Guide to the Human Genome
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Search of human proteins with 239741297

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|239741297 PREDICTED: neuroblastoma breakpoint family, member
9 [Homo sapiens]
         (299 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|239741297 PREDICTED: neuroblastoma breakpoint family, member ...   592   e-169
gi|156071420 hypothetical protein LOC728912 [Homo sapiens]            538   e-153
gi|119709825 neuroblastoma breakpoint family, member 11-like [Ho...   538   e-153
gi|29789405 hypothetical protein LOC284565 [Homo sapiens]             530   e-151
gi|157266285 hypothetical protein LOC728936 [Homo sapiens]            530   e-151
gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ...   527   e-150
gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo sap...   527   e-150
gi|92110019 hypothetical protein LOC55672 [Homo sapiens]              526   e-150
gi|83415174 hypothetical protein LOC400818 [Homo sapiens]             525   e-149
gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]         521   e-148
gi|14149997 neuroblastoma breakpoint family, member 3 [Homo sapi...   448   e-126
gi|114158664 hypothetical protein LOC343505 [Homo sapiens]            424   e-119
gi|7657017 hypothetical protein LOC25832 [Homo sapiens]               410   e-115
gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2...   368   e-102
gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1...   368   e-102
gi|221218991 neuroblastoma breakpoint family, member 4 [Homo sap...   368   e-102
gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint fami...   117   1e-26
gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint fami...   114   8e-26
gi|239741281 PREDICTED: Neuroblastoma breakpoint family member 6...   114   8e-26
gi|239752894 PREDICTED: Neuroblastoma breakpoint family member 6...   112   5e-25
gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ...    82   6e-16
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik...    50   2e-06
gi|7657138 golgi integral membrane protein 4 [Homo sapiens]            50   2e-06
gi|148746195 trichohyalin [Homo sapiens]                               50   3e-06
gi|21735548 centrosomal protein 2 [Homo sapiens]                       48   9e-06
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]            48   9e-06
gi|84043963 eukaryotic translation initiation factor 5B [Homo sa...    48   1e-05
gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]     47   2e-05
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li...    47   2e-05
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap...    46   5e-05

>gi|239741297 PREDICTED: neuroblastoma breakpoint family, member 9
           [Homo sapiens]
          Length = 299

 Score =  592 bits (1526), Expect = e-169
 Identities = 299/299 (100%), Positives = 299/299 (100%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL
Sbjct: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPRGNRSQAQQGAAG 299
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPRGNRSQAQQGAAG
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPRGNRSQAQQGAAG 299


>gi|156071420 hypothetical protein LOC728912 [Homo sapiens]
          Length = 790

 Score =  538 bits (1386), Expect = e-153
 Identities = 274/287 (95%), Positives = 277/287 (96%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFRSLKEKCFVTQ+A FLAKQQNKYKY
Sbjct: 197 MVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKY 256

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIKSMLRNE QFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
Sbjct: 257 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 316

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 317 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 376

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL
Sbjct: 377 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 436

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR    S E+  P+
Sbjct: 437 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 483



 Score =  278 bits (710), Expect = 5e-75
 Identities = 145/199 (72%), Positives = 162/199 (81%), Gaps = 12/199 (6%)

Query: 90  EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 149
           +E++QYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA
Sbjct: 15  QEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74

Query: 150 EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEECAI 209
           EGCRLAQHLVQKLSPEND D+DEDVQVE  EKV +SS+PRE+QKAEE +VPEDSLEECAI
Sbjct: 75  EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134

Query: 210 TCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEE 267
           TCSNSHGP DS QPH+  KITFEEDKV+S+L+    SSH   +DA++I+P          
Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILP---------- 184

Query: 268 EKGPVSPRTSVGSSEKGGP 286
             GP S  T+V      GP
Sbjct: 185 VPGPTSSATNVSMVVSAGP 203



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 35/112 (31%), Positives = 49/112 (43%), Gaps = 17/112 (15%)

Query: 169 DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
           D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+R
Sbjct: 598 DMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYR 657

Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
               + EE  +   L               +   + D EEEE++GP  PR S
Sbjct: 658 SAVYSLEEQYLGLAL--------------DVDRIKKDQEEEEDQGPPCPRLS 695



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 61/280 (21%), Positives = 115/280 (41%), Gaps = 49/280 (17%)

Query: 21  NEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECK----------DLIKSM 70
           +E ++ ++AEK Q+  S +E     +      K+  +   EEC           D  +  
Sbjct: 367 DEDVQVEVAEKVQKSSSPREMQKAEE------KEVPEDSLEECAITCSNSHGPYDSNQPH 420

Query: 71  LRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQAL 130
            + ++ F+E+K+   L  +    +++  VH      +   E+  +G  + R+L E  +  
Sbjct: 421 RKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEE- 479

Query: 131 LTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQV----------EVAE 180
              + P +S  +          RLA +  Q  S    + +++ V +          +V +
Sbjct: 480 ---EVPQESWDEGYSTLSIPPERLASY--QSYSSTFHSLEEQQVCMAVDIGRHRWDQVKK 534

Query: 181 KVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVD 237
           + Q+++ PR   E+   +E EV +DSL+ C  T S   G  DS QP+R      E+ ++ 
Sbjct: 535 EDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIG 594

Query: 238 STLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
             +               + E E   E EE++ P  PR S
Sbjct: 595 LAV--------------DMDEIEKYQEVEEDQDPSCPRLS 620


>gi|119709825 neuroblastoma breakpoint family, member 11-like [Homo
           sapiens]
          Length = 790

 Score =  538 bits (1386), Expect = e-153
 Identities = 274/287 (95%), Positives = 277/287 (96%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFRSLKEKCFVTQ+A FLAKQQNKYKY
Sbjct: 197 MVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQNKYKY 256

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIKSMLRNE QFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
Sbjct: 257 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 316

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 317 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 376

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL
Sbjct: 377 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 436

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR    S E+  P+
Sbjct: 437 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 483



 Score =  279 bits (713), Expect = 2e-75
 Identities = 146/199 (73%), Positives = 162/199 (81%), Gaps = 12/199 (6%)

Query: 90  EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 149
           EE++QYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA
Sbjct: 15  EEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74

Query: 150 EGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEECAI 209
           EGCRLAQHLVQKLSPEND D+DEDVQVE  EKV +SS+PRE+QKAEE +VPEDSLEECAI
Sbjct: 75  EGCRLAQHLVQKLSPENDEDEDEDVQVEEDEKVLESSAPREVQKAEESKVPEDSLEECAI 134

Query: 210 TCSNSHGPYDSNQPHRKTKITFEEDKVDSTLI--GSSSHVEWEDAVHIIPENESDDEEEE 267
           TCSNSHGP DS QPH+  KITFEEDKV+S+L+    SSH   +DA++I+P          
Sbjct: 135 TCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILP---------- 184

Query: 268 EKGPVSPRTSVGSSEKGGP 286
             GP S  T+V      GP
Sbjct: 185 VPGPTSSATNVSMVVSAGP 203



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 35/112 (31%), Positives = 49/112 (43%), Gaps = 17/112 (15%)

Query: 169 DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
           D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+R
Sbjct: 598 DMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYR 657

Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
               + EE  +   L               +   + D EEEE++GP  PR S
Sbjct: 658 SAVYSLEEQYLGLAL--------------DVDRIKKDQEEEEDQGPPCPRLS 695



 Score = 40.0 bits (92), Expect = 0.002
 Identities = 61/280 (21%), Positives = 115/280 (41%), Gaps = 49/280 (17%)

Query: 21  NEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECK----------DLIKSM 70
           +E ++ ++AEK Q+  S +E     +      K+  +   EEC           D  +  
Sbjct: 367 DEDVQVEVAEKVQKSSSPREMQKAEE------KEVPEDSLEECAITCSNSHGPYDSNQPH 420

Query: 71  LRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQAL 130
            + ++ F+E+K+   L  +    +++  VH      +   E+  +G  + R+L E  +  
Sbjct: 421 RKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEE- 479

Query: 131 LTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQV----------EVAE 180
              + P +S  +          RLA +  Q  S    + +++ V +          +V +
Sbjct: 480 ---EVPQESWDEGYSTLSIPPERLASY--QSYSSTFHSLEEQQVCMAVDIGRHRWDQVKK 534

Query: 181 KVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVD 237
           + Q+++ PR   E+   +E EV +DSL+ C  T S   G  DS QP+R      E+ ++ 
Sbjct: 535 EDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIG 594

Query: 238 STLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
             +               + E E   E EE++ P  PR S
Sbjct: 595 LAV--------------DMDEIEKYQEVEEDQDPSCPRLS 620


>gi|29789405 hypothetical protein LOC284565 [Homo sapiens]
          Length = 670

 Score =  530 bits (1366), Expect = e-151
 Identities = 267/287 (93%), Positives = 275/287 (95%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFR+LKEKCF+TQLAGFLA +Q KYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIK MLRNE QFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KVQKSS+PREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR    S E+  P+
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 287



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 17/112 (15%)

Query: 169 DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
           D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S+     D  QP+ 
Sbjct: 402 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461

Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
               + EE  +   L               +   + D EEEE++GP  PR S
Sbjct: 462 SAVYSLEEQYLGLALA--------------VDRIKKDQEEEEDQGPPCPRLS 499



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 17/104 (16%)

Query: 177 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 233
           +V ++ Q+++ PR   E+   +E EV +DSL+ C  T S      DS QP+R      E+
Sbjct: 335 QVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 394

Query: 234 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
            +V   +               + E E   E EE++ P  PR S
Sbjct: 395 QRVGLAI--------------DMDEIEKYQEVEEDQDPSCPRLS 424



 Score = 35.0 bits (79), Expect = 0.080
 Identities = 42/163 (25%), Positives = 69/163 (42%), Gaps = 27/163 (16%)

Query: 90  EELRQYKVLVHSQERELTQLREKLREGRDAS-------RSLNEHLQALLTPD--EPDKSQ 140
           +E+ +Y+ +   Q+    +L  +L + ++         R  +     L  PD  +P  S 
Sbjct: 404 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSA 463

Query: 141 GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197
              L+EQ   G  LA   ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 464 VYSLEEQYL-GLALAVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 508

Query: 198 EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           EV +DSL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 509 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 551



 Score = 32.3 bits (72), Expect = 0.52
 Identities = 18/50 (36%), Positives = 26/50 (52%)

Query: 191 MQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           + + EE EV +DSL+ C  T S      DS Q +R    +FEE+ +   L
Sbjct: 595 LMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFAL 644


>gi|157266285 hypothetical protein LOC728936 [Homo sapiens]
          Length = 670

 Score =  530 bits (1366), Expect = e-151
 Identities = 267/287 (93%), Positives = 275/287 (95%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFR+LKEKCF+TQLAGFLA +Q KYKY
Sbjct: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIK MLRNE QFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRL QHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDVQVEVAE 180

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KVQKSS+PREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPH+KTKITFEEDKVDSTL
Sbjct: 181 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVDSTL 240

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR    S E+  P+
Sbjct: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 287



 Score = 42.4 bits (98), Expect = 5e-04
 Identities = 34/112 (30%), Positives = 49/112 (43%), Gaps = 17/112 (15%)

Query: 169 DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
           D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S+     D  QP+ 
Sbjct: 402 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYS 461

Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
               + EE  +   L               +   + D EEEE++GP  PR S
Sbjct: 462 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLS 499



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 30/104 (28%), Positives = 47/104 (45%), Gaps = 17/104 (16%)

Query: 177 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 233
           +V ++ Q+++ PR   E+   +E EV +DSL+ C  T S      DS QP+R      E+
Sbjct: 335 QVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 394

Query: 234 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
            +V   +               + E E   E EE++ P  PR S
Sbjct: 395 QRVGLAI--------------DMDEIEKYQEVEEDQDPSCPRLS 424



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 41/163 (25%), Positives = 68/163 (41%), Gaps = 27/163 (16%)

Query: 90  EELRQYKVLVHSQERELTQLREKLREGRDAS-------RSLNEHLQALLTPD--EPDKSQ 140
           +E+ +Y+ +   Q+    +L  +L + ++         R  +     L  PD  +P  S 
Sbjct: 404 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQPYSSA 463

Query: 141 GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197
              L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 464 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 508

Query: 198 EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           EV +DSL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 509 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 551



 Score = 31.6 bits (70), Expect = 0.89
 Identities = 18/50 (36%), Positives = 26/50 (52%)

Query: 191 MQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           + + EE EV +DSL+ C  T S      DS Q +R    +FEE+ +   L
Sbjct: 595 LMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFAL 644


>gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo
           sapiens]
          Length = 4621

 Score =  527 bits (1358), Expect = e-150
 Identities = 267/287 (93%), Positives = 274/287 (95%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFR+LKE+CFVTQLAGFLA QQ KYKY
Sbjct: 272 MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQLAGFLANQQKKYKY 331

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIKSMLRNE QFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 332 EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 391

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVE+AE
Sbjct: 392 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVELAE 451

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KVQKSS+PREMQKAEEKEVPEDS EECAIT SNSHGPYDSNQPHRKTKITFEEDKVDSTL
Sbjct: 452 KVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR    S E+  P+
Sbjct: 512 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 558



 Score =  439 bits (1128), Expect = e-123
 Identities = 230/288 (79%), Positives = 245/288 (85%), Gaps = 12/288 (4%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQF +LKE+CFVTQLAGFLA QQ KY Y
Sbjct: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFVTQLAGFLANQQKKYNY 60

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIK MLRNE QFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLT DEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE AE
Sbjct: 121 RSLNEHLQALLTLDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KVQKSS+PRE+QK EE +VPEDSLEECAITCSNSHGP DSNQPH+  KITFEED+V+STL
Sbjct: 181 KVQKSSAPREVQKTEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGP 286
           +    SSH E +DA++I+P            GP S  T+V      GP
Sbjct: 241 VVDRESSHDECQDALNILP----------VPGPTSSATNVSMVVSAGP 278



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 17/112 (15%)

Query: 169  DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 2625 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2684

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                + EE  +   L               +   + D EEEE++GP  PR S
Sbjct: 2685 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLS 2722



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 17/112 (15%)

Query: 169  DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 4352 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 4411

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                + EE  +   L               +   + D EEEE++GP  PR S
Sbjct: 4412 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLS 4449



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 2817 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL-------- 2868

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   +   + D EEEE++GP  PR S
Sbjct: 2869 ------DVDRTKKDQEEEEDQGPPCPRLS 2891



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 2986 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL-------- 3037

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   +   + D EEEE++GP  PR S
Sbjct: 3038 ------DVDRTKKDQEEEEDQGPPCPRLS 3060



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 3155 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL-------- 3206

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   +   + D EEEE++GP  PR S
Sbjct: 3207 ------DVDRTKKDQEEEEDQGPPCPRLS 3229



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 17/104 (16%)

Query: 177 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 233
           +V ++ Q+++ PR   E+   +  EV +DSL+ C  T S      DS QP+R      E+
Sbjct: 606 QVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 665

Query: 234 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
            ++   +               + E E   E EE++ P  PR S
Sbjct: 666 QRIGLAV--------------DMDEIEKYQEVEEDQDPSCPRLS 695



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90  EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
           +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 675 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 734

Query: 146 EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
               E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 735 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 784

Query: 203 SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
           SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 785 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 844

Query: 263 -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                 E EE++ P  PR S    ++ GP
Sbjct: 845 RRRGRKEGEEDQNPPCPRLSRELLDEKGP 873



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 919  DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 978

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 979  VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 1028

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
            SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 1029 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 1088

Query: 263  -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                  E EE++ P  PR S    ++ GP
Sbjct: 1089 RRRGRKEGEEDQNPPCPRLSRELLDEKGP 1117



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 1163 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1222

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 1223 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 1272

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
            SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 1273 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 1332

Query: 263  -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                  E EE++ P  PR S    ++ GP
Sbjct: 1333 RRRGRKEGEEDQNPPCPRLSRELLDEKGP 1361



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 1407 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1466

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 1467 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 1516

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
            SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 1517 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 1576

Query: 263  -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                  E EE++ P  PR S    ++ GP
Sbjct: 1577 RRRGRKEGEEDQNPPCPRLSRELLDEKGP 1605



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 1651 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1710

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 1711 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 1760

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
            SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 1761 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 1820

Query: 263  -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                  E EE++ P  PR S    ++ GP
Sbjct: 1821 RRRGRKEGEEDQNPPCPRLSRELLDEKGP 1849



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 1895 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1954

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 1955 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 2004

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
            SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 2005 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 2064

Query: 263  -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                  E EE++ P  PR S    ++ GP
Sbjct: 2065 RRRGRKEGEEDQNPPCPRLSRELLDEKGP 2093



