Sbjct: 426 MRRQEEMMWEKEEKIRELEEKMH----EQEKIREQEEKRQEEEKIREQEKRQ-EQEAKMW 480 Query: 2325 LRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPI-KEEPPMKKSQAAN 2383 +E K REQE +E +EK +QE E+ E+++++ K+ +Q + ++E +++ + Sbjct: 481 RQEEKIREQEEKIREQEEKMWRQE-EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIW 539 Query: 2384 KQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGD 2443 +Q + + + K+ E K+ +E+ M ++EE K R + +++QE+ Sbjct: 540 RQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEE---KIREQEEKVWRQEEKIREQEE---- 592 Query: 2444 NSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGG 2503 K + E +++ + + + K G Q EE E +++ Q Sbjct: 593 -----------KIREQEEKIREQEEMTQEQEEKMGEQ------EEKMCEQEEKMQEQEEK 635 Query: 2504 RRGRKDRERERLEKERTEKERL-EREKAERERLEKLRALEERSDWEGEGEEDHEGKKEK 2561 R ++++ RE+ +K R ++E++ E+E+ +E+ EK+ EE+ + E ++ E K + Sbjct: 636 MRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 694 Score = 66.6 bits (161), Expect = 6e-10 Identities = 62/292 (21%), Positives = 138/292 (47%), Gaps = 10/292 (3%) Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKR 2331 + Q++ K ++E K + EK +E+ + + E+E +EEK+ + E+ +R Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 414 Query: 2332 EQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTK 2391 ++E + ++ ++ + Q+E+ +KEE + K +Q I+E+ ++ + ++ + Sbjct: 415 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 474 Query: 2392 VDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQ 2451 + KM E KI +E+ + E+EE K + +H ++++E + ++ Sbjct: 475 QEAKMWRQEEKIREQEEKIREQEE----KMWRQEEKIHEQEKIREEEKRQEQEEMWRQEE 530 Query: 2452 LAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD--QRQVPLGGRRGRKD 2509 K + E + + I ++ + + EE H+ ++ + Q R+ K Sbjct: 531 ---KIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKI 587 Query: 2510 RERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEK 2561 RE+E +E+ EK R E+E+ +E+ EK+ EE+ + E ++ E K + Sbjct: 588 REQEEKIREQEEKIR-EQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRR 638 Score = 64.3 bits (155), Expect = 3e-09 Identities = 61/283 (21%), Positives = 133/283 (46%), Gaps = 24/283 (8%) Query: 2283 EERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQE 2342 EE K K A +EK +L ++ E +E K +R +++ + E + L KE+Q Sbjct: 278 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 337 Query: 2343 KKLQQELERQKEEDELKRRVKKGKQGPI--KEEPPMKKSQAANKQVPPLTKVDVKMETIE 2400 + +L+ Q EE+EL R+ + ++ + +EE + + +Q + + + K+ E Sbjct: 338 --VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 395 Query: 2401 RKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYE 2460 K+ +E+ M EKEE K R ++ ++ QE+ + + K + E Sbjct: 396 EKMRRQEEMMWEKEE---KMRRQEEMMWEKEEKMRRQEEMMWEKEE--------KIRELE 444 Query: 2461 LTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERT 2520 + + + I +++Q EE ++RQ ++++ RE+ EK R Sbjct: 445 EKMHEQEKIREQEEKRQ---------EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 495 Query: 2521 EKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDL 2563 ++E++ R++ + EK+R E+R + E ++ + ++++++ Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 538 Score = 61.6 bits (148), Expect = 2e-08 Identities = 63/317 (19%), Positives = 148/317 (46%), Gaps = 22/317 (6%) Query: 2263 LNMAQDYAAMKAQEKAKK------EQEE--RKHKGALEKEKERLQNMDE---EEYDALTE 2311 LN Q+ + +EK ++ EQEE R+ + + +++E+++ +E E+ + + Sbjct: 355 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 414 Query: 2312 EEKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQE-LERQKEEDELKRRVKKGKQGPI 2370 +E++ +++ + +E E+E +E++EK +QE + Q+E+ + + ++++ ++ Sbjct: 415 QEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 474 Query: 2371 KEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHG 2430 +E ++ + +Q + + + KM E KI +E+ E++ +++ + + Sbjct: 475 QEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIRE 534 Query: 2431 LPLVQDQE----DSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGM 2486 + Q+ + E K +K + K ++ K + W +++ ++ + Sbjct: 535 QEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKI 594 Query: 2487 EE-----APHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRAL 2541 E E Q Q G + K E+E +E+ EK R + EK RE+ +K+R Sbjct: 595 REQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKI-REQEKKIREQ 653 Query: 2542 EERSDWEGEGEEDHEGK 2558 EE+ + E ++ E K Sbjct: 654 EEKIREQEEMMQEQEEK 670 Score = 55.8 bits (133), Expect = 1e-06 Identities = 39/151 (25%), Positives = 86/151 (56%), Gaps = 9/151 (5%) Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKK- 2330 ++ QE+ QEE+ H EK +E+ + + +E +EEK+ R ++ +RE+++ Sbjct: 552 IRKQEEKMWRQEEKMHDQE-EKIREQEEKVWRQEEKIREQEEKI---REQEEKIREQEEM 607 Query: 2331 -REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPL 2389 +EQE E +EK +QE + Q++E++++R+ +K ++ +E+ ++ + +Q + Sbjct: 608 TQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIRE---QEKKIREQEEKIREQEEMM 664 Query: 2390 TKVDVKMETIERKISVREQTMSEKEELNKKK 2420 + + KM E K+ +E+ M E+EE +++ Sbjct: 665 QEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQ 695 Score = 52.0 bits (123), Expect = 2e-05 Identities = 45/186 (24%), Positives = 93/186 (50%), Gaps = 23/186 (12%) Query: 2254 IGSREHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEE 2313 I +E I Q+ M QE+ +EQEE + ++KE++ E+E +EE Sbjct: 507 IHEQEKIREEEKRQEQEEMWRQEEKIREQEE------IWRQKEKIH---EQEEKIRKQEE 557 Query: 2314 KLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEE 2373 K+ +E K +QE +E +EK +QE + +++E++++ + +K ++ +EE Sbjct: 558 KMW--------RQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIRE---QEE 606 Query: 2374 PPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPL 2433 ++ + +Q + + + KM+ E K+ +E+ + E+E KK R + + Sbjct: 607 MTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQE---KKIREQEEKIREQEEM 663 Query: 2434 VQDQED 2439 +Q+QE+ Sbjct: 664 MQEQEE 669 Score = 51.2 bits (121), Expect = 3e-05 Identities = 36/141 (25%), Positives = 77/141 (54%), Gaps = 5/141 (3%) Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQE 2334 QE+ +EQEE K + EK +E+ + E+E +EEK+ Q E+ +R++E Sbjct: 583 QEEKIREQEE-KIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEE 641 Query: 2335 RLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDV 2394 ++ + QEKK++++ E+ +E++E+ + ++ +EE ++ + +Q + + + Sbjct: 642 KIRE--QEKKIREQEEKIREQEEMMQEQEEKMWE--QEEKMCEQEEKMQEQEEKMRRQEE 697 Query: 2395 KMETIERKISVREQTMSEKEE 2415 KM E ++ +E+ M E +E Sbjct: 698 KMWEQEVRLRQQEEKMQEHQE 718 Score = 50.1 bits (118), Expect = 6e-05 Identities = 35/164 (21%), Positives = 90/164 (54%), Gaps = 14/164 (8%) Query: 2267 QDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALR 2326 Q+ + +EK +++E+ + +++E+++ +E+ + E+E++T ++ + + Sbjct: 569 QEEKIREQEEKVWRQEEK------IREQEEKIREQEEK----IREQEEMTQEQEEKMGEQ 618 Query: 2327 ERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQV 2386 E K EQE +E +EK +QE + +++E +++ + +K ++ +EE ++ + +Q Sbjct: 619 EEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIRE---QEEMMQEQEEKMWEQE 675 Query: 2387 PPLTKVDVKMETIERKISVREQTMSEKE-ELNKKKRNMGDVSMH 2429 + + + KM+ E K+ +E+ M E+E L +++ M + H Sbjct: 676 EKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEH 719 Score = 45.1 bits (105), Expect = 0.002 Identities = 23/100 (23%), Positives = 59/100 (59%), Gaps = 5/100 (5%) Query: 2265 MAQDYAAMKAQEKAKKEQEE--RKHKGALEKEKERLQNMDE---EEYDALTEEEKLTFDR 2319 M + M QE+ +EQEE R+ + + +++++++ +E E+ + + E+E+ +++ Sbjct: 615 MGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 674 Query: 2320 GIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELK 2359 + +E K +EQE + +EK +QE+ +++E++++ Sbjct: 675 EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 714 Score = 43.9 bits (102), Expect = 0.004 Identities = 28/93 (30%), Positives = 52/93 (55%), Gaps = 3/93 (3%) Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324 M + M+ QE+ +EQE +K + EK +E+ + M E+E +EEK+ Q Sbjct: 629 MQEQEEKMRRQEEKIREQE-KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 687 Query: 2325 LRERKKREQERLAKEMQEKKLQQELERQKEEDE 2357 E+ +R++E++ + QE +L+Q+ E+ +E E Sbjct: 688 QEEKMRRQEEKMWE--QEVRLRQQEEKMQEHQE 718 Score = 41.2 bits (95), Expect = 0.027 Identities = 28/118 (23%), Positives = 59/118 (50%), Gaps = 1/118 (0%) Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324 M Q+ +++ K ++E K + EK + + + + E+E +EEK+ + Q Sbjct: 607 MTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQE 666 Query: 2325 LRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAA 2382 +E K EQE E +EK +QE + +++E+++ + + +Q K + + +AA Sbjct: 667 -QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAA 723 >gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo sapiens] Length = 600 Score = 70.1 bits (170), Expect = 5e-11 Identities = 67/297 (22%), Positives = 135/297 (45%), Gaps = 33/297 (11%) Query: 2271 AMKAQEKAKKEQEERKHKGALEKEKERLQNMDEE-EYDALTEEEKLTFDRGIQQALRERK 2329 A K +E+ + +R+ + +KE+ER +N E E + E+E T DR ++ + Sbjct: 155 AEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERG----R 210 Query: 2330 KREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPL 2389 +RE+ER + E+K Q + ER ++ + R K+ ++ E + + ++ Sbjct: 211 ERERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDR 270 Query: 2390 TKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPD 2449 + D + + ER+ + Q +E++ ++KR + Q + E + ++ Sbjct: 271 DR-DRRQKERERQTDRKRQRRTERDRETERKR-------------ERQRERERERERNRK 316 Query: 2450 KQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKD 2509 ++ + + ++ + DR++ + E E + Q GR GR+ Sbjct: 317 RERERERERERERQRETER-----DREKERERKRKRQTEMDRERNRQT-----GREGRRQ 366 Query: 2510 RERER-LEKERTEKERLEREKAERER---LEKLRALEERSDWEGEGEEDHEGKKEKD 2562 ERER E+ER + ERE+ ER+R +K R + D +G+ E + + ++EKD Sbjct: 367 AERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKD 423 Score = 67.4 bits (163), Expect = 3e-10 Identities = 72/292 (24%), Positives = 130/292 (44%), Gaps = 50/292 (17%) Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQE 2334 +EK ++ Q +R+ EKE+ R + + E TE E +RG + +++RE++ Sbjct: 101 REKERERQTDRERDRQREKERNRQKERERE-----TEREG---ERGRDRQTDGQRERERQ 152 Query: 2335 RLAKEMQEKKLQQELERQKEEDELKRRVK-KGKQGPIKEEPPMKKSQAANKQVPPLTKVD 2393 R A++ +E++ +E +RQ E + K R + K +Q + E +K + + Sbjct: 153 RDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRER 212 Query: 2394 VKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQE-DSEGDNSKDPDKQL 2452 + E + + QT E++ K +R + ++ E D E + +D D+ Sbjct: 213 ERERETETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDR 272 Query: 2453 APKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRER 2512 DR+Q +E + D +RQ RR +DRE Sbjct: 273 ---------------------DRRQ---------KERERQTDRKRQ-----RRTERDRET 297 Query: 2513 ERLEKERTEKERLERE---KAERERLEKLRALEERSDWEGEGEEDHEGKKEK 2561 ER + + E+ER ERE K ERER E+ R E + + E + E++ E K+++ Sbjct: 298 ERKRERQRERER-ERERNRKRERER-ERERERERQRETERDREKERERKRKR 347 Score = 64.3 bits (155), Expect = 3e-09 Identities = 66/303 (21%), Positives = 137/303 (45%), Gaps = 27/303 (8%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRER-KKR 2331 +A + A + ER + E+ +E+ Q E + EK + + R+R +++ Sbjct: 44 QAHKDADGDDRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREK 103 Query: 2332 EQERLAKEMQEKKLQQELERQKE-EDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLT 2390 E+ER ++++ ++E RQKE E E +R ++G+ + ++ + A K+ T Sbjct: 104 ERERQTDRERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQT 163 Query: 2391 KVDVKMETIERKISVREQTMSEKE----ELNKKKRNMGD--VSMHGLPLVQDQE-DSEGD 2443 + + +T + RE+ + +E E ++K N + S G +++E ++E + Sbjct: 164 DRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETE 223 Query: 2444 NSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGG 2503 + D++ + KT +R++ + A E + + +R+ Sbjct: 224 RKRQTDRERDRQRKTER-------------EREKQAERERASERETERDKERERERDRDR 270 Query: 2504 RRGRKDRERE----RLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKK 2559 R R+ +ERE R + RTE++R K ER+R E+ R E E E E + E ++ Sbjct: 271 DRDRRQKERERQTDRKRQRRTERDRETERKRERQR-ERERERERNRKRERERERERERER 329 Query: 2560 EKD 2562 +++ Sbjct: 330 QRE 332 Score = 47.4 bits (111), Expect = 4e-04 Identities = 63/298 (21%), Positives = 126/298 (42%), Gaps = 28/298 (9%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDAL----TEEEKLTFDRGIQQALRER 2328 +A E+ + +ER+ + +++++R Q E + D TE ++ T + +Q RER Sbjct: 250 RASERETERDKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERER 309 Query: 2329 KKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPP 2388 + RE+ R + +E++ ++E +R+ E D K R +K K+ + E ++++ ++ Sbjct: 310 E-RERNRKRERERERERERERQRETERDREKERERKRKR---QTEMDRERNRQTGREGRR 365 Query: 2389 LTKVDVKMETIERKISVREQTMSEKE---ELNKKKRNMGDVSMHGLPLVQDQEDSEGDNS 2445 + + + E + S RE+ E++ + K++ + G + Q + E D Sbjct: 366 QAERERERERERDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRE 425 Query: 2446 KDPDKQLAPKFKTYELTLKDVQNILMYWDRKQG---------VQLPPAGMEEAPHEPDDQ 2496 + ++ + + + +D + DR+ G V PP + D Sbjct: 426 SERGRERGREREKQKGRERDRER---QTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPN 482 Query: 2497 RQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEER-SDWEGEGEE 2553 R P G R + E + R R KA R R+ R E R + G+G E Sbjct: 483 R--PTRGIRWKSSPEDPKAASTRFPWGR--PAKASRGRVAGRRRWEPRLGEKRGQGGE 536 Score = 42.7 bits (99), Expect = 0.009 Identities = 30/119 (25%), Positives = 64/119 (53%), Gaps = 12/119 (10%) Query: 2264 NMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQ 2323 N ++ + +E+ ++ + ER + E++++R MD E + T G +Q Sbjct: 314 NRKRERERERERERERQRETERDREKERERKRKRQTEMDR-------ERNRQTGREGRRQ 366 Query: 2324 ALRER-KKREQER-LAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQ 2380 A RER ++RE++R A+E +E++ ++ +RQKE + R+ +K + G + E ++ + Sbjct: 367 AERERERERERDRQSAREREERERDRDRDRQKERE---RQTEKDRDGQRETEKQREREK 422 Score = 39.3 bits (90), Expect = 0.10 Identities = 36/184 (19%), Positives = 80/184 (43%), Gaps = 14/184 (7%) Query: 2268 DYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRE 2327 D + E+ ++ + +R+ + E+E+ER + + E E + +R ++ RE Sbjct: 284 DRKRQRRTERDRETERKRERQRERERERERNRKRERERERERERERQRETERD-REKERE 342 Query: 2328 RKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387 RK++ Q + +E + ++ +E RQ E + + R + + +EE + + K+ Sbjct: 343 RKRKRQTEMDRE-RNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERE 401 Query: 2388 PLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKD 2447 T+ D + + +Q EK+ +++ R G + Q+ E D + Sbjct: 402 RQTEKD-----RDGQRETEKQREREKDRESERGRERGRER-------EKQKGRERDRERQ 449 Query: 2448 PDKQ 2451 D+Q Sbjct: 450 TDRQ 453 >gi|4503509 eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa [Homo sapiens] Length = 1382 Score = 69.7 bits (169), Expect = 7e-11 Identities = 76/313 (24%), Positives = 137/313 (43%), Gaps = 39/313 (12%) Query: 2258 EHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEK--ERLQNMDEEEYDALTEEEKL 2315 E I ++ A + +K + ++++EER LE+EK E M D +L Sbjct: 705 EEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRL 764 Query: 2316 TFDRGIQQALRERKKREQERLAKE----MQEKKLQQELER------QKEEDELKRRVKKG 2365 R Q E+ K+ +ERLA+E ++E+K Q++ ER +KEE+E +R Sbjct: 765 KAAR--QSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRR----A 818 Query: 2366 KQGPIKEEPPMKKSQAANKQ--VPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNM 2423 ++ +KE ++++ A ++ + + K+E +ERK RE + E+E +++R + Sbjct: 819 EEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERRL 878 Query: 2424 GDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPP 2483 GD S+ DSEG K P+ + E W R +G Sbjct: 879 GDSSLSRKDSRWGDRDSEGTWRKGPEADSEWRRGPPE----------KEWRRGEGRD--- 925 Query: 2484 AGMEEAPHEPDDQRQVPLGGRRGRKDRER---ERLEKERTEKERLEREKAERERLEKLRA 2540 E+ H D++R LG R+ R +R+ + + +R R E +R + A Sbjct: 926 ---EDRSHRRDEERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGPRRGPEEDRFSRRGA 982 Query: 2541 LEERSDWEGEGEE 2553 ++R W ++ Sbjct: 983 DDDRPSWRNTDDD 995 Score = 63.5 bits (153), Expect = 5e-09 Identities = 73/321 (22%), Positives = 148/321 (46%), Gaps = 28/321 (8%) Query: 2261 YILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRG 2320 Y+ N +++ + A+ + +E++ER +++EKE L+ + E EE Sbjct: 557 YLKNSRKEHQRILARRQTIEERKERLESLNIQREKEELEQREAELQKVRKAEE------- 609 Query: 2321 IQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQ 2380 ++ +E K+RE+ER+ +E ++ K + ER ++ + + K K I++ + Sbjct: 610 -ERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDF 668 Query: 2381 AANKQVPPLTK----VDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQD 2436 KQV L K + +++ E+KI E+ EE+ K + + + L + Sbjct: 669 IMAKQVEQLEKEKKELQERLKNQEKKIDYFERA-KRLEEIPLIKSAYEEQRIKDMDLWEQ 727 Query: 2437 QEDS-------EGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEA 2489 QE+ E + + + +++ + +L + ++ ++ Q EE Sbjct: 728 QEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEER 787 Query: 2490 PHEPDDQRQVPLGGRRGRKDRERERLEKERTE----KERLEREKAER-ERLEKLRALEER 2544 + +++++ RR RE+E E+ R E KER ERE+AER +R E+LR +ER Sbjct: 788 HNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQER 847 Query: 2545 SDWEGEGEEDHEGKKEKDLGV 2565 + EE K++++L + Sbjct: 848 VK---KLEEVERKKRQRELEI 865 Score = 59.7 bits (143), Expect = 7e-08 Identities = 79/355 (22%), Positives = 161/355 (45%), Gaps = 51/355 (14%) Query: 2257 REHIYILNMAQDYAAMKAQE----KAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEE 2312 +E + LN+ ++ ++ +E K +K +EER + A E+EKER+ + E+ T Sbjct: 579 KERLESLNIQREKEELEQREAELQKVRKAEEERLRQEAKEREKERILQ-EHEQIKKKTVR 637 Query: 2313 EKLTFDRGIQ---QALRERKKREQERLAKEMQEKKLQQELERQKEE--DELKRRVKK--- 2364 E+L + + +A ++ + E L + K ++LE++K+E + LK + KK Sbjct: 638 ERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQEKKIDY 697 Query: 2365 GKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMG 2424 ++ EE P+ KS +++ + + + E ER +++ + E N+ R + Sbjct: 698 FERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEE--ERITTMQLEREKALEHKNRMSRMLE 755 Query: 2425 DVSMHGLPLVQDQEDSEGDNSKDPDKQLAP----KFKTYELTLKDVQNILMYWDRKQGVQ 2480 D + + L ++ + K +++LA + + + K+ + I Y ++++ Q Sbjct: 756 DRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQ 815 Query: 2481 LPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAE-RERLEKLR 2539 RR + +ER E+ER E+ + E E E +ER++KL Sbjct: 816 -----------------------RRAEEQMLKEREERERAERAKREEELREYQERVKKLE 852 Query: 2540 ALEERSDWEGEGEEDHEGKKEKD--LGVPFLDIQTP-----DFEGLSWKQALESD 2587 +E + E+ E ++E++ LG L + D EG +W++ E+D Sbjct: 853 EVERKKRQRELEIEERERRREEERRLGDSSLSRKDSRWGDRDSEG-TWRKGPEAD 906 Score = 38.5 bits (88), Expect = 0.17 Identities = 58/269 (21%), Positives = 106/269 (39%), Gaps = 71/269 (26%) Query: 2286 KHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQEKKL 2345 K G EKEK R ++ +EE + +DR K+R+++ +E +K Sbjct: 1174 KPGGWREKEKAREESWGPPRESRPSEERE--WDR--------EKERDRDNQDREENDKDP 1223 Query: 2346 QQELERQKE---EDELKRRVKKG--KQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIE 2400 ++E +R+++ ED +R +G ++GP +E + S + + Sbjct: 1224 ERERDRERDVDREDRFRRPRDEGGWRRGPAEESSSWRDSSRRD----------------D 1267 Query: 2401 RKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYE 2460 R R + ++ +L +++ D G PL ++E+ D Sbjct: 1268 RDRDDRRRERDDRRDLRERRDLRDDRDRRGPPLRSEREEVSSWRRAD------------- 1314 Query: 2461 LTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERT 2520 DRK ++ E D R+VP +DRER+R + Sbjct: 1315 -------------DRK----------DDRVEERDPPRRVPPPAL--SRDRERDRDREREG 1349 Query: 2521 EKERLEREKAERERLEKLRALEERSDWEG 2549 EKE+ +AE++R E LR + +D +G Sbjct: 1350 EKEKAS-WRAEKDR-ESLRRTKNETDEDG 1376 Score = 33.5 bits (75), Expect = 5.6 Identities = 48/221 (21%), Positives = 80/221 (36%), Gaps = 50/221 (22%) Query: 2349 LERQKEEDELKRRVKKGKQGP----IKEEPPMKKSQAANKQVPPLTKVDVKMETIERKIS 2404 L R+ ++D RR + GP +K +K +A + P Sbjct: 1148 LSRRADDDRFPRRGDDSRPGPWRPLVKPGGWREKEKAREESWGP---------------- 1191 Query: 2405 VREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLK 2464 RE SE+ E +++K D QD+E+++ D ++ D++ + Sbjct: 1192 PRESRPSEEREWDREKERDRDN--------QDREENDKDPERERDRE------------R 1231 Query: 2465 DVQNILMYWDRKQGVQLP--PAGMEEAPHEPDDQ-RQVPLGGRRGRKDRERERLEKERTE 2521 DV DR+ + P G P E R R R DR RER ++ Sbjct: 1232 DV-------DREDRFRRPRDEGGWRRGPAEESSSWRDSSRRDDRDRDDRRRERDDRRDLR 1284 Query: 2522 KERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKD 2562 + R R+ +R EE S W + + +E+D Sbjct: 1285 ERRDLRDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERD 1325 Score = 33.1 bits (74), Expect = 7.3 Identities = 31/107 (28%), Positives = 49/107 (45%), Gaps = 19/107 (17%) Query: 2495 DQRQVPLGGRRGRKDRERERLEKERTEKERLERE------KAERERLEKLRALEERSDWE 2548 +QR+ L R + + ER R E + EKER+ +E K RERLE+++ E + Sbjct: 595 EQREAELQKVR-KAEEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGA--- 650 Query: 2549 GEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQALESDKLPKGEQI 2595 K KD+ + L+ PDF + LE +K E++ Sbjct: 651 ---------KAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERL 688 >gi|102467235 inner centromere protein antigens 135/155kDa isoform 1 [Homo sapiens] Length = 918 Score = 65.9 bits (159), Expect = 1e-09 Identities = 57/217 (26%), Positives = 109/217 (50%), Gaps = 21/217 (9%) Query: 2276 EKAKKEQ--EERKHKGALEKEKERLQNMDEEEYDA-----LTEEEKLTFDRGIQQALRER 2328 EKAK+E+ EE+ K A K+ E ++ ++E +A L +EE+ +R Q+ L+++ Sbjct: 611 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE---ERRHQELLQKK 667 Query: 2329 KKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPP 2388 K+ EQERL K + K+L ++ E+++ E E + + ++ ++ +E ++ A ++ Sbjct: 668 KEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRRE 727 Query: 2389 LTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDP 2448 ++ + E ER+ ++R Q + EL +KK+ + L ++QE Sbjct: 728 QERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA------- 780 Query: 2449 DKQLAPKFKTYELTLKDVQN--ILMYWDRKQGVQLPP 2483 K+ A K +T+ DVQ+ Y QG + PP Sbjct: 781 -KEAAGASKALNVTV-DVQSPACTSYQMTPQGHRAPP 815 Score = 64.3 bits (155), Expect = 3e-09 Identities = 65/298 (21%), Positives = 135/298 (45%), Gaps = 48/298 (16%) Query: 2291 LEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELE 2350 +EKE++RL+N+ +E +K+ D+ ++ L E K + +ERL K +Q ++ ++++ Sbjct: 535 VEKERQRLENLRRKEEAEQLRRQKVEEDK--RRRLEEVKLKREERLRKVLQARERVEQMK 592 Query: 2351 RQKEED------ELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKIS 2404 +K++ ++ + +K K+ + EE KK+ A + + + R + Sbjct: 593 EEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQ 652 Query: 2405 VREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLK 2464 E+ +E L KKK +E+ E K+LA + + Sbjct: 653 QEEEERRHQELLQKKK----------------EEEQERLRKAAEAKRLAEQREQ------ 690 Query: 2465 DVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQV-PLGGRRGRKDRERERLEKERTEKE 2523 +R++ + E+ E + + Q L + R+++ER + E+E E+E Sbjct: 691 ---------ERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQERE 741 Query: 2524 ---RLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVP-----FLDIQTP 2573 RL++E+ +RE EK + E++ E + +E+ E K ++ G +D+Q+P Sbjct: 742 KALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSP 799 Score = 55.1 bits (131), Expect = 2e-06 Identities = 44/172 (25%), Positives = 87/172 (50%), Gaps = 25/172 (14%) Query: 2265 MAQDYAAMKAQEKAKK------EQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFD 2318 M + A K +E+A++ E+EER+H+ L+K+KE E+E+L Sbjct: 632 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE-------------EQERL--- 675 Query: 2319 RGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKK 2378 R +A R ++REQER +E +E++ +++ R++E E +R++ + ++ +E ++ Sbjct: 676 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAER 735 Query: 2379 SQAANKQVPPLTKVDVKMETIERKISVREQTMSEK---EELNKKKRNMGDVS 2427 ++ L K ++ E E+K +Q ++E+ EE KK + S Sbjct: 736 ELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGAS 787 Score = 46.2 bits (108), Expect = 8e-04 Identities = 37/126 (29%), Positives = 67/126 (53%), Gaps = 10/126 (7%) Query: 2271 AMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKK 2330 A + E+ ++E+ E++ + +E+ER + E+ L E+E+ +Q A RE ++ Sbjct: 681 AKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQ-AERELQE 739 Query: 2331 REQE-RLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPL 2389 RE+ RL KE LQ+ELE +K+++E +R ++ ++EE K +AA Sbjct: 740 REKALRLQKEQ----LQRELEEKKKKEEQQRLAER----QLQEEQEKKAKEAAGASKALN 791 Query: 2390 TKVDVK 2395 VDV+ Sbjct: 792 VTVDVQ 797 >gi|102467242 inner centromere protein antigens 135/155kDa isoform 2 [Homo sapiens] Length = 914 Score = 65.9 bits (159), Expect = 1e-09 Identities = 57/217 (26%), Positives = 109/217 (50%), Gaps = 21/217 (9%) Query: 2276 EKAKKEQ--EERKHKGALEKEKERLQNMDEEEYDA-----LTEEEKLTFDRGIQQALRER 2328 EKAK+E+ EE+ K A K+ E ++ ++E +A L +EE+ +R Q+ L+++ Sbjct: 607 EKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEE---ERRHQELLQKK 663 Query: 2329 KKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPP 2388 K+ EQERL K + K+L ++ E+++ E E + + ++ ++ +E ++ A ++ Sbjct: 664 KEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRRE 723 Query: 2389 LTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDP 2448 ++ + E ER+ ++R Q + EL +KK+ + L ++QE Sbjct: 724 QERLQAERELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKA------- 776 Query: 2449 DKQLAPKFKTYELTLKDVQN--ILMYWDRKQGVQLPP 2483 K+ A K +T+ DVQ+ Y QG + PP Sbjct: 777 -KEAAGASKALNVTV-DVQSPACTSYQMTPQGHRAPP 811 Score = 63.9 bits (154), Expect = 4e-09 Identities = 65/297 (21%), Positives = 134/297 (45%), Gaps = 48/297 (16%) Query: 2292 EKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELER 2351 EKE++RL+N+ +E +K+ D+ ++ L E K + +ERL K +Q ++ ++++ Sbjct: 532 EKERQRLENLRRKEEAEQLRRQKVEEDK--RRRLEEVKLKREERLRKVLQARERVEQMKE 589 Query: 2352 QKEED------ELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISV 2405 +K++ ++ + +K K+ + EE KK+ A + + + R + Sbjct: 590 EKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQ 649 Query: 2406 REQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKD 2465 E+ +E L KKK +E+ E K+LA + + Sbjct: 650 EEEERRHQELLQKKK----------------EEEQERLRKAAEAKRLAEQREQ------- 686 Query: 2466 VQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQV-PLGGRRGRKDRERERLEKERTEKE- 2523 +R++ + E+ E + + Q L + R+++ER + E+E E+E Sbjct: 687 --------ERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREK 738 Query: 2524 --RLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVP-----FLDIQTP 2573 RL++E+ +RE EK + E++ E + +E+ E K ++ G +D+Q+P Sbjct: 739 ALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQSP 795 Score = 60.5 bits (145), Expect = 4e-08 Identities = 56/218 (25%), Positives = 110/218 (50%), Gaps = 32/218 (14%) Query: 2329 KKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPP 2388 K++E++RL + ++ K+ ++L RQK E++ +RR+++ K +K E ++K A ++V Sbjct: 531 KEKERQRL-ENLRRKEEAEQLRRQKVEEDKRRRLEEVK---LKREERLRKVLQARERVEQ 586 Query: 2389 LTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDP 2448 + + K + IE+K + + EK E K++R L ++ K Sbjct: 587 MK--EEKKKQIEQKFA----QIDEKTEKAKEER-----------LAEE---------KAK 620 Query: 2449 DKQLAPKFKTYELTLKDVQNI--LMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRG 2506 K A K + E K + L + +++ + +++ E ++ + +R Sbjct: 621 KKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRL 680 Query: 2507 RKDRERERLEKERTEKERLEREKAERERLEKLRALEER 2544 + RE+ER E+ER E+ER E+E+ E+ER E+ R L E+ Sbjct: 681 AEQREQERREQERREQERREQERREQERREQERQLAEQ 718 Score = 55.1 bits (131), Expect = 2e-06 Identities = 44/172 (25%), Positives = 87/172 (50%), Gaps = 25/172 (14%) Query: 2265 MAQDYAAMKAQEKAKK------EQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFD 2318 M + A K +E+A++ E+EER+H+ L+K+KE E+E+L Sbjct: 628 MEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEE-------------EQERL--- 671 Query: 2319 RGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKK 2378 R +A R ++REQER +E +E++ +++ R++E E +R++ + ++ +E ++ Sbjct: 672 RKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAER 731 Query: 2379 SQAANKQVPPLTKVDVKMETIERKISVREQTMSEK---EELNKKKRNMGDVS 2427 ++ L K ++ E E+K +Q ++E+ EE KK + S Sbjct: 732 ELQEREKALRLQKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGAS 783 Score = 46.2 bits (108), Expect = 8e-04 Identities = 37/126 (29%), Positives = 67/126 (53%), Gaps = 10/126 (7%) Query: 2271 AMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKK 2330 A + E+ ++E+ E++ + +E+ER + E+ L E+E+ +Q A RE ++ Sbjct: 677 AKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQ-AERELQE 735 Query: 2331 REQE-RLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPL 2389 RE+ RL KE LQ+ELE +K+++E +R ++ ++EE K +AA Sbjct: 736 REKALRLQKEQ----LQRELEEKKKKEEQQRLAER----QLQEEQEKKAKEAAGASKALN 787 Query: 2390 TKVDVK 2395 VDV+ Sbjct: 788 VTVDVQ 793 Score = 32.7 bits (73), Expect = 9.5 Identities = 27/113 (23%), Positives = 49/113 (43%), Gaps = 7/113 (6%) Query: 2436 DQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD 2495 D+E D P + P + ++ ++ + + P + + Sbjct: 461 DEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFI 520 Query: 2496 QRQVPLGGRRGRKDRERERLE--KERTEKERLEREKAE---RERLEKLRALEE 2543 +R PL R K++ER+RLE + + E E+L R+K E R RLE+++ E Sbjct: 521 KRNTPL--RMDPKEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE 571 >gi|15149465 caldesmon 1 isoform 5 [Homo sapiens] Length = 532 Score = 65.5 bits (158), Expect = 1e-09 Identities = 80/336 (23%), Positives = 146/336 (43%), Gaps = 31/336 (9%) Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQE 2334 QE+ +++QEE ++ + QN +E +A T + + A ER R +E Sbjct: 41 QERLRQKQEEESLGQVTDQVEVNAQNSVPDE-EAKTTTTNTQVEGDDEAAFLERLARREE 99 Query: 2335 RLAKEMQEKKLQQELERQKEED------ELKRRVKKGKQGPIKEEPPMKKSQAANKQ--- 2385 R ++K+LQ+ LERQKE D L ++ + + E K+ ++ ++Q Sbjct: 100 R-----RQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERY 154 Query: 2386 ----VPPLTKVDVKMETIERKISVREQTMSEKEELNKKKR-NMGDVSMHGLPLVQDQEDS 2440 +TK K + + + + +E E+EE K KR ++G+ + + +D+E Sbjct: 155 EIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPK 214 Query: 2441 EGDNS-KDPDKQLAP------KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEP 2493 E S D K +F T++L K +N + V A E AP Sbjct: 215 EEVKSFMDRKKGFTEVKSQNGEFMTHKL--KHTENTFSRPGGRASVDTKEA--EGAPQVE 270 Query: 2494 DDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEE 2553 +R L RRG + E K++ ++ LE E+ +++R E+ + LEE + E Sbjct: 271 AGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEA 330 Query: 2554 DHEGKKEKDLGVPFLDIQTPDFEGLSWKQALESDKL 2589 D + ++E++ +I+ E +Q + D L Sbjct: 331 DRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGL 366 Score = 56.2 bits (134), Expect = 8e-07 Identities = 74/305 (24%), Positives = 132/305 (43%), Gaps = 40/305 (13%) Query: 2268 DYAAMKAQEKAKKEQEERKHKGALEKEKE---------------RLQNMDEEEYDALTEE 2312 D AA + ++E+ +++ + ALE++KE R+QN D E + +E Sbjct: 86 DEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQN-DTAENETTEKE 144 Query: 2313 EKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELK--RRVKKGKQGPI 2370 EK ++ +ER + E+ + +K ++ E K+ED+ K +K K+G I Sbjct: 145 EK-------SESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 197 Query: 2371 KEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHG 2430 E K + K P K +VK +K ++ + + +K K S G Sbjct: 198 GEN--QIKDEKIKKDKEP--KEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPG 253 Query: 2431 LPLVQDQEDSEGDNSKDPDKQLAP-KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEA 2489 D +++EG + K+L + + E ++ + + KQ Q +EE Sbjct: 254 GRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKL------KQKQQEAALELEEL 307 Query: 2490 PHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEG 2549 + +++R+V + RK E +R +E EK RL +E+ ER R E A E+R Sbjct: 308 KKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRL-KEEIERRRAE---AAEKRQKMPE 363 Query: 2550 EGEED 2554 +G D Sbjct: 364 DGLSD 368 Score = 49.3 bits (116), Expect = 1e-04 Identities = 51/215 (23%), Positives = 93/215 (43%), Gaps = 24/215 (11%) Query: 2276 EKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRG-----IQQALRERKK 2330 E K+ +E R+ +G E E E + + +++ +A E E+L R +++ + RK+ Sbjct: 270 EAGKRLEELRRRRG--ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQ 327 Query: 2331 REQERLAKEMQEK-KLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPL 2389 E +R +E +EK +L++E+ER++ E KR+ K + G ++ P K + Sbjct: 328 EEADRKLREEEEKRRLKEEIERRRAEAAEKRQ-KMPEDGLSDDKKPFKCFTPKGSSL--- 383 Query: 2390 TKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPD 2449 K++ + E + + + +K K VS L Q EG S P Sbjct: 384 -KIEERAEFLNKSV--------QKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPT 434 Query: 2450 KQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPA 2484 K P + + V+NI W++ P A Sbjct: 435 K---PAASDLPVPAEGVRNIKSMWEKGNVFSSPTA 466 Score = 44.7 bits (104), Expect = 0.002 Identities = 63/301 (20%), Positives = 134/301 (44%), Gaps = 37/301 (12%) Query: 2321 IQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKR---RVKKGKQGPIKEEPPMK 2377 + Q +R ++E A+E + + Q+ L +++EE+ L + +V+ Q + +E Sbjct: 16 LSQIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVEVNAQNSVPDEE--A 73 Query: 2378 KSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKK-KRNMGDVSMHGLPLVQD 2436 K+ N QV + +E + R+ R++ + E E K+ + D S+ LP + Sbjct: 74 KTTTTNTQVEGDDEA-AFLERLARREERRQKRLQEALERQKEFDPTITDASL-SLPSRRM 131 Query: 2437 QEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQ 2496 Q D+ + + + +++ + + YE +++ + + + +K + +E + +++ Sbjct: 132 QNDTAENETTEKEEKSESRQERYE--IEETETVTKSY-QKNDWRDAEENKKEDKEKEEEE 188 Query: 2497 RQVPLGGRRGRKDRERERLEKERTEKER----LEREKAERE--------RLEKLRALEER 2544 + P G G + E+++K++ KE ++R+K E KL+ E Sbjct: 189 EEKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENT 248 Query: 2545 ----------SDWEGEGEEDHE-GKKEKDLGVPFLDIQTPDFEGLSWKQ---ALESDKLP 2590 E EG E GK+ ++L + ++ +FE L KQ ALE ++L Sbjct: 249 FSRPGGRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELK 308 Query: 2591 K 2591 K Sbjct: 309 K 309 Score = 41.2 bits (95), Expect = 0.027 Identities = 52/224 (23%), Positives = 93/224 (41%), Gaps = 39/224 (17%) Query: 2261 YILNMAQDYAAMKAQEKAKKEQEERKHK------GALEKEKERLQNMDEEEYDALTEEEK 2314 Y N +D K ++K K+E+EE K K ++ EK + +EE + + +K Sbjct: 166 YQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKK 225 Query: 2315 ---------------------LTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQK 2353 TF R +A + K+ E A +++ K +EL R++ Sbjct: 226 GFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEG---APQVEAGKRLEELRRRR 282 Query: 2354 EEDELK--RRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMS 2411 E E + ++K+ +Q E +KK + ++V + K E +RK+ E+ Sbjct: 283 GETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRR 342 Query: 2412 EKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPK 2455 KEE+ +++ + +P ED D+ K P K PK Sbjct: 343 LKEEIERRRAEAAE-KRQKMP-----EDGLSDDKK-PFKCFTPK 379 >gi|4826657 caldesmon 1 isoform 2 [Homo sapiens] Length = 538 Score = 65.5 bits (158), Expect = 1e-09 Identities = 80/336 (23%), Positives = 146/336 (43%), Gaps = 31/336 (9%) Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQE 2334 QE+ +++QEE ++ + QN +E +A T + + A ER R +E Sbjct: 47 QERLRQKQEEESLGQVTDQVEVNAQNSVPDE-EAKTTTTNTQVEGDDEAAFLERLARREE 105 Query: 2335 RLAKEMQEKKLQQELERQKEED------ELKRRVKKGKQGPIKEEPPMKKSQAANKQ--- 2385 R ++K+LQ+ LERQKE D L ++ + + E K+ ++ ++Q Sbjct: 106 R-----RQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERY 160 Query: 2386 ----VPPLTKVDVKMETIERKISVREQTMSEKEELNKKKR-NMGDVSMHGLPLVQDQEDS 2440 +TK K + + + + +E E+EE K KR ++G+ + + +D+E Sbjct: 161 EIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPK 220 Query: 2441 EGDNS-KDPDKQLAP------KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEP 2493 E S D K +F T++L K +N + V A E AP Sbjct: 221 EEVKSFMDRKKGFTEVKSQNGEFMTHKL--KHTENTFSRPGGRASVDTKEA--EGAPQVE 276 Query: 2494 DDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEE 2553 +R L RRG + E K++ ++ LE E+ +++R E+ + LEE + E Sbjct: 277 AGKRLEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEA 336 Query: 2554 DHEGKKEKDLGVPFLDIQTPDFEGLSWKQALESDKL 2589 D + ++E++ +I+ E +Q + D L Sbjct: 337 DRKLREEEEKRRLKEEIERRRAEAAEKRQKMPEDGL 372 Score = 56.2 bits (134), Expect = 8e-07 Identities = 74/305 (24%), Positives = 132/305 (43%), Gaps = 40/305 (13%) Query: 2268 DYAAMKAQEKAKKEQEERKHKGALEKEKE---------------RLQNMDEEEYDALTEE 2312 D AA + ++E+ +++ + ALE++KE R+QN D E + +E Sbjct: 92 DEAAFLERLARREERRQKRLQEALERQKEFDPTITDASLSLPSRRMQN-DTAENETTEKE 150 Query: 2313 EKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELK--RRVKKGKQGPI 2370 EK ++ +ER + E+ + +K ++ E K+ED+ K +K K+G I Sbjct: 151 EK-------SESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSI 203 Query: 2371 KEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHG 2430 E K + K P K +VK +K ++ + + +K K S G Sbjct: 204 GEN--QIKDEKIKKDKEP--KEEVKSFMDRKKGFTEVKSQNGEFMTHKLKHTENTFSRPG 259 Query: 2431 LPLVQDQEDSEGDNSKDPDKQLAP-KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEA 2489 D +++EG + K+L + + E ++ + + KQ Q +EE Sbjct: 260 GRASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFEKL------KQKQQEAALELEEL 313 Query: 2490 PHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEG 2549 + +++R+V + RK E +R +E EK RL +E+ ER R E A E+R Sbjct: 314 KKKREERRKVLEEEEQRRKQEEADRKLREEEEKRRL-KEEIERRRAE---AAEKRQKMPE 369 Query: 2550 EGEED 2554 +G D Sbjct: 370 DGLSD 374 Score = 49.3 bits (116), Expect = 1e-04 Identities = 51/215 (23%), Positives = 93/215 (43%), Gaps = 24/215 (11%) Query: 2276 EKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRG-----IQQALRERKK 2330 E K+ +E R+ +G E E E + + +++ +A E E+L R +++ + RK+ Sbjct: 276 EAGKRLEELRRRRG--ETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQ 333 Query: 2331 REQERLAKEMQEK-KLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPL 2389 E +R +E +EK +L++E+ER++ E KR+ K + G ++ P K + Sbjct: 334 EEADRKLREEEEKRRLKEEIERRRAEAAEKRQ-KMPEDGLSDDKKPFKCFTPKGSSL--- 389 Query: 2390 TKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPD 2449 K++ + E + + + +K K VS L Q EG S P Sbjct: 390 -KIEERAEFLNKSV--------QKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPT 440 Query: 2450 KQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPA 2484 K P + + V+NI W++ P A Sbjct: 441 K---PAASDLPVPAEGVRNIKSMWEKGNVFSSPTA 472 Score = 41.2 bits (95), Expect = 0.027 Identities = 52/224 (23%), Positives = 93/224 (41%), Gaps = 39/224 (17%) Query: 2261 YILNMAQDYAAMKAQEKAKKEQEERKHK------GALEKEKERLQNMDEEEYDALTEEEK 2314 Y N +D K ++K K+E+EE K K ++ EK + +EE + + +K Sbjct: 172 YQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQIKDEKIKKDKEPKEEVKSFMDRKK 231 Query: 2315 ---------------------LTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQK 2353 TF R +A + K+ E A +++ K +EL R++ Sbjct: 232 GFTEVKSQNGEFMTHKLKHTENTFSRPGGRASVDTKEAEG---APQVEAGKRLEELRRRR 288 Query: 2354 EEDELK--RRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMS 2411 E E + ++K+ +Q E +KK + ++V + K E +RK+ E+ Sbjct: 289 GETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRR 348 Query: 2412 EKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPK 2455 KEE+ +++ + +P ED D+ K P K PK Sbjct: 349 LKEEIERRRAEAAE-KRQKMP-----EDGLSDDKK-PFKCFTPK 385 >gi|239754909 PREDICTED: hypothetical protein [Homo sapiens] Length = 245 Score = 65.1 bits (157), Expect = 2e-09 Identities = 37/148 (25%), Positives = 79/148 (53%), Gaps = 10/148 (6%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332 + +EK K++++E+K +G KE + + +E + + E E+ +R ++ +ERKKRE Sbjct: 108 EGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKERERKKEEREKERERKERKKRE 167 Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392 ++++ ++ +E+K ++ ER+K E K R K+ ++ +E +K + K Sbjct: 168 RKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKERKKKEERK-------- 219 Query: 2393 DVKMETIERKISVREQTMSEKEELNKKK 2420 K +R+ + RE+ ++E +KK Sbjct: 220 --KERQKDRQTNWREKERGKRERKERKK 245 Score = 64.3 bits (155), Expect = 3e-09 Identities = 70/251 (27%), Positives = 115/251 (45%), Gaps = 70/251 (27%) Query: 2320 GIQQALRERKK----REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPP 2375 G Q +RER++ R++ + +E + KK ++E E++K E E +R+ ++GK KE+ Sbjct: 33 GWQSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGK----KEK-- 86 Query: 2376 MKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQ 2435 K + K E ERK RE+ E EE K+K+ Sbjct: 87 ---------------KGERKKEERERKKRRREKENKEGEEKEKRKKK------------- 118 Query: 2436 DQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD 2495 ++ G SK+ ++ + + E +RK+ E E + Sbjct: 119 -EKKERGRTSKEGKERERKEERKRE-------------ERKE--------RERKKEEREK 156 Query: 2496 QRQVPLGGRRGRKDRERERL---EKERTEKERLEREKAERERLE--KLRALEERSDWEGE 2550 +R+ R+ RK RER+++ E+ER EKER ER+K ER R E K R +ER + + E Sbjct: 157 ERE-----RKERKKRERKQVGEKEEERKEKERKERKKRERNRKERKKERERKERRERKKE 211 Query: 2551 GEEDHEGKKEK 2561 ++ E KKE+ Sbjct: 212 RKKKEERKKER 222 Score = 63.2 bits (152), Expect = 7e-09 Identities = 56/257 (21%), Positives = 115/257 (44%), Gaps = 46/257 (17%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332 +++ + ++ + E + +G E+E ER + E E E++ +RG ++ ERKK E Sbjct: 35 QSEIREREREIETRKEGKKERESERKKERREREKRKREREKERKRERGKKEKKGERKKEE 94 Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392 +ER + +++ + E + ++++ E K R + K+G +E +K + ++ Sbjct: 95 RERKKRRREKENKEGEEKEKRKKKEKKERGRTSKEGKERERKEERKREERKER------- 147 Query: 2393 DVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQL 2452 ERK RE+ KE ++++ +G+ +++E E + + ++ Sbjct: 148 -------ERKKEEREKERERKERKKRERKQVGE---------KEEERKEKERKERKKRER 191 Query: 2453 APKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRER 2512 K + E K+ + +RK+ + E +RQ KDR+ Sbjct: 192 NRKERKKERERKERR------ERKK--------ERKKKEERKKERQ---------KDRQT 228 Query: 2513 ERLEKERTEKERLEREK 2529 EKER ++ER ER+K Sbjct: 229 NWREKERGKRERKERKK 245 >gi|78042577 MAP7 domain containing 1 [Homo sapiens] Length = 841 Score = 65.1 bits (157), Expect = 2e-09 Identities = 43/190 (22%), Positives = 98/190 (51%), Gaps = 10/190 (5%) Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324 M ++ A +A+ +A++E E R+ + E+E ++EE + L ++++ R ++A Sbjct: 631 MREEQLAREAEARAEREAEARRRE---EQEAREKAQAEQEEQERLQKQKEEAEARSREEA 687 Query: 2325 LRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANK 2384 R+R +RE K Q+++ Q+ ER+K +E+ +R +K + K++ K++ A Sbjct: 688 ERQRLERE-----KHFQQQE-QERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGS 741 Query: 2385 QVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGL-PLVQDQEDSEGD 2443 P+ V+ + ++++ +E+ + ++ + + + + ++GL PL QE+ Sbjct: 742 SPEPVKAVEARSPGLQKEAVQKEEPIPQEPQWSLPSKELPASLVNGLQPLPAHQENGFST 801 Query: 2444 NSKDPDKQLA 2453 N DK L+ Sbjct: 802 NGPSGDKSLS 811 Score = 41.6 bits (96), Expect = 0.020 Identities = 35/105 (33%), Positives = 61/105 (58%), Gaps = 13/105 (12%) Query: 2271 AMKAQEKAKKEQEERK----HKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALR 2326 A+ A + +QE +K HK A E+ +ER + + ++ L +EEK R ++ L+ Sbjct: 119 AVPASDSPPTKQEVKKAGERHKLAKERREERAKYLAAKKAVWLEKEEKAKALR--EKQLQ 176 Query: 2327 ERKKR-EQERLAKEMQ----EKKLQQELERQKE--EDELKRRVKK 2364 ER++R E++RL E + E++ +Q+LE+ KE E ++R VKK Sbjct: 177 ERRRRLEEQRLKAEQRRAALEERQRQKLEKNKERYEAAIQRSVKK 221 Score = 39.7 bits (91), Expect = 0.078 Identities = 30/151 (19%), Positives = 71/151 (47%), Gaps = 14/151 (9%) Query: 2302 DEEEYDALTEEEKLTFDRGIQQALRERKKREQERLA-----KEMQEKKLQQELE--RQKE 2354 D EE L E++ +QA +R++ EQER K M+E++L +E E ++E Sbjct: 595 DREEATRLLAEKR-------RQAREQREREEQERRLQAERDKRMREEQLAREAEARAERE 647 Query: 2355 EDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKE 2414 + +R ++ ++ E+ ++ Q ++ ++ + + + +ER+ ++Q +E Sbjct: 648 AEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQE 707 Query: 2415 ELNKKKRNMGDVSMHGLPLVQDQEDSEGDNS 2445 + + M + + ++DS+ N+ Sbjct: 708 RRKRLEEIMKRTRKSEVSETKQKQDSKEANA 738 Score = 36.6 bits (83), Expect = 0.66 Identities = 18/75 (24%), Positives = 39/75 (52%) Query: 2487 EEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSD 2546 E+ E + + + RR + RE+ + E+ E+ERL+++K E E + A +R + Sbjct: 634 EQLAREAEARAEREAEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLE 693 Query: 2547 WEGEGEEDHEGKKEK 2561 E ++ + ++E+ Sbjct: 694 REKHFQQQEQERQER 708 Score = 35.8 bits (81), Expect = 1.1 Identities = 47/236 (19%), Positives = 94/236 (39%), Gaps = 31/236 (13%) Query: 2369 PIKEEPPMKKSQAAN------KQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRN 2422 P KE+PP + A PP+T T +R+ + R ++EK +++R Sbjct: 558 PQKEQPPAETPTDAAVLTSPPAPAPPVTPSKPMAGTTDREEATR--LLAEKRRQAREQR- 614 Query: 2423 MGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLP 2482 ++E+ E + DK++ + E + + R++ + Sbjct: 615 -------------EREEQERRLQAERDKRMREEQLAREAEARAEREAEAR--RREEQEAR 659 Query: 2483 PAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKER----TEKERLEREKAERERLEKL 2538 E + Q+Q R R++ ER+RLE+E+ E+ER ER K E +++ Sbjct: 660 EKAQAEQEEQERLQKQKEEAEARSREEAERQRLEREKHFQQQEQERQERRKRLEEIMKRT 719 Query: 2539 RALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQALESDKLPKGEQ 2594 R E + + ++ V ++ ++P GL + + + +P+ Q Sbjct: 720 RKSEVSETKQKQDSKEANANGSSPEPVKAVEARSP---GLQKEAVQKEEPIPQEPQ 772 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 64.7 bits (156), Expect = 2e-09 Identities = 65/301 (21%), Positives = 145/301 (48%), Gaps = 29/301 (9%) Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERLQNMDE--EEYDALTEEEKLTFDRGIQQALRERK 2329 ++ QEK QEE+ H+ +E+E+ Q +E + + + E+E++ + E+ Sbjct: 446 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKI 505 Query: 2330 KREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPI-KEEPPMK------KSQAA 2382 ++++E++ ++ ++ + Q+E R++EE ++ K +Q + +EE M + + Sbjct: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKR 565 Query: 2383 NKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEG 2442 +Q + + + K+ E K+ +E+ + E+EE K++ + +++QE+ Sbjct: 566 QEQEDKMWRQEEKIREQEEKVWRQEEKIREQEE---KRQEQEEKMWKQEEKIREQEEKIQ 622 Query: 2443 DNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD--QRQVP 2500 + + K + E +++ + + + K G Q EE E ++ Q Q Sbjct: 623 EQEE--------KIREQEEKIREQEEMTQEQEEKMGEQ------EEKMCEQEEKMQEQEE 668 Query: 2501 LGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKE 2560 R+ K RE+E+ +E+ EK R E+E+ +E+ EK+ EE+ + E ++ E K Sbjct: 669 TMWRQEEKIREQEKKIREQEEKIR-EQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 727 Query: 2561 K 2561 + Sbjct: 728 R 728 Score = 63.9 bits (154), Expect = 4e-09 Identities = 67/306 (21%), Positives = 139/306 (45%), Gaps = 38/306 (12%) Query: 2263 LNMAQDYAAMKAQEKAKK-----EQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTF 2317 LN Q+ + +EK ++ +++E K + EK +E+ + M +E +EEK+ Sbjct: 294 LNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRR 353 Query: 2318 DRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMK 2377 + E+ +R++E + ++ ++ + Q+E+ +KEE + K +Q I+E+ + Sbjct: 354 QEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKR 413 Query: 2378 KSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQ 2437 + + ++ + + KM E KI +E+ + E+E KK + +H ++++ Sbjct: 414 QEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQE----KKMWRQEEKIHEQEKIREE 469 Query: 2438 EDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD-- 2495 E +Q + E + + + I W +K E HE ++ Sbjct: 470 E----------KRQEQEEMWRQEEKIHEQEEI---WRQK-----------EKMHEQEEKI 505 Query: 2496 QRQVPLGGRRGRKDRERERLEKERTEKERLEREK-AERERL--EKLRALEERSDWEGEGE 2552 ++Q R+ K RE+E +E+ EK + EK E+E + E+ + E+ WE E Sbjct: 506 RKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKR 565 Query: 2553 EDHEGK 2558 ++ E K Sbjct: 566 QEQEDK 571 Score = 63.2 bits (152), Expect = 7e-09 Identities = 69/316 (21%), Positives = 150/316 (47%), Gaps = 57/316 (18%) Query: 2254 IGSREHIYILNMAQDYAAMKAQEKAKKEQEER-KHKGALEKEKERLQNMDEEEY---DAL 2309 I +E I Q+ M QE+ EQEE + K + +++E+++ +E+ + + + Sbjct: 460 IHEQEKIREEEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKI 519 Query: 2310 TEEEKLTFDRGIQQALRERKKREQERLAKEMQ----EKKLQQELERQKEEDELKRRVKKG 2365 E+E+ ++ + +E K REQE + +E + ++K+ +E +RQ++ED++ R+ +K Sbjct: 520 REQEEKIREQEEKMWRQEEKIREQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKI 579 Query: 2366 KQGPIK-----------EEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKE 2414 ++ K EE ++ + KQ + + + K++ E KI +E+ + E+E Sbjct: 580 REQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQE 639 Query: 2415 ELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWD 2474 E + Q+QE+ G+ + +Q K + E T+ W Sbjct: 640 E-----------------MTQEQEEKMGEQEEKMCEQ-EEKMQEQEETM---------WR 672 Query: 2475 RKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERER 2534 +++ ++ + E + +Q ++ +++E + E+ E++ E+E+ +E+ Sbjct: 673 QEEKIREQEKKIREQEEKIREQEEM-------MQEQEEKMWEQ---EEKMCEQEEKMQEQ 722 Query: 2535 LEKLRALEERSDWEGE 2550 EK+R EE+ WE E Sbjct: 723 EEKMRRQEEKM-WEQE 737 Score = 62.0 bits (149), Expect = 1e-08 Identities = 58/286 (20%), Positives = 135/286 (47%), Gaps = 16/286 (5%) Query: 2283 EERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQE 2342 EE K K A +EK +L ++ E +E K +R +++ + E + L KE+Q Sbjct: 217 EELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQS 276 Query: 2343 KKLQQELERQKEEDELKRRVKKGKQGPI--KEEPPMKKSQAANKQVPPLTKVDVKMETIE 2400 + +L+ Q EE+EL R+ + ++ + +EE + + +Q + + + K+ E Sbjct: 277 --VSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQE 334 Query: 2401 RKISVREQTMSEKEELNKKKRNM---GDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFK 2457 K+ +E+ M EKEE +++ M + M + +++ + ++ + K + Sbjct: 335 EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIR 394 Query: 2458 TYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEK 2517 E + + + I +++Q EE ++RQ ++++ RE+ EK Sbjct: 395 ELEEKMHEQEKIREQEEKRQ---------EEEKIREQEKRQEQEAKMWRQEEKIREQEEK 445 Query: 2518 ERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDL 2563 R +++++ R++ + EK+R E+R + E ++ + +++++ Sbjct: 446 IREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491 Score = 41.6 bits (96), Expect = 0.020 Identities = 22/97 (22%), Positives = 56/97 (57%), Gaps = 6/97 (6%) Query: 2265 MAQDYAAMKAQEKAKKEQEE--RKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQ 2322 M + M+ QE+ QEE R+ + + +++E+++ E+ + + E+E+ +++ + Sbjct: 656 MCEQEEKMQEQEETMWRQEEKIREQEKKIREQEEKIR----EQEEMMQEQEEKMWEQEEK 711 Query: 2323 QALRERKKREQERLAKEMQEKKLQQELERQKEEDELK 2359 +E K +EQE + +EK +QE+ +++E++++ Sbjct: 712 MCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQ 748 Score = 37.0 bits (84), Expect = 0.50 Identities = 30/90 (33%), Positives = 47/90 (52%), Gaps = 3/90 (3%) Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324 M + M QE+ +EQE +K + EK +E+ + M E+E +EEK+ Q Sbjct: 663 MQEQEETMWRQEEKIREQE-KKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQE 721 Query: 2325 LRERKKREQERLAKEMQEKKLQQELERQKE 2354 +E K R QE E QE +L+Q+ E+ +E Sbjct: 722 -QEEKMRRQEEKMWE-QEVRLRQQEEKMQE 749 >gi|84043963 eukaryotic translation initiation factor 5B [Homo sapiens] Length = 1220 Score = 64.3 bits (155), Expect = 3e-09 Identities = 82/310 (26%), Positives = 129/310 (41%), Gaps = 72/310 (23%) Query: 2273 KAQEKAKKEQEERK--HKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKK 