Guide to the Human Genome
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Search of human proteins with 227497758

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|227497758 beta-1,4-N-acetyl-galactosaminyl transferase 2
isoform c [Homo sapiens]
         (480 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|227498224 beta-1,4-N-acetyl-galactosaminyl transferase 2 isof...   972   0.0  
gi|227497758 beta-1,4-N-acetyl-galactosaminyl transferase 2 isof...   972   0.0  
gi|227497754 beta-1,4-N-acetyl-galactosaminyl transferase 2 isof...   972   0.0  
gi|4503893 beta-1,4-N-acetyl-galactosaminyl transferase 1 [Homo ...   368   e-102
gi|221316650 ephrin receptor EphA1 [Homo sapiens]                      31   2.8  
gi|46370057 ring finger protein 216 isoform b [Homo sapiens]           30   6.3  
gi|46358403 ring finger protein 216 isoform a [Homo sapiens]           30   6.3  
gi|222136639 methylenetetrahydrofolate dehydrogenase 1 [Homo sap...    29   8.3  
gi|82775371 coiled-coil domain containing 93 [Homo sapiens]            29   8.3  

>gi|227498224 beta-1,4-N-acetyl-galactosaminyl transferase 2 isoform
           b [Homo sapiens]
          Length = 506

 Score =  972 bits (2512), Expect = 0.0
 Identities = 480/480 (100%), Positives = 480/480 (100%)

Query: 1   MFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRNLFSYDGIWLFPKNQCKCEANKE 60
           MFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRNLFSYDGIWLFPKNQCKCEANKE
Sbjct: 27  MFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRNLFSYDGIWLFPKNQCKCEANKE 86

Query: 61  QGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPLLVQPNLPFGYPVHGVEVMP 120
           QGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPLLVQPNLPFGYPVHGVEVMP
Sbjct: 87  QGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPLLVQPNLPFGYPVHGVEVMP 146

Query: 121 LHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPDSVVQGRGQKQLIISTSDRKLLK 180
           LHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPDSVVQGRGQKQLIISTSDRKLLK
Sbjct: 147 LHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPDSVVQGRGQKQLIISTSDRKLLK 206

Query: 181 FILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRHPVIPKLYDPGPERKLRNLVTIA 240
           FILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRHPVIPKLYDPGPERKLRNLVTIA
Sbjct: 207 FILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRHPVIPKLYDPGPERKLRNLVTIA 266

Query: 241 TKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEIKDNHVEYYTMPFGKGWFAGRNL 300
           TKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEIKDNHVEYYTMPFGKGWFAGRNL
Sbjct: 267 TKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEIKDNHVEYYTMPFGKGWFAGRNL 326

Query: 301 AISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELDVVGGSVLGNVFQFKLLLEQSEN 360
           AISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELDVVGGSVLGNVFQFKLLLEQSEN
Sbjct: 327 AISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELDVVGGSVLGNVFQFKLLLEQSEN 386

Query: 361 GACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQRVGFDPRLQRVAHSEFFIDGLG 420
           GACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQRVGFDPRLQRVAHSEFFIDGLG
Sbjct: 387 GACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQRVGFDPRLQRVAHSEFFIDGLG 446

Query: 421 TLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSNTLTRVQFKLALHYFKNHLQCAA 480
           TLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSNTLTRVQFKLALHYFKNHLQCAA
Sbjct: 447 TLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSNTLTRVQFKLALHYFKNHLQCAA 506


>gi|227497758 beta-1,4-N-acetyl-galactosaminyl transferase 2 isoform
           c [Homo sapiens]
          Length = 480

 Score =  972 bits (2512), Expect = 0.0
 Identities = 480/480 (100%), Positives = 480/480 (100%)

Query: 1   MFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRNLFSYDGIWLFPKNQCKCEANKE 60
           MFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRNLFSYDGIWLFPKNQCKCEANKE
Sbjct: 1   MFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRNLFSYDGIWLFPKNQCKCEANKE 60