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 2139 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2198

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 2199 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 2248

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
            SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 2249 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 2308

Query: 263  -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                  E EE++ P  PR S    ++ GP
Sbjct: 2309 RRRGRKEGEEDQNPPCPRLSRELLDEKGP 2337



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 2383 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2442

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 2443 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 2492

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
            SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 2493 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 2552

Query: 263  -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                  E EE++ P  PR S    ++ GP
Sbjct: 2553 RRRGRKEGEEDQNPPCPRLSRELLDEKGP 2581



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 3378 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 3437

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 3438 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 3487

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
            SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 3488 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 3547

Query: 263  -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                  E EE++ P  PR S    ++ GP
Sbjct: 3548 RRRGRKEGEEDQNPPCPRLSRELLDEKGP 3576



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 3622 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 3681

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 3682 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 3731

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
            SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 3732 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 3791

Query: 263  -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                  E EE++ P  PR S    ++ GP
Sbjct: 3792 RRRGRKEGEEDQNPPCPRLSRELLDEKGP 3820



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 4110 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 4169

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 4170 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 4219

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
            SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 4220 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 4279

Query: 263  -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                  E EE++ P  PR S    ++ GP
Sbjct: 4280 RRRGRKEGEEDQNPPCPRLSRELLDEKGP 4308



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 1109 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 1160

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 1161 ------DMDEIEKYQEVEEDQDPSCPRLS 1183



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 1597 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 1648

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 1649 ------DMDEIEKYQEVEEDQDPSCPRLS 1671



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 5/103 (4%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       +
Sbjct: 3230 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 3289

Query: 249  WEDAVHIIPENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286
             +        ++ +      E EE++ P  PR S    ++ GP
Sbjct: 3290 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 3332



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 3324 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 3375

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 3376 ------DMDEIEKYQEVEEDQDPSCPRLS 3398



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 3568 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 3619

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 3620 ------DMDEIEKYQEVEEDQDPSCPRLS 3642



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 3812 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 3863

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 3864 ------DMDEIEKYQEVEEDQDPSCPRLS 3886



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 4056 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 4107

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 4108 ------DMDEIEKYQEVEEDQDPSCPRLS 4130



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 4300 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 4351

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 4352 ------DMDEIEKYQEVEEDQDPSCPRLS 4374



 Score = 32.3 bits (72), Expect = 0.52
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 3866 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 3925

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 3926 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 3975

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
            SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 3976 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 4035

Query: 263  -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                  E EE++ P  PR S    ++ GP
Sbjct: 4036 RRRGRKEGEEDQTPPCPRLSRELLDEKGP 4064



 Score = 31.6 bits (70), Expect = 0.89
 Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 17/158 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 2627 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2686

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 2687 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 2736

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
            SL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 2737 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 2774



 Score = 31.6 bits (70), Expect = 0.89
 Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 17/158 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 4354 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 4413

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 4414 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 4463

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
            SL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 4464 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 4501



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 19/52 (36%), Positives = 27/52 (51%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 2892 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 2943



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 19/52 (36%), Positives = 27/52 (51%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 3061 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 3112



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 3/64 (4%)

Query: 180  EKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV 236
            E+ Q    PR    + + EE EV +DSL+ C  T S      DS Q +R    +FEE  +
Sbjct: 4532 EEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHI 4591

Query: 237  DSTL 240
               L
Sbjct: 4592 SFAL 4595



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 14/89 (15%)

Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
           RE+   +  EV +DSL+    T S      DS QP+R      E+ +V   +        
Sbjct: 865 RELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 916

Query: 249 WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                  + E E   E EE++ P  PR S
Sbjct: 917 ------DMDEIEKYQEVEEDQDPSCPRLS 939



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+    T S      DS QP+R      E+ +V   +        
Sbjct: 1353 RELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 1404

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 1405 ------DMDEIEKYQEVEEDQDPSCPRLS 1427



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+    T S      DS QP+R      E+ +V   +        
Sbjct: 1841 RELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 1892

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 1893 ------DMDEIEKYQEVEEDQDPSCPRLS 1915



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+    T S      DS QP+R      E+ +V   +        
Sbjct: 2085 RELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 2136

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 2137 ------DMDEIEKYQEVEEDQDPSCPRLS 2159



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+    T S      DS QP+R      E+ +V   +        
Sbjct: 2329 RELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 2380

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 2381 ------DMDEIEKYQEVEEDQDPSCPRLS 2403



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+    T S      DS QP+R      E+ +V   +        
Sbjct: 2573 RELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 2624

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 2625 ------DMDEIEKYQEVEEDQDPSCPRLS 2647


>gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo
           sapiens]
          Length = 3815

 Score =  527 bits (1358), Expect = e-150
 Identities = 267/287 (93%), Positives = 274/287 (95%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGPLSSEKAEMNILEINEKL PQLAEKKQQFR+LKE+CFVTQLAGFLA QQ KYKY
Sbjct: 21  MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQLAGFLANQQKKYKY 80

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIKSMLRNE QFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 81  EECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 140

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVE+AE
Sbjct: 141 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVELAE 200

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KVQKSS+PREMQKAEEKEVPEDS EECAIT SNSHGPYDSNQPHRKTKITFEEDKVDSTL
Sbjct: 201 KVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 260

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR    S E+  P+
Sbjct: 261 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 307



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 17/112 (15%)

Query: 169 DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
           D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 666 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 725

Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
               + EE  +   L               +   + D EEEE++GP  PR S
Sbjct: 726 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLS 763



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 17/112 (15%)

Query: 169  DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 910  DVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 969

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                + EE  +   L               +   + D EEEE++GP  PR S
Sbjct: 970  SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLS 1007



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 17/112 (15%)

Query: 169  DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 2393 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2452

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                + EE  +   L               +   + D EEEE++GP  PR S
Sbjct: 2453 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLS 2490



 Score = 43.1 bits (100), Expect = 3e-04
 Identities = 34/112 (30%), Positives = 48/112 (42%), Gaps = 17/112 (15%)

Query: 169  DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 2806 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2865

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                + EE  +   L               +   + D EEEE++GP  PR S
Sbjct: 2866 SAVYSLEEQYLGLALD--------------VDRTKKDQEEEEDQGPPCPRLS 2903



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 1102 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL-------- 1153

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   +   + D EEEE++GP  PR S
Sbjct: 1154 ------DVDRTKKDQEEEEDQGPPCPRLS 1176



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 1271 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL-------- 1322

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   +   + D EEEE++GP  PR S
Sbjct: 1323 ------DVDRTKKDQEEEEDQGPPCPRLS 1345



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 1440 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL-------- 1491

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   +   + D EEEE++GP  PR S
Sbjct: 1492 ------DVDRTKKDQEEEEDQGPPCPRLS 1514



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 2585 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL-------- 2636

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   +   + D EEEE++GP  PR S
Sbjct: 2637 ------DVDRTKKDQEEEEDQGPPCPRLS 2659



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 2998 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL-------- 3049

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   +   + D EEEE++GP  PR S
Sbjct: 3050 ------DVDRTKKDQEEEEDQGPPCPRLS 3072



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 3167 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL-------- 3218

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   +   + D EEEE++GP  PR S
Sbjct: 3219 ------DVDRTKKDQEEEEDQGPPCPRLS 3241



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 27/89 (30%), Positives = 38/89 (42%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 3336 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL-------- 3387

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   +   + D EEEE++GP  PR S
Sbjct: 3388 ------DVDRTKKDQEEEEDQGPPCPRLS 3410



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 28/104 (26%), Positives = 46/104 (44%), Gaps = 17/104 (16%)

Query: 177 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 233
           +V ++ Q+++ PR   E+   +  EV +DSL+ C  T S      DS QP+R      E+
Sbjct: 355 QVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 414

Query: 234 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
            ++   +               + E E   E EE++ P  PR S
Sbjct: 415 QRIGLAV--------------DMDEIEKYQEVEEDQDPSCPRLS 444



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90  EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
           +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 424 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 483

Query: 146 EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
               E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 484 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 533

Query: 203 SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
           SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 534 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 593

Query: 263 -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                 E EE++ P  PR S    ++ GP
Sbjct: 594 RRRGRKEGEEDQNPPCPRLSRELLDEKGP 622



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 1663 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1722

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 1723 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 1772

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
            SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 1773 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 1832

Query: 263  -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                  E EE++ P  PR S    ++ GP
Sbjct: 1833 RRRGRKEGEEDQNPPCPRLSRELLDEKGP 1861



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 1907 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1966

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 1967 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 2016

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
            SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 2017 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 2076

Query: 263  -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                  E EE++ P  PR S    ++ GP
Sbjct: 2077 RRRGRKEGEEDQNPPCPRLSRELLDEKGP 2105



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 2151 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2210

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 2211 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 2260

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
            SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 2261 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 2320

Query: 263  -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                  E EE++ P  PR S    ++ GP
Sbjct: 2321 RRRGRKEGEEDQNPPCPRLSRELLDEKGP 2349



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 47/209 (22%), Positives = 82/209 (39%), Gaps = 22/209 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 3559 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 3618

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 3619 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 3668

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESD 262
            SL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++ +
Sbjct: 3669 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKE 3728

Query: 263  -----DEEEEEKGPVSPRTSVGSSEKGGP 286
                  E EE++ P  PR S    ++ GP
Sbjct: 3729 RRRGRKEGEEDQNPPCPRLSRELLDEKGP 3757



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
           RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 614 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 665

Query: 249 WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                  + E E   E EE++ P  PR S
Sbjct: 666 ------DMDEIEKYQEVEEDQDPSCPRLS 688



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 5/103 (4%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       +
Sbjct: 1515 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 1574

Query: 249  WEDAVHIIPENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286
             +        ++ +      E EE++ P  PR S    ++ GP
Sbjct: 1575 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 1617



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 1609 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 1660

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 1661 ------DMDEIEKYQEVEEDQDPSCPRLS 1683



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 1853 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 1904

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 1905 ------DMDEIEKYQEVEEDQDPSCPRLS 1927



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 2341 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 2392

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 2393 ------DMDEIEKYQEVEEDQDPSCPRLS 2415



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 5/103 (4%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       +
Sbjct: 2660 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 2719

Query: 249  WEDAVHIIPENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286
             +        ++ +      E EE++ P  PR S    ++ GP
Sbjct: 2720 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 2762



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 2754 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 2805

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 2806 ------DMDEIEKYQEVEEDQDPSCPRLS 2828



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 28/103 (27%), Positives = 45/103 (43%), Gaps = 5/103 (4%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       +
Sbjct: 3411 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKK 3470

Query: 249  WEDAVHIIPENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286
             +        ++ +      E EE++ P  PR S    ++ GP
Sbjct: 3471 GKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 3513



 Score = 32.3 bits (72), Expect = 0.52
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 14/89 (15%)

Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
           RE+   +E EV +DSL+ C  T S      D  QP+     + EE  +   L        
Sbjct: 858 RELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL-------- 909

Query: 249 WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                  + E E   E EE++ P  PR S
Sbjct: 910 ------DVDEIEKYQEVEEDQDPSCPRLS 932



 Score = 32.3 bits (72), Expect = 0.52
 Identities = 40/169 (23%), Positives = 67/169 (39%), Gaps = 17/169 (10%)

Query: 79   EEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----D 134
            EE+        +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    +
Sbjct: 901  EEQYLGLALDVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLE 960

Query: 135  EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EM 191
             PD  Q         E     Q+L   L  +    D E+      E+ Q    PR   E+
Sbjct: 961  LPDLGQPYSSAVYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSREL 1010

Query: 192  QKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
             +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 1011 LEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 1059



 Score = 31.6 bits (70), Expect = 0.89
 Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 17/158 (10%)

Query: 90  EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
           +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 668 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 727

Query: 146 EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
               E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 728 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 777

Query: 203 SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           SL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 778 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 815



 Score = 31.6 bits (70), Expect = 0.89
 Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 17/158 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 2395 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2454

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 2455 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 2504

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
            SL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 2505 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 2542



 Score = 31.6 bits (70), Expect = 0.89
 Identities = 38/158 (24%), Positives = 64/158 (40%), Gaps = 17/158 (10%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTP----DEPDKSQGQDLQ 145
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP    + PD  Q     
Sbjct: 2808 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2867

Query: 146  EQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPED 202
                E     Q+L   L  +    D E+      E+ Q    PR   E+ +  E EV +D
Sbjct: 2868 VYSLE----EQYLGLALDVDRTKKDQEE------EEDQGPPCPRLSRELLEVVEPEVLQD 2917

Query: 203  SLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
            SL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 2918 SLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 2955



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 19/52 (36%), Positives = 27/52 (51%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 1177 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 1228



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 19/52 (36%), Positives = 27/52 (51%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 1346 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 1397



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 19/52 (36%), Positives = 27/52 (51%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 3073 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 3124



 Score = 31.2 bits (69), Expect = 1.2
 Identities = 19/52 (36%), Positives = 27/52 (51%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
            RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 3242 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 3293



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 17/48 (35%), Positives = 24/48 (50%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV 236
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V
Sbjct: 3749 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV 3796



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+    T S      DS QP+R      E+ +V   +        
Sbjct: 2097 RELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 2148

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 2149 ------DMDEIEKYQEVEEDQDPSCPRLS 2171



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 25/89 (28%), Positives = 36/89 (40%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+    T S      DS QP+R      E+ +V   +        
Sbjct: 3505 RELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAV-------- 3556

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 3557 ------DMDEIEKYQEVEEDQDPSCPRLS 3579


>gi|92110019 hypothetical protein LOC55672 [Homo sapiens]
          Length = 1214

 Score =  526 bits (1356), Expect = e-150
 Identities = 267/287 (93%), Positives = 274/287 (95%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGPLSSEKAEMNILE+NEKLRPQLAEKKQQFR+LKEKCFVTQLA FLA QQNKYKY
Sbjct: 543 MVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLACFLANQQNKYKY 602

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIKS+LRNE QFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
Sbjct: 603 EECKDLIKSVLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 662

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLN+HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQ L QKLSPENDND DEDVQVEVAE
Sbjct: 663 RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDNDHDEDVQVEVAE 722

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KVQKSS+PREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL
Sbjct: 723 KVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 782

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR    S E+  P+
Sbjct: 783 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 829



 Score =  449 bits (1156), Expect = e-126
 Identities = 234/288 (81%), Positives = 250/288 (86%), Gaps = 12/288 (4%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGPLSSEKAEMNILE+NEKLRPQLAEKKQQFR+LKEKCFVTQLAGFLA QQNKYKY
Sbjct: 272 MVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKY 331

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EEC+DLIKSMLRNE QFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
Sbjct: 332 EECEDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 391

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLN+HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE AE
Sbjct: 392 RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 451

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KV +SS+PRE+QKAEE +VPEDSLEECAITCSNSHGP DSNQPH+   ITFEEDKV+S L
Sbjct: 452 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSAL 511

Query: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGP 286
           +    SSH E +DAV+I+P            GP S  T+V      GP
Sbjct: 512 VVDRESSHDECQDAVNILP----------VPGPTSSATNVSMVVSAGP 549



 Score =  441 bits (1135), Expect = e-124
 Identities = 231/288 (80%), Positives = 246/288 (85%), Gaps = 12/288 (4%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGP SSEKAE NILEINEKLRPQLAE KQQFR+LKEKCFVTQLAGFLA +Q KYKY
Sbjct: 1   MVVSAGPWSSEKAETNILEINEKLRPQLAENKQQFRNLKEKCFVTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIK MLRNE QFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLN+HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE AE
Sbjct: 121 RSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KV +SS+PRE+QKAEE +VPEDSLEECAITCSNSHGP DSNQPH+   ITFEEDKV+STL
Sbjct: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVNSTL 240

Query: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGP 286
           +    SSH E +DAV+I+P            GP S  T+V      GP
Sbjct: 241 VVDRESSHDECQDAVNILP----------VPGPTSSATNVSMVVSAGP 278



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 35/112 (31%), Positives = 49/112 (43%), Gaps = 17/112 (15%)

Query: 169  DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+R
Sbjct: 944  DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYR 1003

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                + EE  +   L               +   + D EEEE++GP  PR S
Sbjct: 1004 SAVYSLEEQYLGLAL--------------DVDRIKKDQEEEEDQGPPCPRLS 1041



 Score = 34.7 bits (78), Expect = 0.10
 Identities = 30/104 (28%), Positives = 46/104 (44%), Gaps = 17/104 (16%)

Query: 177 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 233
           +V ++ Q+++ PR   E+   +  EV +DSL+ C  T S      DS QP+R      E+
Sbjct: 877 QVKKEDQEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQ 936

