Guide to the Human Genome
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Search of human proteins with 239749695

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239749695 PREDICTED: hypothetical protein XP_002347121 [Homo
sapiens]
         (594 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239749695 PREDICTED: hypothetical protein XP_002347121 [Homo ...  1222   0.0  
gi|239743961 PREDICTED: hypothetical protein XP_002344246 [Homo ...  1222   0.0  
gi|110832843 TBP-associated factor 4 [Homo sapiens]                    66   8e-11
gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]    63   7e-10
gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]      60   6e-09
gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]       56   1e-07
gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Ho...    55   1e-07
gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Ho...    55   1e-07
gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Ho...    55   1e-07
gi|239748756 PREDICTED: hypothetical protein XP_002346788 [Homo ...    54   3e-07
gi|239742799 PREDICTED: hypothetical protein XP_002342652 [Homo ...    54   3e-07
gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein ...    54   3e-07
gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein ...    54   3e-07
gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein ...    54   3e-07
gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]            54   4e-07
gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Hom...    54   5e-07
gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Hom...    54   5e-07
gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]            54   5e-07
gi|239750574 PREDICTED: hypothetical protein [Homo sapiens]            53   9e-07
gi|169205732 PREDICTED: hypothetical protein [Homo sapiens]            53   9e-07
gi|91208420 bassoon protein [Homo sapiens]                             52   1e-06
gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]      52   2e-06
gi|156071470 hyperpolarization activated cyclic nucleotide-gated...    52   2e-06
gi|48762934 alpha 2 type I collagen [Homo sapiens]                     50   4e-06
gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]            50   4e-06
gi|239753839 PREDICTED: hypothetical protein [Homo sapiens]            50   4e-06
gi|71043876 undifferentiated embryonic cell transcription factor...    50   4e-06
gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]            50   6e-06
gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]            50   6e-06
gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]       50   8e-06

>gi|239749695 PREDICTED: hypothetical protein XP_002347121 [Homo
           sapiens]
          Length = 594

 Score = 1222 bits (3161), Expect = 0.0
 Identities = 594/594 (100%), Positives = 594/594 (100%)

Query: 1   MGRIPRRPQPAGSTSTDILYGLCGHLLDAGDEGGQAGHPVVGDTGQFERGCARRHRSPRG 60
           MGRIPRRPQPAGSTSTDILYGLCGHLLDAGDEGGQAGHPVVGDTGQFERGCARRHRSPRG
Sbjct: 1   MGRIPRRPQPAGSTSTDILYGLCGHLLDAGDEGGQAGHPVVGDTGQFERGCARRHRSPRG 60

Query: 61  HRHAVPGPRLQRALGGQAWAGRRQLHGFMLYSGQQRDGHRGGHDVGGRGGGGRLQLVAGA 120
           HRHAVPGPRLQRALGGQAWAGRRQLHGFMLYSGQQRDGHRGGHDVGGRGGGGRLQLVAGA
Sbjct: 61  HRHAVPGPRLQRALGGQAWAGRRQLHGFMLYSGQQRDGHRGGHDVGGRGGGGRLQLVAGA 120

Query: 121 LGLGAGVLDHSGLRVAVGRAHLEHEVGAALHDVLDLQEAGRVHDHELLAGRHGEPARVAE 180
           LGLGAGVLDHSGLRVAVGRAHLEHEVGAALHDVLDLQEAGRVHDHELLAGRHGEPARVAE
Sbjct: 121 LGLGAGVLDHSGLRVAVGRAHLEHEVGAALHDVLDLQEAGRVHDHELLAGRHGEPARVAE 180

Query: 181 GQDLLEAGGRHGAGQLEGALAVAAEQVAEVEAAGGQHRPVGLEGLALDHDGHIAVEAQQA 240
           GQDLLEAGGRHGAGQLEGALAVAAEQVAEVEAAGGQHRPVGLEGLALDHDGHIAVEAQQA
Sbjct: 181 GQDLLEAGGRHGAGQLEGALAVAAEQVAEVEAAGGQHRPVGLEGLALDHDGHIAVEAQQA 240

Query: 241 LLVQAAQHCVPEVGDLDVQHLRHGGRAAAGLGSQRGAALAGLIYLPSAAAAAGRHCPLRL 300
           LLVQAAQHCVPEVGDLDVQHLRHGGRAAAGLGSQRGAALAGLIYLPSAAAAAGRHCPLRL
Sbjct: 241 LLVQAAQHCVPEVGDLDVQHLRHGGRAAAGLGSQRGAALAGLIYLPSAAAAAGRHCPLRL 300

Query: 301 AGQAPRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQA 360
           AGQAPRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQA
Sbjct: 301 AGQAPRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQA 360

Query: 361 GARVGEAREAVTTHERAHLDREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGP 420
           GARVGEAREAVTTHERAHLDREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGP
Sbjct: 361 GARVGEAREAVTTHERAHLDREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGP 420

Query: 421 WDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPE 480
           WDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPE
Sbjct: 421 WDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPE 480

Query: 481 RWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPR 540
           RWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPR
Sbjct: 481 RWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPR 540

Query: 541 PRPDSLSPGEPPGPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
           PRPDSLSPGEPPGPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP
Sbjct: 541 PRPDSLSPGEPPGPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594


>gi|239743961 PREDICTED: hypothetical protein XP_002344246 [Homo
           sapiens]
          Length = 594

 Score = 1222 bits (3161), Expect = 0.0
 Identities = 594/594 (100%), Positives = 594/594 (100%)

Query: 1   MGRIPRRPQPAGSTSTDILYGLCGHLLDAGDEGGQAGHPVVGDTGQFERGCARRHRSPRG 60
           MGRIPRRPQPAGSTSTDILYGLCGHLLDAGDEGGQAGHPVVGDTGQFERGCARRHRSPRG
Sbjct: 1   MGRIPRRPQPAGSTSTDILYGLCGHLLDAGDEGGQAGHPVVGDTGQFERGCARRHRSPRG 60

Query: 61  HRHAVPGPRLQRALGGQAWAGRRQLHGFMLYSGQQRDGHRGGHDVGGRGGGGRLQLVAGA 120
           HRHAVPGPRLQRALGGQAWAGRRQLHGFMLYSGQQRDGHRGGHDVGGRGGGGRLQLVAGA
Sbjct: 61  HRHAVPGPRLQRALGGQAWAGRRQLHGFMLYSGQQRDGHRGGHDVGGRGGGGRLQLVAGA 120

Query: 121 LGLGAGVLDHSGLRVAVGRAHLEHEVGAALHDVLDLQEAGRVHDHELLAGRHGEPARVAE 180
           LGLGAGVLDHSGLRVAVGRAHLEHEVGAALHDVLDLQEAGRVHDHELLAGRHGEPARVAE
Sbjct: 121 LGLGAGVLDHSGLRVAVGRAHLEHEVGAALHDVLDLQEAGRVHDHELLAGRHGEPARVAE 180

Query: 181 GQDLLEAGGRHGAGQLEGALAVAAEQVAEVEAAGGQHRPVGLEGLALDHDGHIAVEAQQA 240
           GQDLLEAGGRHGAGQLEGALAVAAEQVAEVEAAGGQHRPVGLEGLALDHDGHIAVEAQQA
Sbjct: 181 GQDLLEAGGRHGAGQLEGALAVAAEQVAEVEAAGGQHRPVGLEGLALDHDGHIAVEAQQA 240

Query: 241 LLVQAAQHCVPEVGDLDVQHLRHGGRAAAGLGSQRGAALAGLIYLPSAAAAAGRHCPLRL 300
           LLVQAAQHCVPEVGDLDVQHLRHGGRAAAGLGSQRGAALAGLIYLPSAAAAAGRHCPLRL
Sbjct: 241 LLVQAAQHCVPEVGDLDVQHLRHGGRAAAGLGSQRGAALAGLIYLPSAAAAAGRHCPLRL 300

Query: 301 AGQAPRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQA 360
           AGQAPRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQA
Sbjct: 301 AGQAPRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQA 360

Query: 361 GARVGEAREAVTTHERAHLDREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGP 420
           GARVGEAREAVTTHERAHLDREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGP
Sbjct: 361 GARVGEAREAVTTHERAHLDREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGP 420

Query: 421 WDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPE 480
           WDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPE
Sbjct: 421 WDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPE 480

Query: 481 RWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPR 540
           RWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPR
Sbjct: 481 RWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPR 540

Query: 541 PRPDSLSPGEPPGPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
           PRPDSLSPGEPPGPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP
Sbjct: 541 PRPDSLSPGEPPGPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594


>gi|110832843 TBP-associated factor 4 [Homo sapiens]
          Length = 1085

 Score = 66.2 bits (160), Expect = 8e-11
 Identities = 94/332 (28%), Positives = 111/332 (33%), Gaps = 47/332 (14%)

Query: 279 LAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLH 338
           L G +    AA+AA  H    LA + P  + A   A         P G  GAG       
Sbjct: 25  LVGSLESQLAASAAHHH---HLAPRTPEVRAAAAGALGNHVVSGSPAGAAGAG------- 74

Query: 339 DESPRPNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDREGEARARLGQAAAQMRR 398
                   P + AEG   +       G AR      +R             G A      
Sbjct: 75  --------PAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPP---- 122

Query: 399 EGWGARAKLGGRGVCGKCGPGPWDDP-ARRRNPGAAARAKLAGQRAGRARARTGSQVGSR 457
               A+ +    G  G C P P     A    P  A  AK AG  A  ARA  G   G  
Sbjct: 123 ---AAKLRPPPEGSAGSCAPVPAAAAVAAGPEPAPAGPAKPAGPAALAARAGPGPGPGP- 178

Query: 458 GRGWGPGAGRVPSGGRRGVGNPERW---GGEAAAPRPSRV------LLPELPAVDPARDT 508
           G G GPG G+    G     N          AAAP  S V      LLP      P    
Sbjct: 179 GPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGPAALLPLPKPAAPGTVI 238

Query: 509 RREPDAAAQRTELGGR----VGKGPGAPPSALPGPRPRPDSLS--PGEPPGPPT-----P 557
           +  P   A                P AP +A P P P P +L+  PG P GPPT     P
Sbjct: 239 QTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLARPPGHPAGPPTAAPAVP 298

Query: 558 PPARALPAAVASARCSLRDPGGGSARIRSRPG 589
           PPA A     A A  +     GG A +  +PG
Sbjct: 299 PPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPG 330



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 85/321 (26%), Positives = 102/321 (31%), Gaps = 63/321 (19%)

Query: 286 PSAAAAAGRHCPLRLA-GQAPRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRP 344
           P+ AA AG   P   A G AP   PA  A P          GG G          + P P
Sbjct: 67  PAGAAGAGPAAPAEGAPGAAPEPPPAGRARP----------GGGGP---------QRPGP 107

Query: 345 NFPQSLAEGLGVSPQAGAR----VGEAREAVTTHERAHLDREGEARARLGQAAAQMRREG 400
             P+      G +P A        G A         A +   G   A  G A    +  G
Sbjct: 108 PSPRRPLVPAGPAPPAAKLRPPPEGSAGSCAPVPAAAAV-AAGPEPAPAGPA----KPAG 162

Query: 401 WGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAA--RAKLAGQRAGRARARTGSQVGSRG 458
             A A   G G     GPGP   P +   PGAA       A   +  A A   S V +  
Sbjct: 163 PAALAARAGPGPGPGPGPGPGPGPGKPAGPGAAQTLNGSAALLNSHHAAAPAVSLVNNGP 222

Query: 459 RGWGP-----------------GAGRVPSGGRRGVGNPERWGGEAAAPRP------SRVL 495
               P                 GA   P+               AAAP P      +   
Sbjct: 223 AALLPLPKPAAPGTVIQTPPFVGAAAPPAPAAPSPPAAPAPAAPAAAPPPPPPAPATLAR 282

Query: 496 LPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGP-----RPRPDSLSPGE 550
            P  PA  P       P AAAQ    GG  G  P AP  A  GP     +P P + +   
Sbjct: 283 PPGHPAGPPTAAPAVPPPAAAQN---GGSAGAAP-APAPAAGGPAGVSGQPGPGAAAAAP 338

Query: 551 PPGPPTPPPARALPAAVASAR 571
            PG     P R + AA  +A+
Sbjct: 339 APGVKAESPKRVVQAAPPAAQ 359



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 24/88 (27%), Positives = 28/88 (31%), Gaps = 18/88 (20%)

Query: 523 GRVGKGPGAPPSALPGPRPRPDSLSPGEP-------PGPPTP-----------PPARALP 564
           G  G GP AP    PG  P P       P       PGPP+P           P A+  P
Sbjct: 69  GAAGAGPAAPAEGAPGAAPEPPPAGRARPGGGGPQRPGPPSPRRPLVPAGPAPPAAKLRP 128

Query: 565 AAVASARCSLRDPGGGSARIRSRPGRSG 592
               SA      P   +      P  +G
Sbjct: 129 PPEGSAGSCAPVPAAAAVAAGPEPAPAG 156



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 42/159 (26%), Positives = 55/159 (34%), Gaps = 20/159 (12%)

Query: 430 PGAAARAKLAGQRAGRARARTGSQVGSRGRGWGP-GAGRVPS---GGRRGVGNPERWGGE 485
           P  A  A+  G  AG   A       +  +  G  GA   P+   GG  GV      G  
Sbjct: 275 PAPATLARPPGHPAGPPTAAPAVPPPAAAQNGGSAGAAPAPAPAAGGPAGVSGQPGPGAA 334

Query: 486 AAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELG----------GRVGKGPGAPPSA 535
           AAAP P       + A  P R  +  P AA      G          G   +G    P+A
Sbjct: 335 AAAPAPG------VKAESPKRVVQAAPPAAQTLAASGPASTAASMVIGPTMQGALPSPAA 388

Query: 536 LPGPRPRPDSLSPGEPPGPPTPPPARALPAAVASARCSL 574
           +P P P   +  P    G  T   +R   A  +  R +L
Sbjct: 389 VPPPAPGTPTGLPKGAAGAVTQSLSRTPTATTSGIRATL 427


>gi|110735435 collagen, type V, alpha 3 preproprotein [Homo sapiens]
          Length = 1745

 Score = 63.2 bits (152), Expect = 7e-10
 Identities = 73/233 (31%), Positives = 91/233 (39%), Gaps = 37/233 (15%)

Query: 386 RARLGQAAAQMRREGWGARAKLGGRGVCGKCG----------PGPWDDPARRRNPGAAAR 435
           + + GQA  +      G + KLG  G+ G  G          PGP      +   G   +
Sbjct: 766 KGQAGQAGEEGPPGSAGEKGKLGVPGLPGYPGRPGPKGSIGFPGPLGPIGEKGKSGKTGQ 825

Query: 436 AKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWG--GEAAAPR--- 490
             L G+R            GSRG    PGA   P G +  VG     G  GE   P    
Sbjct: 826 PGLEGERG---------PPGSRGERGQPGATGQP-GPKGDVGQDGAPGIPGEKGLPGLQG 875

Query: 491 PSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSP-G 549
           P     P+ P     +D R  P    QR ELG +   GP  P   L GP+ +   + P G
Sbjct: 876 PPGFPGPKGPPGHQGKDGR--PGHPGQRGELGFQGQTGPPGPAGVL-GPQGKTGEVGPLG 932

Query: 550 E--PPGPPTPPPARALPAAVA--SARCSLRDPG----GGSARIRSRPGRSGGP 594
           E  PPGPP PP  + LP       A+  L  PG     G A +R  PG  GGP
Sbjct: 933 ERGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGP 985



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 78/334 (23%), Positives = 101/334 (30%), Gaps = 56/334 (16%)

Query: 300  LAGQAPRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQ 359
            L GQ+    P  PA  +  + ER P G  G         D  P P  P       G S +
Sbjct: 1023 LPGQSGSEGPVGPAGKKGSRGERGPPGPTGK--------DGIPGPLGPLGPPGAAGPSGE 1074

Query: 360  AGAR--VGEAREAVTTHERAHLDREGEARAR--------LGQAAAQMRREG---WGARAK 406
             G +  VG      +  ++      G+   R         G   AQ RR     +G +  
Sbjct: 1075 EGDKGDVGAPGHKGSKGDKGDAGPPGQPGIRGPAGHPGPPGADGAQGRRGPPGLFGQKGD 1134

Query: 407  LGGRGVCGKCGP----------------------GPWDDPARRRNPGAAARAKLAGQRAG 444
             G RG  G  GP                      GP   P  R   G        G   G
Sbjct: 1135 DGVRGFVGVIGPPGLQGLPGPPGEKGEVGDVGSMGPHGAPGPRGPQGPTGSEGTPGLPGG 1194

Query: 445  RARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDP 504
              +     + G RG    PG    P     G+  P+   GE     PS    P      P
Sbjct: 1195 VGQPGAVGEKGERGDAGDPGPPGAP-----GIPGPKGDIGEKGDSGPSGAAGPPGKKGPP 1249

Query: 505  ARDTRREPDAAAQRTELGGRVGKGPGAPP----SALPGPRPRPDSLSPGEPPGPPTPPPA 560
              D  +    +   T L G +G  PG P        PG +  P  +    PPG    P A
Sbjct: 1250 GEDGAK---GSVGPTGLPGDLGP-PGDPGVSGIDGSPGEKGDPGDVGGPGPPGASGEPGA 1305

Query: 561  RALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
               P     +    R+   G    +  PG  G P
Sbjct: 1306 PGPPGKRGPSGHMGREGREGEKGAKGEPGPDGPP 1339



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 51/182 (28%), Positives = 62/182 (34%), Gaps = 20/182 (10%)

Query: 391 QAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARART 450
           QA A +++     +   G  G+ G+  PGP   P      G        G R  +     
Sbjct: 465 QAQAVLQQTQLSMKGPPGPVGLTGR--PGPVGLPGHPGLKGEEGAEGPQGPRGLQGPHGP 522

Query: 451 GSQVGSRGRGWGPGAGRVPSG----GRRGV-GNPERWGGEAAAPRPSRVLLPELPAVDPA 505
             +VG  GR    GA  +P      G RG  G P   G +        V  P  P  D  
Sbjct: 523 PGRVGKMGRPGADGARGLPGDTGPKGDRGFDGLPGLPGEKGQRGDFGHVGQPGPPGEDGE 582

Query: 506 RDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSL----SPGE-----PPGPPT 556
           R     P    Q  E G R   GP   P    GP  RP       +PG      PPG P 
Sbjct: 583 RGAEGPPGPTGQAGEPGPRGLLGPRGSP----GPTGRPGVTGIDGAPGAKGNVGPPGEPG 638

Query: 557 PP 558
           PP
Sbjct: 639 PP 640



 Score = 37.0 bits (84), Expect = 0.051
 Identities = 62/227 (27%), Positives = 80/227 (35%), Gaps = 42/227 (18%)

Query: 388  RLGQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRAR 447
            + GQ   +  R   G+R + G  G  G+  PGP  D  +   PG      L G +     
Sbjct: 822  KTGQPGLEGERGPPGSRGERGQPGATGQ--PGPKGDVGQDGAPGIPGEKGLPGLQGPPGF 879

Query: 448  ARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPE--LPAVDPA 505
                   G +G+   PG      G R  +G    + G+   P P+ VL P+     V P 
Sbjct: 880  PGPKGPPGHQGKDGRPGH----PGQRGELG----FQGQTGPPGPAGVLGPQGKTGEVGPL 931

Query: 506  RDTRREPDAAAQRTELG-----GRVG-KGPGAPPSAL-----------PGPRPRPDSLSP 548
             + R  P       E G     GR G KG   PP  L           PGP+  P    P
Sbjct: 932  GE-RGPPGPPGPPGEQGLPGLEGREGAKGELGPPGPLGKEGPAGLRGFPGPKGGPGDPGP 990

Query: 549  ---GEPPGPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSG 592
                   GPP P  A   P          R P G +  I   PG+SG
Sbjct: 991  TGLKGDKGPPGPVGANGSPGE--------RGPLGPAGGI-GLPGQSG 1028



 Score = 34.3 bits (77), Expect = 0.33
 Identities = 54/196 (27%), Positives = 63/196 (32%), Gaps = 38/196 (19%)

Query: 400  GWGARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRG 458
            G G     G +G  G  GP G    P  R   G A    L GQ           + GSRG
Sbjct: 984  GPGDPGPTGLKGDKGPPGPVGANGSPGERGPLGPAGGIGLPGQSGSEGPVGPAGKKGSRG 1043

Query: 459  RGWGPG-------------------AGRVPSGGRRG-VGNPERWG-----GEAAAPRPSR 493
                PG                   AG     G +G VG P   G     G+A  P    
Sbjct: 1044 ERGPPGPTGKDGIPGPLGPLGPPGAAGPSGEEGDKGDVGAPGHKGSKGDKGDAGPPGQPG 1103

Query: 494  VL----LPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPP--SALPGPRPRP---- 543
            +      P  P  D A+  R  P    Q+ + G R   G   PP    LPGP        
Sbjct: 1104 IRGPAGHPGPPGADGAQGRRGPPGLFGQKGDDGVRGFVGVIGPPGLQGLPGPPGEKGEVG 1163

Query: 544  --DSLSPGEPPGPPTP 557
               S+ P   PGP  P
Sbjct: 1164 DVGSMGPHGAPGPRGP 1179



 Score = 33.9 bits (76), Expect = 0.43
 Identities = 51/207 (24%), Positives = 62/207 (29%), Gaps = 40/207 (19%)

Query: 378  HLDREGE-----ARARLGQAAAQMRREGWGARAKLGG------RGVCGKCG-PGPWDDPA 425
            H+ REG      A+   G      R    GAR   G       RG+ G  G PG    P 
Sbjct: 1317 HMGREGREGEKGAKGEPGPDGPPGRTGPMGARGPPGRVGPEGLRGIPGPVGEPGLLGAPG 1376

Query: 426  RRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPG-AGRVPSGGRRGVGNPERWGG 484
            +   PG    + L G +           +G  G    PG AG     G  GV  P    G
Sbjct: 1377 QMGPPGPLGPSGLPGLKGDTGPKGEKGHIGLIGLIGPPGEAGEKGDQGLPGVQGPPGPKG 1436

Query: 485  EAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPD 544
            +   P P   L                           G  G    A P    G +  P 
Sbjct: 1437 DPGPPGPIGSL---------------------------GHPGPPGVAGPLGQKGSKGSPG 1469

Query: 545  SLSPGEPPGPPTPPPARALPAAVASAR 571
            S+ P    GP  PP     PA +   R
Sbjct: 1470 SMGPRGDTGPAGPPGPPGAPAELHGLR 1496


>gi|4502951 collagen type III alpha 1 preproprotein [Homo sapiens]
          Length = 1466

 Score = 60.1 bits (144), Expect = 6e-09
 Identities = 102/396 (25%), Positives = 126/396 (31%), Gaps = 86/396 (21%)

Query: 264 GGRAAAGL----GSQRGAALAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQ- 318
           G R AAG     G   G  + G+   P    + G+  P    G++ R  P  P+ PR Q 
Sbjct: 516 GPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGSDGKPGPPGSQGESGRPGPPGPSGPRGQP 575

Query: 319 -----------------QTEREPWGGEGAGSRFKRLHDESPR----------------PN 345
                              ER   GG G      +  +  P+                P 
Sbjct: 576 GVMGFPGPKGNDGAPGKNGERGGPGGPGPQGPPGKNGETGPQGPPGPTGPGGDKGDTGPP 635

Query: 346 FPQSLA--EGLGVSPQAGARVGEAREAVTTHERAHLDREGEA-----RARLGQAAAQMRR 398
            PQ L    G G  P    + GE               +G+A     R   G A A   R
Sbjct: 636 GPQGLQGLPGTGGPPGENGKPGEPGPKGDAGAPGAPGGKGDAGAPGERGPPGLAGAPGLR 695

Query: 399 EGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRG 458
            G G     GG+G  G  GP           PGAA    L G    R    +    G +G
Sbjct: 696 GGAGPPGPEGGKGAAGPPGP-----------PGAAGTPGLQGMPGERGGLGSPGPKGDKG 744

Query: 459 RGWGPGAGRVP-SGGRRGVGNPERWGGEAAAP-RPSRVLLPELPAVDPARDTRRE----- 511
              GPGA  VP   G RG   P    G A  P        P LP +   R +  E     
Sbjct: 745 EPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPGIAGPRGSPGERGETG 804

Query: 512 -------PDAAAQRTELGGR------VGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPP 558
                  P A  Q  E GG+        KG G PP  + GP   P    P  PPGP    
Sbjct: 805 PPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPP-GVAGP---PGGSGPAGPPGPQGVK 860

Query: 559 PARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
             R  P    +A         G+  +   PG +G P
Sbjct: 861 GERGSPGGPGAAGFP------GARGLPGPPGSNGNP 890



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 97/372 (26%), Positives = 120/372 (32%), Gaps = 55/372 (14%)

Query: 264  GGRAAAGLGSQRGAALAGLIYLPSAAAAAGRHCPLRLAGQA-PRTQPACPAAPRMQQTER 322
            GG+  AG   +RG    GL   P     AG   P    G A P   P     P +Q    
Sbjct: 672  GGKGDAGAPGERGPP--GLAGAPGLRGGAGPPGPEGGKGAAGPPGPPGAAGTPGLQGMPG 729

