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Search of human proteins with 239752518
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239752518 PREDICTED: similar to leucine rich repeat
containing 50, partial [Homo sapiens]
(489 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239752518 PREDICTED: similar to leucine rich repeat containin... 965 0.0
gi|55743114 leucine rich repeat containing 49 [Homo sapiens] 929 0.0
gi|206725447 leucine rich repeat containing 23 isoform a [Homo s... 77 4e-14
gi|42542396 leucine rich repeat containing 23 isoform a [Homo sa... 77 4e-14
gi|31621309 leucine rich repeat containing 6 [Homo sapiens] 75 1e-13
gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo sap... 71 2e-12
gi|117414162 sodium channel associated protein 2 isoform a [Homo... 69 7e-12
gi|194272228 leucine rich repeat containing 48 isoform b [Homo s... 67 3e-11
gi|194272226 leucine rich repeat containing 48 isoform b [Homo s... 67 3e-11
gi|194272224 leucine rich repeat containing 48 isoform a [Homo s... 67 3e-11
gi|194272222 leucine rich repeat containing 48 isoform a [Homo s... 67 3e-11
gi|157674358 leucine rich repeat containing 50 [Homo sapiens] 67 3e-11
gi|21389483 leucine-rich repeats and guanylate kinase domain con... 67 3e-11
gi|164607156 axonemal dynein light chain 1 [Homo sapiens] 64 2e-10
gi|87298937 centrosomal protein 110kDa [Homo sapiens] 59 8e-09
gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo... 55 1e-07
gi|239754500 PREDICTED: Leucine-rich repeat-containing protein E... 54 3e-07
gi|239749060 PREDICTED: Leucine-rich repeat-containing protein E... 54 3e-07
gi|239743086 PREDICTED: Leucine-rich repeat-containing protein E... 54 3e-07
gi|239508737 PREDICTED: Leucine-rich repeat-containing protein E... 54 3e-07
gi|15529980 leucine rich repeat containing 46 [Homo sapiens] 54 4e-07
gi|66472382 nischarin [Homo sapiens] 53 7e-07
gi|41281398 soc-2 suppressor of clear homolog [Homo sapiens] 53 7e-07
gi|31377705 centrosomal protein 97kDa [Homo sapiens] 52 9e-07
gi|157785649 leucine-rich repeats and IQ motif containing 3 [Hom... 52 2e-06
gi|21687175 leucine rich transmembrane and 0-methyltransferase d... 51 2e-06
gi|62899065 centrosomal protein 72 kDa [Homo sapiens] 48 2e-05
gi|54607118 leucine-rich repeats and immunoglobulin-like domains... 48 2e-05
gi|51317373 netrin-G1 ligand [Homo sapiens] 47 5e-05
gi|4758460 glycoprotein V (platelet) [Homo sapiens] 46 7e-05
>gi|239752518 PREDICTED: similar to leucine rich repeat containing
50, partial [Homo sapiens]
Length = 489
Score = 965 bits (2495), Expect = 0.0
Identities = 489/489 (100%), Positives = 489/489 (100%)
Query: 1 MSSNLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQIT 60
MSSNLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQIT
Sbjct: 1 MSSNLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQIT 60
Query: 61 FVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNM 120
FVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNM
Sbjct: 61 FVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNM 120
Query: 121 MQLRQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQQRV 180
MQLRQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQQRV
Sbjct: 121 MQLRQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQQRV 180
Query: 181 ANIATNEDRKDSDSPQDPCQIDGSTLSAFPEETGPLDSGLNNALQGLSVIDTYLVEVDGD 240
ANIATNEDRKDSDSPQDPCQIDGSTLSAFPEETGPLDSGLNNALQGLSVIDTYLVEVDGD
Sbjct: 181 ANIATNEDRKDSDSPQDPCQIDGSTLSAFPEETGPLDSGLNNALQGLSVIDTYLVEVDGD 240
Query: 241 TLSLYGSGALESLDRNWSVQTAGMITTVSFTFIEFDEIVQVLPKLKIKFPNSLHLKFKET 300
TLSLYGSGALESLDRNWSVQTAGMITTVSFTFIEFDEIVQVLPKLKIKFPNSLHLKFKET
Sbjct: 241 TLSLYGSGALESLDRNWSVQTAGMITTVSFTFIEFDEIVQVLPKLKIKFPNSLHLKFKET 300
Query: 301 NLVMLQQFNALAQLRRIDQLTIDPQGNPVVNFTLWKYYVLFRLSHFSMQKINGTEVTQND 360
NLVMLQQFNALAQLRRIDQLTIDPQGNPVVNFTLWKYYVLFRLSHFSMQKINGTEVTQND
Sbjct: 301 NLVMLQQFNALAQLRRIDQLTIDPQGNPVVNFTLWKYYVLFRLSHFSMQKINGTEVTQND 360
Query: 361 MIMAERLFGILAHVASSELPQYRLISILGDARKKQFRYLLESKGKKPGIINEENNDSKRL 420
MIMAERLFGILAHVASSELPQYRLISILGDARKKQFRYLLESKGKKPGIINEENNDSKRL
Sbjct: 361 MIMAERLFGILAHVASSELPQYRLISILGDARKKQFRYLLESKGKKPGIINEENNDSKRL 420
Query: 421 VGENTNRATLNYTTRDFYNEKLEEIKEKKKFCKTYIEDLVKEATEINMKNEALQKLGTRL 480
VGENTNRATLNYTTRDFYNEKLEEIKEKKKFCKTYIEDLVKEATEINMKNEALQKLGTRL
Sbjct: 421 VGENTNRATLNYTTRDFYNEKLEEIKEKKKFCKTYIEDLVKEATEINMKNEALQKLGTRL 480
Query: 481 EEFAAEVAG 489
EEFAAEVAG
Sbjct: 481 EEFAAEVAG 489
>gi|55743114 leucine rich repeat containing 49 [Homo sapiens]
