Guide to the Human Genome
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Search of human proteins with 23397666

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|23397666 transcriptional co-repressor Sin3A [Homo sapiens]
         (1273 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|23397666 transcriptional co-repressor Sin3A [Homo sapiens]        2569   0.0  
gi|223941785 transcriptional co-repressor Sin3A [Homo sapiens]       2569   0.0  
gi|223941782 transcriptional co-repressor Sin3A [Homo sapiens]       2569   0.0  
gi|52138513 SIN3 homolog B, transcription regulator [Homo sapiens]   1148   0.0  
gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]       59   4e-08
gi|150378543 MYST histone acetyltransferase (monocytic leukemia)...    58   5e-08
gi|150378463 MYST histone acetyltransferase (monocytic leukemia)...    58   5e-08
gi|150378493 MYST histone acetyltransferase (monocytic leukemia)...    58   5e-08
gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]       57   1e-07
gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]          57   1e-07
gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]          57   1e-07
gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]          57   1e-07
gi|27262647 ataxin 2 related protein isoform A [Homo sapiens]          57   1e-07
gi|27262651 ataxin 2 related protein isoform D [Homo sapiens]          57   1e-07
gi|153792074 proline rich 12 [Homo sapiens]                            55   6e-07
gi|47132519 Ras association and pleckstrin homology domains 1 is...    53   2e-06
gi|19718731 bromodomain-containing protein 4 isoform long [Homo ...    52   3e-06
gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    51   6e-06
gi|38788260 bromodomain PHD finger transcription factor isoform ...    51   8e-06
gi|4826998 splicing factor proline/glutamine rich (polypyrimidin...    50   1e-05
gi|18959210 WIRE protein [Homo sapiens]                                50   1e-05
gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3 [...    50   2e-05
gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1 [...    50   2e-05
gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo sap...    50   2e-05
gi|126090663 zinc finger homeodomain 4 [Homo sapiens]                  49   3e-05
gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo sapi...    49   4e-05
gi|4557317 annexin A11 [Homo sapiens]                                  49   4e-05
gi|22165433 annexin A11 [Homo sapiens]                                 49   4e-05
gi|22165431 annexin A11 [Homo sapiens]                                 49   4e-05
gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo sapi...    48   5e-05

>gi|23397666 transcriptional co-repressor Sin3A [Homo sapiens]
          Length = 1273

 Score = 2569 bits (6659), Expect = 0.0
 Identities = 1273/1273 (100%), Positives = 1273/1273 (100%)

Query: 1    MKRRLDDQESPVYAAQQRRIPGSTEAFPHQHRVLAPAPPVYEAVSETMQSATGIQYSVTP 60
            MKRRLDDQESPVYAAQQRRIPGSTEAFPHQHRVLAPAPPVYEAVSETMQSATGIQYSVTP
Sbjct: 1    MKRRLDDQESPVYAAQQRRIPGSTEAFPHQHRVLAPAPPVYEAVSETMQSATGIQYSVTP 60

Query: 61   SYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQR 120
            SYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQR
Sbjct: 61   SYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQR 120

Query: 121  LKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIM 180
            LKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIM
Sbjct: 121  LKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIM 180

Query: 181  GFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQ 240
            GFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQ
Sbjct: 181  GFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQ 240

Query: 241  PAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQ 300
            PAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQ
Sbjct: 241  PAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQ 300

Query: 301  PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYA 360
            PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYA
Sbjct: 301  PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYA 360

Query: 361  QVARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRP 420
            QVARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRP
Sbjct: 361  QVARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRP 420

Query: 421  SQNGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAY 480
            SQNGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAY
Sbjct: 421  SQNGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAY 480

Query: 481  ENFLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLETYPKERATE 540
            ENFLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLETYPKERATE
Sbjct: 481  ENFLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLETYPKERATE 540

Query: 541  GIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWSEDSTFVSS 600
            GIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWSEDSTFVSS
Sbjct: 541  GIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWSEDSTFVSS 600

Query: 601  KKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGT 660
            KKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGT
Sbjct: 601  KKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGT 660

Query: 661  SEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQ 720
            SEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQ
Sbjct: 661  SEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQ 720

Query: 721  NEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLA 780
            NEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLA
Sbjct: 721  NEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLA 780

Query: 781  YEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEEEEE 840
            YEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEEEEE
Sbjct: 781  YEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEEEEE 840

Query: 841  EMDVDEATGAVKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQ 900
            EMDVDEATGAVKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQ
Sbjct: 841  EMDVDEATGAVKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQ 900

Query: 901  ILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYP 960
            ILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYP
Sbjct: 901  ILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYP 960

Query: 961  AFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQV 1020
            AFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQV
Sbjct: 961  AFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQV 1020

Query: 1021 TDLYLAENNNGATGGQLNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIE 1080
            TDLYLAENNNGATGGQLNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIE
Sbjct: 1021 TDLYLAENNNGATGGQLNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIE 1080

Query: 1081 LLDTEEENSDDPVEAERWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGR 1140
            LLDTEEENSDDPVEAERWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGR
Sbjct: 1081 LLDTEEENSDDPVEAERWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGR 1140

Query: 1141 EQQEKEGKEGNSKKTMENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHE 1200
            EQQEKEGKEGNSKKTMENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHE
Sbjct: 1141 EQQEKEGKEGNSKKTMENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHE 1200

Query: 1201 RVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSIN 1260
            RVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSIN
Sbjct: 1201 RVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSIN 1260

Query: 1261 KYRVKYGTVFKAP 1273
            KYRVKYGTVFKAP
Sbjct: 1261 KYRVKYGTVFKAP 1273


>gi|223941785 transcriptional co-repressor Sin3A [Homo sapiens]
          Length = 1273

 Score = 2569 bits (6659), Expect = 0.0
 Identities = 1273/1273 (100%), Positives = 1273/1273 (100%)

Query: 1    MKRRLDDQESPVYAAQQRRIPGSTEAFPHQHRVLAPAPPVYEAVSETMQSATGIQYSVTP 60
            MKRRLDDQESPVYAAQQRRIPGSTEAFPHQHRVLAPAPPVYEAVSETMQSATGIQYSVTP
Sbjct: 1    MKRRLDDQESPVYAAQQRRIPGSTEAFPHQHRVLAPAPPVYEAVSETMQSATGIQYSVTP 60

Query: 61   SYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQR 120
            SYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQR
Sbjct: 61   SYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQR 120

Query: 121  LKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIM 180
            LKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIM
Sbjct: 121  LKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIM 180

Query: 181  GFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQ 240
            GFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQ
Sbjct: 181  GFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQ 240

Query: 241  PAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQ 300
            PAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQ
Sbjct: 241  PAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQ 300

Query: 301  PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYA 360
            PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYA
Sbjct: 301  PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYA 360

Query: 361  QVARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRP 420
            QVARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRP
Sbjct: 361  QVARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRP 420

Query: 421  SQNGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAY 480
            SQNGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAY
Sbjct: 421  SQNGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAY 480

Query: 481  ENFLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLETYPKERATE 540
            ENFLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLETYPKERATE
Sbjct: 481  ENFLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLETYPKERATE 540

Query: 541  GIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWSEDSTFVSS 600
            GIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWSEDSTFVSS
Sbjct: 541  GIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWSEDSTFVSS 600

Query: 601  KKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGT 660
            KKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGT
Sbjct: 601  KKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGT 660

Query: 661  SEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQ 720
            SEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQ
Sbjct: 661  SEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQ 720

Query: 721  NEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLA 780
            NEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLA
Sbjct: 721  NEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLA 780

Query: 781  YEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEEEEE 840
            YEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEEEEE
Sbjct: 781  YEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEEEEE 840

Query: 841  EMDVDEATGAVKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQ 900
            EMDVDEATGAVKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQ
Sbjct: 841  EMDVDEATGAVKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQ 900

Query: 901  ILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYP 960
            ILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYP
Sbjct: 901  ILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYP 960

Query: 961  AFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQV 1020
            AFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQV
Sbjct: 961  AFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQV 1020

Query: 1021 TDLYLAENNNGATGGQLNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIE 1080
            TDLYLAENNNGATGGQLNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIE
Sbjct: 1021 TDLYLAENNNGATGGQLNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIE 1080

Query: 1081 LLDTEEENSDDPVEAERWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGR 1140
            LLDTEEENSDDPVEAERWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGR
Sbjct: 1081 LLDTEEENSDDPVEAERWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGR 1140

Query: 1141 EQQEKEGKEGNSKKTMENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHE 1200
            EQQEKEGKEGNSKKTMENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHE
Sbjct: 1141 EQQEKEGKEGNSKKTMENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHE 1200

Query: 1201 RVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSIN 1260
            RVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSIN
Sbjct: 1201 RVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSIN 1260

Query: 1261 KYRVKYGTVFKAP 1273
            KYRVKYGTVFKAP
Sbjct: 1261 KYRVKYGTVFKAP 1273


>gi|223941782 transcriptional co-repressor Sin3A [Homo sapiens]
          Length = 1273

 Score = 2569 bits (6659), Expect = 0.0
 Identities = 1273/1273 (100%), Positives = 1273/1273 (100%)

Query: 1    MKRRLDDQESPVYAAQQRRIPGSTEAFPHQHRVLAPAPPVYEAVSETMQSATGIQYSVTP 60
            MKRRLDDQESPVYAAQQRRIPGSTEAFPHQHRVLAPAPPVYEAVSETMQSATGIQYSVTP
Sbjct: 1    MKRRLDDQESPVYAAQQRRIPGSTEAFPHQHRVLAPAPPVYEAVSETMQSATGIQYSVTP 60

Query: 61   SYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQR 120
            SYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQR
Sbjct: 61   SYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQR 120

Query: 121  LKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIM 180
            LKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIM
Sbjct: 121  LKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIM 180

Query: 181  GFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQ 240
            GFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQ
Sbjct: 181  GFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQ 240

Query: 241  PAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQ 300
            PAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQ
Sbjct: 241  PAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQ 300

Query: 301  PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYA 360
            PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYA
Sbjct: 301  PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYA 360

Query: 361  QVARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRP 420
            QVARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRP
Sbjct: 361  QVARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRP 420

Query: 421  SQNGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAY 480
            SQNGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAY
Sbjct: 421  SQNGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAY 480

Query: 481  ENFLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLETYPKERATE 540
            ENFLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLETYPKERATE
Sbjct: 481  ENFLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLETYPKERATE 540

Query: 541  GIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWSEDSTFVSS 600
            GIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWSEDSTFVSS
Sbjct: 541  GIAMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKEVLNDTWVSFPSWSEDSTFVSS 600

Query: 601  KKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGT 660
            KKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGT
Sbjct: 601  KKTQYEEHIYRCEDERFELDVVLETNLATIRVLEAIQKKLSRLSAEEQAKFRLDNTLGGT 660

Query: 661  SEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQ 720
            SEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQ
Sbjct: 661  SEVIHRKALQRIYADKAADIIDGLRKNPSIAVPIVLKRLKMKEEEWREAQRGFNKVWREQ 720

Query: 721  NEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLA 780
            NEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLA
Sbjct: 721  NEKYYLKSLDHQGINFKQNDTKVLRSKSLLNEIESIYDERQEQATEENAGVPVGPHLSLA 780

Query: 781  YEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEEEEE 840
            YEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEEEEE
Sbjct: 781  YEDKQILEDAAALIIHHVKRQTGIQKEDKYKIKQIMHHFIPDLLFAQRGDLSDVEEEEEE 840

Query: 841  EMDVDEATGAVKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQ 900
            EMDVDEATGAVKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQ
Sbjct: 841  EMDVDEATGAVKKHNGVGGSPPKSKLLFSNTAAQKLRGMDEVYNLFYVNNNWYIFMRLHQ 900

Query: 901  ILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYP 960
            ILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYP
Sbjct: 901  ILCLRLLRICSQAERQIEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYP 960

Query: 961  AFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQV 1020
            AFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQV
Sbjct: 961  AFLDMVRSLLDGNIDSSQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQV 1020

Query: 1021 TDLYLAENNNGATGGQLNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIE 1080
            TDLYLAENNNGATGGQLNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIE
Sbjct: 1021 TDLYLAENNNGATGGQLNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIE 1080

Query: 1081 LLDTEEENSDDPVEAERWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGR 1140
            LLDTEEENSDDPVEAERWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGR
Sbjct: 1081 LLDTEEENSDDPVEAERWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGR 1140

Query: 1141 EQQEKEGKEGNSKKTMENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHE 1200
            EQQEKEGKEGNSKKTMENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHE
Sbjct: 1141 EQQEKEGKEGNSKKTMENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHE 1200

Query: 1201 RVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSIN 1260
            RVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSIN
Sbjct: 1201 RVSKRLHQRFQAWVDKWTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSIN 1260

Query: 1261 KYRVKYGTVFKAP 1273
            KYRVKYGTVFKAP
Sbjct: 1261 KYRVKYGTVFKAP 1273


>gi|52138513 SIN3 homolog B, transcription regulator [Homo sapiens]
          Length = 1162

 Score = 1148 bits (2969), Expect = 0.0
 Identities = 611/1190 (51%), Positives = 789/1190 (66%), Gaps = 121/1190 (10%)

Query: 123  VEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGF 182
            VEDAL+YLDQVK++FGS P  YN FL+IMKEFKSQSIDTPGVI RVSQLF  HPDLI+GF
Sbjct: 41   VEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSIDTPGVIRRVSQLFHEHPDLIVGF 100

Query: 183  NTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPA 242
            N FLP GY+I++  N  +N+ +P                      SQ ++ +    A+  
Sbjct: 101  NAFLPLGYRIDIPKNGKLNIQSP--------------------LTSQENSHNHGDGAEDF 140

Query: 243  PQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQPV 302
             Q  P K  KP           Q P                               +  V
Sbjct: 141  KQQVPYKEDKP-----------QVP-----------------------------LESDSV 160

Query: 303  EFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQV 362
            EFN+AI+YVNKIK RF   P+IY++FLEILHTYQKEQ N +   G     ++E+EV+ +V
Sbjct: 161  EFNNAISYVNKIKTRFLDHPEIYRSFLEILHTYQKEQLNTR---GRPFRGMSEEEVFTEV 217

Query: 363  ARLFKNQEDLLSEFGQFLPDANSSVLLSKTTAEKVDSVRNDHGGTVKKPQLNNKPQRPSQ 422
            A LF+ QEDLLSEFGQFLP+A  S+       E     +N+H    K P+ + K  RPS 
Sbjct: 218  ANLFRGQEDLLSEFGQFLPEAKRSLFTGNGPCEMHSVQKNEHD---KTPEHSRKRSRPSL 274

Query: 423  NGCQIRRHPTGTTPPVKKKPKLLNLKDSSMADASKHGGGTESLFFDKVRKALRSAEAYEN 482
                        + P KKK KL   KD S+A   K+G   E  FFDKVR+ L+S E YEN
Sbjct: 275  L--------RPVSAPAKKKMKLRGTKDLSIAAVGKYGTLQEFSFFDKVRRVLKSQEVYEN 326

Query: 483  FLRCLVIFNQEVISRAELVQLVSPFLGKFPELFNWFKNFLGYKESVHLETYPKERATEGI 542
            FLRC+ +FNQE++S +EL+QLVSPFLGKFPELF  FK+FLG KE +       +R+ +GI
Sbjct: 327  FLRCIALFNQELVSGSELLQLVSPFLGKFPELFAQFKSFLGVKE-LSFAPPMSDRSGDGI 385

Query: 543  AMEIDYASCKRLGSSYRALPKSYQQPKCTGRTPLCKE----------------------- 579
            + EIDYASCKR+GSSYRALPK+YQQPKC+GRT +CKE                       
Sbjct: 386  SREIDYASCKRIGSSYRALPKTYQQPKCSGRTAICKELDHWTLLQGSWTDDYCMSKFKNT 445

Query: 580  ---------VLNDTWVSFPSWSEDSTFVSSKKTQYEEHIYRCEDERFELDVVLETNLATI 630
                     VLNDTWVSFPSWSEDSTFVSSKKT YEE ++RCEDERFELDVVLETNLATI
Sbjct: 446  CWIPGYSAGVLNDTWVSFPSWSEDSTFVSSKKTPYEEQLHRCEDERFELDVVLETNLATI 505

Query: 631  RVLEAIQKKLSRLSAEEQAKFRLDNTLGGTSEVIHRKALQRIYADKAADIIDGLRKNPSI 690
            RVLE++QKKLSR++ E+Q KFRLD++LGGTSEVI R+A+ RIY DKA +II+ L+KNP  
Sbjct: 506  RVLESVQKKLSRMAPEDQEKFRLDDSLGGTSEVIQRRAIYRIYGDKAPEIIESLKKNPVT 565

Query: 691  AVPIVLKRLKMKEEEWREAQRGFNKVWREQNEKYYLKSLDHQGINFKQNDTKVLRSKSLL 750
            AVP+VLKRLK KEEEWREAQ+GFNK+WREQ EK YLKSLDHQ +NFKQNDTK LRSKSLL
Sbjct: 566  AVPVVLKRLKAKEEEWREAQQGFNKIWREQYEKAYLKSLDHQAVNFKQNDTKALRSKSLL 625

Query: 751  NEIESIYDERQEQATEENAGVPVGPHLSLAYEDKQILEDAAALIIHHVKRQTGIQKEDKY 810
            NEIES+YDE QEQ +E  +     PHL   YED+QILEDAAALI ++VKRQ  IQKED+ 
Sbjct: 626  NEIESVYDEHQEQHSEGRSAPSSEPHLIFVYEDRQILEDAAALISYYVKRQPAIQKEDQG 685

