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Search of human proteins with 10863899
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]
(609 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|10863899 numb homolog (Drosophila)-like [Homo sapiens] 1250 0.0
gi|54144629 numb homolog isoform 4 [Homo sapiens] 597 e-170
gi|54144627 numb homolog isoform 2 [Homo sapiens] 588 e-168
gi|20070356 numb homolog isoform 3 [Homo sapiens] 574 e-164
gi|54144625 numb homolog isoform 1 [Homo sapiens] 566 e-161
gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Hom... 78 3e-14
gi|55750053 atrophin-1 [Homo sapiens] 70 4e-12
gi|55750041 atrophin-1 [Homo sapiens] 70 4e-12
gi|132626790 low density lipoprotein receptor adaptor protein 1 ... 70 7e-12
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi... 69 1e-11
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens] 69 1e-11
gi|32307128 nuclear receptor coactivator 6 [Homo sapiens] 67 4e-11
gi|55956910 meningioma 1 [Homo sapiens] 67 6e-11
gi|56549696 E1A binding protein p400 [Homo sapiens] 66 8e-11
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens] 66 8e-11
gi|9945318 MAX binding protein [Homo sapiens] 66 1e-10
gi|149158690 HLA-B associated transcript-2 [Homo sapiens] 66 1e-10
gi|47132519 Ras association and pleckstrin homology domains 1 is... 66 1e-10
gi|119943102 CREB binding protein isoform b [Homo sapiens] 65 1e-10
gi|119943104 CREB binding protein isoform a [Homo sapiens] 65 1e-10
gi|163965366 nascent polypeptide-associated complex alpha subuni... 65 1e-10
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi... 65 2e-10
gi|78042577 MAP7 domain containing 1 [Homo sapiens] 64 5e-10
gi|90903231 huntingtin [Homo sapiens] 63 7e-10
gi|160707881 formin 2 [Homo sapiens] 62 2e-09
gi|112734870 hypothetical protein LOC57648 [Homo sapiens] 62 2e-09
gi|21237805 SWI/SNF-related matrix-associated actin-dependent re... 61 3e-09
gi|148277037 AP2 associated kinase 1 [Homo sapiens] 61 3e-09
gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens] 60 4e-09
gi|50511947 cajalin 2 isoform b [Homo sapiens] 60 4e-09
>gi|10863899 numb homolog (Drosophila)-like [Homo sapiens]
Length = 609
Score = 1250 bits (3234), Expect = 0.0
Identities = 609/609 (100%), Positives = 609/609 (100%)
Query: 1 MSRSAAASGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAYVPEA 60
MSRSAAASGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAYVPEA
Sbjct: 1 MSRSAAASGGPRRPERHLPPAPCGAPGPPETCRTEPDGAGTMNKLRQSLRRRKPAYVPEA 60
Query: 61 SRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWV 120
SRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWV
Sbjct: 61 SRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGRKSVKSVLWV 120
Query: 121 SADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDS 180
SADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDS
Sbjct: 121 SADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALKDS 180
Query: 181 GERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPD 240
GERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPD
Sbjct: 181 GERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPD 240
Query: 241 KKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQL 300
KKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQL
Sbjct: 241 KKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQL 300
Query: 301 VRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSI 360
VRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSI
Sbjct: 301 VRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSI 360
Query: 361 NALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEV 420
NALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEV
Sbjct: 361 NALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEV 420
Query: 421 SQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVF 480
SQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVF
Sbjct: 421 SQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVF 480
Query: 481 LPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAF 540
LPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAF
Sbjct: 481 LPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAF 540
Query: 541 PPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEKPSNPFSGD 600
PPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEKPSNPFSGD
Sbjct: 541 PPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEKPSNPFSGD 600
Query: 601 LQKTFEIEL 609
LQKTFEIEL
Sbjct: 601 LQKTFEIEL 609
>gi|54144629 numb homolog isoform 4 [Homo sapiens]
Length = 592
Score = 597 bits (1539), Expect = e-170
Identities = 348/625 (55%), Positives = 402/625 (64%), Gaps = 90/625 (14%)
Query: 42 MNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCED 101
MNKLRQS RR+K YVPEASRPHQWQ DE+ VR G CSFPV+YLGHVEV+ESRGMH+CED
Sbjct: 1 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60
Query: 102 AVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYIC 161
AVK+LKA G+K+VK+VLWVSADGLRVVD+KTKDL+VDQTIEKVSFCAPDRN D+AFSYIC
Sbjct: 61 AVKRLKATGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYIC 120
Query: 162 RDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAR 221
RDGTTRRWICHCF+A+KD+GERLSHAVGCAFAACLERKQ+REKECGVTA FDASRT+F R
Sbjct: 121 RDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTR 180
Query: 222 EGSFRLSGGGRPAERE-----APDKKKAEA---AAAPTVAPGPAQPGHVSPTPATTSPGE 273
EGSFR++ AERE D KKAE +VAPG P SPT T+
Sbjct: 181 EGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATT 240
Query: 274 KGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPST 333
E P AIPRRHAP+EQL RQGSFRGFPALSQK SPFKRQLSLR+NELPST
Sbjct: 241 SLEMNNP-------HAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPST 293
Query: 334 LQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPP----------- 382
+QR+TDF +K VPE+E G+++SI++LC+QI+++F++ P P
Sbjct: 294 MQRKTDFPIKNAVPEVE----GEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 349
Query: 383 -PATTGTSAWGEPS-VPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQ 440
P GT WG+ S FQ GH+RTPSEA+RWLEEVS+ +AQQ Q
Sbjct: 350 SPTFQGTE-WGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQ---------- 398
Query: 441 QQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPP--------PHMQPPFVP 492
AS AP + P LQP P A+P Q FL P +QP FVP
Sbjct: 399 -------ASAAP---LQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVP 448
Query: 493 A--YP---GLGYPPMPRVPVVGITPSQMVANAFCSAAQLQ---PQPATLLGKAGAFPPPA 544
A YP G+ Y P P VPVVGITPSQMVAN F +A Q P + L + FP
Sbjct: 449 AQSYPVANGMPY-PAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYE 507
Query: 545 IPSAPGSQARPRP----NGAPW-------------PPEPAPAPAPELDPFEAQWAALEGK 587
SA S P NG+ P +DPFEAQWAALE K
Sbjct: 508 ASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENK 567
Query: 588 A---TVEKPSNPFSGDLQKTFEIEL 609
+ T P+NPFS DLQKTFEIEL
Sbjct: 568 SKQRTNPSPTNPFSSDLQKTFEIEL 592
>gi|54144627 numb homolog isoform 2 [Homo sapiens]
Length = 603
Score = 588 bits (1517), Expect = e-168
Identities = 348/636 (54%), Positives = 402/636 (63%), Gaps = 101/636 (15%)
Query: 42 MNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCED 101
MNKLRQS RR+K YVPEASRPHQWQ DE+ VR G CSFPV+YLGHVEV+ESRGMH+CED
Sbjct: 1 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60
Query: 102 AVKKLKA-----------MGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPD 150
AVK+LKA G+K+VK+VLWVSADGLRVVD+KTKDL+VDQTIEKVSFCAPD
Sbjct: 61 AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120
Query: 151 RNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTA 210
RN D+AFSYICRDGTTRRWICHCF+A+KD+GERLSHAVGCAFAACLERKQ+REKECGVTA
Sbjct: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180
Query: 211 AFDASRTSFAREGSFRLSGGGRPAERE-----APDKKKAEA---AAAPTVAPGPAQPGHV 262
FDASRT+F REGSFR++ AERE D KKAE +VAPG P
Sbjct: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240
Query: 263 SPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQ 322
SPT T+ E P AIPRRHAP+EQL RQGSFRGFPALSQK SPFKRQ
Sbjct: 241 SPTSPTSDATTSLEMNNP-------HAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQ 293
Query: 323 LSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPP 382
LSLR+NELPST+QR+TDF +K VPE+E G+++SI++LC+QI+++F++ P P
Sbjct: 294 LSLRINELPSTMQRKTDFPIKNAVPEVE----GEAESISSLCSQITNAFSTPEDPFSSAP 349
Query: 383 ------------PATTGTSAWGEPS-VPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQ 429
P GT WG+ S FQ GH+RTPSEA+RWLEEVS+ +AQQ
Sbjct: 350 MTKPVTVVAPQSPTFQGTE-WGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQP 408
Query: 430 QQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPP------ 483
Q AS AP + P LQP P A+P Q FL
Sbjct: 409 Q-----------------ASAAP---LQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVG 448
Query: 484 --PHMQPPFVPA--YP---GLGYPPMPRVPVVGITPSQMVANAFCSAAQLQ---PQPATL 533
P +QP FVPA YP G+ Y P P VPVVGITPSQMVAN F +A Q P +
Sbjct: 449 VVPALQPAFVPAQSYPVANGMPY-PAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPS 507
Query: 534 LGKAGAFPPPAIPSAPGSQARPRP----NGAPW-------------PPEPAPAPAPELDP 576
L + FP SA S P NG+ P +DP
Sbjct: 508 LVRQQTFPHYEASSATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDP 567
Query: 577 FEAQWAALEGKA---TVEKPSNPFSGDLQKTFEIEL 609
FEAQWAALE K+ T P+NPFS DLQKTFEIEL
Sbjct: 568 FEAQWAALENKSKQRTNPSPTNPFSSDLQKTFEIEL 603
>gi|20070356 numb homolog isoform 3 [Homo sapiens]
Length = 640
Score = 574 bits (1480), Expect = e-164
Identities = 350/672 (52%), Positives = 405/672 (60%), Gaps = 136/672 (20%)
Query: 42 MNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCED 101
MNKLRQS RR+K YVPEASRPHQWQ DE+ VR G CSFPV+YLGHVEV+ESRGMH+CED
Sbjct: 1 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60
Query: 102 AVKKLKAMGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYIC 161
AVK+LKA G+K+VK+VLWVSADGLRVVD+KTKDL+VDQTIEKVSFCAPDRN D+AFSYIC
Sbjct: 61 AVKRLKATGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPDRNFDRAFSYIC 120
Query: 162 RDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTAAFDASRTSFAR 221
RDGTTRRWICHCF+A+KD+GERLSHAVGCAFAACLERKQ+REKECGVTA FDASRT+F R
Sbjct: 121 RDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTATFDASRTTFTR 180
Query: 222 EGSFRLSGGGRPAERE-----APDKKKAEA---AAAPTVAPGPAQPGHVSPTPATTSPGE 273
EGSFR++ AERE D KKAE +VAPG P SPT T+
Sbjct: 181 EGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPSSPTSPTSDATT 240
Query: 274 KGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPST 333
E P AIPRRHAP+EQL RQGSFRGFPALSQK SPFKRQLSLR+NELPST
Sbjct: 241 SLEMNNP-------HAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQLSLRINELPST 293
Query: 334 LQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAP---APGPPPAT----- 385
+QR+TDF +K VPE+E G+++SI++LC+QI+++F++ P AP P T
Sbjct: 294 MQRKTDFPIKNAVPEVE----GEAESISSLCSQITNAFSTPEDPFSSAPMTKPVTVVAPQ 349
Query: 386 ------TGT-SAWGEPSVPPAAAFQP---------------------------------- 404
GT SA+ + P A P
Sbjct: 350 SPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIAATCSGTEWGQS 409
Query: 405 -----------GHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPV 453
GH+RTPSEA+RWLEEVS+ +AQQ Q AS AP
Sbjct: 410 SGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQ-----------------ASAAP- 451
Query: 454 PTMPPALQPFPAPVGPFDAAPAQVAVFLPP--------PHMQPPFVPA--YP---GLGYP 500
+ P LQP P A+P Q FL P +QP FVPA YP G+ Y
Sbjct: 452 --LQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQSYPVANGMPY- 508
Query: 501 PMPRVPVVGITPSQMVANAFCSAAQLQ---PQPATLLGKAGAFPPPAIPSAPGSQARPRP 557
P P VPVVGITPSQMVAN F +A Q P + L + FP SA S P
Sbjct: 509 PAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEASSATTSPFFKPP 568
Query: 558 ----NGAPW-------------PPEPAPAPAPELDPFEAQWAALEGKA---TVEKPSNPF 597
NG+ P +DPFEAQWAALE K+ T P+NPF
Sbjct: 569 AQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSKQRTNPSPTNPF 628
Query: 598 SGDLQKTFEIEL 609
S DLQKTFEIEL
Sbjct: 629 SSDLQKTFEIEL 640
>gi|54144625 numb homolog isoform 1 [Homo sapiens]
Length = 651
Score = 566 bits (1458), Expect = e-161
Identities = 350/683 (51%), Positives = 405/683 (59%), Gaps = 147/683 (21%)
Query: 42 MNKLRQSLRRRKPAYVPEASRPHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCED 101
MNKLRQS RR+K YVPEASRPHQWQ DE+ VR G CSFPV+YLGHVEV+ESRGMH+CED
Sbjct: 1 MNKLRQSFRRKKDVYVPEASRPHQWQTDEEGVRTGKCSFPVKYLGHVEVDESRGMHICED 60
Query: 102 AVKKLKA-----------MGRKSVKSVLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPD 150
AVK+LKA G+K+VK+VLWVSADGLRVVD+KTKDL+VDQTIEKVSFCAPD
Sbjct: 61 AVKRLKAERKFFKGFFGKTGKKAVKAVLWVSADGLRVVDEKTKDLIVDQTIEKVSFCAPD 120
Query: 151 RNLDKAFSYICRDGTTRRWICHCFLALKDSGERLSHAVGCAFAACLERKQRREKECGVTA 210
RN D+AFSYICRDGTTRRWICHCF+A+KD+GERLSHAVGCAFAACLERKQ+REKECGVTA
Sbjct: 121 RNFDRAFSYICRDGTTRRWICHCFMAVKDTGERLSHAVGCAFAACLERKQKREKECGVTA 180
Query: 211 AFDASRTSFAREGSFRLSGGGRPAERE-----APDKKKAEA---AAAPTVAPGPAQPGHV 262
FDASRT+F REGSFR++ AERE D KKAE +VAPG P
Sbjct: 181 TFDASRTTFTREGSFRVTTATEQAEREEIMKQMQDAKKAETDKIVVGSSVAPGNTAPSPS 240
Query: 263 SPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQ 322
SPT T+ E P AIPRRHAP+EQL RQGSFRGFPALSQK SPFKRQ
Sbjct: 241 SPTSPTSDATTSLEMNNP-------HAIPRRHAPIEQLARQGSFRGFPALSQKMSPFKRQ 293
Query: 323 LSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAP---AP 379
LSLR+NELPST+QR+TDF +K VPE+E G+++SI++LC+QI+++F++ P AP
Sbjct: 294 LSLRINELPSTMQRKTDFPIKNAVPEVE----GEAESISSLCSQITNAFSTPEDPFSSAP 349
Query: 380 GPPPAT-----------TGT-SAWGEPSVPPAAAFQP----------------------- 404
P T GT SA+ + P A P
Sbjct: 350 MTKPVTVVAPQSPTFQANGTDSAFHVLAKPAHTALAPVAMPVRETNPWAHAPDAANKEIA 409
Query: 405 ----------------------GHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQ 442
GH+RTPSEA+RWLEEVS+ +AQQ Q
Sbjct: 410 ATCSGTEWGQSSGAASPGLFQAGHRRTPSEADRWLEEVSKSVRAQQPQ------------ 457
Query: 443 QQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPP--------PHMQPPFVPA- 493
AS AP + P LQP P A+P Q FL P +QP FVPA
Sbjct: 458 -----ASAAP---LQPVLQPPPPTAISQPASPFQGNAFLTSQPVPVGVVPALQPAFVPAQ 509
Query: 494 -YP---GLGYPPMPRVPVVGITPSQMVANAFCSAAQLQ---PQPATLLGKAGAFPPPAIP 546
YP G+ Y P P VPVVGITPSQMVAN F +A Q P + L + FP
Sbjct: 510 SYPVANGMPY-PAPNVPVVGITPSQMVANVFGTAGHPQAAHPHQSPSLVRQQTFPHYEAS 568
Query: 547 SAPGSQARPRP----NGAPW-------------PPEPAPAPAPELDPFEAQWAALEGKA- 588
SA S P NG+ P +DPFEAQWAALE K+
Sbjct: 569 SATTSPFFKPPAQHLNGSAAFNGVDDGRLASADRHTEVPTGTCPVDPFEAQWAALENKSK 628
Query: 589 --TVEKPSNPFSGDLQKTFEIEL 609
T P+NPFS DLQKTFEIEL
Sbjct: 629 QRTNPSPTNPFSSDLQKTFEIEL 651
>gi|7705318 GULP, engulfment adaptor PTB domain containing 1 [Homo
sapiens]
Length = 304
Score = 77.8 bits (190), Expect = 3e-14
Identities = 41/134 (30%), Positives = 76/134 (56%), Gaps = 8/134 (5%)
Query: 66 WQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLK-------AMGRKSVKSVL 118
W +A+ K + ++LG EVE+ +G V DAV+KLK + G+K K L