Query: 234 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
            +V   L               + E E   E EE++ P  PR S
Sbjct: 937 QRVGWAL--------------DMDEIEKYQEVEEDQDPSCPRLS 966



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 29/91 (31%), Positives = 43/91 (47%), Gaps = 13/91 (14%)

Query: 180  EKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV 236
            E+ Q    PR    + + EE EV +DSL+ C  T S      DS Q +R    +FEE  +
Sbjct: 1125 EEDQNPPCPRLSGMLMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHI 1184

Query: 237  D---------STLIGSSSHVEWEDAVHIIPE 258
                       TL+G+S H+ ++  V I P+
Sbjct: 1185 SFALDVDNRFLTLMGTSLHLVFQMGV-IFPQ 1214



 Score = 31.6 bits (70), Expect = 0.89
 Identities = 39/163 (23%), Positives = 68/163 (41%), Gaps = 27/163 (16%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P +S 
Sbjct: 946  DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYRSA 1005

Query: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +A E 
Sbjct: 1006 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEAVEP 1050

Query: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
            EV +DSL+ C  T S+     DS  P+  +    EE  V  +L
Sbjct: 1051 EVLQDSLDRCYSTPSSCLEQPDSCLPYGSSFYALEEKHVGFSL 1093


>gi|83415174 hypothetical protein LOC400818 [Homo sapiens]
          Length = 942

 Score =  525 bits (1353), Expect = e-149
 Identities = 268/287 (93%), Positives = 275/287 (95%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFR+LKEKCF+TQLAGFLA QQNKYKY
Sbjct: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQNKYKY 331

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIK MLRNE QFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDAS
Sbjct: 332 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDAS 391

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDD+EDVQVEVAE
Sbjct: 392 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAE 451

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KVQKSS+PREMQKAEEKEVPEDSLEECAIT SNSHGPYDSNQPHRKTKITFEEDKVDSTL
Sbjct: 452 KVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287
           IGSSSHVE EDAVHIIPENESDDEEEEEKGPVSPR    S E+  P+
Sbjct: 512 IGSSSHVEREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 558



 Score =  431 bits (1107), Expect = e-121
 Identities = 225/288 (78%), Positives = 244/288 (84%), Gaps = 12/288 (4%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQF +LKE+CF+TQLAGFLA +Q KYKY
Sbjct: 1   MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIK MLRNE QFKEEKLAEQLKQAEELRQYKVLVHSQERELTQL+EKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE  E
Sbjct: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEDE 180

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KV +S +PRE+QKAEE +V EDSLEECAITCSNSHGP DSNQPH+  KITFEED+V+STL
Sbjct: 181 KVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGP 286
           +    SSH E +DA++I+P            GP S  T+V      GP
Sbjct: 241 VVDRESSHDECQDALNILP----------VPGPTSSATNVSMVVSAGP 278



 Score = 36.2 bits (82), Expect = 0.036
 Identities = 33/112 (29%), Positives = 46/112 (41%), Gaps = 17/112 (15%)

Query: 169 DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
           D DE  + +  E+ Q  S PR   E+   +E EV +DSL     T S      D  QP+ 
Sbjct: 673 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQPYS 732

Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
               + EE  +   L               +   + D EEEE++GP  PR S
Sbjct: 733 SAVYSLEEQYLGLALD--------------LDRIKKDQEEEEDQGPPCPRLS 770



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 29/104 (27%), Positives = 45/104 (43%), Gaps = 17/104 (16%)

Query: 177 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 233
           +V ++ Q+++ PR   E+   +  EV +DSL  C  T S      DS QP+R      E+
Sbjct: 606 QVKKEDQEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQ 665

Query: 234 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
            +V   +               + E E   E EE++ P  PR S
Sbjct: 666 QRVGLAV--------------DMDEIEKYQEVEEDQDPSCPRLS 695



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 19/52 (36%), Positives = 27/52 (51%)

Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 771 RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSWQPYGSSFYALEEKHVGFSL 822



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 22/64 (34%), Positives = 30/64 (46%), Gaps = 3/64 (4%)

Query: 180 EKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV 236
           E+ Q    PR    + + EE EV +DSL+ C  T S      DS Q +R    +FEE  +
Sbjct: 853 EEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEEQHI 912

Query: 237 DSTL 240
              L
Sbjct: 913 SFAL 916


>gi|224589132 hypothetical protein LOC100132406 [Homo sapiens]
          Length = 3628

 Score =  521 bits (1343), Expect = e-148
 Identities = 265/287 (92%), Positives = 273/287 (95%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFR+LKEKCF+TQL+GFLA QQ KYKY
Sbjct: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGFLANQQKKYKY 331

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIK MLRNE QFKEEKLAEQLKQAEELRQYKVLVH+QERELTQL+EKLREGRDAS
Sbjct: 332 EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDAS 391

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLNEHLQALLTP EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE
Sbjct: 392 RSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 451

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KVQKSS+PREMQKAEEKEVPEDSLEECAIT SNSHG YDSNQPHRKTKITFEEDKVDSTL
Sbjct: 452 KVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTL 511

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287
           IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPR    S E+  P+
Sbjct: 512 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 558



 Score =  439 bits (1130), Expect = e-123
 Identities = 230/288 (79%), Positives = 247/288 (85%), Gaps = 12/288 (4%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGP SSEKAEMNILEINE LRPQLAEKKQQFR+LKEKCF+TQLAGFLA +Q KYKY
Sbjct: 1   MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGFLANRQKKYKY 60

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIK MLRNE QFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS
Sbjct: 61  EECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSL EHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND D+DEDVQVE AE
Sbjct: 121 RSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAE 180

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KV +SS+PRE+QKAEE +VPEDSLEECAITCSNSHGP DSNQPH+  KITFEED+V+STL
Sbjct: 181 KVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVNSTL 240

Query: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGP 286
           +    SSH E +DA++I+P            GP S  T+V      GP
Sbjct: 241 VVDRESSHDECQDALNILP----------VPGPTSSATNVSMVVSAGP 278



 Score = 38.5 bits (88), Expect = 0.007
 Identities = 53/229 (23%), Positives = 92/229 (40%), Gaps = 24/229 (10%)

Query: 72   RNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS---RSLNEHLQ 128
            R+     E++        +E+ +Y+ +   Q+    +L  +L + ++      SLN    
Sbjct: 1389 RSAFYVLEQQRVGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYS 1448

Query: 129  A----LLTPD--EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKV 182
                 L  PD  +P  S    L+EQ   G  L    ++K   E + D+D+D         
Sbjct: 1449 TPSGYLELPDLGQPYSSAVYSLEEQYL-GLALDVDRIKK-DQEEEEDEDQDPPCPRLS-- 1504

Query: 183  QKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIG 242
                  RE+ +  E EV +DSL+ C  T S+     DS QP+  +    EE+ V  +L  
Sbjct: 1505 ------RELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 1558

Query: 243  SSSHVEWEDAVHIIPENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286
                 + +        ++ +      E EE++ P  PR S    ++ GP
Sbjct: 1559 GEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 1607



 Score = 36.6 bits (83), Expect = 0.028
 Identities = 33/112 (29%), Positives = 47/112 (41%), Gaps = 17/112 (15%)

Query: 169  DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
            D DE  + +  E+ Q  S PR   E+   +  EV +DSL+ C  T S      DS QP+R
Sbjct: 3115 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYR 3174

Query: 226  KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                  E+ +V   +               + E E   E EE++ P  PR S
Sbjct: 3175 SAFYILEQQRVGLAV--------------DMDEIEKYQEVEEDQDPSCPRLS 3212



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 48/214 (22%), Positives = 86/214 (40%), Gaps = 32/214 (14%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 1653 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1712

Query: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 1713 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 1757

Query: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257
            EV +DSL+ C  T S+     DS QP+  +    EE+ V  +L       + +       
Sbjct: 1758 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGR 1817

Query: 258  ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286
             ++ +      E EE++ P  PR S    ++ GP
Sbjct: 1818 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 1851



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 48/214 (22%), Positives = 86/214 (40%), Gaps = 32/214 (14%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 1897 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1956

Query: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 1957 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 2001

Query: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257
            EV +DSL+ C  T S+     DS QP+  +    EE+ V  +L       + +       
Sbjct: 2002 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGR 2061

Query: 258  ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286
             ++ +      E EE++ P  PR S    ++ GP
Sbjct: 2062 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 2095



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 48/214 (22%), Positives = 86/214 (40%), Gaps = 32/214 (14%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 2141 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2200

Query: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 2201 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 2245

Query: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257
            EV +DSL+ C  T S+     DS QP+  +    EE+ V  +L       + +       
Sbjct: 2246 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGR 2305

Query: 258  ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286
             ++ +      E EE++ P  PR S    ++ GP
Sbjct: 2306 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 2339



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 48/214 (22%), Positives = 86/214 (40%), Gaps = 32/214 (14%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 2385 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2444

Query: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 2445 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 2489

Query: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257
            EV +DSL+ C  T S+     DS QP+  +    EE+ V  +L       + +       
Sbjct: 2490 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGR 2549

Query: 258  ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286
             ++ +      E EE++ P  PR S    ++ GP
Sbjct: 2550 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 2583



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 48/215 (22%), Positives = 86/215 (40%), Gaps = 32/215 (14%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 2873 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2932

Query: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 2933 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 2977

Query: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257
            EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 2978 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 3037

Query: 258  ENESD-----DEEEEEKGPVSPRTSVGSSEKGGPR 287
             ++ +      E EE++ P  PR S    ++ GP+
Sbjct: 3038 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPK 3072



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 32/214 (14%)

Query: 90  EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
           +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 675 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 734

Query: 141 GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197
              L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 735 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 779

Query: 198 EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257
           EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 780 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 839

Query: 258 ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286
            ++ +      E EE++ P  PR S    ++ GP
Sbjct: 840 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 873



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 32/214 (14%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 919  DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 978

Query: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 979  VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 1023

Query: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257
            EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 1024 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 1083

Query: 258  ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286
             ++ +      E EE++ P  PR S    ++ GP
Sbjct: 1084 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 1117



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 32/214 (14%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 2629 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 2688

Query: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 2689 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 2733

Query: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257
            EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 2734 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 2793

Query: 258  ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286
             ++ +      E EE++ P  PR S    ++ GP
Sbjct: 2794 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 2827



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 32/214 (14%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 3192 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 3251

Query: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197
               L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 3252 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 3296

Query: 198  EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257
            EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 3297 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 3356

Query: 258  ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286
             ++ +      E EE++ P  PR S    ++ GP
Sbjct: 3357 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 3390



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 1353 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGMAV-------- 1404

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 1405 ------DMDEIEKYQEVEEDQDPSCPRLS 1427



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 27/98 (27%), Positives = 41/98 (41%), Gaps = 14/98 (14%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  +V +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 3063 RELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQRVGLAV-------- 3114

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGP 286
                   + E E   E EE++ P  PR S    ++ GP
Sbjct: 3115 ------DMDEIEKYQEVEEDQDPSCPRLSRELLDEKGP 3146



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
           RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 865 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAV-------- 916

Query: 249 WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                  + E E   E EE++ P  PR S
Sbjct: 917 ------DMDEIEKYQEVEEDQDPSCPRLS 939



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 1109 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAV-------- 1160

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 1161 ------DMDEIEKYQEVEEDQDPSCPRLS 1183



 Score = 32.3 bits (72), Expect = 0.52
 Identities = 44/211 (20%), Positives = 83/211 (39%), Gaps = 26/211 (12%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
            +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 1163 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSA 1222

Query: 141  GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPREMQKAEEKEVP 200
               L+EQ   G  L    V ++  + + ++D+D               RE+ +    EV 
Sbjct: 1223 VYSLEEQYL-GLALD---VDRIKKDEEEEEDQDPPCPRLS--------RELLEVVAPEVL 1270

Query: 201  EDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENE 260
            +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +        ++
Sbjct: 1271 QDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSK 1330

Query: 261  SD-----DEEEEEKGPVSPRTSVGSSEKGGP 286
             +      E EE++ P  PR S    ++ GP
Sbjct: 1331 KERRRGRKEGEEDQNPPCPRLSRELLDEKGP 1361



 Score = 32.3 bits (72), Expect = 0.52
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 3/64 (4%)

Query: 180  EKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV 236
            E+ Q    PR    + + EE+EV +DSL+ C  T S      DS Q +R    +FEE  +
Sbjct: 3539 EEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHI 3598

Query: 237  DSTL 240
               L
Sbjct: 3599 SFAL 3602



 Score = 32.0 bits (71), Expect = 0.68
 Identities = 28/104 (26%), Positives = 45/104 (43%), Gaps = 17/104 (16%)

Query: 177 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 233
           +V ++ Q+++ PR   E+   +  EV +DS + C  T S      DS QP+R      E+
Sbjct: 606 QVKKEDQEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQ 665

Query: 234 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
            +V   +               + E E   E EE++ P  PR S
Sbjct: 666 QRVGLAI--------------DMDEIEKYQEVEEDQDPSCPRLS 695



 Score = 32.0 bits (71), Expect = 0.68
 Identities = 23/68 (33%), Positives = 32/68 (47%), Gaps = 3/68 (4%)

Query: 169  DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
            D DE  + +  E+ Q  S PR   E+   +E EV +DSL+ C  T S      D  QP+ 
Sbjct: 3434 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3493

Query: 226  KTKITFEE 233
                + EE
Sbjct: 3494 SAVYSLEE 3501



 Score = 31.6 bits (70), Expect = 0.89
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+  V   +        
Sbjct: 1599 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAV-------- 1650

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 1651 ------DMDEIEKYQEVEEDQDPSCPRLS 1673



 Score = 31.6 bits (70), Expect = 0.89
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+  V   +        
Sbjct: 1843 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAV-------- 1894

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 1895 ------DMDEIEKYQEVEEDQDPSCPRLS 1917



 Score = 31.6 bits (70), Expect = 0.89
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+  V   +        
Sbjct: 2087 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAV-------- 2138

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 2139 ------DMDEIEKYQEVEEDQDPSCPRLS 2161



 Score = 31.6 bits (70), Expect = 0.89
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+  V   +        
Sbjct: 2331 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAV-------- 2382

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 2383 ------DMDEIEKYQEVEEDQDPSCPRLS 2405



 Score = 31.6 bits (70), Expect = 0.89
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+  V   +        
Sbjct: 2575 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAV-------- 2626

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 2627 ------DMDEIEKYQEVEEDQDPSCPRLS 2649



 Score = 31.6 bits (70), Expect = 0.89
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+  V   +        
Sbjct: 2819 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAV-------- 2870

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 2871 ------DMDEIEKYQEVEEDQDPSCPRLS 2893



 Score = 31.6 bits (70), Expect = 0.89
 Identities = 26/89 (29%), Positives = 36/89 (40%), Gaps = 14/89 (15%)

Query: 189  REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
            RE+   +  EV +DSL+ C  T S      DS QP+R      E+  V   +        
Sbjct: 3382 RELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAV-------- 3433

Query: 249  WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                   + E E   E EE++ P  PR S
Sbjct: 3434 ------DMDEIEKYQEVEEDQDPSCPRLS 3456


>gi|14149997 neuroblastoma breakpoint family, member 3 [Homo
           sapiens]
          Length = 633

 Score =  448 bits (1152), Expect = e-126
 Identities = 228/287 (79%), Positives = 253/287 (88%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGP S EKAEMNILEIN+K RPQLAE KQQFR+LK+KC VTQ+A FLA +QN Y Y
Sbjct: 57  MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQVAYFLANRQNNYDY 116

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           E+CKDLIKSMLR+E    EEKLAE+L QAEELRQYKVLVHSQERELTQLREKL+EGRDAS
Sbjct: 117 EDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDAS 176

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
           RSLN+HLQALLTPDEPD SQG+DL+EQLAEGCRLAQHLVQKLSPEND+D+DEDV+VE AE
Sbjct: 177 RSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDVKVEEAE 236

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KVQ+  +PRE+QKAEEKEVPEDSLEECAITCSNSH P +SNQP+  T+ITFEED+VDSTL
Sbjct: 237 KVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVDSTL 296

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287
           I SSSH EW DAV IIPENESD E+EEEKGPVSPR    S E+  P+
Sbjct: 297 IDSSSHDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQ 343



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 27/75 (36%), Positives = 37/75 (49%), Gaps = 3/75 (4%)

Query: 169 DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
           D DE  + +  E+ QK   PR    + +AEE EV +DSL+ C  T S     + S Q +R
Sbjct: 533 DVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYR 592