Query: 811  KIKQIMHHFIPDLLFAQRGDLSDVEEEEEEEMD-----VDEATGAVKKHNGVGGSPPKSK 865
             I Q++H F+P L F+Q+ DL   EE  +E+ D       + +   K   G   SPP+ K
Sbjct: 686  TIHQLLHQFVPSLFFSQQLDLGASEESADEDRDSPQGQTTDPSERKKPAPGPHSSPPEEK 745

Query: 866  LLFSNTAAQKL---------RGMDEVYNLFYVNNNWYIFMRLHQILCLRLLRICSQAERQ 916
              F +  A +          + +D+VY+LF+ NNNWY F+RLHQ LC RLL+I  QA++Q
Sbjct: 746  GAFGDAPATEQPPLPPPAPHKPLDDVYSLFFANNNWYFFLRLHQTLCSRLLKIYRQAQKQ 805

Query: 917  IEEENREREWEREVLGIKRDKSDSPAIQLRLKEPMDVDVEDYYPAFLDMVRSLLDGNIDS 976
            + E   E+E E+ +   +R+K   PA++LRLK+P +V++E+YYPAFLDMVRSLL+G+ID 
Sbjct: 806  LLEYRTEKEREKLLCEGRREKGSDPAMELRLKQPSEVELEEYYPAFLDMVRSLLEGSIDP 865

Query: 977  SQYEDSLREMFTIHAYIAFTMDKLIQSIVRQLQHIVSDEICVQVTDLYLAENNNGATGGQ 1036
            +QYED+LREMFTIHAY+ FTMDKL+Q+I RQL H+VSD++C++V +LYL E   GA GG 
Sbjct: 866  TQYEDTLREMFTIHAYVGFTMDKLVQNIARQLHHLVSDDVCLKVVELYLNEKKRGAAGGN 925

Query: 1037 LNTQNSRSLLESTYQRKAEQLMSDENCFKLMFIQSQGQVQLTIELLDTEEENSDDPVEAE 1096
            L+++  R+  E++YQ KAE+ M+DENCFK+MF+Q +GQV +TIELLDTEE  ++DPVE +
Sbjct: 926  LSSRCVRAARETSYQWKAERCMADENCFKVMFLQRKGQVIMTIELLDTEEAQTEDPVEVQ 985

Query: 1097 RWSDYVERYMNSDTTSPELREHLAQKPVFLPRNLRRIRKCQRGREQQEKEGKEGNSKKTM 1156
              + YVE+Y+ ++  S    E    KPVFL RNL++ R+  +  + +   G+  +S K +
Sbjct: 986  HLARYVEQYVGTEGASSSPTEGFLLKPVFLQRNLKKFRRRWQSEQARALRGEARSSWKRL 1045

Query: 1157 ENVDSLDKLECRFKLNSYKMVYVIKSEDYMYRRTALLRAHQSHERVSKRLHQRFQAWVDK 1216
              V+S   ++CRFKL+++KMV+++ SEDYMYRR  L RA Q    V  R HQ F+ W  +
Sbjct: 1046 VGVESACDVDCRFKLSTHKMVFIVNSEDYMYRRGTLCRAKQVQPLVLLRHHQHFEEWHSR 1105

Query: 1217 WTKEHVPREMAAETSKWLMGEGLEGLVPCTTTCDTETLHFVSINKYRVKY 1266
            W +++V  E A+    WLMGE  E +VPC T C+T  +H + + +YRV+Y
Sbjct: 1106 WLEDNVTVEAASLVQDWLMGEEDEDMVPCKTLCETVHVHGLPVTRYRVQY 1155



 Score = 58.9 bits (141), Expect = 3e-08
 Identities = 40/172 (23%), Positives = 75/172 (43%), Gaps = 25/172 (14%)

Query: 78  IAAVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQF 137
           + +  +SH+H    +    QV      P  P+       +   ++  +A+SY++++K +F
Sbjct: 124 LTSQENSHNHGDGAEDFKQQVPYKEDKPQVPL-------ESDSVEFNNAISYVNKIKTRF 176

Query: 138 GSQPQVYNDFLDIMKEFKSQSIDTPG----------VISRVSQLFKGHPDLIMGFNTFLP 187
              P++Y  FL+I+  ++ + ++T G          V + V+ LF+G  DL+  F  FLP
Sbjct: 177 LDHPEIYRSFLEILHTYQKEQLNTRGRPFRGMSEEEVFTEVANLFRGQEDLLSEFGQFLP 236

Query: 188 PGYKIEVQTNDMVNVTTPGQVHQIP--THGIQPQPQPPPQHPSQPSAQSAPA 237
              +       +     P ++H +    H   P+       PS     SAPA
Sbjct: 237 EAKR------SLFTGNGPCEMHSVQKNEHDKTPEHSRKRSRPSLLRPVSAPA 282



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 32/127 (25%), Positives = 53/127 (41%), Gaps = 20/127 (15%)

Query: 301 PVEFNHAINYVNKIKNRFQGQPDIYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYA 360
           PV    A+ Y++++K RF   P  Y  FLEI+  ++ +  +        TP      V  
Sbjct: 38  PVHVEDALTYLDQVKIRFGSDPATYNGFLEIMKEFKSQSID--------TPG-----VIR 84

Query: 361 QVARLFKNQEDLLSEFGQFLP-------DANSSVLLSKTTAEKVDSVRNDHGGTVKKPQL 413
           +V++LF    DL+  F  FLP         N  + +      + +S  +  G    K Q+
Sbjct: 85  RVSQLFHEHPDLIVGFNAFLPLGYRIDIPKNGKLNIQSPLTSQENSHNHGDGAEDFKQQV 144

Query: 414 NNKPQRP 420
             K  +P
Sbjct: 145 PYKEDKP 151


>gi|51477700 mediator complex subunit 15 isoform a [Homo sapiens]
          Length = 788

 Score = 58.5 bits (140), Expect = 4e-08
 Identities = 67/261 (25%), Positives = 101/261 (38%), Gaps = 31/261 (11%)

Query: 46  ETMQSATGIQYSVTPSYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHGGQVVQSHAHP 105
           +  Q A   Q  +         P  S +    +  +H + HH    QP    V Q+    
Sbjct: 258 QQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQ 317

Query: 106 APPVA---PVQGQQQF---QRLKVEDALSYL--DQVKLQFGSQPQVYNDFLDIMKEFKSQ 157
            PP +   P+  Q Q    Q L  +  L ++    V  Q   QPQV      +     +Q
Sbjct: 318 LPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQVQQQQTAVQTAQAAQ 377

Query: 158 SIDTPGVISRVSQLFKGHPDLIMGF----------NTFLPPGYKIEVQTND----MVNVT 203
            +  PGV      L +G   +   F          ++ +P G +   Q +     M++  
Sbjct: 378 MV-APGVQMITEALAQGGMHIRARFPPTTAVSAIPSSSIPLGRQPMAQVSQSSLPMLSSP 436

Query: 204 TPGQVHQIPTHGIQPQPQPPPQHPSQPSAQ------SAPAPAQPAPQPPPAKVSKPSQLQ 257
           +PGQ  Q P   + P PQP PQ P QPS+Q      S PAP+  +  P P+     S + 
Sbjct: 437 SPGQQVQTP-QSMPPPPQPSPQ-PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVT 494

Query: 258 AHTPASQQTPPLPPYASPRSP 278
           A TP +   P   P  +P +P
Sbjct: 495 ARTPQNFSVPSPGPLNTPVNP 515



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 8/72 (11%)

Query: 217 QPQPQPPPQHPSQPSAQSAPAPAQPA---PQPPPAKVSKPSQLQAHTPASQQTPPLPPYA 273
           Q Q Q   Q   Q + Q+ P   QP    PQPPP++       Q H     Q PP     
Sbjct: 249 QQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPP----- 303

Query: 274 SPRSPPVQPHTP 285
            P+ PPV  + P
Sbjct: 304 QPQQPPVAQNQP 315



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 32/114 (28%), Positives = 41/114 (35%), Gaps = 25/114 (21%)

Query: 207 QVHQIPTHGIQPQP---QPPPQHPSQPSAQSAPAPAQPAP-----QPPPAKVSKPSQLQA 258
           Q  Q     +Q QP   QPP Q P  P +Q+ P   Q        QPPP    +P Q   
Sbjct: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPP----QPQQ--- 307

Query: 259 HTPASQQTPPLPPYASPRSPPVQP---------HTPVTISLGTAPSLQNNQPVE 303
             P +Q  P   P  S   P V           +T   +    AP +    PV+
Sbjct: 308 -PPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQ 360


>gi|150378543 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 78/335 (23%), Positives = 114/335 (34%), Gaps = 55/335 (16%)

Query: 6    DDQESPVYAAQQRRIPGSTEAFPHQHRVLAPAPPVYEAVSETMQSATGIQYSVTPSYQVS 65
            DD E   +  ++       E  PH    L     V     E      G       +    
Sbjct: 1394 DDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAAC 1453

Query: 66   AMPQS--SGSHGPAIAAV---HSSHHHP--TAVQPHGGQVVQSHAHPAPP--------VA 110
               QS       P ++ V   H+S H+   ++VQ H  Q V+S + P  P        ++
Sbjct: 1454 QTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQIS 1513

Query: 111  PVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLD--------------------- 149
            P QG      ++  +    +D   +   SQ  V + F D                     
Sbjct: 1514 PEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTM 1573

Query: 150  ---IMKEFKSQSIDTPGVISRVSQLFKGHPDLI-----MGFNTFLPPGYKIEVQTNDMVN 201
               I     SQS  + G +S  S L +    +      MG +  +     ++   N  + 
Sbjct: 1574 GGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIK 1633

Query: 202  VTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTP 261
                  V + P++  Q  P PPPQ P  P     P   QPAPQPPP +     Q Q   P
Sbjct: 1634 SPQSCVVERPPSNQQQQPPPPPPQQPQPP-----PPQPQPAPQPPPPQQQPQQQPQ---P 1685

Query: 262  ASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSL 296
              QQ PP PP   P+  P      +  S   AP +
Sbjct: 1686 QPQQPPPPPP---PQQQPPLSQCSMNNSFTPAPMI 1717


>gi|150378463 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 78/335 (23%), Positives = 114/335 (34%), Gaps = 55/335 (16%)

Query: 6    DDQESPVYAAQQRRIPGSTEAFPHQHRVLAPAPPVYEAVSETMQSATGIQYSVTPSYQVS 65
            DD E   +  ++       E  PH    L     V     E      G       +    
Sbjct: 1394 DDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAAC 1453

Query: 66   AMPQS--SGSHGPAIAAV---HSSHHHP--TAVQPHGGQVVQSHAHPAPP--------VA 110
               QS       P ++ V   H+S H+   ++VQ H  Q V+S + P  P        ++
Sbjct: 1454 QTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQIS 1513

Query: 111  PVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLD--------------------- 149
            P QG      ++  +    +D   +   SQ  V + F D                     
Sbjct: 1514 PEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTM 1573

Query: 150  ---IMKEFKSQSIDTPGVISRVSQLFKGHPDLI-----MGFNTFLPPGYKIEVQTNDMVN 201
               I     SQS  + G +S  S L +    +      MG +  +     ++   N  + 
Sbjct: 1574 GGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIK 1633

Query: 202  VTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTP 261
                  V + P++  Q  P PPPQ P  P     P   QPAPQPPP +     Q Q   P
Sbjct: 1634 SPQSCVVERPPSNQQQQPPPPPPQQPQPP-----PPQPQPAPQPPPPQQQPQQQPQ---P 1685

Query: 262  ASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSL 296
              QQ PP PP   P+  P      +  S   AP +
Sbjct: 1686 QPQQPPPPPP---PQQQPPLSQCSMNNSFTPAPMI 1717


>gi|150378493 MYST histone acetyltransferase (monocytic leukemia) 3
            [Homo sapiens]
          Length = 2004

 Score = 58.2 bits (139), Expect = 5e-08
 Identities = 78/335 (23%), Positives = 114/335 (34%), Gaps = 55/335 (16%)

Query: 6    DDQESPVYAAQQRRIPGSTEAFPHQHRVLAPAPPVYEAVSETMQSATGIQYSVTPSYQVS 65
            DD E   +  ++       E  PH    L     V     E      G       +    
Sbjct: 1394 DDHEEDSHTKEELIELKEEEEIPHSELDLETVQAVQSLTQEESSEHEGAYQDCEETLAAC 1453

Query: 66   AMPQS--SGSHGPAIAAV---HSSHHHP--TAVQPHGGQVVQSHAHPAPP--------VA 110
               QS       P ++ V   H+S H+   ++VQ H  Q V+S + P  P        ++
Sbjct: 1454 QTLQSYTQADEDPQMSMVEDCHASEHNSPISSVQSHPSQSVRSVSSPNVPALESGYTQIS 1513

Query: 111  PVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLD--------------------- 149
            P QG      ++  +    +D   +   SQ  V + F D                     
Sbjct: 1514 PEQGSLSAPSMQNMETSPMMDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTM 1573

Query: 150  ---IMKEFKSQSIDTPGVISRVSQLFKGHPDLI-----MGFNTFLPPGYKIEVQTNDMVN 201
               I     SQS  + G +S  S L +    +      MG +  +     ++   N  + 
Sbjct: 1574 GGSICGNSSSQSSCSYGGLSSSSSLTQSSCVVTQQMASMGSSCSMMQQSSVQPAANCSIK 1633

Query: 202  VTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTP 261
                  V + P++  Q  P PPPQ P  P     P   QPAPQPPP +     Q Q   P
Sbjct: 1634 SPQSCVVERPPSNQQQQPPPPPPQQPQPP-----PPQPQPAPQPPPPQQQPQQQPQ---P 1685

Query: 262  ASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSL 296
              QQ PP PP   P+  P      +  S   AP +
Sbjct: 1686 QPQQPPPPPP---PQQQPPLSQCSMNNSFTPAPMI 1717


>gi|21312134 mediator complex subunit 15 isoform b [Homo sapiens]
          Length = 748

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 62/247 (25%), Positives = 94/247 (38%), Gaps = 43/247 (17%)

Query: 46  ETMQSATGIQYSVTPSYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHGGQVVQSHAHP 105
           +  Q A   Q  +         P  S +    +  +H + HH    QP    V Q+    
Sbjct: 258 QQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQPSQ 317

Query: 106 APPVA---PVQGQQQF---QRLKVEDALSYL--DQVKLQFGSQPQVYNDFLDIMKEFKSQ 157
            PP +   P+  Q Q    Q L  +  L ++    V  Q   QPQV             Q
Sbjct: 318 LPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPVQPQV-------------Q 364

Query: 158 SIDTPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQ 217
              T    ++ +Q+              + PG ++   +  M++  +PGQ  Q P   + 
Sbjct: 365 QQQTAVQTAQAAQM--------------VAPGVQVSQSSLPMLSSPSPGQQVQTP-QSMP 409

Query: 218 PQPQPPPQHPSQPSAQ------SAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPP 271
           P PQP PQ P QPS+Q      S PAP+  +  P P+     S + A TP +   P   P
Sbjct: 410 PPPQPSPQ-PGQPSSQPNSNVSSGPAPSPSSFLPSPSPQPSQSPVTARTPQNFSVPSPGP 468

Query: 272 YASPRSP 278
             +P +P
Sbjct: 469 LNTPVNP 475



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 35/109 (32%), Positives = 41/109 (37%), Gaps = 33/109 (30%)

Query: 207 QVHQIPTHGIQPQP---QPPPQHPSQPSAQSAPAPAQ-----------PAPQPPPAKVSK 252
           Q  Q     +Q QP   QPP Q P  P +Q+ P   Q           P PQ PP   ++
Sbjct: 255 QQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPPQPQQPPVAQNQ 314

Query: 253 PSQLQAHTPASQQTPPL---------------PPYASPRSPPVQPHTPV 286
           PSQL    P   QT PL               PP    R+P V    PV
Sbjct: 315 PSQL----PPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAPMVVQQPPV 359



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 24/72 (33%), Positives = 30/72 (41%), Gaps = 8/72 (11%)

Query: 217 QPQPQPPPQHPSQPSAQSAPAPAQPA---PQPPPAKVSKPSQLQAHTPASQQTPPLPPYA 273
           Q Q Q   Q   Q + Q+ P   QP    PQPPP++       Q H     Q PP     
Sbjct: 249 QQQQQQQQQQQQQQALQAQPPIQQPPMQQPQPPPSQALPQQLQQMHHTQHHQPPP----- 303

Query: 274 SPRSPPVQPHTP 285
            P+ PPV  + P
Sbjct: 304 QPQQPPVAQNQP 315



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 35/130 (26%), Positives = 41/130 (31%), Gaps = 35/130 (26%)

Query: 207 QVHQIPTHGIQPQPQPPPQHPSQPS--------------AQSAPA--------------- 237
           Q+H    H   PQPQ PP   +QPS              AQ+ P                
Sbjct: 292 QMHHTQHHQPPPQPQQPPVAQNQPSQLPPQSQTQPLVSQAQALPGQMLYTQPPLKFVRAP 351

Query: 238 ------PAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLG 291
                 P QP  Q     V      Q   P  Q +    P  S  SP  Q  TP ++   
Sbjct: 352 MVVQQPPVQPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQVQTPQSMPPP 411

Query: 292 TAPSLQNNQP 301
             PS Q  QP
Sbjct: 412 PQPSPQPGQP 421



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 34/97 (35%), Positives = 41/97 (42%), Gaps = 11/97 (11%)

Query: 202 VTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAP--APAQPAPQPPPAKVSKPSQ-LQA 258
           V  P  V Q P      QPQ   Q  +  +AQ+A   AP     Q     +S PS   Q 
Sbjct: 348 VRAPMVVQQPPV-----QPQVQQQQTAVQTAQAAQMVAPGVQVSQSSLPMLSSPSPGQQV 402