Length = 686
Score = 929 bits (2402), Expect = 0.0
Identities = 472/474 (99%), Positives = 473/474 (99%), Gaps = 1/474 (0%)
Query: 4 NLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVR 63
+LDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVR
Sbjct: 179 SLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVR 238
Query: 64 DVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQL 123
DVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQL
Sbjct: 239 DVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQL 298
Query: 124 RQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQQ-RVAN 182
RQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQQ RVAN
Sbjct: 299 RQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQQQRVAN 358
Query: 183 IATNEDRKDSDSPQDPCQIDGSTLSAFPEETGPLDSGLNNALQGLSVIDTYLVEVDGDTL 242
IATNEDRKDSDSPQDPCQIDGSTLSAFPEETGPLDSGLNNALQGLSVIDTYLVEVDGDTL
Sbjct: 359 IATNEDRKDSDSPQDPCQIDGSTLSAFPEETGPLDSGLNNALQGLSVIDTYLVEVDGDTL 418
Query: 243 SLYGSGALESLDRNWSVQTAGMITTVSFTFIEFDEIVQVLPKLKIKFPNSLHLKFKETNL 302
SLYGSGALESLDRNWSVQTAGMITTVSFTFIEFDEIVQVLPKLKIKFPNSLHLKFKETNL
Sbjct: 419 SLYGSGALESLDRNWSVQTAGMITTVSFTFIEFDEIVQVLPKLKIKFPNSLHLKFKETNL 478
Query: 303 VMLQQFNALAQLRRIDQLTIDPQGNPVVNFTLWKYYVLFRLSHFSMQKINGTEVTQNDMI 362
VMLQQFNALAQLRRIDQLTIDPQGNPVVNFTLWKYYVLFRLSHFSMQKINGTEVTQNDMI
Sbjct: 479 VMLQQFNALAQLRRIDQLTIDPQGNPVVNFTLWKYYVLFRLSHFSMQKINGTEVTQNDMI 538
Query: 363 MAERLFGILAHVASSELPQYRLISILGDARKKQFRYLLESKGKKPGIINEENNDSKRLVG 422
MAERLFGILAHVASSELPQYRLISILGDARKKQFRYLLESKGKKPGIINEENNDSKRLVG
Sbjct: 539 MAERLFGILAHVASSELPQYRLISILGDARKKQFRYLLESKGKKPGIINEENNDSKRLVG 598
Query: 423 ENTNRATLNYTTRDFYNEKLEEIKEKKKFCKTYIEDLVKEATEINMKNEALQKL 476
ENTNRATLNYTTRDFYNEKLEEIKEKKKFCKTYIEDLVKEATEINMKNEALQKL
Sbjct: 599 ENTNRATLNYTTRDFYNEKLEEIKEKKKFCKTYIEDLVKEATEINMKNEALQKL 652
Score = 54.7 bits (130), Expect = 2e-07
Identities = 39/125 (31%), Positives = 60/125 (48%), Gaps = 8/125 (6%)
Query: 6 DVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDV 65
D L L ++T IN LR+LN NF++ + N++ L L L+L NQI + +
Sbjct: 93 DRLSLERQKLTVCPIINGEDHLRLLNFQHNFITRIQNISNLQKLISLDLYDNQIEEISGL 152
Query: 66 DNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQ 125
L CL+ L L N I +S L + SL + GN I K + ++ +LR
Sbjct: 153 STLRCLRVLLLGKNRIK---KISNLENLKSLDVLDLHGNQIT-----KIENINHLCELRV 204
Query: 126 LDMKR 130
L++ R
Sbjct: 205 LNLAR 209
>gi|206725447 leucine rich repeat containing 23 isoform a [Homo
sapiens]
Length = 343
Score = 77.0 bits (188), Expect = 4e-14
Identities = 55/164 (33%), Positives = 87/164 (53%), Gaps = 3/164 (1%)
Query: 4 NLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVR 63
+L ++L GNQ+ IN L +L+ L LA+N L V+ L L +LT L+LR NQI +
Sbjct: 180 SLHTVELRGNQLESTLGIN-LPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLS 238
Query: 64 DVDN-LPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQ 122
+ LQ+L L N +++ ++ L D L + NP E+ Y+ L M
Sbjct: 239 GFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPY 298
Query: 123 LRQLDMKRITEEERRMASVLAKK-EEEKKRESHKQSLLKEKKRL 165
L +LD + EEER A V+ ++ +EEK++E Q L+ ++ L
Sbjct: 299 LERLDKEFYEEEERAEADVIRQRLKEEKEQEPEPQRDLEPEQSL 342
>gi|42542396 leucine rich repeat containing 23 isoform a [Homo
sapiens]
Length = 343
Score = 77.0 bits (188), Expect = 4e-14
Identities = 55/164 (33%), Positives = 87/164 (53%), Gaps = 3/164 (1%)
Query: 4 NLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVR 63
+L ++L GNQ+ IN L +L+ L LA+N L V+ L L +LT L+LR NQI +
Sbjct: 180 SLHTVELRGNQLESTLGIN-LPKLKNLYLAQNMLKKVEGLEDLSNLTTLHLRDNQIDTLS 238
Query: 64 DVDN-LPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQ 122
+ LQ+L L N +++ ++ L D L + NP E+ Y+ L M
Sbjct: 239 GFSREMKSLQYLNLRGNMVANLGELAKLRDLPKLRALVLLDNPCTDETSYRQEALVQMPY 298
Query: 123 LRQLDMKRITEEERRMASVLAKK-EEEKKRESHKQSLLKEKKRL 165
L +LD + EEER A V+ ++ +EEK++E Q L+ ++ L
Sbjct: 299 LERLDKEFYEEEERAEADVIRQRLKEEKEQEPEPQRDLEPEQSL 342
>gi|31621309 leucine rich repeat containing 6 [Homo sapiens]
Length = 466
Score = 75.1 bits (183), Expect = 1e-13
Identities = 50/161 (31%), Positives = 79/161 (49%), Gaps = 1/161 (0%)
Query: 4 NLDVLDLHGNQITKIENINHLC-ELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFV 62
+L+ L LH +I ++E+I+ C +L++L L N + ++N++ L L LNL N I +
Sbjct: 22 SLEELSLHQQEIERLEHIDKWCRDLKILYLQNNLIGKIENVSKLKKLEYLNLALNNIEKI 81
Query: 63 RDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQ 122
+++ L L L+ N I S+ L + L ++ GNP A Y+ V+ + Q
Sbjct: 82 ENLEGCEELAKLDLTVNFIGELSSIKNLQHNIHLKELFLMGNPCASFDHYREFVVATLPQ 141
