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Search of human proteins with 239582743
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|239582743 RAN binding protein 3-like isoform 2 [Homo
sapiens]
(465 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|239582743 RAN binding protein 3-like isoform 2 [Homo sapiens] 924 0.0
gi|239582745 RAN binding protein 3-like isoform 1 [Homo sapiens] 910 0.0
gi|194097489 RAN binding protein 3 isoform RANBP3-b [Homo sapiens] 248 8e-66
gi|6466466 RAN binding protein 3 isoform RANBP3-d [Homo sapiens] 235 6e-62
gi|194097487 RAN binding protein 3 isoform RANBP3-a [Homo sapiens] 233 2e-61
gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapi... 54 4e-07
gi|118200331 RANBP2-like and GRIP domain containing 2 [Homo sapi... 54 4e-07
gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapi... 54 4e-07
gi|221307607 RANBP2-like and GRIP domain containing 3 [Homo sapi... 48 2e-05
gi|169162953 PREDICTED: RANBP2-like and GRIP domain containing 8... 47 3e-05
gi|83267877 RANBP2-like and GRIP domain containing 5 isoform 1 [... 47 5e-05
gi|182765478 RANBP2-like and GRIP domain containing 6 [Homo sapi... 47 5e-05
gi|150418007 RAN binding protein 2 [Homo sapiens] 45 1e-04
gi|4506407 RAN binding protein 1 [Homo sapiens] 34 0.32
gi|61743980 stabilin 2 precursor [Homo sapiens] 33 0.55
gi|4507575 tumor necrosis factor receptor 1 precursor [Homo sapi... 32 1.6
gi|24497447 nucleoporin 50kDa isoform a [Homo sapiens] 32 1.6
gi|24497451 nucleoporin 50kDa isoform b [Homo sapiens] 32 1.6
gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 30 6.1
gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 30 6.1
gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens] 30 6.1
gi|221316586 BSD domain containing 1 isoform d [Homo sapiens] 30 6.1
gi|221316584 BSD domain containing 1 isoform c [Homo sapiens] 30 6.1
gi|221316581 BSD domain containing 1 isoform a [Homo sapiens] 30 6.1
gi|221316578 BSD domain containing 1 isoform b [Homo sapiens] 30 6.1
gi|203096856 kinesin family member 7 [Homo sapiens] 30 6.1
gi|7019499 peroxisome proliferator-activated receptor gamma, coa... 29 7.9
gi|217416354 sphingosine kinase type 1-interacting protein isofo... 29 7.9
gi|217416352 sphingosine kinase type 1-interacting protein isofo... 29 7.9
>gi|239582743 RAN binding protein 3-like isoform 2 [Homo sapiens]
Length = 465
Score = 924 bits (2388), Expect = 0.0
Identities = 465/465 (100%), Positives = 465/465 (100%)
Query: 1 MTTIPRKGSSHLPGSLHTCKLKLQEDRRQQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEA 60
MTTIPRKGSSHLPGSLHTCKLKLQEDRRQQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEA
Sbjct: 1 MTTIPRKGSSHLPGSLHTCKLKLQEDRRQQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEA 60
Query: 61 AEPECNGFPTKRVRSSSFTFHITDSQSQGVRKNNVFMTSALVQSSVDIKSAEQGPVKHSK 120
AEPECNGFPTKRVRSSSFTFHITDSQSQGVRKNNVFMTSALVQSSVDIKSAEQGPVKHSK
Sbjct: 61 AEPECNGFPTKRVRSSSFTFHITDSQSQGVRKNNVFMTSALVQSSVDIKSAEQGPVKHSK 120
Query: 121 HVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNSYLLSENLSRARISV 180
HVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNSYLLSENLSRARISV
Sbjct: 121 HVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNSYLLSENLSRARISV 180
Query: 181 QLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQPQLENDSYAK 240
QLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQPQLENDSYAK
Sbjct: 181 QLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQPQLENDSYAK 240
Query: 241 EKPFKSIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVL 300
EKPFKSIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVL
Sbjct: 241 EKPFKSIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVL 300
Query: 301 KINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQ 360
KINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQ
Sbjct: 301 KINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQ 360
Query: 361 MKIQRANHKNVRITATDLEDYSIKIFLIQASAQDTAYLYAAIHHRLVALQSFNKQRDVNQ 420
MKIQRANHKNVRITATDLEDYSIKIFLIQASAQDTAYLYAAIHHRLVALQSFNKQRDVNQ
Sbjct: 361 MKIQRANHKNVRITATDLEDYSIKIFLIQASAQDTAYLYAAIHHRLVALQSFNKQRDVNQ 420
Query: 421 AESLSETAQQLNCESCDENEDDFIQVTKNGSDPSSWTHRQSVACS 465
AESLSETAQQLNCESCDENEDDFIQVTKNGSDPSSWTHRQSVACS
Sbjct: 421 AESLSETAQQLNCESCDENEDDFIQVTKNGSDPSSWTHRQSVACS 465
>gi|239582745 RAN binding protein 3-like isoform 1 [Homo sapiens]
Length = 490
Score = 910 bits (2352), Expect = 0.0
Identities = 465/490 (94%), Positives = 465/490 (94%), Gaps = 25/490 (5%)
Query: 1 MTTIPRKGSSHLPGSLHTCKLKLQEDRRQQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEA 60
MTTIPRKGSSHLPGSLHTCKLKLQEDRRQQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEA
Sbjct: 1 MTTIPRKGSSHLPGSLHTCKLKLQEDRRQQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEA 60
Query: 61 AEPECNGFPTKRVRSSSFTFHITDSQSQGV-------------------------RKNNV 95
AEPECNGFPTKRVRSSSFTFHITDSQSQGV RKNNV
Sbjct: 61 AEPECNGFPTKRVRSSSFTFHITDSQSQGVSTLSQKQMRCSSVTNLPTFPHSGPVRKNNV 120
Query: 96 FMTSALVQSSVDIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKE 155
FMTSALVQSSVDIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKE
Sbjct: 121 FMTSALVQSSVDIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKE 180