Query: 259 HTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPS 295
            TP S   PP P    P  P  QP++   +S G APS
Sbjct: 403 QTPQSMPPPPQPS-PQPGQPSSQPNS--NVSSGPAPS 436


>gi|27262645 ataxin 2 related protein isoform B [Homo sapiens]
          Length = 1062

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 67/250 (26%), Positives = 92/250 (36%), Gaps = 32/250 (12%)

Query: 39  PVYEAVSETMQSATGIQYSVTPSYQVS-AMPQSSGSHGPAIAAV---HSSHHHPTAVQPH 94
           P Y +    +     +Q      Y VS ++P   G +  A  ++    S  H P +  P 
Sbjct: 708 PQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP- 766

Query: 95  GGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEF 154
              ++Q+ A   PP+                  SY+     QF  QP +    +  M  +
Sbjct: 767 ---MMQAAAAAGPPLVAATPYS-----------SYIPYNPQQFPGQPAM----MQPMAHY 808

Query: 155 KSQSIDTPGVISRVSQLFKG-HPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQV---HQ 210
            SQ +  P + S    L  G HP  I+  +T   P Y    Q        T  Q    H 
Sbjct: 809 PSQPVFAPMLQSNPRMLTSGSHPQAIVSSST---PQYPSAEQPTPQALYATVHQSYPHHA 865

Query: 211 IPTHGIQPQPQPPPQHPSQPSAQSAPAPAQ-PAPQPPPAKVSKPSQLQAHTPASQQTPP- 268
              H  QPQP   P      S  +AP+P Q  A Q P     +P Q   H  A   TPP 
Sbjct: 866 TQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPS 925

Query: 269 LPPYASPRSP 278
           LPP  S +SP
Sbjct: 926 LPPGPSAQSP 935



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 64/280 (22%), Positives = 86/280 (30%), Gaps = 60/280 (21%)

Query: 20   IPGSTEAFPHQHRVLAPAP---------PVYEAVSETMQSAT---GIQYSVTPSYQVSAM 67
            IP + + FP Q  ++ P           P+ ++    + S +    I  S TP Y  +  
Sbjct: 788  IPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQ 847

Query: 68   PQSSGSHGPAIAAVHSSH-HHPTAVQPHGGQVVQSHAH-PAPPVAPVQGQQQFQRLKVED 125
            P     +    A VH S+ HH T          Q HAH P P   P   Q Q Q      
Sbjct: 848  PTPQALY----ATVHQSYPHHAT----------QLHAHQPQPATTPTGSQPQSQHAAPSP 893

Query: 126  ALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTF 185
                  Q       QPQ                            L+  HP  + G    
Sbjct: 894  VQHQAGQAPHLGSGQPQ--------------------------QNLY--HPGALTGTPPS 925

Query: 186  LPPGYKIEVQTNDMVNVTTPGQVH--QIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAP 243
            LPPG   +   +          +H  Q+P HG          H  Q    +AP P   AP
Sbjct: 926  LPPGPSAQSPQSSFPQPAAVYAIHHQQLP-HGFTNMAHVTQAHV-QTGITAAPPPHPGAP 983

Query: 244  QPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPH 283
             PP   +  P Q     P         P  S  +P   P+
Sbjct: 984  HPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPY 1023



 Score = 38.5 bits (88), Expect = 0.041
 Identities = 68/283 (24%), Positives = 106/283 (37%), Gaps = 32/283 (11%)

Query: 36  PAPPVYEAVSETMQSATGIQYSVTPSYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHG 95
           P PP+  AV  T  ++  +  SV+     S  P S     P I+   +     +  +P  
Sbjct: 463 PEPPIGSAVP-TSSASIPVTSSVSDPGVGSISPAS-----PKISLAPTDVKELSTKEPGR 516

Query: 96  GQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFK 155
               Q  A  A  V  +Q +Q+  R ++E+   +  Q KLQ  S P+             
Sbjct: 517 TLEPQELARIAGKVPGLQNEQK--RFQLEELRKFGAQFKLQPSSSPE------------- 561

Query: 156 SQSIDT--PGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPT 213
             S+D   P ++       KG    + G  T  P G  +  +T  + +      +   P+
Sbjct: 562 -NSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPL--APS 615

Query: 214 HGIQPQPQPPPQHPSQP-SAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPY 272
            G +   QPPP  PSQ  S        +   + P A+  K S L  +      T PL   
Sbjct: 616 GGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSV 675

Query: 273 ASPRSPPVQPHTPVTISLGTAPSLQNNQPVEFN-HAINYVNKI 314
               S P  P  P T S  + P L   Q   ++   I+Y+ +I
Sbjct: 676 NKSTSTPTSP-GPRTHSTPSIPVLTAGQSGLYSPQYISYIPQI 717



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 32/94 (34%), Positives = 39/94 (41%), Gaps = 15/94 (15%)

Query: 213 THGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKP-----SQLQAHTPASQQTP 267
           T G  PQ       P  PSA+      QP PQ   A V +      +QL AH P    TP
Sbjct: 826 TSGSHPQAIVSSSTPQYPSAE------QPTPQALYATVHQSYPHHATQLHAHQPQPATTP 879

Query: 268 PLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQP 301
                + P+S    P +PV    G AP L + QP
Sbjct: 880 T---GSQPQSQHAAP-SPVQHQAGQAPHLGSGQP 909



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 6/66 (9%)

Query: 216 IQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPP-YAS 274
           ++PQP   P  P QP     P   Q   + PP   S P+       A+   PP PP  AS
Sbjct: 2   LKPQPLQQPSQPQQP-----PPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAAS 56

Query: 275 PRSPPV 280
           P   PV
Sbjct: 57  PCLGPV 62



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 30/119 (25%), Positives = 43/119 (36%), Gaps = 5/119 (4%)

Query: 192 IEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVS 251
           I V T     + +P  +  IP   + P  Q P  +P  P + S P   Q           
Sbjct: 695 IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYP-YPVSNSVPG--QQGKYRGAKGSL 751

Query: 252 KPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQPVEFNHAINY 310
            P +   H PAS   PP+   A+   PP+   TP +  +   P     QP       +Y
Sbjct: 752 PPQRSDQHQPAS--APPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHY 808


>gi|27262653 ataxin 2 related protein isoform E [Homo sapiens]
          Length = 1044

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 67/250 (26%), Positives = 92/250 (36%), Gaps = 32/250 (12%)

Query: 39  PVYEAVSETMQSATGIQYSVTPSYQVS-AMPQSSGSHGPAIAAV---HSSHHHPTAVQPH 94
           P Y +    +     +Q      Y VS ++P   G +  A  ++    S  H P +  P 
Sbjct: 708 PQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP- 766

Query: 95  GGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEF 154
              ++Q+ A   PP+                  SY+     QF  QP +    +  M  +
Sbjct: 767 ---MMQAAAAAGPPLVAATPYS-----------SYIPYNPQQFPGQPAM----MQPMAHY 808

Query: 155 KSQSIDTPGVISRVSQLFKG-HPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQV---HQ 210
            SQ +  P + S    L  G HP  I+  +T   P Y    Q        T  Q    H 
Sbjct: 809 PSQPVFAPMLQSNPRMLTSGSHPQAIVSSST---PQYPSAEQPTPQALYATVHQSYPHHA 865

Query: 211 IPTHGIQPQPQPPPQHPSQPSAQSAPAPAQ-PAPQPPPAKVSKPSQLQAHTPASQQTPP- 268
              H  QPQP   P      S  +AP+P Q  A Q P     +P Q   H  A   TPP 
Sbjct: 866 TQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPS 925

Query: 269 LPPYASPRSP 278
           LPP  S +SP
Sbjct: 926 LPPGPSAQSP 935



 Score = 43.9 bits (102), Expect = 0.001
 Identities = 70/298 (23%), Positives = 94/298 (31%), Gaps = 71/298 (23%)

Query: 20   IPGSTEAFPHQHRVLAPAP---------PVYEAVSETMQSAT---GIQYSVTPSYQVSAM 67
            IP + + FP Q  ++ P           P+ ++    + S +    I  S TP Y  +  
Sbjct: 788  IPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQ 847

Query: 68   PQSSGSHGPAIAAVHSSH-HHPTAVQPHGGQVVQSHAH-PAPPVAPVQGQQQFQRLKVED 125
            P     +    A VH S+ HH T          Q HAH P P   P   Q Q Q      
Sbjct: 848  PTPQALY----ATVHQSYPHHAT----------QLHAHQPQPATTPTGSQPQSQHAAPSP 893

Query: 126  ALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTF 185
                  Q       QPQ                            L+  HP  + G    
Sbjct: 894  VQHQAGQAPHLGSGQPQ--------------------------QNLY--HPGALTGTPPS 925

Query: 186  LPPGYKIEVQTNDMVNVTTPGQVH--QIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAP 243
            LPPG   +   +          +H  Q+P HG          H  Q    +AP P   AP
Sbjct: 926  LPPGPSAQSPQSSFPQPAAVYAIHHQQLP-HGFTNMAHVTQAHV-QTGITAAPPPHPGAP 983

Query: 244  QPPPAKVSKPSQL----------QAHTPASQQTPPLP-PYASPRSPPVQPHTPVTISL 290
             PP   +  P Q           Q+  PA   + P P PY      P+ P   + I L
Sbjct: 984  HPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPYIGHPQAPLPPPGELKIVL 1041



 Score = 38.5 bits (88), Expect = 0.041
 Identities = 68/283 (24%), Positives = 106/283 (37%), Gaps = 32/283 (11%)

Query: 36  PAPPVYEAVSETMQSATGIQYSVTPSYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHG 95
           P PP+  AV  T  ++  +  SV+     S  P S     P I+   +     +  +P  
Sbjct: 463 PEPPIGSAVP-TSSASIPVTSSVSDPGVGSISPAS-----PKISLAPTDVKELSTKEPGR 516

Query: 96  GQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFK 155
               Q  A  A  V  +Q +Q+  R ++E+   +  Q KLQ  S P+             
Sbjct: 517 TLEPQELARIAGKVPGLQNEQK--RFQLEELRKFGAQFKLQPSSSPE------------- 561

Query: 156 SQSIDT--PGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPT 213
             S+D   P ++       KG    + G  T  P G  +  +T  + +      +   P+
Sbjct: 562 -NSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPL--APS 615

Query: 214 HGIQPQPQPPPQHPSQP-SAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPY 272
            G +   QPPP  PSQ  S        +   + P A+  K S L  +      T PL   
Sbjct: 616 GGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSV 675

Query: 273 ASPRSPPVQPHTPVTISLGTAPSLQNNQPVEFN-HAINYVNKI 314
               S P  P  P T S  + P L   Q   ++   I+Y+ +I
Sbjct: 676 NKSTSTPTSP-GPRTHSTPSIPVLTAGQSGLYSPQYISYIPQI 717



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 32/94 (34%), Positives = 39/94 (41%), Gaps = 15/94 (15%)

Query: 213 THGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKP-----SQLQAHTPASQQTP 267
           T G  PQ       P  PSA+      QP PQ   A V +      +QL AH P    TP
Sbjct: 826 TSGSHPQAIVSSSTPQYPSAE------QPTPQALYATVHQSYPHHATQLHAHQPQPATTP 879

Query: 268 PLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQP 301
                + P+S    P +PV    G AP L + QP
Sbjct: 880 T---GSQPQSQHAAP-SPVQHQAGQAPHLGSGQP 909



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 6/66 (9%)

Query: 216 IQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPP-YAS 274
           ++PQP   P  P QP     P   Q   + PP   S P+       A+   PP PP  AS
Sbjct: 2   LKPQPLQQPSQPQQP-----PPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAAS 56

Query: 275 PRSPPV 280
           P   PV
Sbjct: 57  PCLGPV 62



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 30/119 (25%), Positives = 43/119 (36%), Gaps = 5/119 (4%)

Query: 192 IEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVS 251
           I V T     + +P  +  IP   + P  Q P  +P  P + S P   Q           
Sbjct: 695 IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYP-YPVSNSVPG--QQGKYRGAKGSL 751

Query: 252 KPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQPVEFNHAINY 310
            P +   H PAS   PP+   A+   PP+   TP +  +   P     QP       +Y
Sbjct: 752 PPQRSDQHQPAS--APPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHY 808


>gi|27262649 ataxin 2 related protein isoform C [Homo sapiens]
          Length = 1097

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 67/250 (26%), Positives = 92/250 (36%), Gaps = 32/250 (12%)

Query: 39  PVYEAVSETMQSATGIQYSVTPSYQVS-AMPQSSGSHGPAIAAV---HSSHHHPTAVQPH 94
           P Y +    +     +Q      Y VS ++P   G +  A  ++    S  H P +  P 
Sbjct: 708 PQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP- 766

Query: 95  GGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEF 154
              ++Q+ A   PP+                  SY+     QF  QP +    +  M  +
Sbjct: 767 ---MMQAAAAAGPPLVAATPYS-----------SYIPYNPQQFPGQPAM----MQPMAHY 808

Query: 155 KSQSIDTPGVISRVSQLFKG-HPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQV---HQ 210
            SQ +  P + S    L  G HP  I+  +T   P Y    Q        T  Q    H 
Sbjct: 809 PSQPVFAPMLQSNPRMLTSGSHPQAIVSSST---PQYPSAEQPTPQALYATVHQSYPHHA 865

Query: 211 IPTHGIQPQPQPPPQHPSQPSAQSAPAPAQ-PAPQPPPAKVSKPSQLQAHTPASQQTPP- 268
              H  QPQP   P      S  +AP+P Q  A Q P     +P Q   H  A   TPP 
Sbjct: 866 TQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPS 925

Query: 269 LPPYASPRSP 278
           LPP  S +SP
Sbjct: 926 LPPGPSAQSP 935



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 64/280 (22%), Positives = 86/280 (30%), Gaps = 60/280 (21%)

Query: 20   IPGSTEAFPHQHRVLAPAP---------PVYEAVSETMQSAT---GIQYSVTPSYQVSAM 67
            IP + + FP Q  ++ P           P+ ++    + S +    I  S TP Y  +  
Sbjct: 788  IPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQ 847

Query: 68   PQSSGSHGPAIAAVHSSH-HHPTAVQPHGGQVVQSHAH-PAPPVAPVQGQQQFQRLKVED 125
            P     +    A VH S+ HH T          Q HAH P P   P   Q Q Q      
Sbjct: 848  PTPQALY----ATVHQSYPHHAT----------QLHAHQPQPATTPTGSQPQSQHAAPSP 893

Query: 126  ALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTF 185
                  Q       QPQ                            L+  HP  + G    
Sbjct: 894  VQHQAGQAPHLGSGQPQ--------------------------QNLY--HPGALTGTPPS 925

Query: 186  LPPGYKIEVQTNDMVNVTTPGQVH--QIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAP 243
            LPPG   +   +          +H  Q+P HG          H  Q    +AP P   AP
Sbjct: 926  LPPGPSAQSPQSSFPQPAAVYAIHHQQLP-HGFTNMAHVTQAHV-QTGITAAPPPHPGAP 983

Query: 244  QPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPH 283
             PP   +  P Q     P         P  S  +P   P+
Sbjct: 984  HPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPY 1023



 Score = 38.5 bits (88), Expect = 0.041
 Identities = 68/283 (24%), Positives = 106/283 (37%), Gaps = 32/283 (11%)

Query: 36  PAPPVYEAVSETMQSATGIQYSVTPSYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHG 95
           P PP+  AV  T  ++  +  SV+     S  P S     P I+   +     +  +P  
Sbjct: 463 PEPPIGSAVP-TSSASIPVTSSVSDPGVGSISPAS-----PKISLAPTDVKELSTKEPGR 516

Query: 96  GQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFK 155
               Q  A  A  V  +Q +Q+  R ++E+   +  Q KLQ  S P+             
Sbjct: 517 TLEPQELARIAGKVPGLQNEQK--RFQLEELRKFGAQFKLQPSSSPE------------- 561

Query: 156 SQSIDT--PGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPT 213
             S+D   P ++       KG    + G  T  P G  +  +T  + +      +   P+
Sbjct: 562 -NSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPL--APS 615

Query: 214 HGIQPQPQPPPQHPSQP-SAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPY 272
            G +   QPPP  PSQ  S        +   + P A+  K S L  +      T PL   
Sbjct: 616 GGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSV 675

Query: 273 ASPRSPPVQPHTPVTISLGTAPSLQNNQPVEFN-HAINYVNKI 314
               S P  P  P T S  + P L   Q   ++   I+Y+ +I
Sbjct: 676 NKSTSTPTSP-GPRTHSTPSIPVLTAGQSGLYSPQYISYIPQI 717



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 32/94 (34%), Positives = 39/94 (41%), Gaps = 15/94 (15%)

Query: 213 THGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKP-----SQLQAHTPASQQTP 267
           T G  PQ       P  PSA+      QP PQ   A V +      +QL AH P    TP
Sbjct: 826 TSGSHPQAIVSSSTPQYPSAE------QPTPQALYATVHQSYPHHATQLHAHQPQPATTP 879

Query: 268 PLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQP 301
                + P+S    P +PV    G AP L + QP
Sbjct: 880 T---GSQPQSQHAAP-SPVQHQAGQAPHLGSGQP 909



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 6/66 (9%)

Query: 216 IQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPP-YAS 274
           ++PQP   P  P QP     P   Q   + PP   S P+       A+   PP PP  AS
Sbjct: 2   LKPQPLQQPSQPQQP-----PPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAAS 56

Query: 275 PRSPPV 280
           P   PV
Sbjct: 57  PCLGPV 62



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 30/119 (25%), Positives = 43/119 (36%), Gaps = 5/119 (4%)