Query: 323  EPWGGEGAGSRFKRLH------DESPRPNFPQSLAEGLGVSPQAG-----------ARVG 365
            E  G    G +  +        D  P  + P+     +G    AG              G
Sbjct: 730  ERGGLGSPGPKGDKGEPGGPGADGVPGKDGPRGPTGPIGPPGPAGQPGDKGEGGAPGLPG 789

Query: 366  EAREAVTTHERAHLDREGEAR-----ARLGQAAAQMRREGWGARAKLGGRGVCGKCG--- 417
             A    +  ER      G A       + G+   +  R   G + + G  GV G  G   
Sbjct: 790  IAGPRGSPGERGETGPPGPAGFPGAPGQNGEPGGKGERGAPGEKGEGGPPGVAGPPGGSG 849

Query: 418  ----PGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGR 473
                PGP      R +PG    A   G     AR   G   GS G    PG    PSG  
Sbjct: 850  PAGPPGPQGVKGERGSPGGPGAAGFPG-----ARGLPGPP-GSNGNPGPPG----PSGSP 899

Query: 474  RGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTR---REPDAAAQRTELGGRVGKGPG 530
             G   P    G   AP    V  P+  A  P        + P  A     + G  G    
Sbjct: 900  -GKDGPPGPAGNTGAPGSPGVSGPKGDAGQPGEKGSPGAQGPPGAPGPLGIAGITGARGL 958

Query: 531  APPSALPGPRPRP-------DSLSPGEP--PGPPTPPPARALPAAVASARCSLRDPGGGS 581
            A P  +PGPR  P       +S  PG     G   PP  + LP    +A    RD   GS
Sbjct: 959  AGPPGMPGPRGSPGPQGVKGESGKPGANGLSGERGPPGPQGLPGLAGTAGEPGRDGNPGS 1018

Query: 582  ARIRSRPGRSGG 593
              +  R G  GG
Sbjct: 1019 DGLPGRDGSPGG 1030



 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 97/356 (27%), Positives = 110/356 (30%), Gaps = 55/356 (15%)

Query: 264 GGRAAAGLGSQRGAALAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTERE 323
           G   A GL  + G        LP    A G   P    G+  R +P  P A   +     
Sbjct: 276 GETGAPGLKGENG--------LPGENGAPGPMGPRGAPGE--RGRPGLPGAAGAR----- 320

Query: 324 PWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDREG 383
             G +GA     R  D  P P  P   A G   SP A   VG A    +          G
Sbjct: 321 --GNDGA-----RGSDGQPGPPGPPGTA-GFPGSPGAKGEVGPAGSPGSNGAPGQRGEPG 372

Query: 384 EARARLGQAAAQMRREGWGARAKLGGRGVCGKCG-PGPWDDPARRRNPGAAARAKLAGQR 442
                 G A AQ      G     GG+G  G  G PG       R  PG A      G R
Sbjct: 373 PQ----GHAGAQGPPGPPGINGSPGGKGEMGPAGIPGAPGLMGARGPPGPAGANGAPGLR 428

Query: 443 AGR-------ARARTGSQVGSRGRGWGPGA-------GRVPSGGRRGVGNPERWGGEAAA 488
            G        A+   G + G RG    PG        G+  S G  G        GE  A
Sbjct: 429 GGAGEPGKNGAKGEPGPR-GERGEAGIPGVPGAKGEDGKDGSPGEPGANGLPGAAGERGA 487

Query: 489 PRPSRVLLPE-LPAVDPARDTRREPDAAAQRTELG--GRVGKGPGAPPSALPGPRPRPDS 545
           P       P  +P        R  P  A  R   G  GR G   G     +PG    P S
Sbjct: 488 PGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGEPGRDGVPGGPGMRGMPGSPGGPGS 547

Query: 546 LS-PGEP--------PGPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSG 592
              PG P        PGPP P   R  P  +        D   G    R  PG  G
Sbjct: 548 DGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNGERGGPGGPG 603



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 48/165 (29%), Positives = 57/165 (34%), Gaps = 13/165 (7%)

Query: 408  GGRGVCGKCG-PGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAG 466
            GG+G  G+ G PG    P     PG    A  +G R     A      G  G    PG  
Sbjct: 1029 GGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGP- 1087

Query: 467  RVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELG---- 522
            + P G +   G     G +     P     P  P     +     P  A  R  +G    
Sbjct: 1088 QGPRGDKGETGERGAAGIKGHRGFPGNPGAPGSPGPAGQQGAIGSPGPAGPRGPVGPSGP 1147

Query: 523  -GRVGKGPGAPPSALPGPR----PRPDSLSPGEP--PGPPTPPPA 560
             G+ G      P   PGPR     R    SPG P  PGPP PP A
Sbjct: 1148 PGKDGTSGHPGPIGPPGPRGNRGERGSEGSPGHPGQPGPPGPPGA 1192



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 48/158 (30%), Positives = 53/158 (33%), Gaps = 17/158 (10%)

Query: 402 GARAKLGGRGVCGKCG-PGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRG 460
           G R   G RG  G  G PG       R  PG A     AG+  GR     G   G RG  
Sbjct: 483 GERGAPGFRGPAGPNGIPGEKGPAGERGAPGPAGPRGAAGE-PGRDGVPGGP--GMRGMP 539

Query: 461 WGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPE-LPAVDPARDTRREPDAAAQRT 519
             PG       G  G   P    GE+  P P     P   P V      +    A  +  
Sbjct: 540 GSPGGP-----GSDGKPGPPGSQGESGRPGPPGPSGPRGQPGVMGFPGPKGNDGAPGKNG 594

Query: 520 ELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTP 557
           E GG  G GP  PP        +     P  PPGP  P
Sbjct: 595 ERGGPGGPGPQGPPG-------KNGETGPQGPPGPTGP 625



 Score = 38.9 bits (89), Expect = 0.013
 Identities = 88/352 (25%), Positives = 111/352 (31%), Gaps = 52/352 (14%)

Query: 264  GGRAAAGLGSQRGAALAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTERE 323
            GG  AAG    RG        LP    + G   P   +G   +  P  PA          
Sbjct: 867  GGPGAAGFPGARG--------LPGPPGSNGNPGPPGPSGSPGKDGPPGPAGNTGAPGSPG 918

Query: 324  PWGGEG-AGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDRE 382
              G +G AG   ++    SP    P      LG++   GAR G A        R     +
Sbjct: 919  VSGPKGDAGQPGEK---GSPGAQGPPGAPGPLGIAGITGAR-GLAGPPGMPGPRGSPGPQ 974

Query: 383  GEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQR 442
            G  +   G+  A       G R   G +G+ G  G     +P R  NPG+       G  
Sbjct: 975  G-VKGESGKPGANGLS---GERGPPGPQGLPGLAGTA--GEPGRDGNPGSDGLPGRDGSP 1028

Query: 443  AGRARARTGSQVGSRGRGWGPGA-GRVPSGGRRGVGNPERWGGEAAAPRPSR---VLLPE 498
             G+         G+ G    PG  G V   G+ G        G A AP P+       P+
Sbjct: 1029 GGKGDRGENGSPGAPGAPGHPGPPGPVGPAGKSGDRGESGPAGPAGAPGPAGSRGAPGPQ 1088

Query: 499  LPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSA-------LPGPRPRPDSLSPGEP 551
             P  D      R            G  G  PG+P  A        PGP      + P  P
Sbjct: 1089 GPRGDKGETGERGAAGIKGHRGFPGNPG-APGSPGPAGQQGAIGSPGPAGPRGPVGPSGP 1147

Query: 552  PG---------PPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
            PG         P  PP     P      R S   PG         PG+ G P
Sbjct: 1148 PGKDGTSGHPGPIGPPG----PRGNRGERGSEGSPG--------HPGQPGPP 1187



 Score = 33.5 bits (75), Expect = 0.57
 Identities = 50/207 (24%), Positives = 60/207 (28%), Gaps = 24/207 (11%)

Query: 408 GGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRG-RGWGPGAG 466
           G  G  G  GP   D  + R  PG      L G    +  A      G +G RG+    G
Sbjct: 216 GPPGAIGPSGPAGKDGESGR--PGRPGERGLPGPPGIKGPAGIPGFPGMKGHRGFDGRNG 273

Query: 467 RVPSGGRRGVGNPERWGGEAAAP-------RPSRVLLPELPAV------DPARDTRREPD 513
                G  G+       GE  AP        P     P LP        D AR +  +P 
Sbjct: 274 EKGETGAPGLKGENGLPGENGAPGPMGPRGAPGERGRPGLPGAAGARGNDGARGSDGQPG 333

Query: 514 AAAQRTELG--------GRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARALPA 565
                   G        G VG       +  PG R  P         GPP PP     P 
Sbjct: 334 PPGPPGTAGFPGSPGAKGEVGPAGSPGSNGAPGQRGEPGPQGHAGAQGPPGPPGINGSPG 393

Query: 566 AVASARCSLRDPGGGSARIRSRPGRSG 592
                  +      G    R  PG +G
Sbjct: 394 GKGEMGPAGIPGAPGLMGARGPPGPAG 420



 Score = 29.6 bits (65), Expect = 8.2
 Identities = 47/169 (27%), Positives = 56/169 (33%), Gaps = 37/169 (21%)

Query: 446 ARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPA 505
           A  R  +  G +G    PG   +P  GR G        G   +P P     P +    P 
Sbjct: 94  APTRPPNGQGPQGPKGDPGPPGIP--GRNGDPGIPGQPGSPGSPGP-----PGICESCPT 146

Query: 506 RDTRREPDAAAQRTELGGRVGKGPGAP-PSALPGPRPRPDSLS--------------PGE 550
                 P   +   + G  VG   G P P+  PGP P P   S              PGE
Sbjct: 147 GPQNYSPQYDSYDVKSGVAVGGLAGYPGPAGPPGP-PGPPGTSGHPGSPGSPGYQGPPGE 205

Query: 551 P-----PGPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
           P      GPP PP A   P+  A        PG        RPG  G P
Sbjct: 206 PGQAGPSGPPGPPGAIG-PSGPAGKDGESGRPG--------RPGERGLP 245


>gi|89276751 alpha 1 type V collagen preproprotein [Homo sapiens]
          Length = 1838

 Score = 55.8 bits (133), Expect = 1e-07
 Identities = 58/195 (29%), Positives = 72/195 (36%), Gaps = 35/195 (17%)

Query: 402  GARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGW 461
            GA  + GGRG  GK GP        +R P         G R  R       + G +G   
Sbjct: 892  GANGEKGGRGTPGKPGP------RGQRGP--------TGPRGERGPRGITGKPGPKGNSG 937

Query: 462  GPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTEL 521
            G G    P  G RG   P+   G    P P        P   P +D    P    QR E 
Sbjct: 938  GDGPAGPP--GERGPNGPQ---GPTGFPGPKG------PPGPPGKDGL--PGHPGQRGET 984

Query: 522  GGRVGKGPGAPPSALPGPRPRPDSLSPGE--PPGPPTPPPARALPAAVASARCSLRDPGG 579
            G +   GP  PP  +    P  ++   GE   PGPP PP  + LP  +A    +  DPG 
Sbjct: 985  GFQGKTGPPGPPGVVGPQGPTGETGPMGERGHPGPPGPPGEQGLP-GLAGKEGTKGDPGP 1043

Query: 580  GSARIRSRPGRSGGP 594
                    PG+ G P
Sbjct: 1044 AGL-----PGKDGPP 1053



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 55/203 (27%), Positives = 67/203 (33%), Gaps = 12/203 (5%)

Query: 402  GARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGW 461
            G   + G  G  G+  PGP   P +R  PG A      G++  +  A      G  G   
Sbjct: 1369 GEPGQTGSPGPTGE--PGPSGPPGKRGPPGPAGPEGRQGEKGAKGEAGLEGPPGKTGPIG 1426

Query: 462  GPGA-GRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTE 520
              GA G+    G RG+  P    G   +P P     P  P   P       P        
Sbjct: 1427 PQGAPGKPGPDGLRGIPGPVGEQGLPGSPGPDGPPGPMGPPGLPGLKGDSGPKGEKGHPG 1486

Query: 521  LGGRVG-------KGP-GAP-PSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVASAR 571
            L G +G       KG  G P P    GP+       P  P GPP PP     P    +  
Sbjct: 1487 LIGLIGPPGEQGEKGDRGLPGPQGSSGPKGEQGITGPSGPIGPPGPPGLPGPPGPKGAKG 1546

Query: 572  CSLRDPGGGSARIRSRPGRSGGP 594
             S      G A     PG  G P
Sbjct: 1547 SSGPTGPKGEAGHPGPPGPPGPP 1569



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 53/177 (29%), Positives = 65/177 (36%), Gaps = 26/177 (14%)

Query: 387 ARLGQAAAQMRREGWGARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGR 445
           A+  QA A +++     R   G  G+ G+ GP GP      +  PG        G R  +
Sbjct: 541 AQESQAQAILQQARLALRGPAGPMGLTGRPGPVGPPGSGGLKGEPGDVGPQ---GPRGVQ 597

Query: 446 ARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLL---PELPAV 502
                  + G RGR    GA  +P  G+ G      + G A  P          P  P  
Sbjct: 598 GPPGPAGKPGRRGRAGSDGARGMP--GQTGPKGDRGFDGLAGLPGEKGHRGDPGPSGPPG 655

Query: 503 DPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPG-PRPRPDSLSPGEPPGPPTPP 558
            P  D  R  D         G VG      P  LPG P PR   L P  PPGPP PP
Sbjct: 656 PPGDDGERGDD---------GEVG------PRGLPGEPGPR-GLLGPKGPPGPPGPP 696



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 74/316 (23%), Positives = 103/316 (32%), Gaps = 34/316 (10%)

Query: 286  PSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPN 345
            P     AG   P+ + G+     P  PA  +    E+ P G  G       +    P   
Sbjct: 1089 PGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLPGPAGP 1148

Query: 346  FPQSLAEG----LGVSPQAGAR--VGEAREAVTTHERAHLDREGEARARLGQAAAQMRRE 399
                  +G    +G   Q G++   GE      T  +  + + G + A  G+   + ++ 
Sbjct: 1149 VGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTGPQGPIGQPGPSGAD-GEPGPRGQQG 1207

Query: 400  GWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGR 459
             +G +   G RG  G   PGP         PG        GQ             G RG 
Sbjct: 1208 LFGQKGDEGPRGFPGP--PGPVGLQGLPGPPGEKGETGDVGQMG------PPGPPGPRGP 1259

Query: 460  GWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRT 519
               PGA   P G   G+GNP   G       P     P LP        + E     +  
Sbjct: 1260 SGAPGADG-PQGPPGGIGNP---GAVGEKGEPGEAGEPGLPGEGGPPGPKGERGEKGESG 1315

Query: 520  ELGGRVGKGPGAPPSALPGPRPRPDSLS-PGEPPGPPTPPPARALPAAVASARCSLRDPG 578
              G     GP  PP    GP+  P  +  PG+P  P  P PA              +D  
Sbjct: 1316 PSGAAGPPGPKGPPGD-DGPKGSPGPVGFPGDPGPPGEPGPAG-------------QDGP 1361

Query: 579  GGSARIRSRPGRSGGP 594
             G       PG++G P
Sbjct: 1362 PGDKGDDGEPGQTGSP 1377



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 60/218 (27%), Positives = 78/218 (35%), Gaps = 33/218 (15%)

Query: 402  GARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRARA-RTGSQ--VGSR 457
            G     G RG  G  GP G    P  +  PG A      G++  +  A R G Q  VG  
Sbjct: 1084 GPAGSPGERGPAGAAGPIGIPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGLQGPVGLP 1143

Query: 458  GRGWGPGAGRVPSGGRRGVGNPERWG-----GEAAAPRPSRVLLPELPAVDPARD-TRRE 511
            G   GP       G +  +G P + G     GE   P P+    P+ P   P       E
Sbjct: 1144 GPA-GPVGPPGEDGDKGEIGEPGQKGSKGDKGEQGPPGPTG---PQGPIGQPGPSGADGE 1199

Query: 512  PDAAAQRTELGGRVGKGPGAPPS--------ALPGP---RPRPDSLSPGEPPGPPTPPPA 560
            P    Q+   G +  +GP   P          LPGP   +     +    PPGPP P   
Sbjct: 1200 PGPRGQQGLFGQKGDEGPRGFPGPPGPVGLQGLPGPPGEKGETGDVGQMGPPGPPGPRG- 1258

Query: 561  RALPAAVASARCSLRDPGG----GSARIRSRPGRSGGP 594
               P+    A      PGG    G+   +  PG +G P
Sbjct: 1259 ---PSGAPGADGPQGPPGGIGNPGAVGEKGEPGEAGEP 1293



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 60/255 (23%), Positives = 79/255 (30%), Gaps = 56/255 (21%)

Query: 341  SPRPNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDREGEARARLGQAAAQMRREG 400
            +P  + PQ    G+G +P A    GE  EA        L  EG      G+         
Sbjct: 1262 APGADGPQGPPGGIG-NPGAVGEKGEPGEA----GEPGLPGEGGPPGPKGER-------- 1308

Query: 401  WGARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGR 459
             G + + G  G  G  GP GP  D   + +PG        G       A      G +G 
Sbjct: 1309 -GEKGESGPSGAAGPPGPKGPPGDDGPKGSPGPVGFPGDPGPPGEPGPAGQDGPPGDKGD 1367

Query: 460  GWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRT 519
               PG  +  S G  G   P    G+   P P+    PE                     
Sbjct: 1368 DGEPG--QTGSPGPTGEPGPSGPPGKRGPPGPAG---PE--------------------- 1401

Query: 520  ELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVASARCSLRDPGG 579
               GR G+      + L GP  +   + P   PG P P   R +P  V            
Sbjct: 1402 ---GRQGEKGAKGEAGLEGPPGKTGPIGPQGAPGKPGPDGLRGIPGPV------------ 1446

Query: 580  GSARIRSRPGRSGGP 594
            G   +   PG  G P
Sbjct: 1447 GEQGLPGSPGPDGPP 1461



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 26/69 (37%), Positives = 30/69 (43%), Gaps = 9/69 (13%)

Query: 523 GRVGKGPGAP--PSALPGPR----PRPDSLSPGE--PPGPPTPPPARALPAAVAS-ARCS 573
           G + +GP  P  P+ LPGP     P      PGE  PPG P  P A  LP    +     
Sbjct: 464 GMLIEGPPGPEGPAGLPGPPGTMGPTGQVGDPGERGPPGRPGLPGADGLPGPPGTMLMLP 523

Query: 574 LRDPGGGSA 582
            R  GGG A
Sbjct: 524 FRFGGGGDA 532


>gi|98985810 alpha 1 type XI collagen isoform B preproprotein [Homo
            sapiens]
          Length = 1818

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 65/203 (32%), Positives = 77/203 (37%), Gaps = 39/203 (19%)

Query: 402  GARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGR-ARARTGSQVGSRGRG 460
            GA  + G RGV GK GP        +R P         G R  R AR  TG   G +G  
Sbjct: 874  GANGEKGARGVAGKPGP------RGQRGP--------TGPRGSRGARGPTGKP-GPKGTS 918

Query: 461  WGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTE 520
             G G    P  G RG   P+   G    P P        P   P +D    P    QR E
Sbjct: 919  GGDGPPGPP--GERGPQGPQ---GPVGFPGPKG------PPGPPGKDGL--PGHPGQRGE 965

Query: 521  LGGRVGKGPGAPPSALPGPRPRPDSLSPGEP--PGPPTPPPARALPAAVASARCSLRDPG 578
             G +   GP  P   +    P  ++   GE   PGPP PP  + LP A A    +  DPG
Sbjct: 966  TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGA-AGKEGAKGDPG 1024

Query: 579  -------GGSARIRSRPGRSGGP 594
                    G A +R  PG  G P
Sbjct: 1025 PQGISGKDGPAGLRGFPGERGLP 1047



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 59/209 (28%), Positives = 74/209 (35%), Gaps = 27/209 (12%)

Query: 408  GGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRARA-RTGSQ--VGSRGRGWGP 463
            G RG  G  GP G    P  +  PG A      G++  +  A R G Q  VG  G   GP
Sbjct: 1072 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA-GP 1130

Query: 464  GAGRVPSGGRRGVGNPERWG-----GEAAAPRP----SRVLLPELPAVDPARDTRREPDA 514
                   G +  +G P + G     GE   P P      V  P +   D     R +   
Sbjct: 1131 AGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGM 1190

Query: 515  AAQRTELGGRVGKGPGAPPS--ALPGP---RPRPDSLSPGEPPGPPTPPPARALPAAVAS 569
              Q+ + G R   GP  P     LPGP   +     + P  PPGPP P      P     
Sbjct: 1191 FGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG----PQGPNG 1246

Query: 570  ARCSLRDPGG----GSARIRSRPGRSGGP 594
            A      PG     G    +  PG +G P
Sbjct: 1247 ADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1275



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 54/211 (25%), Positives = 72/211 (34%), Gaps = 31/211 (14%)

Query: 390  GQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARAR 449
            G A A+ R+   GA+ + G  G  GK GP     PA +  PG      + G    +    
Sbjct: 1378 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGK--PGPEGLRGIPGPVGEQGLPG 1435

Query: 450  TGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTR 509
               Q G  G    PG   +        G+P   G +     P  + L   P     +  R
Sbjct: 1436 AAGQDGPPGPMGPPGLPGLK-------GDP---GSKGEKGHPGLIGLIGPPGEQGEKGDR 1485

Query: 510  REPDAAAQRTELGGRVGKGPGAP-----PSALPGPR-------------PRPDSLSPGEP 551
              P         G     GP  P     P  LPGP+              + DS  PG P
Sbjct: 1486 GLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPG-P 1544

Query: 552  PGPPTPPPARALPAAVASARCSLRDPGGGSA 582
            PG P PP     P  + S++ + R   G  A
Sbjct: 1545 PGSPGPPGEVIQPLPILSSKKTRRHTEGMQA 1575



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 52/202 (25%), Positives = 63/202 (31%), Gaps = 44/202 (21%)

Query: 402  GARAKLGGRGVCGKCGP----------GPWDDPARRRNPGAAARAKLAGQRAGRARARTG 451
            G R   G  G  G  GP          G   +P    NPG    A + G +  R      
Sbjct: 1237 GPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK--- 1293

Query: 452  SQVGSRGRGWGPGAGRVPSG-GRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRR 510
             + G  G    PGA   P   G +G   P  + G+   P                     
Sbjct: 1294 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPG-------------------- 1333

Query: 511  EPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVASA 570
            EP  A Q   +GG   KG    P   PGP        P    GPP PP  R  P A  + 
Sbjct: 1334 EPGPAGQ-DGVGG--DKGEDGDPGQ-PGPP------GPSGEAGPPGPPGKRGPPGAAGAE 1383

Query: 571  RCSLRDPGGGSARIRSRPGRSG 592
                     G A     PG++G
Sbjct: 1384 GRQGEKGAKGEAGAEGPPGKTG 1405



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 55/228 (24%), Positives = 73/228 (32%), Gaps = 26/228 (11%)

Query: 387 ARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRA 446
           A+  QA A +++     R   G  G+ G+  PGP   P      G +      G R  + 
Sbjct: 523 AQEAQAQAILQQARIALRGPPGPMGLTGR--PGPVGGPGSSGAKGESGDPGPQGPRGVQG 580

Query: 447 RARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAP-----RPSRVLLPELPA 501
                 + G RGR    G   +P  G  G      + G    P     R  R   P+ P 
Sbjct: 581 PPGPTGKPGKRGRPGADGGRGMP--GEPGAKGDRGFDGLPGLPGDKGHRGERG--PQGPP 636

Query: 502 VDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGP------- 554
             P  D  R  D       L G  G      P   PG   +P       PPGP       
Sbjct: 637 GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 696

Query: 555 --PTPPPARALPA--AVASARCSLRDPG----GGSARIRSRPGRSGGP 594
             P PP  +  P    +   +  +  PG     G   +   PG  G P
Sbjct: 697 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 744


>gi|98985808 alpha 1 type XI collagen isoform C preproprotein [Homo
           sapiens]
          Length = 1767

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 65/203 (32%), Positives = 77/203 (37%), Gaps = 39/203 (19%)

Query: 402 GARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGR-ARARTGSQVGSRGRG 460
           GA  + G RGV GK GP        +R P         G R  R AR  TG   G +G  
Sbjct: 823 GANGEKGARGVAGKPGP------RGQRGP--------TGPRGSRGARGPTGKP-GPKGTS 867

Query: 461 WGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTE 520
            G G    P  G RG   P+   G    P P        P   P +D    P    QR E
Sbjct: 868 GGDGPPGPP--GERGPQGPQ---GPVGFPGPKG------PPGPPGKDGL--PGHPGQRGE 914

Query: 521 LGGRVGKGPGAPPSALPGPRPRPDSLSPGEP--PGPPTPPPARALPAAVASARCSLRDPG 578
            G +   GP  P   +    P  ++   GE   PGPP PP  + LP A A    +  DPG
Sbjct: 915 TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGA-AGKEGAKGDPG 973

Query: 579 -------GGSARIRSRPGRSGGP 594
                   G A +R  PG  G P
Sbjct: 974 PQGISGKDGPAGLRGFPGERGLP 996



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 59/209 (28%), Positives = 74/209 (35%), Gaps = 27/209 (12%)