Query: 156 KTNNKISEGNSYLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFG 215
KTNNKISEGNSYLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFG
Sbjct: 181 KTNNKISEGNSYLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFG 240
Query: 216 ENMVERVLGTQKLTQPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLIESAAAFS 275
ENMVERVLGTQKLTQPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLIESAAAFS
Sbjct: 241 ENMVERVLGTQKLTQPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLIESAAAFS 300
Query: 276 SQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCG 335
SQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCG
Sbjct: 301 SQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCG 360
Query: 336 TLQSRLIMRNQGSLRLILNSKLWAQMKIQRANHKNVRITATDLEDYSIKIFLIQASAQDT 395
TLQSRLIMRNQGSLRLILNSKLWAQMKIQRANHKNVRITATDLEDYSIKIFLIQASAQDT
Sbjct: 361 TLQSRLIMRNQGSLRLILNSKLWAQMKIQRANHKNVRITATDLEDYSIKIFLIQASAQDT 420
Query: 396 AYLYAAIHHRLVALQSFNKQRDVNQAESLSETAQQLNCESCDENEDDFIQVTKNGSDPSS 455
AYLYAAIHHRLVALQSFNKQRDVNQAESLSETAQQLNCESCDENEDDFIQVTKNGSDPSS
Sbjct: 421 AYLYAAIHHRLVALQSFNKQRDVNQAESLSETAQQLNCESCDENEDDFIQVTKNGSDPSS 480
Query: 456 WTHRQSVACS 465
WTHRQSVACS
Sbjct: 481 WTHRQSVACS 490
>gi|194097489 RAN binding protein 3 isoform RANBP3-b [Homo sapiens]
Length = 499
Score = 248 bits (633), Expect = 8e-66
Identities = 179/487 (36%), Positives = 251/487 (51%), Gaps = 80/487 (16%)
Query: 26 DRRQQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEAAEP---ECNGF--PTKRVRSSSFTF 80
D +EK IA P+FVF+K ++ KR A + E E E + P KR R+SS T
Sbjct: 3 DLANEEKPAIAPPVFVFQK-DKGQKRSAGGSSPEGGEDSDREDGNYCPPVKRERTSSLT- 60
Query: 81 HITDSQSQGVRKNNVFMTSALVQSSVDIKSA-EQGPVKHSKHVIRPAILQLPQARSCAKV 139
SQS+ L+ Q P + + V+RPA+LQ PQ ++ ++
Sbjct: 61 QFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAVLQAPQPKALSQT 120
Query: 140 RKTFGHKAL----------------------------ESCKTKEKTNNKISEGNSY---- 167
+ G + E C +EK K N+
Sbjct: 121 VPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQKNESSNASEEEA 180
Query: 168 -----------------------LLSENLSRARISVQLSTNQDFLGATSVGCQ----PNE 200
L++E++ A + + D AT+ Q E
Sbjct: 181 CEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNYFLQYISSSLE 240
Query: 201 DKCSFKSCSSN-FVFGENMVERVLGTQKLTQPQLE--NDSYAKEKPFKSIPKFPVNFLSS 257
+ + SSN FVFG+NM ERVL KL + + ++ A E +S SS
Sbjct: 241 NSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSES---------SS 291
Query: 258 RTDSIKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWI 317
+ + + SL ESAAA++ +RKCLLEK++VITGEE E NVL++ CKLF+F+KT+QSW+
Sbjct: 292 QEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLFVFDKTSQSWV 351
Query: 318 ERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQRANHKNVRITATD 377
ERGRG LRLND ASTD GTLQSRL+MR QGSLRLILN+KLWAQM+I +A+ K++RITA D
Sbjct: 352 ERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKASEKSIRITAMD 411
Query: 378 LEDYSIKIFLIQASAQDTAYLYAAIHHRLVALQSFNKQRDVNQAESLSETAQQLNCESCD 437
ED +K+FLI AS++DT LYAA+HHR++AL+S +Q + + A N E D
Sbjct: 412 TEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPGAAPSN-EEDD 470
Query: 438 ENEDDFI 444
++DD +
Sbjct: 471 SDDDDVL 477
>gi|6466466 RAN binding protein 3 isoform RANBP3-d [Homo sapiens]
Length = 567
Score = 235 bits (600), Expect = 6e-62
Identities = 163/439 (37%), Positives = 228/439 (51%), Gaps = 74/439 (16%)
Query: 69 PTKRVRSSSFTFHITDSQSQGVRKNNVFMTSALVQSSVDIKSA-EQGPVKHSKHVIRPAI 127
P KR R+SS T SQS+ L+ Q P + + V+RPA+
Sbjct: 118 PVKRERTSSLT-QFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAV 176
Query: 128 LQLPQARSCAKVRKTFGHKAL----------------------------ESCKTKEKTNN 159
LQ PQ ++ ++ + G + E C +EK
Sbjct: 177 LQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEVCALEEKEPQ 236
Query: 160 KISEGNSY---------------------------LLSENLSRARISVQLSTNQDFLGAT 192
K N+ L++E++ A + + D AT
Sbjct: 237 KNESSNASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTAT 296
Query: 193 SVGCQ----PNEDKCSFKSCSSN-FVFGENMVERVLGTQKLTQPQLE--NDSYAKEKPFK 245
+ Q E+ + SSN FVFG+NM ERVL KL + + ++ A E +
Sbjct: 297 NYFLQYISSSLENSTNSADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSE 356
Query: 246 SIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVLKINCK 305
S SS+ + + SL ESAAA++ +RKCLLEK++VITGEE E NVL++ CK
Sbjct: 357 S---------SSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCK 407
Query: 306 LFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQR 365
LF+F+KT+QSW+ERGRG LRLND ASTD GTLQSRL+MR QGSLRLILN+KLWAQM+I +
Sbjct: 408 LFVFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDK 467
Query: 366 ANHKNVRITATDLEDYSIKIFLIQASAQDTAYLYAAIHHRLVALQSFNKQRDVNQAESLS 425
A+ K++RITA D ED +K+FLI AS++DT LYAA+HHR++AL+S +Q + +
Sbjct: 468 ASEKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPE 527
Query: 426 ETAQQLNCESCDENEDDFI 444
A N E D ++DD +
Sbjct: 528 PGAAPSN-EEDDSDDDDVL 545
>gi|194097487 RAN binding protein 3 isoform RANBP3-a [Homo sapiens]
Length = 562
Score = 233 bits (595), Expect = 2e-61
Identities = 160/437 (36%), Positives = 225/437 (51%), Gaps = 75/437 (17%)
Query: 69 PTKRVRSSSFTFHITDSQSQGVRKNNVFMTSALVQSSVDIKSA-EQGPVKHSKHVIRPAI 127
P KR R+SS T SQS+ L+ Q P + + V+RPA+
Sbjct: 118 PVKRERTSSLT-QFPPSQSEERSSGFRLKPPTLIHGQAPSAGLPSQKPKEQQRSVLRPAV 176