Query: 61  QGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPLLVQPNLPFGYPVHGVEVMP 120
           QGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPLLVQPNLPFGYPVHGVEVMP
Sbjct: 61  QGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPLLVQPNLPFGYPVHGVEVMP 120

Query: 121 LHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPDSVVQGRGQKQLIISTSDRKLLK 180
           LHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPDSVVQGRGQKQLIISTSDRKLLK
Sbjct: 121 LHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPDSVVQGRGQKQLIISTSDRKLLK 180

Query: 181 FILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRHPVIPKLYDPGPERKLRNLVTIA 240
           FILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRHPVIPKLYDPGPERKLRNLVTIA
Sbjct: 181 FILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRHPVIPKLYDPGPERKLRNLVTIA 240

Query: 241 TKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEIKDNHVEYYTMPFGKGWFAGRNL 300
           TKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEIKDNHVEYYTMPFGKGWFAGRNL
Sbjct: 241 TKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEIKDNHVEYYTMPFGKGWFAGRNL 300

Query: 301 AISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELDVVGGSVLGNVFQFKLLLEQSEN 360
           AISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELDVVGGSVLGNVFQFKLLLEQSEN
Sbjct: 301 AISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELDVVGGSVLGNVFQFKLLLEQSEN 360

Query: 361 GACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQRVGFDPRLQRVAHSEFFIDGLG 420
           GACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQRVGFDPRLQRVAHSEFFIDGLG
Sbjct: 361 GACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQRVGFDPRLQRVAHSEFFIDGLG 420

Query: 421 TLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSNTLTRVQFKLALHYFKNHLQCAA 480
           TLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSNTLTRVQFKLALHYFKNHLQCAA
Sbjct: 421 TLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSNTLTRVQFKLALHYFKNHLQCAA 480


>gi|227497754 beta-1,4-N-acetyl-galactosaminyl transferase 2 isoform
           a [Homo sapiens]
          Length = 566

 Score =  972 bits (2512), Expect = 0.0
 Identities = 480/480 (100%), Positives = 480/480 (100%)

Query: 1   MFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRNLFSYDGIWLFPKNQCKCEANKE 60
           MFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRNLFSYDGIWLFPKNQCKCEANKE
Sbjct: 87  MFGSMFLQAVFSSPKPELPSPAPGVQKLKLLPEERLRNLFSYDGIWLFPKNQCKCEANKE 146

Query: 61  QGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPLLVQPNLPFGYPVHGVEVMP 120
           QGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPLLVQPNLPFGYPVHGVEVMP
Sbjct: 147 QGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPLLVQPNLPFGYPVHGVEVMP 206

Query: 121 LHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPDSVVQGRGQKQLIISTSDRKLLK 180
           LHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPDSVVQGRGQKQLIISTSDRKLLK
Sbjct: 207 LHTVPIPGLQFEGPDAPVYEVTLTASLGTLNTLADVPDSVVQGRGQKQLIISTSDRKLLK 266

Query: 181 FILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRHPVIPKLYDPGPERKLRNLVTIA 240
           FILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRHPVIPKLYDPGPERKLRNLVTIA
Sbjct: 267 FILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRHPVIPKLYDPGPERKLRNLVTIA 326

Query: 241 TKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEIKDNHVEYYTMPFGKGWFAGRNL 300
           TKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEIKDNHVEYYTMPFGKGWFAGRNL
Sbjct: 327 TKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEIKDNHVEYYTMPFGKGWFAGRNL 386

Query: 301 AISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELDVVGGSVLGNVFQFKLLLEQSEN 360
           AISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELDVVGGSVLGNVFQFKLLLEQSEN
Sbjct: 387 AISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELDVVGGSVLGNVFQFKLLLEQSEN 446

Query: 361 GACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQRVGFDPRLQRVAHSEFFIDGLG 420
           GACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQRVGFDPRLQRVAHSEFFIDGLG
Sbjct: 447 GACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQRVGFDPRLQRVAHSEFFIDGLG 506

