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Search of human proteins with 237757300
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|237757300 dihydropyrimidine dehydrogenase isoform 2 [Homo
sapiens]
(173 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|237757300 dihydropyrimidine dehydrogenase isoform 2 [Homo sap... 362 e-101
gi|119943098 dihydropyrimidine dehydrogenase isoform 1 [Homo sap... 340 4e-94
gi|154354987 hook homolog 2 isoform 2 [Homo sapiens] 31 0.61
gi|154354985 hook homolog 2 isoform 1 [Homo sapiens] 31 0.61
gi|194018565 zinc finger protein 100 [Homo sapiens] 30 0.80
gi|24307875 zinc finger protein 33B [Homo sapiens] 30 1.0
gi|169213834 PREDICTED: similar to hCG36734 [Homo sapiens] 29 1.8
gi|169214277 PREDICTED: similar to hCG36734 [Homo sapiens] 29 1.8
gi|169213622 PREDICTED: similar to hCG36734 [Homo sapiens] 29 1.8
gi|54792150 zinc finger protein 473 [Homo sapiens] 29 1.8
gi|54792148 zinc finger protein 473 [Homo sapiens] 29 1.8
gi|226371655 zinc finger family member 674 isoform 2 [Homo sapiens] 29 2.3
gi|89994742 zinc finger family member 674 isoform 1 [Homo sapiens] 29 2.3
gi|212549782 caspase 8 associated protein 2 [Homo sapiens] 29 2.3
gi|6912288 caspase 8 associated protein 2 [Homo sapiens] 29 2.3
gi|212549532 caspase 8 associated protein 2 [Homo sapiens] 29 2.3
gi|194097407 zinc finger protein 680 isoform 1 [Homo sapiens] 28 4.0
gi|28376656 zinc finger, X-linked, duplicated B [Homo sapiens] 28 4.0
gi|118498359 ribosomal L1 domain containing 1 [Homo sapiens] 28 5.2
gi|20336246 proprotein convertase subtilisin/kexin type 5 prepro... 27 8.8
gi|28274709 zinc finger, X-linked, duplicated A [Homo sapiens] 27 8.8
>gi|237757300 dihydropyrimidine dehydrogenase isoform 2 [Homo
sapiens]
Length = 173
Score = 362 bits (930), Expect = e-101
Identities = 173/173 (100%), Positives = 173/173 (100%)
Query: 1 MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFD 60
MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFD
Sbjct: 1 MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFD 60
Query: 61 DIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDN 120
DIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDN
Sbjct: 61 DIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDN 120
Query: 121 PLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATETLILAFSLMNHL 173
PLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATETLILAFSLMNHL
Sbjct: 121 PLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATETLILAFSLMNHL 173
>gi|119943098 dihydropyrimidine dehydrogenase isoform 1 [Homo
sapiens]
Length = 1025
Score = 340 bits (872), Expect = 4e-94
Identities = 161/161 (100%), Positives = 161/161 (100%)
Query: 1 MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFD 60
MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFD
Sbjct: 1 MAPVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFD 60
Query: 61 DIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDN 120
DIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDN
