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Search of human proteins with 227430327
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|227430327 calsequestrin 1 [Homo sapiens]
(396 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|227430327 calsequestrin 1 [Homo sapiens] 796 0.0
gi|119395727 cardiac calsequestrin 2 precursor [Homo sapiens] 548 e-156
gi|52487191 thioredoxin domain containing 4 (endoplasmic reticul... 55 1e-07
gi|4758304 protein disulfide isomerase A4 [Homo sapiens] 54 2e-07
gi|38505222 thioredoxin domain containing 10 [Homo sapiens] 50 3e-06
gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo s... 45 9e-05
gi|28372543 protein disulfide isomerase-like, testis expressed [... 39 0.006
gi|19923665 BRI3-binding protein [Homo sapiens] 39 0.011
gi|239752832 PREDICTED: similar to SET translocation [Homo sapiens] 36 0.069
gi|239747380 PREDICTED: similar to SET translocation [Homo sapiens] 36 0.069
gi|239741205 PREDICTED: similar to SET translocation [Homo sapiens] 36 0.069
gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens] 36 0.069
gi|189011568 adenomatous polyposis coli [Homo sapiens] 34 0.26
gi|189011566 adenomatous polyposis coli [Homo sapiens] 34 0.26
gi|53759122 adenomatous polyposis coli [Homo sapiens] 34 0.26
gi|158631177 homeodomain leucine zipper protein [Homo sapiens] 34 0.26
gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens] 33 0.45
gi|5031973 protein disulfide isomerase A6 [Homo sapiens] 33 0.59
gi|14110378 neighbor of BRCA1 gene 1 [Homo sapiens] 32 0.77
gi|14110375 neighbor of BRCA1 gene 1 [Homo sapiens] 32 0.77
gi|14110381 neighbor of BRCA1 gene 1 [Homo sapiens] 32 0.77
gi|210032580 SET domain containing 1B [Homo sapiens] 32 1.0
gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo s... 32 1.3
gi|48762709 SAM domain, SH3 domain and nuclear localization sign... 32 1.3
gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo... 32 1.3
gi|42516574 tripartite motif-containing 41 isoform 2 [Homo sapiens] 32 1.3
gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens] 32 1.3
gi|75677335 digestive-organ expansion factor homolog [Homo sapiens] 32 1.3
gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens] 31 1.7
gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens] 31 1.7
>gi|227430327 calsequestrin 1 [Homo sapiens]
Length = 396
Score = 796 bits (2057), Expect = 0.0
Identities = 396/396 (100%), Positives = 396/396 (100%)
Query: 1 MSATDRMGPRAVPGLRLALLLLLVLGTPKSGVQGQEGLDFPEYDGVDRVINVNAKNYKNV 60
MSATDRMGPRAVPGLRLALLLLLVLGTPKSGVQGQEGLDFPEYDGVDRVINVNAKNYKNV
Sbjct: 1 MSATDRMGPRAVPGLRLALLLLLVLGTPKSGVQGQEGLDFPEYDGVDRVINVNAKNYKNV 60