Query: 123 LRQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKK 163
L+ LD K I ER A E + RE K LK K
Sbjct: 142 LKWLDGKEIEPSERIKALQDYSVIEPQIREQEKDHCLKRAK 182
>gi|4506013 protein phosphatase 1, regulatory subunit 7 [Homo
sapiens]
Length = 360
Score = 71.2 bits (173), Expect = 2e-12
Identities = 36/125 (28%), Positives = 71/125 (56%)
Query: 3 SNLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFV 62
+NL VL + N++TKIE + +L LR L L+ N + ++ L + LT L++ N+I +
Sbjct: 230 TNLTVLSMQSNRLTKIEGLQNLVNLRELYLSHNGIEVIEGLENNNKLTMLDIASNRIKKI 289
Query: 63 RDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQ 122
++ +L LQ +++ N + S+ + L + SL + + NP+ ++ Y+ V+ +
Sbjct: 290 ENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRKVMLALPS 349
Query: 123 LRQLD 127
+RQ+D
Sbjct: 350 VRQID 354
Score = 62.0 bits (149), Expect = 1e-09
Identities = 34/93 (36%), Positives = 58/93 (62%)
Query: 4 NLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVR 63
+L LDL+ NQI KIEN+ L EL +L+++ N L +++ ++ L L +L L +N+I+ +
Sbjct: 121 SLRELDLYDNQIKKIENLEALTELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIE 180
Query: 64 DVDNLPCLQHLFLSFNNISSFDSVSCLADSSSL 96
++ NL LQ L L N I + +++ L + SL
Sbjct: 181 NLSNLHQLQMLELGSNRIRAIENIDTLTNLESL 213
Score = 61.6 bits (148), Expect = 2e-09
Identities = 38/124 (30%), Positives = 67/124 (54%), Gaps = 8/124 (6%)
Query: 3 SNLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFV 62
+ L++LD+ N + IE ++ L L+ L L N +S ++NL+ L L L L N+I +
Sbjct: 142 TELEILDISFNLLRNIEGVDKLTRLKKLFLVNNKISKIENLSNLHQLQMLELGSNRIRAI 201
Query: 63 RDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQ 122
++D L L+ LFL N I+ ++ L ++L+ ++ N + K LQN++
Sbjct: 202 ENIDTLTNLESLFLGKNKITKLQNLDAL---TNLTVLSMQSNRLT-----KIEGLQNLVN 253
Query: 123 LRQL 126
LR+L
Sbjct: 254 LREL 257
Score = 61.2 bits (147), Expect = 2e-09
Identities = 44/158 (27%), Positives = 79/158 (50%), Gaps = 14/158 (8%)
Query: 5 LDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRD 64
L +L+L N+I IENI+ L L L L +N ++ + NL+ L +LT L+++ N++T +
Sbjct: 188 LQMLELGSNRIRAIENIDTLTNLESLFLGKNKITKLQNLDALTNLTVLSMQSNRLTKIEG 247
Query: 65 VDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPI-----------AQESWYK 113
+ NL L+ L+LS N I + + L +++ L+ + N I QE W
Sbjct: 248 LQNLVNLRELYLSHNGI---EVIEGLENNNKLTMLDIASNRIKKIENISHLTELQEFWMN 304
Query: 114 HTVLQNMMQLRQLDMKRITEEERRMASVLAKKEEEKKR 151
+L++ L +L R E + L K + +++
Sbjct: 305 DNLLESWSDLDELKGARSLETVYLERNPLQKDPQYRRK 342
Score = 51.6 bits (122), Expect = 2e-06
Identities = 37/121 (30%), Positives = 64/121 (52%), Gaps = 11/121 (9%)
Query: 8 LDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDVDN 67
+DL+ +I KIE L +++ L L +N + ++NL L SL EL+L NQI + +++
Sbjct: 81 VDLNHYRIGKIEGFEVLKKVKTLCLRQNLIKCIENLEELQSLRELDLYDNQIKKIENLEA 140
Query: 68 LPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLD 127
L L+ L +SFN + + + V L + L + N I++ ++N+ L QL
Sbjct: 141 LTELEILDISFNLLRNIEGVDKL---TRLKKLFLVNNKISK--------IENLSNLHQLQ 189
Query: 128 M 128
M
Sbjct: 190 M 190
Score = 40.4 bits (93), Expect = 0.004
Identities = 24/61 (39%), Positives = 35/61 (57%), Gaps = 3/61 (4%)
Query: 2 SSNLDVLDLHGNQITKIENINHLCELRVLNLARNFL---SHVDNLNGLDSLTELNLRHNQ 58
++ L +LD+ N+I KIENI+HL EL+ + N L S +D L G SL + L N
Sbjct: 273 NNKLTMLDIASNRIKKIENISHLTELQEFWMNDNLLESWSDLDELKGARSLETVYLERNP 332
Query: 59 I 59
+
Sbjct: 333 L 333
>gi|117414162 sodium channel associated protein 2 isoform a [Homo
sapiens]
Length = 1032
Score = 69.3 bits (168), Expect = 7e-12
Identities = 51/172 (29%), Positives = 81/172 (47%), Gaps = 31/172 (18%)
Query: 1 MSSNLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQIT 60
+ S L ++LH N I+KIE I+H+ L+ L+L+ N +S ++ LN L L LNL N IT
Sbjct: 41 LDSTLHAVNLHCNNISKIEAIDHIWNLQHLDLSSNQISRIEGLNTLTKLCTLNLSCNLIT 100
Query: 61 FVRDVDNLPCLQHLFLSFNNI-----------------------SSFDSV----SCLADS 93
V ++ L L L +S+N+I + DS+ C+
Sbjct: 101 KVEGLEELINLTRLNVSYNHIDDLSGLIPLHGIKHKLRYIDLHSNRIDSIHHLLQCMVGL 160
Query: 94 SSLSDITF----DGNPIAQESWYKHTVLQNMMQLRQLDMKRITEEERRMASV 141
L+++ D NP+ + Y+ +LQ + QLR LD K I E + +
Sbjct: 161 HFLTNLILEKDGDDNPVCRLPGYRAVILQTLPQLRILDCKNIFGEPVNLTEI 212
Score = 32.7 bits (73), Expect = 0.77
Identities = 21/62 (33%), Positives = 33/62 (53%), Gaps = 9/62 (14%)
Query: 45 GLDSLTEL---------NLRHNQITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSS 95
GL S++EL NL N I+ + +D++ LQHL LS N IS + ++ L +
Sbjct: 32 GLQSISELSLDSTLHAVNLHCNNISKIEAIDHIWNLQHLDLSSNQISRIEGLNTLTKLCT 91
Query: 96 LS 97
L+
