BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] (1013 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] 2028 0.0 gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapi... 1786 0.0 gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] 1786 0.0 gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] 1786 0.0 gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapi... 1774 0.0 gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapi... 1589 0.0 gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] 1338 0.0 gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] 1328 0.0 gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sap... 376 e-104 gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sap... 376 e-104 gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sap... 376 e-104 gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sap... 376 e-104 gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Hom... 374 e-103 gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 374 e-103 gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Hom... 374 e-103 gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Hom... 374 e-103 gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Hom... 374 e-103 gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Hom... 374 e-103 gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Hom... 374 e-103 gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [H... 363 e-100 gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [... 363 e-100 gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [... 358 2e-98 gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [... 358 2e-98 gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo ... 343 5e-94 gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 ... 333 4e-91 gi|49249977 Na+/K+ -ATPase alpha 4 subunit isoform 2 [Homo sapiens] 287 3e-77 gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sap... 271 2e-72 gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sa... 267 4e-71 gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sa... 267 4e-71 gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sa... 229 1e-59 >gi|22748667 Na+/K+ -ATPase alpha 3 subunit [Homo sapiens] Length = 1013 Score = 2028 bits (5253), Expect = 0.0 Identities = 1013/1013 (100%), Positives = 1013/1013 (100%) Query: 1 MGDKKDDKDSPKKNKGKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQE 60 MGDKKDDKDSPKKNKGKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQE Sbjct: 1 MGDKKDDKDSPKKNKGKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQE 60 Query: 61 ILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNL 120 ILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNL Sbjct: 61 ILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNL 120 Query: 121 YLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDL 180 YLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDL Sbjct: 121 YLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDL 180 Query: 181 VEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCV 240 VEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCV Sbjct: 181 VEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCV 240 Query: 241 EGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILS 300 EGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILS Sbjct: 241 EGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILS 300 Query: 301 LILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGST 360 LILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGST Sbjct: 301 LILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGST 360 Query: 361 STICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNR 420 STICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNR Sbjct: 361 STICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNR 420 Query: 421 AVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQL 480 AVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQL Sbjct: 421 AVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQL 480 Query: 481 SIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGE 540 SIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGE Sbjct: 481 SIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGE 540 Query: 541 RVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAG 600 RVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAG Sbjct: 541 RVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAG 600 Query: 601 IKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDL 660 IKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDL Sbjct: 601 IKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDL 660 Query: 661 KDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADI 720 KDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADI Sbjct: 661 KDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADI 720 Query: 721 GVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPF 780 GVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPF Sbjct: 721 GVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPF 780 Query: 781 LLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLI 840 LLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLI Sbjct: 781 LLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLI 840 Query: 841 SMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQ 900 SMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQ Sbjct: 841 SMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQ 900 Query: 901 RKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSY 960 RKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSY Sbjct: 901 RKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSY 960 Query: 961 CPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013 CPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY Sbjct: 961 CPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013 >gi|237681109 Na+/K+ -ATPase alpha 1 subunit isoform c [Homo sapiens] Length = 1023 Score = 1786 bits (4625), Expect = 0.0 Identities = 879/1007 (87%), Positives = 951/1007 (94%) Query: 7 DKDSPKKNKGKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDG 66 ++ K KGK+ RD+D+LKKEV+M +HK+S++E+ RKY TD +GLT ++A EILARDG Sbjct: 17 EQGDKKGKKGKKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDG 76 Query: 67 PNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVL 126 PNALTPPPTTPEW+KFCRQLFGGFS+LLWIGAILCFLAY IQA TE++P DNLYLG+VL Sbjct: 77 PNALTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVL 136 Query: 127 AAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGG 186 +AVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIR GEKM +NAEEVVVGDLVE+KGG Sbjct: 137 SAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGG 196 Query: 187 DRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARG 246 DR+PADLRIISA+GCKVDNSSLTGESEPQTRSPD T++NPLETRNI FFSTNCVEGTARG Sbjct: 197 DRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARG 256 Query: 247 VVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYT 306 +VV TGDRTVMGRIATLASGLE G+TPIA EIEHFI +ITGVAVFLGVSFFILSLIL YT Sbjct: 257 IVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYT 316 Query: 307 WLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSD 366 WLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSD Sbjct: 317 WLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSD 376 Query: 367 KTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGG 426 KTGTLTQNRMTVAHMWFDNQIHEADTTE+QSG SFDK+S TW+ALS IAGLCNRAVF+ Sbjct: 377 KTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQAN 436 Query: 427 QDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETE 486 Q+N+P+LKR VAGDASESALLKCIEL GSVK MRER K+ EIPFNSTNKYQLSIH+ Sbjct: 437 QENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNP 496 Query: 487 DPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFC 546 + ++ ++LLVMKGAPERILDRCS+ILL GKEQPLDEE+K+AFQNAYLELGGLGERVLGFC Sbjct: 497 NTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFC 556 Query: 547 HYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMV 606 H +LP+EQFP+GF FD DDVNF DNLCFVGL+SMIDPPRAAVPDAVGKCRSAGIKVIMV Sbjct: 557 HLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMV 616 Query: 607 TGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSE 666 TGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACV+HG+DLKD TSE Sbjct: 617 TGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSE 676 Query: 667 QIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGI 726 Q+D+IL+ HTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGI Sbjct: 677 QLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGI 736 Query: 727 AGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMA 786 AGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFL+FI+A Sbjct: 737 AGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIA 796 Query: 787 NIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQ 846 NIPLPLGT+TILCIDLGTDMVPAISLAYE AESDIMKRQPRNP+TDKLVNERLISMAYGQ Sbjct: 797 NIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQ 856 Query: 847 IGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEF 906 IGMIQALGGFF+YFVILAENGFLP +L+G+R++WDDR +ND+EDSYGQQWTYEQRK+VEF Sbjct: 857 IGMIQALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEF 916 Query: 907 TCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDV 966 TCHTAFFVSIVVVQWADL+ICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGM V Sbjct: 917 TCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGV 976 Query: 967 ALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013 ALRMYPLKP+WWFCAFPYS LIFVYDE+RKLI+RR PGGWVEKETYY Sbjct: 977 ALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 1023 >gi|4502271 Na+/K+ -ATPase alpha 2 subunit proprotein [Homo sapiens] Length = 1020 Score = 1786 bits (4625), Expect = 0.0 Identities = 885/1001 (88%), Positives = 949/1001 (94%), Gaps = 2/1001 (0%) Query: 13 KNKGKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTP 72 K K KE+ +LD+LKKEVAM +HK+S++E+ RKY D +GLT+ +AQ++LARDGPNALTP Sbjct: 22 KKKQKEK-ELDELKKEVAMDDHKLSLDELGRKYQVDLSKGLTNQRAQDVLARDGPNALTP 80 Query: 73 PPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVII 132 PPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQA ED+PS DNLYLG+VLAAVVI+ Sbjct: 81 PPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAAMEDEPSNDNLYLGVVLAAVVIV 140 Query: 133 TGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPAD 192 TGCFSYYQEAKSSKIM+SFKNMVPQQALVIREGEKMQ+NAEEVVVGDLVE+KGGDRVPAD Sbjct: 141 TGCFSYYQEAKSSKIMDSFKNMVPQQALVIREGEKMQINAEEVVVGDLVEVKGGDRVPAD 200 Query: 193 LRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATG 252 LRIIS+HGCKVDNSSLTGESEPQTRSP+ TH+NPLETRNI FFSTNCVEGTARG+V+ATG Sbjct: 201 LRIISSHGCKVDNSSLTGESEPQTRSPEFTHENPLETRNICFFSTNCVEGTARGIVIATG 260 Query: 253 DRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVI 312 DRTVMGRIATLASGLEVG+TPIA+EIEHFIQLITGVAVFLGVSFF+LSLILGY+WLEAVI Sbjct: 261 DRTVMGRIATLASGLEVGRTPIAMEIEHFIQLITGVAVFLGVSFFVLSLILGYSWLEAVI 320 Query: 313 FLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLT 372 FLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLT Sbjct: 321 FLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLT 380 Query: 373 QNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPV 432 QNRMTVAHMWFDNQIHEADTTEDQSG +FDK S TW ALS IAGLCNRAVFK GQ+NI V Sbjct: 381 QNRMTVAHMWFDNQIHEADTTEDQSGATFDKRSPTWTALSRIAGLCNRAVFKAGQENISV 440 Query: 433 LKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNR 492 KRD AGDASESALLKCIELS GSV+ MR+RN KVAEIPFNSTNKYQLSIHE ED + Sbjct: 441 SKRDTAGDASESALLKCIELSCGSVRKMRDRNPKVAEIPFNSTNKYQLSIHERED-SPQS 499 Query: 493 YLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPE 552 ++LVMKGAPERILDRCSTIL+QGKE PLD+EM++AFQNAY+ELGGLGERVLGFC LP Sbjct: 500 HVLVMKGAPERILDRCSTILVQGKEIPLDKEMQDAFQNAYMELGGLGERVLGFCQLNLPS 559 Query: 553 EQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPI 612 +FP+GF FD D++NF T+ LCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPI Sbjct: 560 GKFPRGFKFDTDELNFPTEKLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPI 619 Query: 613 TAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEIL 672 TAKAIAKGVGIISEGNETVEDIAARLNIP+SQVNPR+AKACV+HG+DLKD TSEQ+DEIL Sbjct: 620 TAKAIAKGVGIISEGNETVEDIAARLNIPMSQVNPREAKACVVHGSDLKDMTSEQLDEIL 679 Query: 673 QNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVS 732 +NHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIG+AMGI+GSDVS