Query: 61 FKKYEVLALLYHEPPEDDKASQRQFEMEELILELAAQVLEDKGVGFGLVDSEKDAAVAKK 120
FKKYEVLALLYHEPPEDDKASQRQFEMEELILELAAQVLEDKGVGFGLVDSEKDAAVAKK
Sbjct: 61 FKKYEVLALLYHEPPEDDKASQRQFEMEELILELAAQVLEDKGVGFGLVDSEKDAAVAKK 120
Query: 121 LGLTEVDSMYVFKGDEVIEYDGEFSADTIVEFLLDVLEDPVELIEGERELQAFENIEDEI 180
LGLTEVDSMYVFKGDEVIEYDGEFSADTIVEFLLDVLEDPVELIEGERELQAFENIEDEI
Sbjct: 121 LGLTEVDSMYVFKGDEVIEYDGEFSADTIVEFLLDVLEDPVELIEGERELQAFENIEDEI 180
Query: 181 KLIGYFKSKDSEHYKAFEDAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYEAFMEEPV 240
KLIGYFKSKDSEHYKAFEDAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYEAFMEEPV
Sbjct: 181 KLIGYFKSKDSEHYKAFEDAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYEAFMEEPV 240
Query: 241 TIPDKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGIHIVAFAEEADPDGFEFL 300
TIPDKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGIHIVAFAEEADPDGFEFL
Sbjct: 241 TIPDKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGIHIVAFAEEADPDGFEFL 300
Query: 301 ETLKAVAQDNTENPDLSIIWIDPDDFPLLVPYWEKTFDIDLSAPQIGVVNVTDADSVWME 360
ETLKAVAQDNTENPDLSIIWIDPDDFPLLVPYWEKTFDIDLSAPQIGVVNVTDADSVWME
Sbjct: 301 ETLKAVAQDNTENPDLSIIWIDPDDFPLLVPYWEKTFDIDLSAPQIGVVNVTDADSVWME 360
Query: 361 MDDEEDLPSAEELEDWLEDVLEGEINTEDDDDDDDD 396
MDDEEDLPSAEELEDWLEDVLEGEINTEDDDDDDDD
Sbjct: 361 MDDEEDLPSAEELEDWLEDVLEGEINTEDDDDDDDD 396
>gi|119395727 cardiac calsequestrin 2 precursor [Homo sapiens]
Length = 399
Score = 548 bits (1412), Expect = e-156
Identities = 251/367 (68%), Positives = 316/367 (86%)
Query: 30 SGVQGQEGLDFPEYDGVDRVINVNAKNYKNVFKKYEVLALLYHEPPEDDKASQRQFEMEE 89
S + +EGL+FP YDG DRV++++ KN+K V KKY++L L YHEP DK +Q+QF+++E
Sbjct: 15 SSCRAEEGLNFPTYDGKDRVVSLSEKNFKQVLKKYDLLCLYYHEPVSSDKVTQKQFQLKE 74
Query: 90 LILELAAQVLEDKGVGFGLVDSEKDAAVAKKLGLTEVDSMYVFKGDEVIEYDGEFSADTI 149
++LEL AQVLE K +GF +VD++K+A +AKKLG E S+Y+ KGD IE+DGEF+AD +
Sbjct: 75 IVLELVAQVLEHKAIGFVMVDAKKEAKLAKKLGFDEEGSLYILKGDRTIEFDGEFAADVL 134
Query: 150 VEFLLDVLEDPVELIEGERELQAFENIEDEIKLIGYFKSKDSEHYKAFEDAAEEFHPYIP 209
VEFLLD++EDPVE+I + E+QAFE IED IKLIG+FKS+DSE+YKAFE+AAE F PYI
Sbjct: 135 VEFLLDLIEDPVEIISSKLEVQAFERIEDYIKLIGFFKSEDSEYYKAFEEAAEHFQPYIK 194
Query: 210 FFATFDSKVAKKLTLKLNEIDFYEAFMEEPVTIPDKPNSEEEIVNFVEEHRRSTLRKLKP 269
FFATFD VAKKL+LK+NE+DFYE FM+EP+ IP+KP +EEE+V FV+EH+R TLR+L+P
Sbjct: 195 FFATFDKGVAKKLSLKMNEVDFYEPFMDEPIAIPNKPYTEEELVEFVKEHQRPTLRRLRP 254
Query: 270 ESMYETWEDDMDGIHIVAFAEEADPDGFEFLETLKAVAQDNTENPDLSIIWIDPDDFPLL 329
E M+ETWEDD++GIHIVAFAE++DPDG+EFLE LK VA+DNT+NPDLSI+WIDPDDFPLL
Sbjct: 255 EEMFETWEDDLNGIHIVAFAEKSDPDGYEFLEILKQVARDNTDNPDLSILWIDPDDFPLL 314
Query: 330 VPYWEKTFDIDLSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLEGEINTED 389