Query: 192 IEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVS 251
           I V T     + +P  +  IP   + P  Q P  +P  P + S P   Q           
Sbjct: 695 IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYP-YPVSNSVPG--QQGKYRGAKGSL 751

Query: 252 KPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQPVEFNHAINY 310
            P +   H PAS   PP+   A+   PP+   TP +  +   P     QP       +Y
Sbjct: 752 PPQRSDQHQPAS--APPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHY 808


>gi|27262647 ataxin 2 related protein isoform A [Homo sapiens]
          Length = 1075

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 67/250 (26%), Positives = 92/250 (36%), Gaps = 32/250 (12%)

Query: 39  PVYEAVSETMQSATGIQYSVTPSYQVS-AMPQSSGSHGPAIAAV---HSSHHHPTAVQPH 94
           P Y +    +     +Q      Y VS ++P   G +  A  ++    S  H P +  P 
Sbjct: 708 PQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP- 766

Query: 95  GGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEF 154
              ++Q+ A   PP+                  SY+     QF  QP +    +  M  +
Sbjct: 767 ---MMQAAAAAGPPLVAATPYS-----------SYIPYNPQQFPGQPAM----MQPMAHY 808

Query: 155 KSQSIDTPGVISRVSQLFKG-HPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQV---HQ 210
            SQ +  P + S    L  G HP  I+  +T   P Y    Q        T  Q    H 
Sbjct: 809 PSQPVFAPMLQSNPRMLTSGSHPQAIVSSST---PQYPSAEQPTPQALYATVHQSYPHHA 865

Query: 211 IPTHGIQPQPQPPPQHPSQPSAQSAPAPAQ-PAPQPPPAKVSKPSQLQAHTPASQQTPP- 268
              H  QPQP   P      S  +AP+P Q  A Q P     +P Q   H  A   TPP 
Sbjct: 866 TQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPS 925

Query: 269 LPPYASPRSP 278
           LPP  S +SP
Sbjct: 926 LPPGPSAQSP 935



 Score = 42.4 bits (98), Expect = 0.003
 Identities = 64/280 (22%), Positives = 86/280 (30%), Gaps = 60/280 (21%)

Query: 20   IPGSTEAFPHQHRVLAPAP---------PVYEAVSETMQSAT---GIQYSVTPSYQVSAM 67
            IP + + FP Q  ++ P           P+ ++    + S +    I  S TP Y  +  
Sbjct: 788  IPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQ 847

Query: 68   PQSSGSHGPAIAAVHSSH-HHPTAVQPHGGQVVQSHAH-PAPPVAPVQGQQQFQRLKVED 125
            P     +    A VH S+ HH T          Q HAH P P   P   Q Q Q      
Sbjct: 848  PTPQALY----ATVHQSYPHHAT----------QLHAHQPQPATTPTGSQPQSQHAAPSP 893

Query: 126  ALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTF 185
                  Q       QPQ                            L+  HP  + G    
Sbjct: 894  VQHQAGQAPHLGSGQPQ--------------------------QNLY--HPGALTGTPPS 925

Query: 186  LPPGYKIEVQTNDMVNVTTPGQVH--QIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAP 243
            LPPG   +   +          +H  Q+P HG          H  Q    +AP P   AP
Sbjct: 926  LPPGPSAQSPQSSFPQPAAVYAIHHQQLP-HGFTNMAHVTQAHV-QTGITAAPPPHPGAP 983

Query: 244  QPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPH 283
             PP   +  P Q     P         P  S  +P   P+
Sbjct: 984  HPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTPSPYPY 1023



 Score = 38.5 bits (88), Expect = 0.041
 Identities = 68/283 (24%), Positives = 106/283 (37%), Gaps = 32/283 (11%)

Query: 36  PAPPVYEAVSETMQSATGIQYSVTPSYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHG 95
           P PP+  AV  T  ++  +  SV+     S  P S     P I+   +     +  +P  
Sbjct: 463 PEPPIGSAVP-TSSASIPVTSSVSDPGVGSISPAS-----PKISLAPTDVKELSTKEPGR 516

Query: 96  GQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFK 155
               Q  A  A  V  +Q +Q+  R ++E+   +  Q KLQ  S P+             
Sbjct: 517 TLEPQELARIAGKVPGLQNEQK--RFQLEELRKFGAQFKLQPSSSPE------------- 561

Query: 156 SQSIDT--PGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPT 213
             S+D   P ++       KG    + G  T  P G  +  +T  + +      +   P+
Sbjct: 562 -NSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPL--APS 615

Query: 214 HGIQPQPQPPPQHPSQP-SAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPY 272
            G +   QPPP  PSQ  S        +   + P A+  K S L  +      T PL   
Sbjct: 616 GGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSV 675

Query: 273 ASPRSPPVQPHTPVTISLGTAPSLQNNQPVEFN-HAINYVNKI 314
               S P  P  P T S  + P L   Q   ++   I+Y+ +I
Sbjct: 676 NKSTSTPTSP-GPRTHSTPSIPVLTAGQSGLYSPQYISYIPQI 717



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 32/94 (34%), Positives = 39/94 (41%), Gaps = 15/94 (15%)

Query: 213 THGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKP-----SQLQAHTPASQQTP 267
           T G  PQ       P  PSA+      QP PQ   A V +      +QL AH P    TP
Sbjct: 826 TSGSHPQAIVSSSTPQYPSAE------QPTPQALYATVHQSYPHHATQLHAHQPQPATTP 879

Query: 268 PLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQP 301
                + P+S    P +PV    G AP L + QP
Sbjct: 880 T---GSQPQSQHAAP-SPVQHQAGQAPHLGSGQP 909



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 6/66 (9%)

Query: 216 IQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPP-YAS 274
           ++PQP   P  P QP     P   Q   + PP   S P+       A+   PP PP  AS
Sbjct: 2   LKPQPLQQPSQPQQP-----PPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAAS 56

Query: 275 PRSPPV 280
           P   PV
Sbjct: 57  PCLGPV 62



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 30/119 (25%), Positives = 43/119 (36%), Gaps = 5/119 (4%)

Query: 192 IEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVS 251
           I V T     + +P  +  IP   + P  Q P  +P  P + S P   Q           
Sbjct: 695 IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYP-YPVSNSVPG--QQGKYRGAKGSL 751

Query: 252 KPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQPVEFNHAINY 310
            P +   H PAS   PP+   A+   PP+   TP +  +   P     QP       +Y
Sbjct: 752 PPQRSDQHQPAS--APPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHY 808


>gi|27262651 ataxin 2 related protein isoform D [Homo sapiens]
          Length = 1044

 Score = 56.6 bits (135), Expect = 1e-07
 Identities = 67/250 (26%), Positives = 92/250 (36%), Gaps = 32/250 (12%)

Query: 39  PVYEAVSETMQSATGIQYSVTPSYQVS-AMPQSSGSHGPAIAAV---HSSHHHPTAVQPH 94
           P Y +    +     +Q      Y VS ++P   G +  A  ++    S  H P +  P 
Sbjct: 708 PQYISYIPQIHMGPAVQAPQMYPYPVSNSVPGQQGKYRGAKGSLPPQRSDQHQPASAPP- 766

Query: 95  GGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEF 154
              ++Q+ A   PP+                  SY+     QF  QP +    +  M  +
Sbjct: 767 ---MMQAAAAAGPPLVAATPYS-----------SYIPYNPQQFPGQPAM----MQPMAHY 808

Query: 155 KSQSIDTPGVISRVSQLFKG-HPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQV---HQ 210
            SQ +  P + S    L  G HP  I+  +T   P Y    Q        T  Q    H 
Sbjct: 809 PSQPVFAPMLQSNPRMLTSGSHPQAIVSSST---PQYPSAEQPTPQALYATVHQSYPHHA 865

Query: 211 IPTHGIQPQPQPPPQHPSQPSAQSAPAPAQ-PAPQPPPAKVSKPSQLQAHTPASQQTPP- 268
              H  QPQP   P      S  +AP+P Q  A Q P     +P Q   H  A   TPP 
Sbjct: 866 TQLHAHQPQPATTPTGSQPQSQHAAPSPVQHQAGQAPHLGSGQPQQNLYHPGALTGTPPS 925

Query: 269 LPPYASPRSP 278
           LPP  S +SP
Sbjct: 926 LPPGPSAQSP 935



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 69/290 (23%), Positives = 91/290 (31%), Gaps = 71/290 (24%)

Query: 20   IPGSTEAFPHQHRVLAPAP---------PVYEAVSETMQSAT---GIQYSVTPSYQVSAM 67
            IP + + FP Q  ++ P           P+ ++    + S +    I  S TP Y  +  
Sbjct: 788  IPYNPQQFPGQPAMMQPMAHYPSQPVFAPMLQSNPRMLTSGSHPQAIVSSSTPQYPSAEQ 847

Query: 68   PQSSGSHGPAIAAVHSSH-HHPTAVQPHGGQVVQSHAH-PAPPVAPVQGQQQFQRLKVED 125
            P     +    A VH S+ HH T          Q HAH P P   P   Q Q Q      
Sbjct: 848  PTPQALY----ATVHQSYPHHAT----------QLHAHQPQPATTPTGSQPQSQHAAPSP 893

Query: 126  ALSYLDQVKLQFGSQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTF 185
                  Q       QPQ                            L+  HP  + G    
Sbjct: 894  VQHQAGQAPHLGSGQPQ--------------------------QNLY--HPGALTGTPPS 925

Query: 186  LPPGYKIEVQTNDMVNVTTPGQVH--QIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAP 243
            LPPG   +   +          +H  Q+P HG          H  Q    +AP P   AP
Sbjct: 926  LPPGPSAQSPQSSFPQPAAVYAIHHQQLP-HGFTNMAHVTQAHV-QTGITAAPPPHPGAP 983

Query: 244  QPPPAKVSKPSQL----------QAHTPASQQTPPLPPYASPRSPPVQPH 283
             PP   +  P Q           Q+  PA   + P  PY     P VQ H
Sbjct: 984  HPPQVMLLHPPQSHGGPPQGAVPQSGVPALSASTP-SPYPYIGHPQVQSH 1032



 Score = 38.5 bits (88), Expect = 0.041
 Identities = 68/283 (24%), Positives = 106/283 (37%), Gaps = 32/283 (11%)

Query: 36  PAPPVYEAVSETMQSATGIQYSVTPSYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQPHG 95
           P PP+  AV  T  ++  +  SV+     S  P S     P I+   +     +  +P  
Sbjct: 463 PEPPIGSAVP-TSSASIPVTSSVSDPGVGSISPAS-----PKISLAPTDVKELSTKEPGR 516

Query: 96  GQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKEFK 155
               Q  A  A  V  +Q +Q+  R ++E+   +  Q KLQ  S P+             
Sbjct: 517 TLEPQELARIAGKVPGLQNEQK--RFQLEELRKFGAQFKLQPSSSPE------------- 561

Query: 156 SQSIDT--PGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPT 213
             S+D   P ++       KG    + G  T  P G  +  +T  + +      +   P+
Sbjct: 562 -NSLDPFPPRILKEEP---KGKEKEVDGLLTSEPMGSPVSSKTESVSDKEDKPPL--APS 615

Query: 214 HGIQPQPQPPPQHPSQP-SAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPY 272
            G +   QPPP  PSQ  S        +   + P A+  K S L  +      T PL   
Sbjct: 616 GGTEGPEQPPPPCPSQTGSPPVGLIKGEDKDEGPVAEQVKKSTLNPNAKEFNPTKPLLSV 675

Query: 273 ASPRSPPVQPHTPVTISLGTAPSLQNNQPVEFN-HAINYVNKI 314
               S P  P  P T S  + P L   Q   ++   I+Y+ +I
Sbjct: 676 NKSTSTPTSP-GPRTHSTPSIPVLTAGQSGLYSPQYISYIPQI 717



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 32/94 (34%), Positives = 39/94 (41%), Gaps = 15/94 (15%)

Query: 213 THGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKP-----SQLQAHTPASQQTP 267
           T G  PQ       P  PSA+      QP PQ   A V +      +QL AH P    TP
Sbjct: 826 TSGSHPQAIVSSSTPQYPSAE------QPTPQALYATVHQSYPHHATQLHAHQPQPATTP 879

Query: 268 PLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQP 301
                + P+S    P +PV    G AP L + QP
Sbjct: 880 T---GSQPQSQHAAP-SPVQHQAGQAPHLGSGQP 909



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 23/66 (34%), Positives = 28/66 (42%), Gaps = 6/66 (9%)

Query: 216 IQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPP-YAS 274
           ++PQP   P  P QP     P   Q   + PP   S P+       A+   PP PP  AS
Sbjct: 2   LKPQPLQQPSQPQQP-----PPTQQAVARRPPGGTSPPNGGLPGPLATSAAPPGPPAAAS 56

Query: 275 PRSPPV 280
           P   PV
Sbjct: 57  PCLGPV 62



 Score = 32.7 bits (73), Expect = 2.3
 Identities = 30/119 (25%), Positives = 43/119 (36%), Gaps = 5/119 (4%)

Query: 192 IEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVS 251
           I V T     + +P  +  IP   + P  Q P  +P  P + S P   Q           
Sbjct: 695 IPVLTAGQSGLYSPQYISYIPQIHMGPAVQAPQMYP-YPVSNSVPG--QQGKYRGAKGSL 751

Query: 252 KPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQPVEFNHAINY 310
            P +   H PAS   PP+   A+   PP+   TP +  +   P     QP       +Y
Sbjct: 752 PPQRSDQHQPAS--APPMMQAAAAAGPPLVAATPYSSYIPYNPQQFPGQPAMMQPMAHY 808


>gi|153792074 proline rich 12 [Homo sapiens]
          Length = 2036

 Score = 54.7 bits (130), Expect = 6e-07
 Identities = 33/80 (41%), Positives = 35/80 (43%), Gaps = 10/80 (12%)

Query: 217  QPQPQPPPQHPSQPSAQSAPAPAQPA-PQPPPAKVSKPSQLQAHTPASQQTPPLPPYASP 275
            +P P PPP    QP     P P QPA P PPP        L A TP+S   PPLPP   P
Sbjct: 1456 KPPPTPPPAPTPQPQPPPPPPPPQPALPSPPP--------LVAPTPSSPPPPPLPPPPPP 1507

Query: 276  RSP-PVQPHTPVTISLGTAP 294
              P P  P  P    L   P
Sbjct: 1508 AMPSPPPPPPPAAAPLAAPP 1527



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 28/75 (37%), Positives = 35/75 (46%), Gaps = 7/75 (9%)

Query: 212  PTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPP 271
            PT   QP P PPP  P+ PS     AP   +P PPP     P  + +        PP PP
Sbjct: 1465 PTPQPQPPPPPPPPQPALPSPPPLVAPTPSSPPPPPLPPPPPPAMPS------PPPPPPP 1518

Query: 272  YASP-RSPPVQPHTP 285
             A+P  +PP +P  P
Sbjct: 1519 AAAPLAAPPEEPAAP 1533



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 30/88 (34%), Positives = 32/88 (36%), Gaps = 18/88 (20%)

Query: 220  PQPPPQHPSQPSAQSAPAPA------QPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYA 273
            P PPP  P  PSA S   P       +P P PPPA   +P           Q PP PP  
Sbjct: 1431 PGPPPL-PGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQP-----------QPPPPPPPP 1478

Query: 274  SPRSPPVQPHTPVTISLGTAPSLQNNQP 301
             P  P   P    T S    P L    P
Sbjct: 1479 QPALPSPPPLVAPTPSSPPPPPLPPPPP 1506



 Score = 37.4 bits (85), Expect = 0.092
 Identities = 28/76 (36%), Positives = 35/76 (46%), Gaps = 20/76 (26%)

Query: 218 PQPQPPPQH-PSQ-----PSAQSAPAPAQPAPQ----------PPPAKVSKPSQ----LQ 257
           P P PPP+H P+Q      S+ +A A  Q +PQ          PPP + + P Q      
Sbjct: 232 PDPPPPPRHLPTQFNLLASSSAAAAAAEQSSPQLYNFSGAAPGPPPPERALPRQDTVIKH 291

Query: 258 AHTPASQQTPPLPPYA 273
              PAS Q PP PP A
Sbjct: 292 YQRPASAQPPPPPPPA 307



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 32/105 (30%), Positives = 43/105 (40%), Gaps = 12/105 (11%)

Query: 187 PPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQ------HPSQPSAQSAPAPAQ 240
           P G  +E    D+  V  P     +P+  +   P P P       H  +P+ +   AP Q
Sbjct: 778 PHGLLLEAGGPDLPLVLPPPPPQLLPSV-LSHAPSPSPSASKVGVHLLEPATRDG-AP-Q 834

Query: 241 PAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTP 285
           P P PPP     P QL+AH  +    P  P   SPR  P +   P
Sbjct: 835 PPPPPPPPPPPMPLQLEAHLRSHGLEPAAP---SPRLRPEESLDP 876



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 26/80 (32%), Positives = 33/80 (41%), Gaps = 3/80 (3%)

Query: 220  PQPPPQHPSQPSAQS-APAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPP--LPPYASPR 276
            P   P+  S P     APA A P P P P   S  S      P  ++ PP   PP  +P+
Sbjct: 1409 PLAGPKDTSTPDGPPLAPAAAVPGPPPLPGLPSANSNGTPEPPLLEEKPPPTPPPAPTPQ 1468

Query: 277  SPPVQPHTPVTISLGTAPSL 296
              P  P  P   +L + P L
Sbjct: 1469 PQPPPPPPPPQPALPSPPPL 1488



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 16/44 (36%), Positives = 19/44 (43%)

Query: 218  PQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTP 261
            P P PPP  P+ PS    P PA      PP + + PS      P
Sbjct: 1498 PPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELP 1541