Sbjct: 61 DIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLDIKSFITSIANKNYYGAAKMIFSDN 120
Query: 121 PLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATE 161
PLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATE
Sbjct: 121 PLGLTCGMVCPTSDLCVGGCNLYATEEGPINIGGLQQFATE 161
>gi|154354987 hook homolog 2 isoform 2 [Homo sapiens]
Length = 717
Score = 30.8 bits (68), Expect = 0.61
Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
Query: 46 DKNCFNCEKLENNFDDI---KHTTLGERGALREAMRCLKCA 83
+K F C LE ++ + K L ER +LREA L+CA
Sbjct: 384 EKWLFECRNLEEKYESVTKEKERLLAERDSLREANEELRCA 424
>gi|154354985 hook homolog 2 isoform 1 [Homo sapiens]
Length = 719
Score = 30.8 bits (68), Expect = 0.61
Identities = 16/41 (39%), Positives = 22/41 (53%), Gaps = 3/41 (7%)
Query: 46 DKNCFNCEKLENNFDDI---KHTTLGERGALREAMRCLKCA 83
+K F C LE ++ + K L ER +LREA L+CA
Sbjct: 384 EKWLFECRNLEEKYESVTKEKERLLAERDSLREANEELRCA 424
>gi|194018565 zinc finger protein 100 [Homo sapiens]
Length = 542
Score = 30.4 bits (67), Expect = 0.80
Identities = 21/70 (30%), Positives = 32/70 (45%), Gaps = 6/70 (8%)
Query: 22 TQTHATLCSTSAKKL-----DKKHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALRE- 75
TQ++ C SAK +H R+ K F C+K E +F + H T +R + E
Sbjct: 172 TQSNIFQCDPSAKVFHTFSNSNRHKIRHTRKKPFKCKKCEKSFCMLLHLTQHKRFHITEN 231
Query: 76 AMRCLKCADA 85
+ +C C A
Sbjct: 232 SYQCKDCGKA 241
>gi|24307875 zinc finger protein 33B [Homo sapiens]
Length = 778
Score = 30.0 bits (66), Expect = 1.0
Identities = 29/111 (26%), Positives = 47/111 (42%), Gaps = 13/111 (11%)
Query: 13 ESILALNPRTQT-----HATLCS-TSAKKLD-KKHWKRNPDKNCFNCEKLENNFDDIKHT 65
+S L L+ RT T C T +K D KH + + + + C + +F H
Sbjct: 397 KSALTLHQRTHTGEKPYQCNACGKTFYQKSDLTKHQRTHTGQKPYECYECGKSFCMNSHL 456
Query: 66 TLGERGALREA-MRCLKCADAPCQKS-----CPTNLDIKSFITSIANKNYY 110
T+ +R E CL+C + CQKS T++ K + + K +Y
Sbjct: 457 TVHQRTHTGEKPFECLECGKSFCQKSHLTQHQRTHIGDKPYECNACGKTFY 507
>gi|169213834 PREDICTED: similar to hCG36734 [Homo sapiens]
Length = 560
Score = 29.3 bits (64), Expect = 1.8
Identities = 16/54 (29%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Query: 43 RNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLD 96
R+ N F C++ +F + H T ER R + C KC + S P+ L+
Sbjct: 195 RHTGNNSFKCKECGKSFCMLSHLTKHERNHTR--VNCYKCEECGKAFSVPSKLN 246
>gi|169214277 PREDICTED: similar to hCG36734 [Homo sapiens]
Length = 560
Score = 29.3 bits (64), Expect = 1.8
Identities = 16/54 (29%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Query: 43 RNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLD 96
R+ N F C++ +F + H T ER R + C KC + S P+ L+
Sbjct: 195 RHTGNNSFKCKECGKSFCMLSHLTKHERNHTR--VNCYKCEECGKAFSVPSKLN 246
>gi|169213622 PREDICTED: similar to hCG36734 [Homo sapiens]
Length = 560
Score = 29.3 bits (64), Expect = 1.8
Identities = 16/54 (29%), Positives = 25/54 (46%), Gaps = 2/54 (3%)
Query: 43 RNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKSCPTNLD 96
R+ N F C++ +F + H T ER R + C KC + S P+ L+
Sbjct: 195 RHTGNNSFKCKECGKSFCMLSHLTKHERNHTR--VNCYKCEECGKAFSVPSKLN 246
