BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|23110960 cathepsin L2 preproprotein [Homo sapiens] (334 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|23110960 cathepsin L2 preproprotein [Homo sapiens] 704 0.0 gi|22202619 cathepsin L1 preproprotein [Homo sapiens] 552 e-157 gi|4503155 cathepsin L1 preproprotein [Homo sapiens] 552 e-157 gi|4503151 cathepsin K preproprotein [Homo sapiens] 333 1e-91 gi|23110962 cathepsin S preproprotein [Homo sapiens] 329 2e-90 gi|23110957 cathepsin H isoform b precursor [Homo sapiens] 229 3e-60 gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens] 229 3e-60 gi|6042196 cathepsin F [Homo sapiens] 179 3e-45 gi|4557501 cathepsin O preproprotein [Homo sapiens] 141 9e-34 gi|23110964 cathepsin W preproprotein [Homo sapiens] 129 4e-30 gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens] 124 1e-28 gi|239744067 PREDICTED: similar to Putative cathepsin L-like pro... 117 1e-26 gi|22538437 cathepsin B preproprotein [Homo sapiens] 98 1e-20 gi|22538435 cathepsin B preproprotein [Homo sapiens] 98 1e-20 gi|22538433 cathepsin B preproprotein [Homo sapiens] 98 1e-20 gi|22538431 cathepsin B preproprotein [Homo sapiens] 98 1e-20 gi|4503139 cathepsin B preproprotein [Homo sapiens] 98 1e-20 gi|22538442 cathepsin Z preproprotein [Homo sapiens] 94 2e-19 gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens] 90 2e-18 gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo sa... 82 5e-16 gi|169189860 PREDICTED: similar to Cathepsin L1 [Homo sapiens] 74 1e-13 gi|46049092 nebulin-related anchoring protein isoform C [Homo sa... 30 3.0 gi|46049105 nebulin-related anchoring protein isoform S [Homo sa... 30 3.0 gi|149944640 zinc finger and BTB domain containing 34 [Homo sapi... 30 3.0 gi|51093381 leptin receptor isoform 3 [Homo sapiens] 29 6.7 gi|31442420 shroom family member 1 [Homo sapiens] 29 6.7 gi|109637798 RAD52 homolog [Homo sapiens] 28 8.8 gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens] 28 8.8 >gi|23110960 cathepsin L2 preproprotein [Homo sapiens] Length = 334 Score = 704 bits (1818), Expect = 0.0 Identities = 334/334 (100%), Positives = 334/334 (100%) Query: 1 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE 60 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE Sbjct: 1 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE 60 Query: 61 LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW 120 LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW Sbjct: 61 LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW 120 Query: 121 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 180 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG Sbjct: 121 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 180 Query: 181 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV 240 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV Sbjct: 181 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV 240 Query: 241 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK 300 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK Sbjct: 241 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK 300 Query: 301 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV Sbjct: 301 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334 >gi|22202619 cathepsin L1 preproprotein [Homo sapiens] Length = 333 Score = 552 bits (1423), Expect = e-157 Identities = 259/334 (77%), Positives = 291/334 (87%), Gaps = 1/334 (0%) Query: 1 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE 60 MN +L+LAAFCLGIASA FD +L+ +W +WKA H RLYG NEEGWRRAVWEKNMKMIE Sbjct: 1 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 60 Query: 61 LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW 120 LHN EY +GKH FTMAMNAFGDMT+EEFRQ+M F+N+K RKGKVF+EPLF + P+SVDW Sbjct: 61 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 120 Query: 121 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 180 R+KGYVTPVKNQ QCGSCWAFSATGALEGQMFRKTG+L+SLSEQNLVDCS PQGN+GCNG Sbjct: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180 Query: 181 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV 240 G M AFQYV++NGGLDSEESYPY A +E CKY P+ SVANDTGF V P +EKALMKAV Sbjct: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGF-VDIPKQEKALMKAV 239 Query: 241 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK 300 ATVGPISVA+DAGH SF FYK GIYFEPDCSS+++DHGVLVVGYGFE S+N+KYWLVK Sbjct: 240 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK 299 Query: 301 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334 NSWG EWG GYVK+AKD+ NHCGIA+AASYP V Sbjct: 300 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 >gi|4503155 cathepsin L1 preproprotein [Homo sapiens] Length = 333 Score = 552 bits (1423), Expect = e-157 Identities = 259/334 (77%), Positives = 291/334 (87%), Gaps = 1/334 (0%) Query: 1 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAVWEKNMKMIE 60 MN +L+LAAFCLGIASA FD +L+ +W +WKA H RLYG NEEGWRRAVWEKNMKMIE Sbjct: 1 MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE 60 Query: 61 LHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLPKSVDW 120 LHN EY +GKH FTMAMNAFGDMT+EEFRQ+M F+N+K RKGKVF+EPLF + P+SVDW Sbjct: 61 LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW 120 Query: 121 RKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNG 180 R+KGYVTPVKNQ QCGSCWAFSATGALEGQMFRKTG+L+SLSEQNLVDCS PQGN+GCNG Sbjct: 121 REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG 180 Query: 181 GFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAV 240 G M AFQYV++NGGLDSEESYPY A +E CKY P+ SVANDTGF V P +EKALMKAV Sbjct: 181 GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGF-VDIPKQEKALMKAV 239 Query: 241 ATVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVK 300 ATVGPISVA+DAGH SF FYK GIYFEPDCSS+++DHGVLVVGYGFE S+N+KYWLVK Sbjct: 240 ATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVK 299 Query: 301 NSWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334 NSWG EWG GYVK+AKD+ NHCGIA+AASYP V Sbjct: 300 NSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV 333 >gi|4503151 cathepsin K preproprotein [Homo sapiens] Length = 329 Score = 333 bits (854), Expect = 1e-91 Identities = 164/319 (51%), Positives = 213/319 (66%), Gaps = 14/319 (4%) Query: 22 DQNLDTKWYQWKATHRRLYGAN-EEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAF 80 ++ LDT W WK THR+ Y +E RR +WEKN+K I +HN E S G H + +AMN Sbjct: 19 EEILDTHWELWKKTHRKQYNNKVDEISRRLIWEKNLKYISIHNLEASLGVHTYELAMNHL 78 Query: 81 GDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLD-----LPKSVDWRKKGYVTPVKNQKQC 135 GDMT+EE Q M + + L++ P SVD+RKKGYVTPVKNQ QC Sbjct: 79 GDMTSEEVVQKMTGLKVPLSHSRS--NDTLYIPEWEGRAPDSVDYRKKGYVTPVKNQGQC 136 Query: 136 GSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGG 195 GSCWAFS+ GALEGQ+ +KTGKL++LS QNLVDC N GC GG+M AFQYV++N G Sbjct: 137 GSCWAFSSVGALEGQLKKKTGKLLNLSPQNLVDCVSE--NDGCGGGYMTNAFQYVQKNRG 194 Query: 196 LDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHS 255 +DSE++YPYV +E C Y P A G+ + G EKAL +AVA VGP+SVA+DA + Sbjct: 195 IDSEDAYPYVGQEESCMYNPTGKAAKCRGYREIPEGNEKALKRAVARVGPVSVAIDASLT 254 Query: 256 SFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKI 315 SFQFY G+Y++ C+S NL+H VL VGYG + N K+W++KNSWG WG+ GY+ + Sbjct: 255 SFQFYSKGVYYDESCNSDNLNHAVLAVGYGIQKGN----KHWIIKNSWGENWGNKGYILM 310 Query: 316 AKDKNNHCGIATAASYPNV 334 A++KNN CGIA AS+P + Sbjct: 311 ARNKNNACGIANLASFPKM 329 >gi|23110962 cathepsin S preproprotein [Homo sapiens] Length = 331 Score = 329 bits (843), Expect = 2e-90 Identities = 166/333 (49%), Positives = 222/333 (66%), Gaps = 10/333 (3%) Query: 7 LAAFCLGIASAVPKF--DQNLDTKWYQWKATHRRLYGA-NEEGWRRAVWEKNMKMIELHN 63 L L +SAV + D LD W+ WK T+ + Y NEE RR +WEKN+K + LHN Sbjct: 4 LVCVLLVCSSAVAQLHKDPTLDHHWHLWKKTYGKQYKEKNEEAVRRLIWEKNLKFVMLHN 63 Query: 64 GEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFR-NQKFRKGKVFREPLFLDLPKSVDWRK 122 E+S G H + + MN GDMT+EE +M R ++++ ++ LP SVDWR+ Sbjct: 64 LEHSMGMHSYDLGMNHLGDMTSEEVMSLMSSLRVPSQWQRNITYKSNPNRILPDSVDWRE 123 Query: 123 KGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQ-GNQGCNGG 181 KG VT VK Q CG+CWAFSA GALE Q+ KTGKLVSLS QNLVDCS + GN+GCNGG Sbjct: 124 KGCVTEVKYQGSCGACWAFSAVGALEAQLKLKTGKLVSLSAQNLVDCSTEKYGNKGCNGG 183 Query: 182 FMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVAPGKEKALMKAVA 241 FM AFQY+ +N G+DS+ SYPY A+D+ C+Y + A + +T + G+E L +AVA Sbjct: 184 FMTTAFQYIIDNKGIDSDASYPYKAMDQKCQYDSKYRAATCSKYTELPYGREDVLKEAVA 243 Query: 242 TVGPISVAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKN 301 GP+SV +DA H SF Y+SG+Y+EP C ++N++HGVLVVGYG + N +YWLVKN Sbjct: 244 NKGPVSVGVDARHPSFFLYRSGVYYEPSC-TQNVNHGVLVVGYG----DLNGKEYWLVKN 298 Query: 302 SWGPEWGSNGYVKIAKDKNNHCGIATAASYPNV 334 SWG +G GY+++A++K NHCGIA+ SYP + Sbjct: 299 SWGHNFGEEGYIRMARNKGNHCGIASFPSYPEI 331 >gi|23110957 cathepsin H isoform b precursor [Homo sapiens] Length = 323 Score = 229 bits (583), Expect = 3e-60 Identities = 124/304 (40%), Positives = 166/304 (54%), Gaps = 13/304 (4%) Query: 32 WKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQM 91 W + HR+ Y E R + N + I HN G H F MA+N F DM+ E + Sbjct: 26 WMSKHRKTYSTEEYHHRLQTFASNWRKINAHNN----GNHTFKMALNQFSDMSFAEIKHK 81 Query: 92 MGCFRNQKFRKGKVFREPLFLDLPKSVDWRKKG-YVTPVKNQKQCGSCWAFSATGALEGQ 150 Q K P SVDWRKKG +V+PVKNQ CGSCW FS TGALE Sbjct: 82 YLWSEPQNCSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESA 141 Query: 151 MFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEI 210 + TGK++SL+EQ LVDC++ N GC GG ++AF+Y+ N G+ E++YPY D Sbjct: 142 IAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGY 201 Query: 211 CKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDC 270 CK++P ++ + E+A+++AVA P+S A + F Y++GIY C Sbjct: 202 CKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEV-TQDFMMYRTGIYSSTSC 260 Query: 271 --SSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATA 328 + ++H VL VGYG N YW+VKNSWGP+WG NGY I + K N CG+A Sbjct: 261 HKTPDKVNHAVLAVGYG----EKNGIPYWIVKNSWGPQWGMNGYFLIERGK-NMCGLAAC 315 Query: 329 ASYP 332 ASYP Sbjct: 316 ASYP 319 >gi|23110955 cathepsin H isoform a preproprotein [Homo sapiens] Length = 335 Score = 229 bits (583), Expect = 3e-60 Identities = 124/304 (40%), Positives = 166/304 (54%), Gaps = 13/304 (4%) Query: 32 WKATHRRLYGANEEGWRRAVWEKNMKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQM 91 W + HR+ Y E R + N + I HN G H F MA+N F DM+ E + Sbjct: 38 WMSKHRKTYSTEEYHHRLQTFASNWRKINAHNN----GNHTFKMALNQFSDMSFAEIKHK 93 Query: 92 MGCFRNQKFRKGKVFREPLFLDLPKSVDWRKKG-YVTPVKNQKQCGSCWAFSATGALEGQ 150 Q K P SVDWRKKG +V+PVKNQ CGSCW FS TGALE