2330 K EK +KE+E++K K ++ +E L + EEE EEE +R + E K+ Sbjct: 321 KKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEE----ERIKRLEELEAKR 376 Query: 2331 REQERLAKEMQEKKLQQELERQ---KEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387 +E+ERL +E +E+K Q+E ER+ K+E +L K ++ + E +K QA +VP Sbjct: 377 KEEERLEQEKRERKKQKEKERKERLKKEGKL--LTKSQREARARAEATLKLLQAQGVEVP 434 Query: 2388 PLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKD 2447 K+ L KK+ P+ +D++ K Sbjct: 435 ------------------------SKDSLPKKR-----------PIYEDKK------RKK 453 Query: 2448 PDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGG---- 2503 +QL K + + L ++ +QGV P P EP+++ G Sbjct: 454 IPQQLESKEVSESMELCAAVEVM-----EQGV--PEKEETPPPVEPEEEEDTEDAGLDDW 506 Query: 2504 RRGRKDRERERLEKERTE---KERLEREKAERERLEKLRALEERSDWEGEG------EED 2554 D E E++E + KE E E+ E E E+ EE + EGE EED Sbjct: 507 EAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEED 566 Query: 2555 HEGKKEKDLG 2564 + EKD G Sbjct: 567 EKVSDEKDSG 576 Score = 62.4 bits (150), Expect = 1e-08 Identities = 73/324 (22%), Positives = 146/324 (45%), Gaps = 33/324 (10%) Query: 2267 QDYAAMKAQEKAKKE--QEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324 ++ A+K E ++E +++K KG K K+ + D EE + + K T ++ Sbjct: 76 RETVAVKPTENNEEEFTSKDKKKKGQKGK-KQSFDDNDSEELEDKDSKSKKTAKPKVEMY 134 Query: 2325 LRERKKREQERLAKEMQEK--KLQQELERQKEEDELKRRVKK-------GKQGPIKEE-P 2374 + +L K+ + K K ++ + +E+++ +++K+ G+ G +E Sbjct: 135 SGSDDDDDFNKLPKKAKGKAQKSNKKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFL 194 Query: 2375 PMKKSQAANKQVPPLTKVDVKMETIER--KISVREQTMSEKEELNKKKRNMGDVSMHGLP 2432 +K Q N++ P ++ E + KI Q +EK+E +KKR+ + L Sbjct: 195 QSRKGQKKNQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERKKRDEEKAKLRKLK 254 Query: 2433 LVQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHE 2492 ++ E + D SK + Q KF+ + K + + ++ + P A ++ + Sbjct: 255 EKEELETGKKDQSKQKESQ--RKFEEETVKSKVTVDTGVIPASEEKAETPTAAEDDNEGD 312 Query: 2493 PDDQRQVPLGGRRGRKDRER-------------ERLEKERTEKERLEREKAER-ERLEKL 2538 + + G + K++E+ E L K + E+ER +RE+ ER +RLE+L Sbjct: 313 KKKKDKKKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREEEERIKRLEEL 372 Query: 2539 RALEERSDWEGEGEEDHEGKKEKD 2562 A +R + E +E E KK+K+ Sbjct: 373 EA--KRKEEERLEQEKRERKKQKE 394 Score = 36.2 bits (82), Expect = 0.86 Identities = 30/111 (27%), Positives = 53/111 (47%), Gaps = 14/111 (12%) Query: 2268 DYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGI-QQALR 2326 D+ AM + E+ +K + + H E +E + +EEE D +EEE+ + Sbjct: 505 DWEAMASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDE 564 Query: 2327 ERKKREQERLAKEMQEKKLQQEL----------ERQKEE---DELKRRVKK 2364 E +K E+ + + +KK +E+ +R KEE D+ KRR++K Sbjct: 565 EDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAKRRIEK 615 >gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens] Length = 436 Score = 63.2 bits (152), Expect = 7e-09 Identities = 64/302 (21%), Positives = 143/302 (47%), Gaps = 21/302 (6%) Query: 2272 MKAQEKAKKEQEE--RKHKGALEKEKERLQNMD---EEEYDALTEEEKLTFDRGIQQALR 2326 ++ QE +EQE R+ +G + +++ +++ + E+ + E+E ++ Q + Sbjct: 131 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 190 Query: 2327 ERKKREQERLAKEMQEKKLQQELERQKEEDEL----KRRVKKGKQGPIKEEPPMKKSQAA 2382 E + EQE E +E+ +QE + QK+E+++ ++ K+ +Q +EE K+ + Sbjct: 191 EGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQV 250 Query: 2383 NKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEG 2442 KQ + K + +M E ++ +E+ M +++E +++ G+ +++QE+ Sbjct: 251 QKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQ----MREQEEQMR 306 Query: 2443 DNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGM---EEAPHEPDDQRQV 2499 + + +Q + E K + + W++K+ + M EE E ++Q Q Sbjct: 307 EQEEQMREQEEQMREQEEQMGKQEEQM---WEQKEQMWEQKEQMWKQEEQMGEQEEQMQK 363 Query: 2500 PLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKK 2559 + RK E+ R ++E+ K+ + K E + E+ + E+ + E EE +K Sbjct: 364 Q--EEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQK 421 Query: 2560 EK 2561 E+ Sbjct: 422 EQ 423 Score = 60.5 bits (145), Expect = 4e-08 Identities = 60/268 (22%), Positives = 126/268 (47%), Gaps = 29/268 (10%) Query: 2265 MAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQA 2324 M + M QE+ EQEE+ ++K++E+ M E+E +EE++ Q Sbjct: 194 MGEQEGQMGEQEEQMGEQEEQ-----MQKQEEQ---MGEQEEQMRKQEEQMGEQEEQVQK 245 Query: 2325 LRERKKREQERLAKEMQEKKLQQELERQKEEDELKRR--VKKGKQGPIKEEPPMKKSQAA 2382 E+ ++++E++ K+ ++ + Q+E R++EE LK++ ++ +Q +EE ++ + Sbjct: 246 QEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQM 305 Query: 2383 NKQVPPLTKVDVKMETIERKISVREQTM-SEKEELNKKKRNMGDVSMHGLPLVQDQEDSE 2441 +Q + + + +M E ++ +E+ M +KE++ ++K M QE+ Sbjct: 306 REQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQKEQM-----------WKQEEQM 354 Query: 2442 GDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPL 2501 G+ + KQ K E K + + RKQ Q+ EE E +Q Sbjct: 355 GEQEEQMQKQEEQVRKQEEQMRKQEEQM-----RKQEEQM--RKQEEQMGEQKEQMGEQK 407 Query: 2502 GGRRGRKDRERERLEKERTEKERLEREK 2529 R ++++ E+ E+ R ++E + +K Sbjct: 408 EQMREQEEQMGEQKEQMRKQEEHMGEQK 435 Score = 58.5 bits (140), Expect = 2e-07 Identities = 66/305 (21%), Positives = 147/305 (48%), Gaps = 38/305 (12%) Query: 2272 MKAQEKAKKEQEE--RKHKGALEKEKERLQNMD---EEEYDALTEEEKLTFDRGIQQALR 2326 ++ QE +EQE R+ +G + +++ +++ + E+ + E+E ++ Q + Sbjct: 54 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 113 Query: 2327 ERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQ--AANK 2384 E + REQE +E + + +QE + +++E +++ ++G ++E+ + Q + Sbjct: 114 EGQVREQEGQVREQEGQVREQEGQVREQEGQVRE-----QEGQVREQEGQVREQEGQVRE 168 Query: 2385 QVPPLTKVDVKMETIERKISVREQTMSEKE-ELNKKKRNMGDVSMHGLPLVQDQEDSEGD 2443 Q + + + ++ E ++ +E M E+E ++ +++ MG+ +Q QE+ G+ Sbjct: 169 QEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQ----MQKQEEQMGE 224 Query: 2444 NSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGG 2503 + KQ + E K + + +KQ Q+ EE E ++Q Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQV-----QKQEEQM--RKQEEQMREQEEQM------ 271 Query: 2504 RRGRKDRERERLEKERTEKERL--EREKAERERLEKLRALEERSDWEGE---GEEDHEGK 2558 R+ E+ +KE+TE+E E+E+ RE+ E++R EE+ + E +E+ GK Sbjct: 272 ---REQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGK 328 Query: 2559 KEKDL 2563 +E+ + Sbjct: 329 QEEQM 333 Score = 56.6 bits (135), Expect = 6e-07 Identities = 55/278 (19%), Positives = 134/278 (48%), Gaps = 27/278 (9%) Query: 2272 MKAQEKAKKEQEE--RKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERK 2329 ++ QE +EQE R+ +G + +++ ++ +E+ + E+E+ + Q +E + Sbjct: 173 VREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQ----MGEQEEQMQKQEEQMGEQEEQ 228 Query: 2330 KREQERLAKEMQEKKLQQELERQKEEDELKRR---VKKGKQGPIKEEPPMKKSQAANKQV 2386 R+QE E +E+ +QE + QK+E++++++ +++ ++ ++E M K + +Q Sbjct: 229 MRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQE 288 Query: 2387 PPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSK 2446 + + +M E ++ +E+ M E+EE +++QE+ G + Sbjct: 289 EQTGEQEEQMREQEEQMREQEEQMREQEE-----------------QMREQEEQMGKQEE 331 Query: 2447 DPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRG 2506 +Q ++ E K + + ++ Q + EE + ++Q + R Sbjct: 332 QMWEQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRK 391 Query: 2507 RKDRERERLEKERTEKERL-EREKAERERLEKLRALEE 2543 ++++ E+ E+ +KE++ E+E+ E+ E++R EE Sbjct: 392 QEEQMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQEE 429 Score = 49.7 bits (117), Expect = 8e-05 Identities = 57/292 (19%), Positives = 132/292 (45%), Gaps = 27/292 (9%) Query: 2280 KEQEERKHKGALEKEKERLQNMD---EEEYDALTEEEKLTFDRGIQQALRERKKREQERL 2336 +E + R+ +G + +++ +++ + E+ + E+E ++ Q +E + REQE Sbjct: 50 QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQ 109 Query: 2337 AKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKM 2396 +E + + +QE + +++E +++ + +G ++E+ + Q + + + Sbjct: 110 VREQEGQVREQEGQVREQEGQVREQ-----EGQVREQEGQVREQEGQVREQEGQVREQEG 164 Query: 2397 ETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKF 2456 + E++ VREQ +E+ + + G + +QE G+ + +Q Sbjct: 165 QVREQEGQVREQEGQVREQEGQVREQEGQMG--------EQEGQMGEQEEQMGEQEEQMQ 216 Query: 2457 KTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLE 2516 K E + + + RKQ Q+ + E Q+Q ++ + RE+E Sbjct: 217 KQEEQMGEQEEQM-----RKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQM 271 Query: 2517 KERTE-----KERLEREKAERERLEKLRALEER-SDWEGEGEEDHEGKKEKD 2562 +E+ E KE+ E+E+ E+ E++R EE+ + E + E E +E++ Sbjct: 272 REQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQE 323 Score = 48.9 bits (115), Expect = 1e-04 Identities = 66/331 (19%), Positives = 141/331 (42%), Gaps = 24/331 (7%) Query: 2275 QEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQE 2334 +E +K E ++ +E EK +Q + +E E +K+ + Q +E + REQE Sbjct: 7 EELKEKNAELQEELQLVETEKSEIQ-LHIKELKRKLETDKIPLPQEGQVREQEGQVREQE 65 Query: 2335 RLAKEMQEKKLQQ-----ELERQKEEDELKRRVKKG----KQGPIKEEPPMKKSQAANKQ 2385 +E + + +Q E E Q E E + R ++G ++G ++E+ + Q + Sbjct: 66 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 125 Query: 2386 VPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPL------------ 2433 + + + E++ VREQ +E+ + + G V + Sbjct: 126 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 185 Query: 2434 -VQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHE 2492 V++QE G+ +Q + E K + + ++ + + EE + Sbjct: 186 QVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQK 245 Query: 2493 PDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEER-SDWEGEG 2551 ++Q Q R ++++ RE+ E+ R ++E++ ++K + E+ E+ EE+ + E + Sbjct: 246 QEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQM 305 Query: 2552 EEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQ 2582 E E +E++ + + Q E W+Q Sbjct: 306 REQEEQMREQEEQMREQEEQMGKQEEQMWEQ 336 Score = 48.1 bits (113), Expect = 2e-04 Identities = 30/144 (20%), Positives = 85/144 (59%), Gaps = 5/144 (3%) Query: 2272 MKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKR 2331 M+ QE+ +EQEE+ + E+ +E+ + M ++E + + E+++ +++ Q +E + Sbjct: 298 MREQEEQMREQEEQMREQE-EQMREQEEQMGKQE-EQMWEQKEQMWEQKEQMWKQEEQMG 355 Query: 2332 EQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTK 2391 EQE ++ +E+ +QE + +K+E++++++ ++ ++ +EE ++ + +Q + + Sbjct: 356 EQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRK---QEEQMGEQKEQMGEQKEQMRE 412 Query: 2392 VDVKMETIERKISVREQTMSEKEE 2415 + +M + ++ +E+ M E++E Sbjct: 413 QEEQMGEQKEQMRKQEEHMGEQKE 436 >gi|239745153 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 63.2 bits (152), Expect = 7e-09 Identities = 74/312 (23%), Positives = 142/312 (45%), Gaps = 29/312 (9%) Query: 2283 EERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQE 2342 EE K K A +EK RL ++ E ++ K +R +++ + E +RL KE+Q Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ- 272 Query: 2343 KKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERK 2402 + +L+ Q EE+EL + + +EE ++ + +Q + + ++K+ E K Sbjct: 273 -SVSAKLQAQVEENELWNLLNQQ-----QEEKMWRQEEKIQEQEEKMCEQELKIREQEEK 326 Query: 2403 ISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELT 2462 + +E+ M E+EE K R D +++QE+ + +K + K E Sbjct: 327 MWRQEEKMHEQEE---KIREQEDKMWRQEEKIREQEEKIREQE---EKMWRQEEKIREQD 380 Query: 2463 LKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEK 2522 K + W +++ ++ +E + RQ + K RE+E E R E+ Sbjct: 381 EKIQEQEEEMWRQEEKIR-----EQEEKRQEKMWRQEKKMREQDEKIREQEE-EMWRQEE 434 Query: 2523 ERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQ 2582 + E E+ +++ EKLR +EE+ E E ++ E K ++ + + + E +W+Q Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ------EEKIQEQEEKTWRQ 488 Query: 2583 ALESDKLPKGEQ 2594 +KL K E+ Sbjct: 489 ----EKLLKQEE 496 Score = 61.2 bits (147), Expect = 2e-08 Identities = 78/332 (23%), Positives = 155/332 (46%), Gaps = 28/332 (8%) Query: 2262 ILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGI 2321 +LN Q+ + +EK + EQEE+ + L K +E+ + M +E +EEK+ ++ Sbjct: 290 LLNQQQEEKMWRQEEKIQ-EQEEKMCEQEL-KIREQEEKMWRQEEKMHEQEEKIR-EQED 346 Query: 2322 QQALRERKKREQERLAKEMQEKKLQQELE--------RQKEEDELKRRVKKGKQGPIKEE 2373 + +E K REQE +E +EK +QE + +++EE+ ++ K +Q ++E Sbjct: 347 KMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQE 406 Query: 2374 PPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPL 2433 ++ + +Q + + + +M E KI E+ M ++EE K R + + Sbjct: 407 KMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE---KLREVEEKMQEEEEK 463 Query: 2434 VQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGM---EEAP 2490 +Q+QE+ + ++ ++ K E LK + I W++++ + M EE Sbjct: 464 MQEQEE-KIQRQEEKIQEQEEKTWRQEKLLKQEEKI---WEQEEKMWRQEEKMWEQEEKM 519 Query: 2491 HEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGE 2550 E +++ Q R+ K RE+E + + E++ E+E +E E+L L ++++ G Sbjct: 520 QEQEEKMQ-----RQEEKMREQE-VRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLG- 