Query: 128 LQLPQARSCAKVRKTFGHKAL--------------------------------------- 148
LQ PQ ++ ++ + G +
Sbjct: 177 LQAPQPKALSQTVPSSGTNGVSLPADCTGAVPAASPDTAAWRSPSEAADEEKEPQKNESS 236
Query: 149 -----ESCKTKEKTNNK--------------ISEGNSYLLSENLSRARISVQLSTNQDFL 189
E+C+ K+ + I+E EN +TN FL
Sbjct: 237 NASEEEACEKKDPATQQAFVFGQNLRDRVKLINESVDEADMENAGHPSADTPTATNY-FL 295
Query: 190 GATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQPQLE--NDSYAKEKPFKSI 247
S + + + S + S+ FVFG+NM ERVL KL + + ++ A E +S
Sbjct: 296 QYISSSLENSTN--SADASSNKFVFGQNMSERVLSPPKLNEVSSDANRENAAAESGSES- 352
Query: 248 PKFPVNFLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKIDVITGEETEHNVLKINCKLF 307
SS+ + + SL ESAAA++ +RKCLLEK++VITGEE E NVL++ CKLF
Sbjct: 353 --------SSQEATPEKESLAESAAAYTKATARKCLLEKVEVITGEEAESNVLQMQCKLF 404
Query: 308 IFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQRAN 367
+F+KT+QSW+ERGRG LRLND ASTD GTLQSRL+MR QGSLRLILN+KLWAQM+I +A+
Sbjct: 405 VFDKTSQSWVERGRGLLRLNDMASTDDGTLQSRLVMRTQGSLRLILNTKLWAQMQIDKAS 464
Query: 368 HKNVRITATDLEDYSIKIFLIQASAQDTAYLYAAIHHRLVALQSFNKQRDVNQAESLSET 427
K++RITA D ED +K+FLI AS++DT LYAA+HHR++AL+S +Q + +
Sbjct: 465 EKSIRITAMDTEDQGVKVFLISASSKDTGQLYAALHHRILALRSRVEQEQEAKMPAPEPG 524
Query: 428 AQQLNCESCDENEDDFI 444
A N E D ++DD +
Sbjct: 525 AAPSN-EEDDSDDDDVL 540
>gi|157266273 RANBP2-like and GRIP domain containing 1 [Homo sapiens]
Length = 1756
Score = 53.5 bits (127), Expect = 4e-07
Identities = 78/336 (23%), Positives = 136/336 (40%), Gaps = 34/336 (10%)
Query: 113 QGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKIS-EGNSYLLSE 171
Q P +S++++RPA A V T G E TKE + +S +G + +SE
Sbjct: 872 QSPAYNSQYLLRPA----------ANVTPTKGSSNTEFKSTKEGFSIAVSADGFKFGISE 921
Query: 172 NLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLT-- 229
++ + S + N A + Q N F SS F F + V + +
Sbjct: 922 PGNQEKKSEKPLENDTGFQAQDISGQKNGRGVIFGQTSSTFTFAD--VAKSTSGEGFQFG 979
Query: 230 --QPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLI--ESAAAFSSQPSRKCLLE 285
P + S A EK F S N ++ D K+ E + +P + + E
Sbjct: 980 KKDPNFKGFSGAGEKLFSSQCGKMANKANTSGDFEKDDDACKTEDSDDIHFEPVVQ-MPE 1038
Query: 286 KIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRN 345
K++++TGEE E + KLF F+ W ERG G L++ + R++MR
Sbjct: 1039 KVELVTGEEGEKVLYSQGVKLFRFDAEISQWKERGLGNLKILKNEVNG----KPRMLMRR 1094
Query: 346 QGSLRLILNSKLWAQMKIQ--RANHKNVRITATDLEDYSIKIFLIQAS------AQDTAY 397
L++ N + M ++ + + A+D D K+ + A A++
Sbjct: 1095 DQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGDAKLERLAAQFKTPELAEEFKQ 1154
Query: 398 LYAAIHHRL--VALQSFNKQRDVNQAESLSETAQQL 431
+ L + LQ+ +K D +A L + A+++
Sbjct: 1155 KFEECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEM 1190
Score = 44.3 bits (103), Expect = 2e-04
Identities = 43/191 (22%), Positives = 74/191 (38%), Gaps = 39/191 (20%)
Query: 283 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 342
L + ++V +GEE E V +L+ ++K W ERG G +++ Q R++
Sbjct: 1333 LPDLVEVSSGEENEQVVFSHRAELYRYDKDVGQWKERGIGDIKILQNYDNK----QVRIV 1388
Query: 343 MRNQGSLRLILNSKLWAQMKIQ---------------------RANHKNVRITATDLEDY 381
MR L+L N ++ M +Q + H VR D+ D
Sbjct: 1389 MRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADS 1448
Query: 382 SIKIFLIQASAQDTAYLYAAIHHR-------------LVALQSFNKQR-DVNQAESLSET 427
KIF +AQ+ L R + L+ ++R DV Q + +++
Sbjct: 1449 FKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAVLEETTRERTDVIQGDDVADA 1508
Query: 428 AQQLNCESCDE 438
A ++ S E
Sbjct: 1509 ASEVEVSSTSE 1519
>gi|118200331 RANBP2-like and GRIP domain containing 2 [Homo
sapiens]
Length = 1013
Score = 53.5 bits (127), Expect = 4e-07
Identities = 78/336 (23%), Positives = 136/336 (40%), Gaps = 34/336 (10%)
Query: 113 QGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKIS-EGNSYLLSE 171
Q P +S++++RPA A V T G E TKE + +S +G + +SE
Sbjct: 129 QSPAYNSQYLLRPA----------ANVTPTKGSSNTEFKSTKEGFSIAVSADGFKFGISE 178
Query: 172 NLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLT-- 229
++ + S + N A + Q N F SS F F + V + +
Sbjct: 179 PGNQEKKSEKPLENDTGFQAQDISGQKNGRGVIFGQTSSTFTFAD--VAKSTSGEGFQFG 236
Query: 230 --QPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLI--ESAAAFSSQPSRKCLLE 285
P + S A EK F S N ++ D K+ E + +P + + E
Sbjct: 237 KKDPNFKGFSGAGEKLFSSQCGKMANKANTSGDFEKDDDACKTEDSDDIHFEPVVQ-MPE 295
Query: 286 KIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRN 345
K++++TGEE E + KLF F+ W ERG G L++ + R++MR
Sbjct: 296 KVELVTGEEGEKVLYSQGVKLFRFDAEISQWKERGLGNLKILKNEVNG----KPRMLMRR 351
Query: 346 QGSLRLILNSKLWAQMKIQ--RANHKNVRITATDLEDYSIKIFLIQAS------AQDTAY 397
L++ N + M ++ + + A+D D K+ + A A++
Sbjct: 352 DQVLKVCANHWITTTMNLKPLSGSDRAWMWLASDFSDGDAKLERLAAQFKTPELAEEFKQ 411
Query: 398 LYAAIHHRL--VALQSFNKQRDVNQAESLSETAQQL 431
+ L + LQ+ +K D +A L + A+++
Sbjct: 412 KFEECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEM 447
Score = 43.5 bits (101), Expect = 4e-04
Identities = 43/191 (22%), Positives = 74/191 (38%), Gaps = 39/191 (20%)
Query: 283 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 342
L + ++V +GEE E V +L+ ++K W ERG G +++ Q R++
Sbjct: 590 LPDLVEVSSGEENEQVVFSHMAELYRYDKDVGQWKERGIGDIKILQNYDNK----QVRIV 645
Query: 343 MRNQGSLRLILNSKLWAQMKIQ---------------------RANHKNVRITATDLEDY 381
MR L+L N ++ M +Q + H VR D+ D