Query: 408  GGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRARA-RTGSQ--VGSRGRGWGP 463
            G RG  G  GP G    P  +  PG A      G++  +  A R G Q  VG  G   GP
Sbjct: 1021 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA-GP 1079

Query: 464  GAGRVPSGGRRGVGNPERWG-----GEAAAPRP----SRVLLPELPAVDPARDTRREPDA 514
                   G +  +G P + G     GE   P P      V  P +   D     R +   
Sbjct: 1080 AGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGM 1139

Query: 515  AAQRTELGGRVGKGPGAPPS--ALPGP---RPRPDSLSPGEPPGPPTPPPARALPAAVAS 569
              Q+ + G R   GP  P     LPGP   +     + P  PPGPP P      P     
Sbjct: 1140 FGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG----PQGPNG 1195

Query: 570  ARCSLRDPGG----GSARIRSRPGRSGGP 594
            A      PG     G    +  PG +G P
Sbjct: 1196 ADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1224



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 54/211 (25%), Positives = 72/211 (34%), Gaps = 31/211 (14%)

Query: 390  GQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARAR 449
            G A A+ R+   GA+ + G  G  GK GP     PA +  PG      + G    +    
Sbjct: 1327 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGK--PGPEGLRGIPGPVGEQGLPG 1384

Query: 450  TGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTR 509
               Q G  G    PG   +        G+P   G +     P  + L   P     +  R
Sbjct: 1385 AAGQDGPPGPMGPPGLPGLK-------GDP---GSKGEKGHPGLIGLIGPPGEQGEKGDR 1434

Query: 510  REPDAAAQRTELGGRVGKGPGAP-----PSALPGPR-------------PRPDSLSPGEP 551
              P         G     GP  P     P  LPGP+              + DS  PG P
Sbjct: 1435 GLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPG-P 1493

Query: 552  PGPPTPPPARALPAAVASARCSLRDPGGGSA 582
            PG P PP     P  + S++ + R   G  A
Sbjct: 1494 PGSPGPPGEVIQPLPILSSKKTRRHTEGMQA 1524



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 52/202 (25%), Positives = 63/202 (31%), Gaps = 44/202 (21%)

Query: 402  GARAKLGGRGVCGKCGP----------GPWDDPARRRNPGAAARAKLAGQRAGRARARTG 451
            G R   G  G  G  GP          G   +P    NPG    A + G +  R      
Sbjct: 1186 GPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK--- 1242

Query: 452  SQVGSRGRGWGPGAGRVPSG-GRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRR 510
             + G  G    PGA   P   G +G   P  + G+   P                     
Sbjct: 1243 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPG-------------------- 1282

Query: 511  EPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVASA 570
            EP  A Q   +GG   KG    P   PGP        P    GPP PP  R  P A  + 
Sbjct: 1283 EPGPAGQ-DGVGG--DKGEDGDPGQ-PGPP------GPSGEAGPPGPPGKRGPPGAAGAE 1332

Query: 571  RCSLRDPGGGSARIRSRPGRSG 592
                     G A     PG++G
Sbjct: 1333 GRQGEKGAKGEAGAEGPPGKTG 1354



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 55/228 (24%), Positives = 73/228 (32%), Gaps = 26/228 (11%)

Query: 387 ARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRA 446
           A+  QA A +++     R   G  G+ G+  PGP   P      G +      G R  + 
Sbjct: 472 AQEAQAQAILQQARIALRGPPGPMGLTGR--PGPVGGPGSSGAKGESGDPGPQGPRGVQG 529

Query: 447 RARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAP-----RPSRVLLPELPA 501
                 + G RGR    G   +P  G  G      + G    P     R  R   P+ P 
Sbjct: 530 PPGPTGKPGKRGRPGADGGRGMP--GEPGAKGDRGFDGLPGLPGDKGHRGERG--PQGPP 585

Query: 502 VDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGP------- 554
             P  D  R  D       L G  G      P   PG   +P       PPGP       
Sbjct: 586 GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 645

Query: 555 --PTPPPARALPA--AVASARCSLRDPG----GGSARIRSRPGRSGGP 594
             P PP  +  P    +   +  +  PG     G   +   PG  G P
Sbjct: 646 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 693


>gi|98985806 alpha 1 type XI collagen isoform A preproprotein [Homo
            sapiens]
          Length = 1806

 Score = 55.5 bits (132), Expect = 1e-07
 Identities = 65/203 (32%), Positives = 77/203 (37%), Gaps = 39/203 (19%)

Query: 402  GARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGR-ARARTGSQVGSRGRG 460
            GA  + G RGV GK GP        +R P         G R  R AR  TG   G +G  
Sbjct: 862  GANGEKGARGVAGKPGP------RGQRGP--------TGPRGSRGARGPTGKP-GPKGTS 906

Query: 461  WGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTE 520
             G G    P  G RG   P+   G    P P        P   P +D    P    QR E
Sbjct: 907  GGDGPPGPP--GERGPQGPQ---GPVGFPGPKG------PPGPPGKDGL--PGHPGQRGE 953

Query: 521  LGGRVGKGPGAPPSALPGPRPRPDSLSPGEP--PGPPTPPPARALPAAVASARCSLRDPG 578
             G +   GP  P   +    P  ++   GE   PGPP PP  + LP A A    +  DPG
Sbjct: 954  TGFQGKTGPPGPGGVVGPQGPTGETGPIGERGHPGPPGPPGEQGLPGA-AGKEGAKGDPG 1012

Query: 579  -------GGSARIRSRPGRSGGP 594
                    G A +R  PG  G P
Sbjct: 1013 PQGISGKDGPAGLRGFPGERGLP 1035



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 59/209 (28%), Positives = 74/209 (35%), Gaps = 27/209 (12%)

Query: 408  GGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRARA-RTGSQ--VGSRGRGWGP 463
            G RG  G  GP G    P  +  PG A      G++  +  A R G Q  VG  G   GP
Sbjct: 1060 GERGSAGTAGPIGLPGRPGPQGPPGPAGEKGAPGEKGPQGPAGRDGVQGPVGLPGPA-GP 1118

Query: 464  GAGRVPSGGRRGVGNPERWG-----GEAAAPRP----SRVLLPELPAVDPARDTRREPDA 514
                   G +  +G P + G     GE   P P      V  P +   D     R +   
Sbjct: 1119 AGSPGEDGDKGEIGEPGQKGSKGDKGENGPPGPPGLQGPVGAPGIAGGDGEPGPRGQQGM 1178

Query: 515  AAQRTELGGRVGKGPGAPPS--ALPGP---RPRPDSLSPGEPPGPPTPPPARALPAAVAS 569
              Q+ + G R   GP  P     LPGP   +     + P  PPGPP P      P     
Sbjct: 1179 FGQKGDEGARGFPGPPGPIGLQGLPGPPGEKGENGDVGPMGPPGPPGPRG----PQGPNG 1234

Query: 570  ARCSLRDPGG----GSARIRSRPGRSGGP 594
            A      PG     G    +  PG +G P
Sbjct: 1235 ADGPQGPPGSVGSVGGVGEKGEPGEAGNP 1263



 Score = 41.6 bits (96), Expect = 0.002
 Identities = 54/211 (25%), Positives = 72/211 (34%), Gaps = 31/211 (14%)

Query: 390  GQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARAR 449
            G A A+ R+   GA+ + G  G  GK GP     PA +  PG      + G    +    
Sbjct: 1366 GAAGAEGRQGEKGAKGEAGAEGPPGKTGPVGPQGPAGK--PGPEGLRGIPGPVGEQGLPG 1423

Query: 450  TGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTR 509
               Q G  G    PG   +        G+P   G +     P  + L   P     +  R
Sbjct: 1424 AAGQDGPPGPMGPPGLPGLK-------GDP---GSKGEKGHPGLIGLIGPPGEQGEKGDR 1473

Query: 510  REPDAAAQRTELGGRVGKGPGAP-----PSALPGPR-------------PRPDSLSPGEP 551
              P         G     GP  P     P  LPGP+              + DS  PG P
Sbjct: 1474 GLPGTQGSPGAKGDGGIPGPAGPLGPPGPPGLPGPQGPKGNKGSTGPAGQKGDSGLPG-P 1532

Query: 552  PGPPTPPPARALPAAVASARCSLRDPGGGSA 582
            PG P PP     P  + S++ + R   G  A
Sbjct: 1533 PGSPGPPGEVIQPLPILSSKKTRRHTEGMQA 1563



 Score = 40.8 bits (94), Expect = 0.004
 Identities = 52/202 (25%), Positives = 63/202 (31%), Gaps = 44/202 (21%)

Query: 402  GARAKLGGRGVCGKCGP----------GPWDDPARRRNPGAAARAKLAGQRAGRARARTG 451
            G R   G  G  G  GP          G   +P    NPG    A + G +  R      
Sbjct: 1225 GPRGPQGPNGADGPQGPPGSVGSVGGVGEKGEPGEAGNPGPPGEAGVGGPKGERGEK--- 1281

Query: 452  SQVGSRGRGWGPGAGRVPSG-GRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRR 510
             + G  G    PGA   P   G +G   P  + G+   P                     
Sbjct: 1282 GEAGPPGAAGPPGAKGPPGDDGPKGNPGPVGFPGDPGPPG-------------------- 1321

Query: 511  EPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVASA 570
            EP  A Q   +GG   KG    P   PGP        P    GPP PP  R  P A  + 
Sbjct: 1322 EPGPAGQ-DGVGG--DKGEDGDPGQ-PGPP------GPSGEAGPPGPPGKRGPPGAAGAE 1371

Query: 571  RCSLRDPGGGSARIRSRPGRSG 592
                     G A     PG++G
Sbjct: 1372 GRQGEKGAKGEAGAEGPPGKTG 1393



 Score = 38.1 bits (87), Expect = 0.023
 Identities = 55/228 (24%), Positives = 73/228 (32%), Gaps = 26/228 (11%)

Query: 387 ARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRA 446
           A+  QA A +++     R   G  G+ G+  PGP   P      G +      G R  + 
Sbjct: 511 AQEAQAQAILQQARIALRGPPGPMGLTGR--PGPVGGPGSSGAKGESGDPGPQGPRGVQG 568

Query: 447 RARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAP-----RPSRVLLPELPA 501
                 + G RGR    G   +P  G  G      + G    P     R  R   P+ P 
Sbjct: 569 PPGPTGKPGKRGRPGADGGRGMP--GEPGAKGDRGFDGLPGLPGDKGHRGERG--PQGPP 624

Query: 502 VDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGP------- 554
             P  D  R  D       L G  G      P   PG   +P       PPGP       
Sbjct: 625 GPPGDDGMRGEDGEIGPRGLPGEAGPRGLLGPRGTPGAPGQPGMAGVDGPPGPKGNMGPQ 684

Query: 555 --PTPPPARALPA--AVASARCSLRDPG----GGSARIRSRPGRSGGP 594
             P PP  +  P    +   +  +  PG     G   +   PG  G P
Sbjct: 685 GEPGPPGQQGNPGPQGLPGPQGPIGPPGEKGPQGKPGLAGLPGADGPP 732


>gi|239748756 PREDICTED: hypothetical protein XP_002346788 [Homo
           sapiens]
          Length = 647

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 105/378 (27%), Positives = 122/378 (32%), Gaps = 84/378 (22%)

Query: 262 RHGGRAAAGLGSQRGAALAGLIYL---------PSAAAAAGRHCPLRLAGQAPRTQPACP 312
           R  GR   G G +R  A   L  L         P+A  A G   PL L GQ     PA  
Sbjct: 142 RSCGREGQGRGGRRRRAADTLFQLGPAWPALPAPAAGRALGTDEPLALRGQCG---PAAR 198

Query: 313 AAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQS-LAEGLGVSPQAGA-RVGEAREA 370
                +Q    PW               +PR + P   LA GL ++P+ GA R G    A
Sbjct: 199 RGCAQEQLRNAPW---------------APRAHSPAGRLALGL-IAPRRGAGRAGAGAAA 242

Query: 371 VTTHERAHLDREGEAR------------------ARLGQAAAQMRREGW--------GAR 404
                R      G  +                  A      A + R G+        GA 
Sbjct: 243 CGRRGRIAAPLSGVVQKASYLRPKNLPRLLSMPSAAARPCGAALPRSGFSGRPRGRGGAA 302

Query: 405 AKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQ-RAGRARARTGSQVGSRGRGWGP 463
           A  G RG    CG G     AR   P  A+   LA + RAG     T      RG     
Sbjct: 303 AGRGSRGEHPACGVGL----ARGTAPQPASTWALAARPRAGGTW--TSRFEAQRGCAHQD 356

Query: 464 GAGRVPSGGRRGVGNPER-WGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELG 522
           G  R   G       P R W       RP R     LP      + +R P  A  R    
Sbjct: 357 GQRRTRDGAGNHASEPARVWSPPPRRQRPRR-----LPRASLQEEPKRRPPCA--RPSGA 409

Query: 523 GRVGKGPGA-------PPSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVASARCSLR 575
           G   +GP A       PP A P  R +     P  P G P      A      SA     
Sbjct: 410 GPAREGPAAWPGGAPTPPHARPTGRRQDPEPGPRAPRGGPASSGWHA-----GSAAGRGW 464

Query: 576 DPGGGSARIRSRPGRSGG 593
           DPGGGS R R R  R  G
Sbjct: 465 DPGGGS-RARRRAARGRG 481


>gi|239742799 PREDICTED: hypothetical protein XP_002342652 [Homo
           sapiens]
          Length = 647

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 105/378 (27%), Positives = 122/378 (32%), Gaps = 84/378 (22%)

Query: 262 RHGGRAAAGLGSQRGAALAGLIYL---------PSAAAAAGRHCPLRLAGQAPRTQPACP 312
           R  GR   G G +R  A   L  L         P+A  A G   PL L GQ     PA  
Sbjct: 142 RSCGREGQGRGGRRRRAADTLFQLGPAWPALPAPAAGRALGTDEPLALRGQCG---PAAR 198

Query: 313 AAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQS-LAEGLGVSPQAGA-RVGEAREA 370
                +Q    PW               +PR + P   LA GL ++P+ GA R G    A
Sbjct: 199 RGCAQEQLRNAPW---------------APRAHSPAGRLALGL-IAPRRGAGRAGAGAAA 242

Query: 371 VTTHERAHLDREGEAR------------------ARLGQAAAQMRREGW--------GAR 404
                R      G  +                  A      A + R G+        GA 
Sbjct: 243 CGRRGRIAAPLSGVVQKASYLRPKNLPRLLSMPSAAARPCGAALPRSGFSGRPRGRGGAA 302

Query: 405 AKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQ-RAGRARARTGSQVGSRGRGWGP 463
           A  G RG    CG G     AR   P  A+   LA + RAG     T      RG     
Sbjct: 303 AGRGSRGEHPACGVGL----ARGTAPQPASTWALAARPRAGGTW--TSRFEAQRGCAHQD 356

Query: 464 GAGRVPSGGRRGVGNPER-WGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELG 522
           G  R   G       P R W       RP R     LP      + +R P  A  R    
Sbjct: 357 GQRRTRDGAGNHASEPARVWSPPPRRQRPRR-----LPRASLQEEPKRRPPCA--RPSGA 409

Query: 523 GRVGKGPGA-------PPSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVASARCSLR 575
           G   +GP A       PP A P  R +     P  P G P      A      SA     
Sbjct: 410 GPAREGPAAWPGGAPTPPHARPTGRRQDPEPGPRAPRGGPASSGWHA-----GSAAGRGW 464

Query: 576 DPGGGSARIRSRPGRSGG 593
           DPGGGS R R R  R  G
Sbjct: 465 DPGGGS-RARRRAARGRG 481


>gi|111118972 collagen, type XI, alpha 2 isoform 2 preproprotein [Homo
            sapiens]
          Length = 1650

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 66/215 (30%), Positives = 77/215 (35%), Gaps = 27/215 (12%)

Query: 402  GARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRA-RARTGSQ--VGSR 457
            G     G RG  G  GP GP   P  +  PGAA    + G++       R G Q  VG  
Sbjct: 926  GPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLP 985

Query: 458  GRGWGPGAGRVPSGGRRGVGNPERWG-----GEAAAPRPSRVLLPELPAVDP-ARDTRRE 511
            G    PG      G +  VG+P + G     GE   P P     P  P   P A     E
Sbjct: 986  GPAGPPGVAG-EDGDKGEVGDPGQKGTKGNKGEHGPPGPPG---PIGPVGQPGAAGADGE 1041

Query: 512  PDAAAQRTELGGRVGKGP---GAPPS-----ALPGPRPRPDSLSPGEPPGPPTPPPARAL 563
            P A   +   G +  +G      PP       LPGP           P GPP PP  R  
Sbjct: 1042 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG- 1100

Query: 564  PAAVASARCSLRDPGG----GSARIRSRPGRSGGP 594
            PA    A      PGG    G    +  PG SG P
Sbjct: 1101 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1135



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 74/278 (26%), Positives = 96/278 (34%), Gaps = 43/278 (15%)

Query: 344 PNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDREGEA--RARLGQAAAQMRREGW 401
           P FP       G S + GAR G + ++    ER      G+   R   G++ A+    G 
Sbjct: 730 PGFP-------GASGEKGAR-GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGD 781

Query: 402 GARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGW 461
           G     G RG+ G  GP  +  P  +  PG   +  L G    R       +VG +G+  
Sbjct: 782 GPHGPPGERGLPGPQGPNGFPGP--KGPPGPPGKDGLPGHPGQRG------EVGFQGKTG 833

Query: 462 GPG----------AGRVPSGGRRGVGNPERWGGEAAAPRPSRVL-------LPELPAVDP 504
            PG          AG     G RG   P    GE   P  +           P  P  D 
Sbjct: 834 PPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDG 893

Query: 505 ARDTRREPDAAAQRTELGG---RVGKGPGAPP--SALPGPRPRPDSLSPGEPPGPPTP-- 557
               R  P         GG   +  +GP  PP  +  PG R    S  P  PPG P P  
Sbjct: 894 PAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG 953

Query: 558 PPARALPAAVASARCSLRDPG-GGSARIRSRPGRSGGP 594
           PP  A    V   +  +   G  G       PG +G P
Sbjct: 954 PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPP 991



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 59/231 (25%), Positives = 75/231 (32%), Gaps = 18/231 (7%)

Query: 380 DREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLA 439
           D+     A+  QA A +++     R   G  G  G+  PGP   P      G +      
Sbjct: 376 DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGR--PGPLGQPGSPGLKGESGDLGPQ 433

Query: 440 GQRAGRARARTGSQVGSRGRGWGPGAGRVPSG----GRRGV-GNPERWGGEAAAPRPSRV 494
           G R  +       + G RGR    GA  +P      G RG  G P   G +         
Sbjct: 434 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ 493

Query: 495 LLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPS--------ALPGPRPRPDSL 546
            LP  P  D  R    E        E G R   GP  PP          + GP+    SL
Sbjct: 494 GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSL 553

Query: 547 SPGEPPGPP---TPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
            P   PGPP     P  + LP    +          G   +   PG  G P
Sbjct: 554 GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPP 604



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 58/212 (27%), Positives = 75/212 (35%), Gaps = 31/212 (14%)

Query: 386  RARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGR 445
            R   G   ++ R+ G GA+   G  G  GK GP     PA +  PG      L G    +
Sbjct: 1234 RGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK--PGPDGLRGLPGSVGQQ 1291

Query: 446  ARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPA 505
             R     Q G  G    PG       G RG       G +     P  + L   P     
Sbjct: 1292 GRPGATGQAGPPGPVGPPGL-----PGLRGDA-----GAKGEKGHPGLIGLIGPPGEQGE 1341

Query: 506  RDTRREP---DAAAQRTELG--GRVGK-GPGAPPSALP---GPRPRPDSLSPG------- 549
            +  R  P    +  Q+ E+G  G  G  GPG PP  LP   GP+    +  PG       
Sbjct: 1342 KGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP-GLPGPAGPKGAKGATGPGGPKGEKG 1400

Query: 550  --EPPGPPTPPPARALPAAVASARCSLRDPGG 579
               PPG P PP     P  +   + + R   G
Sbjct: 1401 VQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDG 1432



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 47/186 (25%), Positives = 58/186 (31%), Gaps = 23/186 (12%)

Query: 402  GARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGR- 459
            GA    G  G  G  GP G   +P    +PG      + G R  R       Q G  G  
Sbjct: 1106 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1165

Query: 460  ------------------GWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPA 501
                              G+    G    GG RG    +   GE   P       P    
Sbjct: 1166 GPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGEN 1225

Query: 502  VDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPAR 561
              P    +R P  A      G + GKG    P A+  P  +   + P  P G P P   R
Sbjct: 1226 GPPGPLGKRGP--AGSPGSEGRQGGKGAKGDPGAIGAP-GKTGPVGPAGPAGKPGPDGLR 1282

Query: 562  ALPAAV 567
             LP +V
Sbjct: 1283 GLPGSV 1288



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 48/167 (28%), Positives = 56/167 (33%), Gaps = 36/167 (21%)

Query: 402 GARAKLGGRGVCGKCGP-------GPWDDPARRRNPGAAA-RAKLAGQRAGRARARTGSQ 453
           G R ++G  G  G+ GP       GP  DP     PG    + KL          R G +
Sbjct: 668 GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP---PGLMGEKGKLGVPGLPGYPGRQGPK 724

Query: 454 VGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPD 513
            GS G    PGA      G RG+       GE     P              R  R    
Sbjct: 725 -GSLGFPGFPGASG--EKGARGLSGKSGPRGERGPTGP--------------RGQRGPRG 767

Query: 514 AAAQRTELGGRVGKGPGAPPS--ALPGPRPRPDSLSPGEPPGPPTPP 558
           A  +    G   G GP  PP    LPGP+       P   PGP  PP
Sbjct: 768 ATGKSGAKGTSGGDGPHGPPGERGLPGPQ------GPNGFPGPKGPP 808



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 56/197 (28%), Positives = 70/197 (35%), Gaps = 39/197 (19%)

Query: 402 GARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGW 461
           G    +G  G+ G   PGP  DP  R  PG          RAG          GS G   
Sbjct: 319 GPAGLIGPPGIQGN--PGPVGDPGERGPPG----------RAGLP--------GSDGAPG 358

Query: 462 GPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTEL 521
            PG   +    R G G  ++    AA    ++ +L +      AR   R P      T  
Sbjct: 359 PPGTS-LMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ------ARLALRGPPGPMGYTGR 411

Query: 522 GGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPP--TPPPARA---LPAAVASARCSLRD 576
            G +G+ PG+     PG +     L P  P GP   T PP +A     A    AR    D
Sbjct: 412 PGPLGQ-PGS-----PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGD 465

Query: 577 PG-GGSARIRSRPGRSG 592
           PG  G       PG  G
Sbjct: 466 PGVKGDRGFDGLPGLPG 482



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 47/175 (26%), Positives = 60/175 (34%), Gaps = 13/175 (7%)

Query: 390 GQAAAQMRREGWGARAKLGGRGVCGKCG----PGPWDDPARRRNPGAAARAKLAGQRAGR 445
           G+A  + R    GAR   G  GV G  G    PG   +   R + GA       G+   R
Sbjct: 446 GKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGER 505

Query: 446 ARARTGSQVGSRGRGWGPGA-GRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDP 504
                  ++G RG     G  G +   G  G+  P    G      P   L P+     P
Sbjct: 506 G---DDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 562

Query: 505 ARD-TRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPP 558
            +  T         +  +G    KGP   P  LPG    P S  P   PG   PP
Sbjct: 563 GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG-LPG---MPGSDGPPGHPGKEGPP 613


>gi|111118968 collagen, type XI, alpha 2 isoform 3 preproprotein [Homo
            sapiens]
          Length = 1629

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 66/215 (30%), Positives = 77/215 (35%), Gaps = 27/215 (12%)

Query: 402  GARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRA-RARTGSQ--VGSR 457
            G     G RG  G  GP GP   P  +  PGAA    + G++       R G Q  VG  
Sbjct: 905  GPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLP 964

Query: 458  GRGWGPGAGRVPSGGRRGVGNPERWG-----GEAAAPRPSRVLLPELPAVDP-ARDTRRE 511
            G    PG      G +  VG+P + G     GE   P P     P  P   P A     E
Sbjct: 965  GPAGPPGVAG-EDGDKGEVGDPGQKGTKGNKGEHGPPGPPG---PIGPVGQPGAAGADGE 1020

Query: 512  PDAAAQRTELGGRVGKGP---GAPPS-----ALPGPRPRPDSLSPGEPPGPPTPPPARAL 563
            P A   +   G +  +G      PP       LPGP           P GPP PP  R  
Sbjct: 1021 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG- 1079

Query: 564  PAAVASARCSLRDPGG----GSARIRSRPGRSGGP 594
            PA    A      PGG    G    +  PG SG P
Sbjct: 1080 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1114



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 74/278 (26%), Positives = 96/278 (34%), Gaps = 43/278 (15%)

Query: 344 PNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDREGEA--RARLGQAAAQMRREGW 401
           P FP       G S + GAR G + ++    ER      G+   R   G++ A+    G 
Sbjct: 709 PGFP-------GASGEKGAR-GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGD 760

Query: 402 GARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGW 461
           G     G RG+ G  GP  +  P  +  PG   +  L G    R       +VG +G+  
Sbjct: 761 GPHGPPGERGLPGPQGPNGFPGP--KGPPGPPGKDGLPGHPGQRG------EVGFQGKTG 812