Sbjct: 680 KNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGIAMGISGSDVS 739 Query: 733 KQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPL 792 KQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFI+ANIPLPL Sbjct: 740 KQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIIANIPLPL 799 Query: 793 GTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQA 852 GT+TILCIDLGTDMVPAISLAYEAAESDIMKRQPRN +TDKLVNERLISMAYGQIGMIQA Sbjct: 800 GTVTILCIDLGTDMVPAISLAYEAAESDIMKRQPRNSQTDKLVNERLISMAYGQIGMIQA 859 Query: 853 LGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAF 912 LGGFF+YFVILAENGFLP L+GIRL+WDDRT+NDLEDSYGQ+WTYEQRKVVEFTCHTAF Sbjct: 860 LGGFFTYFVILAENGFLPSRLLGIRLDWDDRTMNDLEDSYGQEWTYEQRKVVEFTCHTAF 919 Query: 913 FVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYP 972 F SIVVVQWADLIICKTRRNSVFQQGMKNKILIFGL EETALAAFLSYCPGM VALRMYP Sbjct: 920 FASIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLLEETALAAFLSYCPGMGVALRMYP 979 Query: 973 LKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013 LK +WWFCAFPYS LIF+YDE+RKLILRR PGGWVEKETYY Sbjct: 980 LKVTWWFCAFPYSLLIFIYDEVRKLILRRYPGGWVEKETYY 1020 >gi|21361181 Na+/K+ -ATPase alpha 1 subunit isoform a [Homo sapiens] Length = 1023 Score = 1786 bits (4625), Expect = 0.0 Identities = 879/1007 (87%), Positives = 951/1007 (94%) Query: 7 DKDSPKKNKGKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDG 66 ++ K KGK+ RD+D+LKKEV+M +HK+S++E+ RKY TD +GLT ++A EILARDG Sbjct: 17 EQGDKKGKKGKKDRDMDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDG 76 Query: 67 PNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVL 126 PNALTPPPTTPEW+KFCRQLFGGFS+LLWIGAILCFLAY IQA TE++P DNLYLG+VL Sbjct: 77 PNALTPPPTTPEWIKFCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVL 136 Query: 127 AAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGG 186 +AVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIR GEKM +NAEEVVVGDLVE+KGG Sbjct: 137 SAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGG 196 Query: 187 DRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARG 246 DR+PADLRIISA+GCKVDNSSLTGESEPQTRSPD T++NPLETRNI FFSTNCVEGTARG Sbjct: 197 DRIPADLRIISANGCKVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARG 256 Query: 247 VVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYT 306 +VV TGDRTVMGRIATLASGLE G+TPIA EIEHFI +ITGVAVFLGVSFFILSLIL YT Sbjct: 257 IVVYTGDRTVMGRIATLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYT 316 Query: 307 WLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSD 366 WLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSD Sbjct: 317 WLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSD 376 Query: 367 KTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGG 426 KTGTLTQNRMTVAHMWFDNQIHEADTTE+QSG SFDK+S TW+ALS IAGLCNRAVF+ Sbjct: 377 KTGTLTQNRMTVAHMWFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQAN 436 Query: 427 QDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETE 486 Q+N+P+LKR VAGDASESALLKCIEL GSVK MRER K+ EIPFNSTNKYQLSIH+ Sbjct: 437 QENLPILKRAVAGDASESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNP 496 Query: 487 DPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFC 546 + ++ ++LLVMKGAPERILDRCS+ILL GKEQPLDEE+K+AFQNAYLELGGLGERVLGFC Sbjct: 497 NTSEPQHLLVMKGAPERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFC 556 Query: 547 HYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMV 606 H +LP+EQFP+GF FD DDVNF DNLCFVGL+SMIDPPRAAVPDAVGKCRSAGIKVIMV Sbjct: 557 HLFLPDEQFPEGFQFDTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMV 616 Query: 607 TGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSE 666 TGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACV+HG+DLKD TSE Sbjct: 617 TGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSE 676 Query: 667 QIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGI 726 Q+D+IL+ HTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGI Sbjct: 677 QLDDILKYHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGI 736 Query: 727 AGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMA 786 AGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFL+FI+A Sbjct: 737 AGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIA 796 Query: 787 NIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQ 846 NIPLPLGT+TILCIDLGTDMVPAISLAYE AESDIMKRQPRNP+TDKLVNERLISMAYGQ Sbjct: 797 NIPLPLGTVTILCIDLGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQ 856 Query: 847 IGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEF 906 IGMIQALGGFF+YFVILAENGFLP +L+G+R++WDDR +ND+EDSYGQQWTYEQRK+VEF Sbjct: 857 IGMIQALGGFFTYFVILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEF 916 Query: 907 TCHTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDV 966 TCHTAFFVSIVVVQWADL+ICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGM V Sbjct: 917 TCHTAFFVSIVVVQWADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGV 976 Query: 967 ALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013 ALRMYPLKP+WWFCAFPYS LIFVYDE+RKLI+RR PGGWVEKETYY Sbjct: 977 ALRMYPLKPTWWFCAFPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 1023 >gi|237681111 Na+/K+ -ATPase alpha 1 subunit isoform d [Homo sapiens] Length = 992 Score = 1774 bits (4595), Expect = 0.0 Identities = 873/992 (88%), Positives = 942/992 (94%) Query: 22 LDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVK 81 +D+LKKEV+M +HK+S++E+ RKY TD +GLT ++A EILARDGPNALTPPPTTPEW+K Sbjct: 1 MDELKKEVSMDDHKLSLDELHRKYGTDLSRGLTSARAAEILARDGPNALTPPPTTPEWIK 60 Query: 82 FCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQE 141 FCRQLFGGFS+LLWIGAILCFLAY IQA TE++P DNLYLG+VL+AVVIITGCFSYYQE Sbjct: 61 FCRQLFGGFSMLLWIGAILCFLAYSIQAATEEEPQNDNLYLGVVLSAVVIITGCFSYYQE 120 Query: 142 AKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGC 201 AKSSKIMESFKNMVPQQALVIR GEKM +NAEEVVVGDLVE+KGGDR+PADLRIISA+GC Sbjct: 121 AKSSKIMESFKNMVPQQALVIRNGEKMSINAEEVVVGDLVEVKGGDRIPADLRIISANGC 180 Query: 202 KVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIA 261 KVDNSSLTGESEPQTRSPD T++NPLETRNI FFSTNCVEGTARG+VV TGDRTVMGRIA Sbjct: 181 KVDNSSLTGESEPQTRSPDFTNENPLETRNIAFFSTNCVEGTARGIVVYTGDRTVMGRIA 240 Query: 262 TLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVAN 321 TLASGLE G+TPIA EIEHFI +ITGVAVFLGVSFFILSLIL YTWLEAVIFLIGIIVAN Sbjct: 241 TLASGLEGGQTPIAAEIEHFIHIITGVAVFLGVSFFILSLILEYTWLEAVIFLIGIIVAN 300 Query: 322 VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 381 VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM Sbjct: 301 VPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHM 360 Query: 382 WFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDA 441 WFDNQIHEADTTE+QSG SFDK+S TW+ALS IAGLCNRAVF+ Q+N+P+LKR VAGDA Sbjct: 361 WFDNQIHEADTTENQSGVSFDKTSATWLALSRIAGLCNRAVFQANQENLPILKRAVAGDA 420 Query: 442 SESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKGAP 501 SESALLKCIEL GSVK MRER K+ EIPFNSTNKYQLSIH+ + ++ ++LLVMKGAP Sbjct: 421 SESALLKCIELCCGSVKEMRERYAKIVEIPFNSTNKYQLSIHKNPNTSEPQHLLVMKGAP 480 Query: 502 ERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAF 561 ERILDRCS+ILL GKEQPLDEE+K+AFQNAYLELGGLGERVLGFCH +LP+EQFP+GF F Sbjct: 481 ERILDRCSSILLHGKEQPLDEELKDAFQNAYLELGGLGERVLGFCHLFLPDEQFPEGFQF 540 Query: 562 DCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 621 D DDVNF DNLCFVGL+SMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV Sbjct: 541 DTDDVNFPIDNLCFVGLISMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGV 600 Query: 622 GIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFA 681 GIISEGNETVEDIAARLNIPVSQVNPRDAKACV+HG+DLKD TSEQ+D+IL+ HTEIVFA Sbjct: 601 GIISEGNETVEDIAARLNIPVSQVNPRDAKACVVHGSDLKDMTSEQLDDILKYHTEIVFA 660 Query: 682 RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 741 RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL Sbjct: 661 RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 720 Query: 742 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCID 801 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFL+FI+ANIPLPLGT+TILCID Sbjct: 721 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLIFIIANIPLPLGTVTILCID 780 Query: 802 LGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFV 861 LGTDMVPAISLAYE AESDIMKRQPRNP+TDKLVNERLISMAYGQIGMIQALGGFF+YFV Sbjct: 781 LGTDMVPAISLAYEQAESDIMKRQPRNPKTDKLVNERLISMAYGQIGMIQALGGFFTYFV 840 Query: 862 ILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAFFVSIVVVQW 921 ILAENGFLP +L+G+R++WDDR +ND+EDSYGQQWTYEQRK+VEFTCHTAFFVSIVVVQW Sbjct: 841 ILAENGFLPIHLLGLRVDWDDRWINDVEDSYGQQWTYEQRKIVEFTCHTAFFVSIVVVQW 900 Query: 922 ADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPSWWFCA 981 ADL+ICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGM VALRMYPLKP+WWFCA Sbjct: 901 ADLVICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMGVALRMYPLKPTWWFCA 960 Query: 982 FPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013 FPYS LIFVYDE+RKLI+RR PGGWVEKETYY Sbjct: 961 FPYSLLIFVYDEVRKLIIRRRPGGWVEKETYY 992 >gi|153946397 Na+/K+ -ATPase alpha 4 subunit isoform 1 [Homo sapiens] Length = 1029 Score = 1589 bits (4114), Expect = 0.0 Identities = 787/997 (78%), Positives = 884/997 (88%), Gaps = 2/997 (0%) Query: 17 KERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTT 76 K++R++++LKKEV M +HK+++EE+ KY+ D +G +H +A+EIL R GPN +TPPPTT Sbjct: 35 KQKRNMEELKKEVVMDDHKLTLEELSTKYSVDLTKGHSHQRAKEILTRGGPNTVTPPPTT 94 Query: 77 PEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCF 136 PEWVKFC+QLFGGFS+LLW GAILCF+AY IQ ++P+ DNLYL IVL+ VVI+TGCF Sbjct: 95 PEWVKFCKQLFGGFSLLLWTGAILCFVAYSIQIYFNEEPTKDNLYLSIVLSVVVIVTGCF 154 Query: 137 SYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRII 196 SYYQEAKSSKIMESFKNMVPQQALVIR GEKMQ+N +EVV+GDLVEIKGGDRVPADLR+I Sbjct: 155 SYYQEAKSSKIMESFKNMVPQQALVIRGGEKMQINVQEVVLGDLVEIKGGDRVPADLRLI 214 Query: 197 SAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTV 256 SA GCKVDNSSLTGESEPQ+RSPD TH+NPLETRNI FFSTNCVEGTARG+V+ATGD TV Sbjct: 215 SAQGCKVDNSSLTGESEPQSRSPDFTHENPLETRNICFFSTNCVEGTARGIVIATGDSTV 274 Query: 257 MGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIG 316 MGRIA+L SGL VG+TPIA EIEHFI LIT VAVFLGV+FF LSL+LGY WLEA+IFLIG Sbjct: 275 MGRIASLTSGLAVGQTPIAAEIEHFIHLITVVAVFLGVTFFALSLLLGYGWLEAIIFLIG 334 Query: 317 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 376 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM Sbjct: 335 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 394 Query: 377 TVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRD 436 TVAHMWFD ++EADTTE+Q+G +F KSS TW L+ IAGLCNRA FK Q+ +P+ KR Sbjct: 395 TVAHMWFDMTVYEADTTEEQTGKTFTKSSDTWFMLARIAGLCNRADFKANQEILPIAKRA 454 Query: 437 VAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLV 496 GDASESALLK IE S SV MRE+N KVAEIPFNSTNKYQ+SIH ED + ++L+ Sbjct: 455 TTGDASESALLKFIEQSYSSVAEMREKNPKVAEIPFNSTNKYQMSIHLREDSSQT-HVLM 513 Query: 497 MKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFP 556 MKGAPERIL+ CST LL G+E +++EMKEAFQNAYLELGGLGERVLGFC LP F Sbjct: 514 MKGAPERILEFCSTFLLNGQEYSMNDEMKEAFQNAYLELGGLGERVLGFCFLNLPSS-FS 572 Query: 557 KGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKA 616 KGF F+ D++NF DNLCFVGL+SMIDPPRAAVPDAV KCRSAGIKVIMVTGDHPITAKA Sbjct: 573 KGFPFNTDEINFPMDNLCFVGLISMIDPPRAAVPDAVSKCRSAGIKVIMVTGDHPITAKA 632 Query: 617 IAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHT 676 IAKGVGIISEG ET E++AARL IP+S+V+ AKA V+HG +LKD S+Q+D+ILQNH Sbjct: 633 IAKGVGIISEGTETAEEVAARLKIPISKVDASAAKAIVVHGAELKDIQSKQLDQILQNHP 692 Query: 677 EIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAA 736 EIVFARTSPQQKLIIVEGCQR GA+VAVTGDGVNDSPALKKADIG+AMGI+GSDVSKQAA Sbjct: 693 EIVFARTSPQQKLIIVEGCQRLGAVVAVTGDGVNDSPALKKADIGIAMGISGSDVSKQAA 752 Query: 737 DMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTIT 796 DMILLDDNFASIVTGVEEGRLIFDNLKKSI YTLTSNIPEITPFL+FI+ IPLPLGTIT Sbjct: 753 DMILLDDNFASIVTGVEEGRLIFDNLKKSIMYTLTSNIPEITPFLMFIILGIPLPLGTIT 812 Query: 797 ILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGF 856 ILCIDLGTDMVPAISLAYE+AESDIMKR PRNP+TD LVN RLI MAYGQIGMIQAL GF Sbjct: 813 ILCIDLGTDMVPAISLAYESAESDIMKRLPRNPKTDNLVNHRLIGMAYGQIGMIQALAGF 872 Query: 857 FSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTCHTAFFVSI 916 F+YFVILAENGF P +L+GIRL+W+D+ +NDLEDSYGQQWTYEQRKVVEFTC TAFFV+I Sbjct: 873 FTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTCQTAFFVTI 932 Query: 917 VVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVALRMYPLKPS 976 VVVQWADLII KTRRNS+FQQGM+NK+LIFG+ EET LAAFLSY PGMDVALRMYPLK + Sbjct: 933 VVVQWADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVALRMYPLKIT 992 Query: 977 WWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013 WW CA PYS LIFVYDEIRKL++R++P GWVE+ETYY Sbjct: 993 WWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 1029 >gi|51944966 hydrogen/potassium-exchanging ATPase 4A [Homo sapiens] Length = 1035 Score = 1338 bits (3463), Expect = 0.0 Identities = 656/1014 (64%), Positives = 801/1014 (78%), Gaps = 1/1014 (0%) Query: 1 MGDKKDDKDSPKKNKGKERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQE 60 M K K GK + L+++KKE+ + +H++SV E+ +KY T +GL+ S A E Sbjct: 22 MAAKMSKKKKAGGGGGKRKEKLENMKKEMEINDHQLSVAELEQKYQTSATKGLSASLAAE 81 Query: 61 ILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNL 120 +L RDGPNAL PP TPE+VKF RQL GG L+W+ A +C +A+ IQA D + DNL Sbjct: 82 LLLRDGPNALRPPRGTPEYVKFARQLAGGLQCLMWVAAAICLIAFAIQASEGDLTTDDNL 141 Query: 121 YLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDL 180 YL I L AVV++TGCF YYQE KS+ I+ SFKN+VPQQA VIR+G+K Q+NA+++VVGDL Sbjct: 142 YLAIALIAVVVVTGCFGYYQEFKSTNIIASFKNLVPQQATVIRDGDKFQINADQLVVGDL 201 Query: 181 VEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFFSTNCV 240 VE+KGGDRVPAD+RI++A GCKVDNSSLTGESEPQTRSP+CTH++PLETRNI FFST C+ Sbjct: 202 VEMKGGDRVPADIRILAAQGCKVDNSSLTGESEPQTRSPECTHESPLETRNIAFFSTMCL 261 Query: 241 EGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILS 300 EGT +G+VV TGDRT++GRIA+LASG+E KTPIAIEIEHF+ +I G+A+ G +FFI++ Sbjct: 262 EGTVQGLVVNTGDRTIIGRIASLASGVENEKTPIAIEIEHFVDIIAGLAILFGATFFIVA 321 Query: 301 LILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGST 360 + +GYT+L A++F + I+VA VPEGLLATVTVCL+LTAKR+A KNC+VKNLEAVETLGST Sbjct: 322 MCIGYTFLRAMVFFMAIVVAYVPEGLLATVTVCLSLTAKRLASKNCVVKNLEAVETLGST 381 Query: 361 STICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNR 420 S ICSDKTGTLTQNRMTV+H+WFDN IH ADTTEDQSG +FD+SS TW AL + LCNR Sbjct: 382 SVICSDKTGTLTQNRMTVSHLWFDNHIHTADTTEDQSGQTFDQSSETWRALCRVLTLCNR 441 Query: 421 AVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQL 480 A FK GQD +PV KR V GDASE+ALLK EL+ G+ R+R KV EIPFNSTNK+QL Sbjct: 442 AAFKSGQDAVPVPKRIVIGDASETALLKFSELTLGNAMGYRDRFPKVCEIPFNSTNKFQL 501 Query: 481 SIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGE 540 SIH EDP D R+LLVMKGAPER+L+RCS+IL++G+E PLDE+ +EAFQ AYL LGGLGE Sbjct: 502 SIHTLEDPRDPRHLLVMKGAPERVLERCSSILIKGQELPLDEQWREAFQTAYLSLGGLGE 561 Query: 541 RVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAG 600 RVLGFC YL E+ +P G+AFD + +NF + LCF GL+SMIDPPRA VPDAV KCR+AG Sbjct: 562 RVLGFCQLYLNEKDYPPGYAFDVEAMNFPSSGLCFAGLVSMIDPPRATVPDAVLKCRTAG 621 Query: 601 IKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDL 660 I+VIMVTGDHPITAKAIA VGIISEG+ETVEDIAARL +PV QVN +DA+ACVI+G L Sbjct: 622 IRVIMVTGDHPITAKAIAASVGIISEGSETVEDIAARLRVPVDQVNRKDARACVINGMQL 681 Query: 661 KDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADI 720 KD ++ E L+ H E+VFARTSPQQKL+IVE CQR GAIVAVTGDGVNDSPALKKADI Sbjct: 682 KDMDPSELVEALRTHPEMVFARTSPQQKLVIVESCQRLGAIVAVTGDGVNDSPALKKADI 741 Query: 721 GVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPF 780 GVAMGIAGSD +K AADMILLDDNFASIVTGVE+GRLIFDNLKKSIAYTLT NIPE+TP+ Sbjct: 742 GVAMGIAGSDAAKNAADMILLDDNFASIVTGVEQGRLIFDNLKKSIAYTLTKNIPELTPY 801 Query: 781 LLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLI 840 L++I ++PLPLG ITIL I+L TD+ P++SLAYE AESDIM +PRNP+ D+LVNE L Sbjct: 802 LIYITVSVPLPLGCITILFIELCTDIFPSVSLAYEKAESDIMHLRPRNPKRDRLVNEPLA 861 Query: 841 SMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQ 900 + +Y QIG IQ+ GF YF +A+ G+ P VG+R W+D + DL+DSYGQ+WT+ Q Sbjct: 862 AYSYFQIGAIQSFAGFTDYFTAMAQEGWFPLLCVGLRAQWEDHHLQDLQDSYGQEWTFGQ 921 Query: 901 RKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQG-MKNKILIFGLFEETALAAFLS 959 R ++TC+T FF+SI V Q AD++I KTRR S FQQG +NKIL+ + + + FL Sbjct: 922 RLYQQYTCYTVFFISIEVCQIADVLIRKTRRLSAFQQGFFRNKILVIAIVFQVCIGCFLC 981 Query: 960 YCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013 YCPGM P++ WW PY LIFVYDEIRKL +R PG W ++E YY Sbjct: 982 YCPGMPNIFNFMPIRFQWWLVPLPYGILIFVYDEIRKLGVRCCPGSWWDQELYY 1035 >gi|83700225 hydrogen/potassium-exchanging ATPase 12A [Homo sapiens] Length = 1039 Score = 1328 bits (3436), Expect = 0.0 Identities = 654/1019 (64%), Positives = 816/1019 (80%), Gaps = 9/1019 (0%) Query: 4 KKDDKDSPKKNKG--------KERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTH 55 K D D +K +G K++ ++ +KE+ + +HK+S E+ KY TD + GL+ Sbjct: 21 KTDKGDGKEKYRGLKNNCLELKKKNHKEEFQKELHLDDHKLSNRELEEKYGTDIIMGLSS 80 Query: 56 SKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDP 115 ++A E+LARDGPN+LTPP TPE VKF +Q+ GGFSILLW+GA LC++AYGIQ ++ Sbjct: 81 TRAAELLARDGPNSLTPPKQTPEIVKFLKQMVGGFSILLWVGAFLCWIAYGIQYSSDKSA 140 Query: 116 SGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEV 175 S +N+YLG VL VVI+TG F+YYQEAKS+ IM SF M+PQQALVIR+ EK + +E++ Sbjct: 141 SLNNVYLGCVLGLVVILTGIFAYYQEAKSTNIMSSFNKMIPQQALVIRDSEKKTIPSEQL 200 Query: 176 VVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNITFF 235 VVGD+VE+KGGD++PAD+R++S+ GC+VDNSSLTGESEPQ RS + TH+NPLET+NI F+ Sbjct: 201 VVGDIVEVKGGDQIPADIRVLSSQGCRVDNSSLTGESEPQPRSSEFTHENPLETKNICFY 260 Query: 236 STNCVEGTARGVVVATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVS 295 ST C+EGT G+V+ TGDRT++G IA+LASG+ KTPIAIEIEHF+ ++ GVAV +G+ Sbjct: 261 STTCLEGTVTGMVINTGDRTIIGHIASLASGVGNEKTPIAIEIEHFVHIVAGVAVSIGIL 320 Query: 296 FFILSLILGYTWLEAVIFLIGIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVE 355 FFI+++ L Y L+++IFLIGIIVANVPEGLLATVTV L+LTAKRMA+KNCLVKNLEAVE Sbjct: 321 FFIIAVSLKYQVLDSIIFLIGIIVANVPEGLLATVTVTLSLTAKRMAKKNCLVKNLEAVE 380 Query: 356 TLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIA 415 TLGSTS ICSDKTGTLTQNRMTVAH+WFDNQI ADT+ED S FD+SS TW +LS I Sbjct: 381 TLGSTSIICSDKTGTLTQNRMTVAHLWFDNQIFVADTSEDHSNQVFDQSSRTWASLSKII 440 Query: 416 GLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCIELSSGSVKLMRERNKKVAEIPFNST 475 LCNRA FK GQ+N+P++K+ V GDASE+ALLK E+ G V +R+RN+KVAEIPFNST Sbjct: 441 TLCNRAEFKPGQENVPIMKKAVIGDASETALLKFSEVILGDVMEIRKRNRKVAEIPFNST 500 Query: 476 NKYQLSIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLEL 535 NK+QLSIHE +DP+ R+L+VMKGAPERIL++CSTI++ G+E PLD+ + F AY+EL Sbjct: 501 NKFQLSIHEMDDPHGKRFLMVMKGAPERILEKCSTIMINGEEHPLDKSTAKTFHTAYMEL 560 Query: 536 GGLGERVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGK 595 GGLGERVLGFCH YLP ++FP+ ++FD D +NF T NLCFVGL+SMIDPPR+ VPDAV K Sbjct: 561 GGLGERVLGFCHLYLPADEFPETYSFDIDAMNFPTSNLCFVGLLSMIDPPRSTVPDAVTK 620 Query: 596 CRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVI 655 CRSAGIKVIMVTGDHPITAKAIAK VGIIS +ETVEDIA RLNI V QVN RDAKA V+ Sbjct: 621 CRSAGIKVIMVTGDHPITAKAIAKSVGIISANSETVEDIAHRLNIAVEQVNKRDAKAAVV 680 Query: 656 HGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPAL 715 G +LKD +SEQ+DEIL N+ EIVFARTSPQQKLIIVEGCQRQ A+VAVTGDGVNDSPAL Sbjct: 681 TGMELKDMSSEQLDEILANYQEIVFARTSPQQKLIIVEGCQRQDAVVAVTGDGVNDSPAL 740 Query: 716 KKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIP 775 KKADIG+AMGIAGSD +K AADM+LLDDNFASIVTGVEEGRLIFDNLKK+IAY+LT NI Sbjct: 741 KKADIGIAMGIAGSDAAKNAADMVLLDDNFASIVTGVEEGRLIFDNLKKTIAYSLTKNIA 800 Query: 776 EITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLV 835 E+ PFL++I+ +PLP+GTITIL IDLGTD++P+I+LAYE AESDIM R+PR+ D+LV Sbjct: 801 ELCPFLIYIIVGLPLPIGTITILFIDLGTDIIPSIALAYEKAESDIMNRKPRHKNKDRLV 860 Query: 836 NERLISMAYGQIGMIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQ 895 N+ L +Y IG++QALG F YF + A+ GFLP L+ +R+ W+ VNDL+DSYGQ+ Sbjct: 861 NQPLAVYSYLHIGLMQALGAFLVYFTVYAQEGFLPRTLINLRVEWEKDYVNDLKDSYGQE 920 Query: 896 WTYEQRKVVEFTCHTAFFVSIVVVQWADLIICKTRRNSVFQQGM-KNKILIFGLFEETAL 954 WT QR+ +E+T +TAFFV I+V Q ADLII KTRRNS+FQQG+ +NK++ G+ + + Sbjct: 921 WTRYQREYLEWTGYTAFFVGILVQQIADLIIRKTRRNSIFQQGLFRNKVIWVGITSQIII 980 Query: 955 AAFLSYCPGMDVALRMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013 LSY G AL L+ +WF A P++ LI+VYDE+RKL +R PG W +K YY Sbjct: 981 GLILSYGLGSVTALSFTMLRAQYWFVAVPHAILIWVYDEVRKLFIRLYPGSWWDKNMYY 1039 >gi|48762691 calcium-transporting ATPase 2C1 isoform 1b [Homo sapiens] Length = 939 Score = 376 bits (965), Expect = e-104 Identities = 269/849 (31%), Positives = 422/849 (49%), Gaps = 84/849 (9%) Query: 35 KMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILL 94 ++ V EV D GL + A G N P W K+ Q +LL Sbjct: 28 ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87 Query: 95 WIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNM 154 A++ L + DD + I +A ++++T F QE +S K +E + Sbjct: 88 LASAVISVLMHQF-----DDA------VSITVAILIVVTVAF--VQEYRSEKSLEELSKL 134 Query: 155 VPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEP 214 VP + +REG+ A ++V GD V + GDRVPADLR+ A +D SSLTGE+ P Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194 Query: 215 QTR----SPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVG 270 ++ P T+ + NI F T G A+GVV+ TG+ + G + + E Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254 Query: 271 KTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVANVPEGLLATV 330 KTP+ ++ + ++ + + ++ +LG LE + + VA +PEGL V Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314 Query: 331 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEA 390 TV L L RM +K +VK L VETLG + ICSDKTGTLT+N MTV H++ + +H Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374 Query: 391 DTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFK----GGQDNIPVLKRD-VAGDASESA 445 T G +++ V + G N AV + G N V++ + + G +E A Sbjct: 375 VT-----GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGA 429 Query: 446 LLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQL--SIHETEDPNDNRYLLVMKGAPER 503 L+ + + G L ++ +K AE PF+S K+ +H T+ D + MKGA E+ Sbjct: 430 LI-ALAMKMGLDGLQQDYIRK-AEYPFSSEQKWMAVKCVHRTQQ--DRPEICFMKGAYEQ 485 Query: 504 ILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDC 563 ++ C+T +G+ L ++ ++ +Q +G G RVL PE Sbjct: 486 VIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASG--PE----------- 532 Query: 564 DDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 623 L F+GL+ +IDPPR V +AV ++G+ + M+TGD TA AIA +G+ Sbjct: 533 ------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586 Query: 624 ISEGNETV--EDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFA 681 S+ +++V E+I A +SQ+ P+ A VF Sbjct: 587 YSKTSQSVSGEEIDAMDVQQLSQIVPKVA----------------------------VFY 618 Query: 682 RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 741 R SP+ K+ I++ Q+ G++VA+TGDGVND+ ALK ADIGVAMG G+DV K+AADMIL+ Sbjct: 619 RASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILV 678 Query: 742 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCID 801 DD+F +I++ +EEG+ I++N+K + + L+++I +T L + N P PL + IL I+ Sbjct: 679 DDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWIN 738 Query: 802 LGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFV 861 + D PA SL E + D++++ PRN + L ++ + I I G F ++ Sbjct: 739 IIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWR 796 Query: 862 ILAENGFLP 870 L +N P Sbjct: 797 ELRDNVITP 805 >gi|48762689 calcium-transporting ATPase 2C1 isoform 1d [Homo sapiens] Length = 949 Score = 376 bits (965), Expect = e-104 Identities = 269/849 (31%), Positives = 422/849 (49%), Gaps = 84/849 (9%) Query: 35 KMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILL 94 ++ V EV D GL + A G N P W K+ Q +LL Sbjct: 28 ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87 Query: 95 WIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNM 154 A++ L + DD + I +A ++++T F QE +S K +E + Sbjct: 88 LASAVISVLMHQF-----DDA------VSITVAILIVVTVAF--VQEYRSEKSLEELSKL 134 Query: 155 VPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEP 214 VP + +REG+ A ++V GD V + GDRVPADLR+ A +D SSLTGE+ P Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194 Query: 215 QTR----SPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVG 270 ++ P T+ + NI F T G A+GVV+ TG+ + G + + E Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254 Query: 271 KTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVANVPEGLLATV 330 KTP+ ++ + ++ + + ++ +LG LE + + VA +PEGL V Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314 Query: 331 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEA 390 TV L L RM +K +VK L VETLG + ICSDKTGTLT+N MTV H++ + +H Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374 Query: 391 DTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFK----GGQDNIPVLKRD-VAGDASESA 445 T G +++ V + G N AV + G N V++ + + G +E A Sbjct: 375 VT-----GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGA 429 Query: 446 LLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQL--SIHETEDPNDNRYLLVMKGAPER 