572 Query: 2551 GEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQ 2582 G G + P L ++ E S +Q Sbjct: 573 GAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604 Score = 57.4 bits (137), Expect = 4e-07 Identities = 55/283 (19%), Positives = 135/283 (47%), Gaps = 4/283 (1%) Query: 2263 LNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQ 2322 L + Q ++A K+ Q A +E E +++++ + + +E+ ++ + Sbjct: 253 LLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEK 312 Query: 2323 QALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAA 2382 +E K REQE +EK +QE + +++ED++ R+ +K ++ +EE ++ + Sbjct: 313 MCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE---QEEKIREQEEKM 369 Query: 2383 NKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEG 2442 +Q + + D K++ E ++ +E+ + E+EE ++K + M +++ E Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429 Query: 2443 DNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLG 2502 ++ ++L + E L++V+ + + K Q +E + +++ Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489 Query: 2503 GRRGRKDRERERLEKE-RTEKERLEREKAERERLEKLRALEER 2544 ++++ E+ EK R E++ E+E+ +E+ EK++ EE+ Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532 >gi|239745127 PREDICTED: similar to Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 655 Score = 63.2 bits (152), Expect = 7e-09 Identities = 74/312 (23%), Positives = 142/312 (45%), Gaps = 29/312 (9%) Query: 2283 EERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKREQERLAKEMQE 2342 EE K K A +EK RL ++ E ++ K +R +++ + E +RL KE+Q Sbjct: 214 EELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQ- 272 Query: 2343 KKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKVDVKMETIERK 2402 + +L+ Q EE+EL + + +EE ++ + +Q + + ++K+ E K Sbjct: 273 -SVSAKLQAQVEENELWNLLNQQ-----QEEKMWRQEEKIQEQEEKMCEQELKIREQEEK 326 Query: 2403 ISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAPKFKTYELT 2462 + +E+ M E+EE K R D +++QE+ + +K + K E Sbjct: 327 MWRQEEKMHEQEE---KIREQEDKMWRQEEKIREQEEKIREQE---EKMWRQEEKIREQD 380 Query: 2463 LKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEK 2522 K + W +++ ++ +E + RQ + K RE+E E R E+ Sbjct: 381 EKIQEQEEEMWRQEEKIR-----EQEEKRQEKMWRQEKKMREQDEKIREQEE-EMWRQEE 434 Query: 2523 ERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQ 2582 + E E+ +++ EKLR +EE+ E E ++ E K ++ + + + E +W+Q Sbjct: 435 KIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ------EEKIQEQEEKTWRQ 488 Query: 2583 ALESDKLPKGEQ 2594 +KL K E+ Sbjct: 489 ----EKLLKQEE 496 Score = 61.2 bits (147), Expect = 2e-08 Identities = 78/332 (23%), Positives = 155/332 (46%), Gaps = 28/332 (8%) Query: 2262 ILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGI 2321 +LN Q+ + +EK + EQEE+ + L K +E+ + M +E +EEK+ ++ Sbjct: 290 LLNQQQEEKMWRQEEKIQ-EQEEKMCEQEL-KIREQEEKMWRQEEKMHEQEEKIR-EQED 346 Query: 2322 QQALRERKKREQERLAKEMQEKKLQQELE--------RQKEEDELKRRVKKGKQGPIKEE 2373 + +E K REQE +E +EK +QE + +++EE+ ++ K +Q ++E Sbjct: 347 KMWRQEEKIREQEEKIREQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQE 406 Query: 2374 PPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPL 2433 ++ + +Q + + + +M E KI E+ M ++EE K R + + Sbjct: 407 KMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEE---KLREVEEKMQEEEEK 463 Query: 2434 VQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGM---EEAP 2490 +Q+QE+ + ++ ++ K E LK + I W++++ + M EE Sbjct: 464 MQEQEE-KIQRQEEKIQEQEEKTWRQEKLLKQEEKI---WEQEEKMWRQEEKMWEQEEKM 519 Query: 2491 HEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGE 2550 E +++ Q R+ K RE+E + + E++ E+E +E E+L L ++++ G Sbjct: 520 QEQEEKMQ-----RQEEKMREQE-VRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLG- 572 Query: 2551 GEEDHEGKKEKDLGVPFLDIQTPDFEGLSWKQ 2582 G G + P L ++ E S +Q Sbjct: 573 GAGRESGSQRLPTLTPILQVELKSQEAQSLQQ 604 Score = 57.4 bits (137), Expect = 4e-07 Identities = 55/283 (19%), Positives = 135/283 (47%), Gaps = 4/283 (1%) Query: 2263 LNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQ 2322 L + Q ++A K+ Q A +E E +++++ + + +E+ ++ + Sbjct: 253 LLLPQQQLQVEADRLGKELQSVSAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEK 312 Query: 2323 QALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAA 2382 +E K REQE +EK +QE + +++ED++ R+ +K ++ +EE ++ + Sbjct: 313 MCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIRE---QEEKIREQEEKM 369 Query: 2383 NKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEG 2442 +Q + + D K++ E ++ +E+ + E+EE ++K + M +++ E Sbjct: 370 WRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEM 429 Query: 2443 DNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLG 2502 ++ ++L + E L++V+ + + K Q +E + +++ Sbjct: 430 WRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWRQE 489 Query: 2503 GRRGRKDRERERLEKE-RTEKERLEREKAERERLEKLRALEER 2544 ++++ E+ EK R E++ E+E+ +E+ EK++ EE+ Sbjct: 490 KLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEK 532 >gi|22758136 MAP7 domain containing 2 [Homo sapiens] Length = 732 Score = 62.4 bits (150), Expect = 1e-08 Identities = 51/160 (31%), Positives = 81/160 (50%), Gaps = 21/160 (13%) Query: 2266 AQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQAL 2325 A+ A + Q + +KEQEE++ EKE ++ EE EEE+L + ++ Sbjct: 401 AKILAEKRRQARLQKEQEEQERV-----EKEEQDRLEREELKRKAEEERLRLEEEARKQE 455 Query: 2326 RERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPM--KKSQAAN 2383 ERK++E+E+ +E +EK+ E ++K E+EL + K KQ K+E M K+ +AA Sbjct: 456 EERKRQEEEKKKQEGEEKRKAGEEAKRKAEEEL---LLKEKQEQEKQEKAMIEKQKEAAE 512 Query: 2384 KQVPPLTKVDVKMETIERKISVREQTM--SEKEELNKKKR 2421 + E E+ REQ M E+E L +KKR Sbjct: 513 TKA---------REVAEQMRLEREQIMLQIEQERLERKKR 543 Score = 42.7 bits (99), Expect = 0.009 Identities = 38/128 (29%), Positives = 63/128 (49%), Gaps = 21/128 (16%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332 KA E+AK++ EE L KEK+ E++ A+ E++K + + R+ E Sbjct: 475 KAGEEAKRKAEEE----LLLKEKQEQ----EKQEKAMIEKQKEAAE------TKAREVAE 520 Query: 2333 QERLAKEMQEKKLQQE-LERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTK 2391 Q RL +E +++QE LER+K DE+ +R +K + PP K + V P Sbjct: 521 QMRLEREQIMLQIEQERLERKKRIDEIMKRTRK------SDVPPQVKKEDPKVGVQPAVC 574 Query: 2392 VDVKMETI 2399 V+ K + + Sbjct: 575 VEKKTKLV 582 Score = 42.0 bits (97), Expect = 0.016 Identities = 55/277 (19%), Positives = 115/277 (41%), Gaps = 67/277 (24%) Query: 2275 QEKAKKEQEERKHKGALEKEKERLQN---MDEEEYDALTEEEKLTFDRGIQQALRERKK- 2330 + KA+KE+ ++ +G L ++ Q +++ D E+ G + K Sbjct: 331 KRKAEKEKSNKEREGTLAQQAAGPQGEEALEKHVVDKHASEKHAAAAGGKAENSAALGKP 390 Query: 2331 ----REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQV 2386 + AK + EK+ Q L++++EE E RV+K +Q ++ E +K++ Sbjct: 391 TAGTTDAGEAAKILAEKRRQARLQKEQEEQE---RVEKEEQDRLEREELKRKAE------ 441 Query: 2387 PPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSK 2446 E ++ + E+ ++EE +++ ++++ EG+ + Sbjct: 442 -------------EERLRLEEEARKQEEERKRQE--------------EEKKKQEGEEKR 474 Query: 2447 DPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRG 2506 ++ K + EL LK+ Q +E + ++Q + Sbjct: 475 KAGEEAKRKAEE-ELLLKEKQE------------------QEKQEKAMIEKQKEAAETKA 515 Query: 2507 RKDRERERLEKE----RTEKERLEREKAERERLEKLR 2539 R+ E+ RLE+E + E+ERLER+K E +++ R Sbjct: 516 REVAEQMRLEREQIMLQIEQERLERKKRIDEIMKRTR 552 Score = 40.4 bits (93), Expect = 0.046 Identities = 31/90 (34%), Positives = 47/90 (52%), Gaps = 9/90 (10%) Query: 2482 PPAGMEEAPHEPDDQRQVPLGGRRGRKDRERERLEKERTEKERLERE----KAERERL-- 2535 P AG +A + R ++ E+ER+EKE E++RLERE KAE ERL Sbjct: 390 PTAGTTDAGEAAKILAEKRRQARLQKEQEEQERVEKE--EQDRLEREELKRKAEEERLRL 447 Query: 2536 -EKLRALEERSDWEGEGEEDHEGKKEKDLG 2564 E+ R EE + E ++ EG++++ G Sbjct: 448 EEEARKQEEERKRQEEEKKKQEGEEKRKAG 477 >gi|55741709 RNA binding motif protein 25 [Homo sapiens] Length = 843 Score = 61.6 bits (148), Expect = 2e-08 Identities = 62/296 (20%), Positives = 134/296 (45%), Gaps = 28/296 (9%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332 + +EK K+ + ER+ ++ KER ++ D E D + E+ + DR ++ K R+ Sbjct: 333 REREKEKERERERERDRDRDRTKERDRDRDRER-DRDRDRERSS-DRNKDRSRSREKSRD 390 Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392 +ER + +E++ ++E ER++E + + R ++ ++ K+ + + A ++ K+ Sbjct: 391 REREREREREREREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKL 450 Query: 2393 DVKMETIERKIS---VREQTMS-----EKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDN 2444 K + ++ +RE+ + E E +++R M + ++D +D D Sbjct: 451 REKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDD- 509 Query: 2445 SKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGR 2504 PK+ K ++ DR++ ++ + E ++ RQ L Sbjct: 510 ---------PKYYRGSALQKRLR------DREKEMEADERDRKREKEELEEIRQRLLAEG 554 Query: 2505 RGRKDRERERLEK--ERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGK 2558 D E +R+E+ ER + ++++E E E+ + EE+ + E EE+ E K Sbjct: 555 HPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQK 610 Score = 58.5 bits (140), Expect = 2e-07 Identities = 77/366 (21%), Positives = 153/366 (41%), Gaps = 64/366 (17%) Query: 2256 SREHIYILNMAQDYAAMKAQEKAK-----KEQEERKHKGALEKEKERLQNMDEEEYDALT 2310 ++E I + M +D + ++E +K K+ EE K K KEKER Q +++E + Sbjct: 260 TKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGK----KEKER-QEIEKERRERER 314 Query: 2311 EEEKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPI 2370 E E RER++RE+ER + +E++ ++E ER++E D + R K+ + Sbjct: 315 ERE------------RERERREREREREREREREKEKERERERERDRDRDRTKERDRDRD 362 Query: 2371 KEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHG 2430 +E + + ++ + ++ K ER+ + E+E +++R Sbjct: 363 RERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERE 422 Query: 2431 LPLVQDQEDSEGDNSKDP------DKQLAPKFKTYELTLKDVQ------------NILMY 2472 +D++ ++ +D +++L K Y+ LK+ + Sbjct: 423 REREKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAERE 482 Query: 2473 WDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGR-----RGRKDRERERLEKERTEKERLER 2527 +R++ + ++E + DD R P R + +DRE+E ER K E Sbjct: 483 EERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEE 542 Query: 2528 EKAERERL-------------------EKLRALEERSDWEGEGEEDHEGKKEKDLGVPFL 2568 + R+RL E+ R + + + E E EE+ + +KE+ P Sbjct: 543 LEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPME 602 Query: 2569 DIQTPD 2574 + + P+ Sbjct: 603 EEEEPE 608 Score = 53.5 bits (127), Expect = 5e-06 Identities = 47/189 (24%), Positives = 88/189 (46%), Gaps = 17/189 (8%) Query: 2378 KSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEEL----NKKKRNMGDVSMHGLPL 2433 K +A+N P T + E ++ + R+Q + E+ + N P Sbjct: 175 KKKASNGNARPETVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPR 234 Query: 2434 VQDQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEP 2493 + +E E + P +AP +T +D+ I M D++ + + + + Sbjct: 235 KKKKEKKEDIFRRFP---VAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKL 291 Query: 2494 DDQRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEGEE 2553 ++++ G+K++ER+ +EKER E+ER ERE+ ERER E+ R E + E E E Sbjct: 292 EEEK--------GKKEKERQEIEKERRERER-ERER-ERERREREREREREREREKEKER 341 Query: 2554 DHEGKKEKD 2562 + E ++++D Sbjct: 342 ERERERDRD 350 Score = 52.4 bits (124), Expect = 1e-05 Identities = 63/310 (20%), Positives = 129/310 (41%), Gaps = 21/310 (6%) Query: 2260 IYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDR 2319 ++ L + + +K K K + +E K K R + + ++ +AL EE K D+ Sbjct: 147 LHDLQIGEKKLLVKVDAKTKAQLDEWKAKKKASNGNARPETVTNDDEEALDEETKRR-DQ 205 Query: 2320 GIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKS 2379 I+ A+ + L QE +++++++++ RR P+ P + K Sbjct: 206 MIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFRRFPVA---PLIPYPLITK- 261 Query: 2380 QAANKQVPPLTKVDVKMETIERKISVREQTMSE-KEELNKKKRNMGDVSMHGLPLVQDQE 2438 + + + + K + I R+IS T + +EE KK++ ++ +++E Sbjct: 262 ----EDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERE 317 Query: 2439 DSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQ 2498 ++ +++ + + + ++ + DR + + E + D +R Sbjct: 318 RERERREREREREREREREKEKERERERERDR---DRDRTKERDRDRDRERDRDRDRERS 374 Query: 2499 VPLGGRRGR-------KDRERERLEKERTEKERLEREKAERERLEKLRALEERSDWEGEG 2551 R R ++RERER + E+ER + ERER E+ R E D + + Sbjct: 375 SDRNKDRSRSREKSRDRERERERERERERERERERERERERER-EREREREREKDKKRDR 433 Query: 2552 EEDHEGKKEK 2561 EED E E+ Sbjct: 434 EEDEEDAYER 443 Score = 51.2 bits (121), Expect = 3e-05 Identities = 56/300 (18%), Positives = 131/300 (43%), Gaps = 57/300 (19%) Query: 2273 KAQEKAKKEQEERKHKGA-------LEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQAL 2325 + ++K KKE R+ A + KE M+E++ D ++ E ++ R + L Sbjct: 234 RKKKKEKKEDIFRRFPVAPLIPYPLITKEDINAIEMEEDKRDLISRE--ISKFRDTHKKL 291 Query: 2326 RE---RKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAA 2382 E +K++E++ + KE +E++ ++E ER++ E E +R ++ ++ + E ++ + Sbjct: 292 EEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKERERERERDRDR 351 Query: 2383 NKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEG 2442 ++ TK + ER R++ + NK + + S + + + E Sbjct: 352 DR-----TKERDRDRDRERD---RDRDRERSSDRNKDRSRSREKSRDRERERERERERER 403 Query: 2443 DNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLG 2502 + ++ +++ E E + +R+ Sbjct: 404 ERERERERE-----------------------------------REREREREREREREKD 428 Query: 2503 GRRGRKDRERERLEKERTEKERLEREKAERERLE--KLRALEERSDWEGEGEEDHEGKKE 2560 +R R++ E + E+ + E++ E+E A +ERL+ ++R ++ ++E E E + E ++E Sbjct: 429 KKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRRE 488 Score = 42.0 bits (97), Expect = 0.016 Identities = 33/152 (21%), Positives = 73/152 (48%), Gaps = 35/152 (23%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKK-- 2330 K +E K+ + E + + + KE +RL+ E+YD ++ K +Q+ LR+R+K Sbjct: 471 KTREYEKEAEREEERRREMAKEAKRLKEF-LEDYDDDRDDPKYYRGSALQKRLRDREKEM 529 Query: 2331 ----REQERLAKEMQE-----------------KKLQQELERQK-----------EEDEL 2358 R+++R +E++E ++++QE ER++ EE+E Sbjct: 530 EADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEE 589 Query: 2359 KRRVKKGKQGPIKEEPPMKKSQAANKQVPPLT 2390 K+ ++ ++ P++EE ++ + P++ Sbjct: 590 KQEKEEKREEPMEEEEEPEQKPCLKPTLRPIS 621 Score = 37.4 bits (85), Expect = 0.39 Identities = 27/115 (23%), Positives = 56/115 (48%), Gaps = 4/115 (3%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332 + +E E++ ++ K LE+ ++RL + DA + + +R Q +++ + E Sbjct: 525 REKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERRRQPQIKQEPESE 584 Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVP 2387 +E +E QEK+ ++E ++EE+ ++ K PI P + S A+ P Sbjct: 585 EEE--EEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSV--SSASGNATP 635 >gi|83035129 coiled-coil domain containing 108 isoform 1 [Homo sapiens] Length = 1925 Score = 60.8 bits (146), Expect = 3e-08 Identities = 53/242 (21%), Positives = 99/242 (40%), Gaps = 19/242 (7%) Query: 120 LILRNNDKIPRLVKVVEESSPYFKVISPKDIGHKVAPGVPSIFRILFTPEENKDYAHTLT 179 L+L+N + +K + +F + P+ I ++PG+ I+F P E K+Y L Sbjct: 166 LVLKNRSLKLQKMKYRPPKTKFFFTVIPQPIF--LSPGITLTLPIVFRPLEAKEYMDQLW 223 Query: 180 CVTEREKFIVPIKAR-GARAILDFPDKLNFSTCPVKYSTQKILLVRNIGNKNAVFHIKTC 238 F V ++A ++ P L C V +T+ + N+G+ F + Sbjct: 224 FEKAEGMFCVGLRATLPCHRLICRPPSLQLPMCAVGDTTEAFFCLDNVGDLPTFFTWEFS 283 Query: 239 RPFSIEPAIGTLNVGESMQLEVEFEPQSVGDHSGRLIVCYDTGEKVFVSLYGAAI----- 293 PF + PA G L G++ Q++V F+P + + + Y G + S+ A+ Sbjct: 284 SPFQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKCAQ 343 Query: 294 -----------DMNIRLDKNSLTIEKTYISLANQRTITIHNRSNIIAHFLWKVFATQQEE 342 D + + L + ++R I +HN S + A F ++ + E Sbjct: 344 LLVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDELAE 403 Query: 343 DR 344 D+ Sbjct: 404 DQ 405 Score = 57.8 bits (138), Expect = 3e-07 Identities = 59/276 (21%), Positives = 111/276 (40%), Gaps = 25/276 (9%) Query: 4366 VVKPGNTLEIPITFYPRESINY--QELIPFEINGLSQQTVEIKGKGTKMKILV------- 4416 +++PG +I +TF P ++ Y Q + + +++++ ++LV Sbjct: 294 LLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKCAQLLVSIKHKCP 353 Query: 4417 ----LDPANRIVKLGAVLPGQVVKRTVSIMNNSLAQLTFNQSILFTIPELQEPKVLTLAP 4472 + +++ G+V G +R + + N S F I + EL E + + Sbjct: 354 EDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEI--SPDELAEDQAFSCPT 411 Query: 4473 FHNITLKPKEVCKLEVIFAPKK---RVPPFSEEVFMECMGLLRPLFLLSGCCQALEISLD 4529 H I L ++ C + V F PK R + + C + L + G C+ +SL Sbjct: 412 AHGIVLPGEKKC-VSVFFHPKTLDTRTVDYCSIMPSGCAS--KTLLKVVGFCRGPAVSLQ 468 Query: 4530 QEHIPFGPVVYQTQATRRILMMNTGDVGARFKWDIKKFEPHFSISPEEGYITSGMEVSFE 4589 + F V ++ + + + N D A F++ I E F+I P G + ++ Sbjct: 469 HYCVNFSWVNLGERSEQPLWIENQSDCTAHFQFAIDCLESVFTIRPAFGTLVGKARMTLH 528 Query: 4590 VTYHPTEVGKESLC-KNILCYIQGGSPLSLTLSGVC 4624 + PT +C + + C I PL L L G C Sbjct: 529 CAFQPTH---PIICFRRVACLIHHQDPLFLDLMGTC 561 Score = 48.9 bits (115), Expect = 1e-04 Identities = 56/234 (23%), Positives = 98/234 (41%), Gaps = 19/234 (8%) Query: 3888 PFSVEPSSGIVPVGKIQKFKVKFSPLDIGDFESNLFCQIPNLPPGEQGPVLVAKGRSTLP 3947 PF + P++G++ G+ + KV F PL +E C ++ RS++ Sbjct: 285 PFQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYG----------AGSRQRSSIQ 334 Query: 3948 ICHFDLKDSDYISGHQRNPELRGSSGGALDPNTRVIEFTTVGIGGKNLRTFTILNPTNST 4007 + +S + PE + + G +++ F +V +G + R + NP+ Sbjct: 335 LQAVAKCAQLLVSIKHKCPEDQDAEGFQ-----KLLYFGSVAVGCTSERQIRLHNPSAVN 389 Query: 4008 YSFCWISEEIESLQNPAAFTCLTEKGFIHP-EKKAEIVFQFTPFHLGITESSWTFLIPEH 4066 F I + L AF+C T G + P EKK VF F P L + ++P Sbjct: 390 APFR-IEISPDELAEDQAFSCPTAHGIVLPGEKKCVSVF-FHPKTLDTRTVDYCSIMPSG 447 Query: 4067 NITVPFL-LVGKTTEPLISLNKSHLNFSSLLIGREARETVQIINKEEQGFDFSF 4119 + L +VG P +SL +NFS + +G + + + I N+ + F F Sbjct: 448 CASKTLLKVVGFCRGPAVSLQHYCVNFSWVNLGERSEQPLWIENQSDCTAHFQF 501 Score = 39.7 bits (91), Expect = 0.078 Identities = 40/169 (23%), Positives = 73/169 (43%), Gaps = 20/169 (11%) Query: 4256 SPIDSTVDVGQSVHATLSFQPLKKCVLTD-LELIIKISHGPTFMCNISGCAVSPA---IH 4311 SP ++ GQ L + L + TD L ++ K+SHG + N G V P +H Sbjct: 1241 SPKAGSLSPGQEQMVELKYSHL--FIGTDHLPVLFKVSHGREILLNFIGVTVKPEQKYVH 1298 Query: 4312 FSFTSYNFGTCFIYQAGMPPYKQTLVITNKEETPMSIDCLYTNTTHLE-----------V 4360 F+ T++ F I +PP +Q + N P++ + + ++ + Sbjct: 1299 FTSTTHQFIPIPIGDT-LPP-RQIYELYNGGSVPVTYEVQTDVLSQVQEKNFDHPIFCCL 1356 Query: 4361 NSRVDVVKPGNTLEIPITFYPRESINYQELIPFEINGLSQQTVEIKGKG 4409 N + ++ +PG+T + F P E+ Y +P I G + + +G G Sbjct: 1357 NPKGEI-QPGSTARVLWIFSPIEAKTYTVDVPIHILGWNSALIHFQGVG 1404 Score = 39.3 bits (90), Expect = 0.10 Identities = 32/130 (24%), Positives = 59/130 (45%), Gaps = 20/130 (15%) Query: 2252 KAIGSREHIYILNMAQDYAAMKAQEKAKKEQEER-KHKGALEKEKERLQNMDEEEYDALT 2310 K + + +Y++ + ++ K K+ +E+R +H L K++E + EEE + L Sbjct: 1717 KFMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELE 1776 Query: 2311 EEEKLTFDRGIQQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPI 2370 EEE+ E ++ E+E L KE E E+++E DE + +V GP Sbjct: 1777 EEEE------------EEEETEEEELGKEEIE-------EKEEERDEKEEKVSWAGIGPT 1817 Query: 2371 KEEPPMKKSQ 2380 + + Q Sbjct: 1818 PQPESQESMQ 1827 Score = 36.6 bits (83), Expect = 0.66 Identities = 33/149 (22%), Positives = 64/149 (42%), Gaps = 21/149 (14%) Query: 1329 FDILPLFGVLQPHSSHQISFTFYGHANIIAQAKALCEVEEGPTYEITLKGEA-------- 1380 F +LP G+L+P + QI TF +I + +A C G +++ +A Sbjct: 286 FQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKCAQLL 345 Query: 1381 -SLVNYSFDTKD-------IHYGLQLFDHVTEREITLTNMGKVGFEFKVLTDHQSSPDNL 1432 S+ + + +D +++G +ER+I L N V F++ + SPD L Sbjct: 346 VSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRI----EISPDEL 401 Query: 1433 LPGVPLILPVS-GFISSHQEQVLKVYYLP 1460 P + G + +++ + V++ P Sbjct: 402 AEDQAFSCPTAHGIVLPGEKKCVSVFFHP 430 Score = 35.4 bits (80), Expect = 1.5 Identities = 42/199 (21%), Positives = 78/199 (39%), Gaps = 18/199 (9%) Query: 400 FNNVFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQ--------------QTIYCDILGRE 445 F++ F + P G + P +++I V F PL A +Y+ +I + + Sbjct: 282 FSSPFQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWYGAGSRQRSSIQLQAVAKC 341 Query: 446 IRLPLRIKGEGMGPKIHFNFE-LLDIGKVFTGSAHCYEAILYNKGSIDALF--NMTPPTS 502 +L + IK + + F+ LL G V G + L+N +++A F ++P Sbjct: 342 AQLLVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDEL 401 Query: 503 ALGACFVFSPKEGIIEPSGVQAIQISFSSTILGNFEEEFL-VNVNGSPEPVKLTIRGCVI 561 A F GI+ P + + + F L ++ + +G L + G Sbjct: 402 AEDQAFSCPTAHGIVLPGEKKCVSVFFHPKTLDTRTVDYCSIMPSGCASKTLLKVVGFCR 461 Query: 562 GPTFHFNVPALHFGDVSFG 580 GP ++F V+ G Sbjct: 462 GPAVSLQHYCVNFSWVNLG 480 Score = 35.4 bits (80), Expect = 1.5 Identities = 55/235 (23%), Positives = 93/235 (39%), Gaps = 20/235 (8%) Query: 640 FTISPDCGTIRPQGFAAIRVTLCSNTVQKYELALVVDVEGIGE------EVLALLITARC 693 F + P G + P + I+VT T YE+ G G ++ A+ A+ Sbjct: 286 FQMLPATGLLEPGQASQIKVTFQPLTAVIYEVQATCWY-GAGSRQRSSIQLQAVAKCAQL 344 Query: 694 VVPALHLVNTEVD---------FGHCFLKYPYEKTLQLANQDDLPGFYEVQPQVCEEVPT 744 +V H + D FG + E+ ++L N + + ++ E Sbjct: 345 LVSIKHKCPEDQDAEGFQKLLYFGSVAVGCTSERQIRLHNPSAVNAPFRIEISPDELAED 404 Query: 745 VLFSSPTPSGVISPSSTIHIPLVLETQVTGEHRSTVYISIFGSQDPPLVCHLKSAG--EG 802 FS PT G++ P + + + T + R+ Y SI S LK G G Sbjct: 405 QAFSCPTAHGIVLPGEKKCVSVFFHPK-TLDTRTVDYCSIMPSGCASKTL-LKVVGFCRG 462 Query: 803 PVIYVHPNQVDFGNIYVLKDSSRILNLCNQSFIPAFFQAHMAHKKSLWTIEPNEG 857 P + + V+F + + + S + L + NQS A FQ + +S++TI P G Sbjct: 463 PAVSLQHYCVNFSWVNLGERSEQPLWIENQSDCTAHFQFAIDCLESVFTIRPAFG 517 Score = 35.4 bits (80), Expect = 1.5 Identities = 22/69 (31%), Positives = 34/69 (49%), Gaps = 1/69 (1%) Query: 391 LVQGDSKLFFNNVFTVEPLEGDVWPNSSAEITVYFNPLEAKLYQQTIYCDILGREIRLPL 450 L Q K F + +F +G++ P S+A + F+P+EAK Y + ILG L + Sbjct: 1340 LSQVQEKNFDHPIFCCLNPKGEIQPGSTARVLWIFSPIEAKTYTVDVPIHILGWNSAL-I 1398 Query: 451 RIKGEGMGP 459 +G G P Sbjct: 1399 HFQGVGYNP 1407 Score = 34.3 bits (77), Expect = 3.3 Identities = 34/141 (24%), Positives = 55/141 (39%), Gaps = 28/141 (19%) Query: 2472 YWDRKQGVQLPPA----------GMEEAPHEPDDQRQVPLG----GRRGRKDRERERLEK 2517 + D+K + L P G + P E + LG G + + E E LE+ Sbjct: 1718 FMDQKNSLYLMPILPVPSSSWEDGKGKQPKEDRPEHYPGLGKKEEGEEEKGEEEEEELEE 1777 Query: 2518 ERTEKERLEREKAERERLEKLRALEERSDWEGEGEEDHEGKKEKDLGVPFLDIQTPDF-E 2576 E E+E E E+ +E +E E EE+ + K+EK P+ E Sbjct: 1778 EEEEEEETEEEELGKEEIE-------------EKEEERDEKEEKVSWAGIGPTPQPESQE 1824 Query: 2577 GLSWKQALESDKLPKGEQILD 2597 + W+ + + + K EQ D Sbjct: 1825 SMQWQWQQQLNVMVKEEQEQD 1845 >gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens] Length = 1293 Score = 60.5 bits (145), Expect = 4e-08 Identities = 63/272 (23%), Positives = 127/272 (46%), Gaps = 36/272 (13%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332 +A+ +AK+E+EERK + L +++E + +EE EEE+L R ++ALR ++RE Sbjct: 737 EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA-RRKQEEALR--RQRE 793 Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392 QE + +E++ ERQ++E+ L+R ++ ++ EE K+ + KQ K Sbjct: 794 QEIALRRQREEE-----ERQQQEEALRRLEERRRE----EEERRKQEELLRKQEEEAAKW 844 Query: 2393 DVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQL 2452 + E +R++ E + +EE + + +++E + K+L Sbjct: 845 AREEEEAQRRL--EENRLRMEEEAARLRH-------------EEEERKRKELEVQRQKEL 889 Query: 2453 APKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRER 2512 + + + L+ +Q ++Q QL + + + E Sbjct: 890 MRQRQQQQEALRRLQ------QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 943 Query: 2513 ERLEKERTEKERLEREKAERERLEKLRALEER 2544 ++LE+ER ER RE+ R++ E ++AL+++ Sbjct: 944 QKLEEER---ERQLREEQRRQQRELMKALQQQ 972 Score = 45.8 bits (107), Expect = 0.001 Identities = 38/176 (21%), Positives = 81/176 (46%), Gaps = 14/176 (7%) Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLT 2316 RE L ++ + QE+A + EER+ + +++E L EEE EE+ Sbjct: 792 REQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEA 851 Query: 2317 FDRGIQQALRERKK------REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQG-- 2368 R + LR ++ E+ER KE++ ++ ++ + +++++ E RR+++ +Q Sbjct: 852 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQ 911 Query: 2369 ------PIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNK 2418 P + + A + L+ +++ ER+ +RE+ ++ EL K Sbjct: 912 LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMK 967 Score = 45.4 bits (106), Expect = 0.001 Identities = 48/279 (17%), Positives = 119/279 (42%), Gaps = 22/279 (7%) Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLT 2316 +E I ++ + +E A+++QEE + ++E+E EE + +EE L Sbjct: 759 QEEILRRQQEEERKRREEEELARRKQEEALRR---QREQEIALRRQREEEERQQQEEAL- 814 Query: 2317 FDRGIQQALRERKKREQERLAKEMQEKKLQQELER-QKEEDELKRRVKKGKQGPIKEEPP 2375 + L ER++ E+ER +E +K ++E + +EE+E +RR+++ + +E Sbjct: 815 ------RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 868 Query: 2376 MKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQ 2435 ++ + K+ K ++R+ + Q ++E L + ++ + + L Sbjct: 869 LRHEEEERKR---------KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPS 919 Query: 2436 DQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD 2495 + N+ Q + ++ + L R+Q +L A ++ + Sbjct: 920 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQ--QQQQQ 977 Query: 2496 QRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERER 2534 Q+ G + LE ++ E ++++++ ++++ Sbjct: 978 QKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1016 Score = 38.9 bits (89), Expect = 0.13 Identities = 64/291 (21%), Positives = 124/291 (42%), Gaps = 39/291 (13%) Query: 2287 HKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGI-----QQALRERKK-----REQERL 2336 H G L++E+ Q +E AL + + L + + + Q L +++K ++Q++L Sbjct: 595 HMGELDQERLTRQ----QELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQL 650 Query: 2337 AKEMQE-KKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV-DV 2394 A +Q+ + L+ + Q + R V G I E P A+ V V D+ Sbjct: 651 ALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPT----ASQPTVWEGGSVWDL 