Sbjct: 92 LN 93
>gi|194272228 leucine rich repeat containing 48 isoform b [Homo
sapiens]
Length = 457
Score = 67.4 bits (163), Expect = 3e-11
Identities = 46/157 (29%), Positives = 82/157 (52%), Gaps = 2/157 (1%)
Query: 4 NLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVR 63
NL L L N I KIE + +L L L+L+ N + ++ L+ L +L +L+L +N+I+ +
Sbjct: 66 NLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKID 125
Query: 64 DVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQL 123
+D L LQ L L N I + ++ L L ++ NPI++ YK + + L
Sbjct: 126 SLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDL 185
Query: 124 RQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLK 160
LD +RI + +++A AK + H+++L++
Sbjct: 186 MYLDYRRIDDHTKKLAE--AKHQYSIDELKHQENLMQ 220
>gi|194272226 leucine rich repeat containing 48 isoform b [Homo
sapiens]
Length = 457
Score = 67.4 bits (163), Expect = 3e-11
Identities = 46/157 (29%), Positives = 82/157 (52%), Gaps = 2/157 (1%)
Query: 4 NLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVR 63
NL L L N I KIE + +L L L+L+ N + ++ L+ L +L +L+L +N+I+ +
Sbjct: 66 NLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKID 125
Query: 64 DVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQL 123
+D L LQ L L N I + ++ L L ++ NPI++ YK + + L
Sbjct: 126 SLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDL 185
Query: 124 RQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLK 160
LD +RI + +++A AK + H+++L++
Sbjct: 186 MYLDYRRIDDHTKKLAE--AKHQYSIDELKHQENLMQ 220
>gi|194272224 leucine rich repeat containing 48 isoform a [Homo
sapiens]
Length = 523
Score = 67.4 bits (163), Expect = 3e-11
Identities = 46/157 (29%), Positives = 82/157 (52%), Gaps = 2/157 (1%)
Query: 4 NLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVR 63
NL L L N I KIE + +L L L+L+ N + ++ L+ L +L +L+L +N+I+ +
Sbjct: 66 NLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKID 125
Query: 64 DVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQL 123
+D L LQ L L N I + ++ L L ++ NPI++ YK + + L
Sbjct: 126 SLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDL 185
Query: 124 RQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLK 160
LD +RI + +++A AK + H+++L++
Sbjct: 186 MYLDYRRIDDHTKKLAE--AKHQYSIDELKHQENLMQ 220
>gi|194272222 leucine rich repeat containing 48 isoform a [Homo
sapiens]
Length = 523
Score = 67.4 bits (163), Expect = 3e-11
Identities = 46/157 (29%), Positives = 82/157 (52%), Gaps = 2/157 (1%)
Query: 4 NLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVR 63
NL L L N I KIE + +L L L+L+ N + ++ L+ L +L +L+L +N+I+ +
Sbjct: 66 NLRKLQLDNNIIEKIEGLENLAHLVWLDLSFNNIETIEGLDTLVNLEDLSLFNNRISKID 125
Query: 64 DVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQL 123
+D L LQ L L N I + ++ L L ++ NPI++ YK + + L
Sbjct: 126 SLDALVKLQVLSLGNNRIDNMMNIIYLRRFKCLRTLSLSRNPISEAEDYKMFICAYLPDL 185
Query: 124 RQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLK 160
LD +RI + +++A AK + H+++L++
Sbjct: 186 MYLDYRRIDDHTKKLAE--AKHQYSIDELKHQENLMQ 220
>gi|157674358 leucine rich repeat containing 50 [Homo sapiens]
Length = 725
Score = 67.4 bits (163), Expect = 3e-11
Identities = 57/193 (29%), Positives = 85/193 (44%), Gaps = 32/193 (16%)
Query: 3 SNLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFV 62
+ L L L N I KIEN+ ELR L L N L ++NL L L LNL +N ++
Sbjct: 129 TGLRCLWLQSNGIQKIENLEAQTELRCLFLQMNLLRKIENLEPLQKLDALNLSNN---YI 185
Query: 63 RDVDNLPCL-------------------QH---------LFLSFNNISSFDSVSCLADSS 94
+ ++NL CL QH L LS N +S + +S L
Sbjct: 186 KTIENLSCLPVLNTLQMAHNHLETVEDIQHLQECLRLCVLDLSHNKLSDPEILSILESMP 245
Query: 95 SLSDITFDGNP-IAQESWYKHTVLQNMMQLRQLDMKRITEEERRMASVLAKKEEEKKRES 153
L + GNP I Q Y+ TV + L LD + + ++R A A+ ++E
Sbjct: 246 DLRVLNLMGNPVIRQIPNYRRTVTVRLKHLTYLDDRPVFPKDRACAEAWARGGYAAEKEE 305
Query: 154 HKQSLLKEKKRLT 166
+Q +E+K++T
Sbjct: 306 RQQWESRERKKIT 318
>gi|21389483 leucine-rich repeats and guanylate kinase domain
containing [Homo sapiens]
Length = 825
Score = 67.4 bits (163), Expect = 3e-11
Identities = 42/136 (30%), Positives = 74/136 (54%), Gaps = 1/136 (0%)
Query: 1 MSSNLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQIT 60
M +NL L L N+IT I +N L +++L L+ N + + L L +L L+L HNQI+
Sbjct: 235 MCNNLIHLSLANNKITTINGLNKL-PIKILCLSNNQIEMITGLEDLKALQNLDLSHNQIS 293
Query: 61 FVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNM 120
++ ++N L+ + L N I+ + + + L + NPI ++S Y V+ +
Sbjct: 294 SLQGLENHDLLEVINLEDNKIAELREIEYIKNLPILRVLNLLENPIQEKSEYWFFVIFML 353
Query: 121 MQLRQLDMKRITEEER 136