503 L+ + + G L ++ +K AE PF+S K+ +H T+ D + MKGA E+ Sbjct: 430 LI-ALAMKMGLDGLQQDYIRK-AEYPFSSEQKWMAVKCVHRTQQ--DRPEICFMKGAYEQ 485 Query: 504 ILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDC 563 ++ C+T +G+ L ++ ++ +Q +G G RVL PE Sbjct: 486 VIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASG--PE----------- 532 Query: 564 DDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 623 L F+GL+ +IDPPR V +AV ++G+ + M+TGD TA AIA +G+ Sbjct: 533 ------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586 Query: 624 ISEGNETV--EDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFA 681 S+ +++V E+I A +SQ+ P+ A VF Sbjct: 587 YSKTSQSVSGEEIDAMDVQQLSQIVPKVA----------------------------VFY 618 Query: 682 RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 741 R SP+ K+ I++ Q+ G++VA+TGDGVND+ ALK ADIGVAMG G+DV K+AADMIL+ Sbjct: 619 RASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILV 678 Query: 742 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCID 801 DD+F +I++ +EEG+ I++N+K + + L+++I +T L + N P PL + IL I+ Sbjct: 679 DDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWIN 738 Query: 802 LGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFV 861 + D PA SL E + D++++ PRN + L ++ + I I G F ++ Sbjct: 739 IIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWR 796 Query: 862 ILAENGFLP 870 L +N P Sbjct: 797 ELRDNVITP 805 >gi|48762687 calcium-transporting ATPase 2C1 isoform 1c [Homo sapiens] Length = 888 Score = 376 bits (965), Expect = e-104 Identities = 269/849 (31%), Positives = 422/849 (49%), Gaps = 84/849 (9%) Query: 35 KMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILL 94 ++ V EV D GL + A G N P W K+ Q +LL Sbjct: 28 ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87 Query: 95 WIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNM 154 A++ L + DD + I +A ++++T F QE +S K +E + Sbjct: 88 LASAVISVLMHQF-----DDA------VSITVAILIVVTVAF--VQEYRSEKSLEELSKL 134 Query: 155 VPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEP 214 VP + +REG+ A ++V GD V + GDRVPADLR+ A +D SSLTGE+ P Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194 Query: 215 QTR----SPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVG 270 ++ P T+ + NI F T G A+GVV+ TG+ + G + + E Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254 Query: 271 KTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVANVPEGLLATV 330 KTP+ ++ + ++ + + ++ +LG LE + + VA +PEGL V Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314 Query: 331 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEA 390 TV L L RM +K +VK L VETLG + ICSDKTGTLT+N MTV H++ + +H Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374 Query: 391 DTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFK----GGQDNIPVLKRD-VAGDASESA 445 T G +++ V + G N AV + G N V++ + + G +E A Sbjct: 375 VT-----GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGA 429 Query: 446 LLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQL--SIHETEDPNDNRYLLVMKGAPER 503 L+ + + G L ++ +K AE PF+S K+ +H T+ D + MKGA E+ Sbjct: 430 LI-ALAMKMGLDGLQQDYIRK-AEYPFSSEQKWMAVKCVHRTQQ--DRPEICFMKGAYEQ 485 Query: 504 ILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDC 563 ++ C+T +G+ L ++ ++ +Q +G G RVL PE Sbjct: 486 VIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASG--PE----------- 532 Query: 564 DDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 623 L F+GL+ +IDPPR V +AV ++G+ + M+TGD TA AIA +G+ Sbjct: 533 ------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586 Query: 624 ISEGNETV--EDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFA 681 S+ +++V E+I A +SQ+ P+ A VF Sbjct: 587 YSKTSQSVSGEEIDAMDVQQLSQIVPKVA----------------------------VFY 618 Query: 682 RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 741 R SP+ K+ I++ Q+ G++VA+TGDGVND+ ALK ADIGVAMG G+DV K+AADMIL+ Sbjct: 619 RASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILV 678 Query: 742 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCID 801 DD+F +I++ +EEG+ I++N+K + + L+++I +T L + N P PL + IL I+ Sbjct: 679 DDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWIN 738 Query: 802 LGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFV 861 + D PA SL E + D++++ PRN + L ++ + I I G F ++ Sbjct: 739 IIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWR 796 Query: 862 ILAENGFLP 870 L +N P Sbjct: 797 ELRDNVITP 805 >gi|48762685 calcium-transporting ATPase 2C1 isoform 1a [Homo sapiens] Length = 919 Score = 376 bits (965), Expect = e-104 Identities = 269/849 (31%), Positives = 422/849 (49%), Gaps = 84/849 (9%) Query: 35 KMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSILL 94 ++ V EV D GL + A G N P W K+ Q +LL Sbjct: 28 ELPVSEVASILQADLQNGLNKCEVSHRRAFHGWNEFDISEDEPLWKKYISQFKNPLIMLL 87 Query: 95 WIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKNM 154 A++ L + DD + I +A ++++T F QE +S K +E + Sbjct: 88 LASAVISVLMHQF-----DDA------VSITVAILIVVTVAF--VQEYRSEKSLEELSKL 134 Query: 155 VPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEP 214 VP + +REG+ A ++V GD V + GDRVPADLR+ A +D SSLTGE+ P Sbjct: 135 VPPECHCVREGKLEHTLARDLVPGDTVCLSVGDRVPADLRLFEAVDLSIDESSLTGETTP 194 Query: 215 QTR----SPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVG 270 ++ P T+ + NI F T G A+GVV+ TG+ + G + + E Sbjct: 195 CSKVTAPQPAATNGDLASRSNIAFMGTLVRCGKAKGVVIGTGENSEFGEVFKMMQAEEAP 254 Query: 271 KTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLEAVIFLIGIIVANVPEGLLATV 330 KTP+ ++ + ++ + + ++ +LG LE + + VA +PEGL V Sbjct: 255 KTPLQKSMDLLGKQLSFYSFGIIGIIMLVGWLLGKDILEMFTISVSLAVAAIPEGLPIVV 314 Query: 331 TVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEA 390 TV L L RM +K +VK L VETLG + ICSDKTGTLT+N MTV H++ + +H Sbjct: 315 TVTLALGVMRMVKKRAIVKKLPIVETLGCCNVICSDKTGTLTKNEMTVTHIFTSDGLHAE 374 Query: 391 DTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFK----GGQDNIPVLKRD-VAGDASESA 445 T G +++ V + G N AV + G N V++ + + G +E A Sbjct: 375 VT-----GVGYNQFGEVIVDGDVVHGFYNPAVSRIVEAGCVCNDAVIRNNTLMGKPTEGA 429 Query: 446 LLKCIELSSGSVKLMRERNKKVAEIPFNSTNKYQL--SIHETEDPNDNRYLLVMKGAPER 503 L+ + + G L ++ +K AE PF+S K+ +H T+ D + MKGA E+ Sbjct: 430 LI-ALAMKMGLDGLQQDYIRK-AEYPFSSEQKWMAVKCVHRTQQ--DRPEICFMKGAYEQ 485 Query: 504 ILDRCSTILLQGKEQPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDC 563 ++ C+T +G+ L ++ ++ +Q +G G RVL PE Sbjct: 486 VIKYCTTYQSKGQTLTLTQQQRDVYQQEKARMGSAGLRVLALASG--PE----------- 532 Query: 564 DDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGI 623 L F+GL+ +IDPPR V +AV ++G+ + M+TGD TA AIA +G+ Sbjct: 533 ------LGQLTFLGLVGIIDPPRTGVKEAVTTLIASGVSIKMITGDSQETAVAIASRLGL 586 Query: 624 ISEGNETV--EDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFA 681 S+ +++V E+I A +SQ+ P+ A VF Sbjct: 587 YSKTSQSVSGEEIDAMDVQQLSQIVPKVA----------------------------VFY 618 Query: 682 RTSPQQKLIIVEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILL 741 R SP+ K+ I++ Q+ G++VA+TGDGVND+ ALK ADIGVAMG G+DV K+AADMIL+ Sbjct: 619 RASPRHKMKIIKSLQKNGSVVAMTGDGVNDAVALKAADIGVAMGQTGTDVCKEAADMILV 678 Query: 742 DDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCID 801 DD+F +I++ +EEG+ I++N+K + + L+++I +T L + N P PL + IL I+ Sbjct: 679 DDDFQTIMSAIEEGKGIYNNIKNFVRFQLSTSIAALTLISLATLMNFPNPLNAMQILWIN 738 Query: 802 LGTDMVPAISLAYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFV 861 + D PA SL E + D++++ PRN + L ++ + I I G F ++ Sbjct: 739 IIMDGPPAQSLGVEPVDKDVIRKPPRNWKDSILTKNLILKILVSSI--IIVCGTLFVFWR 796 Query: 862 ILAENGFLP 870 L +N P Sbjct: 797 ELRDNVITP 805 >gi|28373103 ATPase, Ca++ transporting, ubiquitous isoform a [Homo sapiens] Length = 999 Score = 374 bits (960), Expect = e-103 Identities = 270/857 (31%), Positives = 425/857 (49%), Gaps = 96/857 (11%) Query: 34 HKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 93 H + +V R ++ GL+ ++ R GPN L W Q + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 94 LWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKN 153 L + A++ F+ + G E + +V+ +++ +QE + +E+ K Sbjct: 65 LLLAALVSFVLAWFEEGEETTTA---FVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 154 MVPQQALVIREGEK--MQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGC--KVDNSSLT 209 P+ VIR K ++ A ++V GD+VE+ GD+VPADLR+I +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 210 GESEPQTRSPDCTHDNPL---ETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASG 266 GES T+ + D + +N+ F TN G A GV VATG T +G+I + + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 267 LEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSL------ILGYTWLEAVIFL----IG 316 +E +TP+ +++ F + ++ + V+ +++++ G +WL ++ + Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 317 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 376 + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 377 TVAHMWFDNQIHEADTTE------DQSGTSFDKSSHT--------------WVALSHIAG 416 +V M+ + EAD SGT++ V L+ I Sbjct: 362 SVCRMFV---VAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICA 418 Query: 417 LCNRAVFKGGQDNIPVLKRDVAGDASESAL----------------LKCIELSSGSVKLM 460 LCN + + K G+A+E+AL L +E + ++ Sbjct: 419 LCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVI 475 Query: 461 RERNKKVAEIPFNSTNKYQLSIHETED---PNDNRYLLVMKGAPERILDRCSTILLQGKE 517 ++ +K + F+ K +S++ T P + +KGAPE +++RCS++ + + Sbjct: 476 KQLMRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRT 534 Query: 518 QPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDD----VNFTTDNL 573 PL +E A + G G L C + P+ + DD V + TD L Sbjct: 535 APLTPTSREQIL-AKIRDWGSGSDTLR-CLALATRDAPPRKEDMELDDCSKFVQYETD-L 591 Query: 574 CFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVED 633 FVG + M+DPPR V + +C AGI+V+M+TGD+ TA AI + +GI + ED Sbjct: 592 TFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TED 647 Query: 634 IAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVE 693 +A + G + D + EQ + + T FAR P K IVE Sbjct: 648 VAGK----------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVE 689 Query: 694 GCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVE 753 Q I A+TGDGVND+PALKKA+IG+AMG +G+ V+K AA+M+L DDNFASIV VE Sbjct: 690 NLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVE 748 Query: 754 EGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLA 813 EGR I+ N+K+ I Y ++SN+ E+ L + +P L + +L ++L TD +PA +L Sbjct: 749 EGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALG 808 Query: 814 YEAAESDIMKRQPRNPR 830 + + DIM++ PR+PR Sbjct: 809 FNPPDLDIMEKLPRSPR 825 >gi|28373115 ATPase, Ca++ transporting, ubiquitous isoform c [Homo sapiens] Length = 1029 Score = 374 bits (960), Expect = e-103 Identities = 270/857 (31%), Positives = 425/857 (49%), Gaps = 96/857 (11%) Query: 34 HKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 93 H + +V R ++ GL+ ++ R GPN L W Q + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 94 LWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKN 153 L + A++ F+ + G E + +V+ +++ +QE + +E+ K Sbjct: 65 LLLAALVSFVLAWFEEGEETTTA---FVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 154 MVPQQALVIREGEK--MQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGC--KVDNSSLT 209 P+ VIR K ++ A ++V GD+VE+ GD+VPADLR+I +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 210 GESEPQTRSPDCTHDNPL---ETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASG 266 GES T+ + D + +N+ F TN G A GV VATG T +G+I + + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 267 LEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSL------ILGYTWLEAVIFL----IG 316 +E +TP+ +++ F + ++ + V+ +++++ G +WL ++ + Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 317 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 376 + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 377 TVAHMWFDNQIHEADTTE------DQSGTSFDKSSHT--------------WVALSHIAG 416 +V M+ + EAD SGT++ V L+ I Sbjct: 362 SVCRMFV---VAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICA 418 Query: 417 LCNRAVFKGGQDNIPVLKRDVAGDASESAL----------------LKCIELSSGSVKLM 460 LCN + + K G+A+E+AL L +E + ++ Sbjct: 419 LCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVI 475 Query: 461 RERNKKVAEIPFNSTNKYQLSIHETED---PNDNRYLLVMKGAPERILDRCSTILLQGKE 517 ++ +K + F+ K +S++ T P + +KGAPE +++RCS++ + + Sbjct: 476 KQLMRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRT 534 Query: 518 QPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDD----VNFTTDNL 573 PL +E A + G G L C + P+ + DD V + TD L Sbjct: 535 APLTPTSREQIL-AKIRDWGSGSDTLR-CLALATRDAPPRKEDMELDDCSKFVQYETD-L 591 Query: 574 CFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVED 633 FVG + M+DPPR V + +C AGI+V+M+TGD+ TA AI + +GI + ED