Sbjct: 94 YLWSEPQNCSATKSNYLRGTGPYPPSVDWRKKGNFVSPVKNQGACGSCWTFSTTGALESA 153 Query: 151 MFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEI 210 + TGK++SL+EQ LVDC++ N GC GG ++AF+Y+ N G+ E++YPY D Sbjct: 154 IAIATGKMLSLAEQQLVDCAQDFNNHGCQGGLPSQAFEYILYNKGIMGEDTYPYQGKDGY 213 Query: 211 CKYRPENSVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEPDC 270 CK++P ++ + E+A+++AVA P+S A + F Y++GIY C Sbjct: 214 CKFQPGKAIGFVKDVANITIYDEEAMVEAVALYNPVSFAFEV-TQDFMMYRTGIYSSTSC 272 Query: 271 --SSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATA 328 + ++H VL VGYG N YW+VKNSWGP+WG NGY I + K N CG+A Sbjct: 273 HKTPDKVNHAVLAVGYG----EKNGIPYWIVKNSWGPQWGMNGYFLIERGK-NMCGLAAC 327 Query: 329 ASYP 332 ASYP Sbjct: 328 ASYP 331 >gi|6042196 cathepsin F [Homo sapiens] Length = 484 Score = 179 bits (454), Expect = 3e-45 Identities = 120/309 (38%), Positives = 164/309 (53%), Gaps = 35/309 (11%) Query: 35 THRRLYGANEEG-WRRAVWEKNM----KMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFR 89 T+ R Y + EE WR +V+ NM K+ L G G + F D+T EEFR Sbjct: 193 TYNRTYESKEEARWRLSVFVNNMVRAQKIQALDRGTAQYG-------VTKFSDLTEEEFR 245 Query: 90 QMMGCFRNQKFRK---GKVFREPLFLDL-PKSVDWRKKGYVTPVKNQKQCGSCWAFSATG 145 + + N RK K+ + DL P DWR KG VT VK+Q CGSCWAFS TG Sbjct: 246 TI---YLNTLLRKEPGNKMKQAKSVGDLAPPEWDWRSKGAVTKVKDQGMCGSCWAFSVTG 302 Query: 146 ALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYV 205 +EGQ F G L+SLSEQ L+DC + ++ C GG + A+ +K GGL++E+ Y Y Sbjct: 303 NVEGQWFLNQGTLLSLSEQELLDCDKM--DKACMGGLPSNAYSAIKNLGGLETEDDYSYQ 360 Query: 206 AVDEICKYRPENS--VANDTGFTVVAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSG 263 + C + E + ND +V E+ L +A GPISVA++A QFY+ G Sbjct: 361 GHMQSCNFSAEKAKVYIND---SVELSQNEQKLAAWLAKRGPISVAINA--FGMQFYRHG 415 Query: 264 IY--FEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNN 321 I P CS +DH VL+VGYG N ++ +W +KNSWG +WG GY + + + Sbjct: 416 ISRPLRPLCSPWLIDHAVLLVGYG----NRSDVPFWAIKNSWGTDWGEKGYYYLHRG-SG 470 Query: 322 HCGIATAAS 330 CG+ T AS Sbjct: 471 ACGVNTMAS 479 >gi|4557501 cathepsin O preproprotein [Homo sapiens] Length = 321 Score = 141 bits (355), Expect = 9e-34 Identities = 93/263 (35%), Positives = 134/263 (50%), Gaps = 23/263 (8%) Query: 77 MNAFGDMTNEEFRQMMGCFRNQKFRK--GKVFREPLFLDLPKSVDWRKKGYVTPVKNQKQ 134 +N F + EEF+ + + KF + +V + LP DWR K VT V+NQ+ Sbjct: 69 INQFSYLFPEEFKAIYLRSKPSKFPRYSAEVHMSIPNVSLPLRFDWRDKQVVTQVRNQQM 128 Query: 135 CGSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYV-KEN 193 CG CWAFS GA+E K L LS Q ++DCS N GCNGG A ++ K Sbjct: 129 CGGCWAFSVVGAVESAYAIKGKPLEDLSVQQVIDCS--YNNYGCNGGSTLNALNWLNKMQ 186 Query: 194 GGLDSEESYPYVAVDEICKYRPENSVANDTGFTVVA------PGKEKALMKAVATVGPIS 247 L + YP+ A + +C Y + +GF++ +E + KA+ T GP+ Sbjct: 187 VKLVKDSEYPFKAQNGLCHY----FSGSHSGFSIKGYSAYDFSDQEDEMAKALLTFGPLV 242 Query: 248 VAMDAGHSSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEW 307 V +DA S+Q Y GI + CSS +H VL+ G+ G ++ YW+V+NSWG W Sbjct: 243 VIVDA--VSWQDYLGGI-IQHHCSSGEANHAVLITGFDKTG----STPYWIVRNSWGSSW 295 Query: 308 GSNGYVKIAKDKNNHCGIATAAS 330 G +GY + K +N CGIA + S Sbjct: 296 GVDGYAHV-KMGSNVCGIADSVS 317 >gi|23110964 cathepsin W preproprotein [Homo sapiens] Length = 376 Score = 129 bits (324), Expect = 4e-30 Identities = 91/270 (33%), Positives = 132/270 (48%), Gaps = 30/270 (11%) Query: 80 FGDMTNEEFRQMMGCFRNQKF--RKGKVFR-EPLFLDLPKSVDWRK-KGYVTPVKNQKQC 135 F D+T EEF Q+ G R G+ R E +P S DWRK G ++P+K+QK C Sbjct: 91 FSDLTEEEFGQLYGYRRAAGGVPSMGREIRSEEPEESVPFSCDWRKVAGAISPIKDQKNC 150 Query: 136 GSCWAFSATGALEGQMFRKTGKLVSLSEQNLVDCSRPQGNQGCNGGFMARAFQYVKENGG 