>gi|54792150 zinc finger protein 473 [Homo sapiens]
Length = 871
Score = 29.3 bits (64), Expect = 1.8
Identities = 13/44 (29%), Positives = 20/44 (45%)
Query: 39 KHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKC 82
+H K + D +NC + F I H T ++ R+ C KC
Sbjct: 309 EHQKTHTDSKSYNCNECGKAFTRIFHLTRHQKIHTRKRYECSKC 352
Score = 26.9 bits (58), Expect = 8.8
Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 4/47 (8%)
Query: 43 RNPDKN--CFNCEKLENNFDDIKHTTLGERGALR--EAMRCLKCADA 85
+NP++ CF C K E F K+ T ER R + C +C A
Sbjct: 553 QNPEQKEKCFKCNKCEKTFSCSKYLTQHERIHTRGVKPFECDQCGKA 599
>gi|54792148 zinc finger protein 473 [Homo sapiens]
Length = 871
Score = 29.3 bits (64), Expect = 1.8
Identities = 13/44 (29%), Positives = 20/44 (45%)
Query: 39 KHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKC 82
+H K + D +NC + F I H T ++ R+ C KC
Sbjct: 309 EHQKTHTDSKSYNCNECGKAFTRIFHLTRHQKIHTRKRYECSKC 352
Score = 26.9 bits (58), Expect = 8.8
Identities = 16/47 (34%), Positives = 22/47 (46%), Gaps = 4/47 (8%)
Query: 43 RNPDKN--CFNCEKLENNFDDIKHTTLGERGALR--EAMRCLKCADA 85
+NP++ CF C K E F K+ T ER R + C +C A
Sbjct: 553 QNPEQKEKCFKCNKCEKTFSCSKYLTQHERIHTRGVKPFECDQCGKA 599
>gi|226371655 zinc finger family member 674 isoform 2 [Homo sapiens]
Length = 575
Score = 28.9 bits (63), Expect = 2.3
Identities = 13/47 (27%), Positives = 22/47 (46%), Gaps = 5/47 (10%)
Query: 29 CSTSAKKLDKK-----HWKRNPDKNCFNCEKLENNFDDIKHTTLGER 70
CS K D+K HW+ + +N + C K +F H ++ +R
Sbjct: 353 CSEHGKASDEKPSPTKHWRTHTKENIYECSKCGKSFRGKSHLSVHQR 399
>gi|89994742 zinc finger family member 674 isoform 1 [Homo sapiens]
Length = 581
Score = 28.9 bits (63), Expect = 2.3
Identities = 13/47 (27%), Positives = 22/47 (46%), Gaps = 5/47 (10%)
Query: 29 CSTSAKKLDKK-----HWKRNPDKNCFNCEKLENNFDDIKHTTLGER 70
CS K D+K HW+ + +N + C K +F H ++ +R
Sbjct: 359 CSEHGKASDEKPSPTKHWRTHTKENIYECSKCGKSFRGKSHLSVHQR 405
>gi|212549782 caspase 8 associated protein 2 [Homo sapiens]
Length = 1982
Score = 28.9 bits (63), Expect = 2.3
Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 7/65 (10%)
Query: 2 APVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKH------WKRNPDKN-CFNCEK 54
AP ++KD + +++ + + AT S SAK + KK W RN D+ C+K
Sbjct: 1884 APPVTKDPSSLKATPGIKDSSAALATSTSLSAKNVIKKKGEIIILWTRNDDREILLECQK 1943
Query: 55 LENNF 59
+F
Sbjct: 1944 RGPSF 1948
>gi|6912288 caspase 8 associated protein 2 [Homo sapiens]
Length = 1982
Score = 28.9 bits (63), Expect = 2.3
Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 7/65 (10%)
Query: 2 APVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKH------WKRNPDKN-CFNCEK 54
AP ++KD + +++ + + AT S SAK + KK W RN D+ C+K
Sbjct: 1884 APPVTKDPSSLKATPGIKDSSAALATSTSLSAKNVIKKKGEIIILWTRNDDREILLECQK 1943
Query: 55 LENNF 59
+F
Sbjct: 1944 RGPSF 1948
>gi|212549532 caspase 8 associated protein 2 [Homo sapiens]
Length = 1982
Score = 28.9 bits (63), Expect = 2.3
Identities = 19/65 (29%), Positives = 31/65 (47%), Gaps = 7/65 (10%)
Query: 2 APVLSKDSADIESILALNPRTQTHATLCSTSAKKLDKKH------WKRNPDKN-CFNCEK 54