Sbjct: 13 WMHTPEALSKHFIPYNAKFLGSTEVEQPKGTEVVRDAVRKLKFARHIKKSEGQKIPKVEL 72
Query: 119 WVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALK 178
+S G+++++ KTK++ + + ++SFCA D+ + F++IC+D + + +C+ F + K
Sbjct: 73 QISIYGVKILEPKTKEVQHNCQLHRISFCADDKTDKRIFTFICKDSESNKHLCYVFDSEK 132
Query: 179 DSGERLSHAVGCAF 192
E ++ +G AF
Sbjct: 133 -CAEEITLTIGQAF 145
>gi|55750053 atrophin-1 [Homo sapiens]
Length = 1190
Score = 70.5 bits (171), Expect = 4e-12
Identities = 105/390 (26%), Positives = 140/390 (35%), Gaps = 101/390 (25%)
Query: 253 APGPAQPGHVSPT---PATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGF 309
AP PA HV+P P P A P G A +P H P + QG G
Sbjct: 288 APPPANFPHVTPNLPPPPALRPLNNASASPP---GLGAQPLPG-HLPSPHAMGQG-MGGL 342
Query: 310 PALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISS 369
P +K L P +L + P M P + S S +A + SS
Sbjct: 343 PPGPEKGPT--------LAPSPHSLPPASS---SAPAPPMRFPYSSSSSS-SAAASSSSS 390
Query: 370 SFASAGAPAPG-----------PPPATTGTS----AWGEPSVPPAAAFQPGHKRTP---- 410
S +S+ +P P PPP + S + +PS+P A + G P
Sbjct: 391 SSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGR 450
Query: 411 ----SEAERWLEEVSQVAKA-------------QQQQQQQQQQQQQQQQQQQQAASVAPV 453
S A S A++ QQQQQQQQQQQQQQQQQQQ + P
Sbjct: 451 LLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPP 510
Query: 454 P---------------TMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLG 498
P P A+ P + P+ PA LPPPH Q + A P
Sbjct: 511 PPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAH----LPPPHSQVSYSQAGP--N 564
Query: 499 YPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGA-FPPPAIPSAPGSQA---- 553
PP ++ S +++ + P+ G GA +P P +P+ S A
Sbjct: 565 GPP--------VSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLST 616
Query: 554 -------RPRPNGAPWPPEPAP----APAP 572
P PP P P AP+P
Sbjct: 617 VIATVASSPAGYKTASPPGPPPYGKRAPSP 646
Score = 50.8 bits (120), Expect = 4e-06
Identities = 87/358 (24%), Positives = 125/358 (34%), Gaps = 73/358 (20%)
Query: 238 APDKKKAEAAAAPTVAPGPAQPGHV------SPTPATTSPGEKGEAGTPVAAGTTAAAIP 291
+P + ++ ++ ++ GPA+P H SP P ++P + + P + T
Sbjct: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGY-- 194
Query: 292 RRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEP 351
HAP+E + R F A P P T + G P M P
Sbjct: 195 --HAPMEP----PTSRMFQAPPGAPPPH-----------PQLYPGGTGGVLSG--PPMGP 235
Query: 352 PGAGDSDSINAL---------CTQIS-SSFASAGAPAPGPPPATTGTSAWGEPSVPPAAA 401
G G + S+ T IS SS ++GAP PP TT PS PP A
Sbjct: 236 KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPP--TTPVGGGNLPSAPPPAN 293
Query: 402 F-QPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPAL 460
F P A R L S P+P P+
Sbjct: 294 FPHVTPNLPPPPALRPLNNAS---------------------ASPPGLGAQPLPGHLPSP 332
Query: 461 QPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVA--N 518
+G P + P PH PP + P PPM R P + S A +
Sbjct: 333 HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA---PPM-RFPYSSSSSSSAAASSS 388
Query: 519 AFCSAAQLQPQPAT--LLGKAGAFPPP---AIPSAPGSQARPR-PNGAPWPPEPAPAP 570
+ S++ P PA+ L +FPPP ++ + P +P P+ A W P P P
Sbjct: 389 SSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPP 446
Score = 40.8 bits (94), Expect = 0.004
Identities = 86/366 (23%), Positives = 118/366 (32%), Gaps = 57/366 (15%)
Query: 220 AREGSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGT 279
A G S AE+ KKA A T P G E
Sbjct: 33 ASPGGVSTSSSDGKAEKSRQTAKKARVEEAST--------------PKVNKQGRSEEISE 78
Query: 280 PVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTD 339
+ T A P++ ++L R S +L ++ LN+ S+ R D
Sbjct: 79 SESEETNA---PKKTKTEQELPRPQSPSDLDSLDGRS----------LNDDGSSDPRDID 125
Query: 340 FQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVP-- 397
+ T P + PG+ ++DS SSS S G P PP S S P
Sbjct: 126 QDNRSTSPSIYSPGSVENDS-------DSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQ 178
Query: 398 PAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMP 457
P A+F+P TP+ +E + ++ Q Q V P M
Sbjct: 179 PEASFEPHPSVTPTGYHAPMEPPT----SRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMG 234
Query: 458 PALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPM--PRVPVVG--ITPS 513
P + VG + PP P V + G PP P PV G + +
Sbjct: 235 PKGGGAASSVGGPNGGKQH------PPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSA 288
Query: 514 QMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPN-------GAPWPPEP 566
AN L P PA + PP + + P P P+ G P PE
Sbjct: 289 PPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEK 348
Query: 567 APAPAP 572
P AP
Sbjct: 349 GPTLAP 354
Score = 34.3 bits (77), Expect = 0.34
Identities = 41/181 (22%), Positives = 71/181 (39%), Gaps = 30/181 (16%)
Query: 412 EAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFD 471
EAE+ E + + ++++++++++++++ ++ + A P P+L P P PF+
Sbjct: 806 EAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHR-PPFE 864
Query: 472 AAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPA 531
A V PP++ P PA L P V ++P + + P
Sbjct: 865 PGSAVATV---PPYLGPD-TPALRTLSEYARPHV----MSPGNRNHPFYVPLGAVDP--- 913
Query: 532 TLLGKAGAFPPPAIPSAPGSQARPR------------PNGAPWPPEPAP---APAPELDP 576
G G P S P ++ R R P P E P P P LDP
Sbjct: 914 ---GLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDP 970
Query: 577 F 577
F
Sbjct: 971 F 971
Score = 33.9 bits (76), Expect = 0.45
Identities = 66/313 (21%), Positives = 107/313 (34%), Gaps = 86/313 (27%)
Query: 346 VPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGP-PPATTGTSAWGEPSVPPAAAFQP 404
+P + PP A + TQI A P PPA + PS PP P
Sbjct: 705 LPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARS-------PSPPPKVVDVP 757
Query: 405 GH----------------------------------KRTPSEAERWLEEVSQVAKAQQQQ 430
H K+ E+ E Q A+ ++++
Sbjct: 758 SHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKER 817
Query: 431 QQQQQQQQQQQQQQQ-----------------QAASVAPVPTMPP-----ALQPFPAPVG 468
+++++++++++++++ + S+ PVP PP A+ P +G
Sbjct: 818 EREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLG 877
Query: 469 PFDAAPAQVAVFLPPPHMQP---------PFVPAYPG-LGYPPMPRVPVV-GITPSQMVA 517
P A ++ + P M P P PG LGY VP + P+
Sbjct: 878 PDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGY----NVPALYSSDPAARER 933
Query: 518 NAFCSAAQLQP--QPATLLGKAGAFPPPAIPSAPGSQARPRPNG---APWPPEPAPAP-A 571
L+ +P + + P +P PG PR G P PP P P
Sbjct: 934 EREARERDLRDRLKPGFEVKPSELEPLHGVP-GPGLDPFPRHGGLALQPGPPGLHPFPFH 992
Query: 572 PELDPFEAQWAAL 584
P L P E + AL
Sbjct: 993 PSLGPLERERLAL 1005
Score = 30.4 bits (67), Expect = 4.9
Identities = 32/134 (23%), Positives = 40/134 (29%), Gaps = 13/134 (9%)
Query: 472 AAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGI-TPSQMVANAFCSAAQLQPQP 530
A P PP P P P + P P V G P + + A P P
Sbjct: 156 ARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPP 215
Query: 531 ATLL---GKAGAFP-PPAIPSAPGSQAR-PRPNGAPWPPEPAPAPAPELDPFEAQWAALE 585
L G G PP P G+ + PNG P P P +
Sbjct: 216 HPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPT-------TPISVSSSGAS 268
Query: 586 GKATVEKPSNPFSG 599
G + P+ P G
Sbjct: 269 GAPPTKPPTTPVGG 282
>gi|55750041 atrophin-1 [Homo sapiens]
Length = 1190
Score = 70.5 bits (171), Expect = 4e-12
Identities = 105/390 (26%), Positives = 140/390 (35%), Gaps = 101/390 (25%)
Query: 253 APGPAQPGHVSPT---PATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGF 309
AP PA HV+P P P A P G A +P H P + QG G
Sbjct: 288 APPPANFPHVTPNLPPPPALRPLNNASASPP---GLGAQPLPG-HLPSPHAMGQG-MGGL 342
Query: 310 PALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISS 369
P +K L P +L + P M P + S S +A + SS
Sbjct: 343 PPGPEKGPT--------LAPSPHSLPPASS---SAPAPPMRFPYSSSSSS-SAAASSSSS 390
Query: 370 SFASAGAPAPG-----------PPPATTGTS----AWGEPSVPPAAAFQPGHKRTP---- 410
S +S+ +P P PPP + S + +PS+P A + G P
Sbjct: 391 SSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPPPYGR 450
Query: 411 ----SEAERWLEEVSQVAKA-------------QQQQQQQQQQQQQQQQQQQQAASVAPV 453
S A S A++ QQQQQQQQQQQQQQQQQQQ + P
Sbjct: 451 LLANSNAHPGPFPPSTGAQSTAHPPVSTHHHHHQQQQQQQQQQQQQQQQQQQHHGNSGPP 510
Query: 454 P---------------TMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLG 498
P P A+ P + P+ PA LPPPH Q + A P
Sbjct: 511 PPGAFPHPLEGGSSHHAHPYAMSPSLGSLRPYPPGPAH----LPPPHSQVSYSQAGP--N 564
Query: 499 YPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGA-FPPPAIPSAPGSQA---- 553
PP ++ S +++ + P+ G GA +P P +P+ S A
Sbjct: 565 GPP--------VSSSSNSSSSTSQGSYPCSHPSPSQGPQGAPYPFPPVPTVTTSSATLST 616
Query: 554 -------RPRPNGAPWPPEPAP----APAP 572
P PP P P AP+P
Sbjct: 617 VIATVASSPAGYKTASPPGPPPYGKRAPSP 646
Score = 50.8 bits (120), Expect = 4e-06
Identities = 87/358 (24%), Positives = 125/358 (34%), Gaps = 73/358 (20%)
Query: 238 APDKKKAEAAAAPTVAPGPAQPGHV------SPTPATTSPGEKGEAGTPVAAGTTAAAIP 291
+P + ++ ++ ++ GPA+P H SP P ++P + + P + T
Sbjct: 137 SPGSVENDSDSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGY-- 194
Query: 292 RRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEP 351
HAP+E + R F A P P T + G P M P
Sbjct: 195 --HAPMEP----PTSRMFQAPPGAPPPH-----------PQLYPGGTGGVLSG--PPMGP 235
Query: 352 PGAGDSDSINAL---------CTQIS-SSFASAGAPAPGPPPATTGTSAWGEPSVPPAAA 401
G G + S+ T IS SS ++GAP PP TT PS PP A
Sbjct: 236 KGGGAASSVGGPNGGKQHPPPTTPISVSSSGASGAPPTKPP--TTPVGGGNLPSAPPPAN 293
Query: 402 F-QPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPAL 460
F P A R L S P+P P+
Sbjct: 294 FPHVTPNLPPPPALRPLNNAS---------------------ASPPGLGAQPLPGHLPSP 332
Query: 461 QPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVA--N 518
+G P + P PH PP + P PPM R P + S A +
Sbjct: 333 HAMGQGMGGLPPGPEKGPTLAPSPHSLPPASSSAPA---PPM-RFPYSSSSSSSAAASSS 388
Query: 519 AFCSAAQLQPQPAT--LLGKAGAFPPP---AIPSAPGSQARPR-PNGAPWPPEPAPAP 570
+ S++ P PA+ L +FPPP ++ + P +P P+ A W P P P
Sbjct: 389 SSSSSSSASPFPASQALPSYPHSFPPPTSLSVSNQPPKYTQPSLPSQAVWSQGPPPPP 446
Score = 40.8 bits (94), Expect = 0.004
Identities = 86/366 (23%), Positives = 118/366 (32%), Gaps = 57/366 (15%)
Query: 220 AREGSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGT 279
A G S AE+ KKA A T P G E
Sbjct: 33 ASPGGVSTSSSDGKAEKSRQTAKKARVEEAST--------------PKVNKQGRSEEISE 78
Query: 280 PVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTD 339
+ T A P++ ++L R S +L ++ LN+ S+ R D
Sbjct: 79 SESEETNA---PKKTKTEQELPRPQSPSDLDSLDGRS----------LNDDGSSDPRDID 125
Query: 340 FQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVP-- 397
+ T P + PG+ ++DS SSS S G P PP S S P
Sbjct: 126 QDNRSTSPSIYSPGSVENDS-------DSSSGLSQGPARPYHPPPLFPPSPQPPDSTPRQ 178
Query: 398 PAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMP 457
P A+F+P TP+ +E + ++ Q Q V P M
Sbjct: 179 PEASFEPHPSVTPTGYHAPMEPPT----SRMFQAPPGAPPPHPQLYPGGTGGVLSGPPMG 234
Query: 458 PALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPM--PRVPVVG--ITPS 513
P + VG + PP P V + G PP P PV G + +
Sbjct: 235 PKGGGAASSVGGPNGGKQH------PPPTTPISVSSSGASGAPPTKPPTTPVGGGNLPSA 288
Query: 514 QMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPN-------GAPWPPEP 566
AN L P PA + PP + + P P P+ G P PE
Sbjct: 289 PPPANFPHVTPNLPPPPALRPLNNASASPPGLGAQPLPGHLPSPHAMGQGMGGLPPGPEK 348
Query: 567 APAPAP 572
P AP
Sbjct: 349 GPTLAP 354
Score = 34.3 bits (77), Expect = 0.34
Identities = 41/181 (22%), Positives = 71/181 (39%), Gaps = 30/181 (16%)
Query: 412 EAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFD 471
EAE+ E + + ++++++++++++++ ++ + A P P+L P P PF+
Sbjct: 806 EAEQRAREEKEREREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHR-PPFE 864
Query: 472 AAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPA 531
A V PP++ P PA L P V ++P + + P
Sbjct: 865 PGSAVATV---PPYLGPD-TPALRTLSEYARPHV----MSPGNRNHPFYVPLGAVDP--- 913
Query: 532 TLLGKAGAFPPPAIPSAPGSQARPR------------PNGAPWPPEPAP---APAPELDP 576
G G P S P ++ R R P P E P P P LDP
Sbjct: 914 ---GLLGYNVPALYSSDPAAREREREARERDLRDRLKPGFEVKPSELEPLHGVPGPGLDP 970
Query: 577 F 577
F
Sbjct: 971 F 971
Score = 33.9 bits (76), Expect = 0.45
Identities = 66/313 (21%), Positives = 107/313 (34%), Gaps = 86/313 (27%)
Query: 346 VPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGP-PPATTGTSAWGEPSVPPAAAFQP 404
+P + PP A + TQI A P PPA + PS PP P
Sbjct: 705 LPSLPPPPAAPASGPPLSATQIKQEPAEEYETPESPVPPARS-------PSPPPKVVDVP 757
Query: 405 GH----------------------------------KRTPSEAERWLEEVSQVAKAQQQQ 430
H K+ E+ E Q A+ ++++
Sbjct: 758 SHASQSARFNKHLDRGFNSCARSDLYFVPLEGSKLAKKRADLVEKVRREAEQRAREEKER 817
Query: 431 QQQQQQQQQQQQQQQ-----------------QAASVAPVPTMPP-----ALQPFPAPVG 468
+++++++++++++++ + S+ PVP PP A+ P +G
Sbjct: 818 EREREREKEREREKERELERSVKLAQEGRAPVECPSLGPVPHRPPFEPGSAVATVPPYLG 877
Query: 469 PFDAAPAQVAVFLPPPHMQP---------PFVPAYPG-LGYPPMPRVPVV-GITPSQMVA 517
P A ++ + P M P P PG LGY VP + P+
Sbjct: 878 PDTPALRTLSEYARPHVMSPGNRNHPFYVPLGAVDPGLLGY----NVPALYSSDPAARER 933
Query: 518 NAFCSAAQLQP--QPATLLGKAGAFPPPAIPSAPGSQARPRPNG---APWPPEPAPAP-A 571
L+ +P + + P +P PG PR G P PP P P
Sbjct: 934 EREARERDLRDRLKPGFEVKPSELEPLHGVP-GPGLDPFPRHGGLALQPGPPGLHPFPFH 992
Query: 572 PELDPFEAQWAAL 584
P L P E + AL
Sbjct: 993 PSLGPLERERLAL 1005
Score = 30.4 bits (67), Expect = 4.9
Identities = 32/134 (23%), Positives = 40/134 (29%), Gaps = 13/134 (9%)
Query: 472 AAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGI-TPSQMVANAFCSAAQLQPQP 530
A P PP P P P + P P V G P + + A P P
Sbjct: 156 ARPYHPPPLFPPSPQPPDSTPRQPEASFEPHPSVTPTGYHAPMEPPTSRMFQAPPGAPPP 215
Query: 531 ATLL---GKAGAFP-PPAIPSAPGSQAR-PRPNGAPWPPEPAPAPAPELDPFEAQWAALE 585
L G G PP P G+ + PNG P P P +
Sbjct: 216 HPQLYPGGTGGVLSGPPMGPKGGGAASSVGGPNGGKQHPPPT-------TPISVSSSGAS 268
Query: 586 GKATVEKPSNPFSG 599
G + P+ P G
Sbjct: 269 GAPPTKPPTTPVGG 282
>gi|132626790 low density lipoprotein receptor adaptor protein 1
[Homo sapiens]
Length = 308
Score = 69.7 bits (169), Expect = 7e-12
Identities = 45/151 (29%), Positives = 75/151 (49%), Gaps = 10/151 (6%)
Query: 63 PHQWQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKL----KAMGRKSVKSVL 118
P W + + +G F ++YLG VE+ +G + A+K++ KA G+K K L
Sbjct: 32 PENWTDTRETLLEGML-FSLKYLGMTLVEQPKGEELSAAAIKRIVATAKASGKKLQKVTL 90
Query: 119 WVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDGTTRRWICHCFLALK 178
VS G+ + D+ T L+ + +I ++S+C D+ DK F+YI + + CH FL K
Sbjct: 91 KVSPRGIILTDNLTNQLIENVSIYRISYCTADKMHDKVFAYIAQSQHNQSLECHAFLCTK 150
Query: 179 -DSGERLSHAVGCAFAACLE----RKQRREK 204
+ ++ V AF E K+ +EK
Sbjct: 151 RKMAQAVTLTVAQAFKVAFEFWQVSKEEKEK 181
>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
sapiens]
Length = 855
Score = 69.3 bits (168), Expect = 1e-11
Identities = 119/456 (26%), Positives = 158/456 (34%), Gaps = 84/456 (18%)
Query: 193 AACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGG--RPAEREAPDKKKAEAAAAP 250
A + RK E+ G+ A S R G R +G PA R + A A
Sbjct: 50 AGAVGRKPLAERAGGIGGA--TIPESAPRAGPTRSAGTSSRNPASRPPASGRGERAPPAK 107
Query: 251 TVAPGP-AQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRG- 308
+PGP + PG S TT PG G+ G ++A T A AP + G+ R
Sbjct: 108 NTSPGPVSSPGRAS---GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDT 164