Query: 462 GPG----------AGRVPSGGRRGVGNPERWGGEAAAPRPSRVL-------LPELPAVDP 504
            PG          AG     G RG   P    GE   P  +           P  P  D 
Sbjct: 813 PPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDG 872

Query: 505 ARDTRREPDAAAQRTELGG---RVGKGPGAPP--SALPGPRPRPDSLSPGEPPGPPTP-- 557
               R  P         GG   +  +GP  PP  +  PG R    S  P  PPG P P  
Sbjct: 873 PAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG 932

Query: 558 PPARALPAAVASARCSLRDPG-GGSARIRSRPGRSGGP 594
           PP  A    V   +  +   G  G       PG +G P
Sbjct: 933 PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPP 970



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 59/231 (25%), Positives = 75/231 (32%), Gaps = 18/231 (7%)

Query: 380 DREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLA 439
           D+     A+  QA A +++     R   G  G  G+  PGP   P      G +      
Sbjct: 355 DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGR--PGPLGQPGSPGLKGESGDLGPQ 412

Query: 440 GQRAGRARARTGSQVGSRGRGWGPGAGRVPSG----GRRGV-GNPERWGGEAAAPRPSRV 494
           G R  +       + G RGR    GA  +P      G RG  G P   G +         
Sbjct: 413 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ 472

Query: 495 LLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPS--------ALPGPRPRPDSL 546
            LP  P  D  R    E        E G R   GP  PP          + GP+    SL
Sbjct: 473 GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSL 532

Query: 547 SPGEPPGPP---TPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
            P   PGPP     P  + LP    +          G   +   PG  G P
Sbjct: 533 GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPP 583



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 58/212 (27%), Positives = 75/212 (35%), Gaps = 31/212 (14%)

Query: 386  RARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGR 445
            R   G   ++ R+ G GA+   G  G  GK GP     PA +  PG      L G    +
Sbjct: 1213 RGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK--PGPDGLRGLPGSVGQQ 1270

Query: 446  ARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPA 505
             R     Q G  G    PG       G RG       G +     P  + L   P     
Sbjct: 1271 GRPGATGQAGPPGPVGPPGL-----PGLRGDA-----GAKGEKGHPGLIGLIGPPGEQGE 1320

Query: 506  RDTRREP---DAAAQRTELG--GRVGK-GPGAPPSALP---GPRPRPDSLSPG------- 549
            +  R  P    +  Q+ E+G  G  G  GPG PP  LP   GP+    +  PG       
Sbjct: 1321 KGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP-GLPGPAGPKGAKGATGPGGPKGEKG 1379

Query: 550  --EPPGPPTPPPARALPAAVASARCSLRDPGG 579
               PPG P PP     P  +   + + R   G
Sbjct: 1380 VQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDG 1411



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 47/186 (25%), Positives = 58/186 (31%), Gaps = 23/186 (12%)

Query: 402  GARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGR- 459
            GA    G  G  G  GP G   +P    +PG      + G R  R       Q G  G  
Sbjct: 1085 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1144

Query: 460  ------------------GWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPA 501
                              G+    G    GG RG    +   GE   P       P    
Sbjct: 1145 GPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGEN 1204

Query: 502  VDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPAR 561
              P    +R P  A      G + GKG    P A+  P  +   + P  P G P P   R
Sbjct: 1205 GPPGPLGKRGP--AGSPGSEGRQGGKGAKGDPGAIGAP-GKTGPVGPAGPAGKPGPDGLR 1261

Query: 562  ALPAAV 567
             LP +V
Sbjct: 1262 GLPGSV 1267



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 48/167 (28%), Positives = 56/167 (33%), Gaps = 36/167 (21%)

Query: 402 GARAKLGGRGVCGKCGP-------GPWDDPARRRNPGAAA-RAKLAGQRAGRARARTGSQ 453
           G R ++G  G  G+ GP       GP  DP     PG    + KL          R G +
Sbjct: 647 GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP---PGLMGEKGKLGVPGLPGYPGRQGPK 703

Query: 454 VGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPD 513
            GS G    PGA      G RG+       GE     P              R  R    
Sbjct: 704 -GSLGFPGFPGASG--EKGARGLSGKSGPRGERGPTGP--------------RGQRGPRG 746

Query: 514 AAAQRTELGGRVGKGPGAPPS--ALPGPRPRPDSLSPGEPPGPPTPP 558
           A  +    G   G GP  PP    LPGP+       P   PGP  PP
Sbjct: 747 ATGKSGAKGTSGGDGPHGPPGERGLPGPQ------GPNGFPGPKGPP 787



 Score = 30.8 bits (68), Expect = 3.7
 Identities = 56/197 (28%), Positives = 70/197 (35%), Gaps = 39/197 (19%)

Query: 402 GARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGW 461
           G    +G  G+ G   PGP  DP  R  PG          RAG          GS G   
Sbjct: 298 GPAGLIGPPGIQGN--PGPVGDPGERGPPG----------RAGLP--------GSDGAPG 337

Query: 462 GPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTEL 521
            PG   +    R G G  ++    AA    ++ +L +      AR   R P      T  
Sbjct: 338 PPGTS-LMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ------ARLALRGPPGPMGYTGR 390

Query: 522 GGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPP--TPPPARA---LPAAVASARCSLRD 576
            G +G+ PG+     PG +     L P  P GP   T PP +A     A    AR    D
Sbjct: 391 PGPLGQ-PGS-----PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGARGMPGD 444

Query: 577 PG-GGSARIRSRPGRSG 592
           PG  G       PG  G
Sbjct: 445 PGVKGDRGFDGLPGLPG 461



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 47/175 (26%), Positives = 60/175 (34%), Gaps = 13/175 (7%)

Query: 390 GQAAAQMRREGWGARAKLGGRGVCGKCG----PGPWDDPARRRNPGAAARAKLAGQRAGR 445
           G+A  + R    GAR   G  GV G  G    PG   +   R + GA       G+   R
Sbjct: 425 GKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGER 484

Query: 446 ARARTGSQVGSRGRGWGPGA-GRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDP 504
                  ++G RG     G  G +   G  G+  P    G      P   L P+     P
Sbjct: 485 G---DDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 541

Query: 505 ARD-TRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPP 558
            +  T         +  +G    KGP   P  LPG    P S  P   PG   PP
Sbjct: 542 GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG-LPG---MPGSDGPPGHPGKEGPP 592


>gi|111118970 collagen, type XI, alpha 2 isoform 1 preproprotein [Homo
            sapiens]
          Length = 1736

 Score = 54.3 bits (129), Expect = 3e-07
 Identities = 66/215 (30%), Positives = 77/215 (35%), Gaps = 27/215 (12%)

Query: 402  GARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRA-RARTGSQ--VGSR 457
            G     G RG  G  GP GP   P  +  PGAA    + G++       R G Q  VG  
Sbjct: 1012 GPAGSPGERGAAGSGGPIGPPGRPGPQGPPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLP 1071

Query: 458  GRGWGPGAGRVPSGGRRGVGNPERWG-----GEAAAPRPSRVLLPELPAVDP-ARDTRRE 511
            G    PG      G +  VG+P + G     GE   P P     P  P   P A     E
Sbjct: 1072 GPAGPPGVAG-EDGDKGEVGDPGQKGTKGNKGEHGPPGPPG---PIGPVGQPGAAGADGE 1127

Query: 512  PDAAAQRTELGGRVGKGP---GAPPS-----ALPGPRPRPDSLSPGEPPGPPTPPPARAL 563
            P A   +   G +  +G      PP       LPGP           P GPP PP  R  
Sbjct: 1128 PGARGPQGHFGAKGDEGTRGFNGPPGPIGLQGLPGPSGEKGETGDVGPMGPPGPPGPRG- 1186

Query: 564  PAAVASARCSLRDPGG----GSARIRSRPGRSGGP 594
            PA    A      PGG    G    +  PG SG P
Sbjct: 1187 PAGPNGADGPQGPPGGVGNLGPPGEKGEPGESGSP 1221



 Score = 46.6 bits (109), Expect = 6e-05
 Identities = 74/278 (26%), Positives = 96/278 (34%), Gaps = 43/278 (15%)

Query: 344  PNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDREGEA--RARLGQAAAQMRREGW 401
            P FP       G S + GAR G + ++    ER      G+   R   G++ A+    G 
Sbjct: 816  PGFP-------GASGEKGAR-GLSGKSGPRGERGPTGPRGQRGPRGATGKSGAKGTSGGD 867

Query: 402  GARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGW 461
            G     G RG+ G  GP  +  P  +  PG   +  L G    R       +VG +G+  
Sbjct: 868  GPHGPPGERGLPGPQGPNGFPGP--KGPPGPPGKDGLPGHPGQRG------EVGFQGKTG 919

Query: 462  GPG----------AGRVPSGGRRGVGNPERWGGEAAAPRPSRVL-------LPELPAVDP 504
             PG          AG     G RG   P    GE   P  +           P  P  D 
Sbjct: 920  PPGPPGVVGPQGAAGETGPMGERGHPGPPGPPGEQGLPGTAGKEGTKGDPGPPGAPGKDG 979

Query: 505  ARDTRREPDAAAQRTELGG---RVGKGPGAPP--SALPGPRPRPDSLSPGEPPGPPTP-- 557
                R  P         GG   +  +GP  PP  +  PG R    S  P  PPG P P  
Sbjct: 980  PAGLRGFPGERGLPGTAGGPGLKGNEGPSGPPGPAGSPGERGAAGSGGPIGPPGRPGPQG 1039

Query: 558  PPARALPAAVASARCSLRDPG-GGSARIRSRPGRSGGP 594
            PP  A    V   +  +   G  G       PG +G P
Sbjct: 1040 PPGAAGEKGVPGEKGPIGPTGRDGVQGPVGLPGPAGPP 1077



 Score = 44.7 bits (104), Expect = 2e-04
 Identities = 59/231 (25%), Positives = 75/231 (32%), Gaps = 18/231 (7%)

Query: 380 DREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLA 439
           D+     A+  QA A +++     R   G  G  G+  PGP   P      G +      
Sbjct: 462 DKGPVVAAQEAQAQAILQQARLALRGPPGPMGYTGR--PGPLGQPGSPGLKGESGDLGPQ 519

Query: 440 GQRAGRARARTGSQVGSRGRGWGPGAGRVPSG----GRRGV-GNPERWGGEAAAPRPSRV 494
           G R  +       + G RGR    GA  +P      G RG  G P   G +         
Sbjct: 520 GPRGPQGLTGPPGKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQ 579

Query: 495 LLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPS--------ALPGPRPRPDSL 546
            LP  P  D  R    E        E G R   GP  PP          + GP+    SL
Sbjct: 580 GLPGPPGEDGERGDDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSL 639

Query: 547 SPGEPPGPP---TPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
            P   PGPP     P  + LP    +          G   +   PG  G P
Sbjct: 640 GPQGEPGPPGQQGTPGTQGLPGPQGAIGPHGEKGPQGKPGLPGMPGSDGPP 690



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 58/212 (27%), Positives = 75/212 (35%), Gaps = 31/212 (14%)

Query: 386  RARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGR 445
            R   G   ++ R+ G GA+   G  G  GK GP     PA +  PG      L G    +
Sbjct: 1320 RGPAGSPGSEGRQGGKGAKGDPGAIGAPGKTGPVGPAGPAGK--PGPDGLRGLPGSVGQQ 1377

Query: 446  ARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPA 505
             R     Q G  G    PG       G RG       G +     P  + L   P     
Sbjct: 1378 GRPGATGQAGPPGPVGPPGL-----PGLRGDA-----GAKGEKGHPGLIGLIGPPGEQGE 1427

Query: 506  RDTRREP---DAAAQRTELG--GRVGK-GPGAPPSALP---GPRPRPDSLSPG------- 549
            +  R  P    +  Q+ E+G  G  G  GPG PP  LP   GP+    +  PG       
Sbjct: 1428 KGDRGLPGPQGSPGQKGEMGIPGASGPIGPGGPP-GLPGPAGPKGAKGATGPGGPKGEKG 1486

Query: 550  --EPPGPPTPPPARALPAAVASARCSLRDPGG 579
               PPG P PP     P  +   + + R   G
Sbjct: 1487 VQGPPGHPGPPGEVIQPLPIQMPKKTRRSVDG 1518



 Score = 37.7 bits (86), Expect = 0.030
 Identities = 47/186 (25%), Positives = 58/186 (31%), Gaps = 23/186 (12%)

Query: 402  GARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGR- 459
            GA    G  G  G  GP G   +P    +PG      + G R  R       Q G  G  
Sbjct: 1192 GADGPQGPPGGVGNLGPPGEKGEPGESGSPGIQGEPGVKGPRGERGEKGESGQPGEPGPP 1251

Query: 460  ------------------GWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPA 501
                              G+    G    GG RG    +   GE   P       P    
Sbjct: 1252 GPKGPTGDDGPKGNPGPVGFPGDPGPPGEGGPRGQDGAKGDRGEDGEPGQPGSPGPTGEN 1311

Query: 502  VDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPAR 561
              P    +R P  A      G + GKG    P A+  P  +   + P  P G P P   R
Sbjct: 1312 GPPGPLGKRGP--AGSPGSEGRQGGKGAKGDPGAIGAP-GKTGPVGPAGPAGKPGPDGLR 1368

Query: 562  ALPAAV 567
             LP +V
Sbjct: 1369 GLPGSV 1374



 Score = 35.0 bits (79), Expect = 0.19
 Identities = 71/262 (27%), Positives = 89/262 (33%), Gaps = 46/262 (17%)

Query: 344 PNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDREGEARARLGQAAAQ---MRREG 400
           P  P     G G   +    +G A  A T H  A        +   G+ A     M  EG
Sbjct: 340 PEGPYDYTYGYGDDYREETELGPALSAETAHSGAAAHGPRGLKGEKGEPAVLEPGMLVEG 399

Query: 401 ----WGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGS 456
                G    +G  G+ G   PGP  DP  R  PG          RAG          GS
Sbjct: 400 PPGPEGPAGLIGPPGIQGN--PGPVGDPGERGPPG----------RAGLP--------GS 439

Query: 457 RGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAA 516
            G    PG   +    R G G  ++    AA    ++ +L +      AR   R P    
Sbjct: 440 DGAPGPPGTS-LMLPFRFGSGGGDKGPVVAAQEAQAQAILQQ------ARLALRGPPGPM 492

Query: 517 QRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPP--TPPPARA---LPAAVASAR 571
             T   G +G+ PG+     PG +     L P  P GP   T PP +A     A    AR
Sbjct: 493 GYTGRPGPLGQ-PGS-----PGLKGESGDLGPQGPRGPQGLTGPPGKAGRRGRAGADGAR 546

Query: 572 CSLRDPG-GGSARIRSRPGRSG 592
               DPG  G       PG  G
Sbjct: 547 GMPGDPGVKGDRGFDGLPGLPG 568



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 48/167 (28%), Positives = 56/167 (33%), Gaps = 36/167 (21%)

Query: 402 GARAKLGGRGVCGKCGP-------GPWDDPARRRNPGAAA-RAKLAGQRAGRARARTGSQ 453
           G R ++G  G  G+ GP       GP  DP     PG    + KL          R G +
Sbjct: 754 GDRGEVGVPGSRGEDGPEGPKGRTGPTGDPGP---PGLMGEKGKLGVPGLPGYPGRQGPK 810

Query: 454 VGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPD 513
            GS G    PGA      G RG+       GE     P              R  R    
Sbjct: 811 -GSLGFPGFPGASG--EKGARGLSGKSGPRGERGPTGP--------------RGQRGPRG 853

Query: 514 AAAQRTELGGRVGKGPGAPPS--ALPGPRPRPDSLSPGEPPGPPTPP 558
           A  +    G   G GP  PP    LPGP+       P   PGP  PP
Sbjct: 854 ATGKSGAKGTSGGDGPHGPPGERGLPGPQ------GPNGFPGPKGPP 894



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 47/175 (26%), Positives = 60/175 (34%), Gaps = 13/175 (7%)

Query: 390 GQAAAQMRREGWGARAKLGGRGVCGKCG----PGPWDDPARRRNPGAAARAKLAGQRAGR 445
           G+A  + R    GAR   G  GV G  G    PG   +   R + GA       G+   R
Sbjct: 532 GKAGRRGRAGADGARGMPGDPGVKGDRGFDGLPGLPGEKGHRGDTGAQGLPGPPGEDGER 591

Query: 446 ARARTGSQVGSRGRGWGPGA-GRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDP 504
                  ++G RG     G  G +   G  G+  P    G      P   L P+     P
Sbjct: 592 G---DDGEIGPRGLPGESGPRGLLGPKGPPGIPGPPGVRGMDGPQGPKGSLGPQGEPGPP 648

Query: 505 ARD-TRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPP 558
            +  T         +  +G    KGP   P  LPG    P S  P   PG   PP
Sbjct: 649 GQQGTPGTQGLPGPQGAIGPHGEKGPQGKPG-LPG---MPGSDGPPGHPGKEGPP 699


>gi|239758013 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 819

 Score = 53.9 bits (128), Expect = 4e-07
 Identities = 84/354 (23%), Positives = 123/354 (34%), Gaps = 44/354 (12%)

Query: 262 RHGGRAAAGLGSQRGAALAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTE 321
           R  G+ AA  GS++    A       +AAA  ++   R AG     Q A  AA    Q  
Sbjct: 124 RRRGQKAAATGSKKPRWRA-----QKSAAAGSKN---RGAG----AQKAAAAAGVKSQGG 171

Query: 322 REPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDR 381
            +P     AG++ +       R    +   +  G   +A +R G+ R       R     
Sbjct: 172 EKPQKAAAAGAKSRSGKKPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPKPA 231

Query: 382 EGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQ 441
            G A++R G      ++   G +A  GG+   GK   G  D   RR+   AA    LAG 
Sbjct: 232 AGGAKSRRGGGKKPQKQRRRGQKAATGGKSRVGK-SRGGGDKKLRRQGQNAA----LAGA 286

Query: 442 RAGRARARTGSQVGSRGRG-------------WGPGAGRVP------------SGGRRGV 476
           +  R  A  G +  ++GRG             WG G G+ P            +G +RG 
Sbjct: 287 KR-RGAATAGEKPAAKGRGGRGPKSLGGQNPRWGRG-GKKPRRRGQKATKAAAAGTKRGG 344

Query: 477 GNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSAL 536
           G  ++        R  +    + P    A     +      +  L     +G G      
Sbjct: 345 GGQQKAAVVGVKSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRW 404

Query: 537 PGPRPRPDSLSPGEPPGPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGR 590
             PR R       +P G  +  P R  P A  S     R  GG   R R +  R
Sbjct: 405 QNPRRRAQKAPAAKPRGGGSKKPRRRGPKAAKSRGGKSRSGGGKKPRRRGQKAR 458



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 61/275 (22%), Positives = 92/275 (33%), Gaps = 28/275 (10%)

Query: 326 GGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDREGEA 385
           G  G G+        +P     +S A  L  +      +G   + +   + A   ++   
Sbjct: 14  GRAGPGAPLGAALARTPVELAAESAAPALSAAAAGVKILGSGDKKLRRQKAAAGGKKARL 73

Query: 386 RARLGQAAAQMRREGWGARAKLGG---RG-------VCGKCGPGPWDDPARRRNPGAAAR 435
           R + G  A +  R+ W   A  GG   RG         G    G      RRR   AAA 
Sbjct: 74  RGQKGAVAGKEARQHWQKAAGAGGAENRGGGEQKAAAAGTKSLGGRGRKPRRRGQKAAA- 132

Query: 436 AKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGR-RGVGNPERWGGEAAAPRPSRV 494
               G +  R RA+  +  GS+ RG G       +G + +G   P++     A  R  + 
Sbjct: 133 ---TGSKKPRWRAQKSAAAGSKNRGAGAQKAAAAAGVKSQGGEKPQKAAAAGAKSRSGK- 188

Query: 495 LLPELPAVDPAR---DTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEP 551
                    P R    +R + D   ++ E   R GK  G        P+P          
Sbjct: 189 --------KPRRRGAKSRGDEDKKGRQREAKSRFGKTRGGRRKKHRRPKPAAGGAKSRRG 240

Query: 552 PG-PPTPPPARALPAAVASARCSLRDPGGGSARIR 585
            G  P     R   AA        +  GGG  ++R
Sbjct: 241 GGKKPQKQRRRGQKAATGGKSRVGKSRGGGDKKLR 275



 Score = 39.7 bits (91), Expect = 0.008
 Identities = 58/223 (26%), Positives = 76/223 (34%), Gaps = 37/223 (16%)

Query: 254 GDLDVQHLRHGGRAAAGLGSQRGAALAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPA 313
           G  D +  R G  AA     +RGAA AG    P+A    GR  P  L GQ PR       
Sbjct: 268 GGGDKKLRRQGQNAALAGAKRRGAATAG--EKPAAKGRGGRG-PKSLGGQNPR------- 317

Query: 314 APRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGARVGEAREAVTT 373
                      WG  G   R +            Q   +      + G    +    V  
Sbjct: 318 -----------WGRGGKKPRRR-----------GQKATKAAAAGTKRGGGGQQKAAVVGV 355

Query: 374 HERAHLDREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGP-WDDPARRRNPGA 432
             R    R G+   R   +AA  +  G G +  L      G     P W +P RR     
Sbjct: 356 KSRKKQRRRGKKPRRQKASAAGAKSRGGGDKKGLREAKRRGDGRKKPRWQNPRRRAQKAP 415

Query: 433 AARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRG 475
           AA+ +  G +  R R    ++  SRG     G G+ P   RRG
Sbjct: 416 AAKPRGGGSKKPRRRGPKAAK--SRGGKSRSGGGKKPR--RRG 454



 Score = 30.4 bits (67), Expect = 4.8
 Identities = 33/115 (28%), Positives = 51/115 (44%), Gaps = 16/115 (13%)

Query: 382 EGEARARLGQAAAQMRREGWGARAK-LGGRGVCGKCGPGPWDDPAR-----RRNPGAAAR 435
           E  A A +GQ  A+ R++    RAK  G  G     G  PW    +     +   G  A+
Sbjct: 672 ESSAAAAVGQ-EAEARKKPRRRRAKSRGDGGQNAAVGINPWQRRGKKPRLGKSRGGGGAK 730

Query: 436 AKLAG----QRAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEA 486
           ++ +G    + +G A++R+G +  +     G GA R     RRG G   R G +A
Sbjct: 731 SRGSGGAKSRGSGGAKSRSGKKAAASKSHGGGGAKR-----RRGGGAKSRSGEKA 780


>gi|111118976 collagen, type II, alpha 1 isoform 1 precursor [Homo
           sapiens]
          Length = 1487

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 91/346 (26%), Positives = 114/346 (32%), Gaps = 49/346 (14%)

Query: 280 AGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHD 339
           AG   LP A    G        G A    PA PA  R +Q    P G +G          
Sbjct: 617 AGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL--------- 667

Query: 340 ESPRPNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDREGEARARLGQAAAQMRRE 399
             P P  P     G G  P      GEA        R      GE R   G    Q  R 
Sbjct: 668 --PGPPGPP----GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE-RGSPGAQGLQGPRG 720

Query: 400 GWGARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRG 458
             G     G +G  G  GP G    P  +  PG    A +AG +  R         G+ G
Sbjct: 721 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 780

Query: 459 RGWGPG-------AGRVPSGGRRG-VGNPERWG-----------GEAAAPRPSRVLLPEL 499
           +  G G        G   + G +G VG P   G           GE   P P+    P  
Sbjct: 781 KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP-- 838

Query: 500 PAVDPARDTRREPDAAAQRTELGGRVGKGP-GAP----PSALPGPRPRPDSLSPGEPPGP 554
           P  D     + E   A Q+ + G    +GP GAP    P+ + GP+    +  P    G 
Sbjct: 839 PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGF 898

Query: 555 P------TPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
           P       PP +   P        S +D   G+      PGR+G P
Sbjct: 899 PGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEP 944



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 56/207 (27%), Positives = 73/207 (35%), Gaps = 30/207 (14%)

Query: 402 GARAKLGGRGVCGKCG-------PGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQV 454
           GA   LG +G  G+ G        GP  +P      GA   A   G+R  R        +
Sbjct: 444 GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 503

Query: 455 GSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDA 514
           G  G    PG    P  G+ G+  P+   GE     PS +  P+    DP R        
Sbjct: 504 GPPGERGAPGNRGFP--GQDGLAGPKGAPGERG---PSGLAGPKGANGDPGRPGEPGLPG 558

Query: 515 AAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVA--SARC 572
           A   T   G  G      PS  PG   R         PGPP P  AR  P  +     + 
Sbjct: 559 ARGLTGRPGDAGPQGKVGPSGAPGEDGR---------PGPPGPQGARGQPGVMGFPGPKG 609

Query: 573 SLRDPG-------GGSARIRSRPGRSG 592
           +  +PG        G+  +R  PG+ G
Sbjct: 610 ANGEPGKAGEKGLPGAPGLRGLPGKDG 636



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 148/599 (24%), Positives = 178/599 (29%), Gaps = 139/599 (23%)