AP ++KD + +++ + + AT S SAK + KK W RN D+ C+K
Sbjct: 1884 APPVTKDPSSLKATPGIKDSSAALATSTSLSAKNVIKKKGEIIILWTRNDDREILLECQK 1943
Query: 55 LENNF 59
+F
Sbjct: 1944 RGPSF 1948
>gi|194097407 zinc finger protein 680 isoform 1 [Homo sapiens]
Length = 530
Score = 28.1 bits (61), Expect = 4.0
Identities = 20/67 (29%), Positives = 28/67 (41%), Gaps = 6/67 (8%)
Query: 22 TQTHATLCSTSAKKLDK-----KHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALRE- 75
TQ+ C K K H KRN K F C++ +F + H T R RE
Sbjct: 149 TQSKIFQCDKYVKVFHKFSNSNSHKKRNTGKKVFKCKECGKSFCMLSHLTQHIRIHTREN 208
Query: 76 AMRCLKC 82
+ +C +C
Sbjct: 209 SYKCEEC 215
>gi|28376656 zinc finger, X-linked, duplicated B [Homo sapiens]
Length = 803
Score = 28.1 bits (61), Expect = 4.0
Identities = 16/53 (30%), Positives = 25/53 (47%), Gaps = 1/53 (1%)
Query: 38 KKHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKS 90
K H K + +N F CE E +F + +R E R +CA + C+K+
Sbjct: 352 KAHMKGHEQENSFKCEVCEESFPTQAKLSAHQRSHF-EPERPYQCAFSGCKKT 403
>gi|118498359 ribosomal L1 domain containing 1 [Homo sapiens]
Length = 490
Score = 27.7 bits (60), Expect = 5.2
Identities = 15/53 (28%), Positives = 25/53 (47%)
Query: 7 KDSADIESILALNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNF 59
+DSA A T T T+ K+LDK+ ++ D +C+ +NN+
Sbjct: 2 EDSASASLSSAAATGTSTSTPAAPTARKQLDKEQVRKAVDALLTHCKSRKNNY 54
>gi|20336246 proprotein convertase subtilisin/kexin type 5
preproprotein [Homo sapiens]
Length = 913
Score = 26.9 bits (58), Expect = 8.8
Identities = 22/86 (25%), Positives = 31/86 (36%), Gaps = 17/86 (19%)
Query: 18 LNPRTQTHATLCSTSAKKLDKKHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAM 77
LN T + T C + + KK+ R +NC C + N T G +
Sbjct: 713 LNEETNSCVTHCPDGSYQDTKKNLCRKCSENCKTCTEFHN-------CTECRDGLSLQGS 765
Query: 78 RC-LKCADA---------PCQKSCPT 93
RC + C D PC + C T
Sbjct: 766 RCSVSCEDGRYFNGQDCQPCHRFCAT 791
>gi|28274709 zinc finger, X-linked, duplicated A [Homo sapiens]
Length = 799
Score = 26.9 bits (58), Expect = 8.8
Identities = 16/53 (30%), Positives = 24/53 (45%), Gaps = 1/53 (1%)
Query: 38 KKHWKRNPDKNCFNCEKLENNFDDIKHTTLGERGALREAMRCLKCADAPCQKS 90
K H K + +N F CE E +F +R E R +CA + C+K+
Sbjct: 348 KAHMKGHEQENSFKCEVCEESFPTQAKLGAHQRSHF-EPERPYQCAFSGCKKT 399
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.133 0.414
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 6,688,629
Number of Sequences: 37866
Number of extensions: 282916
Number of successful extensions: 686
Number of sequences better than 10.0: 21
Number of HSP's better than 10.0 without gapping: 7
Number of HSP's successfully gapped in prelim test: 14
Number of HSP's that attempted gapping in prelim test: 671
Number of HSP's gapped (non-prelim): 29
length of query: 173
length of database: 18,247,518
effective HSP length: 95
effective length of query: 78
effective length of database: 14,650,248
effective search space: 1142719344
effective search space used: 1142719344
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 58 (26.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.