Query: 309 --------FPALSQKNSPFKRQLSL-----RLNELPSTLQRRTDFQVKGTVPEMEP---- 351
PA+++++ ++ L P T R EP
Sbjct: 165 SGPTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAA 224
Query: 352 ---PGAGD------SDSINALCTQISSSFASAGAPAPGPP--------PATTGTSAWGEP 394
P AG S S+++ T +SS A +G A G P P G A P
Sbjct: 225 RRRPSAGGGLQRPASRSLSSSATPLSSP-ARSGPSARGTPRAPAHPSQPKPKGLQALRPP 283
Query: 395 SV-PPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPV 453
V PP P S L S A Q Q Q A+ P+
Sbjct: 284 QVTPPRKDAAPALGPLSSSP---LATPSPSAALQSQAPPTLPATPHSSSLTCQLATPLPL 340
Query: 454 ----PTMPPALQPFPAPVGPFDAAPAQVAV------------FLPPPHMQPPFVP---AY 494
P+ PP+LQ P+P P+Q FLP P + P P A
Sbjct: 341 APPSPSAPPSLQTLPSPPA---TPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAP 397
Query: 495 PGLGYPPM------PRVPVVG--ITPSQMVANAFC---SAAQLQPQPATLLGKAGAFP-- 541
P L PP+ P P + TPS NA A P P+ + + P
Sbjct: 398 PALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPAS 457
Query: 542 PPAIPSA-PGSQARPRPNGAPWPPEPAPAPAPELDP 576
PP PSA P SQA P P P+P +P + P
Sbjct: 458 PPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493
Score = 59.7 bits (143), Expect = 8e-09
Identities = 94/402 (23%), Positives = 133/402 (33%), Gaps = 51/402 (12%)
Query: 208 VTAAFDASRTSFAREGSFRLSGGG---RPAERE---------APDKKKAEAAAAPTVAPG 255
V++A + S T + R S GG RPA R +P + A P
Sbjct: 209 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 268
Query: 256 PAQP---GHVSPTPATTSPGEKGEA-------GTPVAAGTTAAAIPRRHAPLEQLVRQGS 305
P+QP G + P +P K A +P+A + +AA+ + P
Sbjct: 269 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAALQSQAPPT-------- 320
Query: 306 FRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCT 365
PA +S QL+ L P + Q + P P A + S+ +
Sbjct: 321 ---LPATPHSSS-LTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQA--TTSLGSPTL 374
Query: 366 QISSSFASA------GAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEE 419
Q + SF + P P PPA PS P + P +P
Sbjct: 375 QATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVH 434
Query: 420 VSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFD-AAPAQVA 478
+ Q A Q + S P PP+L P V P A+P
Sbjct: 435 LLQ-APFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSP 493
Query: 479 VFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVAN---AFCSAAQLQPQPATLLG 535
PPP PP L PP P + P Q + + +F A P + +
Sbjct: 494 SATPPPQAPPPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMS 553
Query: 536 KAGAFPPPAIP--SAPGSQARPRPNGAP--WPPEPAPAPAPE 573
PP A P +AP Q P P +P P P P P+
Sbjct: 554 PLATPPPQAPPVLAAPLLQVPPSPPASPTLQAPRRPPTPGPD 595
Score = 30.8 bits (68), Expect = 3.8
Identities = 45/188 (23%), Positives = 65/188 (34%), Gaps = 26/188 (13%)
Query: 239 PDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLE 298
P + + AAP + P+ P +P+ T P + A P+AA A P AP
Sbjct: 466 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ---APPPLAAPPLQLAKPPPQAPPA 522
Query: 299 QLVRQ-GSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTD------FQVKGTVPEM-- 349
+ PA +PF SL ++ L + + QV + P
Sbjct: 523 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 582
Query: 350 -----EPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQP 404
PP G S++ A AP P PPP+ + +S S P A
Sbjct: 583 LQAPRRPPTPGPDTSVSG------PRLTLALAPGPPPPPSRSPSSTL---SGPDLAGHSS 633
Query: 405 GHKRTPSE 412
TP E
Sbjct: 634 SATSTPEE 641
>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
Length = 748
Score = 68.9 bits (167), Expect = 1e-11
Identities = 61/201 (30%), Positives = 80/201 (39%), Gaps = 42/201 (20%)
Query: 406 HKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPA 465
H + + ++ +++ ++A Q Q QQQQQQQQQQQQQQQQA P PP QP P
Sbjct: 224 HHQNQQQIQQQQQQLQRIA--QLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPP 281
Query: 466 PVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGY------PPM----PRVPVVGITPSQM 515
P A P Q+ H QPP P P + PP P V P QM
Sbjct: 282 PS---QALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQM 338
Query: 516 VANA----FCSAAQLQPQP-----------ATLLGKAGAFPPPAIP-----------SAP 549
+ F A + QP A +A P + +P
Sbjct: 339 LYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSP 398
Query: 550 GSQARPRPNGAPWPPEPAPAP 570
G Q + P P PP+P+P P
Sbjct: 399 GQQVQT-PQSMPPPPQPSPQP 418
Score = 48.1 bits (113), Expect = 2e-05
Identities = 74/306 (24%), Positives = 93/306 (30%), Gaps = 109/306 (35%)
Query: 399 AAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQ------------------------ 434
AA Q ++ + + + Q +A QQQQQ
Sbjct: 175 AALQQQQQQQQQQQFQAQQSAMQQQFQAVVQQQQQLQQQQQQQQHLIKLHHQNQQQIQQQ 234
Query: 435 ----------------QQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVA 478
QQQQQQQQQQQQA P PP QP P P A P Q+
Sbjct: 235 QQQLQRIAQLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPP---PSQALPQQLQ 291
Query: 479 VFLPPPHMQPPFVPAYPGLG------------------------------YPPMP--RVP 506
H QPP P P + PP+ R P
Sbjct: 292 QMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAP 351
Query: 507 VVGITP-------SQMVANAFCSAAQL----------------QPQPATLLGKAGAFPPP 543
+V P Q A AAQ+ P P + + PPP
Sbjct: 352 MVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPP 411
Query: 544 AIPSAPGSQARPRPNG------APWPPE--PAPAPAPELDPFEA---QWAALEGKATVEK 592
PS Q +PN AP P P+P+P P P A Q ++ +
Sbjct: 412 PQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNT 471
Query: 593 PSNPFS 598
P NP S
Sbjct: 472 PVNPSS 477
Score = 47.4 bits (111), Expect = 4e-05
Identities = 43/111 (38%), Positives = 52/111 (46%), Gaps = 20/111 (18%)
Query: 354 AGDSDSINALCTQISSSFASAGAPAPGPPPATTGTS--------AWGEP-----SVPPAA 400
A SD +NAL Q + +AGA G PP G S A G+P PP
Sbjct: 76 ASVSDPMNAL--QSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGT 133
Query: 401 AFQPGHKRT--PSEAERWLEEVSQVAKAQQQQQQQQQQQQQ---QQQQQQQ 446
+ H + + ++ QVA QQQQQQQ QQQQQ QQQQQQQ
Sbjct: 134 SGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQ 184
Score = 36.6 bits (83), Expect = 0.069
Identities = 55/223 (24%), Positives = 76/223 (34%), Gaps = 47/223 (21%)
Query: 347 PEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPS-VPPAAAFQPG 405
P M+ P S ++ Q+ + P P PP A +PS +PP + QP
Sbjct: 273 PPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPV-----AQNQPSQLPPQSQTQPL 327
Query: 406 HKRTPSEAERWLEEV-------SQVAKAQQQQQQQQQQQQQQQQQQQQAASVAP------ 452
+ + + L + + Q Q Q QQQQ Q Q A VAP
Sbjct: 328 VSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQ 387
Query: 453 -----------------VPTMPPALQPFPAPVGPFDAAPAQV--------AVFLPPPHMQ 487
+MPP QP P P P + V + FLP P Q
Sbjct: 388 SSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSGPAPSPSSFLPSPSPQ 447
Query: 488 P---PFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQ 527
P P P P P + PS +++ A S A+ Q
Sbjct: 448 PSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQ 490
>gi|32307128 nuclear receptor coactivator 6 [Homo sapiens]
Length = 2063
Score = 67.4 bits (163), Expect = 4e-11
Identities = 67/221 (30%), Positives = 83/221 (37%), Gaps = 32/221 (14%)
Query: 393 EPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAP 452
+ S P + P H P R + + QQQQQQQQQQQQQQQQQQQQ
Sbjct: 228 QQSHPSGSLAPPHHPMQPVSVNRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQ 287
Query: 453 VPTMPPALQPFPAPVGPFDAAPAQVAV-----FLPPPHMQPPFVPAYPGLG----YPPMP 503
Q P + P AP QV V LP +QPP PA LG
Sbjct: 288 ARPPQQHQQQQPQGIRPQFTAPTQVPVPPGWNQLPSGALQPP--PAQGSLGTMTANQGWK 345
Query: 504 RVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWP 563
+ P+ G P Q QLQ +P+ + + PPP P QA P
Sbjct: 346 KAPLPG--PMQQ---------QLQARPSLATVQTPSHPPPPYPFG-SQQASQAHTNFPQM 393
Query: 564 PEPAPAPAPELD---------PFEAQWAALEGKATVEKPSN 595
P AP++ P Q L K+ PS+
Sbjct: 394 SNPGQFTAPQMKSLQGGPSRVPTPLQQPHLTNKSPASSPSS 434
Score = 42.4 bits (98), Expect = 0.001
Identities = 67/254 (26%), Positives = 94/254 (37%), Gaps = 44/254 (17%)
Query: 344 GTVPEMEPPG---AGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAA 400
G PE++P A SD+++ L + + S + + PP P P +
Sbjct: 198 GPNPELQPRTPRPASQSDAMDPLLSGLHIQQQSHPSGSLAPPH---------HPMQPVSV 248
Query: 401 AFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQ-------------QQQQQQQQQQQQA 447
Q P ++ ++ Q + QQQQQQQQ QQQ Q + Q A
Sbjct: 249 NRQMNPANFPQLQQQQQQQQQQQQQQQQQQQQQQQQQLQARPPQQHQQQQPQGIRPQFTA 308
Query: 448 ASVAPVP----TMPP-ALQPFPA--PVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYP 500
+ PVP +P ALQP PA +G A LP P Q + A P L
Sbjct: 309 PTQVPVPPGWNQLPSGALQPPPAQGSLGTMTANQGWKKAPLPGPMQQQ--LQARPSLATV 366
Query: 501 PMPRVPVVGIT-PSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQAR-PRPN 558
P P SQ + A + Q + G F P + S G +R P P
Sbjct: 367 QTPSHPPPPYPFGSQQASQAHTNFPQ--------MSNPGQFTAPQMKSLQGGPSRVPTPL 418
Query: 559 GAPWPPEPAPAPAP 572
P +PA +P
Sbjct: 419 QQPHLTNKSPASSP 432
Score = 41.2 bits (95), Expect = 0.003
Identities = 66/255 (25%), Positives = 91/255 (35%), Gaps = 50/255 (19%)
Query: 377 PAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEV---------------S 421
P PG S P +P + PG+ P E +R L+++
Sbjct: 947 PLPGEQGINLDNSG---PKLPEFSNRPPGYPSQPVE-QRPLQQMPPQLMQHVAPPPQPPQ 1002
Query: 422 QVAKAQQQQQQQ-----QQQQQQQQQQQQQAASVAPVPTMP-----PALQPFPAPVGPFD 471
Q + Q QQQQ Q Q QQQQQQQQQ + + P P Q P GP +
Sbjct: 1003 QQPQPQLPQQQQPPPPSQPQSQQQQQQQQQMMMMLMMQQDPKSVRLPVSQNVHPPRGPLN 1062
Query: 472 ----AAPAQVAVFLP--PPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQ 525
P Q + +P P VP P PMP +G +MV +
Sbjct: 1063 PDSQRMPMQQSGSVPVMVSLQGPASVPPSPDKQRMPMPVNTPLGSNSRKMV----YQESP 1118
Query: 526 LQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPEL-----DPFEAQ 580
P + L A ++P A GS+A P G P P +L P +
Sbjct: 1119 QNPSSSPLAEMA------SLPEASGSEAPSVPGGPNNMPSHVVLPQNQLMMTGPKPGPSP 1172
Query: 581 WAALEGKATVEKPSN 595
+A +G + P N
Sbjct: 1173 LSATQGATPQQPPVN 1187
>gi|55956910 meningioma 1 [Homo sapiens]
Length = 1320
Score = 66.6 bits (161), Expect = 6e-11
Identities = 98/360 (27%), Positives = 133/360 (36%), Gaps = 55/360 (15%)
Query: 236 REAPDKKKAEAAAAPTVAPGPAQPGHV----SPTPATTSPGEKGEAGTPVAAGTTAAA-I 290
++AP + + P P PG + S PA P ++GEAGTP +
Sbjct: 342 QQAPPPPQQQPPQQPPQQQPPPPPGLLVRQNSCPPALPRP-QQGEAGTPSGGLQDGGPML 400
Query: 291 PRRHAPLEQLVRQGSFRGF-----PALSQKNSPFKRQLSLRLNELPS----TLQRRTDFQ 341
P +HA E + + R P S ++ P ++ + RL + + +R F
Sbjct: 401 PSQHAQFEYPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDAPPYMNVAKRPRFD 460
Query: 342 VKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAA 401
G+ S AL +S S A G P PP PS PP
Sbjct: 461 FPGSAGVDRCASWNGSMHNGALDNHLSPS-AYPGLPGEFTPPVPDSF-----PSGPPLQH 514
Query: 402 FQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPP--- 458
P H+ L++ Q + QQQQQQQQQQQQQQQQQQQ+ + + M
Sbjct: 515 PAPDHQS--------LQQQQQQQQQQQQQQQQQQQQQQQQQQQQRQNAALMIKQMASRNQ 566
Query: 459 ---ALQPFPAPVG-PFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQ 514
QP A +G P D + H P GL P R G T +
Sbjct: 567 QQRLRQPNLAQLGHPGDVGQGGLV------HGGP-----VGGLAQPNFEREG--GSTGAG 613
Query: 515 MVANAFCSAAQLQPQPATLLGKAGAFPPPA--IPSAPGSQARPRPNGAPWPPEPAPAPAP 572
+ A L + A +G PPP +P G P G P P AP P P
Sbjct: 614 RLGTFEQQAPHLAQESAWF---SGPHPPPGDLLPRRMGGSGLPADCG-PHDPSLAPPPPP 669
Score = 55.8 bits (133), Expect = 1e-07
Identities = 88/339 (25%), Positives = 112/339 (33%), Gaps = 72/339 (21%)
Query: 263 SPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLV-RQGSFRGFPALSQKNSPFKR 321
S P + P G ++G ++ A+P PL+Q R SF G P+ S +S
Sbjct: 159 SQGPESFGPQRPGNLPDFHSSGASSHAVPAPCLPLDQSPNRAASFHGLPSSSGSDSH--- 215
Query: 322 QLSLRLNELPSTLQRRTDFQVKGTVPEMEPPG---AGDSDSINALCTQISSSFASAGAPA 378
S RR Q E PG +G D + ++ +AG
Sbjct: 216 ----------SLEPRRVTNQGAVDSLEYNYPGEAPSGHFDMFSPSDSEGQLPHYAAGRQV 265
Query: 379 PGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQ 438
PG A+ S P AA G + AQ QQQ QQQQQ
Sbjct: 266 PG--------GAFPGASAMPRAAGMVGLSKM---------------HAQPPQQQPQQQQQ 302
Query: 439 QQQQQQQQAA---SVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYP 495
QQQQQQ + MP L+P P P Q PPP QP P P
Sbjct: 303 PQQQQQQHGVFFERFSGARKMPVGLEPSVGSRHPLMQPPQQAP---PPPQQQP---PQQP 356
Query: 496 GLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPP--PAIPSAPGSQA 553
PP P P +V C A +PQ +G P +PS
Sbjct: 357 PQQQPPPP--------PGLLVRQNSCPPALPRPQQGEAGTPSGGLQDGGPMLPSQHAQFE 408
Query: 554 RP-------------RPNGAPWPPEPAPAPAPELDPFEA 579
P P + P P AP L F+A
Sbjct: 409 YPIHRLENRSMHPYSEPVFSMQHPPPQQAPNQRLQHFDA 447
>gi|56549696 E1A binding protein p400 [Homo sapiens]
Length = 3122
Score = 66.2 bits (160), Expect = 8e-11
Identities = 93/336 (27%), Positives = 124/336 (36%), Gaps = 38/336 (11%)
Query: 233 PAEREAPDKKKAEAAAA------PTVAPGPAQPGHVSP----TPATTSPGEKGEAGTPVA 282
P ++ P + +AA + P V P P P PA P V
Sbjct: 2516 PPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQAPAKAQPAITTGGSAAVL 2575
Query: 283 AGTTAAAIPRRHAPLEQL---VRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTD 339
AGT ++ P + V + G PA + + S KR S +T
Sbjct: 2576 AGTIKTSVTGTSMPTGAVSGNVIVNTIAGVPAATFQ-SINKRLASPVAPGALTTPGGSAP 2634
Query: 340 FQVKGTVPE---MEPPGAGDSDSINALCTQ----ISSSFASAGAPAPGPPPATTGTSAWG 392
QV T P + P D ++ TQ ++S ASA P T S
Sbjct: 2635 AQVVHTQPPPRAVGSPATATPDLVSMATTQGVRAVTSVTASAVVTTNLTPVQTPARSL-- 2692
Query: 393 EPSVPPAAAFQ-PGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVA 451
P V A Q PG TP+ + ++ Q + QQQQQQQQQQQQQQQQQQQQ + +
Sbjct: 2693 VPQVSQATGVQLPGKTITPAHFQLLRQQQQQQQQQQQQQQQQQQQQQQQQQQQQQTTTTS 2752
Query: 452 PVPTMPPALQPFPAPVGPFDAAPAQVAVF--LPPPHMQPPFVPAYPGLGYPPMPRVPVVG 509
V P +Q +PAQ+ L P H+ L PP P P
Sbjct: 2753 QVQV--PQIQGQA-------QSPAQIKAVGKLTPEHL---IKMQKQKLQMPPQPPPPQAQ 2800
Query: 510 ITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAI 545
P Q A +Q Q + L A P A+
Sbjct: 2801 SAPPQPTAQVQVQTSQPPQQQSPQLTTVTAPRPGAL 2836
Score = 42.0 bits (97), Expect = 0.002
Identities = 49/186 (26%), Positives = 71/186 (38%), Gaps = 32/186 (17%)
Query: 397 PPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASV-APVPT 455
P A A P + P+ A+ + Q A+ Q+Q QQQ Q AAS+ P+P
Sbjct: 497 PGADAGVPLQQLMPT-AQGGMPPTPQAAQLAGQRQSQQQYDPSTGPPVQNAASLHTPLPQ 555
Query: 456 MPPALQPFPAPVGPFDAA----------PAQVAVFLPPPHMQPPF-VPAYPGLGYPPMPR 504
+P L P P +A AQ + +P QP +PA PP +
Sbjct: 556 LPGRLPPAGVPTAALSSALQFAQQPQVVEAQTQLQIPVKTQQPNVPIPA------PPSSQ 609
Query: 505 VPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPP 564
+P+ P+Q+ + P P + +A + S P A R P PP
Sbjct: 610 LPIPPSQPAQLALHV--------PTPGKVQVQAS-----QLSSLPQMVASTRLPVDPAPP 656
Query: 565 EPAPAP 570
P P P
Sbjct: 657 CPRPLP 662
Score = 37.4 bits (85), Expect = 0.040
Identities = 72/316 (22%), Positives = 99/316 (31%), Gaps = 81/316 (25%)
Query: 215 SRTSFAREGSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEK 274
S+ R+ +S PA R A K KA P V G G P+T P
Sbjct: 1394 SKKKIPRKLMEEISTSAAPAARPAAAKLKASRLFQP-VQYGQKPEGRTVAFPSTHPPR-- 1450
Query: 275 GEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTL 334
AA TTA+A P+ PL +F P +PF+
