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Search of human proteins with 237681173
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]
(472 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens] 939 0.0
gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens] 939 0.0
gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens] 939 0.0
gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens] 939 0.0
gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens] 939 0.0
gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens] 855 0.0
gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens] 277 1e-74
gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens] 133 4e-31
gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens] 133 4e-31
gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens] 130 3e-30
gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens] 129 4e-30
gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens] 128 1e-29
gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo sa... 119 8e-27
gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens] 117 3e-26
gi|13540517 endothelial differentiation, sphingolipid G-protein-... 116 5e-26
gi|4885295 G protein-coupled receptor 12 [Homo sapiens] 115 1e-25
gi|4885325 G protein-coupled receptor 3 [Homo sapiens] 108 1e-23
gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens] 104 2e-22
gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens] 104 2e-22
gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens] 104 2e-22
gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens] 104 2e-22
gi|134244587 endothelial differentiation, sphingolipid G-protein... 103 3e-22
gi|4885341 G protein-coupled receptor 6 [Homo sapiens] 103 3e-22
gi|4505127 melanocortin 2 receptor [Homo sapiens] 100 4e-21
gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens] 97 4e-20
gi|5174535 melanocortin 5 receptor [Homo sapiens] 96 9e-20
gi|119508433 melanocortin 4 receptor [Homo sapiens] 94 3e-19
gi|170671732 melanocortin 3 receptor [Homo sapiens] 94 3e-19
gi|4501951 adenosine A2b receptor [Homo sapiens] 94 3e-19
gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens] 94 3e-19
>gi|237681179 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 939 bits (2428), Expect = 0.0
Identities = 472/472 (100%), Positives = 472/472 (100%)
Query: 1 MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE 60
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
Sbjct: 1 MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE 60
Query: 61 KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 120
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
Sbjct: 61 KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 120
Query: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
Sbjct: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
Query: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
Sbjct: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
Query: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 300
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 300
Query: 301 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 360
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
Sbjct: 301 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 360
Query: 361 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 420
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
Sbjct: 361 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 420
Query: 421 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 472
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
Sbjct: 421 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 472
>gi|237681175 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 939 bits (2428), Expect = 0.0
Identities = 472/472 (100%), Positives = 472/472 (100%)
Query: 1 MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE 60
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
Sbjct: 1 MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE 60
Query: 61 KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 120
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
Sbjct: 61 KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 120
Query: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
Sbjct: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
Query: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
Sbjct: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
Query: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 300
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 300
Query: 301 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 360
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
Sbjct: 301 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 360
Query: 361 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 420
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
Sbjct: 361 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 420
Query: 421 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 472
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
Sbjct: 421 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 472
>gi|237681173 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 939 bits (2428), Expect = 0.0