V YWEKTF IDL PQIGVVNVTDADSVWME+ D++DLP+AEELEDW+EDVL G+INTED
Sbjct: 315 VAYWEKTFKIDLFRPQIGVVNVTDADSVWMEIPDDDDLPTAEELEDWIEDVLSGKINTED 374
Query: 390 DDDDDDD 396
DD+DDDD
Sbjct: 375 DDEDDDD 381
>gi|52487191 thioredoxin domain containing 4 (endoplasmic reticulum)
[Homo sapiens]
Length = 406
Score = 55.1 bits (131), Expect = 1e-07
Identities = 34/136 (25%), Positives = 70/136 (51%), Gaps = 9/136 (6%)
Query: 86 EMEELILELAAQVLEDK-----GVGFGLVDSEKDAAVAKKLGLTEVDSMYVFKGDEVI-- 138
+M I E A+ V++++ V F VD ++ + +A++ +++ ++ +F+ ++
Sbjct: 62 QMLHPIFEEASDVIKEEFPNENQVVFARVDCDQHSDIAQRYRISKYPTLKLFRNGMMMKR 121
Query: 139 EYDGEFSADTIVEFLLDVLEDPVELIEGERELQAFENIEDEIKLIGYFKSKDSEHYKAFE 198
EY G+ S + +++ DP++ I E+ + + I IGYF+ KDS++Y+ FE
Sbjct: 122 EYRGQRSVKALADYIRQQKSDPIQEIRDLAEITTLDRSKRNI--IGYFEQKDSDNYRVFE 179
Query: 199 DAAEEFHPYIPFFATF 214
A H F + F
Sbjct: 180 RVANILHDDCAFLSAF 195
>gi|4758304 protein disulfide isomerase A4 [Homo sapiens]
Length = 645
Score = 53.9 bits (128), Expect = 2e-07
Identities = 32/139 (23%), Positives = 69/139 (49%), Gaps = 2/139 (1%)
Query: 93 ELAAQVLEDKG--VGFGLVDSEKDAAVAKKLGLTEVDSMYVFKGDEVIEYDGEFSADTIV 150
E AA+ L + + VD+ + +AK+ ++ ++ +F+ +Y+G IV
Sbjct: 217 EKAAKELSKRSPPIPLAKVDATAETDLAKRFDVSGYPTLKIFRKGRPYDYNGPREKYGIV 276
Query: 151 EFLLDVLEDPVELIEGERELQAFENIEDEIKLIGYFKSKDSEHYKAFEDAAEEFHPYIPF 210
+++++ P + I +++Q F D++ +IG FK + Y+ ++DAA F
Sbjct: 277 DYMIEQSGPPSKEILTLKQVQEFLKDGDDVIIIGVFKGESDPAYQQYQDAANNLREDYKF 336
Query: 211 FATFDSKVAKKLTLKLNEI 229
TF +++AK L + ++
Sbjct: 337 HHTFSTEIAKFLKVSQGQL 355
>gi|38505222 thioredoxin domain containing 10 [Homo sapiens]
Length = 454
Score = 50.4 bits (119), Expect = 3e-06
Identities = 58/299 (19%), Positives = 125/299 (41%), Gaps = 22/299 (7%)
Query: 99 LEDKGVG----FGLVDSEKDAAVAKKLGLTEVDSMYVFKGDEVIEYDGEFSADTIVEFLL 154
LE K +G G +D+ +++A + G+ ++ + KGD Y G + D I+EF
Sbjct: 68 LEMKSIGSPVKVGKMDATSYSSIASEFGVRGYPTIKLLKGDLAYNYRGPRTKDDIIEFAH 127
Query: 155 DVLEDPVELIEGERELQAFENIEDEIKLIGYFKSKDSEHYKAFEDAAEEFHPYIPFFATF 214
V LI Q FE+++ ++ + +S + + DAA E Y FF+
Sbjct: 128 RV---SGALIRPLPSQQMFEHMQKRHRVFFVYVGGESPLKEKYIDAASELIVYTYFFSAS 184
Query: 215 DSKVAKKLTLKLNEIDFYEAFMEEPVTIPDKPNSEEEIVNFVEEHRRSTLRKLKPESMYE 274
+ V + +TLK E+ F +E + D+ + ++ +++ R + +YE
Sbjct: 185 EEVVPEYVTLK--EMPAVLVFKDETYFVYDE-YEDGDLSSWINRERFQNYLAMDGFLLYE 241
Query: 275 TWEDDMDGIHIVAFAEEADPDGFEFLETLKAVAQDNTE--NPDLSIIWIDPDDFPLLVPY 332
+ V + + ++ VA+D + + D +D +D Y
Sbjct: 242 LGDTGKLVALAVIDEKNTSVEHTRLKSIIQEVARDYRDLFHRDFQFGHMDGND------Y 295
Query: 333 WEKTFDIDLSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLEGEINTEDDD 391
+L+ P + V+N ++ + + + + E++ ++ ++L+G + + D
Sbjct: 296 INTLLMDELTVPTVVVLNTSNQQYFLL----DRQIKNVEDMVQFINNILDGTVEAQGGD 350