195 CWA +A G +E V +S Q L+DC R GC+GGF+ AF V N G Sbjct: 151 NCCWAMAAAGNIETLWRISFWDFVDVSVQELLDCGRC--GDGCHGGFVWDAFITVLNNSG 208 Query: 196 LDSEESYPYVAVDEICKYRPEN--SVANDTGFTVVAPGKEKALMKAVATVGPISVAMDAG 253 L SE+ YP+ + P+ VA F ++ E + + +AT GPI+V ++ Sbjct: 209 LASEKDYPFQGKVRAHRCHPKKYQKVAWIQDF-IMLQNNEHRIAQYLATYGPITVTINM- 266 Query: 254 HSSFQFYKSGIY--FEPDCSSKNLDHGVLVVGYGF---------EGANSNN-------SK 295 Q Y+ G+ C + +DH VL+VG+G E +S + + Sbjct: 267 -KPLQLYRKGVIKATPTTCDPQLVDHSVLLVGFGSVKSEEGIWAETVSSQSQPQPPHPTP 325 Query: 296 YWLVKNSWGPEWGSNGYVKIAKDKNNHCGI 325 YW++KNSWG +WG GY ++ + N CGI Sbjct: 326 YWILKNSWGAQWGEKGYFRLHRGSNT-CGI 354 >gi|189083844 cathepsin C isoform a preproprotein [Homo sapiens] Length = 463 Score = 124 bits (311), Expect = 1e-28 Identities = 83/232 (35%), Positives = 119/232 (51%), Gaps = 20/232 (8%) Query: 112 LDLPKSVDWRKK---GYVTPVKNQKQCGSCWAFSATGALEGQM--FRKTGKLVSLSEQNL 166 L LP S DWR +V+PV+NQ CGSC++F++ G LE ++ + LS Q + Sbjct: 229 LHLPTSWDWRNVHGINFVSPVRNQASCGSCYSFASMGMLEARIRILTNNSQTPILSPQEV 288 Query: 167 VDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEICKYRPENSVANDTGFT 226 V CS Q QGC GGF ++ GL E +PY D CK + + + + Sbjct: 289 VSCS--QYAQGCEGGFPYLIAGKYAQDFGLVEEACFPYTGTDSPCKMKEDCFRYYSSEYH 346 Query: 227 VVAP---GKEKALMKA-VATVGPISVAMDAGHSSFQFYKSGIYF-----EPDCSSKNLDH 277 V G +ALMK + GP++VA + + F YK GIY +P + +H Sbjct: 347 YVGGFYGGCNEALMKLELVHHGPMAVAFEV-YDDFLHYKKGIYHHTGLRDPFNPFELTNH 405 Query: 278 GVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAKDKNNHCGIATAA 329 VL+VGYG + A+ + YW+VKNSWG WG NGY +I + + C I + A Sbjct: 406 AVLLVGYGTDSASGMD--YWIVKNSWGTGWGENGYFRIRRG-TDECAIESIA 454 >gi|239744067 PREDICTED: similar to Putative cathepsin L-like protein 6 [Homo sapiens] Length = 81 Score = 117 bits (293), Expect = 1e-26 Identities = 55/77 (71%), Positives = 62/77 (80%) Query: 56 MKMIELHNGEYSQGKHGFTMAMNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLDLP 115 MKM E HN EYSQGKH FTMAMN FGDMT EEFRQ+M F+ QK R GK F+E L L++P Sbjct: 1 MKMTEQHNQEYSQGKHSFTMAMNTFGDMTTEEFRQVMNGFQYQKHRNGKQFQERLLLEIP 60 Query: 116 KSVDWRKKGYVTPVKNQ 132 SVDWR+KGYVTPVK+Q Sbjct: 61 TSVDWREKGYVTPVKDQ 77 >gi|22538437 cathepsin B preproprotein [Homo sapiens] Length = 339 Score = 97.8 bits (242), Expect = 1e-20 Identities = 74/251 (29%), Positives = 110/251 (43%), Gaps = 44/251 (17%) Query: 112 LDLPKSVD----WRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSL--SEQN 165 L LP S D W + + +++Q CGSCWAF A A+ ++ T VS+ S ++ Sbjct: 78 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137 Query: 166 LVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSE--ESY----PYVA------------- 206 L+ C GCNGG+ A A+ + G + ES+ PY Sbjct: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 Query: 207 ---------VDEICK--YRPENSVANDTGFTVVA-PGKEKALMKAVATVGPISVAMDAGH 254 +IC+ Y P G+ + EK +M + GP+ A + Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 256 Query: 255 SSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVK 314 S F YKSG+Y H + ++G+G E N + YWLV NSW +WG NG+ K Sbjct: 257 SDFLLYKSGVYQHVTGEMMG-GHAIRILGWGVE----NGTPYWLVANSWNTDWGDNGFFK 311 Query: 315 IAKDKNNHCGI 325 I + + +HCGI Sbjct: 312 ILRGQ-DHCGI 321 >gi|22538435 cathepsin B preproprotein [Homo sapiens] Length = 339 Score = 97.8 bits (242), Expect = 1e-20 Identities = 74/251 (29%), Positives = 110/251 (43%), Gaps = 44/251 (17%) Query: 112 LDLPKSVD----WRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSL--SEQN 165 L LP S D W + + +++Q CGSCWAF A A+ ++ T VS+ S ++ Sbjct: 78 