Search of human proteins with 22748717

Search of human proteins with 22748717

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22748717 adenylosuccinate synthase like 1 isoform 2 [Homo
sapiens]
         (457 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22748717 adenylosuccinate synthase like 1 isoform 2 [Homo sap...   928   0.0  
gi|40316944 adenylosuccinate synthase like 1 isoform 1 [Homo sap...   803   0.0  
gi|34577063 adenylosuccinate synthase [Homo sapiens]                  715   0.0  
gi|42491362 IKK interacting protein isoform 2 [Homo sapiens]           37   0.049
gi|38454194 tubulin, gamma complex associated protein 4 [Homo sa...    31   2.7  

>gi|22748717 adenylosuccinate synthase like 1 isoform 2 [Homo
           sapiens]
          Length = 457

 Score =  928 bits (2399), Expect = 0.0
 Identities = 457/457 (100%), Positives = 457/457 (100%)

Query: 1   MSGTRASNDRPPGAGGVKRGRLQQEAAATGSRVTVVLGAQWGDEGKGKVVDLLATDADII 60
           MSGTRASNDRPPGAGGVKRGRLQQEAAATGSRVTVVLGAQWGDEGKGKVVDLLATDADII
Sbjct: 1   MSGTRASNDRPPGAGGVKRGRLQQEAAATGSRVTVVLGAQWGDEGKGKVVDLLATDADII 60

Query: 61  SRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKG 120
           SRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKG
Sbjct: 61  SRCQGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKG 120

Query: 121 LKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGL 180
           LKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGL
Sbjct: 121 LKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGL 180

Query: 181 RICDLLSDFDEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMY 240
           RICDLLSDFDEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMY
Sbjct: 181 RICDLLSDFDEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMY 240

Query: 241 EALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKA 300
           EALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKA
Sbjct: 241 EALHGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKA 300

Query: 301 YTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALA 360
           YTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALA
Sbjct: 301 YTTRVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALA 360

Query: 361 LTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWE 420
           LTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWE
Sbjct: 361 LTKLDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWE 420

Query: 421 DLPPQAQNYIRFVENHVGVAVKWVGVGKSRESMIQLF 457
           DLPPQAQNYIRFVENHVGVAVKWVGVGKSRESMIQLF
Sbjct: 421 DLPPQAQNYIRFVENHVGVAVKWVGVGKSRESMIQLF 457


>gi|40316944 adenylosuccinate synthase like 1 isoform 1 [Homo
           sapiens]
          Length = 500

 Score =  803 bits (2074), Expect = 0.0
 Identities = 393/394 (99%), Positives = 394/394 (100%)

Query: 64  QGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKD 123
           +GGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKD
Sbjct: 107 RGGNNAGHTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKGLKD 166

Query: 124 WEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRIC 183
           WEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRIC
Sbjct: 167 WEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRIC 226

Query: 184 DLLSDFDEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEAL 243
           DLLSDFDEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEAL
Sbjct: 227 DLLSDFDEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEAL 286

Query: 244 HGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTT 303
           HGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTT
Sbjct: 287 HGPPKKILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTT 346

Query: 304 RVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTK 363
           RVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTK
Sbjct: 347 RVGIGAFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTK 406

Query: 364 LDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLP 423
           LDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLP
Sbjct: 407 LDILDVLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLP 466

Query: 424 PQAQNYIRFVENHVGVAVKWVGVGKSRESMIQLF 457
           PQAQNYIRFVENHVGVAVKWVGVGKSRESMIQLF
Sbjct: 467 PQAQNYIRFVENHVGVAVKWVGVGKSRESMIQLF 500


>gi|34577063 adenylosuccinate synthase [Homo sapiens]
          Length = 456

 Score =  715 bits (1846), Expect = 0.0
 Identities = 345/449 (76%), Positives = 397/449 (88%), Gaps = 3/449 (0%)

Query: 12  PGAGGVKRGRL-QQEAAATGSRVTVVLGAQWGDEGKGKVVDLLATDADIISRCQGGNNAG 70
           P A  +  G   +  A   G+RVTVVLGAQWGDEGKGKVVDLLA DADI+ RCQGGNNAG
Sbjct: 8   PAASSLPNGDCGRPRARPGGNRVTVVLGAQWGDEGKGKVVDLLAQDADIVCRCQGGNNAG 67

Query: 71  HTVVVDGKEYDFHLLPSGIINTKAVSFIGNGVVIHLPGLFEEAEKNEKKG--LKDWEKRL 128
           HTVVVD  EYDFHLLPSGIIN    +FIGNGVVIHLPGLFEEAEKN +KG  L+ WEKRL
Sbjct: 68  HTVVVDSVEYDFHLLPSGIINPNVTAFIGNGVVIHLPGLFEEAEKNVQKGKGLEGWEKRL 127