++L +LD K+I EE+
Sbjct: 354 LRLTELDQKKIKVEEK 369
Score = 36.6 bits (83), Expect = 0.053
Identities = 28/103 (27%), Positives = 49/103 (47%), Gaps = 3/103 (2%)
Query: 4 NLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVR 63
+L LDL N+I + ++ + L LN ++N L+ N +L + + HNQI+ +
Sbjct: 150 HLQKLDLSANKIEDLSCVSCMPYLLELNASQNNLTTFFNFKPPKNLKKADFSHNQISEIC 209
Query: 64 DVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPI 106
D+ L L L N I + +S L ++L ++ N I
Sbjct: 210 DLSAYHALTKLILDGNEI---EEISGLEMCNNLIHLSLANNKI 249
>gi|164607156 axonemal dynein light chain 1 [Homo sapiens]
Length = 190
Score = 64.3 bits (155), Expect = 2e-10
Identities = 48/153 (31%), Positives = 82/153 (53%), Gaps = 14/153 (9%)
Query: 1 MSSNLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGL----DSLTELNLRH 56
M +N + L L N I KI N+N L LR+L+L RN ++ NLNGL D+L EL + +
Sbjct: 46 MLANCEKLSLSTNCIEKIANLNGLKNLRILSLGRN---NIKNLNGLEAVGDTLEELWISY 102
Query: 57 NQITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTV 116
N I ++ + + L+ L++S N + + LA+ L D+ F GNP+ + KH+
Sbjct: 103 NFIEKLKGIHIMKKLKILYMSNNLVKDWAEFVKLAELPCLEDLVFVGNPLEE----KHSA 158
Query: 117 LQNMMQLRQLDMKRITEEERRMASVLAKKEEEK 149
N ++ KR+ + ++ + + K +EE+
Sbjct: 159 ENNWIEEA---TKRVPKLKKLDGTPVIKGDEEE 188
>gi|87298937 centrosomal protein 110kDa [Homo sapiens]
Length = 2325
Score = 59.3 bits (142), Expect = 8e-09
Identities = 47/188 (25%), Positives = 81/188 (43%), Gaps = 24/188 (12%)
Query: 2 SSNLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITF 61
S NL + G + IEN+ +L VLNL+ N + ++ L+ L L ELNL +N+I+
Sbjct: 102 SLNLSLSKDGGKKFKYIENLEKCVKLEVLNLSYNLIGKIEKLDKLLKLRELNLSYNKISK 161
Query: 62 VRDVDNLPCLQHLFLS------------------------FNNISSFDSVSCLADSSSLS 97
+ ++N+ LQ L L+ N ISS +S L L
Sbjct: 162 IEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSLQDISKLKPLQDLI 221
Query: 98 DITFDGNPIAQESWYKHTVLQNMMQLRQLDMKRITEEERRMASVLAKKEEEKKRESHKQS 157
+ NP+ Y + ++ L L+ + +T ++R+ A EE ++ E +
Sbjct: 222 SLILVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQEAFERFSLEEVERLERDLEK 281
Query: 158 LLKEKKRL 165
+ E + L
Sbjct: 282 KMIETEEL 289
Score = 55.1 bits (131), Expect = 1e-07
Identities = 57/206 (27%), Positives = 94/206 (45%), Gaps = 32/206 (15%)
Query: 8 LDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNG--LDSLTELNLRHNQITFVRDV 65
L+L N+I+KIE I ++C L+ LNLA N + H+ G L SL LNL+ N+I+ ++D+
Sbjct: 152 LNLSYNKISKIEGIENMCNLQKLNLAGNEIEHIPVWLGKKLKSLRVLNLKGNKISSLQDI 211
Query: 66 DNLPCLQHLF---LSFNNISSFDSVSCLADSSSLSDITFDGNPIA----QESWYKHTVLQ 118
L LQ L L N + + S + +G P+ QE++ + ++ +
Sbjct: 212 SKLKPLQDLISLILVENPVVTLPHYLQFTIFHLRSLESLEGQPVTTQDRQEAFERFSLEE 271
Query: 119 NMMQLRQLDMKRITEEERRMA---------------------SVLAKK--EEEKKRESHK 155
R L+ K I EE + ++L K+ EE K + K
Sbjct: 272 VERLERDLEKKMIETEELKSKQTRFLEEIKNQDKLNKSLKEEAMLQKQSCEELKSDLNTK 331
Query: 156 QSLLKEKKRLTINNVARQWDLQQRVA 181
LLK+K +Q++L+Q +A
Sbjct: 332 NELLKQKTIELTRACQKQYELEQELA 357
>gi|50593002 small nuclear ribonucleoprotein polypeptide A' [Homo
sapiens]
Length = 255
Score = 55.5 bits (132), Expect = 1e-07
Identities = 40/140 (28%), Positives = 73/140 (52%), Gaps = 3/140 (2%)
Query: 8 LDLHGNQITKIENINH-LCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRD-V 65
LDL G +I IEN+ L + ++ + N + +D L L L + +N+I + + +
Sbjct: 24 LDLRGYKIPVIENLGATLDQFDAIDFSDNEIRKLDGFPLLRRLKTLLVNNNRICRIGEGL 83
Query: 66 DN-LPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLR 124
D LPCL L L+ N++ + LA SL+ ++ NP+ + Y+ V+ + Q+R
Sbjct: 84 DQALPCLTELILTNNSLVELGDLDPLASLKSLTYLSILRNPVTNKKHYRLYVIYKVPQVR 143
Query: 125 QLDMKRITEEERRMASVLAK 144
LD +++ +ER+ A + K
Sbjct: 144 VLDFQKVKLKERQEAEKMFK 163
>gi|239754500 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 53.9 bits (128), Expect = 3e-07
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 22/202 (10%)
Query: 8 LDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDVDN 67
L L ++T++ +++ +L+ L L N L + L LTEL L +N I + +
Sbjct: 99 LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHY 158
Query: 68 LPCLQHLFLSFNNISSFDS-VSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQL 126
LP L L L N +++ D+ V L +L ++ NP+ Q + Y+ ++ ++ + L
Sbjct: 159 LPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELL 218
Query: 127 DMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQ--------Q 178
D ++TE+ERR + +HK++ + + V WD + Q
Sbjct: 219 DRNQVTEKERRSMITIF---------NHKKAHIVQSIAFG-GKVDASWDPKSPFKQKPAQ 268
Query: 179 RVAN---IATNEDRKDSDSPQD 197
RV + A N D+ D P+D
Sbjct: 269 RVPSDFAFANNVDKTVLDDPED 290