Identities = 472/472 (100%), Positives = 472/472 (100%)
Query: 1 MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE 60
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
Sbjct: 1 MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE 60
Query: 61 KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 120
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
Sbjct: 61 KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 120
Query: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
Sbjct: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
Query: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
Sbjct: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
Query: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 300
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 300
Query: 301 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 360
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
Sbjct: 301 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 360
Query: 361 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 420
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
Sbjct: 361 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 420
Query: 421 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 472
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
Sbjct: 421 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 472
>gi|237681067 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 939 bits (2428), Expect = 0.0
Identities = 472/472 (100%), Positives = 472/472 (100%)
Query: 1 MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE 60
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
Sbjct: 1 MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE 60
Query: 61 KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 120
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
Sbjct: 61 KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 120
Query: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
Sbjct: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
Query: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
Sbjct: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
Query: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 300
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 300
Query: 301 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 360
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
Sbjct: 301 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 360
Query: 361 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 420
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
Sbjct: 361 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 420
Query: 421 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 472
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
Sbjct: 421 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 472
>gi|38683844 cannabinoid receptor 1 isoform a [Homo sapiens]
Length = 472
Score = 939 bits (2428), Expect = 0.0
Identities = 472/472 (100%), Positives = 472/472 (100%)
Query: 1 MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE 60
MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE
Sbjct: 1 MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE 60
Query: 61 KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 120
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
Sbjct: 61 KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 120
Query: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
Sbjct: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
Query: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
Sbjct: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
Query: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 300
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
Sbjct: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 300
Query: 301 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 360
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
Sbjct: 301 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 360
Query: 361 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 420
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
Sbjct: 361 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 420
Query: 421 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 472
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
Sbjct: 421 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 472
>gi|237681065 cannabinoid receptor 1 isoform b [Homo sapiens]
Length = 439
Score = 855 bits (2208), Expect = 0.0
Identities = 439/472 (93%), Positives = 439/472 (93%), Gaps = 33/472 (6%)
Query: 1 MKSILDGLADTTFRTITTDLLYVGSNDIQYEDIKGDMASKLGYFPQKFPLTSFRGSPFQE 60
MKSILDGLADTTFRTITTDLL GSPFQE
Sbjct: 1 MKSILDGLADTTFRTITTDLL---------------------------------GSPFQE 27
Query: 61 KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 120
KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA
Sbjct: 28 KMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLAIA 87
Query: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF
Sbjct: 88 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 147
Query: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM
Sbjct: 148 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 207
Query: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 300
WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK
Sbjct: 208 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYILWK 267
Query: 301 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 360
AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL
Sbjct: 268 AHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGPLL 327
Query: 361 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 420
AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ
Sbjct: 328 AIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGTAQ 387
Query: 421 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 472
PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL
Sbjct: 388 PLDNSMGDSDCLHKHANNAASVHRAAESCIKSTVKIAKVTMSVSTDTSAEAL 439
>gi|4502929 cannabinoid receptor 2 (macrophage) [Homo sapiens]
Length = 360
Score = 277 bits (709), Expect = 1e-74
Identities = 142/298 (47%), Positives = 196/298 (65%), Gaps = 15/298 (5%)
Query: 108 FMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGS 167
+M+L+ Q+ A+AVL LG + LEN+ VL +IL S LR +PSY FIGSLA AD L S
Sbjct: 25 YMILSGPQKTAVAVLCTLLGLLSALENVAVLYLILSSHQLRRKPSYLFIGSLAGADFLAS 84
Query: 168 VIFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRI 227
V+F SF++FHVFH DS+ VFL K+G VT +FTASVGSL LTAIDRY+ + P +YK +
Sbjct: 85 VVFACSFVNFHVFHGVDSKAVFLLKIGSVTMTFTASVGSLLLTAIDRYLCLRYPPSYKAL 144
Query: 228 VTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLL 287
+TR +A+V +MW ++ +++ LPL+GW C CS++FP I YL+ W+ + L
Sbjct: 145 LTRGRALVTLGIMWVLSALVSYLPLMGWTC--CPRPCSELFPLIPNDYLLSWLLFIAFLF 202
Query: 288 LFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVL 347
I+Y Y ++LWKAH H + S QV + R+D+RLAKTL L
Sbjct: 203 SGIIYTYGHVLWKAHQHVASL-------------SGHQDRQVPGMARMRLDVRLAKTLGL 249
Query: 348 ILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLR 405
+L VL+ICW P+LA+M + + ++ +K FAFCSMLCL+NS VNP+IYALRS ++R
Sbjct: 250 VLAVLLICWFPVLALMAHSLATTLSDQVKKAFAFCSMLCLINSMVNPVIYALRSGEIR 307
>gi|16950638 lysophosphatidic acid receptor 1 [Homo sapiens]
Length = 364
Score = 133 bits (334), Expect = 4e-31
Identities = 103/369 (27%), Positives = 172/369 (46%), Gaps = 41/369 (11%)
Query: 59 QEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLA 118
Q + TA + PQ FYN+S++ F E N +L
Sbjct: 13 QPQFTAMNEPQC----------FYNESIAFFYNRSGKHLATE----------WNTVSKLV 52
Query: 119 IAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFH 178
+ L +T+ F +L NLLV+ I +R P Y+ + +LA AD + + Y +
Sbjct: 53 MG-LGITVCIFIMLANLLVMVAIYVNRRFHF-PIYYLMANLAAADFFAGLAYFYLMFNTG 110
Query: 179 VFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFC 238
R+ + + +L + G + S TASV +L AI+R+I++ R + R+ R + VV
Sbjct: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNR-RVVVVIV 169
Query: 239 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298
++WT+AIV+ +P +GWNC CS++ P ++YL+FW V + +V Y +I
Sbjct: 170 VIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIF 229
Query: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
+RM + H+S + + T + L KT+V++L IICW P
Sbjct: 230 GYVRQRTMRMSR---------HSSGPRRNRDTM-------MSLLKTVVIVLGAFIICWTP 273
Query: 359 LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGT 418
L +++ DV ++ F +L NS +NPIIY+ R K++ FR + C+ +
Sbjct: 274 GLVLLLLDVCCPQCDVL-AYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQIL-CCQRS 331
Query: 419 AQPLDNSMG 427
P + G
Sbjct: 332 ENPTGPTEG 340
>gi|16950636 lysophosphatidic acid receptor 1 [Homo sapiens]
Length = 364
Score = 133 bits (334), Expect = 4e-31
Identities = 103/369 (27%), Positives = 172/369 (46%), Gaps = 41/369 (11%)
Query: 59 QEKMTAGDNPQLVPADQVNITEFYNKSLSSFKENEENIQCGENFMDIECFMVLNPSQQLA 118
Q + TA + PQ FYN+S++ F E N +L
Sbjct: 13 QPQFTAMNEPQC----------FYNESIAFFYNRSGKHLATE----------WNTVSKLV 52
Query: 119 IAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFH 178
+ L +T+ F +L NLLV+ I +R P Y+ + +LA AD + + Y +
Sbjct: 53 MG-LGITVCIFIMLANLLVMVAIYVNRRFHF-PIYYLMANLAAADFFAGLAYFYLMFNTG 110
Query: 179 VFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFC 238
R+ + + +L + G + S TASV +L AI+R+I++ R + R+ R + VV
Sbjct: 111 PNTRRLTVSTWLLRQGLIDTSLTASVANLLAIAIERHITVFRMQLHTRMSNR-RVVVVIV 169
Query: 239 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298
++WT+AIV+ +P +GWNC CS++ P ++YL+FW V + +V Y +I
Sbjct: 170 VIWTMAIVMGAIPSVGWNCICDIENCSNMAPLYSDSYLVFWAIFNLVTFVVMVVLYAHIF 229
Query: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
+RM + H+S + + T + L KT+V++L IICW P
Sbjct: 230 GYVRQRTMRMSR---------HSSGPRRNRDTM-------MSLLKTVVIVLGAFIICWTP 273
Query: 359 LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCEGT 418
L +++ DV ++ F +L NS +NPIIY+ R K++ FR + C+ +
Sbjct: 274 GLVLLLLDVCCPQCDVL-AYEKFFLLLAEFNSAMNPIIYSYRDKEMSATFRQIL-CCQRS 331
Query: 419 AQPLDNSMG 427
P + G
Sbjct: 332 ENPTGPTEG 340
>gi|13027636 sphingosine-1-phosphate receptor 1 [Homo sapiens]
Length = 382
Score = 130 bits (327), Expect = 3e-30
Identities = 91/300 (30%), Positives = 155/300 (51%), Gaps = 21/300 (7%)
Query: 120 AVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHV 179
+V+ + + F +LEN+ VL I ++ RP Y+FIG+LA++DLL V + + +
Sbjct: 49 SVVFILICCFIILENIFVLLTIWKTKKFH-RPMYYFIGNLALSDLLAGVAYTANLLLSGA 107
Query: 180 FHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVT-RPKAVVAFC 238
K + + + G + + +ASV SL AI+RYI++ + + R +++ C
Sbjct: 108 TTYKLTPAQWFLREGSMFVALSASVFSLLAIAIERYITMLKMKLHNGSNNFRLFLLISAC 167