Sbjct: 592 TFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TED 647 Query: 634 IAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVE 693 +A + G + D + EQ + + T FAR P K IVE Sbjct: 648 VAGK----------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVE 689 Query: 694 GCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVE 753 Q I A+TGDGVND+PALKKA+IG+AMG +G+ V+K AA+M+L DDNFASIV VE Sbjct: 690 NLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVE 748 Query: 754 EGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLA 813 EGR I+ N+K+ I Y ++SN+ E+ L + +P L + +L ++L TD +PA +L Sbjct: 749 EGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALG 808 Query: 814 YEAAESDIMKRQPRNPR 830 + + DIM++ PR+PR Sbjct: 809 FNPPDLDIMEKLPRSPR 825 >gi|28373113 ATPase, Ca++ transporting, ubiquitous isoform f [Homo sapiens] Length = 998 Score = 374 bits (960), Expect = e-103 Identities = 270/857 (31%), Positives = 425/857 (49%), Gaps = 96/857 (11%) Query: 34 HKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 93 H + +V R ++ GL+ ++ R GPN L W Q + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 94 LWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKN 153 L + A++ F+ + G E + +V+ +++ +QE + +E+ K Sbjct: 65 LLLAALVSFVLAWFEEGEETTTA---FVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 154 MVPQQALVIREGEK--MQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGC--KVDNSSLT 209 P+ VIR K ++ A ++V GD+VE+ GD+VPADLR+I +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 210 GESEPQTRSPDCTHDNPL---ETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASG 266 GES T+ + D + +N+ F TN G A GV VATG T +G+I + + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 267 LEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSL------ILGYTWLEAVIFL----IG 316 +E +TP+ +++ F + ++ + V+ +++++ G +WL ++ + Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 317 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 376 + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 377 TVAHMWFDNQIHEADTTE------DQSGTSFDKSSHT--------------WVALSHIAG 416 +V M+ + EAD SGT++ V L+ I Sbjct: 362 SVCRMFV---VAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICA 418 Query: 417 LCNRAVFKGGQDNIPVLKRDVAGDASESAL----------------LKCIELSSGSVKLM 460 LCN + + K G+A+E+AL L +E + ++ Sbjct: 419 LCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVI 475 Query: 461 RERNKKVAEIPFNSTNKYQLSIHETED---PNDNRYLLVMKGAPERILDRCSTILLQGKE 517 ++ +K + F+ K +S++ T P + +KGAPE +++RCS++ + + Sbjct: 476 KQLMRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRT 534 Query: 518 QPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDD----VNFTTDNL 573 PL +E A + G G L C + P+ + DD V + TD L Sbjct: 535 APLTPTSREQIL-AKIRDWGSGSDTLR-CLALATRDAPPRKEDMELDDCSKFVQYETD-L 591 Query: 574 CFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVED 633 FVG + M+DPPR V + +C AGI+V+M+TGD+ TA AI + +GI + ED Sbjct: 592 TFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TED 647 Query: 634 IAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVE 693 +A + G + D + EQ + + T FAR P K IVE Sbjct: 648 VAGK----------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVE 689 Query: 694 GCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVE 753 Q I A+TGDGVND+PALKKA+IG+AMG +G+ V+K AA+M+L DDNFASIV VE Sbjct: 690 NLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVE 748 Query: 754 EGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLA 813 EGR I+ N+K+ I Y ++SN+ E+ L + +P L + +L ++L TD +PA +L Sbjct: 749 EGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALG 808 Query: 814 YEAAESDIMKRQPRNPR 830 + + DIM++ PR+PR Sbjct: 809 FNPPDLDIMEKLPRSPR 825 >gi|28373111 ATPase, Ca++ transporting, ubiquitous isoform c [Homo sapiens] Length = 1029 Score = 374 bits (960), Expect = e-103 Identities = 270/857 (31%), Positives = 425/857 (49%), Gaps = 96/857 (11%) Query: 34 HKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 93 H + +V R ++ GL+ ++ R GPN L W Q + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 94 LWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKN 153 L + A++ F+ + G E + +V+ +++ +QE + +E+ K Sbjct: 65 LLLAALVSFVLAWFEEGEETTTA---FVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 154 MVPQQALVIREGEK--MQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGC--KVDNSSLT 209 P+ VIR K ++ A ++V GD+VE+ GD+VPADLR+I +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 210 GESEPQTRSPDCTHDNPL---ETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASG 266 GES T+ + D + +N+ F TN G A GV VATG T +G+I + + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 267 LEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSL------ILGYTWLEAVIFL----IG 316 +E +TP+ +++ F + ++ + V+ +++++ G +WL ++ + Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 317 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 376 + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 377 TVAHMWFDNQIHEADTTE------DQSGTSFDKSSHT--------------WVALSHIAG 416 +V M+ + EAD SGT++ V L+ I Sbjct: 362 SVCRMFV---VAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICA 418 Query: 417 LCNRAVFKGGQDNIPVLKRDVAGDASESAL----------------LKCIELSSGSVKLM 460 LCN + + K G+A+E+AL L +E + ++ Sbjct: 419 LCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVI 475 Query: 461 RERNKKVAEIPFNSTNKYQLSIHETED---PNDNRYLLVMKGAPERILDRCSTILLQGKE 517 ++ +K + F+ K +S++ T P + +KGAPE +++RCS++ + + Sbjct: 476 KQLMRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRT 534 Query: 518 QPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDD----VNFTTDNL 573 PL +E A + G G L C + P+ + DD V + TD L Sbjct: 535 APLTPTSREQIL-AKIRDWGSGSDTLR-CLALATRDAPPRKEDMELDDCSKFVQYETD-L 591 Query: 574 CFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVED 633 FVG + M+DPPR V + +C AGI+V+M+TGD+ TA AI + +GI + ED Sbjct: 592 TFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TED 647 Query: 634 IAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVE 693 +A + G + D + EQ + + T FAR P K IVE Sbjct: 648 VAGK----------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVE 689 Query: 694 GCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVE 753 Q I A+TGDGVND+PALKKA+IG+AMG +G+ V+K AA+M+L DDNFASIV VE Sbjct: 690 NLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVE 748 Query: 754 EGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLA 813 EGR I+ N+K+ I Y ++SN+ E+ L + +P L + +L ++L TD +PA +L Sbjct: 749 EGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALG 808 Query: 814 YEAAESDIMKRQPRNPR 830 + + DIM++ PR+PR Sbjct: 809 FNPPDLDIMEKLPRSPR 825 >gi|28373109 ATPase, Ca++ transporting, ubiquitous isoform b [Homo sapiens] Length = 1043 Score = 374 bits (960), Expect = e-103 Identities = 270/857 (31%), Positives = 425/857 (49%), Gaps = 96/857 (11%) Query: 34 HKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 93 H + +V R ++ GL+ ++ R GPN L W Q + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 94 LWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKN 153 L + A++ F+ + G E + +V+ +++ +QE + +E+ K Sbjct: 65 LLLAALVSFVLAWFEEGEETTTA---FVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 154 MVPQQALVIREGEK--MQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGC--KVDNSSLT 209 P+ VIR K ++ A ++V GD+VE+ GD+VPADLR+I +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 210 GESEPQTRSPDCTHDNPL---ETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASG 266 GES T+ + D + +N+ F TN G A GV VATG T +G+I + + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 267 LEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSL------ILGYTWLEAVIFL----IG 316 +E +TP+ +++ F + ++ + V+ +++++ G +WL ++ + Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 317 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 376 + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 377 TVAHMWFDNQIHEADTTE------DQSGTSFDKSSHT--------------WVALSHIAG 416 +V M+ + EAD SGT++ V L+ I Sbjct: 362 SVCRMFV---VAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICA 418 Query: 417 LCNRAVFKGGQDNIPVLKRDVAGDASESAL----------------LKCIELSSGSVKLM 460 LCN + + K G+A+E+AL L +E + ++ Sbjct: 419 LCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVI 475 Query: 461 RERNKKVAEIPFNSTNKYQLSIHETED---PNDNRYLLVMKGAPERILDRCSTILLQGKE 517 ++ +K + F+ K +S++ T P + +KGAPE +++RCS++ + + Sbjct: 476 KQLMRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRT 534 Query: 518 QPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDD----VNFTTDNL 573 PL +E A + G G L C + P+ + DD V + TD L Sbjct: 535 APLTPTSREQIL-AKIRDWGSGSDTLR-CLALATRDAPPRKEDMELDDCSKFVQYETD-L 591 Query: 574 CFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVED 633 FVG + M+DPPR V + +C AGI+V+M+TGD+ TA AI + +GI + ED Sbjct: 592 TFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TED 647 Query: 634 IAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVE 693 +A + G + D + EQ + + T FAR P K IVE Sbjct: 648 VAGK----------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVE 689 Query: 694 GCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVE 753 Q I A+TGDGVND+PALKKA+IG+AMG +G+ V+K AA+M+L DDNFASIV VE Sbjct: 690 NLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVE 748 Query: 754 EGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLA 813 EGR I+ N+K+ I Y ++SN+ E+ L + +P L + +L ++L TD +PA +L Sbjct: 749 EGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALG 808 Query: 814 YEAAESDIMKRQPRNPR 830 + + DIM++ PR+PR Sbjct: 809 FNPPDLDIMEKLPRSPR 825 >gi|28373107 ATPase, Ca++ transporting, ubiquitous isoform d [Homo sapiens] Length = 1044 Score = 374 bits (960), Expect = e-103 Identities = 270/857 (31%), Positives = 425/857 (49%), Gaps = 96/857 (11%) Query: 34 HKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 93 H + +V R ++ GL+ ++ R GPN L W Q + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 94 LWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKN 153 L + A++ F+ + G E + +V+ +++ +QE + +E+ K Sbjct: 65 LLLAALVSFVLAWFEEGEETTTA---FVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 154 MVPQQALVIREGEK--MQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGC--KVDNSSLT 209 P+ VIR K ++ A ++V GD+VE+ GD+VPADLR+I +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 210 GESEPQTRSPDCTHDNPL---ETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASG 266 GES T+ + D + +N+ F TN G A GV VATG T +G+I + + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 267 LEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSL------ILGYTWLEAVIFL----IG 316 +E +TP+ +++ F + ++ + V+ +++++ G +WL ++ + Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 317 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 376 + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 377 TVAHMWFDNQIHEADTTE------DQSGTSFDKSSHT--------------WVALSHIAG 416 +V M+ + EAD SGT++ V L+ I Sbjct: 362 SVCRMFV---VAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICA 418 Query: 417 LCNRAVFKGGQDNIPVLKRDVAGDASESAL----------------LKCIELSSGSVKLM 460 LCN + + K G+A+E+AL L +E + ++ Sbjct: 419 LCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVI 475 Query: 461 RERNKKVAEIPFNSTNKYQLSIHETED---PNDNRYLLVMKGAPERILDRCSTILLQGKE 517 ++ +K + F+ K +S++ T P + +KGAPE +++RCS++ + + Sbjct: 476 KQLMRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRT 534 Query: 518 QPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDD----VNFTTDNL 573 PL +E A + G G L C + P+ + DD V + TD L Sbjct: 535 APLTPTSREQIL-AKIRDWGSGSDTLR-CLALATRDAPPRKEDMELDDCSKFVQYETD-L 591 Query: 574 CFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVED 633 FVG + M+DPPR V + +C AGI+V+M+TGD+ TA AI + +GI + ED Sbjct: 592 TFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TED 647 Query: 634 IAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVE 693 +A + G + D + EQ + + T FAR P K IVE Sbjct: 648 VAGK----------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVE 689 Query: 694 GCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVE 753 Q I A+TGDGVND+PALKKA+IG+AMG +G+ V+K AA+M+L DDNFASIV VE Sbjct: 690 NLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVE 748 Query: 754 EGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLA 813 EGR I+ N+K+ I Y ++SN+ E+ L + +P L + +L ++L TD +PA +L Sbjct: 749 EGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALG 808 Query: 814 YEAAESDIMKRQPRNPR 830 + + DIM++ PR+PR Sbjct: 809 FNPPDLDIMEKLPRSPR 825 >gi|28373105 ATPase, Ca++ transporting, ubiquitous isoform e [Homo sapiens] Length = 1052 Score = 374 bits (960), Expect = e-103 Identities = 270/857 (31%), Positives = 425/857 (49%), Gaps = 96/857 (11%) Query: 34 HKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 93 H + +V R ++ GL+ ++ R GPN L W Q + Sbjct: 5 HLLPAADVLRHFSVTAEGGLSPAQVTGARERYGPNELPSEEGKSLWELVLEQFEDLLVRI 64 Query: 94 LWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKN 153 L + A++ F+ + G E + +V+ +++ +QE + +E+ K Sbjct: 65 LLLAALVSFVLAWFEEGEETTTA---FVEPLVIMLILVANAIVGVWQERNAESAIEALKE 121 Query: 154 MVPQQALVIREGEK--MQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGC--KVDNSSLT 209 P+ VIR K ++ A ++V GD+VE+ GD+VPADLR+I +VD S LT Sbjct: 122 YEPEMGKVIRSDRKGVQRIRARDIVPGDIVEVAVGDKVPADLRLIEIKSTTLRVDQSILT 181 Query: 210 GESEPQTRSPDCTHDNPL---ETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASG 266 GES T+ + D + +N+ F TN G A GV VATG T +G+I + + Sbjct: 182 GESVSVTKHTEAIPDPRAVNQDKKNMLFSGTNITSGKAVGVAVATGLHTELGKIRSQMAA 241 Query: 267 LEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSL------ILGYTWLEAVIFL----IG 316 +E +TP+ +++ F + ++ + V+ +++++ G +WL ++ + Sbjct: 242 VEPERTPLQRKLDEFGRQLSHAISVICVAVWVINIGHFADPAHGGSWLRGAVYYFKIAVA 301 Query: 317 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 376 + VA +PEGL A +T CL L +RMARKN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMARKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 377 TVAHMWFDNQIHEADTTE------DQSGTSFDKSSHT--------------WVALSHIAG 416 +V M+ + EAD SGT++ V L+ I Sbjct: 362 SVCRMFV---VAEADAGSCLLHEFTISGTTYTPEGEVRQGDQPVRCGQFDGLVELATICA 418 Query: 417 LCNRAVFKGGQDNIPVLKRDVAGDASESAL----------------LKCIELSSGSVKLM 460 LCN + + K G+A+E+AL L +E + ++ Sbjct: 419 LCNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTDLQALSRVERAGACNTVI 475 Query: 461 RERNKKVAEIPFNSTNKYQLSIHETED---PNDNRYLLVMKGAPERILDRCSTILLQGKE 517 ++ +K + F+ K +S++ T P + +KGAPE +++RCS++ + + Sbjct: 476 KQLMRKEFTLEFSRDRK-SMSVYCTPTRPHPTGQGSKMFVKGAPESVIERCSSVRVGSRT 534 Query: 518 QPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDD----VNFTTDNL 573 PL +E A + G G L C + P+ + DD V + TD L Sbjct: 535 APLTPTSREQIL-AKIRDWGSGSDTLR-CLALATRDAPPRKEDMELDDCSKFVQYETD-L 591 Query: 574 CFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVED 633 FVG + M+DPPR V + +C AGI+V+M+TGD+ TA AI + +GI + ED Sbjct: 592 TFVGCVGMLDPPRPEVAACITRCYQAGIRVVMITGDNKGTAVAICRRLGIFGD----TED 647 Query: 634 IAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVE 693 +A + G + D + EQ + + T FAR P K IVE Sbjct: 648 VAGK----------------AYTGREFDDLSPEQQRQACR--TARCFARVEPAHKSRIVE 689 Query: 694 GCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVE 753 Q I A+TGDGVND+PALKKA+IG+AMG +G+ V+K AA+M+L DDNFASIV VE Sbjct: 690 NLQSFNEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKSAAEMVLSDDNFASIVAAVE 748 Query: 754 EGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLA 813 EGR I+ N+K+ I Y ++SN+ E+ L + +P L + +L ++L TD +PA +L Sbjct: 749 EGRAIYSNMKQFIRYLISSNVGEVVCIFLTAILGLPEALIPVQLLWVNLVTDGLPATALG 808 Query: 814 YEAAESDIMKRQPRNPR 830 + + DIM++ PR+PR Sbjct: 809 FNPPDLDIMEKLPRSPR 825 >gi|4502285 ATPase, Ca++ transporting, slow twitch 2 isoform 2 [Homo sapiens] Length = 997 Score = 363 bits (932), Expect = e-100 Identities = 268/859 (31%), Positives = 434/859 (50%), Gaps = 101/859 (11%) Query: 34 HKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSI- 92 H +VEEV + + GL+ + +++ R G N L P ++ + F + Sbjct: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63 Query: 93 LLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFK 152 +L + A + F+ + G E + + V+ +++ +QE + +E+ K Sbjct: 64 ILLLAACISFVLAWFEEGEETITAFVEPF---VILLILVANAIVGVWQERNAENAIEALK 120 Query: 153 NMVPQQALVIREGEK--MQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGC--KVDNSSL 208 P+ V R+ K ++ A+++V GD+VEI GD+VPAD+R+ S +VD S L Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 Query: 209 TGESEPQTRSPDCTHDNPL---ETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLAS 265 TGES + D D + +N+ F TN G A GVVVATG T +G+I Sbjct: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 Query: 266 GLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSL------ILGYTWLEAVIFL----I 315 E +TP+ +++ F + ++ V + ++ +I+++ + G +W+ I+ + Sbjct: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 Query: 316 GIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNR 375 + VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 376 MTVAHMWFDNQIHEADTTEDQ----SGTSF---------DK--SSHTW---VALSHIAGL 417 M+V M+ +++ E DT +G+++ DK + H + V L+ I L Sbjct: 361 MSVCRMFILDRV-EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICAL 419 Query: 418 CNRAVFKGGQDNIPVLKRDVAGDASESAL----------------LKCIELSSGSVKLMR 461 CN + + K G+A+E+AL L IE ++ +++ Sbjct: 420 CNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIK 476 Query: 462 ERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYL--LVMKGAPERILDRCSTILLQGKEQP 519 + KK + F+ K +S++ T + + + +KGAPE ++DRC+ I + + P Sbjct: 477 QLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVP 535 Query: 520 LDEEMKEAFQNAYLELGGLGE--RVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVG 577 + +K+ + E G + R L + P + + + + T NL FVG Sbjct: 536 MTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYET-NLTFVG 594 Query: 578 LMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAAR 637 + M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + ED+ + Sbjct: 595 CVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQD----EDVTS- 649 Query: 638 LNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIV------FARTSPQQKLII 691 K FT + DE+ + FAR P K I Sbjct: 650 -----------------------KAFTGREFDELNPSAQRDACLNARCFARVEPSHKSKI 686 Query: 692 VEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTG 751 VE Q I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV Sbjct: 687 VEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAA 745 Query: 752 VEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAIS 811 VEEGR I++N+K+ I Y ++SN+ E+ L P L + +L ++L TD +PA + Sbjct: 746 VEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATA 805 Query: 812 LAYEAAESDIMKRQPRNPR 830 L + + DIM + PRNP+ Sbjct: 806 LGFNPPDLDIMNKPPRNPK 824 >gi|24638454 ATPase, Ca++ transporting, slow twitch 2 isoform 1 [Homo sapiens] Length = 1042 Score = 363 bits (932), Expect = e-100 Identities = 268/859 (31%), Positives = 434/859 (50%), Gaps = 101/859 (11%) Query: 34 HKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSI- 92 H +VEEV + + GL+ + +++ R G N L P ++ + F + Sbjct: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63 Query: 93 LLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFK 152 +L + A + F+ + G E + + V+ +++ +QE + +E+ K Sbjct: 64 ILLLAACISFVLAWFEEGEETITAFVEPF---VILLILVANAIVGVWQERNAENAIEALK 120 Query: 153 NMVPQQALVIREGEK--MQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGC--KVDNSSL 208 P+ V R+ K ++ A+++V GD+VEI GD+VPAD+R+ S +VD S L Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAVGDKVPADIRLTSIKSTTLRVDQSIL 180 Query: 209 TGESEPQTRSPDCTHDNPL---ETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLAS 265 TGES + D D + +N+ F TN G A GVVVATG T +G+I Sbjct: 181 TGESVSVIKHTDPVPDPRAVNQDKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMV 240 Query: 266 GLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSL------ILGYTWLEAVIFL----I 315 E +TP+ +++ F + ++ V + ++ +I+++ + G +W+ I+ + Sbjct: 241 ATEQERTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAV 300 Query: 316 GIIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNR 375 + VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+ Sbjct: 301 ALAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQ 360 Query: 376 MTVAHMWFDNQIHEADTTEDQ----SGTSF---------DK--SSHTW---VALSHIAGL 417 M+V M+ +++ E DT +G+++ DK + H + V L+ I L Sbjct: 361 MSVCRMFILDRV-EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICAL 419 Query: 418 CNRAVFKGGQDNIPVLKRDVAGDASESAL----------------LKCIELSSGSVKLMR 461 CN + + K G+A+E+AL L IE ++ +++ Sbjct: 420 CNDSALDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIK 476 Query: 462 ERNKKVAEIPFNSTNKYQLSIHETEDPNDNRYL--LVMKGAPERILDRCSTILLQGKEQP 519 + KK + F+ K +S++ T + + + +KGAPE ++DRC+ I + + P Sbjct: 477 QLMKKEFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVP 535 Query: 520 LDEEMKEAFQNAYLELGGLGE--RVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVG 577 + +K+ + E G + R L + P + + + + T NL FVG Sbjct: 536 MTSGVKQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYET-NLTFVG 594 Query: 578 LMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAAR 637 + M+DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + ED+ + Sbjct: 595 CVGMLDPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQD----EDVTS- 649 Query: 638 LNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIV------FARTSPQQKLII 691 K FT + DE+ + FAR P K I Sbjct: 650 -----------------------KAFTGREFDELNPSAQRDACLNARCFARVEPSHKSKI 686 Query: 692 VEGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTG 751 VE Q I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV Sbjct: 687 VEFLQSFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAA 745 Query: 752 VEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAIS 811 VEEGR I++N+K+ I Y ++SN+ E+ L P L + +L ++L TD +PA + Sbjct: 746 VEEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATA 805 Query: 812 LAYEAAESDIMKRQPRNPR 830 L + + DIM + PRNP+ Sbjct: 806 LGFNPPDLDIMNKPPRNPK 824 >gi|10835220 ATPase, Ca++ transporting, fast twitch 1 isoform b [Homo sapiens] Length = 994 Score = 358 bits (918), Expect = 2e-98 Identities = 297/1042 (28%), Positives = 482/1042 (46%), Gaps = 132/1042 (12%) Query: 34 HKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 93 H + EE + GLT + + L + G N L W Q + Sbjct: 5 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64 Query: 94 LWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKN 153 L + A + F+ + G E + + V+ ++I +QE + +E+ K Sbjct: 65 LLLAACISFVLAWFEEGEETITAFVEPF---VILLILIANAIVGVWQERNAENAIEALKE 121 Query: 154 MVPQQALVIREGEK--MQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGC--KVDNSSLT 209 P+ V R K ++ A ++V GD+VE+ GD+VPAD+RI++ +VD S LT Sbjct: 122 YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 181 Query: 210 GESEPQTRSPDCTHDNPL---ETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASG 266 GES + + D + +N+ F TN G A G+V TG T +G+I + Sbjct: 182 GESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAA 241 Query: 267 LEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSL------ILGYTWLEAVIFL----IG 316 E KTP+ +++ F + ++ V + V+ +++++ + G +W I+ + Sbjct: 242 TEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVA 301 Query: 317 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 376 + VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 377 TVAHMWFDNQIHEADTTEDQ---SGTSFDKSSHTW--------------VALSHIAGLCN 419 +V M+ +++ ++ +G+++ V L+ I LCN Sbjct: 362 SVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCN 421 Query: 420 RAVFKGGQDNIPVLKRDVAGDASESAL----------------LKCIELSSGSVKLMRER 463 + + K G+A+E+AL L +E ++ ++R+ Sbjct: 422 DSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQL 478 Query: 464 NKKVAEIPFNSTNKYQLSIHETEDPNDNRYL---LVMKGAPERILDRCSTILLQGKEQPL 520 KK + F+ K +S++ + + + + +KGAPE ++DRC+ + + PL Sbjct: 479 MKKEFTLEFSRDRK-SMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPL 537 Query: 521 DEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDD----VNFTTDNLCFV 576 +KE A ++ G G L C + PK DD + + TD L FV Sbjct: 538 TGPVKEKIM-AVIKEWGTGRDTLR-CLALATRDTPPKREEMVLDDSARFLEYETD-LTFV 594 Query: 577 GLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAA 636 G++ M+DPPR V ++ CR AGI+VIM+TGD+ TA AI + +GI E NE V D A Sbjct: 595 GVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGE-NEEVADRAY 653 Query: 637 RL----NIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIV 692 ++P+++ +AC FAR P K IV Sbjct: 654 TGREFDDLPLAEQREACRRACC-------------------------FARVEPSHKSKIV 688 Query: 693 EGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGV 752 E Q I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV V Sbjct: 689 EYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAV 747 Query: 753 EEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISL 812 EEGR I++N+K+ I Y ++SN+ E+ L +P L + +L ++L TD +PA +L Sbjct: 748 EEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATAL 807 Query: 813 AYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFVILAENGFLPGN 872 + + DIM R PR+P+ E LIS G + FF Y I G++ Sbjct: 808 GFNPPDLDIMDRPPRSPK------EPLIS------GWL-----FFRYMAI---GGYVGAA 847 Query: 873 LVGIRLNW-----DDRTVNDLEDSYGQQWTYEQRKVVEFTCH--------TAFFVSIVVV 