>gi|239749060 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 53.9 bits (128), Expect = 3e-07
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 22/202 (10%)
Query: 8 LDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDVDN 67
L L ++T++ +++ +L+ L L N L + L LTEL L +N I + +
Sbjct: 99 LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHY 158
Query: 68 LPCLQHLFLSFNNISSFDS-VSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQL 126
LP L L L N +++ D+ V L +L ++ NP+ Q + Y+ ++ ++ + L
Sbjct: 159 LPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELL 218
Query: 127 DMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQ--------Q 178
D ++TE+ERR + +HK++ + + V WD + Q
Sbjct: 219 DRNQVTEKERRSMITIF---------NHKKAHIVQSIAFG-GKVDASWDPKSPFKQKPAQ 268
Query: 179 RVAN---IATNEDRKDSDSPQD 197
RV + A N D+ D P+D
Sbjct: 269 RVPSDFAFANNVDKTVLDDPED 290
>gi|239743086 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 53.9 bits (128), Expect = 3e-07
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 22/202 (10%)
Query: 8 LDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDVDN 67
L L ++T++ +++ +L+ L L N L + L LTEL L +N I + +
Sbjct: 99 LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHY 158
Query: 68 LPCLQHLFLSFNNISSFDS-VSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQL 126
LP L L L N +++ D+ V L +L ++ NP+ Q + Y+ ++ ++ + L
Sbjct: 159 LPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELL 218
Query: 127 DMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQ--------Q 178
D ++TE+ERR + +HK++ + + V WD + Q
Sbjct: 219 DRNQVTEKERRSMITIF---------NHKKAHIVQSIAFG-GKVDASWDPKSPFKQKPAQ 268
Query: 179 RVAN---IATNEDRKDSDSPQD 197
RV + A N D+ D P+D
Sbjct: 269 RVPSDFAFANNVDKTVLDDPED 290
>gi|239508737 PREDICTED: Leucine-rich repeat-containing protein
ENSP00000371558 [Homo sapiens]
Length = 336
Score = 53.9 bits (128), Expect = 3e-07
Identities = 51/202 (25%), Positives = 92/202 (45%), Gaps = 22/202 (10%)
Query: 8 LDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDVDN 67
L L ++T++ +++ +L+ L L N L + L LTEL L +N I + +
Sbjct: 99 LFLSKKELTEVIDLSRFKKLKYLWLHHNKLHGITFLTRNYCLTELYLNNNAIFEIEGLHY 158
Query: 68 LPCLQHLFLSFNNISSFDS-VSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQL 126
LP L L L N +++ D+ V L +L ++ NP+ Q + Y+ ++ ++ + L
Sbjct: 159 LPSLHILLLHHNELTNIDATVKELKGMLNLKILSLYQNPLCQYNLYRLYIIYHLPGVELL 218
Query: 127 DMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQWDLQ--------Q 178
D ++TE+ERR + +HK++ + + V WD + Q
Sbjct: 219 DRNQVTEKERRSMITIF---------NHKKAHIVQSIAFG-GKVDASWDPKSPFKQKPAQ 268
Query: 179 RVAN---IATNEDRKDSDSPQD 197
RV + A N D+ D P+D
Sbjct: 269 RVPSDFAFANNVDKTVLDDPED 290
>gi|15529980 leucine rich repeat containing 46 [Homo sapiens]
Length = 321
Score = 53.5 bits (127), Expect = 4e-07
Identities = 41/129 (31%), Positives = 61/129 (47%), Gaps = 3/129 (2%)
Query: 5 LDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRD 64
L + L IT I N+ L L L L N + ++NL + SL L+L NQI V +
Sbjct: 46 LQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVEN 105
Query: 65 VDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLR 124
+ +LPCLQ L LS N I +++ SL + GN + Y+ V + + L
Sbjct: 106 LLDLPCLQFLDLSENLI---ETLKLDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLL 162
Query: 125 QLDMKRITE 133
LD + + E
Sbjct: 163 DLDGQPVVE 171
Score = 47.4 bits (111), Expect = 3e-05
Identities = 39/109 (35%), Positives = 56/109 (51%), Gaps = 3/109 (2%)
Query: 4 NLDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVR 63
NL L L GN+I +IEN+ + LR L+LA N + V+NL L L L+L N I ++
Sbjct: 67 NLHSLYLQGNKIQQIENLACIPSLRFLSLAGNQIRQVENLLDLPCLQFLDLSENLIETLK 126
Query: 64 DVDNLP-CLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESW 111
+D P L L LS N+ ++ D L + + DG P+ E W
Sbjct: 127 -LDEFPQSLLILNLSGNSCTNQDGYRELVTEALPLLLDLDGQPVV-ERW 173
Score = 35.0 bits (79), Expect = 0.15
Identities = 24/88 (27%), Positives = 43/88 (48%), Gaps = 11/88 (12%)
Query: 46 LDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNP 105
LD L + L IT +R+++ L L L+L N I ++++C+ SL ++ GN
Sbjct: 43 LDELQTVRLDREGITTIRNLEGLQNLHSLYLQGNKIQQIENLACI---PSLRFLSLAGNQ 99
Query: 106 IAQESWYKHTVLQNMMQLRQLDMKRITE 133
I Q ++N++ L L ++E
Sbjct: 100 IRQ--------VENLLDLPCLQFLDLSE 119
>gi|66472382 nischarin [Homo sapiens]
Length = 1504
Score = 52.8 bits (125), Expect = 7e-07
Identities = 33/83 (39%), Positives = 50/83 (60%), Gaps = 4/83 (4%)
Query: 4 NLDVLDLHGNQITKIENIN-HLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHN---QI 59