Query: 421 TLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSNTLTRVQFKLALHYFKNHLQCAA 480
           TLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSNTLTRVQFKLALHYFKNHLQCAA
Sbjct: 507 TLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYRSNTLTRVQFKLALHYFKNHLQCAA 566


>gi|4503893 beta-1,4-N-acetyl-galactosaminyl transferase 1 [Homo
           sapiens]
          Length = 533

 Score =  368 bits (944), Expect = e-102
 Identities = 214/493 (43%), Positives = 286/493 (58%), Gaps = 34/493 (6%)

Query: 12  SSPKPELP--SPAPGVQKLKLLPEERLRNLFSYDGIWLFPKNQCKCEAN---------KE 60
           S  +PELP  +P P    + +  +E++  L ++        N C CE++         K+
Sbjct: 45  SPRRPELPDLAPEPRYAHIPVRIKEQVVGLLAW--------NNCSCESSGGGLPLPFQKQ 96

Query: 61  QGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPLLVQPNLPFGYPVHGVEVMP 120
               +   A+  ++L A  A R+ EF+ F  R   P    L+   N P  YP+ GVEV P
Sbjct: 97  VRAIDLTKAFDPAELRAASATREQEFQAFLSRSQSPADQLLIAPANSPLQYPLQGVEVQP 156

Query: 121 LHTVPIPGLQFEGPDAP-VYEVTLTASLGTLNTLADVPDSVVQGRGQKQLIISTSDRKLL 179
           L ++ +PGL  +      VY+V LTASLGT +   +V    + G GQ  L + +     L
Sbjct: 157 LRSILVPGLSLQAASGQEVYQVNLTASLGTWDVAGEVTGVTLTGEGQADLTLVSPGLDQL 216

Query: 180 KFILQHVTYTSTGYQHQKVDIVSLESRSSVAKFPVTIRHPVIPKLYDPGP-----ERKLR 234
              LQ VTY+S  YQ    D V   +    A F + IRHP  P+LY PG      +  + 
Sbjct: 217 NRQLQLVTYSSRSYQTNTADTVRFSTEGHEAAFTIRIRHPPNPRLYPPGSLPQGAQYNIS 276

Query: 235 NLVTIATKTFLRPHKLMIMLRSIREYYPDLTVIVADDSQKPLEIKDNHVEYYTMPFGKGW 294
            LVTIATKTFLR  +L  ++ SIR +YP +TV++ADDS KP  +   +VE+Y MPFGKGW
Sbjct: 277 ALVTIATKTFLRYDRLRALITSIRRFYPTVTVVIADDSDKPERVSGPYVEHYLMPFGKGW 336

Query: 295 FAGRNLAISQVTTKYVLWVDDDFLFNEETKIEVLVDVLEKTELDVVGGSV---LGNVFQF 351
           FAGRNLA+SQVTTKYVLWVDDDF+F   T++E LVDVLE+T LD+VGG+V    G    +
Sbjct: 337 FAGRNLAVSQVTTKYVLWVDDDFVFTARTRLERLVDVLERTPLDLVGGAVREISGFATTY 396

Query: 352 KLLLEQSEN----GACLHKRMGFFQPLDGFPSCVVTSGVVNFFLAHTERLQRVGFDPRLQ 407
           + LL         G CL +R GF   L GFP CVVT GVVNFFLA T++++ VGFDPRL 
Sbjct: 397 RQLLSVEPGAPGLGNCLRQRRGFHHELVGFPGCVVTDGVVNFFLARTDKVREVGFDPRLS 456

Query: 408 RVAHSEFFIDGLGTLLVGSCPEVIIGHQSRSPVVDSELAALEKTYNTYR-SNTLTRVQF- 465
           RVAH EFF+DGLG+L VGSC +V++ H S+  +  +   A  +TY  YR   +L   Q  
Sbjct: 457 RVAHLEFFLDGLGSLRVGSCSDVVVDHASKLKLPWTSRDAGAETYARYRYPGSLDESQMA 516