Query: 239 LMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYIL 298
W I++++ LP++GWNC S CS + P + Y++F V ++LLL IV Y I
Sbjct: 168 --WVISLILGGLPIMGWNCISALSSCSTVLPLYHKHYILFCTTVFTLLLLSIVILYCRIY 225
Query: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
+ + R+ R K+I + K + L KT++++L V I CW P
Sbjct: 226 SLVRTRSRRLTFR---KNISKASRSSEK-----------SLALLKTVIIVLSVFIACWAP 271
Query: 359 LLAIMVYDVFGKMNKLIKTVF--AFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSCE 416
L +++ DV K+ K +F + +L +LNS NPIIY L +K++R AF + C+
Sbjct: 272 LFILLLLDVGCKV-KTCDILFRAEYFLVLAVLNSGTNPIIYTLTNKEMRRAFIRIMSCCK 330
>gi|6912348 lysophosphatidic acid receptor 3 [Homo sapiens]
Length = 353
Score = 129 bits (325), Expect = 4e-30
Identities = 80/297 (26%), Positives = 149/297 (50%), Gaps = 26/297 (8%)
Query: 121 VLSLTLGTFTVL----ENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFID 176
V+ L +GTF L N LV+ ++ +R P Y+ + +LA AD + +V+ +
Sbjct: 31 VIVLCVGTFFCLFIFFSNSLVIAAVIKNRKFHF-PFYYLLANLAAADFFAGIAYVFLMFN 89
Query: 177 FHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236
+ + N + + G + +S TAS+ +L + A++R++SI R + + T+ + +
Sbjct: 90 TGPVSKTLTVNRWFLRQGLLDSSLTASLTNLLVIAVERHMSIMRMRVHSNL-TKKRVTLL 148
Query: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWI--GVTSVLLLFIVYAY 294
L+W IAI + +P LGWNC S CS + P +YL+FW + + L++ +VY
Sbjct: 149 ILLVWAIAIFMGAVPTLGWNCLCNISACSSLAPIYSRSYLVFWTVSNLMAFLIMVVVYLR 208
Query: 295 MYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLII 354
+Y+ K +K+ ++ G + + R ++L KT++ +L ++
Sbjct: 209 IYVYVK-------------RKTNVLSPHTSGSI-----SRRRTPMKLMKTVMTVLGAFVV 250
Query: 355 CWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM 411
CW P L +++ D ++ V + +L LLNS VNPIIY+ + +D+ + M
Sbjct: 251 CWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDMYGTMKKM 307
>gi|38788193 sphingosine-1-phosphate receptor 3 [Homo sapiens]
Length = 378
Score = 128 bits (322), Expect = 1e-29
Identities = 98/346 (28%), Positives = 159/346 (45%), Gaps = 41/346 (11%)
Query: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
VL L + +F VLENL+VL I + R Y FIG+LA+ DLL + + + +
Sbjct: 44 VLFLVICSFIVLENLMVLIAIWKNNKFHNR-MYFFIGNLALCDLLAGIAYKVNILMSGKK 102
Query: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
S V+ + G + + AS SL AI+R++++ + Y R + + +
Sbjct: 103 TFSLSPTVWFLREGSMFVALGASTCSLLAIAIERHLTMIKMRPYDAN-KRHRVFLLIGMC 161
Query: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIV--YAYMYIL 298
W IA + LP+LGWNC CS I P + Y+ F I + + +L+ IV YA +Y L
Sbjct: 162 WLIAFTLGALPILGWNCLHNLPDCSTILPLYSKKYIAFCISIFTAILVTIVILYARIYFL 221
Query: 299 WKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICWGP 358
K+ S +V + + + L +T+V+++ V I CW P
Sbjct: 222 VKSSSR-----------------------KVANHNNSERSMALLRTVVIVVSVFIACWSP 258
Query: 359 LLAIMVYDVFGKMNKL-IKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFPSC-- 415
L + + DV ++ I + +L +LNS +NP+IY L SK++R AF + +C
Sbjct: 259 LFILFLIDVACRVQACPILFKAQWFIVLAVLNSAMNPVIYTLASKEMRRAFFRLVCNCLV 318
Query: 416 ---EGTAQPLDNSMGDSDCLHKHANNAAS--------VHRAAESCI 450
A P+ ++ S +NN++ H A SCI
Sbjct: 319 RGRGARASPIQPALDPSRSKSSSSNNSSHSPKVKEDLPHTAPSSCI 364
>gi|4503459 sphingosine-1-phosphate receptor 4 precursor [Homo
sapiens]
Length = 384
Score = 119 bits (297), Expect = 8e-27
Identities = 96/330 (29%), Positives = 159/330 (48%), Gaps = 34/330 (10%)
Query: 118 AIAVLSLTLGTFTVLENLLVLCVIL-HSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFID 176
A+ LS+ VLENLLVL I H RS R Y+ + ++ ++DLL ++ + +
Sbjct: 48 ALRGLSVAASCLVVLENLLVLAAITSHMRSRRW--VYYCLVNITLSDLLTGAAYLANVLL 105
Query: 177 FHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236
+ + + + G + + AS SL TA +R+ ++ RP+A +
Sbjct: 106 SGARTFRLAPAQWFLREGLLFTALAASTFSLLFTAGERFATMVRPVAESGATKTSRVYGF 165
Query: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMY 296
L W +A ++ +LPLLGWNC CS + P + Y++F + + + +L I+ Y
Sbjct: 166 IGLCWLLAALLGMLPLLGWNCLCAFDRCSSLLPLYSKRYILFCLVIFAGVLATIMGLYGA 225
Query: 297 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 356
I R++Q QK+ RP R RL KT+++IL+ ++CW
Sbjct: 226 IF--------RLVQASGQKA-------------PRPAARRKARRLLKTVLMILLAFLVCW 264
Query: 357 GPLLAIMVYDVFGK---MNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSMFP 413
GPL +++ DVFG + ++ + + L +LNS VNPIIY+ RS+++ A S
Sbjct: 265 GPLFGLLLADVFGSNLWAQEYLRGM-DWILALAVLNSAVNPIIYSFRSREVCRAVLSFL- 322
Query: 414 SCEGTAQPLDNSMGDSDCLHK--HANNAAS 441
C G + G DCL + A++ AS
Sbjct: 323 -CCGCLRL--GMRGPGDCLARAVEAHSGAS 349
>gi|7305013 lysophosphatidic acid receptor 2 [Homo sapiens]
Length = 351
Score = 117 bits (292), Expect = 3e-26
Identities = 81/299 (27%), Positives = 137/299 (45%), Gaps = 22/299 (7%)
Query: 115 QQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSF 174
+ + + L LT+ +L NLLV+ I +R +P Y+ +G+LA ADL V Y F
Sbjct: 31 KDVVVVALGLTVSVLVLLTNLLVIAAIASNRRFH-QPIYYLLGNLAAADLFAGV--AYLF 87
Query: 175 IDFHVFHR--KDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 232
+ FH R + S + + G + S TASV +L A++R+ S+ + R+ R +
Sbjct: 88 LMFHTGPRTARLSLEGWFLRQGLLDTSLTASVATLLAIAVERHRSVMAVQLHSRL-PRGR 146
Query: 233 AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 292
V+ +W A+ + +LP W+C CS + P + +YL W + ++ L +V
Sbjct: 147 VVMLIVGVWVAALGLGLLPAHSWHCLCALDRCSRMAPLLSRSYLAVWALSSLLVFLLMVA 206
Query: 293 AYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVL 352
Y I + RM + H S P + L KT+V+IL