NL LDL N+++ +E ++ L ++ LNLA N L + L+ L SL L+LR N Q+
Sbjct: 333 NLVHLDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLSGLHKLYSLVNLDLRDNRIEQM 392
Query: 60 TFVRDVDNLPCLQHLFLSFNNIS 82
VR + +LPCL+H+ L N +S
Sbjct: 393 EEVRSIGSLPCLEHVSLLNNPLS 415
Score = 49.3 bits (116), Expect = 8e-06
Identities = 46/169 (27%), Positives = 77/169 (45%), Gaps = 7/169 (4%)
Query: 5 LDVLDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLN-GLDSLTELNLRHNQITFVR 63
++ LDL N + ++N+ HL L L+L+ N LS ++ L+ L ++ LNL N + +
Sbjct: 312 IEFLDLSHNGLLVVDNLQHLYNLVHLDLSYNKLSSLEGLHTKLGNIKTLNLAGNLLESLS 371
Query: 64 DVDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQL 123
+ L L +L L N I + V + L ++ NP++ Y+ VL +
Sbjct: 372 GLHKLYSLVNLDLRDNRIEQMEEVRSIGSLPCLEHVSLLNNPLSIIPDYRTKVLAQFGER 431
Query: 124 RQ---LDMKRITEEERRMASVL---AKKEEEKKRESHKQSLLKEKKRLT 166
LD TE+E VL K +E K + S+ + E RL+
Sbjct: 432 ASEVCLDDTVTTEKELDTVEVLKAIQKAKEVKSKLSNPEKKGGEDSRLS 480
>gi|41281398 soc-2 suppressor of clear homolog [Homo sapiens]
Length = 582
Score = 52.8 bits (125), Expect = 7e-07
Identities = 38/131 (29%), Positives = 68/131 (51%), Gaps = 8/131 (6%)
Query: 3 SNLDVLDLHGNQITKIE-NINHLCELRVLNLARNFLSHV-DNLNGLDSLTELNLRHNQIT 60
S L +L + N+I ++ I LC L L++A N L H+ + +T L+L+HN++
Sbjct: 215 SKLSMLSIRENKIKQLPAEIGELCNLITLDVAHNQLEHLPKEIGNCTQITNLDLQHNELL 274
Query: 61 FVRD-VDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQN 119
+ D + NL L L L +N +S+ LA S+L ++ + N I S ++L +
Sbjct: 275 DLPDTIGNLSSLSRLGLRYNRLSAIP--RSLAKCSALEELNLENNNI---STLPESLLSS 329
Query: 120 MMQLRQLDMKR 130
+++L L + R
Sbjct: 330 LVKLNSLTLAR 340
Score = 43.1 bits (100), Expect = 6e-04
Identities = 32/81 (39%), Positives = 49/81 (60%), Gaps = 3/81 (3%)
Query: 4 NLDVLDLHGNQITKI-ENINHLCELRVLNLARNFLSHVDNL-NGLDSLTELNLRHNQITF 61
NL L L N +T + +++++L +LR+L+L N L + ++ LDSLT L LR N+IT
Sbjct: 147 NLMTLALSENSLTSLPDSLDNLKKLRMLDLRHNKLREIPSVVYRLDSLTTLYLRFNRITT 206
Query: 62 V-RDVDNLPCLQHLFLSFNNI 81
V +D+ NL L L + N I
Sbjct: 207 VEKDIKNLSKLSMLSIRENKI 227
Score = 32.3 bits (72), Expect = 1.0
Identities = 21/56 (37%), Positives = 30/56 (53%), Gaps = 2/56 (3%)
Query: 4 NLDVLDLHGNQITKI-ENINHLCELRVLNLARNFLSHV-DNLNGLDSLTELNLRHN 57
+L L L NQ+T + I HL L L L N L+H+ + + L++L EL L N
Sbjct: 472 DLQKLVLTNNQLTTLPRGIGHLTNLTHLGLGENLLTHLPEEIGTLENLEELYLNDN 527
>gi|31377705 centrosomal protein 97kDa [Homo sapiens]
Length = 865
Score = 52.4 bits (124), Expect = 9e-07
Identities = 35/99 (35%), Positives = 50/99 (50%), Gaps = 3/99 (3%)
Query: 8 LDLHGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDVDN 67
L + N++ ++ + L LRVLNL N + V+ L L L LNL N + + +++
Sbjct: 63 LSVANNRLVRMMGVAKLTLLRVLNLPHNSIGCVEGLKELVHLEWLNLAGNNLKAMEQINS 122
Query: 68 LPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPI 106
LQHL LS NNIS +S L SL + GN I
Sbjct: 123 CTALQHLDLSDNNISQIGDLSKLV---SLKTLLLHGNII 158
>gi|157785649 leucine-rich repeats and IQ motif containing 3 [Homo
sapiens]
Length = 624
Score = 51.6 bits (122), Expect = 2e-06
Identities = 32/128 (25%), Positives = 64/128 (50%), Gaps = 3/128 (2%)
Query: 11 HGNQITKIENINHLCELRVLNLARNFLSHVDNLNGLDSLTELNLRHNQITFVRDV---DN 67
+G + +EN+ LRV + NF++ + L L +L+L NQI + + +
Sbjct: 36 NGLHLKSMENLQSCISLRVCIFSNNFITDIHPLQSCIKLIKLDLHGNQIKSLPNTKFWNG 95
Query: 68 LPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLD 127
L L+ L+L N + ++ L+ +L +T P++ + Y+H ++ ++ L+ LD
Sbjct: 96 LKNLKLLYLHDNGFAKLKNICVLSACPTLIALTMFDCPVSLKKGYRHVLVNSIWPLKALD 155
Query: 128 MKRITEEE 135
I++EE
Sbjct: 156 HHVISDEE 163
>gi|21687175 leucine rich transmembrane and 0-methyltransferase
domain containing isoform 1 [Homo sapiens]
Length = 192
Score = 51.2 bits (121), Expect = 2e-06
Identities = 42/142 (29%), Positives = 65/142 (45%), Gaps = 8/142 (5%)
Query: 20 NINHLCELRVLN-LARNFLSHVDNLNGLDSLTELNLRHNQITFVRDV-DNLPCLQHLFLS 77
N N L +LR N +A L H +NL +D L N +T + V L L+L
Sbjct: 57 NNNVLNDLRDFNQVASQLLEHPENLAWID------LSFNDLTSIDPVLTTFFNLSVLYLH 110
Query: 78 FNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTVLQNMMQLRQLDMKRITEEERR 137
N+I V+ LA L +T GNP+ +E Y+ VL + ++ D +T+ +R
Sbjct: 111 GNSIQRLGEVNKLAVLPRLRSLTLHGNPMEEEKGYRQYVLCTLSRITTFDFSGVTKADRT 170
Query: 138 MASVLAKKEEEKKRESHKQSLL 159
A V + + K+ KQ+ L
Sbjct: 171 TAEVWKRMNIKPKKAWTKQNTL 192
>gi|62899065 centrosomal protein 72 kDa [Homo sapiens]
Length = 647
Score = 48.1 bits (113), Expect = 2e-05
Identities = 38/143 (26%), Positives = 67/143 (46%), Gaps = 5/143 (3%)
Query: 24 LCELRVLNLARNFLSHVDNLN----GLDSLTELNLRHNQITFVRDVDNLPCLQHLFLSFN 79