Query: 129 IISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTGLRICDLLSD 188
           IISDRAH+VFDFHQA DG+QE QRQ Q GKN+GTTKKGIGP YSSKAAR+GLR+CDL+SD
Sbjct: 128 IISDRAHIVFDFHQAADGIQEQQRQEQAGKNLGTTKKGIGPVYSSKAARSGLRMCDLVSD 187

Query: 189 FDEFSSRFKNLAHQHQSMFPTLEIDIEGQLKRLKGFAERIRPMVRDGVYFMYEALHGPPK 248
           FD FS RFK LA+Q++S++PTLEIDIEG+L++LKG+ E+I+PMVRDGVYF+YEALHGPPK
Sbjct: 188 FDGFSERFKVLANQYKSIYPTLEIDIEGELQKLKGYMEKIKPMVRDGVYFLYEALHGPPK 247

Query: 249 KILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGIPPQNIGDVYGVVKAYTTRVGIG 308
           KILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLG+PPQN+G+VYGVVKAYTTRVGIG
Sbjct: 248 KILVEGANAALLDIDFGTYPFVTSSNCTVGGVCTGLGMPPQNVGEVYGVVKAYTTRVGIG 307

Query: 309 AFPTEQINEIGGLLQTRGHEWGVTTGRKRRCGWLDLMILRYAHMVNGFTALALTKLDILD 368
           AFPTEQ NEIG LLQTRG E+GVTTGRKRRCGWLDL++L+YAHM+NGFTALALTKLDILD
Sbjct: 308 AFPTEQDNEIGELLQTRGREFGVTTGRKRRCGWLDLVLLKYAHMINGFTALALTKLDILD 367

Query: 369 VLGEVKVGVSYKLNGKRIPYFPANQEMLQKVEVEYETLPGWKADTTGARRWEDLPPQAQN 428
           +  E+KVGV+YKL+G+ IP+ PANQE+L KVEV+Y+TLPGW  D + AR +++LP  AQN
Sbjct: 368 MFTEIKVGVAYKLDGEIIPHIPANQEVLNKVEVQYKTLPGWNTDISNARAFKELPVNAQN 427

Query: 429 YIRFVENHVGVAVKWVGVGKSRESMIQLF 457
           Y+RF+E+ + + VKW+GVGKSRESMIQLF
Sbjct: 428 YVRFIEDELQIPVKWIGVGKSRESMIQLF 456


>gi|42491362 IKK interacting protein isoform 2 [Homo sapiens]
          Length = 350

 Score = 36.6 bits (83), Expect = 0.049
 Identities = 34/134 (25%), Positives = 56/134 (41%), Gaps = 21/134 (15%)

Query: 120 GLKDWEKRLIISDRAHLVFDFHQAVDGLQEVQRQAQEGKNIGTTKKGIGPTYSSKAARTG 179
           GLK    +  I   + LV D     D +QE++ + ++ +    T K IG   SS   RT 
Sbjct: 169 GLKITSVKTDIRRISGLVTDVISLTDSVQELENKIEKVEK--NTVKNIGDLLSSSIDRTA 226

Query: 180 L-----------------RICDLLSDFDEFSSRFKNLAHQHQSMFPTLEI--DIEGQLKR 220
                              + +L SDFD+ + RF +L      +  T+    D++ ++  
Sbjct: 227 TLRKTASENSQRINSVKKTLTELKSDFDKHTDRFLSLEGDRAKVLKTVTFANDLKPKVYN 286

Query: 221 LKGFAERIRPMVRD 234
           LK    R+ P+V D
Sbjct: 287 LKKDFSRLEPLVND 300


>gi|38454194 tubulin, gamma complex associated protein 4 [Homo
           sapiens]
          Length = 666

 Score = 30.8 bits (68), Expect = 2.7
 Identities = 21/77 (27%), Positives = 36/77 (46%), Gaps = 5/77 (6%)

Query: 153 QAQEGKNIGTTKKGI-----GPTYSSKAARTGLRICDLLSDFDEFSSRFKNLAHQHQSMF 207
           Q  E +N+  T+KG        T++++  R   +    L DF++   R ++   +H    
Sbjct: 284 QMFENQNVNLTRKGSILKNQEDTFAAELHRLKQQPLFSLVDFEQVVDRIRSTVAEHLWKL 343

Query: 208 PTLEIDIEGQLKRLKGF 224
              E D+ GQLK +K F
Sbjct: 344 MVEESDLLGQLKIIKDF 360


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.138    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 17,632,271
Number of Sequences: 37866
Number of extensions: 771249
Number of successful extensions: 1577
Number of sequences better than 10.0: 5
Number of HSP's better than 10.0 without gapping: 3
Number of HSP's successfully gapped in prelim test: 2
Number of HSP's that attempted gapping in prelim test: 1573
Number of HSP's gapped (non-prelim): 5
length of query: 457
length of database: 18,247,518
effective HSP length: 106
effective length of query: 351
effective length of database: 14,233,722
effective search space: 4996036422
effective search space used: 4996036422
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.