Sbjct: 646 MRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADS 705
Query: 382 SIKIFLIQASAQDTAYLYAAIHHR-------------LVALQSFNKQR-DVNQAESLSET 427
KIF +AQ+ L R + L+ ++R DV Q + +++
Sbjct: 706 FKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAVLEETTRERTDVIQGDDVADA 765
Query: 428 AQQLNCESCDE 438
A ++ S E
Sbjct: 766 ASEVEVSSTSE 776
>gi|211059431 RANBP2-like and GRIP domain containing 4 [Homo sapiens]
Length = 1758
Score = 53.5 bits (127), Expect = 4e-07
Identities = 77/336 (22%), Positives = 138/336 (41%), Gaps = 34/336 (10%)
Query: 113 QGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKIS-EGNSYLLSE 171
Q P +S++++RPA A V T G E TKE + +S +G + +SE
Sbjct: 880 QSPAYNSQYLLRPA----------ANVTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISE 929
Query: 172 NLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLT-- 229
++ + S + N A + Q N F SS F F + V + +
Sbjct: 930 PGNQEKESEKPLENDTGFQAQDISGQKNGRGVIFGQTSSTFTFAD--VAKSTSGEGFQFG 987
Query: 230 --QPQLENDSYAKEKPFKSIPKFPVNFLSSRTDSIKNTSLI--ESAAAFSSQPSRKCLLE 285
P + S A EK F S N ++ D K+ E + +P + + E
Sbjct: 988 KKDPNFKGFSGAGEKLFSSQCGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQ-MPE 1046
Query: 286 KIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRN 345
K++++ GEE E + KLF F+ + W ERG G L++ + R++MR
Sbjct: 1047 KVELVIGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNG----KPRMLMRR 1102
Query: 346 QGSLRLILNSKLWAQMKIQ--RANHKNVRITATDLEDYSIKIFLIQAS------AQDTAY 397
+ L++ N + M ++ + + +A+D D K+ + A A++
Sbjct: 1103 EQVLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQ 1162
Query: 398 LYAAIHHRL--VALQSFNKQRDVNQAESLSETAQQL 431
+ L + LQ+ +K D +A L + A+++
Sbjct: 1163 KFEECQQLLLDIPLQTPHKLVDTGRAAKLIQRAEEM 1198
Score = 42.7 bits (99), Expect = 7e-04
Identities = 43/191 (22%), Positives = 73/191 (38%), Gaps = 39/191 (20%)
Query: 283 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 342
L + ++V +GEE E V +L+ ++K W ERG G +++ Q R++
Sbjct: 1341 LPDLVEVSSGEENEKVVFSHRAELYRYDKDVGQWKERGIGDIKILQNYDNK----QVRIV 1396
Query: 343 MRNQGSLRLILNSKLWAQMKIQ---------------------RANHKNVRITATDLEDY 381
MR L+L N + M +Q + H VR D+ D
Sbjct: 1397 MRRDQVLKLCANHTITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADS 1456
Query: 382 SIKIFLIQASAQDTAYLYAAIHHR-------------LVALQSFNKQR-DVNQAESLSET 427
KIF +AQ+ L R + L+ ++R DV Q + +++
Sbjct: 1457 FKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAVLEETTRERTDVIQGDDVADA 1516
Query: 428 AQQLNCESCDE 438
A ++ S E
Sbjct: 1517 ASEVEVSSTSE 1527
>gi|221307607 RANBP2-like and GRIP domain containing 3 [Homo sapiens]
Length = 1758
Score = 48.1 bits (113), Expect = 2e-05
Identities = 74/334 (22%), Positives = 136/334 (40%), Gaps = 30/334 (8%)
Query: 113 QGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKIS-EGNSYLLSE 171
Q P +S++++RPA A V T G E TKE + +S +G + +SE
Sbjct: 880 QSPAYNSQYLLRPA----------ANVTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISE 929
Query: 172 NLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQP 231
++ + S + N L A + + F SS F F + + +
Sbjct: 930 PGNQEKKSEKPLENDTGLQAQDISGRKKGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKK 989
Query: 232 QLENDSY--AKEKPFKSIPKFPVNFLSSRTDSIKNTSLI--ESAAAFSSQPSRKCLLEKI 287
L + A EK F S N ++ D K+ E + +P + + EK+
Sbjct: 990 DLNFKGFSGAGEKLFSSQYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQ-MPEKV 1048
Query: 288 DVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQG 347
+++TGEE E + KLF F+ W ERG G L++ + R++M+ +
Sbjct: 1049 ELVTGEEGEKVLYSQGVKLFRFDAEVSQWKERGLGNLKILKNEVNG----KVRMLMQREQ 1104
Query: 348 SLRLILNSKLWAQMKIQ--RANHKNVRITATDLEDYSIKIFLIQAS------AQDTAYLY 399
L++ N + M ++ + + +A+D D K+ + A A++ +
Sbjct: 1105 VLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKF 1164
Query: 400 AAIHHRL--VALQSFNKQRDVNQAESLSETAQQL 431
L + LQ+ +K D +A L + A+++
Sbjct: 1165 EECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEM 1198
Score = 40.4 bits (93), Expect = 0.003
Identities = 41/191 (21%), Positives = 72/191 (37%), Gaps = 39/191 (20%)
Query: 283 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 342
L + ++V +GEE E V + + ++K W ERG G +++ R++
Sbjct: 1341 LPDLVEVSSGEENEQVVFSHRAEFYRYDKDVGQWKERGIGDIKILQNYDNK----HVRIL 1396
Query: 343 MRNQGSLRLILNSKLWAQMKIQ---------------------RANHKNVRITATDLEDY 381
MR L+L N ++ M +Q + H VR D+ D
Sbjct: 1397 MRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADS 1456
Query: 382 SIKIFLIQASAQDTAYLYAAIHHR-------------LVALQSFNKQR-DVNQAESLSET 427
KIF +AQ+ L R + L+ ++R DV Q + +++
Sbjct: 1457 FKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAVLEETTRERTDVIQGDDVADA 1516
Query: 428 AQQLNCESCDE 438
A ++ S E
Sbjct: 1517 ASEVEVSSTSE 1527
>gi|169162953 PREDICTED: RANBP2-like and GRIP domain containing 8
[Homo sapiens]
Length = 1765
Score = 47.4 bits (111), Expect = 3e-05
Identities = 74/334 (22%), Positives = 136/334 (40%), Gaps = 30/334 (8%)
Query: 113 QGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKIS-EGNSYLLSE 171
Q P +S++++RPA A V T G E TKE + +S +G + +SE
Sbjct: 879 QSPAYNSQYLLRPA----------ANVTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISE 928
Query: 172 NLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQP 231
++ + + N L A + + F SS F F + + +
Sbjct: 929 PGNQEKKREKPLENDTGLQAQDIRGRKKGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKK 988