Sbjct: 1451 ------TAAPTTASAAPQ--GPLRGRPPIATFSANPEAKAAAAPFQTS------------ 1490
Query: 335 QRRTDFQVKGTVPEMEPPGAGDSDSINA----LCTQISSSFASAGAPAPGP--PPATTGT 388
Q + P +P A + + A L Q ++ ++ G P P P P G
Sbjct: 1491 ------QASASAPRHQPASASSTAASPAHPAKLRAQTTAQASTPGQPPPQPQAPSHAAGQ 1544
Query: 389 SAW-----------------------------------GEPSVPPAAAFQPGHKRTPSEA 413
SA +P P FQ G K T S +
Sbjct: 1545 SALPQRLVLPSQAQARLPSGEVVKIAQLASITGPQSRVAQPETPVTLQFQ-GSKFTLSHS 1603
Query: 414 E----------RWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPF 463
+ + V Q+ A Q + Q Q A + + PPA P
Sbjct: 1604 QLRQLTAGQPLQLQGSVLQIVSAPGQPYLRAPGPVVMQTVSQAGAVHGALGSKPPAGGPS 1663
Query: 464 PAPVGPFDAAPAQVAV 479
PAP+ P P +VAV
Sbjct: 1664 PAPLTPQVGVPGRVAV 1679
Score = 37.0 bits (84), Expect = 0.053
Identities = 68/270 (25%), Positives = 99/270 (36%), Gaps = 35/270 (12%)
Query: 230 GGRPAEREAPD---KKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTT 286
GG P +A +++++ P+ P P Q TP PG AG P AA ++
Sbjct: 514 GGMPPTPQAAQLAGQRQSQQQYDPSTGP-PVQNAASLHTPLPQLPGRLPPAGVPTAALSS 572
Query: 287 AAAIPRRHAPLEQLVRQGSFRGFPALSQK-NSPFKRQLSLRLNELPS-----TLQRRTDF 340
A + A Q+V + P +Q+ N P S +L PS L T
Sbjct: 573 AL----QFAQQPQVVEAQTQLQIPVKTQQPNVPIPAPPSSQLPIPPSQPAQLALHVPTPG 628
Query: 341 QVK------GTVPEMEPPGAGDSDSI----NALCTQISSSFASAGAPAPGPPPATTGTSA 390
+V+ ++P+M D L T +SS A PGP PA + S
Sbjct: 629 KVQVQASQLSSLPQMVASTRLPVDPAPPCPRPLPTSSTSSLAPVSGSGPGPSPARS--SP 686
Query: 391 WGEPSVPPAAAFQPGHKRTP---SEAERWLEEVSQVAKAQQQQQQQQQQQQ--QQQQQQQ 445
PS A P RTP + A + +Q A + Q Q +Q + Q Q
Sbjct: 687 VNRPSSATNKALSPVTSRTPGVVASAPTKPQSPAQNATSSQDSSQDTLTEQITLENQVHQ 746
Query: 446 QAASVAPVPTMP----PALQPFPAPVGPFD 471
+ A + P LQ P P +D
Sbjct: 747 RIAELRKAGLWSQRRLPKLQEAPRPKSHWD 776
Score = 35.4 bits (80), Expect = 0.15
Identities = 47/177 (26%), Positives = 60/177 (33%), Gaps = 65/177 (36%)
Query: 422 QVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFL 481
QVA + ++ ++++ QQ+ QQ P PP QP P
Sbjct: 2476 QVASLRAERIAKEKKALADQQKAQQ-----PAVAQPPPPQPQP----------------- 2513
Query: 482 PPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFP 541
PPP QPP PP+P QPQ A
Sbjct: 2514 PPPPQQPP----------PPLP-----------------------QPQ-------AAGSQ 2533
Query: 542 PPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEG--KATVEKPSNP 596
PPA P A Q +P+P P P + APA A A L G K +V S P
Sbjct: 2534 PPAGPPAVQPQPQPQPQTQPQPVQ-APAKAQPAITTGGSAAVLAGTIKTSVTGTSMP 2589
Score = 31.6 bits (70), Expect = 2.2
Identities = 27/84 (32%), Positives = 31/84 (36%), Gaps = 14/84 (16%)
Query: 413 AERWLEEVSQVAKAQQQQQQQQQQQQQQQQQ-------------QQQAASVAPVPTMPPA 459
AER +E +A Q+ QQ Q Q Q Q QAA P P PPA
Sbjct: 2482 AERIAKEKKALADQQKAQQPAVAQPPPPQPQPPPPPQQPPPPLPQPQAAGSQP-PAGPPA 2540
Query: 460 LQPFPAPVGPFDAAPAQVAVFLPP 483
+QP P P P Q P
Sbjct: 2541 VQPQPQPQPQTQPQPVQAPAKAQP 2564
Score = 30.8 bits (68), Expect = 3.8
Identities = 55/231 (23%), Positives = 70/231 (30%), Gaps = 36/231 (15%)
Query: 381 PPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQ----------- 429
P PA + SVP A PG P + Q KA Q
Sbjct: 2869 PQPAQVALAKPPVVSVPAAVVSSPGVTTLPMNVAGISVAIGQPQKAAGQTVVAQPVHMQQ 2928
Query: 430 -----QQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPP 484
QQ QQQ+ Q Q Q A+V T P + A PA FL P
Sbjct: 2929 LLKLKQQAVQQQKAIQPQAAQGPAAVQQKITAQQITTPGAQQKVAYAAQPALKTQFLTTP 2988
Query: 485 HMQPPFV----PAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQ-----PATLLG 535
Q + + +P+V V TP + ++ Q PQ AT G
Sbjct: 2989 ISQAQKLAGAQQVQTQIQVAKLPQV-VQQQTPVASIQQVASASQQASPQTVALTQATAAG 3047
Query: 536 KAGAFPPPAIPSAPGSQAR----------PRPNGAPWPPEPAPAPAPELDP 576
+ P +A Q + P P P PA PA P
Sbjct: 3048 QQVQMIPAVTATAQVVQQKLIQQQVVTTASAPLQTPGAPNPAQVPASSDSP 3098
Score = 30.4 bits (67), Expect = 4.9
Identities = 77/365 (21%), Positives = 120/365 (32%), Gaps = 61/365 (16%)
Query: 255 GPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRG--FPAL 312
G QP H +P P+ + P A + +A ++QL+ + G
Sbjct: 25 GEEQPAHPNPPPSPAA---------PFAPSASPSAPQSPSYQIQQLMNRSPATGQNVNIT 75
Query: 313 SQKNSPF---KRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISS 369
Q P +Q++L LPS FQ E + L Q+ +
Sbjct: 76 LQSVGPVVGGNQQITLAPLPLPSPTS--PGFQFSAQPRRFEHGSPSYIQVTSPLSQQVQT 133
Query: 370 SFASAGAPAPGPPPATTGTSAWGEP-------SVPPAAAFQPGH------KRTPSEAERW 416
S P+PGP A A G P S P F +PS +
Sbjct: 134 Q--SPTQPSPGPGQALQNVRA-GAPGPGLGLCSSSPTGGFVDASVLVRQISLSPSSGGHF 190
Query: 417 LEE----VSQVAKAQQQQQQQQ------QQQQQQQQQQQQAASVAPVPTMPPA------L 460
+ + ++Q+A+ Q Q Q ++++ Q Q ++ + PA L
Sbjct: 191 VFQDGSGLTQIAQGAQVQLQHPGTPITVRERRPSQPHTQSGGTIHHLGPQSPAAAGGAGL 250
Query: 461 QPFPAPVGPFDAAPAQVAVFLPPPH----MQPPFVPAYPGLGYPPMPRVPVVGITPSQMV 516
QP A+P+ + PP +Q V L PP+PR TP ++
Sbjct: 251 QPL--------ASPSHITTANLPPQISSIIQGQLVQQQQVLQGPPLPRPLGFERTPGVLL 302
Query: 517 ANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAP-GSQARPRPNGAPWPPEPAPAPAPELD 575
A +A P + PP + S P S P E P +PE+
Sbjct: 303 PGAGGAAGFGMTSPPPPTSPSRTAVPPGLSSLPLTSVGNTGMKKVPKKLEEIPPASPEMA 362
Query: 576 PFEAQ 580
Q
Sbjct: 363 QMRKQ 367
Score = 29.6 bits (65), Expect = 8.4
Identities = 26/103 (25%), Positives = 37/103 (35%), Gaps = 18/103 (17%)
Query: 491 VPAYPGLGYP-PMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAP 549
V A G+ Y P+P + V + ++ A Q + Q A A PPP P P
Sbjct: 2460 VLAESGINYDKPLPPIQVASLRAERIAKEKKALADQQKAQQ-----PAVAQPPPPQPQPP 2514
Query: 550 GSQARP------------RPNGAPWPPEPAPAPAPELDPFEAQ 580
+P +P P +P P P P+ P Q
Sbjct: 2515 PPPQQPPPPLPQPQAAGSQPPAGPPAVQPQPQPQPQTQPQPVQ 2557
>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
Length = 788
Score = 66.2 bits (160), Expect = 8e-11
Identities = 54/159 (33%), Positives = 70/159 (44%), Gaps = 24/159 (15%)
Query: 406 HKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPA 465
H + + ++ +++ ++A Q Q QQQQQQQQQQQQQQQQA P PP QP P
Sbjct: 224 HHQNQQQIQQQQQQLQRIA--QLQLQQQQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPP 281
Query: 466 PVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQ 525
P A P Q+ H QPP P P PV PSQ+ Q
Sbjct: 282 ---PSQALPQQLQQMHHTQHHQPPPQPQQP----------PVAQNQPSQL-------PPQ 321
Query: 526 LQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPP 564
Q QP L+ +A A P + + P + P PP
Sbjct: 322 SQTQP--LVSQAQALPGQMLYTQPPLKFVRAPMVVQQPP 358
Score = 47.4 bits (111), Expect = 4e-05
Identities = 43/111 (38%), Positives = 52/111 (46%), Gaps = 20/111 (18%)
Query: 354 AGDSDSINALCTQISSSFASAGAPAPGPPPATTGTS--------AWGEP-----SVPPAA 400
A SD +NAL Q + +AGA G PP G S A G+P PP
Sbjct: 76 ASVSDPMNAL--QSLTGGPAAGAAGIGMPPRGPGQSLGGMGSLGAMGQPMSLSGQPPPGT 133
Query: 401 AFQPGHKRT--PSEAERWLEEVSQVAKAQQQQQQQQQQQQQ---QQQQQQQ 446
+ H + + ++ QVA QQQQQQQ QQQQQ QQQQQQQ
Sbjct: 134 SGMAPHSMAVVSTATPQTQLQLQQVALQQQQQQQQFQQQQQAALQQQQQQQ 184
Score = 31.2 bits (69), Expect = 2.9
Identities = 30/118 (25%), Positives = 40/118 (33%), Gaps = 11/118 (9%)
Query: 421 SQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQV--- 477
S + +Q Q Q V +MPP QP P P P + V
Sbjct: 413 SSIPLGRQPMAQVSQSSLPMLSSPSPGQQVQTPQSMPPPPQPSPQPGQPSSQPNSNVSSG 472
Query: 478 -----AVFLPPPHMQP---PFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQ 527
+ FLP P QP P P P P + PS +++ A S A+ Q
Sbjct: 473 PAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPAGSSQAEEQ 530
Score = 30.0 bits (66), Expect = 6.5
Identities = 55/275 (20%), Positives = 98/275 (35%), Gaps = 38/275 (13%)
Query: 239 PDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPL- 297
P ++ + A A PG T A G A P T +AIP PL
Sbjct: 361 PQVQQQQTAVQTAQAAQMVAPGVQMITEALAQGGMHIRARFPPT--TAVSAIPSSSIPLG 418
Query: 298 EQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDS 357
Q + Q S P LS PS Q+ Q P+ P S
Sbjct: 419 RQPMAQVSQSSLPMLSS----------------PSPGQQVQTPQSMPPPPQPSPQPGQPS 462
Query: 358 DSINALCTQISSSFASAGAPAPGPPPATTGTSA-----WGEPS-------VPPAAAFQPG 405
N+ + + S+ P+P P P+ + +A + PS V P++ P
Sbjct: 463 SQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGPLNTPVNPSSVMSPA 522
Query: 406 HKRTPSEAERWLEEVSQVAKAQQQQQQ------QQQQQQQQQQQQQQAASVAPVPTMPPA 459
+ +E +++L+++ Q++K + ++ + + +++ + + + P+
Sbjct: 523 GS-SQAEEQQYLDKLKQLSKYIEPLRRMINKIDKNEDRKKDLSKMKSLLDILTDPSKRCP 581
Query: 460 LQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAY 494
L+ + +AV PPP PP Y
Sbjct: 582 LKTLQKCEIALEKLKNDMAVPTPPPPPVPPTKQQY 616
>gi|9945318 MAX binding protein [Homo sapiens]
Length = 582
Score = 65.9 bits (159), Expect = 1e-10
Identities = 58/211 (27%), Positives = 91/211 (43%), Gaps = 38/211 (18%)
Query: 412 EAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVA----------------PVPT 455
EA R+LE +Q + +++Q++ + +Q+++Q+Q++A S+A P+P
Sbjct: 8 EAARFLEWQAQQQQRAREEQERLRLEQEREQEQKKANSLARLAHTLPVEEPRMEAPPLPL 67
Query: 456 MPPALQPFPAPV----GPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGIT 511
PPA P P P P P V P P PP +PA P PR P +
Sbjct: 68 SPPAPPPAPPPPLATPAPLTVIPIPVVTNSPQPLPPPPPLPA-AAQPLPLAPRQPALVGA 126
Query: 512 PSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPA 571
P + +PA L + P PA P P S+A PNG+P P +P P P
Sbjct: 127 PGLSIK-----------EPAPLPSRPQV-PTPA-PLLPDSKATIPPNGSPKPLQPLPTPV 173
Query: 572 PELDPFEAQWAALEGKATVEKPSNPFSGDLQ 602
+ P ++ + ++P P G L+
Sbjct: 174 LTIAPH----PGVQPQLAPQQPPPPTLGTLK 200
>gi|149158690 HLA-B associated transcript-2 [Homo sapiens]
Length = 2157
Score = 65.9 bits (159), Expect = 1e-10
Identities = 108/383 (28%), Positives = 142/383 (37%), Gaps = 86/383 (22%)
Query: 238 APDKK-KAEAAAAP----TVAPGPAQPGHVSPTPA---TTSPGEKGEAGTPVAAGTTAAA 289
APDK+ KAE AA P T AP PA P + PA ++P + E P A +
Sbjct: 499 APDKRLKAEPAAPPAAPSTPAPPPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQST 558
Query: 290 IPRRHAPLEQLVRQG-SFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPE 348
A LV G S + S + SP + QL + P VP+
Sbjct: 559 PTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEGPEPP---EEVPPPTTPPVPK 615
Query: 349 MEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKR 408
+EP G G P PP G + + S+PP FQ
Sbjct: 616 VEPKGDGIG-------------------PTRQPPSQGLGYPKY-QKSLPPR--FQ----- 648
Query: 409 TPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVG 468
+ QQ+Q +QQQQ Q QQ QQ +A PVP PP P +G
Sbjct: 649 ----------------RQQQEQLLKQQQQHQWQQHQQGSAPPTPVPPSPPQ----PVTLG 688
Query: 469 PFDAAPAQVAVFLPPPHMQPPFVPAYPG-LGYPPMPRVPVVGITPSQMVANAFCSAAQLQ 527
A PA A PP PP YPG LG P P +P + P M+ + LQ
Sbjct: 689 ---AVPAPQA---PP----PPPKALYPGALGRP--PPMPPMNFDPRWMMIPPYVDPRLLQ 736
Query: 528 PQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPA-------PELDPFEAQ 580
+P +PP PS + R G+ P APA P +DP +
Sbjct: 737 GRP-----PLDFYPPGVHPSGLVPRERSDSGGSSSEPFDRHAPAMLRERGTPPVDP-KLA 790
Query: 581 WAALEGKATVEKPSNPFSGDLQK 603
W AT +P P + L++
Sbjct: 791 WVGDVFTATPAEP-RPLTSPLRQ 812
Score = 44.3 bits (103), Expect = 3e-04
Identities = 83/358 (23%), Positives = 113/358 (31%), Gaps = 63/358 (17%)
Query: 258 QPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNS 317
Q G PTP SP + PV G A P+ P + + G+ P + N
Sbjct: 668 QQGSAPPTPVPPSPPQ------PVTLGAVPA--PQAPPPPPKALYPGALGRPPPMPPMNF 719
Query: 318 PFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAP 377
R + + P LQ R + PPG S + + S S S+ P
Sbjct: 720 D-PRWMMIPPYVDPRLLQGRPPL-------DFYPPGVHPSGLVPR---ERSDSGGSSSEP 768
Query: 378 APGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQ 437
PA G P V P A W+ +V A+ + +Q
Sbjct: 769 FDRHAPAMLRER--GTPPVDPKLA--------------WVGDVFTATPAEPRPLTSPLRQ 812
Query: 438 QQQQQQQQQAASVAPVPTMPPALQPFP------APVGPFDAAPAQVAVFLPPPHMQPPFV 491
+ + + PVP PP L +P AP P P + P P PP
Sbjct: 813 AADEDDKGMRSETPPVPPPPPYLASYPGFPENGAPGPPISRFPLEEPG--PRPLPWPPGS 870
Query: 492 PAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSA--- 548
+ PP + P P + A + + +PA +G G PPP +
Sbjct: 871 DEVAKIQTPPPKKEP-----PKEETAQ--LTGPEAGRKPARGVGSGGQGPPPPRRESRTE 923
Query: 549 ------PGSQARPRPNGAPWPPE----PAPAPAPELDPFEAQWAALEGKATVEKPSNP 596
PGS R P P P P P P E LE KP P
Sbjct: 924 TRWGPRPGSSRRGIPPEEPGAPPRRAGPIKKPPPPTKVEELPPKPLEQGDETPKPPKP 981
Score = 41.6 bits (96), Expect = 0.002
Identities = 51/248 (20%), Positives = 85/248 (34%), Gaps = 57/248 (22%)
Query: 347 PEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGH 406
P + PP G + + + G P PP AW
Sbjct: 410 PPLPPPHRGPAGNWGP-----PGDYPDRGGPPCKPPAPEDEDEAW--------------- 449
Query: 407 KRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPV------------- 453
+R + S+++ A ++ ++++++++++ Q++++AA +
Sbjct: 450 ------RQRRKQSSSEISLAVERARRRREEEERRMQEERRAACAEKLKRLDEKFGAPDKR 503
Query: 454 ----PTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVG 509
P PPA PAP P V LP P PP P + P
Sbjct: 504 LKAEPAAPPAAPSTPAP-------PPAVPKELPAPPAPPPASAPTPETEPEEPAQAPPAQ 556
Query: 510 ITPSQMVANAFCSAAQLQPQPATLLGKAGAFP-PPAIPSAPGSQARPRPNGAPWPPEPAP 568
TP+ VA A + +T G A P P +PS G P P P
Sbjct: 557 STPTPGVAAAPTLVSGGGSTSSTSSGSFEASPVEPQLPSKEG------PEPPEEVPPPTT 610
Query: 569 APAPELDP 576
P P+++P
Sbjct: 611 PPVPKVEP 618
Score = 37.0 bits (84), Expect = 0.053
Identities = 86/365 (23%), Positives = 120/365 (32%), Gaps = 52/365 (14%)
Query: 221 REGSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTP 280
RE + R S G A EA TVAP P + SP + + + E
Sbjct: 1264 RENAARGSEGKPSLTLPASAPGPEEALTTVTVAPAPRRAAAKSPDLSNQNSDQANEEWET 1323
Query: 281 VAAGTTAAAIPR--RHAPLEQLVRQ-----------GSFRGFPALSQKNSPFKRQLSLRL 327
+ + + R + AP L+ G+ G A+S + LS R
Sbjct: 1324 ASESSDFTSERRGDKEAPPPVLLTPKAVGTPGGGGGGAVPGISAMS------RGDLSQRA 1377
Query: 328 NELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTG 387
+L +R Q G + PG G + SSS G P P
Sbjct: 1378 KDLS---KRSFSSQRPGMERQNRRPGPGGKAGSSG-----SSSGGGGGGPGGRTGPGRGD 1429
Query: 388 TSAWGEP---SVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQ 444
+W P S PP P + + + QV + QQ Q +Q
Sbjct: 1430 KRSWPSPKNRSRPPEERPPGLPLPPPPPSSSAVFRLDQVIHSNPAGIQQALAQLSSRQGS 1489
Query: 445 QQAASVAP--VPTMPPALQPFPAPVGPFDAAPAQVAVFL-PPPHMQPPFVPAYPGLGYPP 501
A P P +P A Q P+P P P +V L PH + P P G+G P
Sbjct: 1490 VTAPGGHPRHKPGLPQAPQG-PSPRPPTRYEPQRVNSGLSSDPHFEEP-GPMVRGVGGTP 1547
Query: 502 MPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPP-------AIPSAPGSQAR 554
V P + + P+ LL + + PPP + P PG QA
Sbjct: 1548 RDSAGVSPFPPKR---------RERPPRKPELL-QEESLPPPHSSGFLGSKPEGPGPQAE 1597
Query: 555 PRPNG 559
R G
Sbjct: 1598 SRDTG 1602
Score = 35.8 bits (81), Expect = 0.12
Identities = 80/379 (21%), Positives = 121/379 (31%), Gaps = 52/379 (13%)
Query: 224 SFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPT-----PATTSPGEKGEAG 278
S R GGGRP + P + AP P P P P SP +G +
Sbjct: 1168 SRRGRGGGRPPPQVCPGWSPPAKSLAPKKPPTGPLPPSKEPLKEKLIPGPLSPVARGGSN 1227
Query: 279 TPVAAGTTAAAIPRR--HAPLEQLVRQGSFRGFPALSQ---KNSPFKRQLSLRLNELPST 333
G PRR H +Q + FR + + S K L+L + P
Sbjct: 1228 GGSNVGMEDGERPRRRRHGRAQQQDKPPRFRRLKQERENAARGSEGKPSLTLPASA-PGP 1286
Query: 334 LQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAP----------GPPP 383
+ T V P A D N Q + + +A + PPP
Sbjct: 1287 EEALTTVTV---APAPRRAAAKSPDLSNQNSDQANEEWETASESSDFTSERRGDKEAPPP 1343