Query: 34   GQAGHPVVGDTGQFERGCARRHRSPRGHRHAVPGPRLQRALGGQAWAGRRQLHGFMLYSG 93
            G+ G P  GD G      A     PRG R   PG R   + G Q   G R L G     G
Sbjct: 675  GEGGKP--GDQGVPGEAGAPGLVGPRGER-GFPGER--GSPGAQGLQGPRGLPGTPGTDG 729

Query: 94   QQRDGHRGGHDVGGRGGGGRLQLVAGALGLGAGVLDHSGLRVAVGRAHLEHEVGAALHDV 153
             +  G  G     G  G   LQ + G  G  AG+    G R  VG    E   G      
Sbjct: 730  PK--GASGPAGPPGAQGPPGLQGMPGERG-AAGIAGPKGDRGDVGEKGPEGAPG------ 780

Query: 154  LDLQEAGRVHDHELLAGRHGEPARVAEGQDLLEAGGRHGAGQLEGALAVAAEQVAEVEAA 213
               ++ GR      L G  G P       +  E G    AG   GA     E+       
Sbjct: 781  ---KDGGRG-----LTGPIGPPGPAGANGEKGEVGPPGPAGSA-GARGAPGER------- 824

Query: 214  GGQHRPVGLEGLA--LDHDGHIAVEAQQALLVQAAQHCVPEVGDLDVQHLRHGGRAAAGL 271
             G+  P G  G A     DG    + +Q    Q      P            G     G 
Sbjct: 825  -GETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP 883

Query: 272  GSQRGA-ALAGLIYLPSAAA---------------------------AAGRHCPLRLAGQ 303
               RGA    G    P AA                            A G   P   AG+
Sbjct: 884  KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 943

Query: 304  APRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGAR 363
                 PA P   + +  +  P G EG              P  PQ LA   G+    G R
Sbjct: 944  PGLQGPAGPPGEKGEPGDDGPSGAEG--------------PPGPQGLAGQRGIVGLPGQR 989

Query: 364  VGEAREAVTTHERAHLDREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGP----G 419
                       ER      G +    G+   Q      GA    G RG  G  GP    G
Sbjct: 990  ----------GERGFPGLPGPS----GEPGKQ------GAPGASGDRGPPGPVGPPGLTG 1029

Query: 420  PWDDPARRRNPGA---AARAKLAGQRAGRARARTGSQVGSRGRGWGPG-AGRV------- 468
            P  +P R  +PGA     R   AG +  R         G+ G    PG AG         
Sbjct: 1030 PAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRG 1089

Query: 469  ---------PSG--GRRGVGNPER-WGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAA 516
                     PSG  G RG+  P+   G +  A  P    L         +     P  + 
Sbjct: 1090 EAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSG 1149

Query: 517  QRTELGGRVGKGPGAPPSAL-----------------PGPRPRPDSLSPGEPPGPPTPP 558
             +   G     GP  PP  +                 PGPR R     P  PPG P PP
Sbjct: 1150 DQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1208



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 57/198 (28%), Positives = 67/198 (33%), Gaps = 14/198 (7%)

Query: 402  GARAKLGGRGVCGKCGPGPW-DDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRG 460
            GAR   G RG  G  GP  +   P     PGA      AGQ+            G+ G  
Sbjct: 816  GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 875

Query: 461  WGPGAGRVPSGGRRGVGNPERWGGEAAAPR---PSRVLLPELPAVDPARDTRREPDAAAQ 517
             GP     P G R   G P   G   AA R   P     P  P   P    +  P  A  
Sbjct: 876  -GPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG-PPGPSGKDGPKGARG 933

Query: 518  RTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVASARCSLRDP 577
             +   GR G+     P+  PG +  P    P    GPP        P  +A  R  +  P
Sbjct: 934  DSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG-------PQGLAGQRGIVGLP 986

Query: 578  G-GGSARIRSRPGRSGGP 594
            G  G       PG SG P
Sbjct: 987  GQRGERGFPGLPGPSGEP 1004



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 64/232 (27%), Positives = 76/232 (32%), Gaps = 29/232 (12%)

Query: 390 GQAAAQMRREGWGARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRA----- 443
           G A A   +   G   + G  GV G  GP GP   P +  + G A +   AG+R      
Sbjct: 213 GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 272

Query: 444 -GRARARTGSQVGSRGRGWGPGA-GRVPSGGRRGVGNPERWGGEAAAPRPS--RVLLPEL 499
             R    T    G +G    PG  G     G  GV       GE  +P P   R L  E 
Sbjct: 273 GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 332

Query: 500 PAVDPA-----RDTRREPDAAAQRTELGGRVGKG-PGAP-------------PSALPGPR 540
               PA     R    +P  A     +G   G G PGAP             P    GPR
Sbjct: 333 GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 392

Query: 541 PRPDSLSPGEPPGPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSG 592
             P +     P G    P    +P A  SA         G    R  PG  G
Sbjct: 393 GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 444



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 40/142 (28%), Positives = 44/142 (30%), Gaps = 28/142 (19%)

Query: 430 PGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGA-GRVPSGGRRGVGNPERWGGEAAA 488
           PG    A   G R  R         G RGR   PG  G     G  G   P   GG  AA
Sbjct: 122 PGPQGPAGEQGPRGDRGDKGEKGAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAA 181

Query: 489 PRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGK-GPGAPPSALPGPRPRPDSLS 547
                                 E    AQ   + G +G  GP  PP     P P+    +
Sbjct: 182 QMAGGF---------------DEKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGN 226

Query: 548 PGEPP-----------GPPTPP 558
           PGEP            GPP PP
Sbjct: 227 PGEPGEPGVSGPMGPRGPPGPP 248



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 29/93 (31%), Positives = 35/93 (37%), Gaps = 22/93 (23%)

Query: 520 ELGGRVGKGPGAPPSALPGPRPR------PDSLSPGEPPGPPTPPPARALPAAVASARCS 573
           E G R  +G      A PGPR R      P +  P  PPGPP PP    L    A+    
Sbjct: 130 EQGPRGDRGDKGEKGA-PGPRGRDGEPGTPGNPGPPGPPGPPGPP---GLGGNFAAQMAG 185

Query: 574 LRDPGGGSARI------------RSRPGRSGGP 594
             D   G A++            R  PG +G P
Sbjct: 186 GFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAP 218


>gi|111118974 collagen, type II, alpha 1 isoform 2 precursor [Homo
           sapiens]
          Length = 1418

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 91/346 (26%), Positives = 114/346 (32%), Gaps = 49/346 (14%)

Query: 280 AGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHD 339
           AG   LP A    G        G A    PA PA  R +Q    P G +G          
Sbjct: 548 AGEKGLPGAPGLRGLPGKDGETGAAGPPGPAGPAGERGEQGAPGPSGFQGL--------- 598

Query: 340 ESPRPNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDREGEARARLGQAAAQMRRE 399
             P P  P     G G  P      GEA        R      GE R   G    Q  R 
Sbjct: 599 --PGPPGPP----GEGGKPGDQGVPGEAGAPGLVGPRGERGFPGE-RGSPGAQGLQGPRG 651

Query: 400 GWGARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRG 458
             G     G +G  G  GP G    P  +  PG    A +AG +  R         G+ G
Sbjct: 652 LPGTPGTDGPKGASGPAGPPGAQGPPGLQGMPGERGAAGIAGPKGDRGDVGEKGPEGAPG 711

Query: 459 RGWGPG-------AGRVPSGGRRG-VGNPERWG-----------GEAAAPRPSRVLLPEL 499
           +  G G        G   + G +G VG P   G           GE   P P+    P  
Sbjct: 712 KDGGRGLTGPIGPPGPAGANGEKGEVGPPGPAGSAGARGAPGERGETGPPGPAGFAGP-- 769

Query: 500 PAVDPARDTRREPDAAAQRTELGGRVGKGP-GAP----PSALPGPRPRPDSLSPGEPPGP 554
           P  D     + E   A Q+ + G    +GP GAP    P+ + GP+    +  P    G 
Sbjct: 770 PGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGPKGARGAQGPPGATGF 829

Query: 555 P------TPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
           P       PP +   P        S +D   G+      PGR+G P
Sbjct: 830 PGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGEP 875



 Score = 48.5 bits (114), Expect = 2e-05
 Identities = 56/207 (27%), Positives = 73/207 (35%), Gaps = 30/207 (14%)

Query: 402 GARAKLGGRGVCGKCG-------PGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQV 454
           GA   LG +G  G+ G        GP  +P      GA   A   G+R  R        +
Sbjct: 375 GATGPLGPKGQTGEPGIAGFKGEQGPKGEPGPAGPQGAPGPAGEEGKRGARGEPGGVGPI 434

Query: 455 GSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDA 514
           G  G    PG    P  G+ G+  P+   GE     PS +  P+    DP R        
Sbjct: 435 GPPGERGAPGNRGFP--GQDGLAGPKGAPGERG---PSGLAGPKGANGDPGRPGEPGLPG 489

Query: 515 AAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVA--SARC 572
           A   T   G  G      PS  PG   R         PGPP P  AR  P  +     + 
Sbjct: 490 ARGLTGRPGDAGPQGKVGPSGAPGEDGR---------PGPPGPQGARGQPGVMGFPGPKG 540

Query: 573 SLRDPG-------GGSARIRSRPGRSG 592
           +  +PG        G+  +R  PG+ G
Sbjct: 541 ANGEPGKAGEKGLPGAPGLRGLPGKDG 567



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 148/599 (24%), Positives = 178/599 (29%), Gaps = 139/599 (23%)

Query: 34   GQAGHPVVGDTGQFERGCARRHRSPRGHRHAVPGPRLQRALGGQAWAGRRQLHGFMLYSG 93
            G+ G P  GD G      A     PRG R   PG R   + G Q   G R L G     G
Sbjct: 606  GEGGKP--GDQGVPGEAGAPGLVGPRGER-GFPGER--GSPGAQGLQGPRGLPGTPGTDG 660

Query: 94   QQRDGHRGGHDVGGRGGGGRLQLVAGALGLGAGVLDHSGLRVAVGRAHLEHEVGAALHDV 153
             +  G  G     G  G   LQ + G  G  AG+    G R  VG    E   G      
Sbjct: 661  PK--GASGPAGPPGAQGPPGLQGMPGERG-AAGIAGPKGDRGDVGEKGPEGAPG------ 711

Query: 154  LDLQEAGRVHDHELLAGRHGEPARVAEGQDLLEAGGRHGAGQLEGALAVAAEQVAEVEAA 213
               ++ GR      L G  G P       +  E G    AG   GA     E+       
Sbjct: 712  ---KDGGRG-----LTGPIGPPGPAGANGEKGEVGPPGPAGSA-GARGAPGER------- 755

Query: 214  GGQHRPVGLEGLA--LDHDGHIAVEAQQALLVQAAQHCVPEVGDLDVQHLRHGGRAAAGL 271
             G+  P G  G A     DG    + +Q    Q      P            G     G 
Sbjct: 756  -GETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQGPTGVTGP 814

Query: 272  GSQRGA-ALAGLIYLPSAAA---------------------------AAGRHCPLRLAGQ 303
               RGA    G    P AA                            A G   P   AG+
Sbjct: 815  KGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPGPPGPSGKDGPKGARGDSGPPGRAGE 874

Query: 304  APRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGAR 363
                 PA P   + +  +  P G EG              P  PQ LA   G+    G R
Sbjct: 875  PGLQGPAGPPGEKGEPGDDGPSGAEG--------------PPGPQGLAGQRGIVGLPGQR 920

Query: 364  VGEAREAVTTHERAHLDREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGP----G 419
                       ER      G +    G+   Q      GA    G RG  G  GP    G
Sbjct: 921  ----------GERGFPGLPGPS----GEPGKQ------GAPGASGDRGPPGPVGPPGLTG 960

Query: 420  PWDDPARRRNPGA---AARAKLAGQRAGRARARTGSQVGSRGRGWGPG-AGRV------- 468
            P  +P R  +PGA     R   AG +  R         G+ G    PG AG         
Sbjct: 961  PAGEPGREGSPGADGPPGRDGAAGVKGDRGETGAVGAPGAPGPPGSPGPAGPTGKQGDRG 1020

Query: 469  ---------PSG--GRRGVGNPER-WGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAA 516
                     PSG  G RG+  P+   G +  A  P    L         +     P  + 
Sbjct: 1021 EAGAQGPMGPSGPAGARGIQGPQGPRGDKGEAGEPGERGLKGHRGFTGLQGLPGPPGPSG 1080

Query: 517  QRTELGGRVGKGPGAPPSAL-----------------PGPRPRPDSLSPGEPPGPPTPP 558
             +   G     GP  PP  +                 PGPR R     P  PPG P PP
Sbjct: 1081 DQGASGPAGPSGPRGPPGPVGPSGKDGANGIPGPIGPPGPRGRSGETGPAGPPGNPGPP 1139



 Score = 46.2 bits (108), Expect = 8e-05
 Identities = 57/198 (28%), Positives = 67/198 (33%), Gaps = 14/198 (7%)

Query: 402 GARAKLGGRGVCGKCGPGPW-DDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRG 460
           GAR   G RG  G  GP  +   P     PGA      AGQ+            G+ G  
Sbjct: 747 GARGAPGERGETGPPGPAGFAGPPGADGQPGAKGEQGEAGQKGDAGAPGPQGPSGAPGPQ 806

Query: 461 WGPGAGRVPSGGRRGVGNPERWGGEAAAPR---PSRVLLPELPAVDPARDTRREPDAAAQ 517
            GP     P G R   G P   G   AA R   P     P  P   P    +  P  A  
Sbjct: 807 -GPTGVTGPKGARGAQGPPGATGFPGAAGRVGPPGSNGNPGPPG-PPGPSGKDGPKGARG 864

Query: 518 RTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVASARCSLRDP 577
            +   GR G+     P+  PG +  P    P    GPP        P  +A  R  +  P
Sbjct: 865 DSGPPGRAGEPGLQGPAGPPGEKGEPGDDGPSGAEGPPG-------PQGLAGQRGIVGLP 917

Query: 578 G-GGSARIRSRPGRSGGP 594
           G  G       PG SG P
Sbjct: 918 GQRGERGFPGLPGPSGEP 935



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 64/232 (27%), Positives = 76/232 (32%), Gaps = 29/232 (12%)

Query: 390 GQAAAQMRREGWGARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRA----- 443
           G A A   +   G   + G  GV G  GP GP   P +  + G A +   AG+R      
Sbjct: 144 GPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPPGKPGDDGEAGKPGKAGERGPPGPQ 203

Query: 444 -GRARARTGSQVGSRGRGWGPGA-GRVPSGGRRGVGNPERWGGEAAAPRPS--RVLLPEL 499
             R    T    G +G    PG  G     G  GV       GE  +P P   R L  E 
Sbjct: 204 GARGFPGTPGLPGVKGHRGYPGLDGAKGEAGAPGVKGESGSPGENGSPGPMGPRGLPGER 263

Query: 500 PAVDPA-----RDTRREPDAAAQRTELGGRVGKG-PGAP-------------PSALPGPR 540
               PA     R    +P  A     +G   G G PGAP             P    GPR
Sbjct: 264 GRTGPAGAAGARGNDGQPGPAGPPGPVGPAGGPGFPGAPGAKGEAGPTGARGPEGAQGPR 323

Query: 541 PRPDSLSPGEPPGPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSG 592
             P +     P G    P    +P A  SA         G    R  PG  G
Sbjct: 324 GEPGTPGSPGPAGASGNPGTDGIPGAKGSAGAPGIAGAPGFPGPRGPPGPQG 375



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 51/180 (28%), Positives = 60/180 (33%), Gaps = 32/180 (17%)

Query: 393 AAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNP-GAAARAKLAGQRAGRARARTG 451
           AA +R +G   R   G +G  G+  PG   D    + P G    A   G R  R      
Sbjct: 18  AAVLRCQGQDVRQP-GPKGQKGE--PGDIKDIVGPKGPPGPQGPAGEQGPRGDRGDKGEK 74

Query: 452 SQVGSRGRGWGPGA-GRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRR 510
              G RGR   PG  G     G  G   P   GG  AA                      
Sbjct: 75  GAPGPRGRDGEPGTPGNPGPPGPPGPPGPPGLGGNFAAQMAGGF---------------D 119

Query: 511 EPDAAAQRTELGGRVGK-GPGAPPSALPGPRPRPDSLSPGEPP-----------GPPTPP 558
           E    AQ   + G +G  GP  PP     P P+    +PGEP            GPP PP
Sbjct: 120 EKAGGAQLGVMQGPMGPMGPRGPPGPAGAPGPQGFQGNPGEPGEPGVSGPMGPRGPPGPP 179



 Score = 31.2 bits (69), Expect = 2.8
 Identities = 29/93 (31%), Positives = 35/93 (37%), Gaps = 22/93 (23%)

Query: 520 ELGGRVGKGPGAPPSALPGPRPR------PDSLSPGEPPGPPTPPPARALPAAVASARCS 573
           E G R  +G      A PGPR R      P +  P  PPGPP PP    L    A+    
Sbjct: 61  EQGPRGDRGDKGEKGA-PGPRGRDGEPGTPGNPGPPGPPGPPGPP---GLGGNFAAQMAG 116

Query: 574 LRDPGGGSARI------------RSRPGRSGGP 594
             D   G A++            R  PG +G P
Sbjct: 117 GFDEKAGGAQLGVMQGPMGPMGPRGPPGPAGAP 149


>gi|113416879 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 175

 Score = 53.5 bits (127), Expect = 5e-07
 Identities = 58/175 (33%), Positives = 64/175 (36%), Gaps = 28/175 (16%)

Query: 381 REGEARARLGQAAAQMRRE----GWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARA 436
           R+G AR R     +  RR     G G R     R       P P ++P  R  P  AAR 
Sbjct: 9   RQGRARGRPHSQVSLARRAPLMFGPGLRDPPPPR----PAPPRPGEEPGNRHPPPPAART 64

Query: 437 KLAGQRAGRARARTGSQVGSRGRG-WGPGAGRVPSGGRRGVGNPER---WG----GEAAA 488
                  G  RAR  S      RG W    GR  +        PER   W     G AAA
Sbjct: 65  -----HPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAA 119

Query: 489 PRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRP 543
           P P R  L   P   P  +  R P A      L G  G    APPS  P PR RP
Sbjct: 120 PAPGRDALRLPPPPPPPPERPRLPPAG-----LAG--GPADSAPPSPAPAPRSRP 167



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 52/172 (30%), Positives = 63/172 (36%), Gaps = 18/172 (10%)

Query: 437 KLAGQRAGRARARTGSQVGSRGRG---WGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSR 493
           K +G+R GRAR R  SQV    R    +GPG  R P   R     P    G    P P+ 
Sbjct: 4   KASGRRQGRARGRPHSQVSLARRAPLMFGPGL-RDPPPPRPAPPRPGEEPGNRHPPPPAA 62

Query: 494 VLLP---ELPAVDPARDTRREPDAAA---QRTELGGRVGKGPGAP------PSALPGPRP 541
              P         PA    R P  AA   QR + G    +           P +   P P
Sbjct: 63  RTHPGSCRARCPSPAAGGLRGPWTAAPGRQRADEGAAAARPERQRVWARRLPGSAAAPAP 122

Query: 542 RPDSLSPGEPPGPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGG 593
             D+L    PP PP PP    LP A  +   +   P   +   RSRP    G
Sbjct: 123 GRDALRL--PPPPPPPPERPRLPPAGLAGGPADSAPPSPAPAPRSRPAPRPG 172


>gi|239750574 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1297

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 172/640 (26%), Positives = 205/640 (32%), Gaps = 174/640 (27%)

Query: 34  GQAGHPVVGDTGQFERGCA---------------RRHRSPRGHRHAVPGPRLQRALGGQA 78
           GQAG P+ G      R  A               RRH   RG R A  GP     L G  
Sbjct: 416 GQAGQPLQGQARGPHRPAALAQEALRAAAARPHGRRHYRVRGLRGA--GPEGAGRLAGP- 472

Query: 79  WAGRRQLHGFMLYSGQQRDGHRGGHD----------VGGRGGGGR----------LQLVA 118
           W G R L   +L    Q   H G H+          VGG  G G+           +L A
Sbjct: 473 WRGLR-LQTLLL----QDAPHGGAHEHVLVAVPATGVGGLVGAGQGAVAAAGNAPERLPA 527

Query: 119 GALGLGAGV-LDHSGLRVAVGRAH------------LEHEVGAALHDVLDLQEAGRVHDH 165
           G  G G  V     G RVA G               L  ++G A H  +     G +   
Sbjct: 528 GVQGCGEEVGRGARGDRVAGGHVEVVPVGQQLAICMLHGQLGTAPHAHVPTVLGGALGGR 587

Query: 166 ELLAG---RHGEPARVAEGQDLLEAGGRHGAGQLEGALAVAAEQVAEVEAAGGQH----- 217
             L     R   PAR   G        RHG G   G      + +     AGG H     
Sbjct: 588 AGLVAAPARRECPARRRGGCWPRRPRRRHGGGG--GGGGPGLQDLLGGGHAGGAHGHVVV 645

Query: 218 -----RPVGLEGLALDHDGHIAVEAQQALLVQAAQHCVPEVGDLDVQ---------HLRH 263
                 P   EG A  H GH+AV   Q   V A     P   DLDV          HL  
Sbjct: 646 APAAAAPTAREGRAGRH-GHVAVVCPQ---VAAG---APVGADLDVSVVLWVGVVGHLGR 698

Query: 264 G---GRAAAGLGSQRGAALAGLIYLPSAAAAAGRHCPL---RLAGQAPRTQPACPAAPRM 317
           G   GRA A   ++ G    G +++       G H PL   R  G  P  QP+     R+
Sbjct: 699 GRGAGRAEAARAAREGGPHQG-VFIQRGRGGLG-HRPLPGWRGQGVGPLAQPSVQVLGRV 756

Query: 318 QQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGARVGEAREAVTTHERA 377
               R+P  G                     ++A+G    P  G    E   A     R 
Sbjct: 757 P---RDPAVGAA-------------------TVAQG----PVHGHVPVELTAAAAVSGRG 790

Query: 378 HLDREGEARARLGQAAAQMRREGWGARAKLGGR--GVCGKCGPGPWDDPARRRNPGAAAR 435
            L R+G    R+   AA+  +  W     + G   GV G             R  GAAA 
Sbjct: 791 RL-RDG--LGRVASVAAEGAQVAWAGAVLVQGHEAGVAGGA-----------RGGGAAAG 836

Query: 436 AKLAGQ----------RAGRAR--ARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWG 483
             LAG           RAGR R  AR  +  G +G G G G  RV  G   G    +R  
Sbjct: 837 GPLAGAVVQRMRQRRVRAGRRRVGARAVAAAGRQGAGAGGGGRRVRHGHGHGAAVLQR-- 894

Query: 484 GEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRP 543
                               P R  R    AAA     G R  +G    P A   P  R 
Sbjct: 895 -------------------APCRQQRHLAPAAAAAAAQGVRAAQGRAHRPGAQGAPSHRH 935

Query: 544 DSLSPGEPPGPPTPPPARALPAAVASARCSL-RDPGGGSA 582
               PG          A AL      AR +L R  GGG A
Sbjct: 936 ---RPGARGRRSRRRAAVALAGGAHPARAALGRRRGGGQA 972



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 124/472 (26%), Positives = 156/472 (33%), Gaps = 90/472 (19%)

Query: 56  RSPRGHRHAVPGPRLQRALGG---------------QAWAGRRQLHGFMLYS----GQQR 96
           R PR       G RLQ + GG                A+  R   HG  + +    G+ R
Sbjct: 204 RGPRPALRCQRGRRLQLSWGGGRLVAPSRADTHAALAAFPERDIFHGGRVVALGVVGEGR 263

Query: 97  DGHRGGHDVGGRGGG-----GRLQLVAGALGLGAGVLDHSGLRVAVGRAHLEHEVGAALH 151
            GH G    GG G G       L++ A  LG   GV   +GL+  +   HL HE    LH
Sbjct: 264 -GHGGDRRGGGEGLGTVAAAAPLRVCADDLGAAVGVRGLAGLQEGLDSRHLLHE-AQPLH 321

Query: 152 DVLDLQEAGRVHDHELLAGRHGEPARVAEGQDLLEAGGRHGAGQLEGALAVAAEQVAEVE 211
                + AG      L  GR           D L  GG H    L G + +   +     
Sbjct: 322 ---ARRRAGHAGSFWLRGGR-----------DRLRRGGGHTKSHL-GVVTIVPGR--RGR 364

Query: 212 AAGGQHRPVGLEGLALDHDGHIAVEAQQALLVQAAQHCVPEVGDLDVQHLRHGGRAAAGL 271
           AAGGQ R            G      QQ    +  +   P +  +DV  L      A GL
Sbjct: 365 AAGGQER------------GGRGRRRQQGR--RGRRQAGPGLAKVDVDVL----AGALGL 406

Query: 272 GSQRGAALAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTE-REPWGGEGA 330
             Q     AG    P    A G H P  LA +A R   A P   R  +       G EGA
Sbjct: 407 RWQWVLVHAGQAGQPLQGQARGPHRPAALAQEALRAAAARPHGRRHYRVRGLRGAGPEGA 466