 Score = 33.9 bits (76), Expect = 1.0
 Identities = 25/87 (28%), Positives = 31/87 (35%), Gaps = 11/87 (12%)

Query: 212  PTHGIQPQPQPP---PQHPSQPSAQSAPAPAQPA--------PQPPPAKVSKPSQLQAHT 260
            P  G  P P PP   P  P  P   S   P  P         P+ P    ++P  L    
Sbjct: 974  PKAGAGPPPGPPAYDPYGPYCPGRASGAGPETPGLGLDPNKPPELPSTVNAEPLGLIQSG 1033

Query: 261  PASQQTPPLPPYASPRSPPVQPHTPVT 287
            P     PP PP   P +P  +P   +T
Sbjct: 1034 PHQAAPPPPPPPPPPPAPASEPKGGLT 1060



 Score = 33.1 bits (74), Expect = 1.7
 Identities = 15/45 (33%), Positives = 20/45 (44%)

Query: 212  PTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQL 256
            P     P P PPP   + P A     PA P+P+ P    ++P  L
Sbjct: 1504 PPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPLHL 1548



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 26/87 (29%), Positives = 29/87 (33%), Gaps = 23/87 (26%)

Query: 219 QPQPPPQHPSQPSAQSAP--------APAQPAPQPPPAKVSKPSQLQ------------- 257
           Q  PPP  P+  S Q  P         P  P   PPP     PS L              
Sbjct: 761 QKSPPPPPPTAQSTQPTPHGLLLEAGGPDLPLVLPPPPPQLLPSVLSHAPSPSPSASKVG 820

Query: 258 AHT--PASQQTPPLPPYASPRSPPVQP 282
            H   PA++   P PP   P  PP  P
Sbjct: 821 VHLLEPATRDGAPQPPPPPPPPPPPMP 847



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 17/50 (34%), Positives = 20/50 (40%)

Query: 220  PQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPL 269
            P PP   P  P+  S P P  PA  P  A   +P+      P    T PL
Sbjct: 1497 PPPPLPPPPPPAMPSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRPL 1546



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 16/38 (42%), Positives = 18/38 (47%), Gaps = 4/38 (10%)

Query: 215 GIQPQPQPP----PQHPSQPSAQSAPAPAQPAPQPPPA 248
           G  P P PP    P+  +       PA AQP P PPPA
Sbjct: 270 GAAPGPPPPERALPRQDTVIKHYQRPASAQPPPPPPPA 307



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 16/52 (30%), Positives = 21/52 (40%), Gaps = 2/52 (3%)

Query: 220  PQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPP 271
            P PPP  P  P A   P+P  P P       + P +  A +P   + P   P
Sbjct: 1496 PPPPPLPPPPPPAM--PSPPPPPPPAAAPLAAPPEEPAAPSPEDPELPDTRP 1545



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 22/85 (25%), Positives = 31/85 (36%), Gaps = 5/85 (5%)

Query: 194  VQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKP 253
            V   D V V      H+ P   +  +     ++P      SAP P  PAP P P    K 
Sbjct: 1653 VNKKDYVRVCARKPWHRPP---VPVRRSGQAKNPVSAGGSSAPPPKAPAPPPKPETPEKT 1709

Query: 254  SQLQAHTPASQQTPPLPPYASPRSP 278
            +  +      +   P PP  +P  P
Sbjct: 1710 TSEKPPEQTPETAMPEPP--APEKP 1732


>gi|47132519 Ras association and pleckstrin homology domains 1
           isoform 1 [Homo sapiens]
          Length = 1250

 Score = 53.1 bits (126), Expect = 2e-06
 Identities = 37/91 (40%), Positives = 46/91 (50%), Gaps = 11/91 (12%)

Query: 211 IPTHGIQPQPQPPPQHPSQPS--AQSAPAPAQPA-PQ----PPPAKVSKPSQLQAHTPAS 263
           +P +G+ P P PPP  P+  S  AQ  PAP  P+ PQ    PPP K+    Q+Q  T  +
Sbjct: 703 VPPNGVVPPPPPPPPPPTPGSAMAQLKPAPCAPSLPQFSAPPPPLKI---HQVQHITQVA 759

Query: 264 QQTPPLPPYASPRSPPVQPHTP-VTISLGTA 293
             TPP PP      PP  P  P VTI   T+
Sbjct: 760 PPTPPPPPPIPAPLPPQAPPKPLVTIPAPTS 790



 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 41/130 (31%), Positives = 54/130 (41%), Gaps = 14/130 (10%)

Query: 205 PGQVHQIP--THGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPA 262
           P ++HQ+   T    P P PPP  P+    Q+ P P    P P   K   P   QA  P 
Sbjct: 746 PLKIHQVQHITQVAPPTPPPPPPIPAPLPPQAPPKPLVTIPAPTSTKTVAPVVTQAAPPT 805

Query: 263 SQQTPPLPPY----ASPRS--PPVQPHTPVTISLGTAPSLQN----NQPVEFNHAINYVN 312
              TPP+PP     A P S  PP  P  PV +   T P  Q+      P   +   + V 
Sbjct: 806 --PTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVK 863

Query: 313 KIKNRFQGQP 322
           +I ++F   P
Sbjct: 864 QIASQFPPPP 873



 Score = 47.8 bits (112), Expect = 7e-05
 Identities = 28/68 (41%), Positives = 32/68 (47%), Gaps = 1/68 (1%)

Query: 216 IQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPA-SQQTPPLPPYAS 274
           I  Q  PPP  P+  S    P PA  APQ PPA  +KP    +  P  S   PP PP +S
Sbjct: 865 IASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPVPSPDFPPPPPESS 924

Query: 275 PRSPPVQP 282
              PP  P
Sbjct: 925 LVFPPPPP 932



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 26/84 (30%), Positives = 31/84 (36%), Gaps = 18/84 (21%)

Query: 216 IQPQPQ-PPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYAS 274
           + PQP+   P   SQPS    P P  P P PPP                   PP PP  S
Sbjct: 609 LSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPP-----------------PPPPPLPS 651

Query: 275 PRSPPVQPHTPVTISLGTAPSLQN 298
             +P      P+ +   T   LQN
Sbjct: 652 QSAPSAGSAAPMFVKYSTITRLQN 675



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 31/132 (23%), Positives = 48/132 (36%), Gaps = 6/132 (4%)

Query: 162 PGVISRVSQLFKGHPDL-IMGFNTFLPPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQP 220
           P V+ +++  F   P    M      P    +  Q+   V      Q   IP     P P
Sbjct: 859 PSVVKQIASQFPPPPTPPAMESQPLKPVPANVAPQSPPAVKAKPKWQPSSIPV----PSP 914

Query: 221 QPPPQHPSQPSAQSAPAPAQ-PAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPP 279
             PP  P        P P+  PAP PPP   + P+  ++ +P  + +    P      P 
Sbjct: 915 DFPPPPPESSLVFPPPPPSPVPAPPPPPPPTASPTPDKSGSPGKKTSKTSSPGGKKPPPT 974

Query: 280 VQPHTPVTISLG 291
            Q ++ +  S G
Sbjct: 975 PQRNSSIKSSSG 986



 Score = 37.7 bits (86), Expect = 0.071
 Identities = 31/94 (32%), Positives = 39/94 (41%), Gaps = 14/94 (14%)

Query: 202 VTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQ-----PPPAKVSKPSQL 256
           + TP    Q P+  + P P PPP  P  P     P P+Q AP      P   K S  ++L
Sbjct: 615 IVTPYTASQ-PSPPLPPPPPPPPPPPPPPPPPPPPLPSQSAPSAGSAAPMFVKYSTITRL 673

Query: 257 QAHTPASQQT-----PPLPPYASPRSPPVQPHTP 285
           Q    ASQ +     PP PP    +S   Q   P
Sbjct: 674 Q---NASQHSGALFKPPTPPVMQSQSVKPQILVP 704



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 26/84 (30%), Positives = 33/84 (39%), Gaps = 17/84 (20%)

Query: 212 PTHGIQPQPQPPPQHPSQPS--AQSAPAPAQPAP--------QPPPAKVSKPSQLQAHTP 261
           P+    P P PPP  P Q S  A+  P+P  P P        Q PP       +      
Sbjct: 826 PSPPTPPVPVPPPTLPKQQSFCAKPPPSPLSPVPSVVKQIASQFPPPPTPPAME------ 879

Query: 262 ASQQTPPLPPYASPRSPPVQPHTP 285
            SQ   P+P   +P+SPP     P
Sbjct: 880 -SQPLKPVPANVAPQSPPAVKAKP 902



 Score = 35.4 bits (80), Expect = 0.35
 Identities = 60/271 (22%), Positives = 91/271 (33%), Gaps = 49/271 (18%)

Query: 36  PAPPVYEAVSETMQSATG--IQYSVTPSYQVSAMPQSSGSHGPAIAAVHSSHHHPTAVQP 93
           P PP+    + +  SA    ++YS     Q ++    +    P    + S    P  + P
Sbjct: 645 PPPPLPSQSAPSAGSAAPMFVKYSTITRLQNASQHSGALFKPPTPPVMQSQSVKPQILVP 704

Query: 94  HGGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGSQPQVYNDFLDIMKE 153
             G VV     P PP  P     Q +      +L        QF + P      L I + 
Sbjct: 705 PNG-VVPPPPPPPPPPTPGSAMAQLKPAPCAPSLP-------QFSAPPPP----LKIHQ- 751

Query: 154 FKSQSIDTPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTNDMVNVTTPGQ---VHQ 210
                      +  ++Q+    P         LPP    +     +V +  P     V  
Sbjct: 752 -----------VQHITQVAPPTPPPPPPIPAPLPP----QAPPKPLVTIPAPTSTKTVAP 796

Query: 211 IPTHGIQPQPQPP----PQHPSQPSAQSAPAP-AQPAPQPPPAKVSKPSQLQAHTPASQQ 265
           + T    P P PP     + P+ P++   P+P   P P PPP  + K     A  P S  
Sbjct: 797 VVTQAAPPTPTPPVPPAKKQPAFPASYIPPSPPTPPVPVPPPT-LPKQQSFCAKPPPSPL 855

Query: 266 TP----------PLPPYASPRSPPVQPHTPV 286
           +P            PP  +P +   QP  PV
Sbjct: 856 SPVPSVVKQIASQFPPPPTPPAMESQPLKPV 886



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 22/95 (23%), Positives = 38/95 (40%), Gaps = 6/95 (6%)

Query: 232 AQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLG 291
           + + P  +   P  P  K+  P      +P     PP PP   P  PP  P  P      
Sbjct: 597 SMNRPYTSLVPPLSPQPKIVTPYTASQPSPPLPPPPPPPPPPPPPPPPPPPPLPSQ---- 652

Query: 292 TAPSLQNNQPVEFNHAINYVNKIKNRFQGQPDIYK 326
           +APS  +  P+   ++   + +++N  Q    ++K
Sbjct: 653 SAPSAGSAAPMFVKYST--ITRLQNASQHSGALFK 685



 Score = 31.2 bits (69), Expect = 6.6
 Identities = 24/87 (27%), Positives = 34/87 (39%), Gaps = 5/87 (5%)

Query: 219 QPQPPPQHPSQ---PSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASP 275
           +P  PP   SQ   P     P    P P PPP     P    A    +   P LP +++P
Sbjct: 685 KPPTPPVMQSQSVKPQILVPPNGVVPPPPPPP-PPPTPGSAMAQLKPAPCAPSLPQFSAP 743

Query: 276 RSPPVQPHTPVTISLGTAPSLQNNQPV 302
             PP++ H    I+    P+     P+
Sbjct: 744 -PPPLKIHQVQHITQVAPPTPPPPPPI 769



 Score = 30.8 bits (68), Expect = 8.6
 Identities = 29/112 (25%), Positives = 41/112 (36%), Gaps = 34/112 (30%)

Query: 223  PPQHPSQPSAQSAPAPAQPAPQPPPAK-----VSKPSQLQ-------------------- 257
            PP     PS ++ P PA P   P P K     V+ P  LQ                    
Sbjct: 1006 PPAESGSPSKETLPPPAAP---PKPGKLNLSGVNLPGVLQQGCVSAKAPVLSGRGKDSVV 1062

Query: 258  --AHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAP--SLQNNQPVEFN 305
                 P+    PP PP      PP++   P   S  T+P  ++ N QP +++
Sbjct: 1063 EFPSPPSDSDFPPPPPETELPLPPIE--IPAVFSGNTSPKVAVVNPQPQQWS 1112


>gi|19718731 bromodomain-containing protein 4 isoform long [Homo
            sapiens]
          Length = 1362

 Score = 52.4 bits (124), Expect = 3e-06
 Identities = 31/83 (37%), Positives = 36/83 (43%), Gaps = 16/83 (19%)

Query: 218  PQPQPPPQHPS--QPSAQSAPAPAQPAPQPPPAKVSKP-------------SQLQAHTPA 262
            P P PPP HPS  Q   Q  P P  P PQPPP +  +P             + +Q   P 
Sbjct: 955  PPPLPPPPHPSVQQQLQQQPPPPPPPQPQPPPQQQHQPPPRPVHLQPMQFSTHIQQPPPP 1014

Query: 263  SQQTPPLPPYASPRSPPVQPHTP 285
              Q PP PP    + PP QP  P
Sbjct: 1015 QGQQPPHPP-PGQQPPPPQPAKP 1036



 Score = 49.3 bits (116), Expect = 2e-05
 Identities = 33/97 (34%), Positives = 43/97 (44%), Gaps = 10/97 (10%)

Query: 209 HQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPP 268
           HQ       P PQ PP  P QP     P   Q  P PPP     PS  Q   PA + +P 
Sbjct: 743 HQQMQQAPAPVPQQPPPPPQQPPPPPPPQQQQQPPPPPP----PPSMPQQAAPAMKSSP- 797

Query: 269 LPPYASPRSPPVQPHTPVTI--SLG--TAPSLQNNQP 301
            PP+ + + P ++P  P ++   +G  T P L   QP
Sbjct: 798 -PPFIATQVPVLEPQLPGSVFDPIGHFTQPILHLPQP 833



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 74/294 (25%), Positives = 107/294 (36%), Gaps = 63/294 (21%)

Query: 23   STEAFPHQHRVLAPAPPVYEAVSETMQSATGIQYSVTPSYQVSAMPQSSG---SHGPAIA 79
            ST    +QH V++P P ++ A+          Q    PS + +A+P       +  PA+ 
Sbjct: 846  STPPHLNQHAVVSP-PALHNALP---------QQPSRPSNRAAALPPKPARPPAVSPALT 895

Query: 80   AVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQRL-KVEDALSYLDQVKLQFG 138
                    P A  P    +++    PAPP+  +Q Q   Q+L KV+     L  VK+Q  
Sbjct: 896  QTPLLPQPPMAQPPQ--VLLEDEEPPAPPLTSMQMQLYLQQLQKVQPPTPLLPSVKVQSQ 953

Query: 139  SQPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTFLPPGYKIEVQTND 198
              P +                  P     V Q  +  P          PP          
Sbjct: 954  PPPPL-----------------PPPPHPSVQQQLQQQPP---------PPPPPQPQPPPQ 987

Query: 199  MVNVTTPGQVH----QIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPS 254
              +   P  VH    Q  TH  QP   PPPQ       Q  P P  P  QPPP + +KP 
Sbjct: 988  QQHQPPPRPVHLQPMQFSTHIQQP---PPPQ------GQQPPHP-PPGQQPPPPQPAKPQ 1037

Query: 255  QL--QAHTPASQQTPPLPPYASPRSP-PVQPHTPVTISLGT----APSLQNNQP 301
            Q+    H+P   ++ P        +P P+  H+P      +    +P  QN QP
Sbjct: 1038 QVIQHHHSPRHHKSDPYSTGHLREAPSPLMIHSPQMSQFQSLTHQSPPQQNVQP 1091



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 30/85 (35%), Positives = 37/85 (43%), Gaps = 18/85 (21%)

Query: 221  QPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPV 280
            QPP   P  PS +    P  P P PP   V +  QL       QQ PP PP   P+ PP 
Sbjct: 939  QPPT--PLLPSVKVQSQPPPPLPPPPHPSVQQ--QL-------QQQPPPPPPPQPQPPPQ 987

Query: 281  QPHTPVTISLGTAPSLQNNQPVEFN 305
            Q H P        P   + QP++F+
Sbjct: 988  QQHQP-------PPRPVHLQPMQFS 1005



 Score = 40.0 bits (92), Expect = 0.014
 Identities = 38/118 (32%), Positives = 46/118 (38%), Gaps = 34/118 (28%)

Query: 205 PGQVHQIPTHGIQPQ------PQPP------PQHPSQPSAQSAPAPAQPAPQPPPAKVSK 252
           P  + Q P H   P         PP      PQ PS+PS ++A  P +PA  P       
Sbjct: 836 PPHLPQPPEHSTPPHLNQHAVVSPPALHNALPQQPSRPSNRAAALPPKPARPP------- 888

Query: 253 PSQLQAHTPASQQTP--PLPPYASP-------RSPPVQPHTPVTISLGTAPSLQNNQP 301
                A +PA  QTP  P PP A P         PP  P T + + L     LQ  QP
Sbjct: 889 -----AVSPALTQTPLLPQPPMAQPPQVLLEDEEPPAPPLTSMQMQL-YLQQLQKVQP 940



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 33/111 (29%), Positives = 36/111 (32%), Gaps = 39/111 (35%)

Query: 218 PQPQPPP----QHPSQ-----------------PSAQSAPAPAQPAPQPPPAKVSKPSQL 256
           PQP PPP     HP                   P     P P  P PQPPPA   +P  +
Sbjct: 211 PQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQPPPAPAPQP--V 268