Query: 384 ATTGTSAWGEP------SVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQ 437
A G P +VP +A G ++SQ AK ++ Q+
Sbjct: 1344 VLLTPKAVGTPGGGGGGAVPGISAMSRG-------------DLSQRAKDLSKRSFSSQRP 1390
Query: 438 QQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGL 497
++Q ++ + + P G + P + P PGL
Sbjct: 1391 GMERQNRRPGPGGKAGSSGSSSGGGGGGPGGRTGPGRGDKRSWPSPKNRSRPPEERPPGL 1450
Query: 498 GYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRP 557
PP P Q++ + + A +Q A L + G+ +APG R +P
Sbjct: 1451 PLPPPPPSSSAVFRLDQVIHS---NPAGIQQALAQLSSRQGSV------TAPGGHPRHKP 1501
Query: 558 NGAPWPPEPAPAPAPELDP 576
P P+P P +P
Sbjct: 1502 GLPQAPQGPSPRPPTRYEP 1520
Score = 32.0 bits (71), Expect = 1.7
Identities = 89/370 (24%), Positives = 119/370 (32%), Gaps = 39/370 (10%)
Query: 230 GGRPAEREAP---DKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGE---KGEAGTPVAA 283
G P R P D + E + PGP T T PG G PV
Sbjct: 1703 GSEPPRRPPPAPHDGDRKELPREQPLPPGPIGTERSQRTDRGTEPGPIRPSHRPGPPVQF 1762
Query: 284 GTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVK 343
GT+ R + L + + A + P R L + S + +
Sbjct: 1763 GTSDKDSDLRLVVGDSLKAE---KELTASVTEAIPVSRDWELLPSAAASAEPQSKNLDSG 1819
Query: 344 GTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAA-- 401
VPE G + SSS S GA P + G G PS+ P +
Sbjct: 1820 HCVPEPSSSGQRLYPEVFYGSAGPSSSQISGGAMDSQLHPNSGGFRP-GTPSLHPYRSQP 1878
Query: 402 -FQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVA-PVPTM--P 457
+ P PS L A + Q Q + + A V P P+
Sbjct: 1879 LYLPPGPAPPSALLSGL--------ALKGQFLDFSTMQATELGKLPAGGVLYPPPSFLYS 1930
Query: 458 PALQPFPAPVGPFDAAPAQVAVFLPPPH------MQPPFVPAYPGLGYPPMPRVPVVGIT 511
PA P P P D + QV LP P +QP + G P + + +
Sbjct: 1931 PAFCPSPLP----DTSLLQVRQDLPSPSDFYSTPLQPGGQSGFLPSGAPAQQML--LPMV 1984
Query: 512 PSQMVANAFCS---AAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAP 568
SQ+ F S A P P +LL A PP++ P R +P P PA
Sbjct: 1985 DSQLPVVNFGSLPPAPPPAPPPLSLLPVGPALQPPSLAVRPPPAPATRVLPSPARPFPAS 2044
Query: 569 APAPELDPFE 578
EL P E
Sbjct: 2045 LGRAELHPVE 2054
Score = 29.6 bits (65), Expect = 8.4
Identities = 35/134 (26%), Positives = 51/134 (38%), Gaps = 15/134 (11%)
Query: 446 QAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQP--PFVPAYPGLGYPPMP 503
Q S+A P PA + P+P PF A+ + L P ++P + LG P
Sbjct: 2017 QPPSLAVRPPPAPATRVLPSPARPFPASLGRAE--LHPVELKPFQDYQKLSSNLGGPGSS 2074
Query: 504 RVPVVGIT----PSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNG 559
R P G + S++ A + + Q L +A PP A+ P R P
Sbjct: 2075 RTPPTGRSFSGLNSRLKATPSTYSGVFRTQRVDLYQQAS--PPDALRWIPKPWERTGP-- 2130
Query: 560 APWPPEPAPAPAPE 573
PP P+ E
Sbjct: 2131 ---PPREGPSRRAE 2141
>gi|47132519 Ras association and pleckstrin homology domains 1
isoform 1 [Homo sapiens]
Length = 1250
Score = 65.9 bits (159), Expect = 1e-10
Identities = 74/274 (27%), Positives = 102/274 (37%), Gaps = 47/274 (17%)
Query: 346 VPEMEPPGAGDSDSI---NALCTQISSSFASAGAP-APGPPPATTGTSAWGEPSVPPAAA 401
+P P AG + + + T++ ++ +GA P PP S + VPP
Sbjct: 649 LPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVPPNGV 708
Query: 402 FQPGHKRTPSEAE-RWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPAL 460
P P + ++ A Q + Q Q VAP PT PP
Sbjct: 709 VPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKIHQVQHITQVAP-PTPPPP- 766
Query: 461 QPFPAPVGPFDAAPAQVAVFLP----------------PPHMQPPFVPA-----YPGLGY 499
P PAP+ P AP + V +P PP PP PA +P
Sbjct: 767 PPIPAPLPP--QAPPKPLVTIPAPTSTKTVAPVVTQAAPPTPTPPVPPAKKQPAFPASYI 824
Query: 500 PPMPRVPVVGITPSQMVAN-AFCSA---AQLQPQPATLLGKAGAFPPPAIPSAPGSQ-AR 554
PP P P V + P + +FC+ + L P P+ + A FPPP P A SQ +
Sbjct: 825 PPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAMESQPLK 884
Query: 555 PRP-NGAP-----------WPPEPAPAPAPELDP 576
P P N AP W P P P+P+ P
Sbjct: 885 PVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPP 918
Score = 55.5 bits (132), Expect = 1e-07
Identities = 58/216 (26%), Positives = 87/216 (40%), Gaps = 29/216 (13%)
Query: 365 TQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQP-GHKRTPSEAERWLEEVSQV 423
T +SSS +G+ + P + + S + V QP GH R+ S S
Sbjct: 527 TSLSSSSIKSGSSSSSIPESQSNHSNQSDSGVSDT---QPAGHVRSQSIVS------SVF 577
Query: 424 AKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPP 483
++A ++ Q ++ + + + + P ++ P L P P V P+ A+ Q + LPP
Sbjct: 578 SEAWKRGTQLEESSKARMESMNR-----PYTSLVPPLSPQPKIVTPYTAS--QPSPPLPP 630
Query: 484 PHMQPPFVPAYPGLGYPPMPR--VPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFP 541
P PP P P PP+P P G V + + Q Q + L F
Sbjct: 631 PPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGAL-----FK 685
Query: 542 PPAIPSAPGSQARPR----PNGA-PWPPEPAPAPAP 572
PP P +P+ PNG P PP P P P P
Sbjct: 686 PPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTP 721
Score = 50.1 bits (118), Expect = 6e-06
Identities = 63/234 (26%), Positives = 75/234 (32%), Gaps = 51/234 (21%)
Query: 373 SAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQ 432
+A P+P PP P PP + A + S + + Q Q
Sbjct: 620 TASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQH 679
Query: 433 Q-----------QQQQQQQQQQQQQAASVAPVPTMPP--------ALQPFPAPVGP---- 469
Q Q + Q V P P PP Q PAP P
Sbjct: 680 SGALFKPPTPPVMQSQSVKPQILVPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQ 739
Query: 470 FDAAP-----------AQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVAN 518
F A P QVA PPP PP +PA PP P V + T ++ VA
Sbjct: 740 FSAPPPPLKIHQVQHITQVAPPTPPP---PPPIPAPLPPQAPPKPLVTIPAPTSTKTVAP 796
Query: 519 AFCSAAQLQPQPATLLGKAGAFPPPA--IPSAPGSQARPRPNGAPWPPEPAPAP 570
AA P P PPA P+ P S P P P PP P P P
Sbjct: 797 VVTQAAPPTPTPPV---------PPAKKQPAFPASYIPPSP---PTPPVPVPPP 838
Score = 38.9 bits (89), Expect = 0.014
Identities = 74/320 (23%), Positives = 100/320 (31%), Gaps = 55/320 (17%)
Query: 248 AAPTVAPGPAQPG----HVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQ 303
A PT P P P P P T P VA T AA P P+ +Q
Sbjct: 759 APPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTK--TVAPVVTQAAPPTPTPPVPPAKKQ 816
Query: 304 GSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINAL 363
+F PA SP + + P TL ++ F K + P + ++
Sbjct: 817 PAF---PASYIPPSPPTPPVPVP----PPTLPKQQSFCAKPPPSPLSP--------VPSV 861
Query: 364 CTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQV 423
QI+S F PPP T PPA QP K P+ +
Sbjct: 862 VKQIASQF---------PPPPT-----------PPAMESQP-LKPVPANVA---PQSPPA 897
Query: 424 AKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPP 483
KA+ + Q S P PP+ P P P P A+P P
Sbjct: 898 VKAKPKWQPSSIPVPSPDFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPG 957
Query: 484 PHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPP 543
P G PP P+ + A +P+ ++ F PP
Sbjct: 958 KKTSKTSSPG--GKKPPPTPQ--------RNSSIKSSSGAEHPEPKRPSVDSLVSKFTPP 1007
Query: 544 AIPSAPGSQARPRPNGAPWP 563
A +P + P P P P
Sbjct: 1008 AESGSPSKETLPPPAAPPKP 1027
Score = 33.5 bits (75), Expect = 0.58
Identities = 76/389 (19%), Positives = 123/389 (31%), Gaps = 79/389 (20%)
Query: 239 PDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLE 298
P KK A A + P P P P P T P ++ P P +P+
Sbjct: 811 PPAKKQPAFPASYIPPSPPTPP--VPVPPPTLPKQQSFCAKPP---------PSPLSPVP 859
Query: 299 QLVRQGSFRGFPALS---QKNSPFKRQLSLRLNELPSTLQRRTDFQ---VKGTVPEMEPP 352
+V+Q + + P + ++ P K + + P ++ + +Q + P+ PP
Sbjct: 860 SVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPP 919
Query: 353 GAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSE 412
S L P P PP A+ G P + PG K+ P
Sbjct: 920 PPESS-----LVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPT 974
Query: 413 AERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDA 472
+R + + + P P P +
Sbjct: 975 PQR------------------------NSSIKSSSGAEHPEPKRP--------------S 996
Query: 473 APAQVAVFLPPPHMQPPFVPAYPGLGYPPMP-RVPVVGITPSQMVANAFCSAAQLQPQPA 531
+ V+ F PP P P PP P ++ + G+ ++ SA A
Sbjct: 997 VDSLVSKFTPPAESGSPSKETLPPPAAPPKPGKLNLSGVNLPGVLQQGCVSA------KA 1050
Query: 532 TLLGKAGAFPPPAIPSAPGSQARPRP---NGAPWPPEPAPA-----PAPE---LDPFEAQ 580
+L G PS P P P P PP PA +P+ ++P Q
Sbjct: 1051 PVLSGRGKDSVVEFPSPPSDSDFPPPPPETELPLPPIEIPAVFSGNTSPKVAVVNPQPQQ 1110
Query: 581 WAALEGKATVEKPSNPFSGDLQKTFEIEL 609
W+ + K P+ P D + + E+
Sbjct: 1111 WSKMSVK-KAPPPTRPKRNDSTRLTQAEI 1138
Score = 33.1 bits (74), Expect = 0.76
Identities = 20/63 (31%), Positives = 24/63 (38%), Gaps = 11/63 (17%)
Query: 526 LQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALE 585
L PQP + + P P +P P P PP P P P P P +Q A
Sbjct: 609 LSPQPKIVTPYTASQPSPPLPPPP-----------PPPPPPPPPPPPPPPPLPSQSAPSA 657
Query: 586 GKA 588
G A
Sbjct: 658 GSA 660
>gi|119943102 CREB binding protein isoform b [Homo sapiens]
Length = 2404
Score = 65.5 bits (158), Expect = 1e-10
Identities = 96/387 (24%), Positives = 138/387 (35%), Gaps = 57/387 (14%)
Query: 233 PAEREAPDKKKAEAAAAPTVAPGPAQPGHV---SPTPATTSPGEKGEAGTPVAAGTTAAA 289
P P + P++ PG Q + P P P +A VA +
Sbjct: 1959 PVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSV 2018
Query: 290 IPRRH---APLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNE-----LPSTLQRRTDFQ 341
P R + L+ L+R L +SP ++Q L + + + + +++RT
Sbjct: 2019 QPPRSISPSALQDLLR--------TLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKY 2070
Query: 342 VKGTVPEMEP-------PGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEP 394
V P M+P PG ++ + + + AG P PG PP P
Sbjct: 2071 VANQ-PGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLN-P 2128
Query: 395 SVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVP 454
PGH + E+ + QQQQQQQQQQQQQQQQQQ A +
Sbjct: 2129 QGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGM- 2187
Query: 455 TMPPALQPFPAPVGPFDAAPA-----QVAVFLP---------PPHMQPPFVPAYPGLGYP 500
F P GP PA ++ LP M PGLG
Sbjct: 2188 ---AGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGAD 2244
Query: 501 PMPRVPVV---GITPSQMVANAFCSAAQ---LQPQPATLLG--KAGAFPPPAIPSAPGSQ 552
P + I Q + S Q + PQ L G +A P I ++ +Q
Sbjct: 2245 STPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQ 2304
Query: 553 AR-PRPNGAPWPPEPAP--APAPELDP 576
R P P +P P P +P+P + P
Sbjct: 2305 VRSPAPVQSPRPQSQPPHSSPSPRIQP 2331
Score = 39.7 bits (91), Expect = 0.008
Identities = 44/162 (27%), Positives = 59/162 (36%), Gaps = 18/162 (11%)
Query: 446 QAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLP---PPHMQPPFVPAYP--GLGYP 500
QA+ + P L P P P P+ P PP P P+ P G
Sbjct: 801 QASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQT 860
Query: 501 PMPR---VPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRP 557
P P VP T S A + AQ+ PQP T + PP++ + SQ +P P
Sbjct: 861 PTPTPGSVPSATQTQSTPTVQA-AAQAQVTPQPQTPV------QPPSVATPQSSQQQPTP 913
Query: 558 NGAPWPPEPAPAPAPELD---PFEAQWAALEGKATVEKPSNP 596
A P P A +D P + A+ E + P P
Sbjct: 914 VHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVP 955
Score = 37.4 bits (85), Expect = 0.040
Identities = 44/182 (24%), Positives = 66/182 (36%), Gaps = 26/182 (14%)
Query: 425 KAQQQQQQQQQQQQQQQQQQQQAASVAPVP--TMPPALQPFPAPVGPFDAAPAQVAVFLP 482
K +QQQ Q + QQ Q +++ + VP ++P P AP G P+ P
Sbjct: 1811 KLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLP---SPTSAPPGTPTQQPSTPQTPQP 1867
Query: 483 PPHMQPPFVPAYPGLGYPPMPRV-PVVGITPSQMVANAFCSAAQLQPQPATL-------- 533
P QP V P G+P + R P ++ + + QP PA +
Sbjct: 1868 PAQPQPSPVSMSPA-GFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIER 1926
Query: 534 ----------LGKAGAFPPPAIP-SAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWA 582
+ + PP PGSQ P P P + + P + P + Q A
Sbjct: 1927 EAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQA 1986
Query: 583 AL 584
L
Sbjct: 1987 PL 1988
Score = 37.4 bits (85), Expect = 0.040
Identities = 54/247 (21%), Positives = 84/247 (34%), Gaps = 33/247 (13%)
Query: 233 PAEREAPDKKKAEAAAAPTVAPGPAQP--GHVSPTPATTSPGEKGEAGTPVAAGTTAAAI 290
P+ AP + + P PAQP VS +PA + + T V+ G + +
Sbjct: 1845 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQV 1904
Query: 291 PRRHAP-------------LEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNEL-PSTLQR 336
P P +E+ +Q ++ P + + +++ P +L
Sbjct: 1905 PAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNV 1964
Query: 337 RTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSV 396
QV G V PPG Q + P PG P A +
Sbjct: 1965 PRPNQVSGPVMPSMPPG------------QWQQAPLPQQQPMPGLPRPVISMQAQAAVAG 2012
Query: 397 PPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQ-----QQQQQQQQQQQQQQQAASVA 451
P + QP +PS + L + + QQQQQ + Q +Q+ A VA
Sbjct: 2013 PRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVA 2072
Query: 452 PVPTMPP 458
P M P
Sbjct: 2073 NQPGMQP 2079
Score = 36.6 bits (83), Expect = 0.069
Identities = 40/202 (19%), Positives = 74/202 (36%), Gaps = 27/202 (13%)
Query: 251 TVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFP 310
T PG P +PT +T G+ TP G+ +A + P Q Q
Sbjct: 834 TTPPGMTPPQPAAPTQPSTPVSSSGQTPTP-TPGSVPSATQTQSTPTVQAAAQAQ----- 887
Query: 311 ALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQI--S 368
Q +P + P ++ Q + T +PPG S + ++ ++
Sbjct: 888 VTPQPQTPVQ----------PPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTP 937
Query: 369 SSFASAGA----PAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVA 424
SS ASA P P P T E + P PG + +E E++ +
Sbjct: 938 SSVASAETNSQQPGPDVPVLEMKTETQAEDTEP-----DPGESKGEPRSEMMEEDLQGAS 992
Query: 425 KAQQQQQQQQQQQQQQQQQQQQ 446
+ +++ +Q+ + + +++
Sbjct: 993 QVKEETDIAEQKSEPMEVDEKK 1014
Score = 35.4 bits (80), Expect = 0.15
Identities = 37/151 (24%), Positives = 50/151 (33%), Gaps = 19/151 (12%)
Query: 432 QQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFV 491
Q Q Q Q AA P+ + P P P V P H PP
Sbjct: 774 QPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCP-----------PVTQSPLHPTPP-- 820
Query: 492 PAYPGLGYPPMPRVPVVGITPSQMVA-----NAFCSAAQLQ-PQPATLLGKAGAFPPPAI 545
PA G P + G+TP Q A S+ Q P P ++ P +
Sbjct: 821 PASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTV 880
Query: 546 PSAPGSQARPRPNGAPWPPEPAPAPAPELDP 576
+A +Q P+P PP A + + P
Sbjct: 881 QAAAQAQVTPQPQTPVQPPSVATPQSSQQQP 911
Score = 29.6 bits (65), Expect = 8.4
Identities = 41/200 (20%), Positives = 70/200 (35%), Gaps = 21/200 (10%)
Query: 418 EEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQV 477
E++ ++ K +++++ + +Q Q + P + P QP P GP ++
Sbjct: 618 EKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRM 677
Query: 478 AV------FLPPP--HMQPPFVPAYPGLGYP--------PMPRVPVVGITPSQMVANAFC 521
V F P ++Q P P P P M VP + I+PS+M
Sbjct: 678 QVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNM 737
Query: 522 SAAQLQPQPATLLGKAGAFPPPAIPSAPGSQA-----RPRPNGAPWPPEPAPAPAPELDP 576
A A ++ P PS+ G+ + P G P A L+
Sbjct: 738 MGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNM 797
Query: 577 FEAQWAALEGKATVEKPSNP 596
Q + L + P +P
Sbjct: 798 LGPQASQLPCPPVTQSPLHP 817
>gi|119943104 CREB binding protein isoform a [Homo sapiens]
Length = 2442
Score = 65.5 bits (158), Expect = 1e-10
Identities = 96/387 (24%), Positives = 138/387 (35%), Gaps = 57/387 (14%)