Query: 466 KLALHYFKNHLQC 478
           K  L +FK+ LQC
Sbjct: 517 KHRLLFFKHRLQC 529


>gi|221316650 ephrin receptor EphA1 [Homo sapiens]
          Length = 976

 Score = 30.8 bits (68), Expect = 2.8
 Identities = 12/23 (52%), Positives = 14/23 (60%)

Query: 41  SYDGIWLFPKNQCKCEANKEQGG 63
           S DG WL P  +C CE   E+GG
Sbjct: 250 SPDGEWLVPVGRCHCEPGYEEGG 272


>gi|46370057 ring finger protein 216 isoform b [Homo sapiens]
          Length = 866

 Score = 29.6 bits (65), Expect = 6.3
 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 16/83 (19%)

Query: 56  EANKEQGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPL-LVQPNLP---FGY 111
           EA +EQ   N ++ + +   P  K       E  QR E LPRP+P  L QP +P   F +
Sbjct: 750 EAEEEQKRKNGENTFKRIGPPLEKP-----VEKVQRVEALPRPVPQNLPQPQMPPYAFAH 804

Query: 112 PVHGVEVM-------PLHTVPIP 127
           P   +  +       PL+  PIP
Sbjct: 805 PPFPLPPVRPVFNNFPLNMGPIP 827


>gi|46358403 ring finger protein 216 isoform a [Homo sapiens]
          Length = 923

 Score = 29.6 bits (65), Expect = 6.3
 Identities = 27/83 (32%), Positives = 38/83 (45%), Gaps = 16/83 (19%)

Query: 56  EANKEQGGYNFQDAYGQSDLPAVKARRQAEFEHFQRREGLPRPLPL-LVQPNLP---FGY 111
           EA +EQ   N ++ + +   P  K       E  QR E LPRP+P  L QP +P   F +
Sbjct: 807 EAEEEQKRKNGENTFKRIGPPLEKP-----VEKVQRVEALPRPVPQNLPQPQMPPYAFAH 861

Query: 112 PVHGVEVM-------PLHTVPIP 127
           P   +  +       PL+  PIP
Sbjct: 862 PPFPLPPVRPVFNNFPLNMGPIP 884


>gi|222136639 methylenetetrahydrofolate dehydrogenase 1 [Homo
           sapiens]
          Length = 935

 Score = 29.3 bits (64), Expect = 8.3
 Identities = 23/84 (27%), Positives = 36/84 (42%), Gaps = 13/84 (15%)

Query: 17  ELPSPAPGVQKLKLLPEERLR----NLFSYDGIWLFPKNQCKCEANKEQGGYNFQDAYGQ 72
           + PS    +  LKL  E+++R     ++  D I L P+ Q K E   +QG  N       
Sbjct: 807 QAPSSFQLLYDLKLPVEDKIRIIAQKIYGADDIELLPEAQHKAEVYTKQGFGN------- 859

Query: 73  SDLPAVKARRQAEFEHFQRREGLP 96
             LP   A+      H   ++G+P
Sbjct: 860 --LPICMAKTHLSLSHNPEQKGVP 881


>gi|82775371 coiled-coil domain containing 93 [Homo sapiens]
          Length = 631

 Score = 29.3 bits (64), Expect = 8.3
 Identities = 14/36 (38%), Positives = 22/36 (61%)

Query: 298 RNLAISQVTTKYVLWVDDDFLFNEETKIEVLVDVLE 333
           R+ ++SQ    Y L  DDDF+  +E  I+ +VD+ E
Sbjct: 139 RSYSVSQFQKTYSLPEDDDFIKRKEKAIKTVVDLSE 174


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.321    0.139    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 19,104,092
Number of Sequences: 37866
Number of extensions: 914059
Number of successful extensions: 2162
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 6
Number of HSP's successfully gapped in prelim test: 3
Number of HSP's that attempted gapping in prelim test: 2152
Number of HSP's gapped (non-prelim): 10
length of query: 480
length of database: 18,247,518
effective HSP length: 106
effective length of query: 374
effective length of database: 14,233,722
effective search space: 5323412028
effective search space used: 5323412028
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 64 (29.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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