Sbjct: 207 VYTRIFFYVRRRVQRMAE---------HVS-------CHPRYRETTLSLVKTVVIILGAF 250
Query: 353 IICWGPLLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHAFRSM 411
++CW P +++ D G + + V + +L NS VN +Y+ R ++R FR +
Sbjct: 251 VVCWTPGQVVLLLDGLGCESCNVLAVEKYFLLLAEANSLVNAAVYSCRDAEMRRTFRRL 309
>gi|13540517 endothelial differentiation, sphingolipid
G-protein-coupled receptor, 8 [Homo sapiens]
Length = 398
Score = 116 bits (290), Expect = 5e-26
Identities = 87/293 (29%), Positives = 144/293 (49%), Gaps = 17/293 (5%)
Query: 118 AIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDF 177
A AV+ L + F VLENL VL V+ P + +GSL ++DLL + + +
Sbjct: 38 ADAVVCLAVCAFIVLENLAVLLVLGRHPRFHA-PMFLLLGSLTLSDLLAGAAYAANILLS 96
Query: 178 HVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAF 237
K S ++ + GGV + TASV SL A++R +++ R + +R + +
Sbjct: 97 GPLTLKLSPALWFAREGGVFVALTASVLSLLAIALERSLTMARR-GPAPVSSRGRTLAMA 155
Query: 238 CLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMYI 297
W +++++ +LP LGWNC CS + P + Y++F + +L I Y I
Sbjct: 156 AAAWGVSLLLGLLPALGWNCLGRLDACSTVLPLYAKAYVLFCVLAFVGILAAICALYARI 215
Query: 298 LWKAHSHAVRMIQR-GTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 356
+ ++A R+ R GT + TS TR + + L +TL ++L+ + CW
Sbjct: 216 YCQVRANARRLPARPGTAGT----TS-------TRARRKPRSLALLRTLSVVLLAFVACW 264
Query: 357 GPLLAIMVYDVF--GKMNKLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRHA 407
GPL +++ DV + ++ F L + NS +NPIIY L ++DLRHA
Sbjct: 265 GPLFLLLLLDVACPARTCPVLLQADPFLG-LAMANSLLNPIIYTLTNRDLRHA 316
>gi|4885295 G protein-coupled receptor 12 [Homo sapiens]
Length = 334
Score = 115 bits (287), Expect = 1e-25
Identities = 82/304 (26%), Positives = 146/304 (48%), Gaps = 39/304 (12%)
Query: 109 MVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSV 168
+V+NP ++ T GT EN +V+ +I H+ SLR P + IGSLA+ADLL +
Sbjct: 42 LVVNPWD-----IVLCTSGTLISCENAIVVLIIFHNPSLRA-PMFLLIGSLALADLLAGI 95
Query: 169 IFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIV 228
+ +F+ ++ + ++ L +G + ASF+ASV SL +DRY+S++ L Y
Sbjct: 96 GLITNFVFAYLLQSEATK---LVTIGLIVASFSASVCSLLAITVDRYLSLYYALTYHSER 152
Query: 229 TRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLL 288
T V ++W +I + +LP++GWNC + +S CS + P + + S L +
Sbjct: 153 TVTFTYVMLVMLWGTSICLGLLPVMGWNCLRDESTCSVVRPLTKNNAAILSV---SFLFM 209
Query: 289 FIVYAYMYI----LWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKT 344
F + +YI + H+H + + S + T + T
Sbjct: 210 FALMLQLYIQICKIVMRHAHQIALQHHFLATSHYVTTRKG-----------------VST 252
Query: 345 LVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSML-CLLNSTVNPIIYALRSKD 403
L +IL CW P +Y + + +++ + ++L NS +NP+IYA R+++
Sbjct: 253 LAIILGTFAACWMP---FTLYSLIA--DYTYPSIYTYATLLPATYNSIINPVIYAFRNQE 307
Query: 404 LRHA 407
++ A
Sbjct: 308 IQKA 311
>gi|4885325 G protein-coupled receptor 3 [Homo sapiens]
Length = 330
Score = 108 bits (270), Expect = 1e-23
Identities = 87/311 (27%), Positives = 148/311 (47%), Gaps = 29/311 (9%)
Query: 113 PSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVY 172
PS + VL ++ GT EN LV+ +I+ + + R P + +GSLAVADLL + V
Sbjct: 38 PSPKAWDVVLCIS-GTLVSCENALVVAIIVGTPAFRA-PMFLLVGSLAVADLLAGLGLVL 95
Query: 173 SFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 232
F S + L +G + +FTAS+GSL +DRY+S++ L Y T +
Sbjct: 96 HFAAVFCI---GSAEMSLVLVGVLAMAFTASIGSLLAITVDRYLSLYNALTYYSETTVTR 152
Query: 233 AVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 292
V L+W A+ + +LP+L WNC + C ++P + + +L V + F+V+
Sbjct: 153 TYVMLALVWGGALGLGLLPVLAWNCLDGLTTCGVVYP-LSKNHL-----VVLAIAFFMVF 206
Query: 293 AYMYILWKAHSHAVRMIQRGTQK-SIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVV 351
I+ + ++ R++ R Q+ ++ H TR A TL ++L
Sbjct: 207 G---IMLQLYAQICRIVCRHAQQIALQRHLLPASHYVATRKGIA--------TLAVVLGA 255
Query: 352 LIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSML-CLLNSTVNPIIYALRSKDLRHAFRS 410
CW L VY + G + ++ + ++L NS +NPIIYA R++D++ +
Sbjct: 256 FAACW---LPFTVYCLLGDAHS--PPLYTYLTLLPATYNSMINPIIYAFRNQDVQKVLWA 310
Query: 411 MFPSCEGTAQP 421
+ C + P
Sbjct: 311 VCCCCSSSKIP 321
>gi|111118990 alpha-1A-adrenergic receptor isoform 4 [Homo sapiens]
Length = 455
Score = 104 bits (259), Expect = 2e-22
Identities = 90/329 (27%), Positives = 151/329 (45%), Gaps = 37/329 (11%)
Query: 111 LNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLL-GSVI 169
+N S+ + + V+ L F VL N+LV+ + R L Y+ + +LAVADLL S +
Sbjct: 21 VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIV-NLAVADLLLTSTV 79
Query: 170 FVYSFIDFHVFHRKDSRNVFLFKLGGVTA-SFTASVGSLFLTAIDRYISIHRPLAYKRIV 228
+S I F V VF V TAS+ L + +IDRYI + PL Y IV
Sbjct: 80 LPFSAI-FEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIV 138
Query: 229 TRPKAVVAFCLMWTIAIVIAVLPLLGWN---------CEKLQSVCSDIFPHIDETYLMFW 279
T+ + ++A +W +++VI++ PL GW C+ + +F + YL
Sbjct: 139 TQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYL--- 195
Query: 280 IGVTSVLLLFIVYAYMYILWKAHSHAVRMIQR-----GTQKSIIIHTSE---DGKVQVTR 331
+ ++ ++Y +Y++ K S ++ + Q ++ IH G +
Sbjct: 196 ----PLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASA 251
Query: 332 PDQARMDIRL---------AKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFC 382
+ +RL AKTL +++ ++CW P +M F K +TVF
Sbjct: 252 KTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIV 311
Query: 383 SMLCLLNSTVNPIIYALRSKDLRHAFRSM 411
L LNS +NPIIY S++ + AF+++
Sbjct: 312 FWLGYLNSCINPIIYPCSSQEFKKAFQNV 340