>gi|20070125 prolyl 4-hydroxylase, beta subunit precursor [Homo
sapiens]
Length = 508
Score = 45.4 bits (106), Expect = 9e-05
Identities = 78/385 (20%), Positives = 158/385 (41%), Gaps = 49/385 (12%)
Query: 15 LRLALLLLLVLGTPKSGVQGQEGLDFPEYDGVDRVINVNAKNYKNVFKKYEVLALLYHEP 74
LR ALL L V ++ D PE + D V+ + N+ ++ L + ++ P
Sbjct: 2 LRRALLCLAVAALVRA--------DAPEEE--DHVLVLRKSNFAEALAAHKYLLVEFYAP 51
Query: 75 ---------PEDDKASQRQFEMEELILELAAQVLEDKGVGFGLVDSEKDAAVAKKLGLTE 125
PE KA+ + L A+ E + VD+ +++ +A++ G+
Sbjct: 52 WCGHCKALAPEYAKAAGK----------LKAEGSE---IRLAKVDATEESDLAQQYGVRG 98
Query: 126 VDSMYVFKGDEVI---EYDGEFSADTIVEFLLDVLEDPVELIEGERELQAFENIEDEIKL 182
++ F+ + EY AD IV +L + ++ E+ +
Sbjct: 99 YPTIKFFRNGDTASPKEYTAGREADDIVNWLKKRTGPAATTLPDGAAAESLVE-SSEVAV 157
Query: 183 IGYFKSKDSEHYKAFEDAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYEAFMEEPVTI 242
IG+FK +S+ K F AAE IPF T +S V K L + + ++ F E
Sbjct: 158 IGFFKDVESDSAKQFLQAAEAIDD-IPFGITSNSDVFSKYQLDKDGVVLFKKFDEGRNNF 216
Query: 243 PDKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGIHIVAFAEEADPDGFEFLET 302
+ ++E +++F++ ++ + + ++ + + ++ HI+ F ++ D L
Sbjct: 217 EGEV-TKENLLDFIKHNQLPLVIEFTEQTAPKIFGGEIK-THILLFLPKSVSDYDGKLSN 274
Query: 303 LKAVAQDNTENPDLSIIWIDPD--DFPLLVPYWEKTFDIDLSAPQIGVVNVTDADSVWME 360
K A+ + + I+ID D D ++ ++ L + V + + +
Sbjct: 275 FKTAAE--SFKGKILFIFIDSDHTDNQRILEFF------GLKKEECPAVRLITLEEEMTK 326
Query: 361 MDDEEDLPSAEELEDWLEDVLEGEI 385
E + +AE + ++ LEG+I
Sbjct: 327 YKPESEELTAERITEFCHRFLEGKI 351
>gi|28372543 protein disulfide isomerase-like, testis expressed
[Homo sapiens]
Length = 584
Score = 39.3 bits (90), Expect = 0.006
Identities = 40/198 (20%), Positives = 83/198 (41%), Gaps = 12/198 (6%)
Query: 67 LALLYHEPPEDDKASQRQFEMEELILELAAQVLEDKGVGFGLVDSEKDAAVAKKLGLTEV 126
L +L+H P + Q + EEL + G+GFG VD + + ++ G+T+
Sbjct: 63 LMVLFHNP----SSKQSRNLAEELGKAVEIMGKGKNGIGFGKVDITIEKELQQEFGITKA 118
Query: 127 DSMYVF---KGDEVIEYDGEFSADTIVEFLLDVLEDPVELIEGERELQAFENIEDEIKLI 183
+ +F E I G + +V +L + L ++ F I + ++
Sbjct: 119 PELKLFFEGNRSEPISCKGVVESAALVVWLRRQISQKAFLFNSSEQVAEFV-ISRPLVIV 177
Query: 184 GYFKSKDSEHYKAFEDAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYE--AFMEEPVT 241
G+F+ + E + F D ++F P + F V + + L+ + ++ +
Sbjct: 178 GFFQDLEEEVAELFYDVIKDF-PELTFGVITIGNVIGRFHVTLDSVLVFKKGKIVNRQKL 236
Query: 242 IPDKPNSEEEIVNFVEEH 259
I D N ++E+ +++H
Sbjct: 237 INDSTN-KQELNRVIKQH 253
>gi|19923665 BRI3-binding protein [Homo sapiens]
Length = 251
Score = 38.5 bits (88), Expect = 0.011
Identities = 25/68 (36%), Positives = 34/68 (50%)
Query: 1 MSATDRMGPRAVPGLRLALLLLLVLGTPKSGVQGQEGLDFPEYDGVDRVINVNAKNYKNV 60
M A GP A GL L LLLLL+LG G QG G E + R +N +++ ++