Query: 257 QAHTPASQQTP---------------PLPPYASP-RSPPVQPHTPVTISLG 291
           Q+H P    TP                 P    P   PP  P  P T  LG
Sbjct: 269 QSHPPIIAATPQPVKTKKGVKRKADTTTPTTIDPIHEPPSLPPEPKTTKLG 319



 Score = 39.7 bits (91), Expect = 0.019
 Identities = 29/85 (34%), Positives = 34/85 (40%), Gaps = 7/85 (8%)

Query: 200 VNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAH 259
           V    P Q  Q P   + PQPQPPP    QP  QS P      PQP   K     +    
Sbjct: 238 VMTVVPPQPLQTPPP-VPPQPQPPPAPAPQP-VQSHPPIIAATPQPVKTKKGVKRKADTT 295

Query: 260 TPASQQTPPLPPYASPRSPPVQPHT 284
           TP +     + P   P S P +P T
Sbjct: 296 TPTT-----IDPIHEPPSLPPEPKT 315



 Score = 36.6 bits (83), Expect = 0.16
 Identities = 26/72 (36%), Positives = 30/72 (41%), Gaps = 6/72 (8%)

Query: 218 PQPQPPPQHPSQPSAQSAPAPAQPAP---QPPPAKVSKPSQLQAHTPASQQTPPLPPYAS 274
           PQ Q P  +P    A   P PA       Q P   V  P  LQ   P   Q  P PP  +
Sbjct: 206 PQTQTPQPNPPPVQATPHPFPAVTPDLIVQTPVMTVVPPQPLQTPPPVPPQPQP-PPAPA 264

Query: 275 PRSPPVQPHTPV 286
           P+  PVQ H P+
Sbjct: 265 PQ--PVQSHPPI 274


>gi|239757130 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 855

 Score = 51.2 bits (121), Expect = 6e-06
 Identities = 71/283 (25%), Positives = 98/283 (34%), Gaps = 27/283 (9%)

Query: 21  PGSTEAFPHQHRVLAPAPPVYEAVSETMQSATGIQYSVTPSYQVSAMPQSSGSH-GPAIA 79
           P  + +   +H    P+P    A      +  G+Q   + S   SA P SS +  GP+  
Sbjct: 205 PRKSVSSASEHSTTEPSP----AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR 260

Query: 80  AVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGS 139
               +  HP+  +P G Q ++      P V P        R     AL  L    L   S
Sbjct: 261 GTPRAPAHPSQPKPKGLQALRP-----PQVTP-------PRKDAAPALGPLSSSPLATPS 308

Query: 140 QPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTF-LPPGYKIEVQTND 198
                             S      ++    L    P       T   PP       T  
Sbjct: 309 PSAALQSQAPPTLPATPHSSSLTCQLATPLPLAPPSPSAPPSLQTLPSPPATPPSQATTS 368

Query: 199 MVNVTTPGQVHQIPTHGIQPQPQPPPQHP---SQPSAQSAPAPAQPAPQPPPAKVS--KP 253
           + + T       +P+  + P   PPPQ P   + P  Q+ P+P    P  P A  S   P
Sbjct: 369 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 428

Query: 254 SQLQAH-TPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPS 295
           + L  H   A    PP PP  +P SPP  P  PV+ S  T PS
Sbjct: 429 NALAVHLLQAPFSPPPSPPVQAPFSPPASP--PVSPS-ATPPS 468



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 31/90 (34%), Positives = 39/90 (43%), Gaps = 6/90 (6%)

Query: 212 PTHGIQPQPQPPPQHPSQPSA----QSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTP 267
           P+  +Q    PP   P  PSA    Q+ P+ A P  Q PP+  + P    + TP  Q  P
Sbjct: 444 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 503

Query: 268 PL--PPYASPRSPPVQPHTPVTISLGTAPS 295
           PL  PP    + PP  P    T  L   PS
Sbjct: 504 PLAAPPLQLAKPPPQAPPALATPPLQALPS 533



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 12/85 (14%)

Query: 218 PQPQPPPQHPSQPSAQSAPAP-AQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPR 276
           P P PP Q P  P A    +P A P  Q PP+  + P Q+    PAS   PP+ P A   
Sbjct: 442 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS---PPMSPSA--- 495

Query: 277 SPPVQPHTPVTISLGTAPSLQNNQP 301
           +PP Q   P+      AP LQ  +P
Sbjct: 496 TPPPQAPPPL-----AAPPLQLAKP 515



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 30/94 (31%), Positives = 39/94 (41%), Gaps = 12/94 (12%)

Query: 210 QIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQP---PPAKVSKPSQLQAHTPASQQT 266
           Q P     P  Q PP  P+ P    +  P   AP P   PP +++KP       P +  T
Sbjct: 469 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP---PPQAPPALAT 525

Query: 267 PPL-----PPYASPRSPPVQPHTPVTIS-LGTAP 294
           PPL     PP + P   P  P   + +S L T P
Sbjct: 526 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 559



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 32/84 (38%), Positives = 37/84 (44%), Gaps = 4/84 (4%)

Query: 216 IQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPAS--QQTPPLPPYA 273
           + P   PPPQ P  P A      A+P PQ PPA  + P Q     PAS   Q P  P  +
Sbjct: 491 MSPSATPPPQAP-PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 549

Query: 274 SPRSPPVQPHTPVTISLGTAPSLQ 297
            P SP   P  P    +  AP LQ
Sbjct: 550 LPMSPLATP-PPQAPPVLAAPLLQ 572



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 29/85 (34%), Positives = 37/85 (43%), Gaps = 4/85 (4%)

Query: 218 PQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRS 277
           P P  PP   + PS Q+ P+P  PA  P  A  S  S     T +   +PPL P A+P  
Sbjct: 337 PLPLAPPSPSAPPSLQTLPSP--PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP-- 392

Query: 278 PPVQPHTPVTISLGTAPSLQNNQPV 302
           PP  P       L   PS   + P+
Sbjct: 393 PPQAPPALALPPLQAPPSPPASPPL 417



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 6/73 (8%)

Query: 216 IQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPP----AKVSKPSQLQAHTPASQQTPPL-- 269
           + P   P PQ P+  +     AP  P P PP     +  + P    + TP SQ  P L  
Sbjct: 417 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 476

Query: 270 PPYASPRSPPVQP 282
           PP   P SPP  P
Sbjct: 477 PPLQVPPSPPASP 489



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 30/105 (28%), Positives = 38/105 (36%), Gaps = 22/105 (20%)

Query: 212 PTHGIQPQPQPPP-------------------QHPSQPSAQSAPAP-AQPAPQPPPAKVS 251
           P    +P PQ PP                   Q P  PSA    +P A P PQ PP   +
Sbjct: 509 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 568

Query: 252 KPSQLQAHTPASQ--QTPPLPPYASPRSPPVQPHTPVTISLGTAP 294
              Q+    PAS   Q P  PP   P +    P   + ++ G  P
Sbjct: 569 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 613



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 25/68 (36%), Positives = 28/68 (41%), Gaps = 7/68 (10%)

Query: 210 QIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPL 269
           Q P     P  Q PP  P+ P+ Q   AP +P    P   VS P    A  P     PP 
Sbjct: 561 QAPPVLAAPLLQVPPSPPASPTLQ---APRRPPTPGPDTSVSGPRLTLALAPG----PPP 613

Query: 270 PPYASPRS 277
           PP  SP S
Sbjct: 614 PPSRSPSS 621


>gi|38788260 bromodomain PHD finger transcription factor isoform 2
            [Homo sapiens]
          Length = 2903

 Score = 50.8 bits (120), Expect = 8e-06
 Identities = 45/193 (23%), Positives = 75/193 (38%), Gaps = 18/193 (9%)

Query: 193  EVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSK 252
            EVQT   V+   P +    PTH    +PQ   Q   Q + Q        +P     + S 
Sbjct: 2424 EVQTQTTVSSHVPSEAQ--PTHAQSSKPQVAAQSQPQSNVQGQSPVRVQSPSQTRIRPST 2481

Query: 253  PSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQPVEFNHAINYVN 312
            PSQL     +  QT    P       P+QPHT + I     P  Q    ++ N  I ++ 
Sbjct: 2482 PSQLSPGQQSQVQTTTSQPI------PIQPHTSLQIPSQGQPQSQPQVVMKHNAVIEHLK 2535

Query: 313  KIKNRFQGQPD----------IYKAFLEILHTYQKEQRNAKEAGGNYTPALTEQEVYAQV 362
            + K+    + +          + K  L+ +   +K+    ++   +     ++Q      
Sbjct: 2536 QKKSMTPAEREENQRMIVCNQVMKYILDKIDKEEKQAAKKRKREESVEQKRSKQNATKLS 2595

Query: 363  ARLFKNQEDLLSE 375
            A LFK++E L +E
Sbjct: 2596 ALLFKHKEQLRAE 2608



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 23/81 (28%), Positives = 35/81 (43%), Gaps = 14/81 (17%)

Query: 223 PPQHPSQPSAQS-APAPAQPAPQPPPAKV------------SKPSQLQAH-TPASQQTPP 268
           PP+ P+ P+A+  APAP  P P P    +             + +  QA   P ++ + P
Sbjct: 8   PPKQPAAPAAERCAPAPPPPPPPPTSGPIGGLRSRHRGSSRGRWAAAQAEVAPKTRLSSP 67

Query: 269 LPPYASPRSPPVQPHTPVTIS 289
               +S R PP  P  P + S
Sbjct: 68  RGGSSSRRKPPPPPPAPPSTS 88


>gi|4826998 splicing factor proline/glutamine rich (polypyrimidine
           tract binding protein associated) [Homo sapiens]
          Length = 707

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 37/104 (35%), Positives = 41/104 (39%), Gaps = 14/104 (13%)

Query: 209 HQIPTHGI---QPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQ 265
           HQ P H     Q QP PPPQ  S+P     P PA      PPA  S P    A  P S  
Sbjct: 85  HQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAP---PATPPTSGA 141

Query: 266 TP-------PLPPYASPRSPP-VQPHTPVTISLGTAPSLQNNQP 301
            P       P PP A   +PP   P TP +  + T P      P
Sbjct: 142 PPGSGPGPTPTPPPAVTSAPPGAPPPTPPSSGVPTTPPQAGGPP 185



 Score = 45.1 bits (105), Expect = 4e-04
 Identities = 37/116 (31%), Positives = 43/116 (37%), Gaps = 19/116 (16%)

Query: 187 PPGYKIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAP-QP 245
           PPG  +      M     PGQ    P     P P PPP    Q      P P QP P QP
Sbjct: 35  PPGMGLNQNRGPMG--PGPGQSGPKP-----PIPPPPPHQQQQQPPPQQPPPQQPPPHQP 87

Query: 246 PPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSLQNNQP 301
           PP             P  QQ PP PP  S +    Q   P    +G+AP   ++ P
Sbjct: 88  PPHP----------QPHQQQQPPPPPQDSSKPVVAQGPGPAP-GVGSAPPASSSAP 132



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 29/75 (38%), Positives = 30/75 (40%), Gaps = 8/75 (10%)

Query: 217 QPQPQPPPQHPSQPSAQSAPAPAQP----APQPPPAKVSKPSQLQAHTPAS--QQTPPLP 270
           QP PQ PP  P QP     P   QP     P PPP   SKP   Q   PA      PP  
Sbjct: 71  QPPPQQPP--PQQPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPAS 128

Query: 271 PYASPRSPPVQPHTP 285
             A P +PP     P
Sbjct: 129 SSAPPATPPTSGAPP 143



 Score = 44.3 bits (103), Expect = 8e-04
 Identities = 26/86 (30%), Positives = 31/86 (36%), Gaps = 8/86 (9%)

Query: 217 QPQPQPPPQHPSQPSAQSAPAPAQPA--------PQPPPAKVSKPSQLQAHTPASQQTPP 268
           QP P  PP HP     Q  P P Q +        P P P   S P    +  PA+  T  
Sbjct: 81  QPPPHQPPPHPQPHQQQQPPPPPQDSSKPVVAQGPGPAPGVGSAPPASSSAPPATPPTSG 140

Query: 269 LPPYASPRSPPVQPHTPVTISLGTAP 294
            PP + P   P  P    +   G  P
Sbjct: 141 APPGSGPGPTPTPPPAVTSAPPGAPP 166



 Score = 39.3 bits (90), Expect = 0.024
 Identities = 27/75 (36%), Positives = 28/75 (37%), Gaps = 6/75 (8%)

Query: 205 PGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQ 264
           PG V   P       P  PP   + P   S P    P P PPPA  S P      TP S 
Sbjct: 119 PG-VGSAPPASSSAPPATPPTSGAPPG--SGPG---PTPTPPPAVTSAPPGAPPPTPPSS 172

Query: 265 QTPPLPPYASPRSPP 279
             P  PP A    PP
Sbjct: 173 GVPTTPPQAGGPPPP 187



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 25/68 (36%), Positives = 27/68 (39%), Gaps = 8/68 (11%)

Query: 212 PTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPP 271
           PT G  P   P P     P+  SAP P  P P PP + V         TP     PP PP
Sbjct: 137 PTSGAPPGSGPGPTPTPPPAVTSAP-PGAPPPTPPSSGVPT-------TPPQAGGPPPPP 188

Query: 272 YASPRSPP 279
            A P   P
Sbjct: 189 AAVPGPGP 196


>gi|18959210 WIRE protein [Homo sapiens]
          Length = 440

 Score = 50.4 bits (119), Expect = 1e-05
 Identities = 34/111 (30%), Positives = 46/111 (41%), Gaps = 29/111 (26%)

Query: 195 QTNDMVNVTTPGQVHQIPTHGIQPQP-----------QPPPQHPSQPSAQSAPAPAQP-- 241
           Q ++ ++  TPG     P  G+ P P           +PPP     PS  +AP P  P  
Sbjct: 278 QRHNSLHRKTPG-----PVRGLAPPPPTSASPSLLSNRPPPPARDPPSRGAAPPPPPPVI 332

Query: 242 ------APQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPV 286
                 AP PPP     P ++    P S+  PP PP  +P  PP  P  P+
Sbjct: 333 RNGARDAPPPPP-----PYRMHGSEPPSRGKPPPPPSRTPAGPPPPPPPPL 378



 Score = 43.1 bits (100), Expect = 0.002
 Identities = 30/94 (31%), Positives = 36/94 (38%), Gaps = 15/94 (15%)

Query: 220 PQPPPQHPSQPSAQSAPAPAQPAP------------QPPPAKVSKPSQLQAHTPASQQT- 266
           P P P H S+  A +   P  P P             PPP K   PS +   T  S Q+ 
Sbjct: 190 PTPLPMHSSKAPAYNREKPLPPTPGQRLHPGREGPPAPPPVK-PPPSPVNIRTGPSGQSL 248

Query: 267 -PPLPPYASPRSPPVQPHTPVTISLGTAPSLQNN 299
            PP PPY  P   P  P +P   S    P   N+
Sbjct: 249 APPPPPYRQPPGVPNGPSSPTNESAPELPQRHNS 282



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 27/95 (28%), Positives = 40/95 (42%), Gaps = 16/95 (16%)

Query: 222 PPPQHPSQPSAQSAPAPAQPAPQPPPAKVSK--PSQLQAHT---PASQQTPPLPPYAS-- 274
           P    P+  S+      +   P PPP + +   P+ L  H+   PA  +  PLPP     
Sbjct: 157 PDLSRPNTTSSTGMKHSSSAPPPPPPGRRANAPPTPLPMHSSKAPAYNREKPLPPTPGQR 216

Query: 275 --------PRSPPVQPHTPVTISLGTAPSLQNNQP 301
                   P  PPV+P  P  +++ T PS Q+  P
Sbjct: 217 LHPGREGPPAPPPVKP-PPSPVNIRTGPSGQSLAP 250



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 26/101 (25%), Positives = 38/101 (37%), Gaps = 8/101 (7%)

Query: 187 PPGYKIEVQTNDMVNVTTPG-----QVHQIPTHGIQPQPQPPPQHPSQPSA--QSAPAPA 239
           PP   + ++T        P      Q   +P     P  +  P+ P + ++  +  P P 
Sbjct: 232 PPPSPVNIRTGPSGQSLAPPPPPYRQPPGVPNGPSSPTNESAPELPQRHNSLHRKTPGPV 291

Query: 240 QPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPV 280
           +    PPP   S PS L    P   + PP    A P  PPV
Sbjct: 292 RGLAPPPPTSAS-PSLLSNRPPPPARDPPSRGAAPPPPPPV 331


>gi|148596988 mucoepidermoid carcinoma translocated 1 isoform 3
           [Homo sapiens]
          Length = 650

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 34/89 (38%), Positives = 41/89 (46%), Gaps = 17/89 (19%)

Query: 218 PQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSK-----PSQLQAHTPASQQTPPLP-- 270
           PQPQPPP  P        PA  QP P PPP    +     P    A      Q PPL   
Sbjct: 381 PQPQPPPPPP--------PASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVT 432

Query: 271 -PYASPRSPPVQPHTP-VTISLGTAPSLQ 297
            P + P+SPP  P  P + I + +AP+LQ
Sbjct: 433 VPSSLPQSPPENPGQPSMGIDIASAPALQ 461



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 26/65 (40%), Positives = 30/65 (46%), Gaps = 14/65 (21%)

Query: 232 AQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASP-RSPPVQPHTP-VTIS 289
           A S   P QP P PPP             PASQQ PP PP  +P R PP  P  P  +++
Sbjct: 374 AGSQQPPPQPQPPPPP------------PPASQQPPPPPPPQAPVRLPPGGPLLPSASLT 421

Query: 290 LGTAP 294
            G  P
Sbjct: 422 RGPQP 426



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 27/99 (27%), Positives = 34/99 (34%), Gaps = 9/99 (9%)