Query: 232 QLENDSY--AKEKPFKSIPKFPVNFLSSRTDSIKNTSLI--ESAAAFSSQPSRKCLLEKI 287
L + A EK F S N ++ D K+ E + +P + + EK+
Sbjct: 989 DLNFKGFSGAGEKLFSSRYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQ-MPEKV 1047
Query: 288 DVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQG 347
+++TGEE E + KLF F+ + W ERG G L++ + R++MR +
Sbjct: 1048 ELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNG----KLRMLMRREQ 1103
Query: 348 SLRLILNSKLWAQMKIQ--RANHKNVRITATDLEDYSIKIFLIQAS------AQDTAYLY 399
L++ N + M ++ + + +A+D D K+ + A A++ +
Sbjct: 1104 VLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKF 1163
Query: 400 AAIHHRL--VALQSFNKQRDVNQAESLSETAQQL 431
L + LQ+ +K D +A L + A+++
Sbjct: 1164 EECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEM 1197
Score = 44.3 bits (103), Expect = 2e-04
Identities = 42/191 (21%), Positives = 74/191 (38%), Gaps = 39/191 (20%)
Query: 283 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 342
L + ++V +GEE E V +++ ++K W ERG G +++ Q R++
Sbjct: 1340 LPDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKILQNYDNK----QVRIV 1395
Query: 343 MRNQGSLRLILNSKLWAQMKIQ---------------------RANHKNVRITATDLEDY 381
MR L+L N ++ M +Q + H VR D+ D
Sbjct: 1396 MRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADS 1455
Query: 382 SIKIFLIQASAQDTAYLYAAIHHR-------------LVALQSFNKQR-DVNQAESLSET 427
KIF +AQ+ L R + L+ ++R DV Q + +++
Sbjct: 1456 FKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAVLEEITRERTDVIQGDDVADA 1515
Query: 428 AQQLNCESCDE 438
A ++ S E
Sbjct: 1516 ASEVEVSSTSE 1526
>gi|83267877 RANBP2-like and GRIP domain containing 5 isoform 1 [Homo
sapiens]
Length = 1765
Score = 46.6 bits (109), Expect = 5e-05
Identities = 73/334 (21%), Positives = 135/334 (40%), Gaps = 30/334 (8%)
Query: 113 QGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKIS-EGNSYLLSE 171
Q P +S++++RPA A V T G E TKE + +S +G + +SE
Sbjct: 879 QSPAYNSQYLLRPA----------ANVTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISE 928
Query: 172 NLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQP 231
++ + + N A + + F SS F F + + +
Sbjct: 929 PGNQEKKREKPLENDTGFQAQDISGRKKGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKK 988
Query: 232 QLENDSY--AKEKPFKSIPKFPVNFLSSRTDSIKNTSLI--ESAAAFSSQPSRKCLLEKI 287
L + A EK F S N ++ D K+ E + +P + + EK+
Sbjct: 989 DLNFKGFSGAGEKLFSSRYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQ-MPEKV 1047
Query: 288 DVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQG 347
+++TGEE E + KLF F+ + W ERG G L++ + R++MR +
Sbjct: 1048 ELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNG----KLRMLMRREQ 1103
Query: 348 SLRLILNSKLWAQMKIQ--RANHKNVRITATDLEDYSIKIFLIQAS------AQDTAYLY 399
L++ N + M ++ + + +A+D D K+ + A A++ +
Sbjct: 1104 VLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKF 1163
Query: 400 AAIHHRL--VALQSFNKQRDVNQAESLSETAQQL 431
L + LQ+ +K D +A L + A+++
Sbjct: 1164 EECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEM 1197
Score = 43.1 bits (100), Expect = 5e-04
Identities = 42/191 (21%), Positives = 74/191 (38%), Gaps = 39/191 (20%)
Query: 283 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 342
L + ++V +GEE E V +++ ++K W ERG G +++ Q R++
Sbjct: 1340 LPDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKILQNYDNK----QVRIV 1395
Query: 343 MRNQGSLRLILNSKLWAQMKIQ---------------------RANHKNVRITATDLEDY 381
MR L+L N ++ M +Q + H VR D+ D
Sbjct: 1396 MRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADS 1455
Query: 382 SIKIFLIQASAQDTAYLYAAIHHR-------------LVALQSFNKQR-DVNQAESLSET 427
KIF +AQ+ L R + L+ ++R DV Q + +++
Sbjct: 1456 FKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAILEETTRERTDVIQGDDVADA 1515
Query: 428 AQQLNCESCDE 438
A ++ S E
Sbjct: 1516 ASEVEVSSTSE 1526
>gi|182765478 RANBP2-like and GRIP domain containing 6 [Homo sapiens]
Length = 1765
Score = 46.6 bits (109), Expect = 5e-05
Identities = 73/334 (21%), Positives = 135/334 (40%), Gaps = 30/334 (8%)
Query: 113 QGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKIS-EGNSYLLSE 171
Q P +S++++RPA A V T G E TKE + +S +G + +SE
Sbjct: 879 QSPAYNSQYLLRPA----------ANVTPTKGSSNTEFKSTKEGFSIPVSADGFKFGISE 928
Query: 172 NLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQP 231
++ + + N A + + F SS F F + + +
Sbjct: 929 PGNQEKKREKPLENDTGFQAQDISGRKKGRGVIFGQTSSTFTFADVAKSTSGEGFQFGKK 988
Query: 232 QLENDSY--AKEKPFKSIPKFPVNFLSSRTDSIKNTSLI--ESAAAFSSQPSRKCLLEKI 287
L + A EK F S N ++ D K+ E + +P + + EK+
Sbjct: 989 DLNFKGFSGAGEKLFSSRYGKMANKANTSGDFEKDDDAYKTEDSDDIHFEPVVQ-MPEKV 1047
Query: 288 DVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQG 347
+++TGEE E + KLF F+ + W ERG G L++ + R++MR +
Sbjct: 1048 ELVTGEEGEKVLYSQGVKLFRFDAEVRQWKERGLGNLKILKNEVNG----KLRMLMRREQ 1103
Query: 348 SLRLILNSKLWAQMKIQ--RANHKNVRITATDLEDYSIKIFLIQAS------AQDTAYLY 399
L++ N + M ++ + + +A+D D K+ + A A++ +
Sbjct: 1104 VLKVCANHWITTTMNLKPLSGSDRAWMWSASDFSDGDAKLERLAAKFKTPELAEEFKQKF 1163
Query: 400 AAIHHRL--VALQSFNKQRDVNQAESLSETAQQL 431
L + LQ+ +K D +A L + A+++
Sbjct: 1164 EECQRLLLDIPLQTPHKLVDTGRAAKLIQRAEEM 1197
Score = 43.1 bits (100), Expect = 5e-04
Identities = 42/191 (21%), Positives = 74/191 (38%), Gaps = 39/191 (20%)