Sbjct: 1 MGARASGGPLARAGLLLLLLLLLLLGLLAPGAQGARGRGGAEKNSYRRTVNTFSQSVSSL 60
Query: 61 FKKYEVLA 68
F + V A
Sbjct: 61 FGEDNVRA 68
>gi|239752832 PREDICTED: similar to SET translocation [Homo sapiens]
Length = 302
Score = 35.8 bits (81), Expect = 0.069
Identities = 53/254 (20%), Positives = 94/254 (37%), Gaps = 31/254 (12%)
Query: 165 EGERELQ-AFENIEDEIKLIGYFKSKDSEHYKAFEDAAEEFHPYIPFFATFDSKVAKKLT 223
+GE+E Q A E+I++ I +DSE E + PFF +AK
Sbjct: 46 KGEKEQQEAIEHIDEVQNEIDRLNEQDSEEILKVEQKYNKLRQ--PFFQKRSELIAKIPN 103
Query: 224 LKLNEIDFYEAFMEEPVTIPDKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGI 283
+ F+ P +EE ++++ + + +K + + D+
Sbjct: 104 FGVT------TFVNHPQVSSLLGEEDEEALHYLTKVEVTEFEDIKSGYRIDFYFDENPYF 157
Query: 284 HIVAFAEE------ADPD----------GFEFLETL-----KAVAQDNTENPDLSIIWID 322
F++E DP G + + KA + E P+ W
Sbjct: 158 ENKVFSKEFHLNESGDPSSKSTKIKWKSGKDVTKRSSQTQNKASRKRQHEEPESFFTWFT 217
Query: 323 PDDFPLLVPYWEKTFDIDLSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLE 382
D E+ D+ + V D D DD++D +E E+ LED+ E
Sbjct: 218 -DHSDAGADELEEVIKDDIWPNPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDE 276
Query: 383 GEINTEDDDDDDDD 396
G+ + ++D+DDD+
Sbjct: 277 GDEDEGEEDEDDDE 290
>gi|239747380 PREDICTED: similar to SET translocation [Homo sapiens]
Length = 302
Score = 35.8 bits (81), Expect = 0.069
Identities = 53/254 (20%), Positives = 94/254 (37%), Gaps = 31/254 (12%)
Query: 165 EGERELQ-AFENIEDEIKLIGYFKSKDSEHYKAFEDAAEEFHPYIPFFATFDSKVAKKLT 223
+GE+E Q A E+I++ I +DSE E + PFF +AK
Sbjct: 46 KGEKEQQEAIEHIDEVQNEIDRLNEQDSEEILKVEQKYNKLRQ--PFFQKRSELIAKIPN 103
Query: 224 LKLNEIDFYEAFMEEPVTIPDKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGI 283
+ F+ P +EE ++++ + + +K + + D+
Sbjct: 104 FGVT------TFVNHPQVSSLLGEEDEEALHYLTKVEVTEFEDIKSGYRIDFYFDENPYF 157
Query: 284 HIVAFAEE------ADPD----------GFEFLETL-----KAVAQDNTENPDLSIIWID 322
F++E DP G + + KA + E P+ W
Sbjct: 158 ENKVFSKEFHLNESGDPSSKSTKIKWKSGKDVTKRSSQTQNKASRKRQHEEPESFFTWFT 217
Query: 323 PDDFPLLVPYWEKTFDIDLSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLE 382
D E+ D+ + V D D DD++D +E E+ LED+ E
Sbjct: 218 -DHSDAGADELEEVIKDDIWPNPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDE 276
Query: 383 GEINTEDDDDDDDD 396
G+ + ++D+DDD+
Sbjct: 277 GDEDEGEEDEDDDE 290
>gi|239741205 PREDICTED: similar to SET translocation [Homo sapiens]
Length = 302
Score = 35.8 bits (81), Expect = 0.069
Identities = 53/254 (20%), Positives = 94/254 (37%), Gaps = 31/254 (12%)
Query: 165 EGERELQ-AFENIEDEIKLIGYFKSKDSEHYKAFEDAAEEFHPYIPFFATFDSKVAKKLT 223
+GE+E Q A E+I++ I +DSE E + PFF +AK
Sbjct: 46 KGEKEQQEAIEHIDEVQNEIDRLNEQDSEEILKVEQKYNKLRQ--PFFQKRSELIAKIPN 103