>gi|111118992 alpha-1A-adrenergic receptor isoform 1 [Homo sapiens]
Length = 466
Score = 104 bits (259), Expect = 2e-22
Identities = 90/329 (27%), Positives = 151/329 (45%), Gaps = 37/329 (11%)
Query: 111 LNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLL-GSVI 169
+N S+ + + V+ L F VL N+LV+ + R L Y+ + +LAVADLL S +
Sbjct: 21 VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIV-NLAVADLLLTSTV 79
Query: 170 FVYSFIDFHVFHRKDSRNVFLFKLGGVTA-SFTASVGSLFLTAIDRYISIHRPLAYKRIV 228
+S I F V VF V TAS+ L + +IDRYI + PL Y IV
Sbjct: 80 LPFSAI-FEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIV 138
Query: 229 TRPKAVVAFCLMWTIAIVIAVLPLLGWN---------CEKLQSVCSDIFPHIDETYLMFW 279
T+ + ++A +W +++VI++ PL GW C+ + +F + YL
Sbjct: 139 TQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYL--- 195
Query: 280 IGVTSVLLLFIVYAYMYILWKAHSHAVRMIQR-----GTQKSIIIHTSE---DGKVQVTR 331
+ ++ ++Y +Y++ K S ++ + Q ++ IH G +
Sbjct: 196 ----PLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASA 251
Query: 332 PDQARMDIRL---------AKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFC 382
+ +RL AKTL +++ ++CW P +M F K +TVF
Sbjct: 252 KTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIV 311
Query: 383 SMLCLLNSTVNPIIYALRSKDLRHAFRSM 411
L LNS +NPIIY S++ + AF+++
Sbjct: 312 FWLGYLNSCINPIIYPCSSQEFKKAFQNV 340
>gi|111118986 alpha-1A-adrenergic receptor isoform 2 [Homo sapiens]
Length = 475
Score = 104 bits (259), Expect = 2e-22
Identities = 90/329 (27%), Positives = 151/329 (45%), Gaps = 37/329 (11%)
Query: 111 LNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLL-GSVI 169
+N S+ + + V+ L F VL N+LV+ + R L Y+ + +LAVADLL S +
Sbjct: 21 VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIV-NLAVADLLLTSTV 79
Query: 170 FVYSFIDFHVFHRKDSRNVFLFKLGGVTA-SFTASVGSLFLTAIDRYISIHRPLAYKRIV 228
+S I F V VF V TAS+ L + +IDRYI + PL Y IV
Sbjct: 80 LPFSAI-FEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIV 138
Query: 229 TRPKAVVAFCLMWTIAIVIAVLPLLGWN---------CEKLQSVCSDIFPHIDETYLMFW 279
T+ + ++A +W +++VI++ PL GW C+ + +F + YL
Sbjct: 139 TQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYL--- 195
Query: 280 IGVTSVLLLFIVYAYMYILWKAHSHAVRMIQR-----GTQKSIIIHTSE---DGKVQVTR 331
+ ++ ++Y +Y++ K S ++ + Q ++ IH G +
Sbjct: 196 ----PLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASA 251
Query: 332 PDQARMDIRL---------AKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFC 382
+ +RL AKTL +++ ++CW P +M F K +TVF
Sbjct: 252 KTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIV 311
Query: 383 SMLCLLNSTVNPIIYALRSKDLRHAFRSM 411
L LNS +NPIIY S++ + AF+++
Sbjct: 312 FWLGYLNSCINPIIYPCSSQEFKKAFQNV 340
>gi|111118988 alpha-1A-adrenergic receptor isoform 3 [Homo sapiens]
Length = 429
Score = 104 bits (259), Expect = 2e-22
Identities = 90/329 (27%), Positives = 151/329 (45%), Gaps = 37/329 (11%)
Query: 111 LNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLL-GSVI 169
+N S+ + + V+ L F VL N+LV+ + R L Y+ + +LAVADLL S +
Sbjct: 21 VNISKAILLGVILGGLILFGVLGNILVILSVACHRHLHSVTHYYIV-NLAVADLLLTSTV 79
Query: 170 FVYSFIDFHVFHRKDSRNVFLFKLGGVTA-SFTASVGSLFLTAIDRYISIHRPLAYKRIV 228
+S I F V VF V TAS+ L + +IDRYI + PL Y IV
Sbjct: 80 LPFSAI-FEVLGYWAFGRVFCNIWAAVDVLCCTASIMGLCIISIDRYIGVSYPLRYPTIV 138
Query: 229 TRPKAVVAFCLMWTIAIVIAVLPLLGWN---------CEKLQSVCSDIFPHIDETYLMFW 279
T+ + ++A +W +++VI++ PL GW C+ + +F + YL
Sbjct: 139 TQRRGLMALLCVWALSLVISIGPLFGWRQPAPEDETICQINEEPGYVLFSALGSFYL--- 195
Query: 280 IGVTSVLLLFIVYAYMYILWKAHSHAVRMIQR-----GTQKSIIIHTSE---DGKVQVTR 331
+ ++ ++Y +Y++ K S ++ + Q ++ IH G +
Sbjct: 196 ----PLAIILVMYCRVYVVAKRESRGLKSGLKTDKSDSEQVTLRIHRKNAPAGGSGMASA 251
Query: 332 PDQARMDIRL---------AKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFC 382
+ +RL AKTL +++ ++CW P +M F K +TVF
Sbjct: 252 KTKTHFSVRLLKFSREKKAAKTLGIVVGCFVLCWLPFFLVMPIGSFFPDFKPSETVFKIV 311
Query: 383 SMLCLLNSTVNPIIYALRSKDLRHAFRSM 411
L LNS +NPIIY S++ + AF+++
Sbjct: 312 FWLGYLNSCINPIIYPCSSQEFKKAFQNV 340
>gi|134244587 endothelial differentiation, sphingolipid
G-protein-coupled receptor, 5 [Homo sapiens]
Length = 353
Score = 103 bits (257), Expect = 3e-22
Identities = 84/295 (28%), Positives = 139/295 (47%), Gaps = 33/295 (11%)
Query: 114 SQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYS 173
S+Q+A A + + L V+ENLLVL + + Y F+G+LA +DLL V FV +
Sbjct: 32 SRQVASAFIVI-LCCAIVVENLLVLIAVARNSKFHSA-MYLFLGNLAASDLLAGVAFVAN 89
Query: 174 FIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKA 233
+ + + + + G + +ASV SL AI+R+++I + Y + +
Sbjct: 90 TLLSGSVTLRLTPVQWFAREGSAFITLSASVFSLLAIAIERHVAIAKVKLYGSDKSC-RM 148
Query: 234 VVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYA 293
++ W I++V+ LP+LGWNC CS + P + Y++ + + S++LL IV
Sbjct: 149 LLLIGASWLISLVLGGLPILGWNCLGHLEACSTVLPLYAKHYVLCVVTIFSIILLAIVAL 208
Query: 294 YMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLI 353
Y+ I S M A + L KT+ ++L V I
Sbjct: 209 YVRIYCVVRSSHADM-------------------------AAPQTLALLKTVTIVLGVFI 243
Query: 354 ICWGPLLAIMVYDVFGKMNK---LIKTVFAFCSMLCLLNSTVNPIIYALRSKDLR 405
+CW P +I++ D ++ L K + F + LNS +NP+IY RS+DLR
Sbjct: 244 VCWLPAFSILLLDYACPVHSCPILYKAHYFFA--VSTLNSLLNPVIYTWRSRDLR 296
>gi|4885341 G protein-coupled receptor 6 [Homo sapiens]
Length = 362
Score = 103 bits (257), Expect = 3e-22
Identities = 84/300 (28%), Positives = 138/300 (46%), Gaps = 34/300 (11%)