Query: 283 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 342
L + ++V +GEE E V +++ ++K W ERG G +++ Q R++
Sbjct: 1340 LPDLVEVSSGEENEQVVFSHRAEIYRYDKDVGQWKERGIGDIKILQNYDNK----QVRIV 1395
Query: 343 MRNQGSLRLILNSKLWAQMKIQ---------------------RANHKNVRITATDLEDY 381
MR L+L N ++ M +Q + H VR D+ D
Sbjct: 1396 MRRDQVLKLCANHRITPDMSLQNMKGTERVWVWTACDFADGERKVEHLAVRFKLQDVADS 1455
Query: 382 SIKIFLIQASAQDTAYLYAAIHHR-------------LVALQSFNKQR-DVNQAESLSET 427
KIF +AQ+ L R + L+ ++R DV Q + +++
Sbjct: 1456 FKKIFDEAKTAQEKDSLITPHVSRSSTPRESPCGKIAVAILEETTRERTDVIQGDDVADA 1515
Query: 428 AQQLNCESCDE 438
A ++ S E
Sbjct: 1516 ASEVEVSSTSE 1526
>gi|150418007 RAN binding protein 2 [Homo sapiens]
Length = 3224
Score = 45.1 bits (105), Expect = 1e-04
Identities = 69/304 (22%), Positives = 123/304 (40%), Gaps = 22/304 (7%)
Query: 144 GHKALESCKTKEKTNNKIS-EGNSYLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDK 202
G E TKE + +S +G + +SE ++ + S + N A + Q N
Sbjct: 1876 GSSNTEFKSTKEGFSIPVSADGFKFGISEPGNQEKKSEKPLENGTGFQAQDISGQKNGRG 1935
Query: 203 CSFKSCSSNFVFGENMVERVLGTQ---KLTQPQLENDSYAKEKPFKSIPKFPVNFLSSRT 259
F SS F F + + + G P + S A EK F S N ++
Sbjct: 1936 VIFGQTSSTFTFAD-LAKSTSGEGFQFGKKDPNFKGFSGAGEKLFSSQYGKMANKANTSG 1994
Query: 260 DSIKNTSLI--ESAAAFSSQPSRKCLLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWI 317
D K+ E + +P + + EK++++TGEE E + KLF F+ W
Sbjct: 1995 DFEKDDDAYKTEDSDDIHFEPVVQ-MPEKVELVTGEEDEKVLYSQRVKLFRFDAEVSQWK 2053
Query: 318 ERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLWAQMKIQ--RANHKNVRITA 375
ERG G L++ + R++MR + L++ N + M ++ + + A
Sbjct: 2054 ERGLGNLKILKNEVNG----KLRMLMRREQVLKVCANHWITTTMNLKPLSGSDRAWMWLA 2109
Query: 376 TDLEDYSIKIFLIQAS------AQDTAYLYAAIHHRL--VALQSFNKQRDVNQAESLSET 427
+D D K+ + A A++ + L + LQ+ +K D +A L +
Sbjct: 2110 SDFSDGDAKLEQLAAKFKTPELAEEFKQKFEECQRLLLDIPLQTPHKLVDTGRAAKLIQR 2169
Query: 428 AQQL 431
A+++
Sbjct: 2170 AEEM 2173
Score = 44.3 bits (103), Expect = 2e-04
Identities = 39/155 (25%), Positives = 64/155 (41%), Gaps = 10/155 (6%)
Query: 283 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 342
L + ++V +GEE E V KL+ ++K W ERG G +++ Q R++
Sbjct: 2316 LPDLVEVSSGEENEQVVFSHRAKLYRYDKDVGQWKERGIGDIKILQNYDNK----QVRIV 2371
Query: 343 MRNQGSLRLILNSKLWAQMKIQ--RANHKNVRITATDLEDYSIKI--FLIQASAQDTAYL 398
MR L+L N ++ M +Q + + TA D D K+ ++ QD A
Sbjct: 2372 MRRDQVLKLCANHRITPDMTLQNMKGTERVWLWTACDFADGERKVEHLAVRFKLQDVADS 2431
Query: 399 YAAIHHRLVALQSFNKQRDVNQAESLSETAQQLNC 433
+ I Q K + S S T ++ C
Sbjct: 2432 FKKIFDEAKTAQ--EKDSLITPHVSRSSTPRESPC 2464
Score = 42.4 bits (98), Expect = 0.001
Identities = 26/81 (32%), Positives = 43/81 (53%), Gaps = 4/81 (4%)
Query: 283 LLEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLI 342
L +KI+V TGEE E KLF F+ ++ W ERG G +++ ++ + RL+
Sbjct: 1178 LPDKIEVKTGEEDEEEFFCNRAKLFRFDVESKEWKERGIGNVKILRHKTSG----KIRLL 1233
Query: 343 MRNQGSLRLILNSKLWAQMKI 363
MR + L++ N + MK+
Sbjct: 1234 MRREQVLKICANHYISPDMKL 1254
Score = 38.5 bits (88), Expect = 0.013
Identities = 26/104 (25%), Positives = 50/104 (48%), Gaps = 6/104 (5%)
Query: 284 LEKIDVITGEETEHNVLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIM 343
L +++V +GEE E + K KL+ +++ W ERG G +++ + R++M
Sbjct: 2918 LPEVEVKSGEEDEEILFKERAKLYRWDRDVSQWKERGVGDIKILWHTMKN----YYRILM 2973
Query: 344 RNQGSLRLILNSKLWAQMKIQRANHKNVRI--TATDLEDYSIKI 385
R ++ N + M+++ N N + TA+D D K+
Sbjct: 2974 RRDQVFKVCANHVITKTMELKPLNVSNNALVWTASDYADGEAKV 3017
>gi|4506407 RAN binding protein 1 [Homo sapiens]
Length = 201
Score = 33.9 bits (76), Expect = 0.32
Identities = 24/83 (28%), Positives = 41/83 (49%), Gaps = 6/83 (7%)
Query: 284 LEKIDVITGEETEHNVLKINCKLFIF--NKTTQSWIERGRGTLRLNDTASTDCGTLQSRL 341
L + ++ T EE E + K+ KLF F W ERG G ++L + G + RL
Sbjct: 33 LPEQEIKTLEEDEEELFKMRAKLFRFASENDLPEWKERGTGDVKL--LKHKEKGAI--RL 88
Query: 342 IMRNQGSLRLILNSKLWAQMKIQ 364
+MR +L++ N + M+++
Sbjct: 89 LMRRDKTLKICANHYITPMMELK 111
>gi|61743980 stabilin 2 precursor [Homo sapiens]
Length = 2551
Score = 33.1 bits (74), Expect = 0.55
Identities = 47/191 (24%), Positives = 73/191 (38%), Gaps = 20/191 (10%)
Query: 244 FKSIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQ-----PSRKCLLEKIDVITGEETEHN 298
F S+ F L+ S + + +E S + P L E + ++G + EH+
Sbjct: 2321 FPSLTNFLTEVLAYSNSSARGRAFLEHLTDLSIRGTLFVPQNSGLGEN-ETLSGRDIEHH 2379
Query: 299 VLKINCKLFIFNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSLRLILNSKLW 358
+ N +F +N + R +L TAS D LQ G R IL ++
Sbjct: 2380 LA--NVSMFFYNDLVNGTTLQTRLGSKLLITASQD--PLQPTETRFVDG--RAILQWDIF 2433
Query: 359 AQMKI-------QRANHKNVRITATDL-EDYSIKIFLIQASAQDTAYLYAAIHHRLVALQ 410
A I +A V +T T L I L+ + AY Y I+ R + Q
Sbjct: 2434 ASNGIIHVISRPLKAPPAPVTLTHTGLGAGIFFAIILVTGAVALAAYSYFRINRRTIGFQ 2493
Query: 411 SFNKQRDVNQA 421
F + D+N A
Sbjct: 2494 HFESEEDINVA 2504
>gi|4507575 tumor necrosis factor receptor 1 precursor [Homo
sapiens]
Length = 455
Score = 31.6 bits (70), Expect = 1.6
Identities = 35/136 (25%), Positives = 54/136 (39%), Gaps = 21/136 (15%)
Query: 107 DIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGN- 165
D + E G S++ +R + SC+K RK G + SC T +
Sbjct: 80 DCRECESGSFTASENHLRHCL-------SCSKCRKEMGQVEISSCTVDRDTVCGCRKNQY 132
Query: 166 SYLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGEN------MV 219