Query: 202 VTTPGQVHQIPTHGIQP---------QPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSK 252
           ++TPG   Q    G+ P         Q   P   P  P  Q+    A    Q  P     
Sbjct: 313 MSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFT 372

Query: 253 PSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLG 291
            +  Q   P  Q  PP PP +    PP  P  PV +  G
Sbjct: 373 QAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPG 411


>gi|148596965 mucoepidermoid carcinoma translocated 1 isoform 1
           [Homo sapiens]
          Length = 634

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 34/89 (38%), Positives = 41/89 (46%), Gaps = 17/89 (19%)

Query: 218 PQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSK-----PSQLQAHTPASQQTPPLP-- 270
           PQPQPPP  P        PA  QP P PPP    +     P    A      Q PPL   
Sbjct: 365 PQPQPPPPPP--------PASQQPPPPPPPQAPVRLPPGGPLLPSASLTRGPQPPPLAVT 416

Query: 271 -PYASPRSPPVQPHTP-VTISLGTAPSLQ 297
            P + P+SPP  P  P + I + +AP+LQ
Sbjct: 417 VPSSLPQSPPENPGQPSMGIDIASAPALQ 445



 Score = 38.1 bits (87), Expect = 0.054
 Identities = 26/65 (40%), Positives = 30/65 (46%), Gaps = 14/65 (21%)

Query: 232 AQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASP-RSPPVQPHTP-VTIS 289
           A S   P QP P PPP             PASQQ PP PP  +P R PP  P  P  +++
Sbjct: 358 AGSQQPPPQPQPPPPP------------PPASQQPPPPPPPQAPVRLPPGGPLLPSASLT 405

Query: 290 LGTAP 294
            G  P
Sbjct: 406 RGPQP 410



 Score = 37.0 bits (84), Expect = 0.12
 Identities = 27/99 (27%), Positives = 34/99 (34%), Gaps = 9/99 (9%)

Query: 202 VTTPGQVHQIPTHGIQP---------QPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSK 252
           ++TPG   Q    G+ P         Q   P   P  P  Q+    A    Q  P     
Sbjct: 297 MSTPGSSPQHRPAGVSPLSLSTEARRQQASPTLSPLSPITQAVAMDALSLEQQLPYAFFT 356

Query: 253 PSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLG 291
            +  Q   P  Q  PP PP +    PP  P  PV +  G
Sbjct: 357 QAGSQQPPPQPQPPPPPPPASQQPPPPPPPQAPVRLPPG 395


>gi|51702526 Wiskott-Aldrich syndrome gene-like protein [Homo
           sapiens]
          Length = 505

 Score = 49.7 bits (117), Expect = 2e-05
 Identities = 34/85 (40%), Positives = 38/85 (44%), Gaps = 9/85 (10%)

Query: 218 PQPQPPPQH---PSQPSAQSAPAPAQP---AP--QPPPAKVSKPSQLQAHTPASQQTPPL 269
           P P PPP H   P  P A+   AP  P   AP   PPP   S+PS      P ++  PP 
Sbjct: 287 PPPPPPPPHNSGPPPPPARGRGAPPPPPSRAPTAAPPPPPPSRPSVAVPPPPPNRMYPP- 345

Query: 270 PPYASPRSPPVQPHTPVTISLGTAP 294
           PP A P S P  P  P    LG  P
Sbjct: 346 PPPALPSSAPSGPPPPPPSVLGVGP 370



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 29/75 (38%), Positives = 32/75 (42%), Gaps = 7/75 (9%)

Query: 218 PQPQPPPQHPSQPS-AQSAPAPAQPAPQPPPA-KVSKPSQLQAHTPA-----SQQTPPLP 270
           P   PPP  PS+PS A   P P +  P PPPA   S PS      P+         PP P
Sbjct: 318 PTAAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPPPPPSVLGVGPVAPPPPP 377

Query: 271 PYASPRSPPVQPHTP 285
           P   P  PP  P  P
Sbjct: 378 PPPPPPGPPPPPGLP 392



 Score = 38.9 bits (89), Expect = 0.032
 Identities = 25/80 (31%), Positives = 35/80 (43%), Gaps = 8/80 (10%)

Query: 212 PTHGIQPQPQPPPQHPSQPSAQSAPAPAQPA---PQPPPAKVSKPSQLQAHTPASQQTPP 268
           P  G    P PP + P+  +A   P P++P+   P PPP ++  P      + A    PP
Sbjct: 303 PARGRGAPPPPPSRAPT--AAPPPPPPSRPSVAVPPPPPNRMYPPPPPALPSSAPSGPPP 360

Query: 269 LPPY---ASPRSPPVQPHTP 285
            PP      P +PP  P  P
Sbjct: 361 PPPSVLGVGPVAPPPPPPPP 380


>gi|126090663 zinc finger homeodomain 4 [Homo sapiens]
          Length = 3571

 Score = 48.9 bits (115), Expect = 3e-05
 Identities = 35/91 (38%), Positives = 40/91 (43%), Gaps = 13/91 (14%)

Query: 220  PQPPPQHPSQPSAQSAPAPAQPAPQPP---PAKVSKPSQLQAHTPASQQTPPLPPYASPR 276
            P PPP  P  P     PAP QP+   P   P  VS P Q    TP     PP PP   P 
Sbjct: 1958 PPPPPPPPPLP-----PAPPQPSSMGPVKIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPP 2012

Query: 277  SP----PVQPHTPVTISLGTAPSLQNNQPVE 303
             P    P Q   PV++ L   PS+   QPV+
Sbjct: 2013 PPPPSAPPQVQLPVSLDLPLFPSIM-MQPVQ 2042



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 31/95 (32%), Positives = 44/95 (46%), Gaps = 13/95 (13%)

Query: 217  QPQPQ---PPPQHPSQPSAQSAPAPAQPAPQP--PPAKVSK-PSQLQAHTPASQQTPPLP 270
            +P+P+   P P++P++   QS P+P     +P  P A  S  P Q     P  Q  PP  
Sbjct: 2351 KPEPEKTSPKPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQ 2410

Query: 271  PYASPRSPPVQ----PHTPVTISLGTAPSLQNNQP 301
            P    R P       P +P+ IS+    SLQN+ P
Sbjct: 2411 PQLIGRPPSASQTPVPSSPLQISM---TSLQNSLP 2442



 Score = 37.7 bits (86), Expect = 0.071
 Identities = 35/126 (27%), Positives = 44/126 (34%), Gaps = 17/126 (13%)

Query: 193  EVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVS- 251
            E QT D ++ T    V++  T   Q         P+  S      P  P+P+P P K S 
Sbjct: 2301 ESQTEDSMDATDQ-VVYKHCTVSGQTDAAKNAAAPAASSGSGTSTPLIPSPKPEPEKTSP 2359

Query: 252  -------KPSQLQAHTPASQQTPPL--------PPYASPRSPPVQPHTPVTISLGTAPSL 296
                   KP Q     P+    P L        PP AS   P  QP  P    L   P  
Sbjct: 2360 KPEYPAEKPKQSDPSPPSQGTKPALPLASTSSDPPQASTAQPQPQPQPPKQPQLIGRPPS 2419

Query: 297  QNNQPV 302
             +  PV
Sbjct: 2420 ASQTPV 2425



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 82/343 (23%), Positives = 120/343 (34%), Gaps = 56/343 (16%)

Query: 77   AIAAVHSSHHHPTAVQPHGGQVVQS-HAHPA--PPVAPVQGQQQFQRLKVEDALSYLDQV 133
            ++AAV+S   H  A + +  Q      A PA  PP +P Q Q Q Q    + A  +    
Sbjct: 1609 SLAAVNSKDTHLDAKELNKKQTPDLISAQPAHHPPQSPAQIQMQLQHELQQQAAFF---- 1664

Query: 134  KLQFGSQPQVYND-FL-------DIMKEFKSQSIDTPGVISRVSQLFKGHPDL-IMGFNT 184
                  QPQ  N  FL       + + +F+      P  I      F   PDL + G  T
Sbjct: 1665 ------QPQFLNPAFLPHFPMTPEALLQFQQPQFLFPFYIPGTE--FSLGPDLGLPGSAT 1716

Query: 185  FLPPGY-----------KIEVQTNDMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQ 233
            F  PG            K ++QT   V  T    + Q        QPQ  PQ       Q
Sbjct: 1717 FGMPGMTGMAGSLLEDLKQQIQTQHHVGQTQLQILQQQAQQYQATQPQLQPQ-----KQQ 1771

Query: 234  SAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTA 293
              P P Q   Q   +K+ K  Q    +   Q    +P Y        +P  P    +   
Sbjct: 1772 QQPPPPQQQQQQQASKLLKQEQSNIVSADCQIMKDVPSYKEAEDISEKPEKPKQEFISEG 1831

Query: 294  PSLQNNQPVEFNHAIN-YVNKIKNRFQGQPDIYKAFLEIL---------HTYQKEQRNAK 343
              L+  +  +   ++   +   +     + +  KA LE              QK Q+  K
Sbjct: 1832 EGLKEGKDTKKQKSLEPSIPPPRIASGARGNAAKALLENFGFELVIQYNENRQKVQKKGK 1891

Query: 344  EAGGNYTPAL---TEQEVYAQVARLFKNQEDLLSEFGQFLPDA 383
               G  T  L   T  ++++ V  L  +QE +    GQF P A
Sbjct: 1892 SGEGENTDKLECGTCGKLFSNVLILKSHQEHV---HGQFFPYA 1931



 Score = 34.3 bits (77), Expect = 0.78
 Identities = 25/75 (33%), Positives = 27/75 (36%), Gaps = 12/75 (16%)

Query: 210  QIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPL 269
            +IP     P   PPP  P  P     P P  P P P     S P Q+Q   P S   P  
Sbjct: 1981 KIPNTVSTPLQAPPPTPPPPPPPPPPPPPPPPPPPP-----SAPPQVQ--LPVSLDLPLF 2033

Query: 270  P-----PYASPRSPP 279
            P     P   P  PP
Sbjct: 2034 PSIMMQPVQHPALPP 2048



 Score = 33.5 bits (75), Expect = 1.3
 Identities = 27/98 (27%), Positives = 35/98 (35%), Gaps = 14/98 (14%)

Query: 212  PTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPP 271
            P      QPQP PQ P QP     P  A   P P     S P Q+   +  +   P L  
Sbjct: 2393 PPQASTAQPQPQPQPPKQPQLIGRPPSASQTPVP-----SSPLQISMTSLQNSLPPQLLQ 2447

Query: 272  YASPRSPPVQPHTPVTISLGTAPSLQNNQPVEFNHAIN 309
            Y   +          T++  T    Q +Q + F  A N
Sbjct: 2448 YQCDQ---------CTVAFPTLELWQEHQHMHFLAAQN 2476


>gi|239751637 PREDICTED: hypothetical protein FLJ22184 [Homo
           sapiens]
          Length = 1124

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 29/77 (37%), Positives = 36/77 (46%), Gaps = 6/77 (7%)

Query: 212 PTHGIQPQPQPPPQHPSQPSA----QSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTP 267
           P+  +Q    PP   P  PSA    Q+ P+ A P  Q PP+  + P    + TP  Q  P
Sbjct: 669 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 728

Query: 268 PL--PPYASPRSPPVQP 282
           PL  PP   P SPP  P
Sbjct: 729 PLAAPPLQVPPSPPASP 745



 Score = 47.4 bits (111), Expect = 9e-05
 Identities = 30/94 (31%), Positives = 41/94 (43%), Gaps = 9/94 (9%)

Query: 215 GIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYAS 274
           G + +P PPP + + P   + P P+ P   P P     PS      P S QT P PP   
Sbjct: 311 GTKARPVPPPDNAATPLPATLP-PSPPLATPLPLAPPSPS-----APPSLQTLPSPPATP 364

Query: 275 PRSPPVQPHTPVTISLGTAPSLQNNQPVEFNHAI 308
           P   P    TP    +   PSLQ   P++  H++
Sbjct: 365 PSQAPPSMTTP---PMQAPPSLQTIPPIQVPHSL 395



 Score = 46.6 bits (109), Expect = 2e-04
 Identities = 31/86 (36%), Positives = 39/86 (45%), Gaps = 6/86 (6%)

Query: 218 PQPQPPPQHPSQPSAQSAPAP-AQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPR 276
           P P PP Q P  P A    +P A P  Q PP+  + P Q+    PAS   PP+ P A+P 
Sbjct: 667 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS---PPMSPSATP- 722

Query: 277 SPPVQPHTPVTISLGTAPSLQNNQPV 302
            PP  P       L   PS   + P+
Sbjct: 723 -PPQAPPPLAAPPLQVPPSPPASPPM 747



 Score = 46.2 bits (108), Expect = 2e-04
 Identities = 30/93 (32%), Positives = 39/93 (41%), Gaps = 14/93 (15%)

Query: 216 IQPQPQPPPQHPSQPSA----QSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQ------- 264
           +Q  P PP   P  PSA    Q+ P  A P  Q PP+  + P    + TP  +       
Sbjct: 704 LQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQVPPSPPASPPMSPSATPPPRVPPLLAA 763

Query: 265 ---QTPPLPPYASPRSPPVQPHTPVTISLGTAP 294
              Q PP PP + P SP  +P      +L T P
Sbjct: 764 PPLQVPPSPPASLPMSPLAKPPPQAPPALATPP 796



 Score = 45.8 bits (107), Expect = 3e-04
 Identities = 34/91 (37%), Positives = 43/91 (47%), Gaps = 9/91 (9%)

Query: 211 IPTHGIQPQPQPPPQHP---SQPSAQSAPAPAQPAPQPPPAKVS--KPSQLQAH-TPASQ 264
           +P+  + P   PPPQ P   + P  Q+ P+P    P  P A  S   P+ L  H   A  
Sbjct: 606 LPSPPLSPLATPPPQAPPXLALPPLQAPPSPPASPPLSPLATPSPQAPNALAVHLLQAPF 665

Query: 265 QTPPLPPYASPRSPPVQPHTPVTISLGTAPS 295
             PP PP  +P SPP  P  PV+ S  T PS
Sbjct: 666 SPPPSPPVQAPFSPPASP--PVSPS-ATPPS 693



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 27/71 (38%), Positives = 32/71 (45%), Gaps = 9/71 (12%)

Query: 221 QPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPAS------QQTPP---LPP 271
           Q PP   + P  ++  + A P PQ PPA  S P Q     P S       Q PP   LPP
Sbjct: 570 QAPPSPLTTPPPETPSSIATPPPQAPPALASPPLQGLPSPPLSPLATPPPQAPPXLALPP 629

Query: 272 YASPRSPPVQP 282
             +P SPP  P
Sbjct: 630 LQAPPSPPASP 640



 Score = 43.5 bits (101), Expect = 0.001
 Identities = 30/89 (33%), Positives = 39/89 (43%), Gaps = 8/89 (8%)

Query: 210 QIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPL 269
           Q P     P  Q PP  P+ P    +   A P PQ PP   + P Q+    PAS   PP+
Sbjct: 694 QAPPSLAAPPLQVPPSPPASPPMSPS---ATPPPQAPPPLAAPPLQVPPSPPAS---PPM 747

Query: 270 PPYAS--PRSPPVQPHTPVTISLGTAPSL 296
            P A+  PR PP+    P+ +      SL
Sbjct: 748 SPSATPPPRVPPLLAAPPLQVPPSPPASL 776



 Score = 41.2 bits (95), Expect = 0.006
 Identities = 25/73 (34%), Positives = 31/73 (42%), Gaps = 6/73 (8%)

Query: 216 IQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPP----AKVSKPSQLQAHTPASQQTPPL-- 269
           + P   P PQ P+  +     AP  P P PP     +  + P    + TP SQ  P L  
Sbjct: 642 LSPLATPSPQAPNALAVHLLQAPFSPPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAA 701

Query: 270 PPYASPRSPPVQP 282
           PP   P SPP  P
Sbjct: 702 PPLQVPPSPPASP 714



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 31/86 (36%), Positives = 38/86 (44%), Gaps = 15/86 (17%)

Query: 216 IQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPL---PPY 272
           +Q  P PP   P  PS       A P P+ PP   + P Q+    PAS    PL   PP 
Sbjct: 735 LQVPPSPPASPPMSPS-------ATPPPRVPPLLAAPPLQVPPSPPASLPMSPLAKPPPQ 787

Query: 273 ASP--RSPPVQ--PHTPVTISLGTAP 294
           A P   +PP+Q  P  P +   G AP
Sbjct: 788 APPALATPPLQALPSPPASFP-GQAP 812



 Score = 40.8 bits (94), Expect = 0.008
 Identities = 31/79 (39%), Positives = 36/79 (45%), Gaps = 4/79 (5%)

Query: 222 PPPQHPSQPSAQSAPAP-AQPAPQPPPAKVSKPSQLQAHTPAS--QQTPPLPPYASPRSP 278
           PP Q P  P A    +P A+P PQ PPA  + P Q     PAS   Q P  P  + P SP
Sbjct: 764 PPLQVPPSPPASLPMSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSP 823

Query: 279 PVQPHTPVTISLGTAPSLQ 297
              P  P    +  AP LQ
Sbjct: 824 LATP-PPQAPPVLAAPLLQ 841



 Score = 37.4 bits (85), Expect = 0.092
 Identities = 70/303 (23%), Positives = 101/303 (33%), Gaps = 59/303 (19%)

Query: 21  PGSTEAFPHQHRVLAPAPPVYEAVSETMQSATGIQYSVTPSYQVSAMPQSSGSH-GPAIA 79
           P  + +   +H    P+P    A      +  G+Q   + S   SA P SS +  GP+  
Sbjct: 205 PRKSVSSASEHSTTEPSP----AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR 260