Query: 331 GS-----RFKRLH----DESPRPNFPQSL---AEGLGVSPQAGARVGEAREAVTTHERAH 378
           G      R  RL      ++P     + +       GV    GA  G    A    ER  
Sbjct: 467 GRLAGPWRGLRLQTLLLQDAPHGGAHEHVLVAVPATGVGGLVGAGQGAVAAAGNAPERLP 526

Query: 379 LDREGEARARLGQAAAQMRREGWGARAKLGGR--GVC---GKCGPGPWDDPARRRNPGAA 433
              +G     +G+ A   R  G        G+   +C   G+ G  P             
Sbjct: 527 AGVQG-CGEEVGRGARGDRVAGGHVEVVPVGQQLAICMLHGQLGTAPHAHVPTVLGGALG 585

Query: 434 ARAKLAGQRAGR---ARARTG-------SQVGSRGRGWGPGAGRVPSGGRRG 475
            RA L    A R   AR R G        + G  G G GPG   +  GG  G
Sbjct: 586 GRAGLVAAPARRECPARRRGGCWPRRPRRRHGGGGGGGGPGLQDLLGGGHAG 637



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 61/203 (30%), Positives = 75/203 (36%), Gaps = 48/203 (23%)

Query: 59   RGHRHAVPGPRLQRALGGQAWAGR-------RQLHGFMLYSGQQRDGHRG----GHDVGG 107
            +GH   V G     A GG A AG        +++    + +G++R G R     G    G
Sbjct: 818  QGHEAGVAGG----ARGGGAAAGGPLAGAVVQRMRQRRVRAGRRRVGARAVAAAGRQGAG 873

Query: 108  RGGGGRLQLVAGALGLGAGVLDHS------------------GLRVAVGRAHLEHEVGAA 149
             GGGGR   V    G GA VL  +                  G+R A GRAH     GA 
Sbjct: 874  AGGGGRR--VRHGHGHGAAVLQRAPCRQQRHLAPAAAAAAAQGVRAAQGRAHRPGAQGAP 931

Query: 150  LHDVLDLQEAGRVHDHELLAGRHG-EPARVAEGQDLLEAGGRHGAGQLEGALAVAAEQVA 208
             H         R      +A   G  PAR A G+       R G GQ     AV A    
Sbjct: 932  SHRHRPGARGRRSRRRAAVALAGGAHPARAALGR-------RRGGGQ-----AVGARAAH 979

Query: 209  EVEAAGGQHRPVGLEGLALDHDG 231
            +   AGGQ   V +   A D DG
Sbjct: 980  QARLAGGQVDQVVVAARAGDADG 1002


>gi|169205732 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 1297

 Score = 52.8 bits (125), Expect = 9e-07
 Identities = 172/640 (26%), Positives = 205/640 (32%), Gaps = 174/640 (27%)

Query: 34  GQAGHPVVGDTGQFERGCA---------------RRHRSPRGHRHAVPGPRLQRALGGQA 78
           GQAG P+ G      R  A               RRH   RG R A  GP     L G  
Sbjct: 416 GQAGQPLQGQARGPHRPAALAQEALRAAAARPHGRRHYRVRGLRGA--GPEGAGRLAGP- 472

Query: 79  WAGRRQLHGFMLYSGQQRDGHRGGHD----------VGGRGGGGR----------LQLVA 118
           W G R L   +L    Q   H G H+          VGG  G G+           +L A
Sbjct: 473 WRGLR-LQTLLL----QDAPHGGAHEHVLVAVPATGVGGLVGAGQGAVAAAGNAPERLPA 527

Query: 119 GALGLGAGV-LDHSGLRVAVGRAH------------LEHEVGAALHDVLDLQEAGRVHDH 165
           G  G G  V     G RVA G               L  ++G A H  +     G +   
Sbjct: 528 GVQGCGEEVGRGARGDRVAGGHVEVVPVGQQLAICMLHGQLGTAPHAHVPTVLGGALGGR 587

Query: 166 ELLAG---RHGEPARVAEGQDLLEAGGRHGAGQLEGALAVAAEQVAEVEAAGGQH----- 217
             L     R   PAR   G        RHG G   G      + +     AGG H     
Sbjct: 588 AGLVAAPARRECPARRRGGCWPRRPRRRHGGGG--GGGGPGLQDLLGGGHAGGAHGHVVV 645

Query: 218 -----RPVGLEGLALDHDGHIAVEAQQALLVQAAQHCVPEVGDLDVQ---------HLRH 263
                 P   EG A  H GH+AV   Q   V A     P   DLDV          HL  
Sbjct: 646 APAAAAPTAREGRAGRH-GHVAVVCPQ---VAAG---APVGADLDVSVVLWVGVVGHLGR 698

Query: 264 G---GRAAAGLGSQRGAALAGLIYLPSAAAAAGRHCPL---RLAGQAPRTQPACPAAPRM 317
           G   GRA A   ++ G    G +++       G H PL   R  G  P  QP+     R+
Sbjct: 699 GRGAGRAEAARAAREGGPHQG-VFIQRGRGGLG-HRPLPGWRGQGVGPLAQPSVQVLGRV 756

Query: 318 QQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGARVGEAREAVTTHERA 377
               R+P  G                     ++A+G    P  G    E   A     R 
Sbjct: 757 P---RDPAVGAA-------------------TVAQG----PVHGHVPVELTAAAAVSGRG 790

Query: 378 HLDREGEARARLGQAAAQMRREGWGARAKLGGR--GVCGKCGPGPWDDPARRRNPGAAAR 435
            L R+G    R+   AA+  +  W     + G   GV G             R  GAAA 
Sbjct: 791 RL-RDG--LGRVASVAAEGAQVAWAGAVLVQGHEAGVAGGA-----------RGGGAAAG 836

Query: 436 AKLAGQ----------RAGRAR--ARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWG 483
             LAG           RAGR R  AR  +  G +G G G G  RV  G   G    +R  
Sbjct: 837 GPLAGAVVQRMRQRRVRAGRRRVGARAVAAAGRQGAGAGGGGRRVRHGHGHGAAVLQR-- 894

Query: 484 GEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRP 543
                               P R  R    AAA     G R  +G    P A   P  R 
Sbjct: 895 -------------------APCRQQRHLAPAAAAAAAQGVRAAQGRAHRPGAQGAPSHRH 935

Query: 544 DSLSPGEPPGPPTPPPARALPAAVASARCSL-RDPGGGSA 582
               PG          A AL      AR +L R  GGG A
Sbjct: 936 ---RPGARGRRSRRRAAVALAGGAHPARAALGRRRGGGQA 972



 Score = 45.1 bits (105), Expect = 2e-04
 Identities = 124/472 (26%), Positives = 156/472 (33%), Gaps = 90/472 (19%)

Query: 56  RSPRGHRHAVPGPRLQRALGG---------------QAWAGRRQLHGFMLYS----GQQR 96
           R PR       G RLQ + GG                A+  R   HG  + +    G+ R
Sbjct: 204 RGPRPALRCQRGRRLQLSWGGGRLVAPSRADTHAALAAFPERDIFHGGRVVALGVVGEGR 263

Query: 97  DGHRGGHDVGGRGGG-----GRLQLVAGALGLGAGVLDHSGLRVAVGRAHLEHEVGAALH 151
            GH G    GG G G       L++ A  LG   GV   +GL+  +   HL HE    LH
Sbjct: 264 -GHGGDRRGGGEGLGTVAAAAPLRVCADDLGAAVGVRGLAGLQEGLDSRHLLHE-AQPLH 321

Query: 152 DVLDLQEAGRVHDHELLAGRHGEPARVAEGQDLLEAGGRHGAGQLEGALAVAAEQVAEVE 211
                + AG      L  GR           D L  GG H    L G + +   +     
Sbjct: 322 ---ARRRAGHAGSFWLRGGR-----------DRLRRGGGHTKSHL-GVVTIVPGR--RGR 364

Query: 212 AAGGQHRPVGLEGLALDHDGHIAVEAQQALLVQAAQHCVPEVGDLDVQHLRHGGRAAAGL 271
           AAGGQ R            G      QQ    +  +   P +  +DV  L      A GL
Sbjct: 365 AAGGQER------------GGRGRRRQQGR--RGRRQAGPGLAKVDVDVL----AGALGL 406

Query: 272 GSQRGAALAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTE-REPWGGEGA 330
             Q     AG    P    A G H P  LA +A R   A P   R  +       G EGA
Sbjct: 407 RWQWVLVHAGQAGQPLQGQARGPHRPAALAQEALRAAAARPHGRRHYRVRGLRGAGPEGA 466

Query: 331 GS-----RFKRLH----DESPRPNFPQSL---AEGLGVSPQAGARVGEAREAVTTHERAH 378
           G      R  RL      ++P     + +       GV    GA  G    A    ER  
Sbjct: 467 GRLAGPWRGLRLQTLLLQDAPHGGAHEHVLVAVPATGVGGLVGAGQGAVAAAGNAPERLP 526

Query: 379 LDREGEARARLGQAAAQMRREGWGARAKLGGR--GVC---GKCGPGPWDDPARRRNPGAA 433
              +G     +G+ A   R  G        G+   +C   G+ G  P             
Sbjct: 527 AGVQG-CGEEVGRGARGDRVAGGHVEVVPVGQQLAICMLHGQLGTAPHAHVPTVLGGALG 585

Query: 434 ARAKLAGQRAGR---ARARTG-------SQVGSRGRGWGPGAGRVPSGGRRG 475
            RA L    A R   AR R G        + G  G G GPG   +  GG  G
Sbjct: 586 GRAGLVAAPARRECPARRRGGCWPRRPRRRHGGGGGGGGPGLQDLLGGGHAG 637



 Score = 41.2 bits (95), Expect = 0.003
 Identities = 61/203 (30%), Positives = 75/203 (36%), Gaps = 48/203 (23%)

Query: 59   RGHRHAVPGPRLQRALGGQAWAGR-------RQLHGFMLYSGQQRDGHRG----GHDVGG 107
            +GH   V G     A GG A AG        +++    + +G++R G R     G    G
Sbjct: 818  QGHEAGVAGG----ARGGGAAAGGPLAGAVVQRMRQRRVRAGRRRVGARAVAAAGRQGAG 873

Query: 108  RGGGGRLQLVAGALGLGAGVLDHS------------------GLRVAVGRAHLEHEVGAA 149
             GGGGR   V    G GA VL  +                  G+R A GRAH     GA 
Sbjct: 874  AGGGGRR--VRHGHGHGAAVLQRAPCRQQRHLAPAAAAAAAQGVRAAQGRAHRPGAQGAP 931

Query: 150  LHDVLDLQEAGRVHDHELLAGRHG-EPARVAEGQDLLEAGGRHGAGQLEGALAVAAEQVA 208
             H         R      +A   G  PAR A G+       R G GQ     AV A    
Sbjct: 932  SHRHRPGARGRRSRRRAAVALAGGAHPARAALGR-------RRGGGQ-----AVGARAAH 979

Query: 209  EVEAAGGQHRPVGLEGLALDHDG 231
            +   AGGQ   V +   A D DG
Sbjct: 980  QARLAGGQVDQVVVAARAGDADG 1002


>gi|91208420 bassoon protein [Homo sapiens]
          Length = 3926

 Score = 52.4 bits (124), Expect = 1e-06
 Identities = 88/359 (24%), Positives = 122/359 (33%), Gaps = 49/359 (13%)

Query: 223  EGLALDHDGHIAVEAQQAL-LVQAAQHCVPEVGDLDVQHLRH-GGRAAAGLGSQRGAAL- 279
            EG  LD D H  V   +A  L Q       +  D      RH GG A +    +RG A  
Sbjct: 3557 EGYILD-DSHCVVSDSEAYHLGQEETDWFDKPRDARSDRFRHHGGHAVSSSSQKRGPARH 3615

Query: 280  ----------AGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTEREPWGGEG 329
                       GL   P      GRH        A   +         + T  EP G   
Sbjct: 3616 SYHDYDEPPEEGL--WPHDEGGPGRHA------SAKEHRHGDHGRHSGRHTGEEP-GRRA 3666

Query: 330  AGSRFKRLHDESPRPNFPQSLAEGLGVSPQAG----ARVGEAREAVTTHERAHLDREGEA 385
            A    + L     RP+   S A  +    Q G    A   +   A + +  A   ++G  
Sbjct: 3667 AKPHARDLGRHEARPHSQPSSAPAMPKKGQPGYPSSAEYSQPSRASSAYHHASDSKKGSR 3726

Query: 386  RARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDD--PARRRNPGAAARAKLAGQRA 443
            +A  G AA Q + E   A+ +L GR    +  PGP     P+ R+ P            +
Sbjct: 3727 QAHSGPAALQSKAEPQ-AQPQLQGR----QAAPGPQQSQSPSSRQIP------------S 3769

Query: 444  GRARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLP---ELP 500
            G A  +  +Q   +G G  P    +     +    P   G   AA +P+    P      
Sbjct: 3770 GAASRQPQTQQQQQGLGLQPPQQALTQARLQQQSQPTTRGSAPAASQPAGKPQPGPSTAT 3829

Query: 501  AVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPP 559
               PA   R E    ++ T    + G+ P A P+  PGP        PG  PG P   P
Sbjct: 3830 GPQPAGPPRAEQTNGSKGTAKAPQQGRAPQAQPAPGPGPAGVKAGARPGGTPGAPAGQP 3888



 Score = 43.1 bits (100), Expect = 7e-04
 Identities = 43/166 (25%), Positives = 59/166 (35%), Gaps = 18/166 (10%)

Query: 417 GPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRGV 476
           GPGP   P   + P A A     GQ      AR+ +     G G GPG G  P    R +
Sbjct: 24  GPGPGPGPGAGKPPSAPAGG---GQLPAAGAARSTAVPPVPGPGPGPGPGPGPGSTSRRL 80

Query: 477 GNPERWGGEAAAPRPSRVLLPELPAVDPARDTR------REPDAAAQRTELGGRVGKGPG 530
              E  G + AA    +      P  +  R+TR      +E D   +  ++  R  +  G
Sbjct: 81  DPKEPLGNQRAASPTPKQASATTPGHESPRETRAQGPAGQEADGPRRTLQVDSRTQRS-G 139

Query: 531 APPSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVASARCSLRD 576
             PS  P     P S        P + P    LP++     C   D
Sbjct: 140 RSPSVSPDRGSTPTS--------PYSVPQIAPLPSSTLCPICKTSD 177



 Score = 36.6 bits (83), Expect = 0.067
 Identities = 33/117 (28%), Positives = 48/117 (41%), Gaps = 13/117 (11%)

Query: 488 APRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPG------APPSALPGPR- 540
           APR         PA+ PA    ++P     +    G  G  PG      A  +++PGP  
Sbjct: 233 APRSKSQQQLHSPALSPAHSPAKQPLGKPDQERSRGPGGPQPGSRQAETARATSVPGPAQ 292

Query: 541 ----PRPDSLSPGEPPGPPTPPPARAL-PAAVASARCSLRDPGGGSARIRSRPGRSG 592
               P    +SP +PP P  P  A    PA  A A+ +   P G  A  +++ G +G
Sbjct: 293 AAAPPEVGRVSP-QPPQPTKPSTAEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTG 348



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 28/75 (37%), Positives = 31/75 (41%), Gaps = 9/75 (12%)

Query: 521 LGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVASARCSLRD-PGG 579
           L G  G GP  P  A PGP P P    PG    P  P     LPAA A+   ++   PG 
Sbjct: 7   LEGGAGDGPLPPGGAGPGPGPGP---GPGAGKPPSAPAGGGQLPAAGAARSTAVPPVPGP 63

Query: 580 GSARIRSRPGRSGGP 594
           G       PG   GP
Sbjct: 64  GPG-----PGPGPGP 73



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 45/148 (30%), Positives = 51/148 (34%), Gaps = 41/148 (27%)

Query: 458 GRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQ 517
           G G GPG G  P     G G P       +AP        +LPA   AR T   P     
Sbjct: 20  GAGPGPGPGPGP-----GAGKP------PSAPAGG----GQLPAAGAARSTAVPP----- 59

Query: 518 RTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPG-----PPTPPPARA-LPAAVASAR 571
                     GPG  P   PGP      L P EP G      PTP  A A  P   +   
Sbjct: 60  --------VPGPGPGPGPGPGPGSTSRRLDPKEPLGNQRAASPTPKQASATTPGHESPRE 111

Query: 572 CSLRDPGGGSA-------RIRSRPGRSG 592
              + P G  A       ++ SR  RSG
Sbjct: 112 TRAQGPAGQEADGPRRTLQVDSRTQRSG 139



 Score = 32.0 bits (71), Expect = 1.7
 Identities = 41/149 (27%), Positives = 54/149 (36%), Gaps = 15/149 (10%)

Query: 425 ARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGG 484
           A  R P   A AK A        A   +Q G  G+ +G GA  +          PE    
Sbjct: 315 AEPRPPAGEAPAKSATAVPAGLGATEQTQEGLTGKLFGLGASLLTQASTLMSVQPE--AD 372

Query: 485 EAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPD 544
               P PS+   P++   D +++   +P        LG   G GP       PG R  P 
Sbjct: 373 TQGQPAPSKGT-PKIVFNDASKEAGPKP--------LGSGPGPGPAPGAKTEPGARMGPG 423

Query: 545 SLSPGEPP---GPPTPPPARALPAAVASA 570
           S  PG  P   G  +P   RA   A + A
Sbjct: 424 S-GPGALPKTGGTTSPKHGRAEHQAASKA 451



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 54/215 (25%), Positives = 78/215 (36%), Gaps = 34/215 (15%)

Query: 364  VGEAREAVTTHERAHLDREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDD 423
            V   R  +  H  +  D + +A A    AAA +R     A + +G + +   C      D
Sbjct: 2626 VRRRRSRLPRHSDSGSDSKHDATASSSSAAATVR-----AMSSVGIQTI-SDCSVQTEPD 2679

Query: 424  PARRRNPG----AAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNP 479
               R +P     AA   K+   R   A  +TG       RG        P G  +GV  P
Sbjct: 2680 QLPRVSPAIHITAATDPKVEIVRYISAPEKTG-------RGESLACQTEPDGQAQGVAGP 2732

Query: 480  ERWGGEAAAPRPSRVLLPELPAVDP---ARDTRREPDAAAQRTELGGRVGKGPGAPPSAL 536
            +  G  A +P      LP +  V P    R  +++PD           +G     PP +L
Sbjct: 2733 QLVGPTAISP-----YLPGIQIVTPGPLGRFEKKKPDPL--------EIGYQAHLPPESL 2779

Query: 537  PGPRPRPDSLSPGEPPGPPTP-PPARALPAAVASA 570
                 R    SP     P +P  P R L  + AS+
Sbjct: 2780 SQLVSRQPPKSPQVLYSPVSPLSPHRLLDTSFASS 2814


>gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens]
          Length = 1464

 Score = 52.0 bits (123), Expect = 2e-06
 Identities = 152/596 (25%), Positives = 189/596 (31%), Gaps = 76/596 (12%)

Query: 10   PAGSTSTDILYGLCGHLLDAGDEGGQAGHPVVGDTGQFERGCARRHRSPRGHR--HAVPG 67
            PAGS     L G  G   +AG  G Q    V GD G      AR  R   G R     PG
Sbjct: 636  PAGSPGFQGLPGPAGPPGEAGKPGEQG---VPGDLGAPGPSGARGERGFPGERGVQGPPG 692

Query: 68   PRLQRALGGQAWAGRRQLHGFMLYSGQQRDGHRGGHDVGGRGGGGRLQLVAGALGLGAGV 127
            P           AG R  +G     G + D   G     G  G   LQ + G  G  AG+
Sbjct: 693  P-----------AGPRGANGAPGNDGAKGDA--GAPGAPGSQGAPGLQGMPGERG-AAGL 738

Query: 128  LDHSGLRVAVGRAHLEHEVGAALHDVLDLQEAGRVHDHELLAGRHGEPARVAEGQDLLEA 187
                G R   G    +   G         ++  R      L G  G P       D  E+
Sbjct: 739  PGPKGDRGDAGPKGADGSPG---------KDGVRG-----LTGPIGPPGPAGAPGDKGES 784

Query: 188  GGRHGAGQLEGALAVAAEQVAEVEAAGGQHRPVGLEGL--ALDHDGHIAVEAQQALLVQA 245
            G    AG      A             G   P G +G   A    G    +        A
Sbjct: 785  GPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPA 844

Query: 246  AQHCVP-EVGDLDVQHLRHGGRAAAGLGSQRG-AALAGLIYLPSAAAAAGRHCPLRLAGQ 303
                 P  +G++     + G R +AG     G    AG +  P  +  AG   P   AG+
Sbjct: 845  GPAGPPGPIGNVGAPGAK-GARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGK 903

Query: 304  APRTQPACPAAPRMQQTEREPWGGEG-AGSRFKRLHDE---SPRPNFPQSLAEGLGVSPQ 359
                 P     P  +  E  P G  G AG +     D    +P    PQ +A   GV   
Sbjct: 904  EGGKGPRGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGL 963

Query: 360  AGARVGEAREAVTTHERAHLDREGEARAR-------------LGQAAAQMRREGW----- 401
             G R GE              ++G + A              L     +  REG      
Sbjct: 964  PGQR-GERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGAEG 1022

Query: 402  --GARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRG 458
              G     G +G  G+ GP GP   P     PG    A  +G R     A     VG  G
Sbjct: 1023 SPGRDGSPGAKGDRGETGPAGPPGAPGAPGAPGPVGPAGKSGDRGETGPAGPAGPVGPVG 1082

Query: 459  RGWGPGAGRVPSG--------GRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRR 510
               GP   + P G        G RG+     + G    P P      + P+        R
Sbjct: 1083 AR-GPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPR 1141

Query: 511  EPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARALPAA 566
             P  +A      G  G  PG  P   PGPR R     P  PPGPP PP     P+A
Sbjct: 1142 GPPGSAGAPGKDGLNGL-PG--PIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSA 1194



 Score = 50.8 bits (120), Expect = 3e-06
 Identities = 88/344 (25%), Positives = 106/344 (30%), Gaps = 63/344 (18%)

Query: 290 AAAGRHCPLRLAGQAPRTQPACPAAPRMQQTEREPW--GGEGAGSRFKRLHDESPRPNFP 347
           +  G   P  +    PR  P  P AP  Q  +  P   G  GA           PR    
Sbjct: 171 STGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPM------GPR---- 220

Query: 348 QSLAEGLGVSPQAGARVGEAREAVTTHERAHLDREGEARARLGQAAAQMRREGWGARAKL 407
                G    P      GEA +     ER     +G AR   G A     +   G     
Sbjct: 221 -----GPPGPPGKNGDDGEAGKPGRPGERGPPGPQG-ARGLPGTAGLPGMKGHRGFSGLD 274

Query: 408 GGRGVCGKCGP----------------GPWDDPARRRNPGAAARAKLAGQRAGRARARTG 451
           G +G  G  GP                GP   P  R  PGA   A   G       A   
Sbjct: 275 GAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPP 334

Query: 452 SQVGSRGRGWGPGA----GRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARD 507
              G  G    PGA    G     G RG   P+   GE   P P+       PA +P  D
Sbjct: 335 GPTGPAGPPGFPGAVGAKGEAGPQGPRGSEGPQGVRGEPGPPGPAGA---AGPAGNPGAD 391

Query: 508 TRREPDAAAQRTELGGRVG----KGPGAPPSALPGPRPRPDSLSPGEP--------PGPP 555
            +     A     + G  G    +GP  P      P P+ +S  PG P         G P
Sbjct: 392 GQPGAKGANGAPGIAGAPGFPGARGPSGPQGPGGPPGPKGNSGEPGAPGSKGDTGAKGEP 451

Query: 556 TP-----PPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
            P     PP    PA     R +  +P  G   +   PG  GGP
Sbjct: 452 GPVGVQGPPG---PAGEEGKRGARGEP--GPTGLPGPPGERGGP 490



 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 61/230 (26%), Positives = 71/230 (30%), Gaps = 39/230 (16%)

Query: 402 GARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRG 460
           G+  K G RG+ G  GP GP   P  +   G +  A   G R            G  G  
Sbjct: 755 GSPGKDGVRGLTGPIGPPGPAGAPGDKGESGPSGPAGPTGARGAPGDRGEPGPPGPAGFA 814

Query: 461 WGPGAGRVPSG-------GRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPD 513
             PGA   P         G +G   P    G A  P P   +    P    AR +   P 
Sbjct: 815 GPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPAGPPGPIGNV--GAPGAKGARGSAGPPG 872

Query: 514 AAAQRTELG-----------------GRVGKGPGAPPSALPGPRPRPDSLSPGEPPGP-- 554
           A       G                 G  GK  G  P    GP  RP  + P  PPGP  
Sbjct: 873 ATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGPRGETGPAGRPGEVGPPGPPGPAG 932

Query: 555 ---------PTPPPARALPAAVASARCSLRDPG-GGSARIRSRPGRSGGP 594
                    P   P    P  +A  R  +  PG  G       PG SG P
Sbjct: 933 EKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEP 982



 Score = 47.4 bits (111), Expect = 4e-05
 Identities = 95/350 (27%), Positives = 114/350 (32%), Gaps = 64/350 (18%)

Query: 264 GGRAAAGLGSQRGAALAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTERE 323
           G + AAG   + G    G+   P A   AG+       G+A    P  PA P  ++ E+ 
Sbjct: 584 GPKGAAGEPGKAGER--GVPGPPGAVGPAGKD------GEAGAQGPPGPAGPAGERGEQG 635