Query: 121 VLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVF 180
VL GT EN LV+ +I + +LR P + +GSLA ADLL + F+ ++
Sbjct: 77 VLLCVSGTVIAGENALVVALIASTPALRT-PMFVLVGSLATADLLAGCGLILHFVFQYLV 135
Query: 181 HRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAFCLM 240
S V L +G + ASF ASV SL +DRY+S++ L Y T +
Sbjct: 136 ---PSETVSLLTVGFLVASFAASVSSLLAITVDRYLSLYNALTYYSRRTLLGVHLLLAAT 192
Query: 241 WTIAIVIAVLPLLGWNCEKLQSVCSDIFP----HIDETYLMFWIGVTSVLLLFIVYAYMY 296
WT+++ + +LP+LGWNC ++ CS + P H+ F++ +L L++
Sbjct: 193 WTVSLGLGLLPVLGWNCLAERAACSVVRPLARSHVALLSAAFFMVFGIMLHLYV--RICQ 250
Query: 297 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 356
++W+ H+H + + Q H + TR + TL ++L W
Sbjct: 251 VVWR-HAHQIALQQ---------HCLAPPHLAATR--------KGVGTLAVVLGTFGASW 292
Query: 357 GPLLAIMVYDVFGKMNKLIKTVFAFCSML-CLLNSTVNPIIYALRSKDLRHAFRSMFPSC 415
L +Y V G V+ + ++L NS +NPIIYA R+++++ A + C
Sbjct: 293 ---LPFAIYCVVGSHED--PAVYTYATLLPATYNSMINPIIYAFRNQEIQRALWLLLCGC 347
>gi|4505127 melanocortin 2 receptor [Homo sapiens]
Length = 297
Score = 100 bits (248), Expect = 4e-21
Identities = 84/305 (27%), Positives = 133/305 (43%), Gaps = 65/305 (21%)
Query: 125 TLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRKD 184
T+ VLENL+VL + +++L+ P Y FI SLA++D+LGS+ + I +
Sbjct: 33 TISIVGVLENLIVLLAVFKNKNLQA-PMYFFICSLAISDMLGSLYKILENILIIL----- 86
Query: 185 SRNVFLFKLGG-------------VTASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRP 231
RN+ K G S S+ SL + A DRYI+I L Y IVT
Sbjct: 87 -RNMGYLKPRGSFETTADDIIDSLFVLSLLGSIFSLSVIAADRYITIFHALRYHSIVTMR 145
Query: 232 KAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFI- 290
+ VV ++WT + + IF H T + F + ++L+FI
Sbjct: 146 RTVVVLTVIWTFCTGTGITMV--------------IFSHHVPTVITF-TSLFPLMLVFIL 190
Query: 291 -VYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLIL 349
+Y +M++L ++H+ + + R K I TL ++L
Sbjct: 191 CLYVHMFLLARSHTRKISTLPRANMKGAI-------------------------TLTILL 225
Query: 350 VVLIICWGPLLAIMVYDVFGKMN---KLIKTVFAFCSMLCLLNSTVNPIIYALRSKDLRH 406
V I CW P + ++ F N ++F ML + N+ ++P IYA RS +LR
Sbjct: 226 GVFIFCWAPFVLHVLLMTFCPSNPYCACYMSLFQVNGMLIMCNAVIDPFIYAFRSPELRD 285
Query: 407 AFRSM 411
AF+ M
Sbjct: 286 AFKKM 290
>gi|4501959 alpha-1B-adrenergic receptor [Homo sapiens]
Length = 520
Score = 96.7 bits (239), Expect = 4e-20
Identities = 94/327 (28%), Positives = 151/327 (46%), Gaps = 36/327 (11%)
Query: 122 LSLTLGTF---TVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFH 178
+ L LG F ++ N+LV+ + +R LR P+ +FI +LA+ADLL S +
Sbjct: 48 VGLVLGAFILFAIVGNILVILSVACNRHLRT-PTNYFIVNLAMADLLLSFTVLPFSAALE 106
Query: 179 VFHRKDSRNVFLFKLGGVTA-SFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVAF 237
V +F V TAS+ SL +IDRYI + L Y +VTR KA++A
Sbjct: 107 VLGYWVLGRIFCDIWAAVDVLCCTASILSLCAISIDRYIGVRYSLQYPTLVTRRKAILAL 166
Query: 238 CLMWTIAIVIAVLPLLGW-----NCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVY 292
+W ++ VI++ PLLGW N +K V + F + + F+I + +L ++Y
Sbjct: 167 LSVWVLSTVISIGPLLGWKEPAPNDDKECGVTEEPFYALFSSLGSFYIPLAVIL---VMY 223
Query: 293 AYMYI------------LWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQA----- 335
+YI + K S++ + R K+ T K + P +
Sbjct: 224 CRVYIVAKRTTKNLEAGVMKEMSNSKELTLRIHSKNFHEDTLSSTKAKGHNPRSSIAVKL 283
Query: 336 ---RMDIRLAKTLVLILVVLIICWGP-LLAIMVYDVFGKMNKLIKTVFAFCSMLCLLNST 391
+ + AKTL +++ + I+CW P +A+ + +F + K VF L NS
Sbjct: 284 FKFSREKKAAKTLGIVVGMFILCWLPFFIALPLGSLFSTL-KPPDAVFKVVFWLGYFNSC 342
Query: 392 VNPIIYALRSKDLRHAF-RSMFPSCEG 417
+NPIIY SK+ + AF R + C G
Sbjct: 343 LNPIIYPCSSKEFKRAFVRILGCQCRG 369
>gi|5174535 melanocortin 5 receptor [Homo sapiens]
Length = 325
Score = 95.5 bits (236), Expect = 9e-20
Identities = 82/318 (25%), Positives = 143/318 (44%), Gaps = 46/318 (14%)
Query: 112 NPSQQLAIAV-LSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIF 170
+P + + IAV + LTLG ++LEN+LV+ I+ +++L P Y F+ SLAVAD+L S+
Sbjct: 31 SPCEDMGIAVEVFLTLGVISLLENILVIGAIVKNKNLHS-PMYFFVCSLAVADMLVSMSS 89
Query: 171 VYSFIDFHVFHRKDS--RNVFLFKLGGV-----TASFTASVGSLFLTAIDRYISIHRPLA 223
+ I ++ + K + F+ + V S AS+ SL A+DRY++I L
Sbjct: 90 AWETITIYLLNNKHLVIADAFVRHIDNVFDSMICISVVASMCSLLAIAVDRYVTIFYALR 149
Query: 224 YKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETY-LMFWIGV 282
Y I+T ++ +W ++ +L + + TY ++ I +
Sbjct: 150 YHHIMTARRSGAIIAGIWAFCTGCGIVFIL----------------YSESTYVILCLISM 193
Query: 283 TSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLA 342
+L +V Y+++ A +H R+ S TS G V VT
Sbjct: 194 FFAMLFLLVSLYIHMFLLARTHVKRIAALPGASSARQRTSMQGAVTVT------------ 241
Query: 343 KTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFAFCSM---LCLLNSTVNPIIYAL 399
++L V +CW P + + N + +M L + NS ++P+IYA
Sbjct: 242 ----MLLGVFTVCWAPFFLHLTLMLSCPQNLYCSRFMSHFNMYLILIMCNSVMDPLIYAF 297
Query: 400 RSKDLRHAFRSMFPSCEG 417
RS+++R F+ + C G
Sbjct: 298 RSQEMRKTFKEII-CCRG 314
>gi|119508433 melanocortin 4 receptor [Homo sapiens]
Length = 332
Score = 93.6 bits (231), Expect = 3e-19
Identities = 82/322 (25%), Positives = 146/322 (45%), Gaps = 46/322 (14%)
Query: 99 GENFMDIECFMVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGS 158
G+ + D C+ L S ++ + TLG ++LEN+LV+ I +++L P Y FI S
Sbjct: 32 GKGYSDGGCYEQLFVSPEVFV-----TLGVISLLENILVIVAIAKNKNLHS-PMYFFICS 85
Query: 159 LAVADLLGSVIFVYSFIDFHVFHRKDS-RNVFLFKLGGVT-----ASFTASVGSLFLTAI 212
LAVAD+L SV I + + D+ F + V +S AS+ SL A+
Sbjct: 86 LAVADMLVSVSNGSETIVITLLNSTDTDAQSFTVNIDNVIDSVICSSLLASICSLLSIAV 145