706 Query: 2395 KMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAP 2454 ++T ++ + EK + K ++ + M +++E + + +++ Sbjct: 707 PLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKR--EEEERKRQEELRRQQEEILR 764 Query: 2455 KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERER 2514 + + E ++ + + RKQ EEA QR+ + RR R++ ER++ Sbjct: 765 RQQEEERKRREEEELAR---RKQ---------EEALRR---QREQEIALRRQREEEERQQ 809 Query: 2515 LEKERTEKERLEREKAERERLEKL--RALEERSDWEGEGEEDHEGKKEKDL 2563 E+ E RE+ ER + E+L + EE + W E EE +E L Sbjct: 810 QEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 860 Score = 36.6 bits (83), Expect = 0.66 Identities = 47/276 (17%), Positives = 108/276 (39%), Gaps = 17/276 (6%) Query: 2267 QDYAAMKAQEKAKKEQEERKHKGALEKEKER-----LQNMDEEEYDALTEEEKLTFDRGI 2321 Q A + E K E+E + ++ ++R LQ +++ L+ ++ G Sbjct: 933 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 992 Query: 2322 QQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQ--GPIKEEPPMKKS 2379 ++L E ++ E ++ K+ Q+++ Q+ R + G G I PP + Sbjct: 993 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPP---N 1049 Query: 2380 QAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQED 2439 Q A+ V + +T + + + E N +N + S+ V ++++ Sbjct: 1050 QWASDLVSSIWS---NADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQN 1106 Query: 2440 SEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPP----AGMEEAPHEPDD 2495 + + + K K + + + +L + + +P E+P+E D Sbjct: 1107 KKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHD 1166 Query: 2496 QRQVPLGGRRGRKDRERERLEKERTEKERLEREKAE 2531 + LG K+ ++ LE+ +K +R++ + Sbjct: 1167 YIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQ 1202 >gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens] Length = 1320 Score = 60.5 bits (145), Expect = 4e-08 Identities = 63/272 (23%), Positives = 127/272 (46%), Gaps = 36/272 (13%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332 +A+ +AK+E+EERK + L +++E + +EE EEE+L R ++ALR ++RE Sbjct: 764 EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA-RRKQEEALR--RQRE 820 Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392 QE + +E++ ERQ++E+ L+R ++ ++ EE K+ + KQ K Sbjct: 821 QEIALRRQREEE-----ERQQQEEALRRLEERRRE----EEERRKQEELLRKQEEEAAKW 871 Query: 2393 DVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQL 2452 + E +R++ E + +EE + + +++E + K+L Sbjct: 872 AREEEEAQRRL--EENRLRMEEEAARLRH-------------EEEERKRKELEVQRQKEL 916 Query: 2453 APKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRER 2512 + + + L+ +Q ++Q QL + + + E Sbjct: 917 MRQRQQQQEALRRLQ------QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 970 Query: 2513 ERLEKERTEKERLEREKAERERLEKLRALEER 2544 ++LE+ER ER RE+ R++ E ++AL+++ Sbjct: 971 QKLEEER---ERQLREEQRRQQRELMKALQQQ 999 Score = 45.8 bits (107), Expect = 0.001 Identities = 38/176 (21%), Positives = 81/176 (46%), Gaps = 14/176 (7%) Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLT 2316 RE L ++ + QE+A + EER+ + +++E L EEE EE+ Sbjct: 819 REQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEA 878 Query: 2317 FDRGIQQALRERKK------REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQG-- 2368 R + LR ++ E+ER KE++ ++ ++ + +++++ E RR+++ +Q Sbjct: 879 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQ 938 Query: 2369 ------PIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNK 2418 P + + A + L+ +++ ER+ +RE+ ++ EL K Sbjct: 939 LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMK 994 Score = 45.4 bits (106), Expect = 0.001 Identities = 48/279 (17%), Positives = 119/279 (42%), Gaps = 22/279 (7%) Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLT 2316 +E I ++ + +E A+++QEE + ++E+E EE + +EE L Sbjct: 786 QEEILRRQQEEERKRREEEELARRKQEEALRR---QREQEIALRRQREEEERQQQEEAL- 841 Query: 2317 FDRGIQQALRERKKREQERLAKEMQEKKLQQELER-QKEEDELKRRVKKGKQGPIKEEPP 2375 + L ER++ E+ER +E +K ++E + +EE+E +RR+++ + +E Sbjct: 842 ------RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 895 Query: 2376 MKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQ 2435 ++ + K+ K ++R+ + Q ++E L + ++ + + L Sbjct: 896 LRHEEEERKR---------KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPS 946 Query: 2436 DQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD 2495 + N+ Q + ++ + L R+Q +L A ++ + Sbjct: 947 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQ--QQQQQ 1004 Query: 2496 QRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERER 2534 Q+ G + LE ++ E ++++++ ++++ Sbjct: 1005 QKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1043 Score = 38.9 bits (89), Expect = 0.13 Identities = 64/291 (21%), Positives = 124/291 (42%), Gaps = 39/291 (13%) Query: 2287 HKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGI-----QQALRERKK-----REQERL 2336 H G L++E+ Q +E AL + + L + + + Q L +++K ++Q++L Sbjct: 622 HMGELDQERLTRQ----QELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQL 677 Query: 2337 AKEMQE-KKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV-DV 2394 A +Q+ + L+ + Q + R V G I E P A+ V V D+ Sbjct: 678 ALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPT----ASQPTVWEGGSVWDL 733 Query: 2395 KMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAP 2454 ++T ++ + EK + K ++ + M +++E + + +++ Sbjct: 734 PLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKR--EEEERKRQEELRRQQEEILR 791 Query: 2455 KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERER 2514 + + E ++ + + RKQ EEA QR+ + RR R++ ER++ Sbjct: 792 RQQEEERKRREEEELAR---RKQ---------EEALRR---QREQEIALRRQREEEERQQ 836 Query: 2515 LEKERTEKERLEREKAERERLEKL--RALEERSDWEGEGEEDHEGKKEKDL 2563 E+ E RE+ ER + E+L + EE + W E EE +E L Sbjct: 837 QEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 887 Score = 36.6 bits (83), Expect = 0.66 Identities = 47/276 (17%), Positives = 108/276 (39%), Gaps = 17/276 (6%) Query: 2267 QDYAAMKAQEKAKKEQEERKHKGALEKEKER-----LQNMDEEEYDALTEEEKLTFDRGI 2321 Q A + E K E+E + ++ ++R LQ +++ L+ ++ G Sbjct: 960 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 1019 Query: 2322 QQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQ--GPIKEEPPMKKS 2379 ++L E ++ E ++ K+ Q+++ Q+ R + G G I PP + Sbjct: 1020 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPP---N 1076 Query: 2380 QAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQED 2439 Q A+ V + +T + + + E N +N + S+ V ++++ Sbjct: 1077 QWASDLVSSIWS---NADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQN 1133 Query: 2440 SEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPP----AGMEEAPHEPDD 2495 + + + K K + + + +L + + +P E+P+E D Sbjct: 1134 KKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHD 1193 Query: 2496 QRQVPLGGRRGRKDRERERLEKERTEKERLEREKAE 2531 + LG K+ ++ LE+ +K +R++ + Sbjct: 1194 YIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQ 1229 >gi|156766043 GRB10 interacting GYF protein 2 isoform b [Homo sapiens] Length = 1299 Score = 60.5 bits (145), Expect = 4e-08 Identities = 63/272 (23%), Positives = 127/272 (46%), Gaps = 36/272 (13%) Query: 2273 KAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGIQQALRERKKRE 2332 +A+ +AK+E+EERK + L +++E + +EE EEE+L R ++ALR ++RE Sbjct: 743 EAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA-RRKQEEALR--RQRE 799 Query: 2333 QERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV 2392 QE + +E++ ERQ++E+ L+R ++ ++ EE K+ + KQ K Sbjct: 800 QEIALRRQREEE-----ERQQQEEALRRLEERRRE----EEERRKQEELLRKQEEEAAKW 850 Query: 2393 DVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQL 2452 + E +R++ E + +EE + + +++E + K+L Sbjct: 851 AREEEEAQRRL--EENRLRMEEEAARLRH-------------EEEERKRKELEVQRQKEL 895 Query: 2453 APKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRER 2512 + + + L+ +Q ++Q QL + + + E Sbjct: 896 MRQRQQQQEALRRLQ------QQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEI 949 Query: 2513 ERLEKERTEKERLEREKAERERLEKLRALEER 2544 ++LE+ER ER RE+ R++ E ++AL+++ Sbjct: 950 QKLEEER---ERQLREEQRRQQRELMKALQQQ 978 Score = 45.8 bits (107), Expect = 0.001 Identities = 38/176 (21%), Positives = 81/176 (46%), Gaps = 14/176 (7%) Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLT 2316 RE L ++ + QE+A + EER+ + +++E L EEE EE+ Sbjct: 798 REQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEA 857 Query: 2317 FDRGIQQALRERKK------REQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQG-- 2368 R + LR ++ E+ER KE++ ++ ++ + +++++ E RR+++ +Q Sbjct: 858 QRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQ 917 Query: 2369 ------PIKEEPPMKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNK 2418 P + + A + L+ +++ ER+ +RE+ ++ EL K Sbjct: 918 LAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMK 973 Score = 45.4 bits (106), Expect = 0.001 Identities = 48/279 (17%), Positives = 119/279 (42%), Gaps = 22/279 (7%) Query: 2257 REHIYILNMAQDYAAMKAQEKAKKEQEERKHKGALEKEKERLQNMDEEEYDALTEEEKLT 2316 +E I ++ + +E A+++QEE + ++E+E EE + +EE L Sbjct: 765 QEEILRRQQEEERKRREEEELARRKQEEALRR---QREQEIALRRQREEEERQQQEEAL- 820 Query: 2317 FDRGIQQALRERKKREQERLAKEMQEKKLQQELER-QKEEDELKRRVKKGKQGPIKEEPP 2375 + L ER++ E+ER +E +K ++E + +EE+E +RR+++ + +E Sbjct: 821 ------RRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAAR 874 Query: 2376 MKKSQAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQ 2435 ++ + K+ K ++R+ + Q ++E L + ++ + + L Sbjct: 875 LRHEEEERKR---------KELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPS 925 Query: 2436 DQEDSEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDD 2495 + N+ Q + ++ + L R+Q +L A ++ + Sbjct: 926 SSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQ--QQQQQ 983 Query: 2496 QRQVPLGGRRGRKDRERERLEKERTEKERLEREKAERER 2534 Q+ G + LE ++ E ++++++ ++++ Sbjct: 984 QKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQ 1022 Score = 38.9 bits (89), Expect = 0.13 Identities = 64/291 (21%), Positives = 124/291 (42%), Gaps = 39/291 (13%) Query: 2287 HKGALEKEKERLQNMDEEEYDALTEEEKLTFDRGI-----QQALRERKK-----REQERL 2336 H G L++E+ Q +E AL + + L + + + Q L +++K ++Q++L Sbjct: 601 HMGELDQERLTRQ----QELTALYQMQHLQYQQFLIQQQYAQVLAQQQKAALSSQQQQQL 656 Query: 2337 AKEMQE-KKLQQELERQKEEDELKRRVKKGKQGPIKEEPPMKKSQAANKQVPPLTKV-DV 2394 A +Q+ + L+ + Q + R V G I E P A+ V V D+ Sbjct: 657 ALLLQQFQTLKMRISDQNIIPSVTRSVSVPDTGSIWELQPT----ASQPTVWEGGSVWDL 712 Query: 2395 KMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQEDSEGDNSKDPDKQLAP 2454 ++T ++ + EK + K ++ + M +++E + + +++ Sbjct: 713 PLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKR--EEEERKRQEELRRQQEEILR 770 Query: 2455 KFKTYELTLKDVQNILMYWDRKQGVQLPPAGMEEAPHEPDDQRQVPLGGRRGRKDRERER 2514 + + E ++ + + RKQ EEA QR+ + RR R++ ER++ Sbjct: 771 RQQEEERKRREEEELAR---RKQ---------EEALRR---QREQEIALRRQREEEERQQ 815 Query: 2515 LEKERTEKERLEREKAERERLEKL--RALEERSDWEGEGEEDHEGKKEKDL 2563 E+ E RE+ ER + E+L + EE + W E EE +E L Sbjct: 816 QEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRL 866 Score = 36.6 bits (83), Expect = 0.66 Identities = 47/276 (17%), Positives = 108/276 (39%), Gaps = 17/276 (6%) Query: 2267 QDYAAMKAQEKAKKEQEERKHKGALEKEKER-----LQNMDEEEYDALTEEEKLTFDRGI 2321 Q A + E K E+E + ++ ++R LQ +++ L+ ++ G Sbjct: 939 QSQATLSLAEIQKLEEERERQLREEQRRQQRELMKALQQQQQQQQQKLSGWGNVSKPSGT 998 Query: 2322 QQALRERKKREQERLAKEMQEKKLQQELERQKEEDELKRRVKKGKQ--GPIKEEPPMKKS 2379 ++L E ++ E ++ K+ Q+++ Q+ R + G G I PP + Sbjct: 999 TKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGNSVWGSINTGPP---N 1055 Query: 2380 QAANKQVPPLTKVDVKMETIERKISVREQTMSEKEELNKKKRNMGDVSMHGLPLVQDQED 2439 Q A+ V + +T + + + E N +N + S+ V ++++ Sbjct: 1056 QWASDLVSSIWS---NADTKNSNMGFWDDAVKEVGPRNSTNKNKNNASLSKSVGVSNRQN 1112 Query: 2440 SEGDNSKDPDKQLAPKFKTYELTLKDVQNILMYWDRKQGVQLPP----AGMEEAPHEPDD 2495 + + + K K + + + +L + + +P E+P+E D Sbjct: 1113 KKVEEEEKLLKLFQGVNKAQDGFTQWCEQMLHALNTANNLDVPTFVSFLKEVESPYEVHD 1172 Query: 2496 QRQVPLGGRRGRKDRERERLEKERTEKERLEREKAE 2531 + LG K+ ++ LE+ +K +R++ + Sbjct: 1173 YIRAYLGDTSEAKEFAKQFLERRAKQKANQQRQQQQ 1208 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.135 0.398 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 202,986,823 Number of Sequences: 37866 Number of extensions: 9893038 Number of successful extensions: 58079 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 270 Number of HSP's successfully gapped in prelim test: 931 Number of HSP's that attempted gapping in prelim test: 32972 Number of HSP's gapped (non-prelim): 12719 length of query: 5120 length of database: 18,247,518 effective HSP length: 124 effective length of query: 4996 effective length of database: 13,552,134 effective search space: 67706461464 effective search space used: 67706461464 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 73 (32.7 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.