Query: 226 KTKITFEEDKVDSTL 240
               +FEE  V   L
Sbjct: 593 SAFYSFEEQDVSLAL 607



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 29/104 (27%), Positives = 47/104 (45%), Gaps = 17/104 (16%)

Query: 177 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 233
           +V ++ Q+++SPR   E+   +E EV +DSL+    T        D  QP+R    + +E
Sbjct: 391 QVKKEDQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQE 450

Query: 234 DKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
             +   L               +   + D EEEE++GP  PR S
Sbjct: 451 QHLGLALD--------------LDRMKKDQEEEEDQGPPCPRLS 480


>gi|114158664 hypothetical protein LOC343505 [Homo sapiens]
          Length = 421

 Score =  424 bits (1091), Expect = e-119
 Identities = 216/280 (77%), Positives = 243/280 (86%), Gaps = 2/280 (0%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY 60
           MVVSAGP SSEKAEMNILEINEKLRPQLAE KQQFR++K+K  VTQ+AGFLA QQNKYKY
Sbjct: 21  MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGFLANQQNKYKY 80

Query: 61  EECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDAS 120
           EECKDLIKSMLR ELQFKEEKLAEQLKQAEELRQYKVLVHSQEREL QLREKLREGRDAS
Sbjct: 81  EECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDAS 140

Query: 121 RSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAE 180
            SLN+HLQALLTPD+ D SQGQD +EQLAEGCRLA+HLV KLSPEND D+DE+ + +  +
Sbjct: 141 HSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDENDKTKELD 200

Query: 181 KVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           KVQ+S +PRE QKAEEKEVPEDSLEECAIT SNSHGP DSN PH+  KIT EEDKV+S L
Sbjct: 201 KVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVNSIL 260

Query: 241 I--GSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTSV 278
           +    SS  EW+DA++I+ EN++DDEEEE K PV P+ ++
Sbjct: 261 VVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTL 300


>gi|7657017 hypothetical protein LOC25832 [Homo sapiens]
          Length = 921

 Score =  410 bits (1054), Expect = e-115
 Identities = 206/218 (94%), Positives = 210/218 (96%)

Query: 70  MLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQA 129
           MLRNE QFKEEKLAEQLKQAEELRQYKVLVH+QERELTQLREKLREGRDASRSLNEHLQA
Sbjct: 1   MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60

Query: 130 LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR 189
           LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSS+PR
Sbjct: 61  LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR 120

Query: 190 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 249
           EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW
Sbjct: 121 EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEW 180

Query: 250 EDAVHIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPR 287
           EDAVHIIPENESDDEEEEEKGPVSPR    S E+  P+
Sbjct: 181 EDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQ 218



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 34/112 (30%), Positives = 47/112 (41%), Gaps = 17/112 (15%)

Query: 169 DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
           D DE  + +  E+ Q  S PR   E+   +E EV +DSL  C  T S      D  QP+ 
Sbjct: 652 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYS 711

Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
               + EE  +   L               +   + D EEEE++GP  PR S
Sbjct: 712 SAVYSLEEQYLGLALD--------------VDRIKKDQEEEEDQGPPCPRLS 749



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 33/112 (29%), Positives = 48/112 (42%), Gaps = 17/112 (15%)

Query: 169 DDDEDVQVEVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHR 225
           D DE  + +  E+ Q  S PR   E+   +E EV ++SL+ C  T S      DS QP+R
Sbjct: 577 DMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYR 636

Query: 226 KTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                 E+ +V   +               + E E   E EE++ P  PR S
Sbjct: 637 SAFYILEQQRVGLAV--------------DMDEIEKYQEVEEDQDPSCPRLS 674



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 48/214 (22%), Positives = 85/214 (39%), Gaps = 32/214 (14%)

Query: 90  EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
           +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 335 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSA 394

Query: 141 GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197
              L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 395 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 439

Query: 198 EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIP 257
           EV +DSL+ C  T S+     DS QP+  +    EE  V  +L       + +       
Sbjct: 440 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGR 499

Query: 258 ENESD-----DEEEEEKGPVSPRTSVGSSEKGGP 286
            ++ +      E EE++ P  PR S    ++ GP
Sbjct: 500 RSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGP 533



 Score = 33.1 bits (74), Expect = 0.31
 Identities = 27/89 (30%), Positives = 40/89 (44%), Gaps = 14/89 (15%)

Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
           RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V     G + +++
Sbjct: 281 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRV-----GLAVNMD 335

Query: 249 WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                    E E   E EE++ P  PR S
Sbjct: 336 ---------EIEKYQEVEEDQDPSCPRLS 355



 Score = 32.3 bits (72), Expect = 0.52
 Identities = 26/89 (29%), Positives = 37/89 (41%), Gaps = 14/89 (15%)

Query: 189 REMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVE 248
           RE+   +  EV +DSL+ C  T S      DS QP+R      E+ +V   +        
Sbjct: 525 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGLAV-------- 576

Query: 249 WEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                  + E E   E EE++ P  PR S
Sbjct: 577 ------DMDEIEKYQEVEEDQDPSCPRLS 599



 Score = 32.0 bits (71), Expect = 0.68
 Identities = 39/163 (23%), Positives = 67/163 (41%), Gaps = 27/163 (16%)

Query: 90  EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPD---------EPDKSQ 140
           +E+ +Y+ +   Q+    +L  +L + ++     +   +   TP          +P  S 
Sbjct: 654 DEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSA 713

Query: 141 GQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR---EMQKAEEK 197
              L+EQ   G  L    ++K     D +++ED         Q    PR   E+ +  E 
Sbjct: 714 VYSLEEQYL-GLALDVDRIKK-----DQEEEED---------QGPPCPRLSRELLEVVEP 758

Query: 198 EVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 240
           EV +DSL+ C  T S+     DS QP+  +    EE  V  +L
Sbjct: 759 EVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSL 801



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 22/64 (34%), Positives = 31/64 (48%), Gaps = 3/64 (4%)

Query: 180 EKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV 236
           E+ Q    PR    + + EE EV +DSL+ C  T S      DS Q +R    +FEE+ +
Sbjct: 832 EEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEEEHI 891

Query: 237 DSTL 240
              L
Sbjct: 892 SFAL 895


>gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2
           [Homo sapiens]
          Length = 638

 Score =  368 bits (945), Expect = e-102
 Identities = 196/280 (70%), Positives = 228/280 (81%), Gaps = 6/280 (2%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGF-LAKQQNKYK 59
           MVVSA PLSSE+AEMNILEIN++LR QLAE  QQFR LKEK  +TQ   + LA Q  KYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 60  YEECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119
            EE KD+I S+LR+ELQ   EKLAE+L+QAEELRQYK LVHSQ +ELTQLREKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 120 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVE 177
           SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D+DED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 178 VAEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVD 237
             EKVQ+S +PRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPHR TKITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 238 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPR 275
           S L+  S H   E E+A++I PEN++D EEEE K PV PR
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR 279



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 19/124 (15%)

Query: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------NDDDEDVQVEVAEKVQKSSS- 187
           P +    ++ ++  +GC L   ++  L+P          + +D+ V + + +K++K    
Sbjct: 348 PLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEE 407

Query: 188 --------PR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV 236
                   PR   E+ + +E+EVPEDS+ E  +T S  H   D +QP+  T  + E+   
Sbjct: 408 IEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLA 467

Query: 237 DSTL 240
            S L
Sbjct: 468 CSAL 471



 Score = 36.2 bits (82), Expect = 0.036
 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 18/100 (18%)

Query: 181 KVQKSSSPREMQ---KAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVD 237
           K Q++ +PR  +   + ++ E+P++SL+ C +T S       S  P+  T  +FE+ +V 
Sbjct: 335 KGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQV- 393

Query: 238 STLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                         ++ ++ + + D EE E++ P  PR S
Sbjct: 394 --------------SLALVDKIKKDQEEIEDQSPPCPRLS 419


>gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1
           [Homo sapiens]
          Length = 667

 Score =  368 bits (945), Expect = e-102
 Identities = 196/280 (70%), Positives = 228/280 (81%), Gaps = 6/280 (2%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGF-LAKQQNKYK 59
           MVVSA PLSSE+AEMNILEIN++LR QLAE  QQFR LKEK  +TQ   + LA Q  KYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 60  YEECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119
            EE KD+I S+LR+ELQ   EKLAE+L+QAEELRQYK LVHSQ +ELTQLREKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 120 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVE 177
           SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D+DED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 178 VAEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVD 237
             EKVQ+S +PRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPHR TKITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 238 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPR 275
           S L+  S H   E E+A++I PEN++D EEEE K PV PR
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR 279



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 19/124 (15%)

Query: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------NDDDEDVQVEVAEKVQKSSS- 187
           P +    ++ ++  +GC L   ++  L+P          + +D+ V + + +K++K    
Sbjct: 377 PLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEE 436

Query: 188 --------PR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV 236
                   PR   E+ + +E+EVPEDS+ E  +T S  H   D +QP+  T  + E+   
Sbjct: 437 IEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLA 496

Query: 237 DSTL 240
            S L
Sbjct: 497 CSAL 500



 Score = 36.2 bits (82), Expect = 0.036
 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 18/100 (18%)

Query: 181 KVQKSSSPREMQ---KAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVD 237
           K Q++ +PR  +   + ++ E+P++SL+ C +T S       S  P+  T  +FE+ +V 
Sbjct: 364 KGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQV- 422

Query: 238 STLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                         ++ ++ + + D EE E++ P  PR S
Sbjct: 423 --------------SLALVDKIKKDQEEIEDQSPPCPRLS 448


>gi|221218991 neuroblastoma breakpoint family, member 4 [Homo
           sapiens]
          Length = 638

 Score =  368 bits (945), Expect = e-102
 Identities = 196/280 (70%), Positives = 228/280 (81%), Gaps = 6/280 (2%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGF-LAKQQNKYK 59
           MVVSA PLSSE+AEMNILEIN++LR QLAE  QQFR LKEK  +TQ   + LA Q  KYK
Sbjct: 1   MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60

Query: 60  YEECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119
            EE KD+I S+LR+ELQ   EKLAE+L+QAEELRQYK LVHSQ +ELTQLREKLREGRDA
Sbjct: 61  CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119

Query: 120 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVE 177
           SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D+DED   + E
Sbjct: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179

Query: 178 VAEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVD 237
             EKVQ+S +PRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPHR TKITF+E +VD
Sbjct: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239

Query: 238 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPR 275
           S L+  S H   E E+A++I PEN++D EEEE K PV PR
Sbjct: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR 279



 Score = 45.1 bits (105), Expect = 8e-05
 Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 19/124 (15%)

Query: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------NDDDEDVQVEVAEKVQKSSS- 187
           P +    ++ ++  +GC L   ++  L+P          + +D+ V + + +K++K    
Sbjct: 348 PLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEE 407

Query: 188 --------PR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV 236
                   PR   E+ + +E+EVPEDS+ E  +T S  H   D +QP+  T  + E+   
Sbjct: 408 IEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLA 467

Query: 237 DSTL 240
            S L
Sbjct: 468 CSAL 471



 Score = 36.2 bits (82), Expect = 0.036
 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 18/100 (18%)

Query: 181 KVQKSSSPREMQ---KAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVD 237
           K Q++ +PR  +   + ++ E+P++SL+ C +T S       S  P+  T  +FE+ +V 
Sbjct: 335 KGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQV- 393

Query: 238 STLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
                         ++ ++ + + D EE E++ P  PR S
Sbjct: 394 --------------SLALVDKIKKDQEEIEDQSPPCPRLS 419


>gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score =  117 bits (293), Expect = 1e-26
 Identities = 74/190 (38%), Positives = 108/190 (56%), Gaps = 9/190 (4%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGF-LAKQQNKYK 59
           M VSA      +AEM+ILE N+ LR +L + KQ F+ L EK   ++   + L     KYK
Sbjct: 1   MAVSATTCFGPRAEMSILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 60  YEECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119
            EECKDLI+S+L  E+QF+E +LAE  + A  LR +  L+ +Q  ELT LR+K++EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKIQEGRGV 120

Query: 120 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN-DDD 171
                +H+       + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN N   +
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 172 EDVQVEVAEK 181
           ED Q  +A +
Sbjct: 181 EDRQKPLAPR 190


>gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint family
           member 6-like protein [Homo sapiens]
          Length = 298

 Score =  114 bits (286), Expect = 8e-26
 Identities = 73/190 (38%), Positives = 107/190 (56%), Gaps = 9/190 (4%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGF-LAKQQNKYK 59
           M VSA      +AE++ILE N+ LR +L + KQ F+ L EK   ++   + L     KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 60  YEECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119
            EECKDLI+S+L  E+QF+E +LAE  + A  LR +  L+ +Q  ELT LR+K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 120 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN-DDD 171
                +H+       + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN N   +
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 172 EDVQVEVAEK 181
           ED Q  +A +
Sbjct: 181 EDRQKPLAPR 190


>gi|239741281 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 322

 Score =  114 bits (286), Expect = 8e-26
 Identities = 73/190 (38%), Positives = 107/190 (56%), Gaps = 9/190 (4%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGF-LAKQQNKYK 59
           M VSA      +AE++ILE N+ LR +L + KQ F+ L EK   ++   + L     KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 60  YEECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119
            EECKDLI+S+L  E+QF+E +LAE  + A  LR +  L+ +Q  ELT LR+K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 120 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN-DDD 171
                +H+       + LL   +    Q Q   EQ+ +G +L + LV+KL+ EN N   +
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180

Query: 172 EDVQVEVAEK 181
           ED Q  +A +
Sbjct: 181 EDRQKPLAPR 190


>gi|239752894 PREDICTED: Neuroblastoma breakpoint family member
           6-like protein [Homo sapiens]
          Length = 298

 Score =  112 bits (279), Expect = 5e-25
 Identities = 73/190 (38%), Positives = 105/190 (55%), Gaps = 9/190 (4%)

Query: 1   MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGF-LAKQQNKYK 59
           M VSA      +AE++ILE N+ LR +L + KQ F+ L EK   ++   + L     KYK
Sbjct: 1   MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60

Query: 60  YEECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119
            EECKDLI+S+L  E+QF+E +LAE  + A  LR +  L+ +Q  ELT LR+K +EGR  
Sbjct: 61  CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120

Query: 120 SRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN-DDD 171
                +H+       + LL        Q Q   EQ+ +G +L + LV+KL  EN N   +
Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTGIAYYQRQRFCEQMVQGSQLTEILVRKLVTENHNGKKN 180

Query: 172 EDVQVEVAEK 181
           ED Q  +A +
Sbjct: 181 EDRQKPLAPR 190


>gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo
            sapiens]
          Length = 2346

 Score = 82.0 bits (201), Expect = 6e-16
 Identities = 70/254 (27%), Positives = 120/254 (47%), Gaps = 22/254 (8%)

Query: 49   GFLAKQQNKYKYEECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQ 108
            G  AK+  +   +    L   + +N L   EEKLAE+L+ A    +Y  L+  Q REL+ 
Sbjct: 1431 GLQAKKDLESLIQRVSQLEAQLPKNGL---EEKLAEELRSASWPGKYDSLIQDQARELSY 1487

Query: 109  LREKLREGRDASRSLNEH-------LQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQK 161
            LR+K+REGR     +  H        + LL  ++ D   GQ  +EQLA+G +L + L  K
Sbjct: 1488 LRQKIREGRGICYLITRHAKDTVKSFEDLLRSNDIDYYLGQSFREQLAQGSQLTERLTSK 1547

Query: 162  LSPENDNDDDEDVQVE-VAEKVQKSSSPREMQKAEEK-EVPEDSLEECAITCSNSHGPYD 219
            LS ++   + +   +E +A ++      RE+Q+ E+  EV +  L+  ++T S+SH   D
Sbjct: 1548 LSTKDHKSEKDQAGLEPLALRLS-----RELQEKEKVIEVLQAKLDARSLTPSSSHALSD 1602

Query: 220  SNQPHRKTKITFEEDKV--DSTLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277
            S++    T    +E +   D  ++   +H E + A    P +            +S + S
Sbjct: 1603 SHRSPSSTSFLSDELEACSDMDIVSEYTHYEEKKA---SPSHSDSIHHSSHSAVLSSKPS 1659

Query: 278  VGSSEKGGPRGNRS 291
              S+ +G    + S
Sbjct: 1660 STSASQGAKAESNS 1673



 Score = 37.4 bits (85), Expect = 0.016
 Identities = 41/187 (21%), Positives = 80/187 (42%), Gaps = 34/187 (18%)

Query: 14  EMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSMLRN 73
           E NI  +N  L    + K+Q  +  +E          L  + N  K  E  +++   LR 
Sbjct: 433 EQNIQHLNHSL----SHKEQLLQEFRE---------LLQYRDNSDKTLEANEMLLEKLRQ 479