Query: 80  AVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGS 139
               +  HP+  +P G Q ++      P V P        R     AL  L    L   S
Sbjct: 261 GTPRAPAHPSQPKPKGLQALRP-----PQVTP-------PRKDAAPALGPLSSSPLATPS 308

Query: 140 QPQVYNDFLDIMKEFKSQSIDTP-GVISRVSQLFKGHPDLIMGFNTFLP-PGYKIEVQTN 197
                          K++ +  P    + +       P L        P P     +QT 
Sbjct: 309 PSGT-----------KARPVPPPDNAATPLPATLPPSPPLATPLPLAPPSPSAPPSLQTL 357

Query: 198 DMVNVTTPGQVHQIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQ 257
                T P Q    P     P  Q PP   + P  Q   +   P+ Q PP+ ++  S LQ
Sbjct: 358 PSPPATPPSQA---PPSMTTPPMQAPPSLQTIPPIQVPHSLTSPSLQAPPSPLAL-SSLQ 413

Query: 258 A---------------------HTPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPSL 296
           A                      T AS  +P  P    P SPP+Q      +SL  +P L
Sbjct: 414 ATTSLGSPTLQATHSFLTMSPRQTQASLTSPSRPASTPPDSPPLQ----APLSLPASPPL 469

Query: 297 QNN 299
           Q +
Sbjct: 470 QTS 472



 Score = 35.8 bits (81), Expect = 0.27
 Identities = 28/105 (26%), Positives = 39/105 (37%), Gaps = 26/105 (24%)

Query: 216 IQPQPQPPPQHP---SQPSAQSAPAP---------------------AQPAPQPPPAKVS 251
           + P  +PPPQ P   + P  Q+ P+P                     A P PQ PP   +
Sbjct: 778 MSPLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 837

Query: 252 KPSQLQAHTPASQ--QTPPLPPYASPRSPPVQPHTPVTISLGTAP 294
              Q+    PAS   Q P  PP   P +    P   + ++ G  P
Sbjct: 838 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 882



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 25/68 (36%), Positives = 28/68 (41%), Gaps = 7/68 (10%)

Query: 210 QIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPL 269
           Q P     P  Q PP  P+ P+ Q   AP +P    P   VS P    A  P     PP 
Sbjct: 830 QAPPVLAAPLLQVPPSPPASPTLQ---APRRPPTPGPDTSVSGPRLTLALAPG----PPP 882

Query: 270 PPYASPRS 277
           PP  SP S
Sbjct: 883 PPSRSPSS 890



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 25/88 (28%), Positives = 36/88 (40%), Gaps = 11/88 (12%)

Query: 224 PQHPSQPSAQSAPAPAQPAPQPPPAKVSKP-------SQLQAHTPASQQTPPLP---PYA 273
           P HPSQP  +   A  +P    PP K + P       S L   +P+  +  P+P     A
Sbjct: 266 PAHPSQPKPKGLQA-LRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTKARPVPPPDNAA 324

Query: 274 SPRSPPVQPHTPVTISLGTAPSLQNNQP 301
           +P    + P  P+   L  AP   +  P
Sbjct: 325 TPLPATLPPSPPLATPLPLAPPSPSAPP 352



 Score = 32.3 bits (72), Expect = 3.0
 Identities = 23/80 (28%), Positives = 32/80 (40%), Gaps = 12/80 (15%)

Query: 218 PQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLP---PYAS 274
           P  Q PP   + P  ++ P+ A     PPP + +       H     +TPP P   P  +
Sbjct: 521 PSLQTPPASLTTPPLENLPSLA-----PPPLQTASAPLTTPHL----ETPPCPAPCPLQA 571

Query: 275 PRSPPVQPHTPVTISLGTAP 294
           P SP   P      S+ T P
Sbjct: 572 PPSPLTTPPPETPSSIATPP 591



 Score = 32.0 bits (71), Expect = 3.9
 Identities = 33/102 (32%), Positives = 42/102 (41%), Gaps = 18/102 (17%)

Query: 203 TTPGQVHQIPTHGIQPQPQPPPQHPSQP------SAQSAPAPAQPAPQPPPAKVSKPSQL 256
           T P  +   P   +     PP Q  S P           PAP     Q PP+ ++ P   
Sbjct: 525 TPPASLTTPPLENLPSLAPPPLQTASAPLTTPHLETPPCPAPCPL--QAPPSPLTTP--- 579

Query: 257 QAHTPASQQTPPLPPYASP--RSPPVQ--PHTPVTISLGTAP 294
              TP+S  TP  PP A P   SPP+Q  P  P++  L T P
Sbjct: 580 PPETPSSIATP--PPQAPPALASPPLQGLPSPPLS-PLATPP 618



 Score = 31.6 bits (70), Expect = 5.1
 Identities = 27/90 (30%), Positives = 35/90 (38%), Gaps = 16/90 (17%)

Query: 228 SQPSAQSAP-APAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYAS------------ 274
           S PSA+  P APA P+ QP P  +      Q   P     P L P +S            
Sbjct: 255 SGPSARGTPRAPAHPS-QPKPKGLQALRPPQVTPPRKDAAPALGPLSSSPLATPSPSGTK 313

Query: 275 --PRSPPVQPHTPVTISLGTAPSLQNNQPV 302
             P  PP    TP+  +L  +P L    P+
Sbjct: 314 ARPVPPPDNAATPLPATLPPSPPLATPLPL 343


>gi|4557317 annexin A11 [Homo sapiens]
          Length = 505

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 35/95 (36%), Positives = 41/95 (43%), Gaps = 14/95 (14%)

Query: 205 PGQVHQIPTHGIQPQP--QPPPQHPSQPSAQSAPAPAQPAP----QPPPA-----KVSKP 253
           P     +P +G+ P P   PP + PS P    AP P QP P    QPP A      V+ P
Sbjct: 94  PSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYP 153

Query: 254 SQLQAHTPASQQTPPLPPYAS-PRSPPVQPHTPVT 287
            Q     P  QQ  P+P Y   P S  V P  P T
Sbjct: 154 GQPPVPLPGQQQ--PVPSYPGYPGSGTVTPAVPPT 186



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 29/86 (33%), Positives = 30/86 (34%), Gaps = 10/86 (11%)

Query: 220 PQPPPQHPSQPSAQSAPAP----AQPAPQPPPAKVSKPSQLQAHTPASQQTPP--LPPYA 273
           P PP      PSAQ    P      P   PP    S P    A  P     PP   PP A
Sbjct: 84  PVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGA 143

Query: 274 SPRSPPV----QPHTPVTISLGTAPS 295
            P  PPV    QP  P+       PS
Sbjct: 144 YPGQPPVTYPGQPPVPLPGQQQPVPS 169


>gi|22165433 annexin A11 [Homo sapiens]
          Length = 505

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 35/95 (36%), Positives = 41/95 (43%), Gaps = 14/95 (14%)

Query: 205 PGQVHQIPTHGIQPQP--QPPPQHPSQPSAQSAPAPAQPAP----QPPPA-----KVSKP 253
           P     +P +G+ P P   PP + PS P    AP P QP P    QPP A      V+ P
Sbjct: 94  PSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYP 153

Query: 254 SQLQAHTPASQQTPPLPPYAS-PRSPPVQPHTPVT 287
            Q     P  QQ  P+P Y   P S  V P  P T
Sbjct: 154 GQPPVPLPGQQQ--PVPSYPGYPGSGTVTPAVPPT 186



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 29/86 (33%), Positives = 30/86 (34%), Gaps = 10/86 (11%)

Query: 220 PQPPPQHPSQPSAQSAPAP----AQPAPQPPPAKVSKPSQLQAHTPASQQTPP--LPPYA 273
           P PP      PSAQ    P      P   PP    S P    A  P     PP   PP A
Sbjct: 84  PVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGA 143

Query: 274 SPRSPPV----QPHTPVTISLGTAPS 295
            P  PPV    QP  P+       PS
Sbjct: 144 YPGQPPVTYPGQPPVPLPGQQQPVPS 169


>gi|22165431 annexin A11 [Homo sapiens]
          Length = 505

 Score = 48.5 bits (114), Expect = 4e-05
 Identities = 35/95 (36%), Positives = 41/95 (43%), Gaps = 14/95 (14%)

Query: 205 PGQVHQIPTHGIQPQP--QPPPQHPSQPSAQSAPAPAQPAP----QPPPA-----KVSKP 253
           P     +P +G+ P P   PP + PS P    AP P QP P    QPP A      V+ P
Sbjct: 94  PSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGAYPGQPPVTYP 153

Query: 254 SQLQAHTPASQQTPPLPPYAS-PRSPPVQPHTPVT 287
            Q     P  QQ  P+P Y   P S  V P  P T
Sbjct: 154 GQPPVPLPGQQQ--PVPSYPGYPGSGTVTPAVPPT 186



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 29/86 (33%), Positives = 30/86 (34%), Gaps = 10/86 (11%)

Query: 220 PQPPPQHPSQPSAQSAPAP----AQPAPQPPPAKVSKPSQLQAHTPASQQTPP--LPPYA 273
           P PP      PSAQ    P      P   PP    S P    A  P     PP   PP A
Sbjct: 84  PVPPGGFGQPPSAQQPVPPYGMYPPPGGNPPSRMPSYPPYPGAPVPGQPMPPPGQQPPGA 143

Query: 274 SPRSPPV----QPHTPVTISLGTAPS 295
            P  PPV    QP  P+       PS
Sbjct: 144 YPGQPPVTYPGQPPVPLPGQQQPVPS 169


>gi|239746149 PREDICTED: hypothetical protein LOC80164 [Homo
           sapiens]
          Length = 816

 Score = 48.1 bits (113), Expect = 5e-05
 Identities = 68/283 (24%), Positives = 97/283 (34%), Gaps = 57/283 (20%)

Query: 21  PGSTEAFPHQHRVLAPAPPVYEAVSETMQSATGIQYSVTPSYQVSAMPQSSGSH-GPAIA 79
           P  + +   +H    P+P    A      +  G+Q   + S   SA P SS +  GP+  
Sbjct: 196 PRKSVSSASEHSTTEPSP----AARRRPSAGGGLQRPASRSLSSSATPLSSPARSGPSAR 251

Query: 80  AVHSSHHHPTAVQPHGGQVVQSHAHPAPPVAPVQGQQQFQRLKVEDALSYLDQVKLQFGS 139
               +  HP+  +P G Q ++      P V P +                          
Sbjct: 252 GTPRAPAHPSQPKPKGLQALRP-----PQVTPPR-------------------------- 280

Query: 140 QPQVYNDFLDIMKEFKSQSIDTPGVISRVSQLFKGHPDLIMGFNTF-LPPGYKIEVQTND 198
                 D    +    S  + TP   +  S      P       T   PP       T  
Sbjct: 281 -----KDAAPALGPLSSSPLATPSPSAPPS------PSAPPSLQTLPSPPATPPSQATTS 329

Query: 199 MVNVTTPGQVHQIPTHGIQPQPQPPPQHP---SQPSAQSAPAPAQPAPQPPPAKVS--KP 253
           + + T       +P+  + P   PPPQ P   + P  Q+ P+P    P  P A  S   P
Sbjct: 330 LGSPTLQATHSFLPSPPLSPLATPPPQAPPALALPPLQAPPSPPASPPLSPLATPSPQAP 389

Query: 254 SQLQAH-TPASQQTPPLPPYASPRSPPVQPHTPVTISLGTAPS 295
           + L  H   A    PP PP  +P SPP  P  PV+ S  T PS
Sbjct: 390 NALAVHLLQAPFSPPPSPPVQAPFSPPASP--PVSPS-ATPPS 429



 Score = 47.0 bits (110), Expect = 1e-04
 Identities = 31/90 (34%), Positives = 39/90 (43%), Gaps = 6/90 (6%)

Query: 212 PTHGIQPQPQPPPQHPSQPSA----QSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTP 267
           P+  +Q    PP   P  PSA    Q+ P+ A P  Q PP+  + P    + TP  Q  P
Sbjct: 405 PSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPP 464

Query: 268 PL--PPYASPRSPPVQPHTPVTISLGTAPS 295
           PL  PP    + PP  P    T  L   PS
Sbjct: 465 PLAAPPLQLAKPPPQAPPALATPPLQALPS 494



 Score = 45.4 bits (106), Expect = 3e-04
 Identities = 32/85 (37%), Positives = 40/85 (47%), Gaps = 12/85 (14%)

Query: 218 PQPQPPPQHPSQPSAQSAPAP-AQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPR 276
           P P PP Q P  P A    +P A P  Q PP+  + P Q+    PAS   PP+ P A   
Sbjct: 403 PPPSPPVQAPFSPPASPPVSPSATPPSQAPPSLAAPPLQVPPSPPAS---PPMSPSA--- 456

Query: 277 SPPVQPHTPVTISLGTAPSLQNNQP 301
           +PP Q   P+      AP LQ  +P
Sbjct: 457 TPPPQAPPPL-----AAPPLQLAKP 476



 Score = 42.7 bits (99), Expect = 0.002
 Identities = 29/85 (34%), Positives = 37/85 (43%), Gaps = 4/85 (4%)

Query: 218 PQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPLPPYASPRS 277
           P P  PP   + PS Q+ P+P  PA  P  A  S  S     T +   +PPL P A+P  
Sbjct: 298 PSPSAPPSPSAPPSLQTLPSP--PATPPSQATTSLGSPTLQATHSFLPSPPLSPLATP-- 353

Query: 278 PPVQPHTPVTISLGTAPSLQNNQPV 302
           PP  P       L   PS   + P+
Sbjct: 354 PPQAPPALALPPLQAPPSPPASPPL 378



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 30/94 (31%), Positives = 39/94 (41%), Gaps = 12/94 (12%)

Query: 210 QIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQP---PPAKVSKPSQLQAHTPASQQT 266
           Q P     P  Q PP  P+ P    +  P   AP P   PP +++KP       P +  T
Sbjct: 430 QAPPSLAAPPLQVPPSPPASPPMSPSATPPPQAPPPLAAPPLQLAKP---PPQAPPALAT 486

Query: 267 PPL-----PPYASPRSPPVQPHTPVTIS-LGTAP 294
           PPL     PP + P   P  P   + +S L T P
Sbjct: 487 PPLQALPSPPASFPGQAPFSPSASLPMSPLATPP 520



 Score = 42.0 bits (97), Expect = 0.004
 Identities = 32/84 (38%), Positives = 37/84 (44%), Gaps = 4/84 (4%)

Query: 216 IQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPAS--QQTPPLPPYA 273
           + P   PPPQ P  P A      A+P PQ PPA  + P Q     PAS   Q P  P  +
Sbjct: 452 MSPSATPPPQAP-PPLAAPPLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSAS 510

Query: 274 SPRSPPVQPHTPVTISLGTAPSLQ 297
            P SP   P  P    +  AP LQ
Sbjct: 511 LPMSPLATP-PPQAPPVLAAPLLQ 533



 Score = 40.4 bits (93), Expect = 0.011
 Identities = 29/82 (35%), Positives = 40/82 (48%), Gaps = 10/82 (12%)

Query: 224 PQHPSQPSAQSAPAPAQPAPQPPPAKVSKP-------SQLQAHTPASQQTPPLPP-YASP 275
           P HPSQP  +   A  +P    PP K + P       S L   +P++  +P  PP   + 
Sbjct: 257 PAHPSQPKPKGLQA-LRPPQVTPPRKDAAPALGPLSSSPLATPSPSAPPSPSAPPSLQTL 315

Query: 276 RSPPVQPHTPVTISLGTAPSLQ 297
            SPP  P +  T SLG +P+LQ
Sbjct: 316 PSPPATPPSQATTSLG-SPTLQ 336



 Score = 36.2 bits (82), Expect = 0.21
 Identities = 30/105 (28%), Positives = 38/105 (36%), Gaps = 22/105 (20%)

Query: 212 PTHGIQPQPQPPP-------------------QHPSQPSAQSAPAP-AQPAPQPPPAKVS 251
           P    +P PQ PP                   Q P  PSA    +P A P PQ PP   +
Sbjct: 470 PLQLAKPPPQAPPALATPPLQALPSPPASFPGQAPFSPSASLPMSPLATPPPQAPPVLAA 529

Query: 252 KPSQLQAHTPASQ--QTPPLPPYASPRSPPVQPHTPVTISLGTAP 294
              Q+    PAS   Q P  PP   P +    P   + ++ G  P
Sbjct: 530 PLLQVPPSPPASPTLQAPRRPPTPGPDTSVSGPRLTLALAPGPPP 574



 Score = 35.0 bits (79), Expect = 0.46
 Identities = 25/68 (36%), Positives = 28/68 (41%), Gaps = 7/68 (10%)

Query: 210 QIPTHGIQPQPQPPPQHPSQPSAQSAPAPAQPAPQPPPAKVSKPSQLQAHTPASQQTPPL 269
           Q P     P  Q PP  P+ P+ Q   AP +P    P   VS P    A  P     PP 
Sbjct: 522 QAPPVLAAPLLQVPPSPPASPTLQ---APRRPPTPGPDTSVSGPRLTLALAPG----PPP 574

Query: 270 PPYASPRS 277
           PP  SP S
Sbjct: 575 PPSRSPSS 582


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.315    0.131    0.382 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 52,188,834
Number of Sequences: 37866
Number of extensions: 2751239
Number of successful extensions: 43021
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 456
Number of HSP's successfully gapped in prelim test: 1123
Number of HSP's that attempted gapping in prelim test: 21891
Number of HSP's gapped (non-prelim): 12517
length of query: 1273
length of database: 18,247,518
effective HSP length: 114
effective length of query: 1159
effective length of database: 13,930,794
effective search space: 16145790246
effective search space used: 16145790246
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.6 bits)
S2: 68 (30.8 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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