L EL+ L++ + + +L L L L+L N + + + L L+ L L +N
Sbjct: 27 LAELQSLSIPGTYQEKITHLGHSLMSLTGLKSLDLSRNSLVSLEGIQYLTALESLNLYYN 86
Query: 80 NISSFDSVSCLADSSSLSDITFDGNPIAQ-ESWYKHTVLQNMMQLRQLDMKRITEEERRM 138
ISS V L + L D+ F NP+ + E Y+ V+ + +L+QLD + + ER+
Sbjct: 87 CISSLAEVFRLHALTELVDVDFRLNPVVKVEPDYRLFVVHLLPKLQQLDDRPVRASERKA 146
Query: 139 ASVLAKKEEEKKRESHKQSLLKE 161
+ + E+ + + LKE
Sbjct: 147 SRLHFASEDSLDSKESVPASLKE 169
Score = 33.5 bits (75), Expect = 0.45
Identities = 27/81 (33%), Positives = 37/81 (45%), Gaps = 9/81 (11%)
Query: 3 SNLDVLDLHGNQITKIENINHLCELRVLNLARNFLS---HVDNLNGLDSLTELNLRHNQI 59
+ L LDL N + +E I +L L LNL N +S V L+ L L +++ R N +
Sbjct: 54 TGLKSLDLSRNSLVSLEGIQYLTALESLNLYYNCISSLAEVFRLHALTELVDVDFRLNPV 113
Query: 60 TFVRD------VDNLPCLQHL 74
V V LP LQ L
Sbjct: 114 VKVEPDYRLFVVHLLPKLQQL 134
>gi|54607118 leucine-rich repeats and immunoglobulin-like domains 1
[Homo sapiens]
Length = 1093
Score = 47.8 bits (112), Expect = 2e-05
Identities = 45/132 (34%), Positives = 68/132 (51%), Gaps = 10/132 (7%)
Query: 3 SNLDVLDLHGNQITKIEN--INHLCELRVLNLARNFLSHVDN--LNGLDSLTELNLRHNQ 58
++L+VL L N I+K+ + L ++ VL+L N L V++ L GL +L +L+L +N
Sbjct: 235 NSLEVLKLQRNNISKLTDGAFWGLSKMHVLHLEYNSLVEVNSGSLYGLTALHQLHLSNNS 294
Query: 59 ITFVRDVDNLPC--LQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKHTV 116
I + C L L LSFNN++ D S LA+ SSLS + N I S
Sbjct: 295 IARIHRKGWSFCQKLHELVLSFNNLTRLDEES-LAELSSLSVLRLSHNSI---SHIAEGA 350
Query: 117 LQNMMQLRQLDM 128
+ + LR LD+
Sbjct: 351 FKGLRSLRVLDL 362
Score = 35.8 bits (81), Expect = 0.091
Identities = 35/90 (38%), Positives = 44/90 (48%), Gaps = 9/90 (10%)
Query: 3 SNLDVLDLHGNQITKIEN--INHLCELRVLNLARNFLSHVDN-----LNGLDSLTELNLR 55
S+L VL L N I+ I L LRVL+L N +S +GLDSL++L L
Sbjct: 331 SSLSVLRLSHNSISHIAEGAFKGLRSLRVLDLDHNEISGTIEDTSGAFSGLDSLSKLTLF 390
Query: 56 HNQITFV--RDVDNLPCLQHLFLSFNNISS 83
N+I V R L L+HL L N I S
Sbjct: 391 GNKIKSVAKRAFSGLEGLEHLNLGGNAIRS 420
>gi|51317373 netrin-G1 ligand [Homo sapiens]
Length = 640
Score = 46.6 bits (109), Expect = 5e-05
Identities = 48/192 (25%), Positives = 88/192 (45%), Gaps = 10/192 (5%)
Query: 1 MSSNLDVLDLHGNQIT--KIENINHLCELRVLNLARNFLSHVD--NLNGLDSLTELNLRH 56
+S+N +L+LH NQI K+ + HL L +L L+RN + ++ NGL +L L L
Sbjct: 74 ISTNTRLLNLHENQIQIIKVNSFKHLRHLEILQLSRNHIRTIEIGAFNGLANLNTLELFD 133
Query: 57 NQITFVRD--VDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIAQESWYKH 114
N++T + + L L+ L+L N I +S+ A + S D + + S+
Sbjct: 134 NRLTTIPNGAFVYLSKLKELWLRNNPI---ESIPSYAFNRIPSLRRLDLGELKRLSYISE 190
Query: 115 TVLQNMMQLRQLDMKRITEEERRMASVLAKKEEEKKRESHKQSLLKEKKRLTINNVARQW 174
+ + LR L++ E + L K +E +H S ++ + ++ + W
Sbjct: 191 GAFEGLSNLRYLNLAMCNLREIPNLTPLIKLDELDLSGNH-LSAIRPGSFQGLMHLQKLW 249
Query: 175 DLQQRVANIATN 186
+Q ++ I N
Sbjct: 250 MIQSQIQVIERN 261
Score = 32.7 bits (73), Expect = 0.77
Identities = 20/62 (32%), Positives = 34/62 (54%), Gaps = 4/62 (6%)
Query: 5 LDVLDLHGNQITKIE--NINHLCELRVLNLARNFLSHVDN--LNGLDSLTELNLRHNQIT 60
LD LDL GN ++ I + L L+ L + ++ + ++ + L SL E+NL HN +T
Sbjct: 221 LDELDLSGNHLSAIRPGSFQGLMHLQKLWMIQSQIQVIERNAFDNLQSLVEINLAHNNLT 280
Query: 61 FV 62
+
Sbjct: 281 LL 282
>gi|4758460 glycoprotein V (platelet) [Homo sapiens]
Length = 560
Score = 46.2 bits (108), Expect = 7e-05
Identities = 44/136 (32%), Positives = 62/136 (45%), Gaps = 20/136 (14%)
Query: 4 NLDVLDLHGNQITKIEN--INHLCELRVLNLARNFLSHVDN--LNGLDSLTELNLRHNQI 59
NL +LDL GN +T + + +L L L N L +D+ LN L +LTEL N I
Sbjct: 171 NLKLLDLSGNNLTHLPKGLLGAQAKLERLLLHSNRLVSLDSGLLNSLGALTELQFHRNHI 230
Query: 60 TFVRD--VDNLPCLQHLFLSFNNISSFDSVSCLADSSSLSDITFDGNPIA---------- 107
+ D LP L L LS N+++ S L S +L+ +T NP+A
Sbjct: 231 RSIAPGAFDRLPNLSSLTLSRNHLAFLPSALFL-HSHNLTLLTLFENPLAELPGVLFGEM 289
Query: 108 ---QESWYKHTVLQNM 120
QE W T L+ +
Sbjct: 290 GGLQELWLNRTQLRTL 305
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.316 0.132 0.371
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,463,412
Number of Sequences: 37866
Number of extensions: 707450
Number of successful extensions: 5450
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 58
Number of HSP's successfully gapped in prelim test: 206
Number of HSP's that attempted gapping in prelim test: 4814
Number of HSP's gapped (non-prelim): 718
length of query: 489
length of database: 18,247,518
effective HSP length: 106
effective length of query: 383
effective length of database: 14,233,722
effective search space: 5451515526
effective search space used: 5451515526
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.