919 VG W D VN + ++ Q T + C T +V + Sbjct: 848 TVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTI 907 Query: 920 QWADLIICKTRRNSVFQQGMKNKILIFG-LFEETALAAFLSYCPGMDVALRMYPLKPSWW 978 + + + + S+ + I + G + +L + Y + + ++ L + W Sbjct: 908 EMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQW 967 Query: 979 FCAFPYSFLIFVYDEIRKLILR 1000 S + DEI K + R Sbjct: 968 LMVLKISLPVIGLDEILKFVAR 989 >gi|27886529 ATPase, Ca++ transporting, fast twitch 1 isoform a [Homo sapiens] Length = 1001 Score = 358 bits (918), Expect = 2e-98 Identities = 297/1042 (28%), Positives = 482/1042 (46%), Gaps = 132/1042 (12%) Query: 34 HKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSIL 93 H + EE + GLT + + L + G N L W Q + Sbjct: 5 HAKTTEECLAYFGVSETTGLTPDQVKRNLEKYGLNELPAEEGKTLWELVIEQFEDLLVRI 64 Query: 94 LWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFKN 153 L + A + F+ + G E + + V+ ++I +QE + +E+ K Sbjct: 65 LLLAACISFVLAWFEEGEETITAFVEPF---VILLILIANAIVGVWQERNAENAIEALKE 121 Query: 154 MVPQQALVIREGEK--MQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGC--KVDNSSLT 209 P+ V R K ++ A ++V GD+VE+ GD+VPAD+RI++ +VD S LT Sbjct: 122 YEPEMGKVYRADRKSVQRIKARDIVPGDIVEVAVGDKVPADIRILAIKSTTLRVDQSILT 181 Query: 210 GESEPQTRSPDCTHDNPL---ETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASG 266 GES + + D + +N+ F TN G A G+V TG T +G+I + Sbjct: 182 GESVSVIKHTEPVPDPRAVNQDKKNMLFSGTNIAAGKALGIVATTGVGTEIGKIRDQMAA 241 Query: 267 LEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSL------ILGYTWLEAVIFL----IG 316 E KTP+ +++ F + ++ V + V+ +++++ + G +W I+ + Sbjct: 242 TEQDKTPLQQKLDEFGEQLSKVISLICVAVWLINIGHFNDPVHGGSWFRGAIYYFKIAVA 301 Query: 317 IIVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRM 376 + VA +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M Sbjct: 302 LAVAAIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQM 361 Query: 377 TVAHMWFDNQIHEADTTEDQ---SGTSFDKSSHTW--------------VALSHIAGLCN 419 +V M+ +++ ++ +G+++ V L+ I LCN Sbjct: 362 SVCKMFIIDKVDGDICLLNEFSITGSTYAPEGEVLKNDKPVRPGQYDGLVELATICALCN 421 Query: 420 RAVFKGGQDNIPVLKRDVAGDASESAL----------------LKCIELSSGSVKLMRER 463 + + K G+A+E+AL L +E ++ ++R+ Sbjct: 422 DSSLDFNEAKGVYEK---VGEATETALTTLVEKMNVFNTDVRSLSKVERANACNSVIRQL 478 Query: 464 NKKVAEIPFNSTNKYQLSIHETEDPNDNRYL---LVMKGAPERILDRCSTILLQGKEQPL 520 KK + F+ K +S++ + + + + +KGAPE ++DRC+ + + PL Sbjct: 479 MKKEFTLEFSRDRK-SMSVYCSPAKSSRAAVGNKMFVKGAPEGVIDRCNYVRVGTTRVPL 537 Query: 521 DEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDD----VNFTTDNLCFV 576 +KE A ++ G G L C + PK DD + + TD L FV Sbjct: 538 TGPVKEKIM-AVIKEWGTGRDTLR-CLALATRDTPPKREEMVLDDSARFLEYETD-LTFV 594 Query: 577 GLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAA 636 G++ M+DPPR V ++ CR AGI+VIM+TGD+ TA AI + +GI E NE V D A Sbjct: 595 GVVGMLDPPRKEVTGSIQLCRDAGIRVIMITGDNKGTAIAICRRIGIFGE-NEEVADRAY 653 Query: 637 RL----NIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIV 692 ++P+++ +AC FAR P K IV Sbjct: 654 TGREFDDLPLAEQREACRRACC-------------------------FARVEPSHKSKIV 688 Query: 693 EGCQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGV 752 E Q I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV V Sbjct: 689 EYLQSYDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAV 747 Query: 753 EEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISL 812 EEGR I++N+K+ I Y ++SN+ E+ L +P L + +L ++L TD +PA +L Sbjct: 748 EEGRAIYNNMKQFIRYLISSNVGEVVCIFLTAALGLPEALIPVQLLWVNLVTDGLPATAL 807 Query: 813 AYEAAESDIMKRQPRNPRTDKLVNERLISMAYGQIGMIQALGGFFSYFVILAENGFLPGN 872 + + DIM R PR+P+ E LIS G + FF Y I G++ Sbjct: 808 GFNPPDLDIMDRPPRSPK------EPLIS------GWL-----FFRYMAI---GGYVGAA 847 Query: 873 LVGIRLNW-----DDRTVNDLEDSYGQQWTYEQRKVVEFTCH--------TAFFVSIVVV 919 VG W D VN + ++ Q T + C T +V + Sbjct: 848 TVGAAAWWFLYAEDGPHVNYSQLTHFMQCTEDNTHFEGIDCEVFEAPEPMTMALSVLVTI 907 Query: 920 QWADLIICKTRRNSVFQQGMKNKILIFG-LFEETALAAFLSYCPGMDVALRMYPLKPSWW 978 + + + + S+ + I + G + +L + Y + + ++ L + W Sbjct: 908 EMCNALNSLSENQSLLRMPPWVNIWLLGSICLSMSLHFLILYVDPLPMIFKLRALDLTQW 967 Query: 979 FCAFPYSFLIFVYDEIRKLILR 1000 S + DEI K + R Sbjct: 968 LMVLKISLPVIGLDEILKFVAR 989 >gi|118498343 ATPase, Ca++ transporting, type 2C, member 2 [Homo sapiens] Length = 946 Score = 343 bits (880), Expect = 5e-94 Identities = 274/851 (32%), Positives = 409/851 (48%), Gaps = 108/851 (12%) Query: 18 ERRDLDDLKKEVAMTEH------KMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALT 71 E+ +L ++KE +T K E++ R + D GL+ + G N Sbjct: 36 EQSELKAIEKEKKVTALPPKEACKCQKEDLARAFCVDLHTGLSEFSVTQRRLAHGWNEFV 95 Query: 72 PPPTTPEWVKFCRQLFGGFSILLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVI 131 + P W K+ Q F ILL +G+ L + + ED S I A +V+ Sbjct: 96 ADNSEPVWKKYLDQ-FKNPLILLLLGSALVSV---LTKEYEDAVS-------IATAVLVV 144 Query: 132 ITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNAEEVVVGDLVEIKGGDRVPA 191 +T F QE +S K +E MVP + +REG+ + A E+V GD+V + GDR+PA Sbjct: 145 VTVAF--IQEYRSEKSLEELTKMVPPECNCLREGKLQHLLARELVPGDVVSLSIGDRIPA 202 Query: 192 DLRIISAHGCKVDNSSLTGESEP--QTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVV 249 D+R+ VD SS TGE+EP +T SP + NI F T G +GVV+ Sbjct: 203 DIRLTEVTDLLVDESSFTGEAEPCSKTDSPLTGGGDLTTLSNIVFMGTLVQYGRGQGVVI 262 Query: 250 ATGDRTVMGRIATLASGLEVGKTPIAIEIEHFIQLITGVAVFLGVSFFILSLILGYTWLE 309 TG+ + G + + E KTP+ ++ + +T +F SF I+ LI+ W + Sbjct: 263 GTGESSQFGEVFKMMQAEETPKTPLQKSMDRLGKQLT---LF---SFGIIGLIMLIGWSQ 316 Query: 310 A----VIFLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTI 363 +F IG+ VA +PEGL V V L L RMA+K +VK L VETLG S + Sbjct: 317 GKQLLSMFTIGVSLAVAAIPEGLPIVVMVTLVLGVLRMAKKRVIVKKLPIVETLGCCSVL 376 Query: 364 CSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSH--IAGLCNRA 421 CSDKTGTLT N MTV + + + SG +D + S I N + Sbjct: 377 CSDKTGTLTANEMTVTQL-----VTSDGLRAEVSGVGYDGQGTVCLLPSKEVIKEFSNVS 431 Query: 422 VFKGGQ-----DNIPVLKRDVAGDASESALLK-CIELSSGSVKLMRERNKKVAEIPFNST 475 V K + +N + K V G +E AL+ +++ +K R K EIPF+S Sbjct: 432 VGKLVEAGCVANNAVIRKNAVMGQPTEGALMALAMKMDLSDIKNSYIRKK---EIPFSSE 488 Query: 476 NKYQLSIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPLDEEMKEAFQNAYLEL 535 K+ +++ + D + MKGA E ++ C+ G PL + + + Sbjct: 489 QKW-MAVKCSLKTEDQEDIYFMKGALEEVIRYCTMYNNGGIPLPLTPQQRSFCLQEEKRM 547 Query: 536 GGLGERVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGK 595 G LG RVL PE L F+GL+ +IDPPR V +AV Sbjct: 548 GSLGLRVLALASG--PE-----------------LGRLTFLGLVGIIDPPRVGVKEAVQV 588 Query: 596 CRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVI 655 +G+ V M+TGD TA AI + +G+ + Sbjct: 589 LSESGVSVKMITGDALETALAIGRNIGLCN------------------------------ 618 Query: 656 HGTDLKDFTSEQIDEILQNHTE------IVFARTSPQQKLIIVEGCQRQGAIVAVTGDGV 709 L+ + E++D + + VF RTSP+ KL I++ Q GAIVA+TGDGV Sbjct: 619 --GKLQAMSGEEVDSVEKGELADRVGKVSVFFRTSPKHKLKIIKALQESGAIVAMTGDGV 676 Query: 710 NDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYT 769 ND+ ALK ADIG+AMG G+DVSK+AA+MIL+DD+F++I+ VEEG+ IF N+K + + Sbjct: 677 NDAVALKSADIGIAMGQTGTDVSKEAANMILVDDDFSAIMNAVEEGKGIFYNIKNFVRFQ 736 Query: 770 LTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQPRNP 829 L+++I ++ L + N+P PL + IL I++ D PA SL E + D ++ PR+ Sbjct: 737 LSTSISALSLITLSTVFNLPSPLNAMQILWINIIMDGPPAQSLGVEPVDKDAFRQPPRSV 796 Query: 830 RTDKLVNERLI 840 R D +++ LI Sbjct: 797 R-DTILSRALI 806 >gi|209413709 ATPase, Ca++ transporting, slow twitch 2 isoform 3 [Homo sapiens] Length = 1015 Score = 333 bits (855), Expect = 4e-91 Identities = 256/854 (29%), Positives = 422/854 (49%), Gaps = 118/854 (13%) Query: 34 HKMSVEEVCRKYNTDCVQGLTHSKAQEILARDGPNALTPPPTTPEWVKFCRQLFGGFSI- 92 H +VEEV + + GL+ + +++ R G N L P ++ + F + Sbjct: 5 HTKTVEEVLGHFGVNESTGLSLEQVKKLKERWGSNEL-PAEEGKTLLELVIEQFEDLLVR 63 Query: 93 LLWIGAILCFLAYGIQAGTEDDPSGDNLYLGIVLAAVVIITGCFSYYQEAKSSKIMESFK 152 +L + A + F+ + G E + + V+ +++ +QE + +E+ K Sbjct: 64 ILLLAACISFVLAWFEEGEETITAFVEPF---VILLILVANAIVGVWQERNAENAIEALK 120 Query: 153 NMVPQQALVIREGEK--MQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTG 210 P+ V R+ K ++ A+++V GD+VEI G ++ S+ Sbjct: 121 EYEPEMGKVYRQDRKSVQRIKAKDIVPGDIVEIAG------------------ESVSVIK 162 Query: 211 ESEPQTRSPDCTHDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATLASGLEVG 270 ++P PD N + +N+ F TN G A GVVVATG T +G+I E Sbjct: 163 HTDPV---PDPRAVNQ-DKKNMLFSGTNIAAGKAMGVVVATGVNTEIGKIRDEMVATEQE 218 Query: 271 KTPIAIEIEHFIQLITGVAVFLGVSFFILSL------ILGYTWLEAVIFL----IGIIVA 320 +TP+ +++ F + ++ V + ++ +I+++ + G +W+ I+ + + VA Sbjct: 219 RTPLQQKLDEFGEQLSKVISLICIAVWIINIGHFNDPVHGGSWIRGAIYYFKIAVALAVA 278 Query: 321 NVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAH 380 +PEGL A +T CL L +RMA+KN +V++L +VETLG TS ICSDKTGTLT N+M+V Sbjct: 279 AIPEGLPAVITTCLALGTRRMAKKNAIVRSLPSVETLGCTSVICSDKTGTLTTNQMSVCR 338 Query: 381 MWFDNQIHEADTTEDQ----SGTSF---------DK--SSHTW---VALSHIAGLCNRAV 422 M+ +++ E DT +G+++ DK + H + V L+ I LCN + Sbjct: 339 MFILDRV-EGDTCSLNEFTITGSTYAPIGEVHKDDKPVNCHQYDGLVELATICALCNDSA 397 Query: 423 FKGGQDNIPVLKRDVAGDASESAL----------------LKCIELSSGSVKLMRERNKK 466 + K G+A+E+AL L IE ++ ++++ KK Sbjct: 398 LDYNEAKGVYEK---VGEATETALTCLVEKMNVFDTELKGLSKIERANACNSVIKQLMKK 454 Query: 467 VAEIPFNSTNKYQLSIHETEDPNDNRYL--LVMKGAPERILDRCSTILLQGKEQPLDEEM 524 + F+ K +S++ T + + + +KGAPE ++DRC+ I + + P+ + Sbjct: 455 EFTLEFSRDRK-SMSVYCTPNKPSRTSMSKMFVKGAPEGVIDRCTHIRVGSTKVPMTSGV 513 Query: 525 KEAFQNAYLELGGLGE--RVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFVGLMSMI 582 K+ + E G + R L + P + + + + T NL FVG + M+ Sbjct: 514 KQKIMSVIREWGSGSDTLRCLALATHDNPLRREEMHLEDSANFIKYET-NLTFVGCVGML 572 Query: 583 DPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAARLNIPV 642 DPPR V +V CR AGI+VIM+TGD+ TA AI + +GI + ED+ + Sbjct: 573 DPPRIEVASSVKLCRQAGIRVIMITGDNKGTAVAICRRIGIFGQD----EDVTS------ 622 Query: 643 SQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIV------FARTSPQQKLIIVEGCQ 696 K FT + DE+ + FAR P K IVE Q Sbjct: 623 ------------------KAFTGREFDELNPSAQRDACLNARCFARVEPSHKSKIVEFLQ 664 Query: 697 RQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGR 756 I A+TGDGVND+PALKKA+IG+AMG +G+ V+K A++M+L DDNF++IV VEEGR Sbjct: 665 SFDEITAMTGDGVNDAPALKKAEIGIAMG-SGTAVAKTASEMVLADDNFSTIVAAVEEGR 723 Query: 757 LIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEA 816 I++N+K+ I Y ++SN+ E+ L P L + +L ++L TD +PA +L + Sbjct: 724 AIYNNMKQFIRYLISSNVGEVVCIFLTAALGFPEALIPVQLLWVNLVTDGLPATALGFNP 783 Query: 817 AESDIMKRQPRNPR 830 + DIM + PRNP+ Sbjct: 784 PDLDIMNKPPRNPK 797 >gi|49249977 Na+/K+ -ATPase alpha 4 subunit isoform 2 [Homo sapiens] Length = 165 Score = 287 bits (735), Expect = 3e-77 Identities = 133/165 (80%), Positives = 151/165 (91%) Query: 849 MIQALGGFFSYFVILAENGFLPGNLVGIRLNWDDRTVNDLEDSYGQQWTYEQRKVVEFTC 908 MIQAL GFF+YFVILAENGF P +L+GIRL+W+D+ +NDLEDSYGQQWTYEQRKVVEFTC Sbjct: 1 MIQALAGFFTYFVILAENGFRPVDLLGIRLHWEDKYLNDLEDSYGQQWTYEQRKVVEFTC 60 Query: 909 HTAFFVSIVVVQWADLIICKTRRNSVFQQGMKNKILIFGLFEETALAAFLSYCPGMDVAL 968 TAFFV+IVVVQWADLII KTRRNS+FQQGM+NK+LIFG+ EET LAAFLSY PGMDVAL Sbjct: 61 QTAFFVTIVVVQWADLIISKTRRNSLFQQGMRNKVLIFGILEETLLAAFLSYTPGMDVAL 120 Query: 969 RMYPLKPSWWFCAFPYSFLIFVYDEIRKLILRRNPGGWVEKETYY 1013 RMYPLK +WW CA PYS LIFVYDEIRKL++R++P GWVE+ETYY Sbjct: 121 RMYPLKITWWLCAIPYSILIFVYDEIRKLLIRQHPDGWVERETYY 165 >gi|48255949 plasma membrane calcium ATPase 2 isoform 2 [Homo sapiens] Length = 1198 Score = 271 bits (694), Expect = 2e-72 Identities = 268/945 (28%), Positives = 436/945 (46%), Gaps = 157/945 (16%) Query: 17 KERRDLDDLKKEVAMTEHKMS---VEEVCRKYNTDCVQGLTHSKAQEILARD---GPNAL 70 +E R L +L+ A+ + K + E +CR+ T V+GL + A ++ R G N + Sbjct: 29 EELRSLMELRGTEAVVKIKETYGDTEAICRRLKTSPVEGLPGT-APDLEKRKQIFGQNFI 87 Query: 71 TPPPTTPEWVKFCRQLFGGFS-ILLWIGAILCFLAYGI----------------QAGTED 113 PP P+ F + ++ + L I I ++ G+ Q G ED Sbjct: 88 --PPKKPK--TFLQLVWEALQDVTLIILEIAAIISLGLSFYHPPGEGNEGCATAQGGAED 143 Query: 114 DPSGDNLYL---GIVLAAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQ 169 + + ++ I+L+ + V++ F+ + + K + ++S + Q+ V+R G+ +Q Sbjct: 144 EGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVVRAGQVVQ 202 Query: 170 VNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLET 229 + E+VVGD+ ++K GD +PAD I + K+D SSLTGES+ +S D +P+ Sbjct: 203 IPVAEIVVGDIAQVKYGDLLPADGLFIQGNDLKIDESSLTGESDQVRKSVD---KDPM-- 257 Query: 230 RNITFFSTNCVEGTARGVVVATGDRTVMGRIATL--------------------ASGLEV 269 T+ +EG+ R +V A G + G I TL A+ +E+ Sbjct: 258 ---LLSGTHVMEGSGRMLVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKAKQQDGAAAMEM 314 Query: 270 ----------------------------GK-TPIAIEIEHFIQLITGVAVFLGVSFFILS 300 GK T +A++I +++ + V + V +F + Sbjct: 315 