Query: 74  ELQFK--------EEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNE 125
            +  K        +EK +   ++ +ELRQ ++ V  ++ +L +LR+ L       +S+  
Sbjct: 480 RIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNEATMQSMES 539

Query: 126 HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKS 185
            L+A          +G ++ EQL+  C+  Q L +++  +      E  Q  + +++Q S
Sbjct: 540 LLRA----------KGLEV-EQLSTTCQNLQWLKEEMETKFSRWQKE--QESIIQQLQTS 586

Query: 186 SSPREMQ 192
              R  +
Sbjct: 587 LHDRNKE 593



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 52/211 (24%), Positives = 100/211 (47%), Gaps = 21/211 (9%)

Query: 18  LEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSM--LRNEL 75
           LEI +KL+  + +K++Q    K+     + A   ++QQ +  ++  ++L K++  L+ EL
Sbjct: 353 LEI-QKLQRVVRQKERQLADAKQCVQFVEAAAHESEQQKEASWKHNQELRKALQQLQEEL 411

Query: 76  QFKEEKL-AEQLKQAEELR----QYKVLVHS---QERELTQLREKL--REGRDASRSLNE 125
           Q K ++L A + ++  E+R      + L HS   +E+ L + RE L  R+  D +   NE
Sbjct: 412 QNKSQQLRAWEAEKYNEIRTQEQNIQHLNHSLSHKEQLLQEFRELLQYRDNSDKTLEANE 471

Query: 126 HLQALLTPDEPDKSQGQD--LQEQLAEGCRLAQHLVQ-KLSPENDNDDDEDVQVEVAEKV 182
            L   L     DK+   +  + E+ +      + L Q +L+    + D E ++  ++   
Sbjct: 472 MLLEKLRQRIHDKAVALERAIDEKFSALEEKEKELRQLRLAVRERDHDLERLRDVLSSNE 531

Query: 183 QKSSSPREMQKAEEKEVPEDSLEECAITCSN 213
               S   + +A+  EV     E+ + TC N
Sbjct: 532 ATMQSMESLLRAKGLEV-----EQLSTTCQN 557



 Score = 28.9 bits (63), Expect = 5.8
 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 3/80 (3%)

Query: 90   EELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 149
            E+ R+ +  +    RE +Q  E LRE   A  S   HLQ L    E  K + Q L E L 
Sbjct: 1909 EDNRRLQAQLSHVSREHSQETESLRE---ALLSSRSHLQELEKELEHQKVERQQLLEDLR 1965

Query: 150  EGCRLAQHLVQKLSPENDND 169
            E  +   H  ++     +ND
Sbjct: 1966 EKQQEVLHFREERLSLQEND 1985



 Score = 28.1 bits (61), Expect = 9.8
 Identities = 40/174 (22%), Positives = 75/174 (43%), Gaps = 28/174 (16%)

Query: 22   EKLRPQLAEKKQQFRSLKEKCFVTQLAGFL-AKQQNKYKYEECKDLIKSMLRNELQFKEE 80
            + LR QL++ KQ+++ L+EK  +++   F  A +  KY+     + +      ++Q   +
Sbjct: 1214 QHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQ 1273

Query: 81   KL-------AEQLKQAEELRQYKVLVHSQERELTQLR----EKLREGRD-ASRSLNEHLQ 128
             L       +E   + EE    +   H+  +E+  +     E+ R G   AS S  + L+
Sbjct: 1274 DLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLE 1333

Query: 129  ALLTPDEPDKSQG------------QDLQEQLAEGCRLAQHL---VQKLSPEND 167
              L   E  +  G            +DL+ QL    ++ Q+L   V+ LS  +D
Sbjct: 1334 NQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSD 1387


>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
           protein 6 [Homo sapiens]
          Length = 724

 Score = 50.4 bits (119), Expect = 2e-06
 Identities = 47/256 (18%), Positives = 111/256 (43%), Gaps = 11/256 (4%)

Query: 22  EKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSMLRNELQFKEE- 80
           EK+R Q   ++Q+ +  +++  + +    + +Q+ K   +E K   +  +R E + +E+ 
Sbjct: 464 EKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEEKRQEQE 523

Query: 81  ---KLAEQLKQAEELRQYKVLVHSQERELTQLREKL----REGRDASRSLNEHLQALLTP 133
              +  E++++ EE+ + K  +H QE ++ +  EK+     +  D    + E  + +   
Sbjct: 524 EMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ 583

Query: 134 DEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPREMQK 193
           +E  + Q + ++EQ  E  R  + + Q+   +    +++  + E   + Q+    R+ +K
Sbjct: 584 EEKIREQEEKIREQ-EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK 642

Query: 194 AEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV--DSTLIGSSSHVEWED 251
             E+E      EE            +     ++ K+  +E+K+      +       WE 
Sbjct: 643 IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQ 702

Query: 252 AVHIIPENESDDEEEE 267
            V +  + E   E +E
Sbjct: 703 EVRLRQQEEKMQEHQE 718



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 29/129 (22%), Positives = 65/129 (50%), Gaps = 19/129 (14%)

Query: 10  SEKAEMNILEINEKLRPQ---LAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDL 66
           +++ E  + E  EK+  Q   + E++++ R  +EK         + +Q+ K + +E K  
Sbjct: 608 TQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEK---------IREQEKKIREQEEKIR 658

Query: 67  IKSMLRNELQFKEEKLAEQ----LKQAEELRQYKVLVHSQERELTQLREKLREGRDASRS 122
            +  +  E   +EEK+ EQ     +Q E++++ +  +  QE ++ +   +LR+  +  + 
Sbjct: 659 EQEEMMQE---QEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQE 715

Query: 123 LNEHLQALL 131
             EHL+A +
Sbjct: 716 HQEHLEAAI 724


>gi|7657138 golgi integral membrane protein 4 [Homo sapiens]
          Length = 696

 Score = 50.1 bits (118), Expect = 2e-06
 Identities = 57/264 (21%), Positives = 113/264 (42%), Gaps = 32/264 (12%)

Query: 32  KQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSMLRNELQFKEEKLA-EQLKQAE 90
           ++Q R  KE+    + A  L        Y   K +IK     E Q ++++LA +Q+++A+
Sbjct: 366 EEQDREWKEQHEQREAANLLEGHARAEVYPSAKPMIKFQSPYEEQLEQQRLAVQQVEEAQ 425

Query: 91  ELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAE 150
           +LR+++  +H Q  +   LR++ ++ +  +R +    QA L   E  + Q Q+   Q A 
Sbjct: 426 QLREHQEALHQQRLQGHLLRQQEQQQQQVAREMALQRQAEL---EEGRPQHQEQLRQQAH 482

Query: 151 GCRLAQHLVQKLSP----------ENDNDDDEDVQVEVAEKVQ-KSSSPREMQKAEEKE- 198
              +   +VQ              E DN   ++ + +   + + +   PRE     E + 
Sbjct: 483 YDAMDNDIVQGAEDQGIQGEEGAYERDNQHQDEAEGDPGNRHEPREQGPREADPESEADR 542

Query: 199 --------------VPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSS 244
                           ED  EE A      + P D N+  +++    E  +V+  L+ + 
Sbjct: 543 AAVEDINPADDPNNQGEDEFEE-AEQVREENLP-DENEEQKQSNQKQENTEVEEHLVMAG 600

Query: 245 SHVEWEDAVHIIPENESDDEEEEE 268
           +  + ED V    + E+++E +E+
Sbjct: 601 NPDQQEDNVDEQYQEEAEEEVQED 624



 Score = 41.2 bits (95), Expect = 0.001
 Identities = 33/136 (24%), Positives = 54/136 (39%), Gaps = 27/136 (19%)

Query: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDD-DEDVQVEVAEKVQKSSSPREMQKA 194
           PD+++ Q    Q  E   + +HLV   +P+   D+ DE  Q E  E+VQ           
Sbjct: 574 PDENEEQKQSNQKQENTEVEEHLVMAGNPDQQEDNVDEQYQEEAEEEVQ----------- 622

Query: 195 EEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAVH 254
             +++ E+   E       ++G  D N   +      +E + D+   G   H E      
Sbjct: 623 --EDLTEEKKRELEHNAEETYGENDENTDDKNNDGEEQEVRDDNRPKGREEHYE------ 674

Query: 255 IIPENESDDEEEEEKG 270
                  ++EEEEE G
Sbjct: 675 -------EEEEEEEDG 683



 Score = 32.3 bits (72), Expect = 0.52
 Identities = 48/224 (21%), Positives = 92/224 (41%), Gaps = 38/224 (16%)

Query: 17  ILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGF----LAKQQNKYKYEECK---DLIKS 69
           + E   +L   L +++ + +  KE   V +L         +Q +  +Y        ++KS
Sbjct: 64  VYEHRSRLEKSLQKERLEHKKAKEDFLVYKLEAQETLNKGRQDSNSRYSALNVQHQMLKS 123

Query: 70  MLRNELQFKEEKLAEQ-LKQAEEL--------RQYKVLVHSQERELTQLREKLREGRDAS 120
               EL+ +   L E+  KQ E+         ++Y  L   +E+EL++L+E +   R+ +
Sbjct: 124 Q-HEELKKQHSDLEEEHRKQGEDFSRTFNDHKQKYLQLQQEKEQELSKLKETVYNLREEN 182

Query: 121 RSLNEHLQALLTPDEPDKSQGQDL---------------------QEQLAEGCRLAQHLV 159
           R L +  Q + T  +  K Q ++L                     Q Q+AE  +L   L 
Sbjct: 183 RQLRKAHQDIHTQLQDVKQQHKNLLSEHEQLVVTLEDHKSALAAAQTQVAEYKQLKDTLN 242

Query: 160 QKLSPENDNDDDEDVQVEVAEKVQKSSSPREMQKAEEKEVPEDS 203
           +  S    +  ++    +VA   Q  ++ RE    E +EV  ++
Sbjct: 243 RIPSLRKPDPAEQQNVTQVAHSPQGYNTAREKPTREVQEVSRNN 286


>gi|148746195 trichohyalin [Homo sapiens]
          Length = 1943

 Score = 49.7 bits (117), Expect = 3e-06
 Identities = 54/219 (24%), Positives = 98/219 (44%), Gaps = 31/219 (14%)

Query: 11   EKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSM 70
            +K E  + E  EK R Q  EKK +    +E+    +    L +++ K + +E +   +  
Sbjct: 968  QKEEQLLGEEPEKRRRQEREKKYR----EEEELQQEEEQLLREEREKRRRQEWERQYRK- 1022

Query: 71   LRNELQFKEEKLAE-------------QLKQAEELRQYKVLVHSQERELTQLREKLREGR 117
             ++ELQ +EE+L               Q ++ EEL+Q +  +  +ERE  + +E  R+ R
Sbjct: 1023 -KDELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYR 1081

Query: 118  DASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN--------- 168
                   E  Q  L  +EP+K + Q+ + Q  E   L Q   Q L  E +          
Sbjct: 1082 KEEELQQEEEQ--LLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQELERQ 1139

Query: 169  -DDDEDVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEE 206
              ++E+VQ E  + +++    R  Q+ E +   E+ L++
Sbjct: 1140 YREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQ 1178



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 50/215 (23%), Positives = 103/215 (47%), Gaps = 23/215 (10%)

Query: 11   EKAEMNILEINEKLRPQLAEKKQQFRS-----LKEKCFVTQLAGFLAKQQNKYKYEECKD 65
            ++ E  + E  EK R Q  E+++Q+R       KE+  + +      +Q+ + KY E ++
Sbjct: 938  QEEEQLLREEREKRRRQ--ERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEE 995

Query: 66   LIKS---MLRNELQFKEEKLAE-QLKQAEELRQYKVLVHSQERELTQLREKLREGRDASR 121
            L +    +LR E + +  +  E Q ++ +EL+Q +  +  +ERE  +L+E+ R+ R+   
Sbjct: 996  LQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYREEEE 1055

Query: 122  SLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN----------DDD 171
               E  Q  L  +E +  + Q+L+ Q  +   L Q   Q L  E +            ++
Sbjct: 1056 LQQEEEQ--LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREE 1113

Query: 172  EDVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEE 206
            E++Q E  + +++    R  Q+ E +   E+ +++
Sbjct: 1114 EELQQEEEQLLREEREKRRRQELERQYREEEEVQQ 1148



 Score = 44.3 bits (103), Expect = 1e-04
 Identities = 44/194 (22%), Positives = 91/194 (46%), Gaps = 24/194 (12%)

Query: 22  EKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSMLRNELQFK--E 79
           E+ R Q   ++QQ R  +E+           +++ + K +E ++ ++  LR+E Q +  +
Sbjct: 494 EERREQQERREQQLRREQEE-----------RREQRLKRQEEEERLQQRLRSEQQLRREQ 542

Query: 80  EKLAEQL------KQAEELRQYKVLVHSQERELTQL--REKLREGRDASRSLNEHLQALL 131
           E+  EQL      K+ E+ R+ + L   QE    QL  RE+ R  +   R   E L+  L
Sbjct: 543 EERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRL 602

Query: 132 TPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPREM 191
             +E ++ + ++ +EQ  +     +   Q+L    + ++    Q+    + Q+    + +
Sbjct: 603 KREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEERRQQQL---RREQQERREQRL 659

Query: 192 QKAEEKEVPEDSLE 205
           ++ EE+E  E  L+
Sbjct: 660 KREEEEERLEQRLK 673



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 52/214 (24%), Positives = 95/214 (44%), Gaps = 22/214 (10%)

Query: 11   EKAEMNILEINEKLRPQLAEKKQQFRS-----LKEKCFVTQLAGFLAKQQNKYKYEECKD 65
            ++ E  + E  EK R Q  E ++Q+R       +E+  + +      +Q+ + +Y E ++
Sbjct: 1118 QEEEQLLREEREKRRRQ--ELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEE 1175

Query: 66   LIKS---MLRNELQFKEEKLAEQLKQAEEL-RQYKVLVHSQERELTQLR-----EKLREG 116
            L +    +LR E + + ++   Q ++ EEL RQ +   +  E + + L+     EK    
Sbjct: 1176 LQQEEEQLLREEQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAV 1235

Query: 117  RD----ASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDE 172
            RD         NE  + L      D+   QDLQ  L E     +   ++   + D    E
Sbjct: 1236 RDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPE 1295

Query: 173  DVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEE 206
            + Q+E  E  QK +  R+ +  EEK++  +  EE
Sbjct: 1296 EEQLEREE--QKEAKRRDRKSQEEKQLLREEREE 1327



 Score = 39.7 bits (91), Expect = 0.003
 Identities = 49/199 (24%), Positives = 92/199 (46%), Gaps = 27/199 (13%)

Query: 21   NEKLRPQLAEKKQQFR-SLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSMLRNELQFKE 79
            ++K R QL E++++ R +L  K     L   L K+Q   + EE     + + R E + + 
Sbjct: 871  DQKWRWQLEEERKRRRHTLYAK---PALQEQLRKEQQLLQEEE-----EELQREEREKRR 922

Query: 80   EKLAE-QLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDK 138
             +  E Q ++ E+L+Q +  +  +ERE  + +E+ R+ R   +   +  Q  L  +EP+K
Sbjct: 923  RQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQ--LLGEEPEK 980

Query: 139  SQGQDLQEQLAEGCRLAQHLVQKLSPE---------------NDNDDDEDVQVEVAEKVQ 183
             + Q+ +++  E   L Q   Q L  E                D    E+ Q+   E+ +
Sbjct: 981  RRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREK 1040

Query: 184  KSSSPREMQKAEEKEVPED 202
            +    RE Q  EE+E+ ++
Sbjct: 1041 RRLQERERQYREEEELQQE 1059



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 54/234 (23%), Positives = 101/234 (43%), Gaps = 44/234 (18%)

Query: 8    LSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGF-------LAKQQNKYKY 60
            L  ++ +   LE   +LR Q  E++QQ R  +++ F  +           L +Q+   K+
Sbjct: 1636 LHRQERDRKFLEEEPQLRRQ--EREQQLRHDRDRKFREEEQLLQEGEEQQLRRQERDRKF 1693

Query: 61   EECKDLI------KSMLRNELQFKEEKLAEQLKQAEELRQ-------------YKVLVHS 101
             E +  +      +  L+ E Q + ++L  + ++ E+LRQ              K+L   
Sbjct: 1694 REEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEE 1753