Query: 233 PAEREAPDKKKAEAAAAPTVAPGPAQPGHV---SPTPATTSPGEKGEAGTPVAAGTTAAA 289
P P + P++ PG Q + P P P +A VA +
Sbjct: 1997 PVSLNVPRPNQVSGPVMPSMPPGQWQQAPLPQQQPMPGLPRPVISMQAQAAVAGPRMPSV 2056
Query: 290 IPRRH---APLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNE-----LPSTLQRRTDFQ 341
P R + L+ L+R L +SP ++Q L + + + + +++RT
Sbjct: 2057 QPPRSISPSALQDLLR--------TLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKY 2108
Query: 342 VKGTVPEMEP-------PGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEP 394
V P M+P PG ++ + + + AG P PG PP P
Sbjct: 2109 VANQ-PGMQPQPGLQSQPGMQPQPGMHQQPSLQNLNAMQAGVPRPGVPPQQQAMGGLN-P 2166
Query: 395 SVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVP 454
PGH + E+ + QQQQQQQQQQQQQQQQQQ A +
Sbjct: 2167 QGQALNIMNPGHNPNMASMNPQYREMLRRQLLQQQQQQQQQQQQQQQQQQGSAGMAGGM- 2225
Query: 455 TMPPALQPFPAPVGPFDAAPA-----QVAVFLP---------PPHMQPPFVPAYPGLGYP 500
F P GP PA ++ LP M PGLG
Sbjct: 2226 ---AGHGQFQQPQGPGGYPPAMQQQQRMQQHLPLQGSSMGQMAAQMGQLGQMGQPGLGAD 2282
Query: 501 PMPRVPVV---GITPSQMVANAFCSAAQ---LQPQPATLLG--KAGAFPPPAIPSAPGSQ 552
P + I Q + S Q + PQ L G +A P I ++ +Q
Sbjct: 2283 STPNIQQALQQRILQQQQMKQQIGSPGQPNPMSPQQHMLSGQPQASHLPGQQIATSLSNQ 2342
Query: 553 AR-PRPNGAPWPPEPAP--APAPELDP 576
R P P +P P P +P+P + P
Sbjct: 2343 VRSPAPVQSPRPQSQPPHSSPSPRIQP 2369
Score = 39.7 bits (91), Expect = 0.008
Identities = 44/162 (27%), Positives = 59/162 (36%), Gaps = 18/162 (11%)
Query: 446 QAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLP---PPHMQPPFVPAYP--GLGYP 500
QA+ + P L P P P P+ P PP P P+ P G
Sbjct: 839 QASQLPCPPVTQSPLHPTPPPASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQT 898
Query: 501 PMPR---VPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRP 557
P P VP T S A + AQ+ PQP T + PP++ + SQ +P P
Sbjct: 899 PTPTPGSVPSATQTQSTPTVQA-AAQAQVTPQPQTPV------QPPSVATPQSSQQQPTP 951
Query: 558 NGAPWPPEPAPAPAPELD---PFEAQWAALEGKATVEKPSNP 596
A P P A +D P + A+ E + P P
Sbjct: 952 VHAQPPGTPLSQAAASIDNRVPTPSSVASAETNSQQPGPDVP 993
Score = 37.4 bits (85), Expect = 0.040
Identities = 44/182 (24%), Positives = 66/182 (36%), Gaps = 26/182 (14%)
Query: 425 KAQQQQQQQQQQQQQQQQQQQQAASVAPVP--TMPPALQPFPAPVGPFDAAPAQVAVFLP 482
K +QQQ Q + QQ Q +++ + VP ++P P AP G P+ P
Sbjct: 1849 KLRQQQIQHRLQQAQLMRRRMATMNTRNVPQQSLP---SPTSAPPGTPTQQPSTPQTPQP 1905
Query: 483 PPHMQPPFVPAYPGLGYPPMPRV-PVVGITPSQMVANAFCSAAQLQPQPATL-------- 533
P QP V P G+P + R P ++ + + QP PA +
Sbjct: 1906 PAQPQPSPVSMSPA-GFPSVARTQPPTTVSTGKPTSQVPAPPPPAQPPPAAVEAARQIER 1964
Query: 534 ----------LGKAGAFPPPAIP-SAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWA 582
+ + PP PGSQ P P P + + P + P + Q A
Sbjct: 1965 EAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNVPRPNQVSGPVMPSMPPGQWQQA 2024
Query: 583 AL 584
L
Sbjct: 2025 PL 2026
Score = 37.4 bits (85), Expect = 0.040
Identities = 54/247 (21%), Positives = 84/247 (34%), Gaps = 33/247 (13%)
Query: 233 PAEREAPDKKKAEAAAAPTVAPGPAQP--GHVSPTPATTSPGEKGEAGTPVAAGTTAAAI 290
P+ AP + + P PAQP VS +PA + + T V+ G + +
Sbjct: 1883 PSPTSAPPGTPTQQPSTPQTPQPPAQPQPSPVSMSPAGFPSVARTQPPTTVSTGKPTSQV 1942
Query: 291 PRRHAP-------------LEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNEL-PSTLQR 336
P P +E+ +Q ++ P + + +++ P +L
Sbjct: 1943 PAPPPPAQPPPAAVEAARQIEREAQQQQHLYRVNINNSMPPGRTGMGTPGSQMAPVSLNV 2002
Query: 337 RTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSV 396
QV G V PPG Q + P PG P A +
Sbjct: 2003 PRPNQVSGPVMPSMPPG------------QWQQAPLPQQQPMPGLPRPVISMQAQAAVAG 2050
Query: 397 PPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQ-----QQQQQQQQQQQQQQQAASVA 451
P + QP +PS + L + + QQQQQ + Q +Q+ A VA
Sbjct: 2051 PRMPSVQPPRSISPSALQDLLRTLKSPSSPQQQQQVLNILKSNPQLMAAFIKQRTAKYVA 2110
Query: 452 PVPTMPP 458
P M P
Sbjct: 2111 NQPGMQP 2117
Score = 36.6 bits (83), Expect = 0.069
Identities = 40/202 (19%), Positives = 74/202 (36%), Gaps = 27/202 (13%)
Query: 251 TVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFP 310
T PG P +PT +T G+ TP G+ +A + P Q Q
Sbjct: 872 TTPPGMTPPQPAAPTQPSTPVSSSGQTPTP-TPGSVPSATQTQSTPTVQAAAQAQ----- 925
Query: 311 ALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQI--S 368
Q +P + P ++ Q + T +PPG S + ++ ++
Sbjct: 926 VTPQPQTPVQ----------PPSVATPQSSQQQPTPVHAQPPGTPLSQAAASIDNRVPTP 975
Query: 369 SSFASAGA----PAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVA 424
SS ASA P P P T E + P PG + +E E++ +
Sbjct: 976 SSVASAETNSQQPGPDVPVLEMKTETQAEDTEP-----DPGESKGEPRSEMMEEDLQGAS 1030
Query: 425 KAQQQQQQQQQQQQQQQQQQQQ 446
+ +++ +Q+ + + +++
Sbjct: 1031 QVKEETDIAEQKSEPMEVDEKK 1052
Score = 35.4 bits (80), Expect = 0.15
Identities = 37/151 (24%), Positives = 50/151 (33%), Gaps = 19/151 (12%)
Query: 432 QQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFV 491
Q Q Q Q AA P+ + P P P V P H PP
Sbjct: 812 QPPAQTGVSQGQVPGAALPNPLNMLGPQASQLPCP-----------PVTQSPLHPTPP-- 858
Query: 492 PAYPGLGYPPMPRVPVVGITPSQMVA-----NAFCSAAQLQ-PQPATLLGKAGAFPPPAI 545
PA G P + G+TP Q A S+ Q P P ++ P +
Sbjct: 859 PASTAAGMPSLQHTTPPGMTPPQPAAPTQPSTPVSSSGQTPTPTPGSVPSATQTQSTPTV 918
Query: 546 PSAPGSQARPRPNGAPWPPEPAPAPAPELDP 576
+A +Q P+P PP A + + P
Sbjct: 919 QAAAQAQVTPQPQTPVQPPSVATPQSSQQQP 949
Score = 29.6 bits (65), Expect = 8.4
Identities = 41/200 (20%), Positives = 70/200 (35%), Gaps = 21/200 (10%)
Query: 418 EEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQV 477
E++ ++ K +++++ + +Q Q + P + P QP P GP ++
Sbjct: 656 EKIYKIQKELEEKRRSRLHKQGILGNQPALPAPGAQPPVIPQAQPVRPPNGPLSLPVNRM 715
Query: 478 AV------FLPPP--HMQPPFVPAYPGLGYP--------PMPRVPVVGITPSQMVANAFC 521
V F P ++Q P P P P M VP + I+PS+M
Sbjct: 716 QVSQGMNSFNPMSLGNVQLPQAPMGPRAASPMNHSVQMNSMGSVPGMAISPSRMPQPPNM 775
Query: 522 SAAQLQPQPATLLGKAGAFPPPAIPSAPGSQA-----RPRPNGAPWPPEPAPAPAPELDP 576
A A ++ P PS+ G+ + P G P A L+
Sbjct: 776 MGAHTNNMMAQAPAQSQFLPQNQFPSSSGAMSVGMGQPPAQTGVSQGQVPGAALPNPLNM 835
Query: 577 FEAQWAALEGKATVEKPSNP 596
Q + L + P +P
Sbjct: 836 LGPQASQLPCPPVTQSPLHP 855
>gi|163965366 nascent polypeptide-associated complex alpha subunit
isoform a [Homo sapiens]
Length = 2078
Score = 65.5 bits (158), Expect = 1e-10
Identities = 97/366 (26%), Positives = 118/366 (32%), Gaps = 71/366 (19%)
Query: 225 FRLSGGGRPAEREAP-------DKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEA 277
F G PA ++AP KKA A AP P P PA T P KG
Sbjct: 895 FPKEGPATPAPKQAPALSMTSSSPKKARATPAPKGIPASPSPKGAPTPPAATPPSPKGGP 954
Query: 278 GTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPAL-SQKNSPFKRQLSLRLNELPSTLQR 336
TP + AP S +G PA S K +P T
Sbjct: 955 ATP----------SPKWAPTPPAATPPSPKGGPATPSPKGAP--------------TPPA 990
Query: 337 RTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAP---GPPPATTGTSAWGE 393
T KG P GA ++ T S + A P P PPA T S G
Sbjct: 991 ATPPSPKGGPATPSPKGAPTPPAV----TPPSPKGSPAATPFPKGASTPPAATPPSPKGS 1046
Query: 394 PSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPV 453
P+ P G TP+ A + + A+ P
Sbjct: 1047 PAATP---LPKGAPTTPA--------------ATLPSPKGGPATPSLKGAPTPPAATPPS 1089
Query: 454 PTMPPAL-QPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITP 512
P PA P AP+ P P+ PPH P PA PP P+ + P
Sbjct: 1090 PKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA----ATPPSPKGGLATPPP 1145
Query: 513 SQMVANAFCSAAQLQPQP----ATLLGKAGAFPPPAIPSAP-GSQARPRPNGAPWPPEPA 567
A + A P P AT K P A P +P G A P P GAP P
Sbjct: 1146 K----GAPTTPAATPPSPKGGLATPPPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAAT 1201
Query: 568 PAPAPE 573
P P+P+
Sbjct: 1202 P-PSPK 1206
Score = 57.4 bits (137), Expect = 4e-08
Identities = 96/369 (26%), Positives = 114/369 (30%), Gaps = 65/369 (17%)
Query: 231 GRPAEREAPDKKKAEAAAAPTVAPG-PAQ---PGHVSPTPATTSPGEKGEAGTPVAAGTT 286
G PA P AA P G PA P TPA T P KG TP G
Sbjct: 1021 GSPAATPFPKGASTPPAATPPSPKGSPAATPLPKGAPTTPAATLPSPKGGPATPSLKG-- 1078
Query: 287 AAAIPRRHAPLEQLVRQGSFRGFPAL-SQKNSPF---------KRQLSLRLNELPSTLQR 336
AP S +G PA S K +P K L+ ++ T
Sbjct: 1079 --------APTPPAATPPSPKGGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPA 1130
Query: 337 RTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPP--PATTGTSAWGEP 394
T KG + P GA + + T S A P G P PA T S G
Sbjct: 1131 ATPPSPKGGLATPPPKGAPTTPA----ATPPSPKGGLATPPPKGAPTTPAATPPSPKGGL 1186
Query: 395 SVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVP 454
+ P TP + L S + + A P
Sbjct: 1187 ATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGGLATPSPKGAPTTPAA 1246
Query: 455 TMP-----PALQPFP-APVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVV 508
T P PA P AP P P+ PPH P P + PP P+
Sbjct: 1247 TPPSPKGGPATPPPKGAPTPPAATPPSLKGGLATPPHKGAP----NPAVVTPPSPK---- 1298
Query: 509 GITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAP-GSQARPRPNGAPWPPEPA 567
PAT K PP A P +P GS P P GAP PP
Sbjct: 1299 -------------------GGPATSPPKGAPTPPAATPPSPKGSPGTPPPKGAPTPPAVT 1339
Query: 568 PAPAPELDP 576
P P+P+ P
Sbjct: 1340 P-PSPKGTP 1347
Score = 57.4 bits (137), Expect = 4e-08
Identities = 90/377 (23%), Positives = 121/377 (32%), Gaps = 62/377 (16%)
Query: 229 GGGRPAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAA 288
G PA P K A + P AP P PA T P KG GTP
Sbjct: 1285 GAPNPAVVTPPSPKGGPATSPPKGAPTP---------PAATPPSPKGSPGTP-------- 1327
Query: 289 AIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPE 348
P + AP V S +G P L K + ++ T T G P
Sbjct: 1328 --PPKGAPTPPAVTPPSPKGTPTLPATTPSSKGGPTTPSSKEGPTPPAATPSHKGG--PA 1383
Query: 349 MEPPG----------AGDSDS--------INALCTQISSSFASAGAPAPGPPPATTGTSA 390
M PP GD S A T ++ A+ + PPA T S
Sbjct: 1384 MTPPSPKRGPAIPSPKGDPTSPAVIPLSPKKAPATPVTREGAATPSKGDLTPPAVTPVSL 1443
Query: 391 WGEP--SVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAA 448
P S P P K P+ + V ++ +Q ++ A
Sbjct: 1444 KKAPATSAPKGGPATPSSKGDPT--------LPAVTPPSPKEPPAPKQVATSSSPKKAPA 1495
Query: 449 SVAPV--PTMPPAL--QPFPAPVGPFD-----AAPAQVAVFLPPPHMQPPFVPAYPGLGY 499
+ AP+ PT+P + P P P A A + P + P P +
Sbjct: 1496 TPAPMGAPTLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALIPPAMTV 1555
Query: 500 PPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNG 559
P + P + P+ A A S+ + PA P P P + P P
Sbjct: 1556 PSPKKTPAI---PTPKEAPATPSSKEASSPPAVTPSTYKGAPSPKELLIPPAVTSPSPKE 1612
Query: 560 APWPPEPAPAPAPELDP 576
AP PP P P+PE P
Sbjct: 1613 APTPPAVTP-PSPEKGP 1628
Score = 55.8 bits (133), Expect = 1e-07
Identities = 99/382 (25%), Positives = 118/382 (30%), Gaps = 51/382 (13%)
Query: 231 GRPAEREAPDKKKAEAAAAPTVAPGPAQPGH--VSPTPATTSPGEKGEAGTPVAAG--TT 286
G PA AA P+ G A P H TPA T P KG TP G TT
Sbjct: 1092 GGPATPSPKGAPMPPAATPPSPKGGLATPPHKGAPTTPAATPPSPKGGLATPPPKGAPTT 1151
Query: 287 AAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPF-KRQLSLRLNELPSTLQRRTDFQVKGT 345
AA P +P L +G P P K L+ + T T KG
Sbjct: 1152 PAATPP--SPKGGLATPPP-KGAPTTPAATPPSPKGGLATPSPKGAPTTPAATPPSPKGG 1208
Query: 346 VPEMEPPGAGDSDSINALCTQISSSFASAGAPAP-GPP--PATTGTSAWGEPSVPPAAAF 402
+ P GA + + S P+P G P PA T S G P+ PP
Sbjct: 1209 LATPSPKGAPTTPAATP-----PSPKGGLATPSPKGAPTTPAATPPSPKGGPATPPPKGA 1263
Query: 403 QPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQP 462
TP + L + P PP+ +
Sbjct: 1264 PTPPAATPPSLKGGLAT------------------------PPHKGAPNPAVVTPPSPKG 1299
Query: 463 FPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCS 522
PA P A A PP P P G PP P TP+
Sbjct: 1300 GPATSPPKGAPTPPAAT--PPSPKGSPGTPPPKGAPTPPAVTPPSPKGTPTLPATTPSSK 1357
Query: 523 AAQLQPQPATLLGKAGAFPPPAIPSAPGSQAR--PRPNGAPWPPEPAPAP-APELDPFEA 579
P T K G PP A PS G A P P P P P P +P + P
Sbjct: 1358 GG-----PTTPSSKEGPTPPAATPSHKGGPAMTPPSPKRGPAIPSPKGDPTSPAVIPLSP 1412
Query: 580 QWAALEGKATVEKPSNPFSGDL 601
+ A T E + P GDL
Sbjct: 1413 KKAPAT-PVTREGAATPSKGDL 1433
Score = 47.0 bits (110), Expect = 5e-05
Identities = 86/348 (24%), Positives = 121/348 (34%), Gaps = 50/348 (14%)
Query: 250 PTVAPGP---AQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSF 306
PTVA P A P V+PT A + A +P GT + A P+ H V++G+
Sbjct: 643 PTVAAFPLESADPAGVAPTTAKGTSTYTTTA-SPFLEGTVSLA-PKNHP-----VKEGTL 695
Query: 307 RGFPALSQKN-----SPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSIN 361
P + + +P + L L + P PPG D I+
Sbjct: 696 TTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPPAGTPPGTKKVDGIS 755
Query: 362 ---ALCTQISS--------SFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTP 410
AL SS S ASA A + G T T PS P + P KR P
Sbjct: 756 HTSALAPVASSPKECPTEDSGASATASSKG-----TLTYLADSPS-PLGVSVSPQTKRPP 809
Query: 411 SEA-----ERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPA 465
++ + + +S + + Q + A + +P P P P P+
Sbjct: 810 TKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTHSPTPPSPKGA-PTPS 868
Query: 466 PVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPM-PRVPVVGITPSQMVANAFCSAA 524
V P V LPP P V P +P P P P+ + ++ A
Sbjct: 869 AVTPLSPK----GVTLPPKETPTPSVVNLP---FPKEGPATPAPKQAPALSMTSSSPKKA 921
Query: 525 QLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAP 572
+ P P + A P P P + P P G P P P AP P
Sbjct: 922 RATPAPKGI----PASPSPKGAPTPPAATPPSPKGGPATPSPKWAPTP 965
Score = 39.7 bits (91), Expect = 0.008
Identities = 91/433 (21%), Positives = 140/433 (32%), Gaps = 81/433 (18%)
Query: 204 KECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPDKKKAEAAAAPTVAPGPAQPGHVS 263
K+ T+A + + +G L P+ +E P K+ +++P AP P
Sbjct: 1444 KKAPATSAPKGGPATPSSKGDPTLPAVTPPSPKEPPAPKQVATSSSPKKAPATPAPMGAP 1503
Query: 264 PTPATTSPGEKGEAGTPVA--------AGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQK 315
PA K TP + A + P AP E L+ P
Sbjct: 1504 TLPAVIPSSPKEVPATPSSRRDPIAPTATLLSKKTPATLAPKEALI--------PPAMTV 1555
Query: 316 NSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAG 375
SP K E P+T P + ++ S A+ + G
Sbjct: 1556 PSPKKTPAIPTPKEAPAT------------------PSSKEASSPPAV-----TPSTYKG 1592
Query: 376 APAPGP---PPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQ 432
AP+P PPA T S P+ PPA TP E+ + K
Sbjct: 1593 APSPKELLIPPAVTSPSPKEAPT-PPAV--------TPPSPEK--GPATPAPKGTPTSPP 1641
Query: 433 QQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGP-------FDAAPAQVAVFLPPPH 485
+ + + T+P A + PA GP AP + P
Sbjct: 1642 VTPSSLKDSPTSPASVTCKMGATVPQASKGLPAKKGPTALKEVLVAPAPESTPIITAPTR 1701
Query: 486 MQP-------PFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAG 538
P P P + P+ + P+ ++ S+ + + A+ K
Sbjct: 1702 KGPQTKKSSATSPPICPDPSAKNGSKGPLSTVAPAPLLPVQKDSSKTAKGKDASHSPKGP 1761
Query: 539 AFPPPAIPSAPGSQAR-----PRP-----NGAPWPPEP---APAPAPELDPFEAQWAALE 585
PP + S P + A P+P + AP PP AP+P P L P + Q+
Sbjct: 1762 LAPPESKASTPLTAAAFEKVLPKPESASVSAAPSPPVSLPLAPSPVPTLPP-KQQFLPSS 1820
Query: 586 GKATVEKPSNPFS 598
+E PS P +
Sbjct: 1821 PGLVLESPSKPLA 1833
Score = 33.5 bits (75), Expect = 0.58
Identities = 70/317 (22%), Positives = 100/317 (31%), Gaps = 42/317 (13%)
Query: 266 PATTSPGEKGEAGTP-VAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPF-KRQL 323
P + P K TP VAA +A P AP + +G + SPF + +
Sbjct: 629 PDSAGPLLKSSLITPTVAAFPLESADPAGVAPT-------TAKGTSTYTTTASPFLEGTV 681