Query: 213 DRYISIHRPLAYKRIVTRPKAVVAFCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHID 272
DRY +I L Y I+T + + +W V +L + + SD I
Sbjct: 146 DRYFTIFYALQYHNIMTVKRVGIIISCIWAACTVSGILFI----------IYSDSSAVII 195
Query: 273 ETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRP 332
MF+ T + L+ +Y +M+++ + H + ++ T
Sbjct: 196 CLITMFF---TMLALMASLYVHMFLMARLHIKRIAVLPG------------------TGA 234
Query: 333 DQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNK---LIKTVFAFCSMLCLLN 389
+ +++ A TL +++ V ++CW P +++ + N + F +L + N
Sbjct: 235 IRQGANMKGAITLTILIGVFVVCWAPFFLHLIFYISCPQNPYCVCFMSHFNLYLILIMCN 294
Query: 390 STVNPIIYALRSKDLRHAFRSM 411
S ++P+IYALRS++LR F+ +
Sbjct: 295 SIIDPLIYALRSQELRKTFKEI 316
>gi|170671732 melanocortin 3 receptor [Homo sapiens]
Length = 323
Score = 93.6 bits (231), Expect = 3e-19
Identities = 80/304 (26%), Positives = 136/304 (44%), Gaps = 40/304 (13%)
Query: 124 LTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYSFIDFHVFHRK 183
L+LG ++LEN+LV+ ++ + +L P Y F+ SLAVAD+L SV I + H
Sbjct: 46 LSLGIVSLLENILVILAVVRNGNLHS-PMYFFLCSLAVADMLVSVSNALETIMIAIVHSD 104
Query: 184 --DSRNVFLFKLGGV-----TASFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPKAVVA 236
+ F+ + + S AS+ +L A+DRY++I L Y I+T KA+
Sbjct: 105 YLTFEDQFIQHMDNIFDSMICISLVASICNLLAIAVDRYVTIFYALRYHSIMTVRKALTL 164
Query: 237 FCLMWTIAIVIAVLPLLGWNCEKLQSVCSDIFPHIDETYLMFWIGVTSVLLLFIVYAYMY 296
+W V V+ ++ ++ K+ VC MF+ +LL+ +Y +M+
Sbjct: 165 IVAIWVCCGVCGVVFIV-YSESKMVIVC---------LITMFF---AMMLLMGTLYVHMF 211
Query: 297 ILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQVTRPDQARMDIRLAKTLVLILVVLIICW 356
+ + H + + + H+ G V +T ++L V I CW
Sbjct: 212 LFARLHVKRIAALPPADGVAPQQHSCMKGAVTIT----------------ILLGVFIFCW 255
Query: 357 GPLLAIMVYDVFGKMNKLIKTVFAFCS---MLCLLNSTVNPIIYALRSKDLRHAFRSMFP 413
P +V + N A + +L + NS ++P+IYA RS +LR+ FR +
Sbjct: 256 APFFLHLVLIITCPTNPYCICYTAHFNTYLVLIMCNSVIDPLIYAFRSLELRNTFREILC 315
Query: 414 SCEG 417
C G
Sbjct: 316 GCNG 319
>gi|4501951 adenosine A2b receptor [Homo sapiens]
Length = 332
Score = 93.6 bits (231), Expect = 3e-19
Identities = 87/325 (26%), Positives = 144/325 (44%), Gaps = 43/325 (13%)
Query: 109 MVLNPSQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSV 168
M+L L +A L L + +V N+LV + + +L+ P+ +F+ SLA AD+ +
Sbjct: 1 MLLETQDALYVA-LELVIAALSVAGNVLVCAAVGTANTLQT-PTNYFLVSLAAADVAVGL 58
Query: 169 IFVYSFIDFHVFHRKDSRNVFLFKLGGVTASFTASVGSLFLTAIDRYISIHRPLAYKRIV 228
+ I + D LF V +S+ SL A+DRY++I PL YK +V
Sbjct: 59 FAIPFAITISLGFCTDFYGC-LFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLV 117
Query: 229 TRPKAVVAFCLMWTIAIVIAVLPLLGWN--------------------CEKLQSVCSDIF 268
T +A ++W +A I + P LGWN C ++ + ++
Sbjct: 118 TGTRARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVV 177
Query: 269 PHIDETYLMFWIGVTSVLLLFIVYAYMYILWKAHSHAVRMIQRGTQKSIIIHTSEDGKVQ 328
P Y F+ V LL+ +V +YI K A R +QR ++ H+
Sbjct: 178 PMSYMVYFNFFGCVLPPLLIMLV---IYI--KIFLVACRQLQR---TELMDHSR------ 223
Query: 329 VTRPDQARMDIRLAKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFA--FCSMLC 386
+ +I AK+L +I+ + +CW P+ A+ +F K +A +L
Sbjct: 224 ----TTLQREIHAAKSLAMIVGIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLS 279
Query: 387 LLNSTVNPIIYALRSKDLRHAFRSM 411
NS VNPI+YA R++D R+ F +
Sbjct: 280 HANSVVNPIVYAYRNRDFRYTFHKI 304
>gi|4501957 alpha-1D-adrenergic receptor [Homo sapiens]
Length = 572
Score = 93.6 bits (231), Expect = 3e-19
Identities = 82/328 (25%), Positives = 140/328 (42%), Gaps = 41/328 (12%)
Query: 114 SQQLAIAVLSLTLGTFTVLENLLVLCVILHSRSLRCRPSYHFIGSLAVADLLGSVIFVYS 173
+Q + + V V NLLV+ + +R L+ +Y FI +LAVADLL S +
Sbjct: 94 AQGVGVGVFLAAFILMAVAGNLLVILSVACNRHLQTVTNY-FIVNLAVADLLLSATVLPF 152
Query: 174 FIDFHVFHRKDSRNVFLFKLGGVTA-SFTASVGSLFLTAIDRYISIHRPLAYKRIVTRPK 232
V F V TAS+ SL ++DRY+ + L Y I+T K
Sbjct: 153 SATMEVLGFWAFGRAFCDVWAAVDVLCCTASILSLCTISVDRYVGVRHSLKYPAIMTERK 212
Query: 233 AVVAFCLMWTIAIVIAVLPLLGWN---------CEKLQSVCSDIFPHIDETYLMFWIGVT 283
A L+W +A+V++V PLLGW C + +F + YL
Sbjct: 213 AAAILALLWVVALVVSVGPLLGWKEPVPPDERFCGITEEAGYAVFSSVCSFYL------- 265
Query: 284 SVLLLFIVYAYMYILWKAHSHAVR---MIQRGTQKSIIIH-------TSEDG----KVQV 329
+ ++ ++Y +Y++ ++ + ++ +RG +++ T DG +
Sbjct: 266 PMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKASEVVLRIHCRGAATGADGAHGMRSAK 325
Query: 330 TRPDQARMDIRL---------AKTLVLILVVLIICWGPLLAIMVYDVFGKMNKLIKTVFA 380
++ + +RL AKTL +++ V ++CW P ++ K + VF
Sbjct: 326 GHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLCWFPFFFVLPLGSLFPQLKPSEGVFK 385
Query: 381 FCSMLCLLNSTVNPIIYALRSKDLRHAF 408
L NS VNP+IY S++ + AF
Sbjct: 386 VIFWLGYFNSCVNPLIYPCSSREFKRAF 413
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.326 0.138 0.415
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,461,030
Number of Sequences: 37866
Number of extensions: 618928
Number of successful extensions: 3490
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 227
Number of HSP's successfully gapped in prelim test: 424
Number of HSP's that attempted gapping in prelim test: 2450
Number of HSP's gapped (non-prelim): 1013
length of query: 472
length of database: 18,247,518
effective HSP length: 106
effective length of query: 366
effective length of database: 14,233,722
effective search space: 5209542252
effective search space used: 5209542252
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.