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137 Query: 166 LVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSE--ESY----PYVA------------- 206 L+ C GCNGG+ A A+ + G + ES+ PY Sbjct: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 Query: 207 ---------VDEICK--YRPENSVANDTGFTVVA-PGKEKALMKAVATVGPISVAMDAGH 254 +IC+ Y P G+ + EK +M + GP+ A + Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 256 Query: 255 SSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVK 314 S F YKSG+Y H + ++G+G E N + YWLV NSW +WG NG+ K Sbjct: 257 SDFLLYKSGVYQHVTGEMMG-GHAIRILGWGVE----NGTPYWLVANSWNTDWGDNGFFK 311 Query: 315 IAKDKNNHCGI 325 I + + +HCGI Sbjct: 312 ILRGQ-DHCGI 321 >gi|22538433 cathepsin B preproprotein [Homo sapiens] Length = 339 Score = 97.8 bits (242), Expect = 1e-20 Identities = 74/251 (29%), Positives = 110/251 (43%), Gaps = 44/251 (17%) Query: 112 LDLPKSVD----WRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSL--SEQN 165 L LP S D W + + +++Q CGSCWAF A A+ ++ T VS+ S ++ Sbjct: 78 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137 Query: 166 LVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSE--ESY----PYVA------------- 206 L+ C GCNGG+ A A+ + G + ES+ PY Sbjct: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 Query: 207 ---------VDEICK--YRPENSVANDTGFTVVA-PGKEKALMKAVATVGPISVAMDAGH 254 +IC+ Y P G+ + EK +M + GP+ A + Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 256 Query: 255 SSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVK 314 S F YKSG+Y H + ++G+G E N + YWLV NSW +WG NG+ K Sbjct: 257 SDFLLYKSGVYQHVTGEMMG-GHAIRILGWGVE----NGTPYWLVANSWNTDWGDNGFFK 311 Query: 315 IAKDKNNHCGI 325 I + + +HCGI Sbjct: 312 ILRGQ-DHCGI 321 >gi|22538431 cathepsin B preproprotein [Homo sapiens] Length = 339 Score = 97.8 bits (242), Expect = 1e-20 Identities = 74/251 (29%), Positives = 110/251 (43%), Gaps = 44/251 (17%) Query: 112 LDLPKSVD----WRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSL--SEQN 165 L LP S D W + + +++Q CGSCWAF A A+ ++ T VS+ S ++ Sbjct: 78 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137 Query: 166 LVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSE--ESY----PYVA------------- 206 L+ C GCNGG+ A A+ + G + ES+ PY Sbjct: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 Query: 207 ---------VDEICK--YRPENSVANDTGFTVVA-PGKEKALMKAVATVGPISVAMDAGH 254 +IC+ Y P G+ + EK +M + GP+ A + Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 256 Query: 255 SSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVK 314 S F YKSG+Y H + ++G+G E N + YWLV NSW +WG NG+ K Sbjct: 257 SDFLLYKSGVYQHVTGEMMG-GHAIRILGWGVE----NGTPYWLVANSWNTDWGDNGFFK 311 Query: 315 IAKDKNNHCGI 325 I + + +HCGI Sbjct: 312 ILRGQ-DHCGI 321 >gi|4503139 cathepsin B preproprotein [Homo sapiens] Length = 339 Score = 97.8 bits (242), Expect = 1e-20 Identities = 74/251 (29%), Positives = 110/251 (43%), Gaps = 44/251 (17%) Query: 112 LDLPKSVD----WRKKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKTGKLVSL--SEQN 165 L LP S D W + + +++Q CGSCWAF A A+ ++ T VS+ S ++ Sbjct: 78 LKLPASFDAREQWPQCPTIKEIRDQGSCGSCWAFGAVEAISDRICIHTNAHVSVEVSAED 137 Query: 166 LVDCSRPQGNQGCNGGFMARAFQYVKENGGLDSE--ESY----PYVA------------- 206 L+ C GCNGG+ A A+ + G + ES+ PY Sbjct: 138 LLTCCGSMCGDGCNGGYPAEAWNFWTRKGLVSGGLYESHVGCRPYSIPPCEHHVNGSRPP 197 Query: 207 ---------VDEICK--YRPENSVANDTGFTVVA-PGKEKALMKAVATVGPISVAMDAGH 254 +IC+ Y P G+ + EK +M + GP+ A + Sbjct: 198 CTGEGDTPKCSKICEPGYSPTYKQDKHYGYNSYSVSNSEKDIMAEIYKNGPVEGAFSV-Y 256 Query: 255 SSFQFYKSGIYFEPDCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVK 314 S F YKSG+Y H + ++G+G E N + YWLV NSW +WG NG+ K Sbjct: 257 SDFLLYKSGVYQHVTGEMMG-GHAIRILGWGVE----NGTPYWLVANSWNTDWGDNGFFK 311 Query: 315 IAKDKNNHCGI 325 I + + +HCGI Sbjct: 312 ILRGQ-DHCGI 321 >gi|22538442 cathepsin Z preproprotein [Homo sapiens] Length = 303 Score = 94.0 bits (232), Expect = 2e-19 Identities = 74/227 (32%), Positives = 114/227 (50%), Gaps = 36/227 (15%) Query: 113 DLPKSVDWRKK---GYVTPVKNQ---KQCGSCWAFSATGALEGQM-FRKTGKLVS--LSE 163 DLPKS DWR Y + +NQ + CGSCWA ++T A+ ++ ++ G S LS Sbjct: 61 DLPKSWDWRNVDGVNYASITRNQHIPQYCGSCWAHASTSAMADRINIKRKGAWPSTLLSV 120 Query: 164 QNLVDCSRPQGNQG-CNGGFMARAFQYVKENGGLDSEESYPYVAVDEIC----------K 212 QN++DC GN G C GG + Y ++G + E Y A D+ C + Sbjct: 121 QNVIDC----GNAGSCEGGNDLSVWDYAHQHG-IPDETCNNYQAKDQECDKFNQCGTCNE 175 Query: 213 YRPENSVANDTGFTV----VAPGKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFEP 268 ++ +++ N T + V G+EK + + A GPIS + A Y GIY E Sbjct: 176 FKECHAIRNYTLWRVGDYGSLSGREKMMAEIYAN-GPISCGIMATERLAN-YTGGIYAEY 233 Query: 269 DCSSKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKI 315 + ++H V V G+G S+ ++YW+V+NSWG WG G+++I Sbjct: 234 Q-DTTYINHVVSVAGWGI----SDGTEYWIVRNSWGEPWGERGWLRI 275 >gi|224586907 tubulointerstitial nephritis antigen [Homo sapiens] Length = 476 Score = 90.1 bits (222), Expect = 2e-18 Identities = 83/305 (27%), Positives = 127/305 (41%), Gaps = 61/305 (20%) Query: 65 EYSQGKHGFTMA-MNAFGDMTNEEFRQMMGCFRNQKFRKGKVFREPLFLD-------LPK 116 + ++G +G+T + F MT E+ KFR G + P+ L LP Sbjct: 163 QVNKGDYGWTAQNYSQFWGMTLED---------GFKFRLGTLPPSPMLLSMNEMTASLPA 213 Query: 117 SVD--------WRKKGYVTPVKNQKQCGSCWAFS-ATGALEGQMFRKTGKLVS-LSEQNL 166 + D ++ G+ +QK C + WAFS A+ A + + G+ + LS QNL Sbjct: 214 TTDLPEFFVASYKWPGWTHGPLDQKNCAASWAFSTASVAADRIAIQSKGRYTANLSPQNL 273 Query: 167 VDCSRPQGNQGCNGGFMARAFQYVKENGGLDSEESYPYV----AVDEIC----------- 211 + C + GCN G + RA+ Y+++ G L S YP A + C Sbjct: 274 ISCCA-KNRHGCNSGSIDRAWWYLRKRG-LVSHACYPLFKDQNATNNGCAMASRSDGRGK 331 Query: 212 ----KYRPENSVANDTGFTVVAP----GKEKALMKAVATVGPISVAMDAGHSSFQFYKSG 263 K P N ++ + P E +MK + GP+ M F YK+G Sbjct: 332 RHATKPCPNNVEKSNRIYQCSPPYRVSSNETEIMKEIMQNGPVQAIMQVREDFFH-YKTG 390 Query: 264 IYFEPDCSSKNLD-------HGVLVVGYG-FEGANSNNSKYWLVKNSWGPEWGSNGYVKI 315 IY ++K + H V + G+G GA K+W+ NSWG WG NGY +I Sbjct: 391 IYRHVTSTNKESEKYRKLQTHAVKLTGWGTLRGAQGQKEKFWIAANSWGKSWGENGYFRI 450 Query: 316 AKDKN 320 + N Sbjct: 451 LRGVN 455 >gi|11545918 tubulointerstitial nephritis antigen-like 1 [Homo sapiens] Length = 467 Score = 82.4 bits (202), Expect = 5e-16 Identities = 64/226 (28%), Positives = 92/226 (40%), Gaps = 39/226 (17%) Query: 131 NQKQCGSCWAFSATGALEGQM-FRKTGKLVS-LSEQNLVDCSRPQGNQGCNGGFMARAFQ 188 +Q C WAFS ++ G + LS QNL+ C Q QGC GG + A+ Sbjct: 222 DQGNCAGSWAFSTAAVASDRVSIHSLGHMTPVLSPQNLLSCDTHQ-QQGCRGGRLDGAWW 280 Query: 189 YVKENGGLDSEESYPYVAV--DEICKYRP-------------------ENSVANDTGFTV 227 +++ G + S+ YP+ DE P NS N+ Sbjct: 281 FLRRRGVV-SDHCYPFSGRERDEAGPAPPCMMHSRAMGRGKRQATAHCPNSYVNNNDIYQ 339 Query: 228 VAP-----GKEKALMKAVATVGPISVAMDAGHSSFQFYKSGIYFE-------PDCSSKNL 275 V P +K +MK + GP+ M+ H F YK GIY P+ ++ Sbjct: 340 VTPVYRLGSNDKEIMKELMENGPVQALMEV-HEDFFLYKGGIYSHTPVSLGRPERYRRHG 398 Query: 276 DHGVLVVGYGFEGANSNNS-KYWLVKNSWGPEWGSNGYVKIAKDKN 320 H V + G+G E + KYW NSWGP WG G+ +I + N Sbjct: 399 THSVKITGWGEETLPDGRTLKYWTAANSWGPAWGERGHFRIVRGVN 444 >gi|169189860 PREDICTED: similar to Cathepsin L1 [Homo sapiens] Length = 51 Score = 74.3 bits (181), Expect = 1e-13 Identities = 35/51 (68%), Positives = 40/51 (78%) Query: 1 MNLSLVLAAFCLGIASAVPKFDQNLDTKWYQWKATHRRLYGANEEGWRRAV 51 MN SL+LAAF LGIASA D +LD +W +WKA H+RLYG NEEGWRRAV Sbjct: 1 MNPSLLLAAFFLGIASAALTRDHSLDAQWTKWKAKHKRLYGMNEEGWRRAV 51 >gi|46049092 nebulin-related anchoring protein isoform C [Homo sapiens] Length = 1695 Score = 30.0 bits (66), Expect = 3.0 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 4/47 (8%) Query: 118 VDWRKKGYVTPVKNQKQCGSCW----AFSATGALEGQMFRKTGKLVS 160 V+W KK Y NQ + W + ATG+L + +K G+L+S Sbjct: 876 VEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELIS 922 >gi|46049105 nebulin-related anchoring protein isoform S [Homo sapiens] Length = 1730 Score = 30.0 bits (66), Expect = 3.0 Identities = 16/47 (34%), Positives = 24/47 (51%), Gaps = 4/47 (8%) Query: 118 VDWRKKGYVTPVKNQKQCGSCW----AFSATGALEGQMFRKTGKLVS 160 V+W KK Y NQ + W + ATG+L + +K G+L+S Sbjct: 911 VEWAKKAYGLQSDNQYRADVKWMKGMGWVATGSLNVEQAKKAGELIS 957 >gi|149944640 zinc finger and BTB domain containing 34 [Homo sapiens] Length = 500 Score = 30.0 bits (66), Expect = 3.0 Identities = 18/54 (33%), Positives = 24/54 (44%), Gaps = 1/54 (1%) Query: 62 HNGEYSQGKHGFTMAMNAFGDMTNEE-FRQMMGCFRNQKFRKGKVFREPLFLDL 114 H YSQ T AFG ++N R M+ CFR + R+ + L DL Sbjct: 281 HAYSYSQAASQPTNVSEAFGSLSNSSPSRSMLSCFRGGRARQKRALSVHLHSDL 334 >gi|51093381 leptin receptor isoform 3 [Homo sapiens] Length = 958 Score = 28.9 bits (63), Expect = 6.7 Identities = 21/55 (38%), Positives = 25/55 (45%), Gaps = 3/55 (5%) Query: 122 KKGYVTPVKNQKQCGSCWAFSATGALEGQMFRKT--GKLVSLSEQNLVDCSRPQG 174 KK + V N K C + LEG MF K+ L+S S Q C RPQG Sbjct: 868 KKLFWEDVPNPKNCSWAQGLNFQKMLEGSMFVKSHHHSLIS-STQGHKHCGRPQG 921 >gi|31442420 shroom family member 1 [Homo sapiens] Length = 847 Score = 28.9 bits (63), Expect = 6.7 Identities = 18/46 (39%), Positives = 23/46 (50%), Gaps = 3/46 (6%) Query: 272 SKNLDHGVLVVGYGFEGANSNNSKYWLVKNSWGPEWGSNGYVKIAK 317 S NLD G L +G F A+ + S V SWG GS G + I + Sbjct: 284 SMNLDSGSLKLGDAFRPASRSRSASGEVLGSWG---GSGGTIPIVQ 326 >gi|109637798 RAD52 homolog [Homo sapiens] Length = 418 Score = 28.5 bits (62), Expect = 8.8 Identities = 13/42 (30%), Positives = 24/42 (57%), Gaps = 4/42 (9%) Query: 36 HRRLYGANE----EGWRRAVWEKNMKMIELHNGEYSQGKHGF 73 HR + ANE GW ++ ++N+ ++L+NG++ G F Sbjct: 69 HRVINLANEMFGYNGWAHSITQQNVDFVDLNNGKFYVGVCAF 110 >gi|5454016 retinitis pigmentosa RP1 protein [Homo sapiens] Length = 2156 Score = 28.5 bits (62), Expect = 8.8 Identities = 19/73 (26%), Positives = 33/73 (45%), Gaps = 16/73 (21%) Query: 159 VSLSEQNLVDCSR-------PQGNQGCNGGFMARAFQYVKENGGLDSEESYPYVAVDEIC 211 V +E ++V+CS P N G F+ + +++ + GL D +C Sbjct: 937 VCRNETSVVNCSNNSFSGNDPHTNSGKISNFVMESNKHITKIAGLTG---------DNLC 987 Query: 212 KYRPENSVANDTG 224 K ++ +ANDTG Sbjct: 988 KEGDKSFIANDTG 1000 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.318 0.133 0.422 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 12,969,657 Number of Sequences: 37866 Number of extensions: 559154 Number of successful extensions: 1111 Number of sequences better than 10.0: 28 Number of HSP's better than 10.0 without gapping: 21 Number of HSP's successfully gapped in prelim test: 7 Number of HSP's that attempted gapping in prelim test: 1024 Number of HSP's gapped (non-prelim): 40 length of query: 334 length of database: 18,247,518 effective HSP length: 103 effective length of query: 231 effective length of database: 14,347,320 effective search space: 3314230920 effective search space used: 3314230920 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.