Query: 324 SLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPP 383
SL P T + T E P ++ L T + + P+P PP
Sbjct: 682 SLAPKNHPVKEGTLTTLPLVPTASENCPVAPSPQNTCAPLATLVLAPEIPKSVPSPSLPP 741
Query: 384 ATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQ 443
A T + +A P +P E ++ + A +
Sbjct: 742 AGTPPGTKKVDGISHTSALAPVAS-SPKECP------TEDSGASATASSKGTLTYLADSP 794
Query: 444 QQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQV----AVFLPPPHMQPPFVPAYPGLGY 499
SV+P PP + P P + V A FLP + P +
Sbjct: 795 SPLGVSVSPQTKRPPTKKGSAGPDTPIGNLSSPVSPVEASFLPENSLSFQGSKDSPATTH 854
Query: 500 PPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNG 559
P P P TPS + L P+ TL PP P+ P
Sbjct: 855 SPTPPSPKGAPTPS--------AVTPLSPKGVTL-------PPKETPT-------PSVVN 892
Query: 560 APWPPEPAPAPAPELDP 576
P+P E PAP+ P
Sbjct: 893 LPFPKEGPATPAPKQAP 909
>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
sapiens]
Length = 816
Score = 64.7 bits (156), Expect = 2e-10
Identities = 95/355 (26%), Positives = 118/355 (33%), Gaps = 40/355 (11%)
Query: 237 EAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRR--H 294
EAP K+ A +A A GP PG SP A S E G P A + P
Sbjct: 140 EAP-KRSALSAGARRDTSGPT-PGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPR 197
Query: 295 APLEQLVRQGSFRGFPALSQKNS-------PFKRQLSLRLNELPSTLQRRTDFQVKGTVP 347
+ + PA ++ S P R LS L S R+ +GT
Sbjct: 198 KSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPA--RSGPSARGTPR 255
Query: 348 EMEPPGAGDSDSINALCTQISSSFASAGAPAPGP----PPATTGTSAWGEPSVPPAAAFQ 403
P + AL + APA GP P AT SA PS PP+
Sbjct: 256 APAHPSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315
Query: 404 PGHKRTP-SEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPV--PTMPPAL 460
P TP S+A L + A Q A ++ P+ P PPA
Sbjct: 316 PSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPAS 375
Query: 461 QPFPAPVGPFDAAPAQVAV-FLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANA 519
P P AP +AV L P PP P P P V PSQ
Sbjct: 376 PPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQA---- 431
Query: 520 FCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPEL 574
P +L A PP +P +P + P+ P P P P AP L
Sbjct: 432 ----------PPSL-----AAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPL 471
Score = 64.3 bits (155), Expect = 3e-10
Identities = 105/428 (24%), Positives = 144/428 (33%), Gaps = 67/428 (15%)
Query: 193 AACLERKQRREKECGVTAAFDASRTSFAREGSFRLSGGGRPAEREAPDKKKAEAAAAPTV 252
A + RK E+ G+ A S R G R S R + A A
Sbjct: 50 AGAVGRKPLAERAGGIGGA--TIPESAPRAGPTRTS-------RPPASGRGERAPPAKNT 100
Query: 253 APGP-AQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGF-- 309
+PGP + PG S TT PG G+ G ++A T A AP + G+ R
Sbjct: 101 SPGPVSSPGRAS---GTTRPGPLGQKGLRISAEETVARGKATEAPKRSALSAGARRDTSG 157
Query: 310 -------PALSQKNSPFKRQLSL-----RLNELPSTLQRRTDFQVKGTVPEMEPPGAGDS 357
PA+++++ ++ L P T R EP A
Sbjct: 158 PTPGTPSPAMARRSRAAGTEVGLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARR 217
Query: 358 DSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWL 417
Q +S + + + P PA +G SA G P P H P
Sbjct: 218 RPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAP-------AHPSQPKPKGLQA 270
Query: 418 EEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQV 477
QV ++ + S P P+ PP+LQ P+P P+Q
Sbjct: 271 LRPPQVTPPRKDAAPALGPLSSSPLATP-SPSAPPSPSAPPSLQTLPSPPA---TPPSQA 326
Query: 478 AV------------FLPPPHMQPPFVP---AYPGLGYPPM------PRVPVVG--ITPSQ 514
FLP P + P P A P L PP+ P P + TPS
Sbjct: 327 TTSLGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSP 386
Query: 515 MVANAFCS---AAQLQPQPATLLGKAGAFP--PPAIPSA-PGSQARPRPNGAPWPPEPAP 568
NA A P P+ + + P PP PSA P SQA P P P+P
Sbjct: 387 QAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSP 446
Query: 569 APAPELDP 576
+P + P
Sbjct: 447 PASPPMSP 454
Score = 55.1 bits (131), Expect = 2e-07
Identities = 88/386 (22%), Positives = 119/386 (30%), Gaps = 49/386 (12%)
Query: 208 VTAAFDASRTSFAREGSFRLSGGG---RPAEREAPDKK---KAEAAAAPTVAPGPAQPGH 261
V++A + S T + R S GG RPA R + A + P+ P P H
Sbjct: 200 VSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSARGTPRAPAH 259
Query: 262 VSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKR 321
S + TP A P +PL A ++P
Sbjct: 260 PSQPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPL-------------ATPSPSAPPSP 306
Query: 322 QLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASA------G 375
L LPS P PP + S+ + Q + SF +
Sbjct: 307 SAPPSLQTLPS--------------PPATPPSQATT-SLGSPTLQATHSFLPSPPLSPLA 351
Query: 376 APAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQ 435
P P PPA PS P + P +P + Q A Q
Sbjct: 352 TPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQ-APFSPPPSPPVQ 410
Query: 436 QQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFD-AAPAQVAVFLPPPHMQPPFVPAY 494
+ S P PP+L P V P A+P PPP PP
Sbjct: 411 APFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPP 470
Query: 495 PGLGYPPMPRVPVVGITPSQMVAN---AFCSAAQLQPQPATLLGKAGAFPPPAIP--SAP 549
L PP P + P Q + + +F A P + + PP A P +AP
Sbjct: 471 LQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAP 530
Query: 550 GSQARPRPNGAP--WPPEPAPAPAPE 573
Q P P +P P P P P+
Sbjct: 531 LLQVPPSPPASPTLQAPRRPPTPGPD 556
Score = 50.4 bits (119), Expect = 5e-06
Identities = 107/410 (26%), Positives = 138/410 (33%), Gaps = 64/410 (15%)
Query: 240 DKKKAEAAAAPTVA--PG---PAQPGHVSPTPATTSPGEK--GEAGT----PVA---AGT 285
DK KA AAA A PG P PG P P T + G AG P+A G
Sbjct: 6 DKAKAGAAARTPAARAPGLLTPRPPGSPRPPPPVTPAALRVLGAAGAVGRKPLAERAGGI 65
Query: 286 TAAAIPR---RHAPLEQLVRQGSFRGFPALSQKN-------SPFKRQLSLRLNELPSTLQ 335
A IP R P S RG A KN SP + + R L Q
Sbjct: 66 GGATIPESAPRAGPTRTSRPPASGRGERAPPAKNTSPGPVSSPGRASGTTRPGPLG---Q 122
Query: 336 RRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPP-PA------TTGT 388
+ + TV + A +++A + +S P PG P PA GT
Sbjct: 123 KGLRISAEETVARGKATEAPKRSALSAGARRDTSG------PTPGTPSPAMARRSRAAGT 176
Query: 389 SAWGEPSVPPAAAFQPG----HKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQ 444
G P P+A +P K S +E E S A+ + Q+ +
Sbjct: 177 EV-GLPRPAPSARPRPPTEGPRKSVSSASEHSTTEPSPAARRRPSAGGGLQRPASRSLSS 235
Query: 445 QQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPR 504
+P + P A AP P P + L PP + PP A P LG P+
Sbjct: 236 SATPLSSPARSGPSARGTPRAPAHPSQPKPKGLQA-LRPPQVTPPRKDAAPALG--PLSS 292
Query: 505 VPVVGITPSQMVANAFCSAAQLQPQPA--------------TLLGKAGAFP-PPAIPSA- 548
P+ +PS + + + Q P P TL P PP P A
Sbjct: 293 SPLATPSPSAPPSPSAPPSLQTLPSPPATPPSQATTSLGSPTLQATHSFLPSPPLSPLAT 352
Query: 549 PGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEKPSNPFS 598
P QA P P P+P +P L P V PFS
Sbjct: 353 PPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFS 402
Score = 38.5 bits (88), Expect = 0.018
Identities = 85/352 (24%), Positives = 115/352 (32%), Gaps = 54/352 (15%)
Query: 232 RPAEREAPDKKKAEA----AAAPTVAPGPAQPGHVSPTPAT-TSPGEKGEAGTPVAAGTT 286
RP + P K A A +++P P P+ P S P+ T P TP + TT
Sbjct: 272 RPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTLPSPPA---TPPSQATT 328
Query: 287 AAAIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTV 346
+ P A SF P LS +P + P L
Sbjct: 329 SLGSPTLQAT-------HSFLPSPPLSPLATPPP--------QAPPAL---------ALP 364
Query: 347 PEMEPPGAGDSDSINALCT---QISSSFASAGAPAP-GPPPATTGTSAWGEPSVPPAA-A 401
P PP S ++ L T Q ++ A AP PPP+ + + P+ PP + +
Sbjct: 365 PLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPS 424
Query: 402 FQPGHKRTPSEAERWLE-EVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPAL 460
P + PS A L+ S A Q P P PPAL
Sbjct: 425 ATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKPPPQAPPAL 484
Query: 461 QPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAF 520
P A P+ A F P L PP PV+ Q+ +
Sbjct: 485 A-----TPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPS-- 537
Query: 521 CSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAP 572
PA+ +A PP P S R AP PP P P+ +P
Sbjct: 538 --------PPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPP-PPPSRSP 580
Score = 30.8 bits (68), Expect = 3.8
Identities = 45/188 (23%), Positives = 65/188 (34%), Gaps = 26/188 (13%)
Query: 239 PDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLE 298
P + + AAP + P+ P +P+ T P + A P+AA A P AP
Sbjct: 427 PPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQ---APPPLAAPPLQLAKPPPQAPPA 483
Query: 299 QLVRQ-GSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTD------FQVKGTVPEM-- 349
+ PA +PF SL ++ L + + QV + P
Sbjct: 484 LATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAAPLLQVPPSPPASPT 543
Query: 350 -----EPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQP 404
PP G S++ A AP P PPP+ + +S S P A
Sbjct: 544 LQAPRRPPTPGPDTSVSG------PRLTLALAPGPPPPPSRSPSSTL---SGPDLAGHSS 594
Query: 405 GHKRTPSE 412
TP E
Sbjct: 595 SATSTPEE 602
>gi|78042577 MAP7 domain containing 1 [Homo sapiens]
Length = 841
Score = 63.5 bits (153), Expect = 5e-10
Identities = 69/271 (25%), Positives = 106/271 (39%), Gaps = 36/271 (13%)
Query: 239 PDKKKAEAAAAPTVAPGPAQPGHVSPTPATTS------PGEKGEAGTPVAAGTTAAAIPR 292
P + +AA V P A ++P T S GE+GE P A G+ A R
Sbjct: 347 PQPDRTHPSAAVPVCPRSASASPLTPCSVTRSVHRCAPAGERGERRKPNAGGSPAPVRRR 406
Query: 293 RHA-PLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNE-LPSTLQRRTDFQVKGTVPEME 350
A P+++ ++ R ++ S R+ SL+ + LP++ + R T E+
Sbjct: 407 PEASPVQKKEKKDKER---ENEKEKSALARERSLKKRQSLPASPRARLS---ASTASELS 460
Query: 351 PPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTP 410
P S S+S+ +P P P P T +PP G +P
Sbjct: 461 PKSKARPSSP-------STSWHRPASPCPSPGPGHT---------LPPKPPSPRGTTASP 504
Query: 411 SEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVG-- 468
R EE + A + + Q +++ +++ AA +P P+ PA P PAP
Sbjct: 505 KGRVRRKEEAKESPSAAGPEDKSQSKRRASNEKES-AAPASPAPS--PAPSPTPAPPQKE 561
Query: 469 -PFDAAPAQVAVFLPPPHMQPPFVPAYPGLG 498
P P AV PP PP P+ P G
Sbjct: 562 QPPAETPTDAAVLTSPPAPAPPVTPSKPMAG 592
Score = 37.4 bits (85), Expect = 0.040
Identities = 34/103 (33%), Positives = 44/103 (42%), Gaps = 12/103 (11%)
Query: 472 AAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQM---VANAFCSAAQLQP 528
A PA VA P P P P+ P P P +V TP + NA S+ QL
Sbjct: 13 APPAVVARTPPEPRPSPEGDPSPP-----PPPMSALVPDTPPDTPPAMKNA-TSSKQLPL 66
Query: 529 QPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPA 571
+P + G+ G P P +P S+A+ R P PP P A
Sbjct: 67 EPESPSGQVGPRPAPPQEESPSSEAKSR---GPTPPAMGPRDA 106
Score = 32.3 bits (72), Expect = 1.3
Identities = 21/64 (32%), Positives = 27/64 (42%), Gaps = 7/64 (10%)
Query: 538 GAFPPPAIPSAPGSQARPRPNGAPWPPEP-----APAPAPELDPFEAQWAALEGKATVEK 592
GA PPA+ + + RP P G P PP P P P+ P A A K +
Sbjct: 10 GAGAPPAVVARTPPEPRPSPEGDPSPPPPPMSALVPDTPPDTPP--AMKNATSSKQLPLE 67
Query: 593 PSNP 596
P +P
Sbjct: 68 PESP 71
Score = 31.2 bits (69), Expect = 2.9
Identities = 26/107 (24%), Positives = 41/107 (38%), Gaps = 7/107 (6%)
Query: 375 GAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQ 434
G P+P PPP + P PPA K+ P E E +V + Q++
Sbjct: 31 GDPSPPPPPMSALVPDT-PPDTPPAMKNATSSKQLPLEPESPSGQVG----PRPAPPQEE 85
Query: 435 QQQQQQQQQQQQAASVAPVPTMPP--ALQPFPAPVGPFDAAPAQVAV 479
+ + + ++ P PP + QP P V D+ P + V
Sbjct: 86 SPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAVPASDSPPTKQEV 132
Score = 29.6 bits (65), Expect = 8.4
Identities = 22/73 (30%), Positives = 33/73 (45%), Gaps = 10/73 (13%)
Query: 1 MSRSAAASGGPRRPER--------HLPPAPCGAPGPPETCRTEPDG-AGTMNKLRQSLRR 51
+S S A+ P+ R H P +PC +PGP T +P GT + +RR
Sbjct: 451 LSASTASELSPKSKARPSSPSTSWHRPASPCPSPGPGHTLPPKPPSPRGTTASPKGRVRR 510
Query: 52 RKPA-YVPEASRP 63
++ A P A+ P
Sbjct: 511 KEEAKESPSAAGP 523
>gi|90903231 huntingtin [Homo sapiens]
Length = 3144
Score = 63.2 bits (152), Expect = 7e-10
Identities = 38/83 (45%), Positives = 42/83 (50%), Gaps = 8/83 (9%)
Query: 414 ERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAA 473
E+ ++ + QQQQQQQQQQQQQQQQQQQQ P P PP Q P P
Sbjct: 5 EKLMKAFESLKSFQQQQQQQQQQQQQQQQQQQQQQQPPPPPPPPPPPQ-LPQP------- 56
Query: 474 PAQVAVFLPPPHMQPPFVPAYPG 496
P Q LP P PP P PG
Sbjct: 57 PPQAQPLLPQPQPPPPPPPPPPG 79
Score = 34.3 bits (77), Expect = 0.34
Identities = 20/64 (31%), Positives = 25/64 (39%), Gaps = 8/64 (12%)
Query: 541 PPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEGKATVEKPSNPFSGD 600
PPP P P +P P P P+P P P P P G A E+P + +
Sbjct: 42 PPPPPPPPPPQLPQPPPQAQPLLPQPQPPPPPPPPP--------PGPAVAEEPLHRPKKE 93
Query: 601 LQKT 604
L T
Sbjct: 94 LSAT 97
>gi|160707881 formin 2 [Homo sapiens]
Length = 1722
Score = 61.6 bits (148), Expect = 2e-09
Identities = 63/222 (28%), Positives = 81/222 (36%), Gaps = 35/222 (15%)
Query: 363 LCTQISSSFASAGAPAPGPPPATTGTSAWGEP-SVPP---AAAFQPGHKRTPSEAERWLE 418
+ Q+ S + P PPP+ ++ G+P S PP + FQ H+ + S A +
Sbjct: 794 ISVQLDSHQPTQSISQPPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSC 853
Query: 419 EVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVA 478
+ + + VP PP L P P A P
Sbjct: 854 NIPSPPPLPCTESSSSMP------------GLGMVPPPPPPLPGMTVPTLPSTAIPQ--- 898
Query: 479 VFLPPP----HMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLL 534
PPP M PP P PG G PP P +P GI P + A P P L
Sbjct: 899 ---PPPLQGTEMLPPPPPPLPGAGIPPPPPLPGAGILPLPPLPGAGI------PPPPPLP 949
Query: 535 GKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDP 576
G A PPP +P A P P GA PP P P P + P
Sbjct: 950 G-AAIPPPPPLPGAGIPLPPPLP-GAGIPPPP-PLPGAGIPP 988
Score = 59.3 bits (142), Expect = 1e-08
Identities = 65/221 (29%), Positives = 81/221 (36%), Gaps = 30/221 (13%)
Query: 365 TQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHK------------RTPSE 412
T+ + F G PGP A G E V AA Q G + + +E
Sbjct: 133 TECADPFEVTGPGGPGPAEARVGGRPIAE-DVETAAGAQDGQRTSSGSDTDIYSFHSATE 191
Query: 413 AERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDA 472
E L ++ Q + QQQQQQQ Q Q QQQQQQQQ P A+ P P D
Sbjct: 192 QEDLLSDIQQAIRLQQQQQQQLQLQLQQQQQQQQLQGAEEPAAPPTAVSPQPGAFLGLDR 251
Query: 473 APAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPAT 532
FL P P P + + P + A Q P P
Sbjct: 252 -------FLLGPSGGAGEAPGSP----DTEQALSALSDLPESLAAEP--REPQQPPSPGG 298
Query: 533 L-LGKAGAFP--PPAIPSAPGSQARPRPNGAPWPPEPAPAP 570
L + +A + P PA +P S A P P P E A AP
Sbjct: 299 LPVSEAPSLPAAQPAAKDSPSSTAFPFPEAGP-GEEAAGAP 338
Score = 59.3 bits (142), Expect = 1e-08
Identities = 67/224 (29%), Positives = 80/224 (35%), Gaps = 41/224 (18%)
Query: 364 CTQISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQV 423
CT+ SSS G P PPP T P++P A QP P + L
Sbjct: 863 CTESSSSMPGLGMVPPPPPPLPGMTV----PTLPSTAIPQP----PPLQGTEMLPPPPPP 914
Query: 424 AKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQ-----VA 478
A + P+P +P A P P P+ P A P
Sbjct: 915 LPGAGIPPPPPLP----------GAGILPLPPLPGAGIPPPPPL-PGAAIPPPPPLPGAG 963
Query: 479 VFLPPP----HMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPATLL 534
+ LPPP + PP P PG G PP P +P GI P + A P P L
Sbjct: 964 IPLPPPLPGAGIPPP--PPLPGAGIPPPPPLPGAGIPPPPPLPGAGI------PPPPPLP 1015