Query: 324 PWGGEGAGSRFKRLHDESPRPNFP-----QSLAEGLGVSPQAGARVGEAREAVTTHERAH 378
           P G  G    F+ L   +  P        Q +   LG    +GAR           ER  
Sbjct: 636 PAGSPG----FQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGAR----------GERGF 681

Query: 379 LDREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCG-PGPWDDPARRRNPGAAARAK 437
               G      G       R   GA    G +G  G  G PG    P  +  PG    A 
Sbjct: 682 PGERGVQ----GPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAG 737

Query: 438 LAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLP 497
           L G +  R  A      G +G    PG       G RG+  P    G A AP       P
Sbjct: 738 LPGPKGDRGDA------GPKGADGSPG-----KDGVRGLTGPIGPPGPAGAPGDKGESGP 786

Query: 498 ELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSA--LPGPRPRPDSL--------- 546
             PA            A   R E G     G   PP A   PG +  P            
Sbjct: 787 SGPA-----GPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPP 841

Query: 547 SPGEPPGPPTPPPARALPAAVASARCSLRDPGG----GSARIRSRPGRSG 592
            P  P GPP P      P A   AR S   PG     G+A     PG SG
Sbjct: 842 GPAGPAGPPGPIGNVGAPGA-KGARGSAGPPGATGFPGAAGRVGPPGPSG 890



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 91/346 (26%), Positives = 110/346 (31%), Gaps = 42/346 (12%)

Query: 272 GSQRGAALAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQ-----QTEREPWG 326
           G+     +AG    P A   +G   P    G  P+     P AP  +     + E  P G
Sbjct: 398 GANGAPGIAGAPGFPGARGPSGPQGPGGPPG--PKGNSGEPGAPGSKGDTGAKGEPGPVG 455

Query: 327 GEG----AGSRFKRLHDESPRPNF---PQSLAEGLGVSPQAGAR-----VGEAREAVTTH 374
            +G    AG   KR     P P     P     G G     GA       G A E  +  
Sbjct: 456 VQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPG 515

Query: 375 ERAHLDREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDD-PARRRNPGAA 433
                   GEA  R G+A     +   G+    G  G  G  GP   D  P     PGA 
Sbjct: 516 PAGPKGSPGEA-GRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGAR 574

Query: 434 ARAKLAGQRAGRARARTGSQVGSRGRGWGPGA----GRVPSGGRRGVGNPERWGGEAAAP 489
            +A + G    +  A    + G RG    PGA    G+    G +G   P    GE    
Sbjct: 575 GQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQ 634

Query: 490 RPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAP-PSALPGPRPRPDSLSP 548
            P+       P           P  A +  E G  V    GAP PS   G R  P     
Sbjct: 635 GPAGS-----PGFQGLPGPAGPPGEAGKPGEQG--VPGDLGAPGPSGARGERGFPGERGV 687

Query: 549 GEPPGPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
             PPGP  P  A   P           D   G A     PG  G P
Sbjct: 688 QGPPGPAGPRGANGAPG---------NDGAKGDAGAPGAPGSQGAP 724



 Score = 45.8 bits (107), Expect = 1e-04
 Identities = 93/348 (26%), Positives = 110/348 (31%), Gaps = 65/348 (18%)

Query: 264  GGRAAAGLGSQRG----AALAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQQ 319
            G R AAGL   +G    A   G    P      G   P+          P  PA     +
Sbjct: 731  GERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIG---------PPGPAGAPGDK 781

Query: 320  TEREPWGGEG-AGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAH 378
             E  P G  G  G+R        P P  P   A   G   Q GA+ GE  +A    +   
Sbjct: 782  GESGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAK-GEPGDAGAKGDAGP 840

Query: 379  LDREGEAR-----ARLGQAAAQMRREGWGARAKLGGRGVCGKCGP-GPWDDPARRRNPGA 432
                G A        +G   A+  R   G     G  G  G+ GP GP  +      PG 
Sbjct: 841  PGPAGPAGPPGPIGNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGP 900

Query: 433  AARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPS 492
            A +    G R     A    +VG  G   GP   +   G     G P   G +  A +  
Sbjct: 901  AGKEGGKGPRGETGPAGRPGEVGPPGPP-GPAGEKGSPGADGPAGAPGTPGPQGIAGQRG 959

Query: 493  RVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSP---- 548
             V LP                   QR E G      PG     LPGP   P    P    
Sbjct: 960  VVGLP------------------GQRGERGF-----PG-----LPGPSGEPGKQGPSGAS 991

Query: 549  GE--PPGPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
            GE  PPGP  PP     P    S R        G+      PGR G P
Sbjct: 992  GERGPPGPMGPPGLAGPPG--ESGR-------EGAPGAEGSPGRDGSP 1030



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 88/352 (25%), Positives = 106/352 (30%), Gaps = 76/352 (21%)

Query: 264  GGRAAAGLGSQRGAA-LAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTER 322
            G   A G    RG+A   G    P AA   G   P   AG      P  P  P  ++  +
Sbjct: 854  GNVGAPGAKGARGSAGPPGATGFPGAAGRVGPPGPSGNAG------PPGPPGPAGKEGGK 907

Query: 323  EPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDRE 382
             P G  G   R   +    P P  P       G    AGA      + +   +R  +   
Sbjct: 908  GPRGETGPAGRPGEVGP--PGPPGPAGEKGSPGADGPAGAPGTPGPQGIAG-QRGVVGLP 964

Query: 383  GEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQ 441
            G+     G+          G   K G  G  G+ GP GP   P     PG + R    G 
Sbjct: 965  GQR----GERGFPGLPGPSGEPGKQGPSGASGERGPPGPMGPPGLAGPPGESGREGAPGA 1020

Query: 442  RAGRARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPA 501
                         GS GR   PGA      G  G   P    G   AP P          
Sbjct: 1021 E------------GSPGRDGSPGA--KGDRGETGPAGPPGAPGAPGAPGP---------- 1056

Query: 502  VDPARDT--RREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGE--------- 550
            V PA  +  R E   A     +G    +GP  P        PR D    GE         
Sbjct: 1057 VGPAGKSGDRGETGPAGPAGPVGPVGARGPAGPQG------PRGDKGETGEQGDRGIKGH 1110

Query: 551  --------PPGPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
                    PPGPP  P  +    A             G A  R  PG +G P
Sbjct: 1111 RGFSGLQGPPGPPGSPGEQGPSGA------------SGPAGPRGPPGSAGAP 1150



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 41/139 (29%), Positives = 45/139 (32%), Gaps = 9/139 (6%)

Query: 462 GPGAGRVPSGGRRGVGNPERWG--GEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRT 519
           GP     P G R   G P R G  G+   P P     P  P   P       P  +    
Sbjct: 112 GPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPG---PPGPPGPPGLGGNFAPQLSYGYD 168

Query: 520 E--LGGRVGKGPGAP--PSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVASARCSLR 575
           E   GG    GP  P  P  LPGP   P       PPG P  P A              +
Sbjct: 169 EKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGK 228

Query: 576 DPGGGSARIRSRPGRSGGP 594
           +   G A    RPG  G P
Sbjct: 229 NGDDGEAGKPGRPGERGPP 247


>gi|156071470 hyperpolarization activated cyclic nucleotide-gated
           potassium channel 2 [Homo sapiens]
          Length = 889

 Score = 51.6 bits (122), Expect = 2e-06
 Identities = 35/88 (39%), Positives = 39/88 (44%), Gaps = 24/88 (27%)

Query: 522 GGRVGKGPGAPPSALPGPRPRPDSLSPGE---PPGPPTPPP------------ARALPAA 566
           GGR G+ PGA P+  PGP P P    P +   PP PP PPP            A ALP  
Sbjct: 7   GGRPGESPGATPA--PGPPPPPPPAPPQQQPPPPPPPAPPPGPGPAPPQHPPRAEALPPE 64

Query: 567 VASARCSLRDPGGGSARIRSRPGRSGGP 594
            A       D GG   R+RSR    G P
Sbjct: 65  AA-------DEGGPRGRLRSRDSSCGRP 85



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 32/95 (33%), Positives = 36/95 (37%), Gaps = 31/95 (32%)

Query: 517 QRTELGGRVGKGPGAPP-----SALPG-------------PRPRPDSLSPGE-------P 551
           Q+ ELG RVG  P  PP     SA+                RP    L+ G        P
Sbjct: 703 QQAELGQRVGLFPPPPPPPQVTSAIATLQQAAAMSFCPQVARPLVGPLALGSPRLVRRPP 762

Query: 552 PGP------PTPPPARALPAAVASARCSLRDPGGG 580
           PGP      P PPP  + P A AS R     P GG
Sbjct: 763 PGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGG 797



 Score = 31.6 bits (70), Expect = 2.2
 Identities = 31/107 (28%), Positives = 36/107 (33%), Gaps = 11/107 (10%)

Query: 463 PGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVL----LPELPAVDPARDTRREPDAAAQR 518
           P  G  P+    G   P    G  A+PR  R      LP  P   PA   RR   A+   
Sbjct: 761 PPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAAPLAGPALPARRLSRASRPL 820

Query: 519 TELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARALPA 565
           +         P  P  A PGP       S   P   PTP    A P+
Sbjct: 821 S------ASQPSLPHGA-PGPAASTRPASSSTPRLGPTPAARAAAPS 860



 Score = 30.0 bits (66), Expect = 6.3
 Identities = 17/44 (38%), Positives = 19/44 (43%), Gaps = 2/44 (4%)

Query: 525 VGKGPGAPPSALPGPRPRPDSLSPGEPPGP--PTPPPARALPAA 566
           V + P  P  A   P P P +  PG P  P  P   P   LPAA
Sbjct: 758 VRRPPPGPAPAAASPGPPPPASPPGAPASPRAPRTSPYGGLPAA 801


>gi|48762934 alpha 2 type I collagen [Homo sapiens]
          Length = 1366

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 147/638 (23%), Positives = 189/638 (29%), Gaps = 103/638 (16%)

Query: 8   PQPAGSTSTDILYGLCGHLLDAGDEG--GQAGHP-VVGDTGQFERGCARRHRSPRGHRHA 64
           P P G+       GL G    AG +G  G  G P   G  G          R P G   +
Sbjct: 330 PGPVGAAGATGARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGS 389

Query: 65  V--PGPR-LQRALGGQAWAGRRQLHGFMLYSGQQRD----GHRGGHDVGGRGGGGRLQLV 117
              PGP  L+ + G +   G     G M   G +      G RG +   GR G   L   
Sbjct: 390 AGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRPGEPGLMGP 449

Query: 118 AGALGLGAGVLDHSGLRVAVGRAHLEHEVGAALHDVLDLQEAGRVHDHELLAGRHGEPAR 177
            G  G   G +  +G    VG   ++   G                     AG  GEP  
Sbjct: 450 RGLPG-SPGNIGPAGKEGPVGLPGIDGRPGPIGP-----------------AGARGEPGN 491

Query: 178 VAEGQDLLEAGGRHGAGQLEGALAVAAEQVAEVEAAGGQHRPVGLEGLALDHDGHIAVEA 237
           +         G     G    A    A      +   G   P G +G             
Sbjct: 492 IGFPGPKGPTGDPGKNGDKGHAGLAGARGAPGPDGNNGAQGPPGPQG------------- 538

Query: 238 QQALLVQAAQHCVPEVGDLDVQHLRHGGRAAAGLGSQRGAALAGLIYLPSAAAAAGRHCP 297
                VQ  +      G    Q L      A  +G      L G   LP  A   G   P
Sbjct: 539 -----VQGGKGEQGPPGPPGFQGLPGPSGPAGEVGKPGERGLHGEFGLPGPAGPRGERGP 593

Query: 298 LRLAGQAPRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVS 357
               G++    P  P   R       P G +G       +    P  + P  L    G +
Sbjct: 594 ---PGESGAAGPTGPIGSRGPSGPPGPDGNKGEPGVVGAVGTAGP--SGPSGLPGERGAA 648

Query: 358 PQAGARVGEAREAVTTHERAHLDREGE--------------ARARLGQAAAQMRREGWGA 403
              G + GE  E     E  +  R+G               A    G+A A       G 
Sbjct: 649 GIPGGK-GEKGEPGLRGEIGNPGRDGARGAPGAVGAPGPAGATGDRGEAGAAGPAGPAGP 707

Query: 404 RAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRG--RGW 461
           R   G RG  G  GP  +  PA     GAA +    G+R  +        VG  G     
Sbjct: 708 RGSPGERGEVGPAGPNGFAGPA-----GAAGQPGAKGERGAKGPKGENGVVGPTGPVGAA 762

Query: 462 GPGAGRVPSG--GRRGVGNPERW------GGEAAAPRPSRVLLPELPAVDPARDTRREPD 513
           GP     P G  G RG G P          G    P PS +  P  P     ++  R P 
Sbjct: 763 GPAGPNGPPGPAGSRGDGGPPGMTGFPGAAGRTGPPGPSGISGPPGPPGPAGKEGLRGP- 821

Query: 514 AAAQRTELG--GRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTP------PPARALPA 565
               R + G  GR G+     P    G +          PPG P P      P    LP 
Sbjct: 822 ----RGDQGPVGRTGEVGAVGPPGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPG 877

Query: 566 A-----VASARCSLRDPG----GGSARIRSRPGRSGGP 594
           +     +     ++ +PG     G    R  PG  G P
Sbjct: 878 SRGERGLPGVAGAVGEPGPLGIAGPPGARGPPGAVGSP 915



 Score = 47.0 bits (110), Expect = 5e-05
 Identities = 70/274 (25%), Positives = 91/274 (33%), Gaps = 53/274 (19%)

Query: 347 PQSLAEGLGVSPQAGAR--VGEAREAVTTHERAHLDREGEARARLGQAAAQMRREGWGAR 404
           P+ +   +G +   GAR  VGE   A +  E  +   +GE     G A  Q      G  
Sbjct: 326 PRGIPGPVGAAGATGARGLVGEPGPAGSKGESGN---KGEP----GSAGPQGPPGPSGEE 378

Query: 405 AKLGGRGVCGKCGP----GPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRG 460
            K G  G  G  GP    G    P  R  PGA  RA + G    R  +      G  G  
Sbjct: 379 GKRGPNGEAGSAGPPGPPGLRGSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDA 438

Query: 461 WGPG-------------AGRVPSGGRRGV-------GNPERWGGEAAAPRPSRVLL--PE 498
             PG              G +   G+ G        G P   G   A   P  +    P+
Sbjct: 439 GRPGEPGLMGPRGLPGSPGNIGPAGKEGPVGLPGIDGRPGPIGPAGARGEPGNIGFPGPK 498

Query: 499 LPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPP 558
            P  DP ++  +     A     G R   GP     A   P P+      GE  GPP PP
Sbjct: 499 GPTGDPGKNGDKGHAGLA-----GARGAPGPDGNNGAQGPPGPQGVQGGKGE-QGPPGPP 552

Query: 559 PARALPAAVASARCSLRDPGGGSARIRSRPGRSG 592
             + LP            P G +  +  +PG  G
Sbjct: 553 GFQGLPG-----------PSGPAGEV-GKPGERG 574



 Score = 43.5 bits (101), Expect = 5e-04
 Identities = 61/222 (27%), Positives = 70/222 (31%), Gaps = 35/222 (15%)

Query: 402 GARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRG 460
           GA    G RG  G  GP GP         PG        G+      A      G RG  
Sbjct: 226 GAPGPAGARGSDGSVGPVGPAGPIGSAGPPGFPGAPGPKGEIGAVGNAGPAGPAGPRGEV 285

Query: 461 WGPG-AGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRT 519
             PG +G V   G  G       G + AA  P     P LP           P  AA  T
Sbjct: 286 GLPGLSGPVGPPGNPGANGLT--GAKGAAGLPGVAGAPGLPGPRGIPG----PVGAAGAT 339

Query: 520 ELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPP------------------GPPTPPPAR 561
              G VG+   A      G +  P S  P  PP                  GPP PP  R
Sbjct: 340 GARGLVGEPGPAGSKGESGNKGEPGSAGPQGPPGPSGEEGKRGPNGEAGSAGPPGPPGLR 399

Query: 562 ALPAA----VASARCSLRDPGG-----GSARIRSRPGRSGGP 594
             P +     A  R  +  P G     G A +R   G +G P
Sbjct: 400 GSPGSRGLPGADGRAGVMGPPGSRGASGPAGVRGPNGDAGRP 441



 Score = 42.0 bits (97), Expect = 0.002
 Identities = 82/338 (24%), Positives = 105/338 (31%), Gaps = 62/338 (18%)

Query: 272  GSQRGAALAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTEREPWGGEGAG 331
            GS+      G+   P AA   G   P  ++G      P  P  P  ++  R P G +G  
Sbjct: 775  GSRGDGGPPGMTGFPGAAGRTGPPGPSGISG------PPGPPGPAGKEGLRGPRGDQGPV 828

Query: 332  SRFKRLHDESPRPNF--------------------PQSLAEGLGVSPQAGARVGEAREAV 371
             R   +    P P F                    PQ L    G+    G+R       V
Sbjct: 829  GRTGEVGAVGP-PGFAGEKGPSGEAGTAGPPGTPGPQGLLGAPGILGLPGSRGERGLPGV 887

Query: 372  T--THERAHLDREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGP----GPWDDPA 425
                 E   L   G   AR G   A       GA  + G  G  G  GP    G      
Sbjct: 888  AGAVGEPGPLGIAGPPGAR-GPPGAVGSPGVNGAPGEAGRDGNPGNDGPPGRDGQPGHKG 946

Query: 426  RRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSG--GRRGVGNPERWG 483
             R  PG       AG            + G+RG   GP     P+G  G RG   P+   
Sbjct: 947  ERGYPGNIGPVGAAGAPGPHGPVGPAGKHGNRGET-GPSGPVGPAGAVGPRGPSGPQGIR 1005

Query: 484  GEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELG--GRVG----KGPGAP----- 532
            G+   P         LP +      +  P  A    + G  G VG    +GP  P     
Sbjct: 1006 GDKGEPGEKGPR--GLPGLKGHNGLQGLPGIAGHHGDQGAPGSVGPAGPRGPAGPSGPAG 1063

Query: 533  ------------PSALPGPRPRPDSLSPGEPPGPPTPP 558
                        P+ + GP+       P  PPGPP PP
Sbjct: 1064 KDGRTGHPGTVGPAGIRGPQGHQGPAGPPGPPGPPGPP 1101



 Score = 37.4 bits (85), Expect = 0.039
 Identities = 61/221 (27%), Positives = 69/221 (31%), Gaps = 37/221 (16%)

Query: 355 GVSPQAGARVGEAREAVTTHERAHLDREGEARARLGQAAAQMRREGWGARAKLGGRGVCG 414
           G +  AGAR G A       E  H  + G    R G    Q  R   G     G +G+ G
Sbjct: 124 GQTGPAGAR-GPAGPPGKAGEDGHPGKPGRPGER-GVVGPQGARGFPGTPGLPGFKGIRG 181

Query: 415 KCG----PGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRGWGPG-AGRVP 469
             G     G    P  +  PGA       GQ   R         G RGR   PG AG   
Sbjct: 182 HNGLDGLKGQPGAPGVKGEPGAPGENGTPGQTGARGLP------GERGRVGAPGPAGARG 235

Query: 470 SGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGP 529
           S G  G   P    G A  P                      P A   + E+G     GP
Sbjct: 236 SDGSVGPVGPAGPIGSAGPPG--------------------FPGAPGPKGEIGAVGNAGP 275

Query: 530 GAPPSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVASA 570
             P     GPR          P GPP  P A  L  A  +A
Sbjct: 276 AGPA----GPRGEVGLPGLSGPVGPPGNPGANGLTGAKGAA 312



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 41/137 (29%), Positives = 46/137 (33%), Gaps = 20/137 (14%)

Query: 462 GPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTEL 521
           GP   R P G R   G P R G +     P     P  P   P            +   L
Sbjct: 33  GPAGDRGPRGERGPPGPPGRDGEDGPTGPPG----PPGPPGPPGLGGNFAAQYDGKGVGL 88

Query: 522 G-GRVG-KGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVASARCSLRDPGG 579
           G G +G  GP  PP A   P P+      GEP  P    PA A            R P G
Sbjct: 89  GPGPMGLMGPRGPPGAAGAPGPQGFQGPAGEPGEPGQTGPAGA------------RGPAG 136

Query: 580 --GSARIRSRPGRSGGP 594
             G A     PG+ G P
Sbjct: 137 PPGKAGEDGHPGKPGRP 153


>gi|169204930 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 88/332 (26%), Positives = 106/332 (31%), Gaps = 59/332 (17%)

Query: 286 PSAAAAAGRHCPLRLAGQAPRTQ-PACPAAP-RMQQTEREPWGGEGAGSRFKR----LHD 339
           P    A G     RL  Q  R      P AP    +  R P   + +GS  +R    L  
Sbjct: 37  PPHTPATGTRSSYRLLPQKGRGNLRGAPTAPVSFSRIRRNPLRTQLSGSPPRRPTSVLRL 96

Query: 340 ESPRPNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDREGEARARLGQAAAQMRRE 399
            SP  + P+         P+AG      R AV T  R    R+G  R   G      +R 
Sbjct: 97  ASPAGDLPRR------PRPRAGGGRHSPRPAVGTIFRG--GRKGRLREGRGAVRGSGKRR 148

Query: 400 GWG-----ARAKLGGRGVC--GKCGPGPWDDPARRR----NPGAAARAKLAGQRAGRARA 448
           GWG      R++L G G    G   P  W      R     PG    A L G   G    
Sbjct: 149 GWGLRPQRVRSRLAGLGAPRGGAAAPRGWGGQGAERLGVHQPGLPTHAALRGGGGG---- 204

Query: 449 RTGSQVGSRGRGWGPGAGRVPSGGR------RGVGNPERWGGEAAAPRPSRVLLPELPAV 502
              S+ G  G    P   R P  GR      R +G+ ER  G AA  R  ++  P     
Sbjct: 205 ---SEGGGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRPH---- 257

Query: 503 DPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARA 562
                       AA R    GR     GA  S     RP                     
Sbjct: 258 ------------AAVRNSSRGR-----GAATSVSAAARPTRGGARGHRRADGRARGGCAQ 300

Query: 563 LPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
           L A   SA   L+D  G      + P RSG P
Sbjct: 301 LRAGTPSAPGGLQDCRGRQGEENAHPFRSGAP 332



 Score = 35.8 bits (81), Expect = 0.11
 Identities = 78/302 (25%), Positives = 98/302 (32%), Gaps = 62/302 (20%)

Query: 262 RHGGRAAAGL---GSQRGAALAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQ 318
           RH  R A G    G ++G    G      A   +G+     L  Q  R++ A   APR  
Sbjct: 115 RHSPRPAVGTIFRGGRKGRLREGR----GAVRGSGKRRGWGLRPQRVRSRLAGLGAPRGG 170

Query: 319 QTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGARV----GEAREAVTTH 374
                 WGG+GA    +RL    P      +L  G G S   G         AR+  +  
Sbjct: 171 AAAPRGWGGQGA----ERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRARQPPSGR 226

Query: 375 ERAHLDR-EGEARARLGQAA----AQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRN 429
            R    R  G A    G+AA     Q+ R     R    GRG                 +
Sbjct: 227 PRPRRTRLLGSAERHTGRAALARHGQLSRPHAAVRNSSRGRGAA--------------TS 272

Query: 430 PGAAARAKLAGQRAGR---ARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERW-GGE 485
             AAAR    G R  R    RAR G      G    PG G     GR+G  N   +  G 
Sbjct: 273 VSAAARPTRGGARGHRRADGRARGGCAQLRAGTPSAPG-GLQDCRGRQGEENAHPFRSGA 331

Query: 486 AAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDS 545
             +P P                        A R+ L  ++   P  PP     P P P  
Sbjct: 332 PFSPHPH-----------------------ASRSTLAAQLLPLPQPPPPPKLAPPPLPPW 368

Query: 546 LS 547
           LS
Sbjct: 369 LS 370


>gi|239753839 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 257

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 71/241 (29%), Positives = 89/241 (36%), Gaps = 47/241 (19%)

Query: 378 HLDREGEARARLGQAAAQMRREG--WGARAKLGGRGVCGKCGP----------------- 418
           H D++ + RA + Q   +++R+G  W  +  LG  G      P                 
Sbjct: 13  HSDKDRDFRAVVPQVN-ELQRKGLFWRYQKTLGPAGARRGHSPPTVAPAASAGSQEHPGA 71

Query: 419 -GPWDDPARRRNPGAAARA-KLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPSGG--RR 474
            GP   PAR    G  ARA + AG+RAG A    G    + GRG      R P+ G  R 
Sbjct: 72  GGPLCFPARSAAWGPPARASRAAGRRAGPA----GPPCRAPGRGRAAATRRSPAPGTARG 127

Query: 475 GVGNPERWGGEAAAPR------PSRVLLPELPAVD---PARDTRREPDAAAQRTELGGR- 524
                ER GG  AA        P+R L P          +R  RR   AA  R+    R 
Sbjct: 128 SPAGVERAGGATAASSAGTRSVPARRLPPPCGGTSLGAGSRALRRPGSAALPRSPSSSRR 187