Query: 102  Q---ERELTQLR--EKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQ 156
            Q   ERE  QLR  E+ R+ R+  +   E  +  L   E D+   +  +EQL +     +
Sbjct: 1754 QLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFRE--EEQLRQ-----E 1806

Query: 157  HLVQKLSPENDND----DDEDVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEE 206
               Q+L P+  +     ++E +Q+E  E+  +    R+ +  E+    E S  E
Sbjct: 1807 REEQQLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRRE 1860



 Score = 38.9 bits (89), Expect = 0.006
 Identities = 39/196 (19%), Positives = 85/196 (43%), Gaps = 9/196 (4%)

Query: 8   LSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLI 67
           L  E+ E  +    E+ R QL +++++ R  + K    +      K++   + E+ +   
Sbjct: 558 LEQERREQRLKREQEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERRE 617

Query: 68  KSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHL 127
           + + R E + +  +   + ++ EE RQ ++    QER   +L+ +  E R   R   EH 
Sbjct: 618 QRLKREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREH- 676

Query: 128 QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSS 187
                  E ++ + +  +E+  +     +  + K   + +++ D   Q +V  + +K   
Sbjct: 677 -------EEERREQELAEEEQEQARERIKSRIPKWQWQLESEADAR-QSKVYSRPRKQEG 728

Query: 188 PREMQKAEEKEVPEDS 203
            R  Q+ EEK    +S
Sbjct: 729 QRRRQEQEEKRRRRES 744



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 42/189 (22%), Positives = 88/189 (46%), Gaps = 21/189 (11%)

Query: 11  EKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSM 70
           ++ ++   E+ E  R    EK+QQ R  +++ F  +       ++ +++  E      ++
Sbjct: 206 DEEQLRRRELLELRRKGREEKQQQRRERQDRVFQEE-------EEKEWRKRE------TV 252

Query: 71  LRNELQFKEEKLAEQLKQAE-ELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQA 129
           LR E    EEKL E+  Q + EL++ +  +   ER+  +LR + +E     + L    Q 
Sbjct: 253 LRKE----EEKLQEEEPQRQRELQEEEEQLRKLERQ--ELRRERQEEEQQQQRLRREQQL 306

Query: 130 LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR 189
               +E  + Q ++ +EQ     +  +   Q+L  E +   ++ ++ E  E+ ++    R
Sbjct: 307 RRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRR 366

Query: 190 EMQKAEEKE 198
           E Q+ E +E
Sbjct: 367 E-QEEERRE 374



 Score = 37.0 bits (84), Expect = 0.021
 Identities = 47/226 (20%), Positives = 91/226 (40%), Gaps = 50/226 (22%)

Query: 53   KQQNKYKYEECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREK 112
            K++ + +  +C++        ELQ +EE+L                   +ERE  + +E 
Sbjct: 1100 KRRRQERERQCRE------EEELQQEEEQLLR-----------------EEREKRRRQEL 1136

Query: 113  LREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDN---- 168
             R+ R+      E  Q  L  +EP+K + Q+L+ Q  E   L Q   Q L  E +     
Sbjct: 1137 ERQYREEEEVQQEEEQ--LLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQE 1194

Query: 169  -----DDDEDVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQP 223
                  ++E++Q +  ++  +    R   K + +   E+++ +  + C         N+ 
Sbjct: 1195 RERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGR-----ENEQ 1249

Query: 224  HRKTKITFEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK 269
             R+ +        DS L    S    +D  H++ E +  D E+E +
Sbjct: 1250 FRQLE--------DSQLRDRQSQ---QDLQHLLGEQQERDREQERR 1284



 Score = 35.4 bits (80), Expect = 0.061
 Identities = 44/193 (22%), Positives = 78/193 (40%), Gaps = 30/193 (15%)

Query: 8   LSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLI 67
           L  E+ ++  LE  E  R +  E++QQ R  +E             QQ + K EE     
Sbjct: 271 LQEEEEQLRKLERQELRRERQEEEQQQQRLRRE-------------QQLRRKQEE----- 312

Query: 68  KSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHL 127
               R E Q +  +  E+ +Q EE R+ ++    +ER   QLR +  E R   +   E  
Sbjct: 313 ---ERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ- 368

Query: 128 QALLTPDEPDKSQGQDLQEQL--AEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKS 185
                 +E  + Q    ++QL   +  R  Q L ++     +     + Q+   +++++ 
Sbjct: 369 ------EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 422

Query: 186 SSPREMQKAEEKE 198
              R  Q+ E  E
Sbjct: 423 QQLRREQEEERHE 435



 Score = 34.3 bits (77), Expect = 0.14
 Identities = 46/191 (24%), Positives = 83/191 (43%), Gaps = 16/191 (8%)

Query: 11   EKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSM 70
            ++ E   L   E+ R  L E++Q  R  +++ F  Q    L  Q+ + K+ E +  +   
Sbjct: 1471 QEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQE---LRSQEPERKFLEEEQQLHRQ 1527

Query: 71   LRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREK---LREGRDASRSLNEHL 127
             R     +EE+   + ++ ++ RQ +     +E +L Q RE+    R+ RD    L E  
Sbjct: 1528 QRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEE-- 1585

Query: 128  QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQ-VEVAEKVQKSS 186
            Q +   ++  K    + Q +  EG        Q+L  E D    ED Q ++  E+ Q   
Sbjct: 1586 QKVRRQEQERKFMEDEQQLRRQEG-------QQQLRQERDRKFREDEQLLQEREEQQLHR 1638

Query: 187  SPREMQKAEEK 197
              R+ +  EE+
Sbjct: 1639 QERDRKFLEEE 1649



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 35/189 (18%), Positives = 83/189 (43%), Gaps = 8/189 (4%)

Query: 11  EKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSM 70
           E+ E  +    E+ R +   +++Q    +E+    +    L ++Q   + ++ +   +  
Sbjct: 345 ERREQQLRREQEEERREQQLRREQEEERREQQLRREQQ--LRREQQLRREQQLRR--EQQ 400

Query: 71  LRNELQFKEEKLAEQLKQAEELRQYKVLVHSQEREL-TQLREKLREGRDASRSLNEHLQA 129
           LR E Q + E   +QL++ ++LR+ + L   QE E   Q  E+ R  +   R   E    
Sbjct: 401 LRREQQLRRE---QQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDW 457

Query: 130 LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPR 189
           L   +E ++ + +  ++QL       +        E +  + ++ + +   + Q+    +
Sbjct: 458 LKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQ 517

Query: 190 EMQKAEEKE 198
            +++ EE+E
Sbjct: 518 RLKRQEEEE 526



 Score = 30.8 bits (68), Expect = 1.5
 Identities = 35/181 (19%), Positives = 82/181 (45%), Gaps = 9/181 (4%)

Query: 18   LEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSMLRNELQF 77
            L   E+ R  L E+++  R  +E+ F+        K++ + + +E +  ++     + + 
Sbjct: 1367 LRHQEQGRKFLEEEQRLRRQERERKFL--------KEEQQLRCQEREQQLRQDRDRKFRE 1418

Query: 78   KEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPD 137
            +E++L+ Q ++  + R+ +  V  QERE   L E+ +  ++  R   E  Q L   +E  
Sbjct: 1419 EEQQLSRQ-ERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQ 1477

Query: 138  KSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPREMQKAEEK 197
              + +  ++ L E  +L +    +   E +    E  +  + E+ Q     R+ +  +E+
Sbjct: 1478 LHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFLQEE 1537

Query: 198  E 198
            +
Sbjct: 1538 Q 1538



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 36/151 (23%), Positives = 69/151 (45%), Gaps = 12/151 (7%)

Query: 53  KQQNKYKYEECKDLIKSMLRNELQFKEEKLAEQLKQAEELR-----QYKVLVHSQE-REL 106
           KQ+ + + +E ++  +    +ELQ++EE+ A + +Q EE R     Q++    S+  R+ 
Sbjct: 725 KQEGQRRRQEQEEK-RRRRESELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQR 783

Query: 107 TQLREKLREGRDASRSLNEHLQ--ALLTPDEPDKSQGQDLQEQLAEGCRL--AQHLVQKL 162
              R  LRE R+      E  Q      P+E +K Q +  + +  +  +    +  +Q+ 
Sbjct: 784 LSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRR 843

Query: 163 SPENDNDDDEDVQVEVAEKVQKSSSPREMQK 193
                  ++ED   E  E+ ++S   R  QK
Sbjct: 844 ERAQQLQEEEDGLQEDQER-RRSQEQRRDQK 873



 Score = 29.6 bits (65), Expect = 3.4
 Identities = 39/194 (20%), Positives = 84/194 (43%), Gaps = 15/194 (7%)

Query: 12   KAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSML 71
            + E   L   E+ R    E++Q  R  +E+ F+ +      ++  K++ EE   L++   
Sbjct: 1417 REEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEE--QLLQERE 1474

Query: 72   RNEL--QFKEEKLAE---QLKQAE---ELRQYKVLVHSQERELTQLREKLREGRDASRSL 123
              +L  Q ++ K  E   QL++ E   + R+ ++     ER+  +  ++L   +   + L
Sbjct: 1475 EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFL 1534

Query: 124  NEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQ 183
             E  Q  L   E  + + QD   +  E  +L Q   ++     + D    ++    +KV+
Sbjct: 1535 QEEQQ--LRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLE---EQKVR 1589

Query: 184  KSSSPREMQKAEEK 197
            +    R+  + E++
Sbjct: 1590 RQEQERKFMEDEQQ 1603



 Score = 28.5 bits (62), Expect = 7.5
 Identities = 29/154 (18%), Positives = 64/154 (41%), Gaps = 8/154 (5%)

Query: 53   KQQNKYKYEECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREK 112
            +Q+   K+ E + L        LQ +EE+   + ++  + R+ ++    Q R+  +  ++
Sbjct: 1331 RQETDRKFREEEQL--------LQEREEQPLRRQERDRKFREEELRHQEQGRKFLEEEQR 1382

Query: 113  LREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDE 172
            LR      + L E  Q      E    Q +D + +  E     Q   +K   E      +
Sbjct: 1383 LRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ 1442

Query: 173  DVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEE 206
            + + +  E+ Q+    R  +  EE+++ ++  E+
Sbjct: 1443 ERERKFLEEEQQLRQERHRKFREEEQLLQEREEQ 1476


>gi|21735548 centrosomal protein 2 [Homo sapiens]
          Length = 2442

 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 54/193 (27%), Positives = 89/193 (46%), Gaps = 22/193 (11%)

Query: 11   EKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSM 70
            E  E   +E+  +L+ Q  E +      +E+   TQ    L + Q + + E       S+
Sbjct: 878  ESLEREKMELEMRLKEQQTEMEAIQAQREEER--TQAESALCQMQLETEKERV-----SL 930

Query: 71   LRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELT-----QLREKLREGRDASRSLNE 125
            L   LQ ++E LA+  +Q E LRQ   +   +E+E T     QL+E  RE ++A+R   +
Sbjct: 931  LETLLQTQKE-LADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQRELKEAARQHRD 989

Query: 126  HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKS 185
             L AL            DLQ+Q+ +   L   LV +      +D    V+ EV EK++++
Sbjct: 990  DLAALQEESSSLLQDKMDLQKQVED---LKSQLVAQ------DDSQRLVEQEVQEKLRET 1040

Query: 186  SSPREMQKAEEKE 198
                 +QK  E+E
Sbjct: 1041 QEYNRIQKELERE 1053



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 57/217 (26%), Positives = 99/217 (45%), Gaps = 34/217 (15%)

Query: 8    LSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQL-----AGFL------AKQQN 56
            L +EK  +++LE   + + +LA+  QQ   L++   V +L      G L      A+++ 
Sbjct: 921  LETEKERVSLLETLLQTQKELADASQQLERLRQDMKVQKLKEQETTGILQTQLQEAQREL 980

Query: 57   KYKYEECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQ-LREKLRE 115
            K    + +D + ++        ++K+  Q KQ E+L+   V     +R + Q ++EKLRE
Sbjct: 981  KEAARQHRDDLAALQEESSSLLQDKMDLQ-KQVEDLKSQLVAQDDSQRLVEQEVQEKLRE 1039

Query: 116  GRDASR--------------SLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQK 161
             ++ +R              SL E  Q LL   E D  + Q+L   L +  + AQ   ++
Sbjct: 1040 TQEYNRIQKELEREKASLTLSLMEKEQRLLVLQEADSIRQQEL-SALRQDMQEAQGEQKE 1098

Query: 162  LSPENDNDDDEDVQVEVAEKVQKSSSPREMQKAEEKE 198
            LS +      E ++ EV EK +     +E Q  EE E
Sbjct: 1099 LSAQM-----ELLRQEVKEK-EADFLAQEAQLLEELE 1129



 Score = 41.6 bits (96), Expect = 9e-04
 Identities = 57/279 (20%), Positives = 112/279 (40%), Gaps = 60/279 (21%)

Query: 8    LSSEKAEMNILEINEK-LRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDL 66
            L ++ ++++ LE +   L  +L E+ Q+ +S +E     Q+     ++++  +  E +D 
Sbjct: 1604 LQAQSSQIHDLESHSTVLARELQERDQEVKSQRE-----QIEELQRQKEHLTQDLERRDQ 1658

Query: 67   IKSMLRNELQFKEEKLAEQLKQAEE-LRQYKVLVHSQERELTQLREKLREGRD------- 118
               + +  +Q  E++   Q K  EE L Q K+ +  + RELT  R+ ++E  +       
Sbjct: 1659 ELMLQKERIQVLEDQRTRQTKILEEDLEQIKLSLRERGRELTTQRQLMQERAEEGKGPSK 1718

Query: 119  ASRSLNEHLQALLTPDEPD--------------------KSQG----------------- 141
            A R   EH++ +L   E +                    + QG                 
Sbjct: 1719 AQRGSLEHMKLILRDKEKEVECQQEHIHELQELKDQLEQQLQGLHRKVGETSLLLSQREQ 1778

Query: 142  ------QDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPREMQKAE 195
                  Q LQE   +G    Q L  +L          D ++E  ++ Q+ +  +E +  E
Sbjct: 1779 EIVVLQQQLQEAREQGELKEQSLQSQLDEAQRALAQRDQELEALQQEQQQAQGQEERVKE 1838

Query: 196  EKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEED 234
            + +  + +LE+  +T    HG     Q H++     EE+
Sbjct: 1839 KADALQGALEQAHMTLKERHGEL---QDHKEQARRLEEE 1874



 Score = 39.3 bits (90), Expect = 0.004
 Identities = 58/209 (27%), Positives = 88/209 (42%), Gaps = 49/209 (23%)

Query: 17   ILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSML----- 71
            + ++ E+L    AEK Q    L++     QL+     Q+ K K+E  ++ ++S L     
Sbjct: 1266 VQKLEERLTDTEAEKSQVHTELQD--LQRQLS---QNQEEKSKWEGKQNSLESELMELHE 1320

Query: 72   ----------RNELQFKEEKLAEQLKQA---------EELRQYKVLVHSQERELTQLREK 112
                      R ELQ  E +   +L QA         E L+   V   +Q      L E 
Sbjct: 1321 TMASLQSRLRRAELQRMEAQGERELLQAAKENLTAQVEHLQAAVVEARAQASAAGILEED 1380

Query: 113  LREGRDASRSLNEHL-------QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPE 165
            LR  R A +  NE +       QAL    E   +QG+ LQE LA    L Q L ++    
Sbjct: 1381 LRTARSALKLKNEEVESERERAQALQEQGELKVAQGKALQENLA---LLTQTLAER---- 1433

Query: 166  NDNDDDEDVQVEVAEKVQKSSSPREMQKA 194
                 +E+V+  +  ++Q+    REMQKA
Sbjct: 1434 -----EEEVET-LRGQIQELEKQREMQKA 1456



 Score = 38.1 bits (87), Expect = 0.009
 Identities = 54/232 (23%), Positives = 106/232 (45%), Gaps = 33/232 (14%)

Query: 14   EMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSMLRN 73
            E  +LE+ EK    +  ++ Q + LK++  VT     L  ++N +K E  + LIK +   
Sbjct: 1525 EHQLLEL-EKKDQMIESQRGQVQDLKKQ-LVTLECLALELEENHHKMECQQKLIKEL--- 1579

Query: 74   ELQFKEEKLA------EQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHL 127
            E Q + +++A      +  ++++EL+     +H  E   T L  +L+E     +S  E +
Sbjct: 1580 EGQRETQRVALTHLTLDLEERSQELQAQSSQIHDLESHSTVLARELQERDQEVKSQREQI 1639