+ SENL + + L N G + CQ E + + +C + F EN
Sbjct: 133 RHYWSENLFQC-FNCSLCLN----GTVHLSCQ--EKQNTVCTCHAGFFLRENECVSCSNC 185
Query: 220 ERVLGTQKLTQPQLEN 235
++ L KL PQ+EN
Sbjct: 186 KKSLECTKLCLPQIEN 201
>gi|24497447 nucleoporin 50kDa isoform a [Homo sapiens]
Length = 440
Score = 31.6 bits (70), Expect = 1.6
Identities = 49/186 (26%), Positives = 76/186 (40%), Gaps = 18/186 (9%)
Query: 194 VGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQPQLENDSYAKEKPFKSIPKFPVN 253
V + D S + S++F FG+ + VLG+ L+ L S++ P S
Sbjct: 225 VASEKKTDPSSLGATSASFNFGKKVDSSVLGS--LSSVPLTGFSFS---PGNSSLFGKDT 279
Query: 254 FLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKID-----VITGEETEHNVLKINCKLFI 308
S S T +E A S + E+ D V+T + E CKLF
Sbjct: 280 TQSKPVSSPFPTKPLEGQAEGDSGECKGGDEEENDEPPKVVVTEVKEEDAFYSKKCKLFY 339
Query: 309 FNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSL-RLILNSKLWAQMKIQRAN 367
K + E+G GTL L TA+ +++L++R +L ++LN + M R
Sbjct: 340 --KKDNEFKEKGIGTLHLKPTANQ-----KTQLLVRADTNLGNILLNVLIPPNMPCTRTG 392
Query: 368 HKNVRI 373
NV I
Sbjct: 393 KNNVLI 398
>gi|24497451 nucleoporin 50kDa isoform b [Homo sapiens]
Length = 468
Score = 31.6 bits (70), Expect = 1.6
Identities = 49/186 (26%), Positives = 76/186 (40%), Gaps = 18/186 (9%)
Query: 194 VGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQPQLENDSYAKEKPFKSIPKFPVN 253
V + D S + S++F FG+ + VLG+ L+ L S++ P S
Sbjct: 253 VASEKKTDPSSLGATSASFNFGKKVDSSVLGS--LSSVPLTGFSFS---PGNSSLFGKDT 307
Query: 254 FLSSRTDSIKNTSLIESAAAFSSQPSRKCLLEKID-----VITGEETEHNVLKINCKLFI 308
S S T +E A S + E+ D V+T + E CKLF
Sbjct: 308 TQSKPVSSPFPTKPLEGQAEGDSGECKGGDEEENDEPPKVVVTEVKEEDAFYSKKCKLFY 367
Query: 309 FNKTTQSWIERGRGTLRLNDTASTDCGTLQSRLIMRNQGSL-RLILNSKLWAQMKIQRAN 367
K + E+G GTL L TA+ +++L++R +L ++LN + M R
Sbjct: 368 --KKDNEFKEKGIGTLHLKPTANQ-----KTQLLVRADTNLGNILLNVLIPPNMPCTRTG 420
Query: 368 HKNVRI 373
NV I
Sbjct: 421 KNNVLI 426
>gi|239755011 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1363
Score = 29.6 bits (65), Expect = 6.1
Identities = 37/175 (21%), Positives = 72/175 (41%), Gaps = 23/175 (13%)
Query: 107 DIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNS 166
D++S +Q ++H +++ + Q + K K + K K++ +E N
Sbjct: 343 DLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRK--KLKKRKEGAKAEHNL 400
Query: 167 YLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQ 226
+ SE ++ S N+ + S G + +E +FG M++R +
Sbjct: 401 KVASEEKQER---LERSENKQPQDSQSYGKKKDE------------MFGNFMLKRDIAML 445
Query: 227 KLTQPQLENDSYAKEKPF----KSIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQ 277
K ++NDS KEK + KSI + NF ++ + + + A +S Q
Sbjct: 446 KEELYAIKNDSLRKEKKYIQEIKSITEINANF--EKSVRLNEEMITKKVAQYSQQ 498
>gi|239749555 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1366
Score = 29.6 bits (65), Expect = 6.1
Identities = 37/175 (21%), Positives = 72/175 (41%), Gaps = 23/175 (13%)
Query: 107 DIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNS 166
D++S +Q ++H +++ + Q + K K + K K++ +E N
Sbjct: 372 DLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRK--KLKKRKEGAKAEHNL 429
Query: 167 YLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQ 226
+ SE ++ S N+ + S G + +E +FG M++R +
Sbjct: 430 KVASEEKQER---LERSENKQPQDSQSYGKKKDE------------MFGNFMLKRDIAML 474
Query: 227 KLTQPQLENDSYAKEKPF----KSIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQ 277
K ++NDS KEK + KSI + NF ++ + + + A +S Q
Sbjct: 475 KEELYAIKNDSLRKEKKYIQEIKSITEINANF--EKSVRLNEEMITKKVAQYSQQ 527
>gi|239743705 PREDICTED: ankyrin repeat domain 18B [Homo sapiens]
Length = 1139
Score = 29.6 bits (65), Expect = 6.1
Identities = 37/175 (21%), Positives = 72/175 (41%), Gaps = 23/175 (13%)
Query: 107 DIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNS 166
D++S +Q ++H +++ + Q + K K + K K++ +E N
Sbjct: 372 DLRSIQQQILEHKNKMLKNHLRNDNQETAAMKPENLKKRKKRK--KLKKRKEGAKAEHNL 429
Query: 167 YLLSENLSRARISVQLSTNQDFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQ 226
+ SE ++ S N+ + S G + +E +FG M++R +
Sbjct: 430 KVASEEKQER---LERSENKQPQDSQSYGKKKDE------------MFGNFMLKRDIAML 474
Query: 227 KLTQPQLENDSYAKEKPF----KSIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQ 277
K ++NDS KEK + KSI + NF ++ + + + A +S Q
Sbjct: 475 KEELYAIKNDSLRKEKKYIQEIKSITEINANF--EKSVRLNEEMITKKVAQYSQQ 527
>gi|221316586 BSD domain containing 1 isoform d [Homo sapiens]
Length = 335
Score = 29.6 bits (65), Expect = 6.1
Identities = 38/159 (23%), Positives = 64/159 (40%), Gaps = 17/159 (10%)
Query: 30 QEKSVIAQPIFVFEKGEQTFKRPAEDTLYEAAEPECNGFPTKRVRSSSFTFHITD-SQSQ 88
+E V I F +GE + P E+ L + EP P++ S S I + + +
Sbjct: 142 KEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAP 201
Query: 89 GVRKNNVFMTSALVQSS-------VDIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRK 141
R ++ L+++S VD+ P HSK + P+ R A+V +
Sbjct: 202 EARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARV-E 260
Query: 142 TFGHKA--------LESCKTKEKTNNKISEGNSYLLSEN 172
T +A L S K +N +G+S +SE+
Sbjct: 261 TLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISED 299
>gi|221316584 BSD domain containing 1 isoform c [Homo sapiens]
Length = 374
Score = 29.6 bits (65), Expect = 6.1
Identities = 38/159 (23%), Positives = 64/159 (40%), Gaps = 17/159 (10%)