QPLKSAEGGDADDRKKASMHKKEKSVLQGKLTKLAVQIGKAGLVMSAITVIILVLYFTVD 374 Query: 301 --LILGYTWLEAV----------IFLIGI--IVANVPEGLLATVTVCLTLTAKRMARKNC 346 ++ WL F+IG+ +V VPEGL VT+ L + K+M + N Sbjct: 375 TFVVNKKPWLPECTPVYVQYFVKFFIIGVTVLVVAVPEGLPLAVTISLAYSVKKMMKDNN 434 Query: 347 LVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWFDNQIHEADTTEDQSGTSFDKSSH 406 LV++L+A ET+G+ + ICSDKTGTLT NRMTV + + +H + + S + K+ Sbjct: 435 LVRHLDACETMGNATAICSDKTGTLTTNRMTVVQAYVGD-VHYKEIPDPSSINT--KTME 491 Query: 407 TWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDASESALLKCI---ELSSGSVKLMRER 463 + I + ++ L R V G+ +E LL + + V+ Sbjct: 492 LLINAIAINSAYTTKILPPEKEG--ALPRQV-GNKTECGLLGFVLDLKQDYEPVRSQMPE 548 Query: 464 NKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKGAPERILDRCSTILLQGKEQPL--- 520 K FNS K ++ + D + Y KGA E +L +C IL G +P Sbjct: 549 EKLYKVYTFNSVRKSMSTVIKLPDESFRMY---SKGASEIVLKKCCKIL-NGAGEPRVFR 604 Query: 521 ----DEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQFPKGFAFDCDDVNFTTDNLCFV 576 DE +K+ + + G R + C Y FP D D+ N + L + Sbjct: 605 PRDRDEMVKKVIEPMACD----GLRTI--CVAY---RDFPSSPEPDWDNENDILNELTCI 655 Query: 577 GLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAKAIAKGVGIISEGNETVEDIAA 636 ++ + DP R VP+A+ KC+ AGI V MVTGD+ TA+AIA GII G + + Sbjct: 656 CVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTARAIAIKCGIIHPGEDFLCLEGK 715 Query: 637 RLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGC- 695 N + R+ K + E+ID+I V AR+SP K +V+G Sbjct: 716 EFNRRI-----RNEKG---------EIEQERIDKIWPKLR--VLARSSPTDKHTLVKGII 759 Query: 696 ----QRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTG 751 Q +VAVTGDG ND PALKKAD+G AMGIAG+DV+K+A+D+IL DDNF+SIV Sbjct: 760 DSTHTEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFSSIVKA 819 Query: 752 VEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAIS 811 V GR ++D++ K + + LT N+ + PL + +L ++L D +++ Sbjct: 820 VMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTFASLA 879 Query: 812 LAYEAAESDIMKRQP---RNPRTDKLVNERLISMAYGQIGMIQAL 853 LA E ++ R+P P + + + ++ A Q+ +I L Sbjct: 880 LATEPPTETLLLRKPYGRNKPLISRTMMKNILGHAVYQLALIFTL 924 >gi|48255955 plasma membrane calcium ATPase 3 isoform 3b [Homo sapiens] Length = 1220 Score = 267 bits (682), Expect = 4e-71 Identities = 249/846 (29%), Positives = 390/846 (46%), Gaps = 141/846 (16%) Query: 107 IQAGTEDDPSGDNLYL---GIVLAAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVI 162 + G ED+ + ++ I+L+ + V++ F+ + + K + ++S + Q+ VI Sbjct: 140 VSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVI 198 Query: 163 REGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCT 222 R G+ +QV +VVGD+ ++K GD +PAD +I A+ K+D SSLTGES+ +S D Sbjct: 199 RNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSAD-- 256 Query: 223 HDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATL--ASGLEVGKT-------- 272 +P+ T+ +EG+ R VV A G + G I TL A G E K Sbjct: 257 -KDPM-----LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQD 310 Query: 273 ---------------PIAIEIEHFIQL--------------------------ITGVAVF 291 +A+E++ +T +AV Sbjct: 311 GAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQ 370 Query: 292 LGVSFFILSLIL----------------GYTWLE----------AVIFLIG--IIVANVP 323 +G + ++S I G TWL F+IG ++V VP Sbjct: 371 IGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVP 430 Query: 324 EGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWF 383 EGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV + Sbjct: 431 EGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYL 490 Query: 384 -DNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDAS 442 D E + D H A+S + + + + +P R V G+ + Sbjct: 491 GDTHYKEIPAPSALTPKILDLLVH---AISINSAYTTKILPPEKEGALP---RQV-GNKT 543 Query: 443 ESALLKCIELSSGSVKLMRER---NKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKG 499 E ALL + + +RE+ +K FNS K ++ D + L KG Sbjct: 544 ECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMP---DGGFRLFSKG 600 Query: 500 APERILDRCSTILLQGKE----QPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQF 555 A E +L +C+ IL E +P D + + + + G R + C Y F Sbjct: 601 ASEILLKKCTNILNSNGELRGFRPRDRD--DMVRKIIEPMACDGLRTI--CIAY---RDF 653 Query: 556 PKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAK 615 G D D+ N +L + ++ + DP R VP+A+ KC+ AGI V MVTGD+ TA+ Sbjct: 654 SAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTAR 713 Query: 616 AIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNH 675 AIA GII G + L + + N R + + E++D++ Sbjct: 714 AIAAKCGIIQPGEDF-------LCLEGKEFNRRIR-------NEKGEIEQERLDKVWPKL 759 Query: 676 TEIVFARTSPQQKLIIVEG-----CQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSD 730 V AR+SP K +V+G Q +VAVTGDG ND PALKKAD+G AMGIAG+D Sbjct: 760 R--VLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTD 817 Query: 731 VSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPL 790 V+K+A+D+IL DDNF SIV V GR ++D++ K + + LT N+ + Sbjct: 818 VAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDS 877 Query: 791 PLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQP---RNPRTDKLVNERLISMAYGQI 847 PL + +L ++L D +++LA E ++ R+P P + + + ++ A Q+ Sbjct: 878 PLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQL 937 Query: 848 GMIQAL 853 +I L Sbjct: 938 AIIFTL 943 >gi|48255953 plasma membrane calcium ATPase 3 isoform 3a [Homo sapiens] Length = 1173 Score = 267 bits (682), Expect = 4e-71 Identities = 249/846 (29%), Positives = 390/846 (46%), Gaps = 141/846 (16%) Query: 107 IQAGTEDDPSGDNLYL---GIVLAAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVI 162 + G ED+ + ++ I+L+ + V++ F+ + + K + ++S + Q+ VI Sbjct: 140 VSGGAEDEGEAEAGWIEGAAILLSVICVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVI 198 Query: 163 REGEKMQVNAEEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCT 222 R G+ +QV +VVGD+ ++K GD +PAD +I A+ K+D SSLTGES+ +S D Sbjct: 199 RNGQLLQVPVAALVVGDIAQVKYGDLLPADGVLIQANDLKIDESSLTGESDHVRKSAD-- 256 Query: 223 HDNPLETRNITFFSTNCVEGTARGVVVATGDRTVMGRIATL--ASGLEVGKT-------- 272 +P+ T+ +EG+ R VV A G + G I TL A G E K Sbjct: 257 -KDPM-----LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTLLGAGGEEEEKKDKKGKQQD 310 Query: 273 ---------------PIAIEIEHFIQL--------------------------ITGVAVF 291 +A+E++ +T +AV Sbjct: 311 GAMESSQTKAKKQDGAVAMEMQPLKSAEGGEMEEREKKKANAPKKEKSVLQGKLTKLAVQ 370 Query: 292 LGVSFFILSLIL----------------GYTWLE----------AVIFLIG--IIVANVP 323 +G + ++S I G TWL F+IG ++V VP Sbjct: 371 IGKAGLVMSAITVIILVLYFVIETFVVEGRTWLAECTPVYVQYFVKFFIIGVTVLVVAVP 430 Query: 324 EGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMTVAHMWF 383 EGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMTV + Sbjct: 431 EGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTTNRMTVVQSYL 490 Query: 384 -DNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDVAGDAS 442 D E + D H A+S + + + + +P R V G+ + Sbjct: 491 GDTHYKEIPAPSALTPKILDLLVH---AISINSAYTTKILPPEKEGALP---RQV-GNKT 543 Query: 443 ESALLKCIELSSGSVKLMRER---NKKVAEIPFNSTNKYQLSIHETEDPNDNRYLLVMKG 499 E ALL + + +RE+ +K FNS K ++ D + L KG Sbjct: 544 ECALLGFVLDLKRDFQPVREQIPEDKLYKVYTFNSVRKSMSTVIRMP---DGGFRLFSKG 600 Query: 500 APERILDRCSTILLQGKE----QPLDEEMKEAFQNAYLELGGLGERVLGFCHYYLPEEQF 555 A E +L +C+ IL E +P D + + + + G R + C Y F Sbjct: 601 ASEILLKKCTNILNSNGELRGFRPRDRD--DMVRKIIEPMACDGLRTI--CIAY---RDF 653 Query: 556 PKGFAFDCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGIKVIMVTGDHPITAK 615 G D D+ N +L + ++ + DP R VP+A+ KC+ AGI V MVTGD+ TA+ Sbjct: 654 SAGQEPDWDNENEVVGDLTCIAVVGIEDPVRPEVPEAIRKCQRAGITVRMVTGDNINTAR 713 Query: 616 AIAKGVGIISEGNETVEDIAARLNIPVSQVNPRDAKACVIHGTDLKDFTSEQIDEILQNH 675 AIA GII G + L + + N R + + E++D++ Sbjct: 714 AIAAKCGIIQPGEDF-------LCLEGKEFNRRIR-------NEKGEIEQERLDKVWPKL 759 Query: 676 TEIVFARTSPQQKLIIVEG-----CQRQGAIVAVTGDGVNDSPALKKADIGVAMGIAGSD 730 V AR+SP K +V+G Q +VAVTGDG ND PALKKAD+G AMGIAG+D Sbjct: 760 R--VLARSSPTDKHTLVKGIIDSTTGEQRQVVAVTGDGTNDGPALKKADVGFAMGIAGTD 817 Query: 731 VSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTLTSNIPEITPFLLFIMANIPL 790 V+K+A+D+IL DDNF SIV V GR ++D++ K + + LT N+ + Sbjct: 818 VAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQLTVNVVAVIVAFTGACITQDS 877 Query: 791 PLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQP---RNPRTDKLVNERLISMAYGQI 847 PL + +L ++L D +++LA E ++ R+P P + + + ++ A Q+ Sbjct: 878 PLKAVQMLWVNLIMDTFASLALATEPPTESLLLRKPYGRDKPLISRTMMKNILGHAVYQL 937 Query: 848 GMIQAL 853 +I L Sbjct: 938 AIIFTL 943 >gi|48255947 plasma membrane calcium ATPase 1 isoform 1a [Homo sapiens] Length = 1176 Score = 229 bits (583), Expect = 1e-59 Identities = 197/626 (31%), Positives = 305/626 (48%), Gaps = 90/626 (14%) Query: 272 TPIAIEIEHFIQLITGVAVFLGVSFFILSL--ILGYTWLEAV----------IFLIGI-- 317 T +A++I L++ + V + V +F++ + WL F+IG+ Sbjct: 367 TKLAVQIGKAGLLMSAITVIILVLYFVIDTFWVQKRPWLAECTPIYIQYFVKFFIIGVTV 426 Query: 318 IVANVPEGLLATVTVCLTLTAKRMARKNCLVKNLEAVETLGSTSTICSDKTGTLTQNRMT 377 +V VPEGL VT+ L + K+M + N LV++L+A ET+G+ + ICSDKTGTLT NRMT Sbjct: 427 LVVAVPEGLPLAVTISLAYSVKKMMKDNNLVRHLDACETMGNATAICSDKTGTLTMNRMT 486 Query: 378 VAHMWFDNQIHEADTTEDQSGTSFDKSSHTWVALSHIAGLCNRAVFKGGQDNIPVLKRDV 437 V + N+ H E ++ + S+ +S ++ + + +P R V Sbjct: 487 VVQAYI-NEKHYKKVPEPEAIPP-NILSYLVTGISVNCAYTSKILPPEKEGGLP---RHV 541 Query: 438 AGDASESALLKCIELSSGSVKLMRERNKKVAEIP---------FNSTNKYQLSIHETEDP 488 G+ +E ALL + + L R+ EIP FNS K ++ + Sbjct: 542 -GNKTECALLGLL------LDLKRDYQDVRNEIPEEALYKVYTFNSVRKSMSTVLKN--- 591 Query: 489 NDNRYLLVMKGAPERILDRCSTILLQGKEQPL------DEEMKEAFQNAYLELGGLGERV 542 +D Y + KGA E IL +C IL E + D+ +K + E GL Sbjct: 592 SDGSYRIFSKGASEIILKKCFKILSANGEAKVFRPRDRDDIVKTVIEPMASE--GLRTIC 649 Query: 543 LGFCHYYLPEEQFPKGFAF-DCDDVNFTTDNLCFVGLMSMIDPPRAAVPDAVGKCRSAGI 601 L F FP G + D+ N L + ++ + DP R VPDA+ KC+ AGI Sbjct: 650 LAF-------RDFPAGEPEPEWDNENDIVTGLTCIAVVGIEDPVRPEVPDAIKKCQRAGI 702 Query: 602 KVIMVTGDHPITAKAIAKGVGIISEGNETV----EDIAARLNIPVSQVNPRDAKACVIHG 657 V MVTGD+ TA+AIA GI+ G + + +D R+ R+ K Sbjct: 703 TVRMVTGDNINTARAIATKCGILHPGEDFLCLEGKDFNRRI---------RNEKG----- 748 Query: 658 TDLKDFTSEQIDEILQNHTEIVFARTSPQQKLIIVEGC-------QRQGAIVAVTGDGVN 710 + E+ID+I V AR+SP K +V+G QRQ +VAVTGDG N Sbjct: 749 ----EIEQERIDKIWPKLR--VLARSSPTDKHTLVKGIIDSTVSDQRQ--VVAVTGDGTN 800 Query: 711 DSPALKKADIGVAMGIAGSDVSKQAADMILLDDNFASIVTGVEEGRLIFDNLKKSIAYTL 770 D PALKKAD+G AMGIAG+DV+K+A+D+IL DDNF SIV V GR ++D++ K + + L Sbjct: 801 DGPALKKADVGFAMGIAGTDVAKEASDIILTDDNFTSIVKAVMWGRNVYDSISKFLQFQL 860 Query: 771 TSNIPEITPFLLFIMANIPLPLGTITILCIDLGTDMVPAISLAYEAAESDIMKRQP---R 827 T N+ + PL + +L ++L D + +++LA E ++ R+P Sbjct: 861 TVNVVAVIVAFTGACITQDSPLKAVQMLWVNLIMDTLASLALATEPPTESLLLRKPYGRN 920 Query: 828 NPRTDKLVNERLISMAYGQIGMIQAL 853 P + + + ++ A+ Q+ ++ L Sbjct: 921 KPLISRTMMKNILGHAFYQLVVVFTL 946 Score = 70.5 bits (171), Expect = 8e-12 Identities = 75/271 (27%), Positives = 125/271 (46%), Gaps = 44/271 (16%) Query: 18 ERRDLDDLKKEVAMTEHKMSVEEVCRKYNTDCVQGLTHSKAQEILARD---GPNALTPPP 74 E R D L+K + E V +C K T +GL+ + A ++ R+ G N + PP Sbjct: 39 ELRSTDALRK---IQESYGDVYGICTKLKTSPNEGLSGNPA-DLERREAVFGKNFI--PP 92 Query: 75 TTPEWVKFCRQLFGGFS-ILLWIGAILCFLAYGIQAGTEDDPSGDNLYLG---------- 123 P+ F + ++ + L I I ++ G+ P GDN G Sbjct: 93 KKPK--TFLQLVWEALQDVTLIILEIAAIVSLGLSF--YQPPEGDNALCGEVSVGEEEGE 148 Query: 124 ----------IVLAAV-VIITGCFSYYQEAKSSKIMESFKNMVPQQALVIREGEKMQVNA 172 I+L+ V V++ F+ + + K + ++S + Q+ VIR G+ +Q+ Sbjct: 149 GETGWIEGAAILLSVVCVVLVTAFNDWSKEKQFRGLQS-RIEQEQKFTVIRGGQVIQIPV 207 Query: 173 EEVVVGDLVEIKGGDRVPADLRIISAHGCKVDNSSLTGESEPQTRSPDCTHDNPLETRNI 232 ++ VGD+ ++K GD +PAD +I + K+D SSLTGES+ +S L+ + Sbjct: 208 ADITVGDIAQVKYGDLLPADGILIQGNDLKIDESSLTGESDHVKKS--------LDKDPL 259 Query: 233 TFFSTNCVEGTARGVVVATGDRTVMGRIATL 263 T+ +EG+ R VV A G + G I TL Sbjct: 260 LLSGTHVMEGSGRMVVTAVGVNSQTGIIFTL 290 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.320 0.137 0.407 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 36,926,717 Number of Sequences: 37866 Number of extensions: 1608723 Number of successful extensions: 4268 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 66 Number of HSP's successfully gapped in prelim test: 18 Number of HSP's that attempted gapping in prelim test: 3925 Number of HSP's gapped (non-prelim): 179 length of query: 1013 length of database: 18,247,518 effective HSP length: 112 effective length of query: 901 effective length of database: 14,006,526 effective search space: 12619879926 effective search space used: 12619879926 T: 11 A: 40 X1: 16 ( 7.4 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.8 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.