Query: 128  QAL------LTPDEPDKSQGQDLQE---QLAEGCRLAQHLVQKLSPENDNDDDEDVQVEV 178
            + L      LT D   + Q   LQ+   Q+ E  R  Q  + +       +D E +++ +
Sbjct: 1640 EELQRQKEHLTQDLERRDQELMLQKERIQVLEDQRTRQTKILE-------EDLEQIKLSL 1692

Query: 179  AEKVQKSSSPREM--QKAEEKEVP----EDSLEECAITCSNSHGPYDSNQPH 224
             E+ ++ ++ R++  ++AEE + P      SLE   +   +     +  Q H
Sbjct: 1693 RERGRELTTQRQLMQERAEEGKGPSKAQRGSLEHMKLILRDKEKEVECQQEH 1744



 Score = 36.6 bits (83), Expect = 0.028
 Identities = 38/133 (28%), Positives = 63/133 (47%), Gaps = 14/133 (10%)

Query: 24   LRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYE-ECKDLIKSMLRNELQFKEEKL 82
            L   LAE++++  +L+ +         L KQ+   K   E   L       E+  ++E++
Sbjct: 1426 LTQTLAEREEEVETLRGQIQE------LEKQREMQKAALELLSLDLKKRNQEVDLQQEQI 1479

Query: 83   AEQLKQAEELRQYKVLVHSQERELTQLREKLRE---GRDASRSLNEH-LQALLTPD---E 135
             E  K    L    + V  +E++LT  RE++RE    R+  R++ EH L  L   D   E
Sbjct: 1480 QELEKCRSVLEHLPMAVQEREQKLTVQREQIRELEKDRETQRNVLEHQLLELEKKDQMIE 1539

Query: 136  PDKSQGQDLQEQL 148
              + Q QDL++QL
Sbjct: 1540 SQRGQVQDLKKQL 1552



 Score = 30.4 bits (67), Expect = 2.0
 Identities = 35/134 (26%), Positives = 53/134 (39%), Gaps = 7/134 (5%)

Query: 69  SMLRNELQFKEEKLAEQLKQAEELRQYKVL-VHSQERELTQLREKLREG---RDASRSLN 124
           S L   L   +  L +QL Q EE  Q     + + E+    L+  L E    R+A    N
Sbjct: 602 SALNEALALDKVGLNQQLLQLEEENQSVCSRMEAAEQARNALQVDLAEAEKRREALWEKN 661

Query: 125 EHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQK 184
            HL+A L   E     G +LQ  L +     + + +KLS      +    Q+E   +  K
Sbjct: 662 THLEAQLQKAE---EAGAELQADLRDIQEEKEEIQKKLSESRHQQEAATTQLEQLHQEAK 718

Query: 185 SSSPREMQKAEEKE 198
                  +  +EKE
Sbjct: 719 RQEEVLARAVQEKE 732



 Score = 28.5 bits (62), Expect = 7.5
 Identities = 33/196 (16%), Positives = 79/196 (40%), Gaps = 15/196 (7%)

Query: 11   EKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSM 70
            E+A M + E + +L+    + K+Q R L+E+  V              + +  ++++  +
Sbjct: 1848 EQAHMTLKERHGELQ----DHKEQARRLEEELAV-----------EGRRVQALEEVLGDL 1892

Query: 71   LRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQAL 130
                 + ++  LA Q + AE+ ++++V   + +    Q +  L+E      +L    Q+ 
Sbjct: 1893 RAESREQEKALLALQQQCAEQAQEHEVETRALQDSWLQAQAVLKERDQELEALRAESQSS 1952

Query: 131  LTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPRE 190
               +E  +++ + LQE L +     Q   Q L  + +     +      +    +     
Sbjct: 1953 RHQEEAARARAEALQEALGKAHAALQGKEQHLLEQAELSRSLEASTATLQASLDACQAHS 2012

Query: 191  MQKAEEKEVPEDSLEE 206
             Q  E   + E  +++
Sbjct: 2013 RQLEEALRIQEGEIQD 2028


>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 523

 Score = 48.1 bits (113), Expect = 9e-06
 Identities = 46/203 (22%), Positives = 100/203 (49%), Gaps = 18/203 (8%)

Query: 20  INEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEE--CKDLIKSMLRNE--L 75
           +N +   +L E++++ R  +E+  + +    L +Q+ + + +E   ++  + +   E  L
Sbjct: 193 LNRRQEERLREQEERLREQEER--LREQEERLCEQEERLREQEERLREQEERLCEQEERL 250

Query: 76  QFKEEKLAEQ----LKQAEELRQYKVLVHSQERELTQLREKLREGR----DASRSLNEHL 127
           +  EE+L EQ     +Q E LR+ +  +H QE  L +  E+LRE      +    L E  
Sbjct: 251 REHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQE 310

Query: 128 QALLTPDEPDKSQGQDL--QEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVEVAEKVQ 183
           + L   +E  + Q + L  QE+L    RL + + + L  E   ++ E +  +  + E+V+
Sbjct: 311 ERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKLLEQERRQEEQERLLERERLLEEVE 370

Query: 184 KSSSPREMQKAEEKEVPEDSLEE 206
           +      +++ +E+   +++L+E
Sbjct: 371 ELLEQERLRQQDERLWQQETLQE 393



 Score = 33.5 bits (75), Expect = 0.23
 Identities = 27/97 (27%), Positives = 44/97 (45%), Gaps = 7/97 (7%)

Query: 55  QNKYKYEECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLR 114
           Q + +  +   L+       L+ +EE+L EQ    E LR+ +  +  QE  L +  E+LR
Sbjct: 181 QAEVENNQMLSLLNRRQEERLREQEERLREQ---EERLREQEERLCEQEERLREQEERLR 237

Query: 115 EGR----DASRSLNEHLQALLTPDEPDKSQGQDLQEQ 147
           E      +    L EH + L   +E    Q + L+EQ
Sbjct: 238 EQEERLCEQEERLREHEERLCEQEERLCEQEERLREQ 274



 Score = 32.3 bits (72), Expect = 0.52
 Identities = 32/138 (23%), Positives = 62/138 (44%), Gaps = 7/138 (5%)

Query: 73  NELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLT 132
           N L+ + E +  QL+   E  Q   L++ ++ E  +LRE+    R+    L E  + L  
Sbjct: 167 NHLRKELESVGRQLQAEVENNQMLSLLNRRQEE--RLREQEERLREQEERLREQEERLCE 224

Query: 133 PDEPDKSQGQDLQEQLAEGC----RLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSP 188
            +E  + Q + L+EQ    C    RL +H  ++L  + +   +++ ++   E+       
Sbjct: 225 QEERLREQEERLREQEERLCEQEERLREH-EERLCEQEERLCEQEERLREQEERLHEQEE 283

Query: 189 REMQKAEEKEVPEDSLEE 206
           R  ++ E     E+ L E
Sbjct: 284 RLCEQEERLREQEERLCE 301


>gi|84043963 eukaryotic translation initiation factor 5B [Homo
           sapiens]
          Length = 1220

 Score = 47.8 bits (112), Expect = 1e-05
 Identities = 62/276 (22%), Positives = 121/276 (43%), Gaps = 39/276 (14%)

Query: 22  EKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAK---QQNKYKYEECKDLIKSMLRNELQFK 78
           +K + +  EK+++ +    K  V  +   LAK   ++ + K EE ++ IK +   E + K
Sbjct: 319 KKKKGEKEEKEKEKKKGPSKATVKAMQEALAKLKEEEERQKREE-EERIKRLEELEAKRK 377

Query: 79  EEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQA--LLTPDEP 136
           EE+  EQ K+  + ++ K      ++E   L +  RE R  + +  + LQA  +  P + 
Sbjct: 378 EEERLEQEKRERKKQKEKERKERLKKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKD 437

Query: 137 DKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDE-DVQVEVAEK--VQKSSSPREMQK 193
              + + + E      +  + + Q+L  +  ++  E    VEV E+   +K  +P  ++ 
Sbjct: 438 SLPKKRPIYED-----KKRKKIPQQLESKEVSESMELCAAVEVMEQGVPEKEETPPPVEP 492

Query: 194 AEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHVEWEDAV 253
            EE++  +  L++     S+                  E +KV+    G+  H+E ++  
Sbjct: 493 EEEEDTEDAGLDDWEAMASDE-----------------ETEKVE----GNKVHIEVKEN- 530

Query: 254 HIIPENESDDEEEEEKGPVSPRTSVGSSEKGGPRGN 289
              PE E ++EEEEE+   S        E  G  G+
Sbjct: 531 ---PEEEEEEEEEEEEDEESEEEEEEEGESEGSEGD 563



 Score = 46.6 bits (109), Expect = 3e-05
 Identities = 61/296 (20%), Positives = 116/296 (39%), Gaps = 31/296 (10%)

Query: 7   PLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDL 66
           P S EKAE      ++    +  + K++ +  KE+            ++ + K    K  
Sbjct: 293 PASEEKAETPTAAEDDNEGDKKKKDKKKKKGEKEE------------KEKEKKKGPSKAT 340

Query: 67  IKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEH 126
           +K+M     + KEE+  ++ ++ E +++ + L   ++ E    +EK    +   +   E 
Sbjct: 341 VKAMQEALAKLKEEEERQKREEEERIKRLEELEAKRKEEERLEQEKRERKKQKEKERKER 400

Query: 127 LQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSS 186
           L          K +G+ L +   E    A+  ++ L  +      +D   +     +   
Sbjct: 401 L----------KKEGKLLTKSQREARARAEATLKLLQAQGVEVPSKDSLPKKRPIYEDKK 450

Query: 187 SPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL-----I 241
             +  Q+ E KEV E S+E CA       G  +  +     +   EED  D+ L     +
Sbjct: 451 RKKIPQQLESKEVSE-SMELCAAVEVMEQGVPEKEETPPPVEPEEEEDTEDAGLDDWEAM 509

Query: 242 GSSSHVEWEDA--VHI-IPENESDDEEEEEKGPVSPRTSVGSSEKGGPRGNRSQAQ 294
            S    E  +   VHI + EN  ++EEEEE+      +     E+G   G+    +
Sbjct: 510 ASDEETEKVEGNKVHIEVKENPEEEEEEEEEEEEDEESEEEEEEEGESEGSEGDEE 565



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 35/176 (19%), Positives = 76/176 (43%), Gaps = 16/176 (9%)

Query: 64  KDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSL 123
           +D  +  +  +L+ KE   + +L  A E+ +  V     E+E T    +  E  D   + 
Sbjct: 447 EDKKRKKIPQQLESKEVSESMELCAAVEVMEQGV----PEKEETPPPVEPEEEEDTEDAG 502

Query: 124 NEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQ 183
            +  +A+ + +E +K +G  +  ++ E          +   E + +++ED + E  E+ +
Sbjct: 503 LDDWEAMASDEETEKVEGNKVHIEVKEN--------PEEEEEEEEEEEEDEESEEEEEEE 554

Query: 184 KSSSPREMQKAEEKEVPE----DSLEECAITCSNSHGPYDSNQPHRKTKITFEEDK 235
             S   E  + +EK   E     +L++      +S   YDS+    K +  +++ K
Sbjct: 555 GESEGSEGDEEDEKVSDEKDSGKTLDKKPSKEMSSDSEYDSDDDRTKEERAYDKAK 610



 Score = 30.0 bits (66), Expect = 2.6
 Identities = 39/219 (17%), Positives = 96/219 (43%), Gaps = 25/219 (11%)

Query: 53  KQQNKYKYEECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREK 112
           K++ K  ++E  D++K +    L+      A+ +K   E    K   +++E E T   +K
Sbjct: 46  KEKKKQDFDE-DDILKELEELSLE------AQGIKADRETVAVKPTENNEE-EFTSKDKK 97

Query: 113 LREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDE 172
            +  +   +S              D +  ++L+++ ++  + A+  V+  S  +D+DD  
Sbjct: 98  KKGQKGKKQSF-------------DDNDSEELEDKDSKSKKTAKPKVEMYSGSDDDDDFN 144

Query: 173 DVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQ--PHRKTKIT 230
            +  +   K QKS+  ++   +EE E     ++E +   S+     +S++    RK +  
Sbjct: 145 KLPKKAKGKAQKSN--KKWDGSEEDEDNSKKIKERSRINSSGESGDESDEFLQSRKGQKK 202

Query: 231 FEEDKVDSTLIGSSSHVEWEDAVHIIPENESDDEEEEEK 269
            +++K    +   +   +    +  + + +++ +E E K
Sbjct: 203 NQKNKPGPNIESGNEDDDASFKIKTVAQKKAEKKERERK 241


>gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens]
          Length = 2230

 Score = 47.4 bits (111), Expect = 2e-05
 Identities = 55/214 (25%), Positives = 103/214 (48%), Gaps = 29/214 (13%)

Query: 11   EKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDL---- 66
            +K    I+ + + LR    E +Q+   LK++        +  +++ K K E+ +DL    
Sbjct: 1940 QKLGKEIVRLQKDLRMLRKEHQQELEILKKE--------YDQEREEKIKQEQ-EDLELKH 1990

Query: 67   ---IKSMLRN---ELQFKEEKLA----EQLKQAEELRQYKVLVHSQERELTQLREKLRE- 115
               +K ++R    +L  KE++L     E + +A+E+     L+ S + E  QL +K+ E 
Sbjct: 1991 NSTLKQLMREFNTQLAQKEQELEMTIKETINKAQEVEAE--LLESHQEETNQLLKKIAEK 2048

Query: 116  GRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAE-GCRLAQHLVQKLSPENDNDDDEDV 174
              D  R+   + + L   +E   ++ +DLQ QL E   +  Q L Q+ +P NDN    ++
Sbjct: 2049 DDDLKRTAKRYEEILDAREEEMTAKVRDLQTQLEELQKKYQQKLEQEENPGNDNVTIMEL 2108

Query: 175  QVEVAEKVQ--KSSSPREMQKAEEKEVPEDSLEE 206
            Q ++A+K      S  +E +  E+    ED L++
Sbjct: 2109 QTQLAQKTTLISDSKLKEQEFREQIHNLEDRLKK 2142



 Score = 40.4 bits (93), Expect = 0.002
 Identities = 38/134 (28%), Positives = 69/134 (51%), Gaps = 9/134 (6%)

Query: 2   VVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFR---SLKEKCFVTQLAGFLAKQQNKY 58
           VV     SSE+    + +++EK   +LA K+Q+       +E+ F  Q+   L K Q++Y
Sbjct: 466 VVDVMKKSSEEQIAKLQKLHEK---ELARKEQELTKKLQTREREFQEQMKVALEKSQSEY 522

Query: 59  -KYEECKDLIKSMLRNELQF-KEEKLAEQLKQAEELRQYKVLVHSQEREL-TQLREKLRE 115
            K  + K+  +S+   EL+  K+  L E   +  +L+Q      ++  EL + L + L+E
Sbjct: 523 LKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTRILELESSLEKSLQE 582

Query: 116 GRDASRSLNEHLQA 129
            ++ S+ L  HL+A
Sbjct: 583 NKNQSKDLAVHLEA 596



 Score = 37.0 bits (84), Expect = 0.021
 Identities = 48/193 (24%), Positives = 84/193 (43%), Gaps = 26/193 (13%)

Query: 24  LRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSMLRNELQFKEEKLA 83
           L+ +L+  KQ+   + +K    Q+A    K Q  ++ E  +   +  L  +LQ +E +  
Sbjct: 455 LQQELSRVKQEVVDVMKKSSEEQIA----KLQKLHEKELARK--EQELTKKLQTREREFQ 508

Query: 84  EQLKQAEELRQYKVLVHSQEREL--------TQLREK--LREGRDASRSLNEHLQALLTP 133
           EQ+K A E  Q + L  SQE+E          +L++K  L E  +  R L +  +   T 
Sbjct: 509 EQMKVALEKSQSEYLKISQEKEQQESLALEELELQKKAILTESENKLRDLQQEAETYRTR 568

Query: 134 D-EPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPREMQ 192
             E + S  + LQE   +   LA HL  + +  N          E+   V+K  +  E  
Sbjct: 569 ILELESSLEKSLQENKNQSKDLAVHLEAEKNKHNK---------EITVMVEKHKTELESL 619

Query: 193 KAEEKEVPEDSLE 205
           K ++  +  + L+
Sbjct: 620 KHQQDALWTEKLQ 632



 Score = 36.2 bits (82), Expect = 0.036
 Identities = 53/234 (22%), Positives = 108/234 (46%), Gaps = 36/234 (15%)

Query: 12   KAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKY--EECKDLIKS 69
            KAE  I  I ++L  Q+ EK++Q++   E   +++L   L +++ +     E+ K +  S
Sbjct: 1643 KAEQKIAAIKKQLLSQMEEKEEQYKKGTES-HLSELNTKLQEREREVHILEEKLKSVESS 1701