Query: 525 --VGKGPGAPPSALPGPRPRPDSLSPGEPPG-----PPTPPPARALPAAVASARCSLRDP 577
                GPGAP    PG    P   +   PP       P PP     PAA      +  DP
Sbjct: 188 WAAMPGPGAPRPGAPG--TWPVGFAVAAPPAAAASVAPPPPAVAGAPAAAFRGWVAAPDP 245

Query: 578 G 578
           G
Sbjct: 246 G 246



 Score = 33.1 bits (74), Expect = 0.74
 Identities = 58/211 (27%), Positives = 68/211 (32%), Gaps = 22/211 (10%)

Query: 268 AAGLGSQRGAALAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTEREPWGG 327
           AA  GSQ      G +  P+ +AA G   P R +  A R   A PA P      R P  G
Sbjct: 60  AASAGSQEHPGAGGPLCFPARSAAWGP--PARASRAAGRR--AGPAGPPC----RAPGRG 111

Query: 328 EGAGSRFKRLHDESPRPNFPQSL------AEGLGVSPQAGARVGEAREAVTTHERAHLDR 381
             A +R       SP P   +        A G   +  AG R   AR          L  
Sbjct: 112 RAAATR------RSPAPGTARGSPAGVERAGGATAASSAGTRSVPARRLPPPCGGTSLGA 165

Query: 382 EGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAAR--AKLA 439
              A  R G AA           A + G G      PG W        P AAA   A   
Sbjct: 166 GSRALRRPGSAALPRSPSSSRRWAAMPGPGAPRPGAPGTWPVGFAVAAPPAAAASVAPPP 225

Query: 440 GQRAGRARARTGSQVGSRGRGWGPGAGRVPS 470
              AG   A     V +   G  PG    P+
Sbjct: 226 PAVAGAPAAAFRGWVAAPDPGCTPGTENAPA 256


>gi|71043876 undifferentiated embryonic cell transcription factor 1
           [Homo sapiens]
          Length = 341

 Score = 50.4 bits (119), Expect = 4e-06
 Identities = 79/297 (26%), Positives = 105/297 (35%), Gaps = 74/297 (24%)

Query: 298 LRLAGQAPRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAE-GLGV 356
           LR     P   PA P+        R P    G   R         RP  P +L E GL V
Sbjct: 3   LRPRRPPPLAPPAPPSPASPDPEPRTPGDAPGTPPR---------RPASPSALGELGLPV 53

Query: 357 SPQAGARVG------------------------EAREAVTTHERAHLDREGEARARLGQA 392
           SP +  R                          + R+A+ T+ R        A+ ++ + 
Sbjct: 54  SPGSAQRTPWSARETELLLGTLLQPAVWRALLLDRRQALPTYRRVSA---ALAQQQVRRT 110

Query: 393 AAQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRNPGAAARAKLAGQRAGRARARTGS 452
            AQ RR     + K   R   G+  PGP+D+  R          KL G      R R   
Sbjct: 111 PAQCRRRYKFLKDKF--REAHGQ-PPGPFDEQIR----------KLMGLLGDNGRKRP-- 155

Query: 453 QVGSRGRGWGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREP 512
                 R   PG+GR P   RR V N       A AP PS    P+   +  ARD   +P
Sbjct: 156 ------RRRSPGSGR-PQRARRPVPN-------AHAPAPSE---PDATPLPTARDRDADP 198

Query: 513 DAAAQRTELGGR---VGKGPGAPPSALPGPRPR--PDSLSPGEPPGPPTPPPARALP 564
               + +    +       PG+PP+  P       P+  +P   PG P PPPAR  P
Sbjct: 199 TWTLRFSPSPPKSADASPAPGSPPAPAPTALATCIPEDRAPVRGPGSPPPPPAREDP 255



 Score = 34.7 bits (78), Expect = 0.25
 Identities = 21/47 (44%), Positives = 24/47 (51%), Gaps = 4/47 (8%)

Query: 529 PGAPPS-ALPGPRPRPDSLSPGEPPGPPTPPPA---RALPAAVASAR 571
           P APPS A P P PR    +PG PP  P  P A     LP +  SA+
Sbjct: 13  PPAPPSPASPDPEPRTPGDAPGTPPRRPASPSALGELGLPVSPGSAQ 59


>gi|239750393 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 88/332 (26%), Positives = 106/332 (31%), Gaps = 59/332 (17%)

Query: 286 PSAAAAAGRHCPLRLAGQAPRTQ-PACPAAP-RMQQTEREPWGGEGAGSRFKR----LHD 339
           P    A G     RL  Q  R      P AP    +  R P   + +GS  +R    L  
Sbjct: 37  PPHTPATGTRSSYRLLPQKGRGNLRGAPTAPVSFSRIRRNPLRTQLSGSPPRRPTSVLRL 96

Query: 340 ESPRPNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDREGEARARLGQAAAQMRRE 399
            SP  + P+         P+AG      R AV T  R    R+G  R   G      +R 
Sbjct: 97  ASPAGDLPRR------PRPRAGGGRHSPRPAVGTIFRG--GRKGRLREGRGALRGSGKRR 148

Query: 400 GWG-----ARAKLGGRGVC--GKCGPGPWDDPARRR----NPGAAARAKLAGQRAGRARA 448
           GWG      R++L G G    G   P  W      R     PG    A L G   G    
Sbjct: 149 GWGLRPQRVRSRLAGLGAPRGGAAAPRGWGGQGAERLGVHQPGLPTHAALRGGGGG---- 204

Query: 449 RTGSQVGSRGRGWGPGAGRVPSGGR------RGVGNPERWGGEAAAPRPSRVLLPELPAV 502
              S+ G  G    P   R P  GR      R +G+ ER  G AA  R  ++  P     
Sbjct: 205 ---SEGGGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRPH---- 257

Query: 503 DPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARA 562
                       AA R    GR     GA  S     RP                     
Sbjct: 258 ------------AAVRNSSRGR-----GAATSVSAAARPTRGGARGHRRADGRARGGCAQ 300

Query: 563 LPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
           L A   SA   L+D  G      + P RSG P
Sbjct: 301 LRAGTPSAPGGLQDCRGRQGEENAHPFRSGAP 332



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 78/302 (25%), Positives = 98/302 (32%), Gaps = 62/302 (20%)

Query: 262 RHGGRAAAGL---GSQRGAALAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQ 318
           RH  R A G    G ++G    G      A   +G+     L  Q  R++ A   APR  
Sbjct: 115 RHSPRPAVGTIFRGGRKGRLREGR----GALRGSGKRRGWGLRPQRVRSRLAGLGAPRGG 170

Query: 319 QTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGARV----GEAREAVTTH 374
                 WGG+GA    +RL    P      +L  G G S   G         AR+  +  
Sbjct: 171 AAAPRGWGGQGA----ERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRARQPPSGR 226

Query: 375 ERAHLDR-EGEARARLGQAA----AQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRN 429
            R    R  G A    G+AA     Q+ R     R    GRG                 +
Sbjct: 227 PRPRRTRLLGSAERHTGRAALARHGQLSRPHAAVRNSSRGRGAA--------------TS 272

Query: 430 PGAAARAKLAGQRAGR---ARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERW-GGE 485
             AAAR    G R  R    RAR G      G    PG G     GR+G  N   +  G 
Sbjct: 273 VSAAARPTRGGARGHRRADGRARGGCAQLRAGTPSAPG-GLQDCRGRQGEENAHPFRSGA 331

Query: 486 AAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDS 545
             +P P                        A R+ L  ++   P  PP     P P P  
Sbjct: 332 PFSPHPH-----------------------ASRSTLAAQLLPLPQPPPPPKLAPPPLPPW 368

Query: 546 LS 547
           LS
Sbjct: 369 LS 370


>gi|239744694 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 373

 Score = 50.1 bits (118), Expect = 6e-06
 Identities = 88/332 (26%), Positives = 106/332 (31%), Gaps = 59/332 (17%)

Query: 286 PSAAAAAGRHCPLRLAGQAPRTQ-PACPAAP-RMQQTEREPWGGEGAGSRFKR----LHD 339
           P    A G     RL  Q  R      P AP    +  R P   + +GS  +R    L  
Sbjct: 37  PPHTPATGTRSSYRLLPQKGRGNLRGAPTAPVSFSRIRRNPLRTQLSGSPPRRPTSVLRL 96

Query: 340 ESPRPNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDREGEARARLGQAAAQMRRE 399
            SP  + P+         P+AG      R AV T  R    R+G  R   G      +R 
Sbjct: 97  ASPAGDLPRR------PRPRAGGGRHSPRPAVGTIFRG--GRKGRLREGRGALRGSGKRR 148

Query: 400 GWG-----ARAKLGGRGVC--GKCGPGPWDDPARRR----NPGAAARAKLAGQRAGRARA 448
           GWG      R++L G G    G   P  W      R     PG    A L G   G    
Sbjct: 149 GWGLRPQRVRSRLAGLGAPRGGAAAPRGWGGQGAERLGVHQPGLPTHAALRGGGGG---- 204

Query: 449 RTGSQVGSRGRGWGPGAGRVPSGGR------RGVGNPERWGGEAAAPRPSRVLLPELPAV 502
              S+ G  G    P   R P  GR      R +G+ ER  G AA  R  ++  P     
Sbjct: 205 ---SEGGGGGARPSPPRARQPPSGRPRPRRTRLLGSAERHTGRAALARHGQLSRPH---- 257

Query: 503 DPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARA 562
                       AA R    GR     GA  S     RP                     
Sbjct: 258 ------------AAVRNSSRGR-----GAATSVSAAARPTRGGARGHRRADGRARGGCAQ 300

Query: 563 LPAAVASARCSLRDPGGGSARIRSRPGRSGGP 594
           L A   SA   L+D  G      + P RSG P
Sbjct: 301 LRAGTPSAPGGLQDCRGRQGEENAHPFRSGAP 332



 Score = 35.4 bits (80), Expect = 0.15
 Identities = 78/302 (25%), Positives = 98/302 (32%), Gaps = 62/302 (20%)

Query: 262 RHGGRAAAGL---GSQRGAALAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQ 318
           RH  R A G    G ++G    G      A   +G+     L  Q  R++ A   APR  
Sbjct: 115 RHSPRPAVGTIFRGGRKGRLREGR----GALRGSGKRRGWGLRPQRVRSRLAGLGAPRGG 170

Query: 319 QTEREPWGGEGAGSRFKRLHDESPRPNFPQSLAEGLGVSPQAGARV----GEAREAVTTH 374
                 WGG+GA    +RL    P      +L  G G S   G         AR+  +  
Sbjct: 171 AAAPRGWGGQGA----ERLGVHQPGLPTHAALRGGGGGSEGGGGGARPSPPRARQPPSGR 226

Query: 375 ERAHLDR-EGEARARLGQAA----AQMRREGWGARAKLGGRGVCGKCGPGPWDDPARRRN 429
            R    R  G A    G+AA     Q+ R     R    GRG                 +
Sbjct: 227 PRPRRTRLLGSAERHTGRAALARHGQLSRPHAAVRNSSRGRGAA--------------TS 272

Query: 430 PGAAARAKLAGQRAGR---ARARTGSQVGSRGRGWGPGAGRVPSGGRRGVGNPERW-GGE 485
             AAAR    G R  R    RAR G      G    PG G     GR+G  N   +  G 
Sbjct: 273 VSAAARPTRGGARGHRRADGRARGGCAQLRAGTPSAPG-GLQDCRGRQGEENAHPFRSGA 331

Query: 486 AAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDS 545
             +P P                        A R+ L  ++   P  PP     P P P  
Sbjct: 332 PFSPHPH-----------------------ASRSTLAAQLLPLPQPPPPPKLAPPPLPPW 368

Query: 546 LS 547
           LS
Sbjct: 369 LS 370


>gi|89363017 alpha 2 type V collagen preproprotein [Homo sapiens]
          Length = 1499

 Score = 49.7 bits (117), Expect = 8e-06
 Identities = 158/626 (25%), Positives = 204/626 (32%), Gaps = 94/626 (15%)

Query: 5    PRRPQPAGSTSTDILYG------LCGHLLDAGDEGGQAGHPVVGDTGQ-FERGCARRHRS 57
            P  P P GST    + G      + G   +AG +G    H + G  G   E G     R 
Sbjct: 449  PGSPGPQGSTGPQGIRGQPGDPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEG----KRG 504

Query: 58   PRGHRHAV--PGPRLQR-ALGGQAWAGRRQLHGFMLYSGQQ----RDGHRGGHDVGGRGG 110
            PRG    V  PGP  +R A G + + G   L G     G++      G +G     GR G
Sbjct: 505  PRGDPGTVGPPGPVGERGAPGNRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPG 564

Query: 111  GGRLQLVAGALGLGAGVLDHSGLRVAVGRAHLEHEVGAALHDVLDLQEAGRVHDHELLAG 170
               L    G  G   GV    G    +G    +   G      +  Q            G
Sbjct: 565  EPGLPGARGLTG-NPGVQGPEGKLGPLGAPGEDGRPGPPGSIGIRGQPGSMGLPGP--KG 621

Query: 171  RHGEPARVAEGQDLLEAGGRHGAGQLEGALA----VAAEQVAEVEAAGGQHRPVGLEGLA 226
              G+P +  E  +     G+ GA   +G +     V    +A      G   P G +GL 
Sbjct: 622  SSGDPGKPGEAGNA-GVPGQRGAPGKDGEVGPSGPVGPPGLAGERGEQGPPGPTGFQGLP 680

Query: 227  LDHDGHIAVEAQQALLVQAAQHCVP----EVGDLDVQHLRHGGRAAAGLGSQRGAALAGL 282
                G      +     +     VP     VG L       G R   G   +RG    G+
Sbjct: 681  ----GPPGPPGEGG---KPGDQGVPGDPGAVGPL-------GPRGERGNPGERGEP--GI 724

Query: 283  IYLPSAAAAAGRHCPLRLAGQ-APRTQPACPAAPRMQQTEREPWGGEGAGSRFKRLHDES 341
              LP     AG H P    G   P   P     P +Q    E       G +        
Sbjct: 725  TGLPGEKGMAGGHGPDGPKGSPGPSGTPGDTGPPGLQGMPGERGIAGTPGPK-------G 777

Query: 342  PRPNFPQSLAEGLGVSPQAGAR-----VGEAREAVTTHERAHLDREGEARARLGQAAAQM 396
             R    +  AEG   +   GAR     +G    A  T E+      GE   R G      
Sbjct: 778  DRGGIGEKGAEG--TAGNDGARGLPGPLGPPGPAGPTGEK------GEPGPR-GLVGPPG 828

Query: 397  RREGWGARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVG 455
             R   G+R + G  G  G  GP GP   P  +  PG   +   AG    +  A      G
Sbjct: 829  SRGNPGSRGENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLA---GSPG 885

Query: 456  SRGRGWGPGAGRVPSGGRRGVGNPERWG-----GEAAAPRPSRVLLPELPAVDPARDTRR 510
              G    PG      GGR   G P   G     G    P P+    P  P  +P ++   
Sbjct: 886  PHGPNGVPGL----KGGRGTQGPPGATGFPGSAGRVGPPGPAGAPGPAGPLGEPGKEG-- 939

Query: 511  EPDAAAQRTELGGRVG-KGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARALPAAVAS 569
             P          GRVG +GP  PP   PG +  P       P GPP        PA    
Sbjct: 940  -PPGLRGDPGSHGRVGDRGPAGPPGG-PGDKGDPGEDGQPGPDGPPG-------PAGTTG 990

Query: 570  ARCSLRDPG-GGSARIRSRPGRSGGP 594
             R  +  PG  G   +   PG +G P
Sbjct: 991  QRGIVGMPGQRGERGMPGLPGPAGTP 1016



 Score = 43.9 bits (102), Expect = 4e-04
 Identities = 46/173 (26%), Positives = 55/173 (31%), Gaps = 17/173 (9%)

Query: 402  GARAKLGGRGVCGKCG-PGPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRG 460
            G+  ++G RG  G  G PG   DP     PG       AG    R       Q G RG  
Sbjct: 948  GSHGRVGDRGPAGPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMP 1007

Query: 461  WGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTE 520
              PG    P     G   P    G+   P P        P  +P  +     D    R  
Sbjct: 1008 GLPGPAGTP-----GKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRDG 1062

Query: 521  LGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGP-----------PTPPPARA 562
              G  G      P+ LPG +  P +  P   PG            P  PP RA
Sbjct: 1063 AVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRGDPGSRGPIGPPGRA 1115



 Score = 42.7 bits (99), Expect = 0.001
 Identities = 62/221 (28%), Positives = 73/221 (33%), Gaps = 33/221 (14%)

Query: 402 GARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRA-------RARTG-- 451
           GA  + G  G+ GK GP GP   P     PG       AG    R        R  TG  
Sbjct: 351 GAPGQRGAHGMPGKPGPMGPLGIPGSSGFPGNPGMKGEAGPTGARGPEGPQGQRGETGPP 410

Query: 452 SQVGSRGRGWGPGAGRVPSG----GRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARD 507
             VGS G     G    P      G  G   P    G   +P P     P+     P   
Sbjct: 411 GPVGSPGLPGAIGTDGTPGAKGPTGSPGTSGPPGSAGPPGSPGPQGSTGPQGIRGQPG-- 468

Query: 508 TRREPDAAAQRTELG--GRVG----KGPGAPPS--ALPGPRPRPDSLSPGEPPGPPTPPP 559
              +P     + E G  G  G    +GP  PP      GPR  P ++ P  P G    P 
Sbjct: 469 ---DPGVPGFKGEAGPKGEPGPHGIQGPIGPPGEEGKRGPRGDPGTVGPPGPVGERGAPG 525

Query: 560 ARALPAAVA----SARCSLRDPGGGSARIRSR--PGRSGGP 594
            R  P +            R P G S    S+  PGR G P
Sbjct: 526 NRGFPGSDGLPGPKGAQGERGPVGSSGPKGSQGDPGRPGEP 566



 Score = 42.4 bits (98), Expect = 0.001
 Identities = 92/365 (25%), Positives = 116/365 (31%), Gaps = 57/365 (15%)

Query: 264 GGRAAAGLGSQRGAALAGLIYLPSAAAAAGRHCPLRLAG-QAPRTQ--PACPAAPRMQQ- 319
           GG    G G +      GL+  P      GR  P    G Q PR +  P     PR  Q 
Sbjct: 102 GGNTNFGRGRKGQKGEPGLV--PVVTGIRGRPGPAGPPGSQGPRGERGPKGRPGPRGPQG 159

Query: 320 TEREPWGGEGAGSRFKRLHDESPRPN-----FPQSLA---EGLGVSPQAGARVGEAREAV 371
            + EP      G+     H   P P+     F   +A   E  G+  Q G   G      
Sbjct: 160 IDGEPGVPGQPGAPGPPGHPSHPGPDGLSRPFSAQMAGLDEKSGLGSQVGLMPGSVGPVG 219

Query: 372 TTHERAHLDREGEARARLGQAAAQMRREGWGARAKLGGRGVCGKCG-PGPWDDPARRRNP 430
               +    ++G A    G           G    +G RG  G  G PG   +P R  NP
Sbjct: 220 PRGPQGLQGQQGGA----GPTGPPGEPGDPGPMGPIGSRGPEGPPGKPGEDGEPGRNGNP 275

Query: 431 GAAARAKLAGQRAGRARARTGSQVGSRG-RGWGPGAGRVPSGGRRGVGNPERWGGEAAAP 489
           G    A   G R            G RG +G     G V + G +G         EA   
Sbjct: 276 GEVGFAGSPGARGFPGAPGLPGLKGHRGHKGLEGPKGEVGAPGSKG---------EAGPT 326

Query: 490 RPSRVLLPELPAVDPARDTRREPDAAAQRTELGGRVGKGPGAPPSALPGPRPRPDSLSPG 549
            P   + P  P   P    R  P  A  +    G  GK     P  +PG    P   +PG
Sbjct: 327 GPMGAMGPLGPRGMPGERGRLGPQGAPGQRGAHGMPGKPGPMGPLGIPGSSGFPG--NPG 384

Query: 550 -------------EPP-------GPPTPPPARALPAAVASARCSLRDPGGGSARIRSRPG 589
                        E P       GPP P  +  LP A+ +      D   G+      PG
Sbjct: 385 MKGEAGPTGARGPEGPQGQRGETGPPGPVGSPGLPGAIGT------DGTPGAKGPTGSPG 438

Query: 590 RSGGP 594
            SG P
Sbjct: 439 TSGPP 443



 Score = 40.0 bits (92), Expect = 0.006
 Identities = 54/200 (27%), Positives = 64/200 (32%), Gaps = 24/200 (12%)

Query: 402  GARAKLGGRGVCGKCGP-GPWDDPARRRNPGAAARAKLAGQRAGRARARTGSQVGSRGRG 460
            G+  ++G  G  G  GP GP  +P +   PG      L G      R      VG RG  
Sbjct: 912  GSAGRVGPPGPAGAPGPAGPLGEPGKEGPPG------LRGDPGSHGR------VGDRGPA 959

Query: 461  WGPGAGRVPSGGRRGVGNPERWGGEAAAPRPSRVLLPELPAVDPARDTRREPDAAAQRTE 520
             GP  G    G     G P   G    A    +  +  +P     R     P  A    +
Sbjct: 960  -GPPGGPGDKGDPGEDGQPGPDGPPGPAGTTGQRGIVGMPGQRGERGMPGLPGPAGTPGK 1018

Query: 521  LGGRVGKGPGAPPSALPGPRPRPDSLSPGEPPGPPTPPPARALPA--AVASARCSLRDPG 578
            +G     G   PP    GP   P S  P   PGP  P      P        R    DPG
Sbjct: 1019 VGPTGATGDKGPP----GPVGPPGSNGPVGEPGPEGPAGNDGTPGRDGAVGERGDRGDPG 1074

Query: 579  ----GGSARIRSRPGRSGGP 594
                 GS      PG  G P
Sbjct: 1075 PAGLPGSQGAPGTPGPVGAP 1094



 Score = 36.2 bits (82), Expect = 0.087
 Identities = 100/419 (23%), Positives = 123/419 (29%), Gaps = 77/419 (18%)

Query: 215  GQHRPVGLEGLALDH--DGHIAVEAQQALLVQAAQHCVPEVGDLDVQHLRHGGRAAAGLG 272
            G++ P G  G A     DG   V+ +     Q      P    L      HG     GL 
Sbjct: 837  GENGPTGAVGFAGPQGPDGQPGVKGEPGEPGQKGDAGSPGPQGLAGSPGPHGPNGVPGLK 896

Query: 273  SQRGA-ALAGLIYLPSAAAAAGRHCPLRLAGQAPRTQPACPAAPRMQQTEREPWGGEGAG 331
              RG     G    P +A   G   P    G         PA P  +  +  P G  G  
Sbjct: 897  GGRGTQGPPGATGFPGSAGRVGPPGPAGAPG---------PAGPLGEPGKEGPPGLRGDP 947

Query: 332  SRFKRLHDESPR--PNFPQSLAEGLGVSPQAGARVGEAREAVTTHERAHLDREGEARARL 389
                R+ D  P   P  P    +  G   Q G   G    A TT +R  +   G+     
Sbjct: 948  GSHGRVGDRGPAGPPGGPGDKGDP-GEDGQPGPD-GPPGPAGTTGQRGIVGMPGQR---- 1001

Query: 390  GQAAAQMRREGWGARAKLGGRGVCGKCGP----------GPWDDPARRR---NPGAAARA 436
            G+          G   K+G  G  G  GP          GP  +P       N G   R 
Sbjct: 1002 GERGMPGLPGPAGTPGKVGPTGATGDKGPPGPVGPPGSNGPVGEPGPEGPAGNDGTPGRD 1061

Query: 437  KLAGQRAGRARARTGSQVGSRGRGWGPGAGRVPS-GGRRGVGNPERWGGEAAAPRPSRVL 495
               G+R  R         GS+G    PG    P   G+RG  +P   G       P R  
Sbjct: 1062 GAVGERGDRGDPGPAGLPGSQGAPGTPGPVGAPGDAGQRG--DP---GSRGPIGPPGRAG 1116

Query: 496  LPELPAVDPARDTRREPDAAAQRTELGGRVGKG----PGAP----------------PSA 535
               LP     R  + +      R + G R   G    PG P                P  
Sbjct: 1117 KRGLPGPQGPRGDKGDHGDRGDRGQKGHRGFTGLQGLPGPPGPNGEQGSAGIPGPFGPRG 1176

Query: 536  LPGP------RPRPDSLSP----------GE--PPGPPTPPPARALPAAVASARCSLRD 576
             PGP         P  L P          GE  P GPP  P     P        +L D
Sbjct: 1177 PPGPVGPSGKEGNPGPLGPIGPPGVRGSVGEAGPEGPPGEPGPPGPPGPPGHLTAALGD 1235


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.316    0.137    0.428 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 30,598,304
Number of Sequences: 37866
Number of extensions: 2069986
Number of successful extensions: 28913
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 386
Number of HSP's successfully gapped in prelim test: 1653
Number of HSP's that attempted gapping in prelim test: 15378
Number of HSP's gapped (non-prelim): 9884
length of query: 594
length of database: 18,247,518
effective HSP length: 108
effective length of query: 486
effective length of database: 14,157,990
effective search space: 6880783140
effective search space used: 6880783140
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 65 (29.6 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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