Query: 535 GKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPA----PAPEL 574
G AG PPP +P A P P PP P P P P L
Sbjct: 1016 G-AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPL 1058
Score = 56.2 bits (134), Expect = 8e-08
Identities = 48/136 (35%), Positives = 55/136 (40%), Gaps = 18/136 (13%)
Query: 448 ASVAPVPTMPPALQPFPAPV--GPFDAAPAQVAVFLPPPHMQP----PFVPAYPGLGYPP 501
A + P P +P A P P P+ P +PPP P P P PG G PP
Sbjct: 1039 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1098
Query: 502 MPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSA--PGSQARPRPNG 559
P +P VGI P + A P P L G AG PPP +P A P PR
Sbjct: 1099 PPPLPGVGIPPPPPLPGAGI------PPPPPLPG-AGIPPPPPLPGAGIPPPPPLPRVGI 1151
Query: 560 APWPPEPA---PAPAP 572
P PP P P P P
Sbjct: 1152 PPPPPLPGAGIPPPPP 1167
Score = 54.7 bits (130), Expect = 2e-07
Identities = 47/138 (34%), Positives = 54/138 (39%), Gaps = 20/138 (14%)
Query: 448 ASVAPVPTMPPALQPFPAPV--GPFDAAPAQVAVFLPPPHMQP----PFVPAYPGLGYPP 501
A + P P +P A P P P+ P +PPP P P P PG G PP
Sbjct: 995 AGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGAGIPP 1054
Query: 502 MPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPN-GA 560
P +P GI P + A P P L G AG PPP +P A P P G
Sbjct: 1055 PPPLPGAGIPPPPPLPGAGI------PPPPPLPG-AGIPPPPPLPGAGIPPPPPLPGVGI 1107
Query: 561 PWPPE------PAPAPAP 572
P PP P P P P
Sbjct: 1108 PPPPPLPGAGIPPPPPLP 1125
Score = 52.4 bits (124), Expect = 1e-06
Identities = 49/140 (35%), Positives = 54/140 (38%), Gaps = 30/140 (21%)
Query: 448 ASVAPVPTMPPALQPFPAP---VGPFDAAPAQVAVFLPPPHMQP---PFVPAYPGLGYPP 501
A + P P +P A P P P VG P A PPP + P P PG+G PP
Sbjct: 1127 AGIPPPPPLPGAGIPPPPPLPRVGIPPPPPLPGAGIPPPPPLPGAGIPPPPPLPGVGIPP 1186
Query: 502 MPRVPVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPP-----AIPSAPGSQARPR 556
P +P VGI P P P L AG PPP IP AP P
Sbjct: 1187 PPPLPGVGIPP---------------PPP---LPGAGIPPPPPLPGMGIPPAPAPPLPPP 1228
Query: 557 PNGAPWPPEPAPAPAPELDP 576
G P PP P P L P
Sbjct: 1229 GTGIP-PPPLLPVSGPPLLP 1247
Score = 49.3 bits (116), Expect = 1e-05
Identities = 55/217 (25%), Positives = 74/217 (34%), Gaps = 40/217 (18%)
Query: 385 TTGTSAWGEPSVPPAAAFQPGHKRTPSEAE-----RWLEEVSQVAKAQQQQQQQQQQQQQ 439
T+ T G ++PP PG P AE ++ E+S + ++ Q Q
Sbjct: 746 TSPTEEGGVLTLPPVDGL-PGRPPCPPGAESGPQTKFCSEISLIVSPRRISVQLDSHQPT 804
Query: 440 QQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQ------------ 487
Q Q P PP+L P P ++ H
Sbjct: 805 QSISQ---------PPPPPSLLWSAGQGQPGSQPPHSISTEFQTSHEHSVSSAFKNSCNI 855
Query: 488 --PPFVP------AYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQ-----PQPATLL 534
PP +P + PGLG P P P+ G+T + + A LQ P P L
Sbjct: 856 PSPPPLPCTESSSSMPGLGMVPPPPPPLPGMTVPTLPSTAIPQPPPLQGTEMLPPPPPPL 915
Query: 535 GKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPA 571
AG PPP +P A P P PP P P A
Sbjct: 916 PGAGIPPPPPLPGAGILPLPPLPGAGIPPPPPLPGAA 952
Score = 30.8 bits (68), Expect = 3.8
Identities = 25/79 (31%), Positives = 32/79 (40%), Gaps = 9/79 (11%)
Query: 450 VAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRV---- 505
+ P P +P A P P P+ PA A LPPP P P P G P +P+V
Sbjct: 1195 IPPPPPLPGAGIPPPPPLPGMGIPPAP-APPLPPPGTGIPPPPLLPVSGPPLLPQVGSST 1253
Query: 506 ----PVVGITPSQMVANAF 520
V G P + + F
Sbjct: 1254 LPTPQVCGFLPPPLPSGLF 1272
>gi|112734870 hypothetical protein LOC57648 [Homo sapiens]
Length = 1094
Score = 61.6 bits (148), Expect = 2e-09
Identities = 66/238 (27%), Positives = 89/238 (37%), Gaps = 20/238 (8%)
Query: 346 VPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAW---GEPSVPPAAAF 402
V + PGA S S+ +LC SSS A + GP T + P VP +
Sbjct: 616 VTSLRSPGASVSSSLTSLC---SSSSDPAPSDRSGPQILTPLGDRFVIPPHPKVPAPFSP 672
Query: 403 QPGHKRTPSEAERWLEE-------VSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPT 455
P R+P+ A L VS + Q Q Q+ + +P P+
Sbjct: 673 PPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQESPVISKDQSPPPS 732
Query: 456 MPPALQPFPAPVG-PFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQ 514
PP+ P P P P A A +Q P P P PP P + +
Sbjct: 733 PPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPP----PPAPEEQDLSMADFP 788
Query: 515 MVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAP 572
AF S A P+PA G PA S+ + + +P G+P PP PAPAP
Sbjct: 789 PPEEAFFSVAS--PEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAP 844
Score = 44.3 bits (103), Expect = 3e-04
Identities = 81/355 (22%), Positives = 117/355 (32%), Gaps = 51/355 (14%)
Query: 248 AAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLEQLVRQGSFR 307
A P +PG AQP + SPG + +++ P + + L G
Sbjct: 599 AGPPASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPSDRSGPQILTPLGDRF 658
Query: 308 GFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEME-PPGAGDSDSINALCTQ 366
P + +PF S + P+ V G V + P + + Q
Sbjct: 659 VIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGPVSTTDASPQSPPTPQTTLTPLQ 718
Query: 367 ISSSFASAGAPAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKA 426
S + +P P PPP+ P PP + E +E S A
Sbjct: 719 ESPVISKDQSPPPSPPPSY-------HPPPPPT-----------KKPEVVVEAPSASETA 760
Query: 427 QQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPF----PAPVGP--------FDAAP 474
++ Q ++Q S+A P PP F P P GP AA
Sbjct: 761 EEPLQDPNWPPPPPPAPEEQDLSMADFP--PPEEAFFSVASPEPAGPSGSPELVSSPAAS 818
Query: 475 AQVAVFL---PPPHMQPPFVPAYPGLG------YPPMPRVPVVGIT-----PSQMVANAF 520
+ A L PP PP P P +P+ VG + P + V
Sbjct: 819 SSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKGGGPPREDVGAPL 878
Query: 521 CSAAQLQPQPATLLGKAGAFPPPAI-PSAPGSQARPRPNGAPWPPEPAPAPAPEL 574
+ + LQ +G G P PA+ PSAP R +G P PAP+ L
Sbjct: 879 VTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGR---ASPVPAPSSGL 930
Score = 41.2 bits (95), Expect = 0.003
Identities = 89/383 (23%), Positives = 133/383 (34%), Gaps = 65/383 (16%)
Query: 239 PDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAGTPVAAGTTAAAIPRRHAPLE 298
P K ++ AAP +A PG VS T A+ +P TT P + +P+
Sbjct: 674 PSKPRSPNPAAPALAAPAVVPGPVSTTDASPQ--------SPPTPQTTLT--PLQESPV- 722
Query: 299 QLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPEMEPPGAGDSD 358
+ + S P S P + + E PS + + P PP + D
Sbjct: 723 -ISKDQSPPPSPPPSYHPPPPPTKKPEVVVEAPSASETAEEPLQDPNWPPPPPPAPEEQD 781
Query: 359 SINALCTQISSSFASAGAPAPGPP---------PATTGTSAWGEPSVPPAAAFQPGHKRT 409
A +F S +P P P PA + +SA PP + P
Sbjct: 782 LSMADFPPPEEAFFSVASPEPAGPSGSPELVSSPAASSSSATALQIQPPGSPDPPPAPPA 841
Query: 410 PSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGP 469
P+ A VAK Q++ + ++ A V P L+ AP G
Sbjct: 842 PAPAS---SAPGHVAKLPQKEPVGCSKGGGPPREDVGAPLVTPSLLQMVRLRSVGAPGG- 897
Query: 470 FDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQ 529
AP P LG P P+ P + A A P
Sbjct: 898 ---APT-------------------PALG-PSAPQKP---------LRRALSGRASPVPA 925
Query: 530 PATLLGKAGAFPPPAIPSAPGSQARPRPNGAPWPPEPAPAPAPELDPFEAQWAALEG--K 587
P++ L A ++ ++ G + +PNG PPE P P P+ A + +G K
Sbjct: 926 PSSGLHAAVRLKACSLAASEGLSS-AQPNG---PPEAEPRP-PQSPASTASFIFSKGSRK 980
Query: 588 ATVEKPSNP-FSGDLQKTFEIEL 609
+E+P +P DLQ+ EL
Sbjct: 981 LQLERPVSPETQADLQRNLVAEL 1003
Score = 40.8 bits (94), Expect = 0.004
Identities = 67/282 (23%), Positives = 100/282 (35%), Gaps = 54/282 (19%)
Query: 231 GRPAEREAPDKKKAEAAAAPTVAPGPAQP--GHVSPTPATTSPGEKGEAGTPVAAGTTAA 288
G P +P + A A PG P +P PA+++PG + G +
Sbjct: 807 GSPELVSSPAASSSSATALQIQPPGSPDPPPAPPAPAPASSAPGHVAKLPQKEPVGCSKG 866
Query: 289 AIPRRH---APLE-----QLVRQGSFRG-----FPAL--SQKNSPFKRQLSLRLNELPST 333
P R APL Q+VR S PAL S P +R LS R + +P+
Sbjct: 867 GGPPREDVGAPLVTPSLLQMVRLRSVGAPGGAPTPALGPSAPQKPLRRALSGRASPVPA- 925
Query: 334 LQRRTDFQVKGTVPEMEPPGAGDSDSINALCTQISSSFASAGAPAPGPPPATTGTSAWGE 393
P +G ++ +++S + A GPP A E
Sbjct: 926 ------------------PSSGLHAAVRLKACSLAASEGLSSAQPNGPPEA--------E 959
Query: 394 PSVPPAAAFQPGHKRTPSEAERWLEE-VSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAP 452
P P + A + + LE VS +A Q+ + + +Q+ QA +P
Sbjct: 960 PRPPQSPASTASFIFSKGSRKLQLERPVSPETQADLQRNLVAELRSISEQRPPQAPKKSP 1019
Query: 453 VPTMPPALQP---FPAPVGPFDAAPAQVAVFLPP----PHMQ 487
P A +P P P P + P + PP PH Q
Sbjct: 1020 KAPPPVARKPSVGVPPPASP--SYPRAEPLTAPPTNGLPHTQ 1059
Score = 38.1 bits (87), Expect = 0.024
Identities = 46/173 (26%), Positives = 61/173 (35%), Gaps = 31/173 (17%)
Query: 429 QQQQQQQQQQQQQQQQQQAASVAPVPTMP-----PALQPFPA---------PVGPFDAAP 474
+++QQ Q + + A AP P P P L P + + P
Sbjct: 526 ERKQQPQLPRPPTTGGSEGAGAAPCPPNPANSWVPGLSPGGSRRPPRSPERTLSPSSGYS 585
Query: 475 AQVAV-FLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQLQPQPA-- 531
+Q LPP + P PA PG PP P +P V+++ S PA
Sbjct: 586 SQSGTPTLPPKGLAGP--PASPGKAQPPKPERVTSLRSPGASVSSSLTSLCSSSSDPAPS 643
Query: 532 --------TLLGKAGAFPP-PAIP---SAPGSQARPRPNGAPWPPEPAPAPAP 572
T LG PP P +P S P S+ R AP PA P P
Sbjct: 644 DRSGPQILTPLGDRFVIPPHPKVPAPFSPPPSKPRSPNPAAPALAAPAVVPGP 696
>gi|21237805 SWI/SNF-related matrix-associated actin-dependent
regulator of chromatin c2 isoform a [Homo sapiens]
Length = 1214
Score = 61.2 bits (147), Expect = 3e-09
Identities = 65/217 (29%), Positives = 86/217 (39%), Gaps = 50/217 (23%)
Query: 406 HKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPA 465
++R A+R + Q+ A+ + +QQ QQ QQQQQ P P +PP QP P
Sbjct: 922 YQRQQLLADRQAFHMEQLKYAEMRARQQHFQQMHQQQQQ-------PPPALPPGSQPIP- 973
Query: 466 PVGPFDAAPAQVAVFLPPPHMQPPFVPAYPGLGYPPMPRVPVVGITPSQMVANAFCSAAQ 525
P G A P V P VPA G G PP + PS+ + A +A
Sbjct: 974 PTGA--AGPPAVHGLAVAP---ASVVPAPAGSGAPP------GSLGPSEQIGQAGSTAGP 1022
Query: 526 LQPQPATLLGKAGAFPPPAIP---------------------SAPGS----QARPRPNGA 560
Q QPA + GA PP P + PGS A P G
Sbjct: 1023 QQQQPAG-APQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMPGAVPGSGHPGVAGNAPLGL 1081
Query: 561 PW-PPEPAPAPAPELDPFEAQWAALEGKATVEKPSNP 596
P+ P P P PAP + PF +L ++ P+ P
Sbjct: 1082 PFGMPPPPPPPAPSIIPF----GSLADSISINLPAPP 1114
Score = 43.9 bits (102), Expect = 4e-04
Identities = 64/249 (25%), Positives = 81/249 (32%), Gaps = 63/249 (25%)
Query: 351 PPGA-GDSDSIN-ALCTQISSSFASAGAPAPG------PPPATTGTSAWGE----PSVPP 398
PPG+ G S+ I A T AGAP PG PPP G S + PS+ P
Sbjct: 1003 PPGSLGPSEQIGQAGSTAGPQQQQPAGAPQPGAVPPGVPPPGPHGPSPFPNQQTPPSMMP 1062
Query: 399 AAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQQQQQQQQQQQQAASVAPVPTMPP 458
A GH A L P PP
Sbjct: 1063 GAVPGSGHPGVAGNAPLGL----------------------------------PFGMPPP 1088
Query: 459 ALQPFPAPVGPFDAAPAQVAVFLPPP------HMQPPFVPAY-------PGLGYPPMPRV 505
P P+ + PF + +++ LP P H PF P + P P +
Sbjct: 1089 PPPPAPSII-PFGSLADSISINLPAPPNLHGHHHHLPFAPGTLPPPNLPVSMANPLHPNL 1147
Query: 506 PVVGITPSQMVANAFCSAAQLQPQPATLLGKAGAFPPPAIPSA-PGSQARPRPNGAPWPP 564
P PS + +A Q PA + G P A P PG+ P P AP P
Sbjct: 1148 PATTTMPSSLPLGPGLGSAAAQ-SPAIVAAVQGNLLPSASPLPDPGTPLPPDPT-APSPG 1205
Query: 565 EPAPAPAPE 573
P P P+
Sbjct: 1206 TVTPVPPPQ 1214
>gi|148277037 AP2 associated kinase 1 [Homo sapiens]
Length = 961
Score = 60.8 bits (146), Expect = 3e-09
Identities = 72/278 (25%), Positives = 95/278 (34%), Gaps = 26/278 (9%)
Query: 233 PAEREAPDKKKAEAAAAPTVAPGPAQPGHVSPTPATTSPGEKGEAG----TPVAAGTTAA 288
P + P+ KA AAA P + T + +P ++ +AG P A
Sbjct: 328 PIPAKLPEPVKASEAAAKKTQPKARLTDPIPTTETSIAPRQRPKAGQTQPNPGILPIQPA 387
Query: 289 AIPRRHAPLEQLVRQGSFRGFPALSQKNSPFKRQLSLRLNELPSTLQRRTDFQVKGTVPE 348
PR+ A ++ + P L + P + + LP T ++ P+
Sbjct: 388 LTPRKRATVQPPPQAAGSSNQPGLLA-SVPQPKPQAPPSQPLPQTQAKQPQAP---PTPQ 443
Query: 349 MEPPGAGDSDSINALCTQISSS--FASAGAPAPGPPPATTGTSA-WGEPSVPPAAAFQPG 405
P A T F PPPA + + + FQ
Sbjct: 444 QTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQQPAGTFYQQQQAQTQQFQAV 503
Query: 406 HKRTPSEAERWLEEVSQVAKAQQ-----QQQQQQQQQQQQQQQ----------QQQAASV 450
H T A VSQ QQ QQQQQQQQQQQQQQ Q A++
Sbjct: 504 HPATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQQQQLATALHQQQLMTQQAAL 563
Query: 451 APVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQP 488
PTM QP P P APAQ P QP
Sbjct: 564 QQKPTMAAGQQPQPQPAAAPQPAPAQEPAIQAPVRQQP 601
Score = 40.0 bits (92), Expect = 0.006
Identities = 56/233 (24%), Positives = 79/233 (33%), Gaps = 38/233 (16%)
Query: 376 APAPGPPPATTGTSAWGEPSVPPAAAFQPGHKRTPSEAERWLEEVSQVAKAQQQQQQQQQ 435
AP P T + P P + + P +A + +A Q + Q
Sbjct: 365 APRQRPKAGQTQPNPGILPIQPALTPRKRATVQPPPQAAGSSNQPGLLASVPQPKPQAPP 424
Query: 436 QQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFL--------PPPHMQ 487
Q Q Q +Q + P P P+ Q P Q +FL PPP Q
Sbjct: 425 SQPLPQTQAKQPQA-PPTPQQTPSTQAQGLPAQAQATPQHQQQLFLKQQQQQQQPPPAQQ 483
Query: 488 PP--------------FVPAYPGLGYPPMPRVPVV--GITPSQMVANAFCSAAQLQPQP- 530
P F +P P + + PVV G + Q++ N + Q Q Q
Sbjct: 484 QPAGTFYQQQQAQTQQFQAVHPATQQPAIAQFPVVSQGGSQQQLMQNFYQQQQQQQQQQQ 543
Query: 531 ----ATLLGKAGAFPPPAI-----PSAPGSQARPRPNGAPWPPEPAPAPAPEL 574
AT L + A A G Q +P+P A P+PAPA P +
Sbjct: 544 QQQLATALHQQQLMTQQAALQQKPTMAAGQQPQPQPAAA---PQPAPAQEPAI 593
>gi|32307126 nuclear receptor coactivator 3 isoform a [Homo sapiens]
Length = 1424
Score = 60.5 bits (145), Expect = 4e-09
Identities = 49/150 (32%), Positives = 67/150 (44%), Gaps = 26/150 (17%)
Query: 385 TTGTSAWGEPSVPPAAAFQPGHKRTPSEAER----------------WLEEVSQVAKAQQ 428
T G +A P + P + Q G A+R +++ Q + QQ
Sbjct: 1199 TAGGAAVMRPMMQPQVSSQQGFLNAQMVAQRSRELLSHHFRQQRVAMMMQQQQQQQQQQQ 1258
Query: 429 QQQQQQQQQQQQQQQQQQAASVAPVPTMPPALQPFPAPVGPFDAAPAQVAVFLPPPHMQP 488
QQQQQQQQQQQQQQQQQQ + +P PP + P+ G A P P Q
Sbjct: 1259 QQQQQQQQQQQQQQQQQQTQAFSP----PPNVTASPSMDGLL-AGPTMPQA----PPQQF 1309
Query: 489 PFVPAYPGLGYPPMPRVPVVGITPSQMVAN 518
P+ P Y G+G P P V P+ M+++
Sbjct: 1310 PYQPNY-GMGQQPDPAFGRVSSPPNAMMSS 1338
>gi|50511947 cajalin 2 isoform b [Homo sapiens]
Length = 510
Score = 60.5 bits (145), Expect = 4e-09
Identities = 38/132 (28%), Positives = 63/132 (47%), Gaps = 8/132 (6%)
Query: 53 KPAYVPEASRPHQ-WQADEDAVRKGTCSFPVRYLGHVEVEESRGMHVCEDAVKKLKAMGR 111
+P AS P Q WQ + + +C + YLG + ++E RG +DA K++A +
Sbjct: 284 RPPNEATASTPVQYWQHHPEKLIFQSCDYKAFYLGSMLIKELRGTESTQDACAKMRANCQ 343
Query: 112 KSVKS-------VLWVSADGLRVVDDKTKDLLVDQTIEKVSFCAPDRNLDKAFSYICRDG 164
KS + +L VS G++ +D K+++ + I +S A D F+YI +D
Sbjct: 344 KSTEQMKKVPTIILSVSYKGVKFIDATNKNIIAEHEIRNISCAAQDPEDLSTFAYITKDL 403
Query: 165 TTRRWICHCFLA 176
+ CH F A
Sbjct: 404 KSNHHYCHVFTA 415
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.130 0.401
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,376,569
Number of Sequences: 37866
Number of extensions: 2213438
Number of successful extensions: 43020
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 594
Number of HSP's successfully gapped in prelim test: 1338
Number of HSP's that attempted gapping in prelim test: 17453
Number of HSP's gapped (non-prelim): 16200
length of query: 609
length of database: 18,247,518
effective HSP length: 108
effective length of query: 501
effective length of database: 14,157,990
effective search space: 7093152990
effective search space used: 7093152990
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (22.0 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.