Query: 70   MLRNELQFKEEKLAEQLKQAEEL-------RQYKVLVHSQERELTQLREKL--REGRDAS 120
                 +  +  K      + EE        + Y+  +   +R LT+ +EKL  R G++  
Sbjct: 1702 QSETLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTE-KEKLLQRVGQEKE 1760

Query: 121  RSLNEHL-------QALLTPDEPDKSQGQD------LQEQLAEGCR-----LAQHLVQKL 162
             +++ H        + L+  +  +  Q +D      LQE+L E  +     +AQH V+K 
Sbjct: 1761 ETVSSHFEMRCQYQERLIKLEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQH-VEKE 1819

Query: 163  SPENDNDDDEDVQVEVAEKVQKSSSPREMQ-KAEEKEVPEDSLEECAITCSNSH 215
              +N+    ++++  V + VQK+   +E+  +  E+++ E  L+ C +     H
Sbjct: 1820 GGKNNIQAKQNLE-NVFDDVQKTLQEKELTCQILEQKIKE--LDSCLVRQKEVH 1870



 Score = 35.8 bits (81), Expect = 0.047
 Identities = 54/227 (23%), Positives = 96/227 (42%), Gaps = 30/227 (13%)

Query: 11   EKAEMNILEINEKLRPQLAEKKQQFRSLKE--KCFVTQLAGFLAKQQNKYKYEECKDLIK 68
            E A+ N   I++ +      +K+Q  SL E  +  +  +     K+ N+   E     ++
Sbjct: 1005 EMAQANSAGISDAVSRLETNQKEQIESLTEVHRRELNDVISIWEKKLNQQAEE-----LQ 1059

Query: 69   SMLRNELQFKEEKLAEQLKQA------------EELRQYKVLVHSQERELTQLREKLREG 116
             +   +LQ KE+++AE LKQ             +E+   K     Q+  L +L+E+L++ 
Sbjct: 1060 EIHEIQLQEKEQEVAE-LKQKILLFGCEKEEMNKEITWLKEEGVKQDTTLNELQEQLKQK 1118

Query: 117  RDASRSLNE-------HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-- 167
                 SL +       HL+ L         +   LQEQL E   LA+   +K+S      
Sbjct: 1119 SAHVNSLAQDETKLKAHLEKLEVDLNKSLKENTFLQEQLVELKMLAEEDKRKVSELTSKL 1178

Query: 168  NDDDEDVQVEVAEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNS 214
               DE+ Q  +    +KS+   E +  E K++ E+   +  I C  +
Sbjct: 1179 KTTDEEFQ-SLKSSHEKSNKSLEDKSLEFKKLSEELAIQLDICCKKT 1224



 Score = 35.4 bits (80), Expect = 0.061
 Identities = 34/120 (28%), Positives = 58/120 (48%), Gaps = 10/120 (8%)

Query: 14   EMNILEIN-EKLRPQLAEKKQQFRSLKE--KCFVTQLAGFLAKQQNKYKYEECKDLIKSM 70
            E N L I+ ++   QL EK+ Q +S+K   +  VT+      +  N+ +    K+   + 
Sbjct: 1284 EQNTLNISFQQATHQLEEKENQIKSMKADIESLVTEKEALQKEGGNQQQAASEKESCITQ 1343

Query: 71   LRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQAL 130
            L+ EL    E +       EEL++ KV + S  ++LT L  +L+     S SL+E   A+
Sbjct: 1344 LKKELS---ENINAVTLMKEELKEKKVEISSLSKQLTDLNVQLQN----SISLSEKEAAI 1396



 Score = 33.9 bits (76), Expect = 0.18
 Identities = 46/218 (21%), Positives = 100/218 (45%), Gaps = 29/218 (13%)

Query: 7   PLSSEKAEMNILE-INEKLRPQ---LAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEE 62
           P+  +   +  LE + ++++ Q   L   K+  +S KE+C +      L  ++     E 
Sbjct: 270 PVVEDGTSVKTLETLQQRVKRQENLLKRCKETIQSHKEQCTL------LTSEK-----EA 318

Query: 63  CKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQ-LREKLREGRDASR 121
            ++ +   L+   + K+  +AE+ K   +LR  K L+   E++    + E  R+  +   
Sbjct: 319 LQEQLDERLQELEKIKDLHMAEKTKLITQLRDAKNLIEQLEQDKGMVIAETKRQMHETLE 378

Query: 122 SLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLA-QHLVQKLSPENDNDD-------DED 173
              E +  L +  +   +QG++L+EQ  +  R A + L + LS     ++       + D
Sbjct: 379 MKEEEIAQLRSRIKQMTTQGEELREQKEKSERAAFEELEKALSTAQKTEEARRKLKAEMD 438

Query: 174 VQVEVAEKV---QKSSSPREMQKAEEK--EVPEDSLEE 206
            Q++  EK    ++ S  +E+ + +++  +V + S EE
Sbjct: 439 EQIKTIEKTSEEERISLQQELSRVKQEVVDVMKKSSEE 476



 Score = 32.7 bits (73), Expect = 0.40
 Identities = 42/197 (21%), Positives = 87/197 (44%), Gaps = 20/197 (10%)

Query: 4   SAGPLSSEKAEMNILEINEKL-RPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEE 62
           S G L    A++++ +  +     Q    ++Q   L++K    +    L  +Q      +
Sbjct: 789 SEGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLDLETERILLTKQVAEVEAQ 848

Query: 63  CKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRS 122
            KD+   +  +++Q ++  L +QL++     + KV      + LTQ+ E   E  D ++ 
Sbjct: 849 KKDVCTELDAHKIQVQD--LMQQLEKQNSEMEQKV------KSLTQVYESKLE--DGNKE 898

Query: 123 LNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLA-QHLVQKLSPENDNDDDEDVQVEVAEK 181
             +  Q L+        + +++  Q+ EG +   + L QKLS + D+    + + E   K
Sbjct: 899 QEQTKQILV--------EKENMILQMREGQKKEIEILTQKLSAKEDSIHILNEEYETKFK 950

Query: 182 VQKSSSPREMQKAEEKE 198
            Q+    +  QKA+E +
Sbjct: 951 NQEKKMEKVKQKAKEMQ 967


>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
           [Homo sapiens]
          Length = 828

 Score = 47.0 bits (110), Expect = 2e-05
 Identities = 46/201 (22%), Positives = 85/201 (42%), Gaps = 24/201 (11%)

Query: 8   LSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLI 67
           +++E+ +    E+ EKLR   +EK +   ++KE                K K E  K L+
Sbjct: 180 ITNEELKKKNAELQEKLRLAESEKSEIQLNVKEL---------------KRKLERAKFLL 224

Query: 68  KSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHL 127
             +  N LQ       E  +Q EELR+ +  +  QE ++ +  E+LRE     R   E +
Sbjct: 225 PQVQTNTLQ------EEMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKM 278

Query: 128 QALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSS 187
           +         + + ++ +++L E  +L +   Q    E    + E+   E  EK+ +   
Sbjct: 279 RRQEKRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEE 338

Query: 188 ---PREMQKAEEKEVPEDSLE 205
               +E Q  E+++   D  E
Sbjct: 339 RLWEQEKQMREQEQKMRDQEE 359



 Score = 42.7 bits (99), Expect = 4e-04
 Identities = 40/195 (20%), Positives = 92/195 (47%), Gaps = 22/195 (11%)

Query: 12  KAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSML 71
           + E  + E  +K+R Q  +  +Q   L+E+       G + +Q+ K + +E     K + 
Sbjct: 238 RQEEELREQEKKIRKQEEKMWRQEERLREQ------EGKMREQEEKMRRQE-----KRLR 286

Query: 72  RNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALL 131
             E + +E++  ++L++ ++LR+ +  +  QE ++ +  EK+RE  +      E L    
Sbjct: 287 EQEKELREQE--KELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQE 344

Query: 132 TPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPREM 191
                 + + +D +E++ E         ++L  + +   +++   E  EK+Q+    RE 
Sbjct: 345 KQMREQEQKMRDQEERMWE-------QDERLREKEERMREQEKMWEQEEKMQEEERIRER 397

Query: 192 QKAEEKEVPEDSLEE 206
           +K   +E  E+++ E
Sbjct: 398 EKKMREE--EETMRE 410



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 65/302 (21%), Positives = 118/302 (39%), Gaps = 47/302 (15%)

Query: 11  EKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKY--KYEECKDLIK 68
           +K E N+ E  EK   Q     Q+    KEK +  +    + +Q+ K   + E+ +D  +
Sbjct: 416 QKQEENMWEQEEKEWQQ-----QRLPEQKEKLWEQEK---MQEQEEKIWEQEEKIRDQEE 467

Query: 69  SMLRNELQFKEEKLAEQ----LKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLN 124
              + +  +++EK+ EQ     +Q E++R  +  +  QE  + +  E+LRE  +  R   
Sbjct: 468 MWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQK 527

Query: 125 EHLQALLTPDEPDKSQGQ-----DLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVA 179
           +  Q      E  K+Q Q     D +E++ E  R+ +        E    ++E++  E  
Sbjct: 528 KMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMRER-------EKKMREEEEMMREQE 580

Query: 180 EKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDST 239
           EK+Q+       Q+ +  E  E   E+           ++            EEDK+   
Sbjct: 581 EKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQE----------EEDKMQ-- 628

Query: 240 LIGSSSHVEWEDAVHI------IPENESDDEEEEEKGPVSPRTSVGSSEKGGPRGNRSQA 293
                  + WE    +      + E E    E+EEK         G  EK   +  + Q 
Sbjct: 629 ---EQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQG 685

Query: 294 QQ 295
           Q+
Sbjct: 686 QE 687



 Score = 37.7 bits (86), Expect = 0.012
 Identities = 39/198 (19%), Positives = 94/198 (47%), Gaps = 8/198 (4%)

Query: 14  EMNILEINEKLRPQ--LAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSML 71
           E  + E  ++LR Q  L E+++Q +  +EK +  Q      +++  ++ EE     +  +
Sbjct: 289 EKELREQEKELREQKKLREQEEQMQEQEEKMW-EQEEKMREQEEKMWRQEERLWEQEKQM 347

Query: 72  RNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREG---RDASRSLNEHLQ 128
           R + Q   ++     +Q E LR+ +  +  QE+ + +  EK++E    R+  + + E  +
Sbjct: 348 REQEQKMRDQEERMWEQDERLREKEERMREQEK-MWEQEEKMQEEERIREREKKMREEEE 406

Query: 129 ALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSP 188
            +   +E  + Q +++ EQ  +  +  Q L ++     + +  ++ + ++ E+ +K    
Sbjct: 407 TMREQEEKMQKQEENMWEQEEKEWQ-QQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQ 465

Query: 189 REMQKAEEKEVPEDSLEE 206
            EM   E+K   ++ + E
Sbjct: 466 EEMWGQEKKMWRQEKMRE 483


>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo
           sapiens]
          Length = 570

 Score = 45.8 bits (107), Expect = 5e-05
 Identities = 40/190 (21%), Positives = 91/190 (47%), Gaps = 17/190 (8%)

Query: 22  EKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIKSMLRNELQFKEEK 81
           EK+R Q  EK+Q+   ++E+    +    + +Q+ K + +E K  I+      +Q +EEK
Sbjct: 357 EKIREQ-EEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK--IREQ-EEMMQEQEEK 412

Query: 82  LAEQ----LKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPD 137
           + EQ     +Q EE+++ +  +  QE ++ +  +K+RE  +  R   E +Q      E +
Sbjct: 413 MGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQ------EQE 466

Query: 138 KSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSSPREMQKAEEK 197
           +  G+   +   +  ++ +   Q+       +   + + ++ E+ +K     EM + +E+
Sbjct: 467 EKMGEQEGKMCEQEAKMQE---QEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEE 523

Query: 198 EVPEDSLEEC 207
           ++ E   + C
Sbjct: 524 KMWEQEEKMC 533



 Score = 43.5 bits (101), Expect = 2e-04
 Identities = 47/265 (17%), Positives = 120/265 (45%), Gaps = 19/265 (7%)

Query: 12  KAEMNILEINEKLRPQ---LAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEECKDLIK 68
           + E  I E  EK++ Q   + E++++ R  +E  +  +      ++    K E+ ++L +
Sbjct: 292 RQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEE 351

Query: 69  SMLRNE-LQFKEEKLAEQ--LKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNE 125
            M   E ++ +EEK  E+  +++ E+ ++ +  +  QE ++ +  EK+RE  +    + E
Sbjct: 352 KMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEM---MQE 408

Query: 126 HLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKS 185
             + +   +E    Q +++QEQ  +  R  + + ++     + ++    Q E+ ++ ++ 
Sbjct: 409 QEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEK 468

Query: 186 SSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV--DSTLIGS 243
              +E +  E++   ++  E+            +     ++ KI  +E+K+     ++  
Sbjct: 469 MGEQEGKMCEQEAKMQEQEEKMR--------RQEEKIREQEKKIREQEEKIREQEEMMQE 520

Query: 244 SSHVEWEDAVHIIPENESDDEEEEE 268
                WE    +  + E   E+EE+
Sbjct: 521 QEEKMWEQEEKMCEQEEKMQEQEEK 545



 Score = 40.8 bits (94), Expect = 0.001
 Identities = 54/270 (20%), Positives = 111/270 (41%), Gaps = 8/270 (2%)

Query: 8   LSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEEC--KD 65
           ++ E+ +    ++ EKL+   +EK +   ++KE     + A  L  QQ      +   K+
Sbjct: 202 ITDEELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKE 261

Query: 66  LIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERE--LTQLREKLREGRDASRSL 123
           L     + + Q +E +L  +L Q +E + ++     QERE  + +  EK+RE  +  R  
Sbjct: 262 LQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQ 321

Query: 124 NEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKL-SPENDNDDDEDVQVEVAEKV 182
            E +          +    + +E++ E      H  +K+   E    ++E ++ +   + 
Sbjct: 322 EEMMWEKEEKMRRQEEMMWEKEEKIRE-LEEKMHEQEKIREQEEKRQEEEKIREQEKRQE 380

Query: 183 QKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV--DSTL 240
           Q++   R+ +K  E+E      EE         G  +     ++ ++  +E+K+      
Sbjct: 381 QEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEK 440

Query: 241 IGSSSHVEWEDAVHIIPENESDDEEEEEKG 270
           I        E    I  + E   E+EE+ G
Sbjct: 441 IREQEKKIREQEEKIREQEEMMQEQEEKMG 470



 Score = 35.8 bits (81), Expect = 0.047
 Identities = 60/266 (22%), Positives = 102/266 (38%), Gaps = 44/266 (16%)

Query: 4   SAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGFLAKQQNKYKYEEC 63
           S G  S E  +    +  E LR +L  + Q  R L  +    Q+A + ++   K    E 
Sbjct: 89  SGGCHSPEDEQKASHQHQEALRRELEAQVQTIRILTCQKTELQMALYYSQHAVKQLEGEA 148

Query: 64  KDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSL 123
           +DLI             +L +  K A EL Q    V +Q+++  +  E+L + RDA   L
Sbjct: 149 RDLI------------SRLHDSWKFAGELEQALSAVATQKKKADRYIEELTKERDA---L 193

Query: 124 NEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQ 183
           +  L      DE  K +   LQE+L         LV+         +  ++Q+ V E  +
Sbjct: 194 SLELYRNTITDEELKEKNAKLQEKL--------QLVE--------SEKSEIQLNVKELKR 237

Query: 184 KSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGS 243
           K    + +   ++ +   D L +            +      K +   EE+++ + L   
Sbjct: 238 KLERAKLLLPQQQLQAEADHLGK------------ELQSVSAKLQAQVEENELWNRLNQQ 285

Query: 244 SSHVEWEDAVHIIPENESDDEEEEEK 269
                W      I E E   +E+EEK
Sbjct: 286 QEEKMWRQE-EKIQEREEKIQEQEEK 310


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.305    0.124    0.335 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,173,196
Number of Sequences: 37866
Number of extensions: 605175
Number of successful extensions: 6043
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 171
Number of HSP's successfully gapped in prelim test: 755
Number of HSP's that attempted gapping in prelim test: 4070
Number of HSP's gapped (non-prelim): 2179
length of query: 299
length of database: 18,247,518
effective HSP length: 102
effective length of query: 197
effective length of database: 14,385,186
effective search space: 2833881642
effective search space used: 2833881642
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 43 (22.0 bits)
S2: 61 (28.1 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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