Query: 30 QEKSVIAQPIFVFEKGEQTFKRPAEDTLYEAAEPECNGFPTKRVRSSSFTFHITD-SQSQ 88
+E V I F +GE + P E+ L + EP P++ S S I + + +
Sbjct: 181 KEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAP 240
Query: 89 GVRKNNVFMTSALVQSS-------VDIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRK 141
R ++ L+++S VD+ P HSK + P+ R A+V +
Sbjct: 241 EARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARV-E 299
Query: 142 TFGHKA--------LESCKTKEKTNNKISEGNSYLLSEN 172
T +A L S K +N +G+S +SE+
Sbjct: 300 TLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISED 338
>gi|221316581 BSD domain containing 1 isoform a [Homo sapiens]
Length = 447
Score = 29.6 bits (65), Expect = 6.1
Identities = 38/159 (23%), Positives = 64/159 (40%), Gaps = 17/159 (10%)
Query: 30 QEKSVIAQPIFVFEKGEQTFKRPAEDTLYEAAEPECNGFPTKRVRSSSFTFHITD-SQSQ 88
+E V I F +GE + P E+ L + EP P++ S S I + + +
Sbjct: 254 KEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAP 313
Query: 89 GVRKNNVFMTSALVQSS-------VDIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRK 141
R ++ L+++S VD+ P HSK + P+ R A+V +
Sbjct: 314 EARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARV-E 372
Query: 142 TFGHKA--------LESCKTKEKTNNKISEGNSYLLSEN 172
T +A L S K +N +G+S +SE+
Sbjct: 373 TLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISED 411
>gi|221316578 BSD domain containing 1 isoform b [Homo sapiens]
Length = 430
Score = 29.6 bits (65), Expect = 6.1
Identities = 38/159 (23%), Positives = 64/159 (40%), Gaps = 17/159 (10%)
Query: 30 QEKSVIAQPIFVFEKGEQTFKRPAEDTLYEAAEPECNGFPTKRVRSSSFTFHITD-SQSQ 88
+E V I F +GE + P E+ L + EP P++ S S I + + +
Sbjct: 237 KEAKVPVAKISTFPEGEPGPQSPCEENLVTSVEPPAEVTPSESSESISLVTQIANPATAP 296
Query: 89 GVRKNNVFMTSALVQSS-------VDIKSAEQGPVKHSKHVIRPAILQLPQARSCAKVRK 141
R ++ L+++S VD+ P HSK + P+ R A+V +
Sbjct: 297 EARVLPKDLSQKLLEASLEEQGLAVDVGETGPSPPIHSKPLTPAGHTGGPEPRPPARV-E 355
Query: 142 TFGHKA--------LESCKTKEKTNNKISEGNSYLLSEN 172
T +A L S K +N +G+S +SE+
Sbjct: 356 TLREEAPTDLRVFELNSDSGKSTPSNNGKKGSSTDISED 394
>gi|203096856 kinesin family member 7 [Homo sapiens]
Length = 1343
Score = 29.6 bits (65), Expect = 6.1
Identities = 25/74 (33%), Positives = 38/74 (51%), Gaps = 4/74 (5%)
Query: 6 RKGSSHLPGSLHTCKLKLQEDRR---QQEKSVIAQPIFVFEKGEQTFKRPAEDTLYEAAE 62
R GS+ SL + K++E ++ Q+ + V+ Q + E GE+ KR A EA
Sbjct: 892 RSGSNGSVVSLEQ-QQKIEEQKKWLDQEMEKVLQQRRALEELGEELHKREAILAKKEALM 950
Query: 63 PECNGFPTKRVRSS 76
E G +KR+RSS
Sbjct: 951 QEKTGLESKRLRSS 964
>gi|7019499 peroxisome proliferator-activated receptor gamma,
coactivator 1 alpha [Homo sapiens]
Length = 798
Score = 29.3 bits (64), Expect = 7.9
Identities = 41/192 (21%), Positives = 65/192 (33%), Gaps = 23/192 (11%)
Query: 129 QLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNSYLLSENLSRARISVQLSTNQDF 188
Q PQ R C+++ K + + T N+ S + + S L
Sbjct: 200 QKPQRRPCSELLKYLTTN--DDPPHTKPTENRNSSRDKCTSKKKSHTQSQSQHLQAKPTT 257
Query: 189 LGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVL-----GTQKLTQPQLENDSYAKEKP 243
L PN+ K S F +ER L GT LT P ++ P
Sbjct: 258 LSLPLTPESPNDPKGS--------PFENKTIERTLSVELSGTAGLTPPTTPPHKANQDNP 309
Query: 244 FKSIPKFPVNFLSSRTDSIKNTSLIESAAAFSSQPSRK--------CLLEKIDVITGEET 295
F++ PK + + K ES+ + ++K L K V+TG
Sbjct: 310 FRASPKLKSSCKTVVPPPSKKPRYSESSGTQGNNSTKKGPEQSELYAQLSKSSVLTGGHE 369
Query: 296 EHNVLKINCKLF 307
E + + +LF
Sbjct: 370 ERKTKRPSLRLF 381
>gi|217416354 sphingosine kinase type 1-interacting protein isoform
1 [Homo sapiens]
Length = 1700
Score = 29.3 bits (64), Expect = 7.9
Identities = 23/110 (20%), Positives = 46/110 (41%), Gaps = 3/110 (2%)
Query: 127 ILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNSYLLSENLSRARISVQLSTNQ 186
+L+ Q R C G+ ++ +CK K +N + E Y L +I ++
Sbjct: 21 VLEPQQGRGCGSSGSGPGN-SITACK-KVLRSNSLLESTDYWLQNQRMPCQIGFVEDKSE 78
Query: 187 DFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQPQLEND 236
+ V N+D+CS + V + +++ + + QP+ EN+
Sbjct: 79 NCASVCFVNLDVNKDECSTEHLQQKLVNVSPDLPKLISSMNVQQPK-ENE 127
>gi|217416352 sphingosine kinase type 1-interacting protein isoform
2 [Homo sapiens]
Length = 1671
Score = 29.3 bits (64), Expect = 7.9
Identities = 23/110 (20%), Positives = 46/110 (41%), Gaps = 3/110 (2%)
Query: 127 ILQLPQARSCAKVRKTFGHKALESCKTKEKTNNKISEGNSYLLSENLSRARISVQLSTNQ 186
+L+ Q R C G+ ++ +CK K +N + E Y L +I ++
Sbjct: 21 VLEPQQGRGCGSSGSGPGN-SITACK-KVLRSNSLLESTDYWLQNQRMPCQIGFVEDKSE 78
Query: 187 DFLGATSVGCQPNEDKCSFKSCSSNFVFGENMVERVLGTQKLTQPQLEND 236
+ V N+D+CS + V + +++ + + QP+ EN+
Sbjct: 79 NCASVCFVNLDVNKDECSTEHLQQKLVNVSPDLPKLISSMNVQQPK-ENE 127
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.315 0.127 0.361
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,571,144
Number of Sequences: 37866
Number of extensions: 666939
Number of successful extensions: 1891
Number of sequences better than 10.0: 29
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 16
Number of HSP's that attempted gapping in prelim test: 1855
Number of HSP's gapped (non-prelim): 47
length of query: 465
length of database: 18,247,518
effective HSP length: 106
effective length of query: 359
effective length of database: 14,233,722
effective search space: 5109906198
effective search space used: 5109906198
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.