Query: 224 LKLNEIDFYEAFMEEPVTIPDKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGI 283
+ F+ P +EE ++++ + + +K + + D+
Sbjct: 104 FGVT------TFVNHPQVSSLLGEEDEEALHYLTKVEVTEFEDIKSGYRIDFYFDENPYF 157
Query: 284 HIVAFAEE------ADPD----------GFEFLETL-----KAVAQDNTENPDLSIIWID 322
F++E DP G + + KA + E P+ W
Sbjct: 158 ENKVFSKEFHLNESGDPSSKSTKIKWKSGKDVTKRSSQTQNKASRKRQHEEPESFFTWFT 217
Query: 323 PDDFPLLVPYWEKTFDIDLSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLE 382
D E+ D+ + V D D DD++D +E E+ LED+ E
Sbjct: 218 -DHSDAGADELEEVIKDDIWPNPLQYYLVPDMDDEEGGEDDDDDDDDGDEGEEELEDIDE 276
Query: 383 GEINTEDDDDDDDD 396
G+ + ++D+DDD+
Sbjct: 277 GDEDEGEEDEDDDE 290
>gi|21361657 protein disulfide-isomerase A3 precursor [Homo sapiens]
Length = 505
Score = 35.8 bits (81), Expect = 0.069
Identities = 34/128 (26%), Positives = 52/128 (40%), Gaps = 3/128 (2%)
Query: 88 EELILELAAQVLEDKG-VGFGLVDSEKDAAVAKKLGLTEVDSMYVFK-GDEVIEYDGEFS 145
+ L E A KG V VD + K G++ ++ +F+ G+E YDG +
Sbjct: 61 KRLAPEYEAAATRLKGIVPLAKVDCTANTNTCNKYGVSGYPTLKIFRDGEEAGAYDGPRT 120
Query: 146 ADTIVEFLLDVLEDPVELIEGERELQAFENIEDEIKLIGYFKSKDSEHYKAFEDAAEEFH 205
AD IV L + E E + F + +D ++G+F SE + F AA
Sbjct: 121 ADGIVSHLKKQAGPASVPLRTEEEFKKFISDKD-ASIVGFFDDSFSEAHSEFLKAASNLR 179
Query: 206 PYIPFFAT 213
F T
Sbjct: 180 DNYRFAHT 187
>gi|189011568 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 33.9 bits (76), Expect = 0.26
Identities = 29/115 (25%), Positives = 47/115 (40%), Gaps = 27/115 (23%)
Query: 281 DGIHIVAFAEEADPDGFEFLETLKAVAQDNTENPDLSIIWIDPDDFPLLVPYWEKTFDID 340
D ++ FA E+ PDGF +L A++ D P+ +K ++
Sbjct: 1484 DADTLLHFATESTPDGFSCSSSLSALSLDE--------------------PFIQKDVELR 1523
Query: 341 LSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLEGEINTEDDDDDDD 395
+ P V + D+ E + E+ S E E E ++ E + DD DDDD
Sbjct: 1524 IMPP------VQENDN-GNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDD 1571
>gi|189011566 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 33.9 bits (76), Expect = 0.26
Identities = 29/115 (25%), Positives = 47/115 (40%), Gaps = 27/115 (23%)
Query: 281 DGIHIVAFAEEADPDGFEFLETLKAVAQDNTENPDLSIIWIDPDDFPLLVPYWEKTFDID 340
D ++ FA E+ PDGF +L A++ D P+ +K ++
Sbjct: 1484 DADTLLHFATESTPDGFSCSSSLSALSLDE--------------------PFIQKDVELR 1523
Query: 341 LSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLEGEINTEDDDDDDD 395
+ P V + D+ E + E+ S E E E ++ E + DD DDDD
Sbjct: 1524 IMPP------VQENDN-GNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDD 1571
>gi|53759122 adenomatous polyposis coli [Homo sapiens]
Length = 2843
Score = 33.9 bits (76), Expect = 0.26
Identities = 29/115 (25%), Positives = 47/115 (40%), Gaps = 27/115 (23%)
Query: 281 DGIHIVAFAEEADPDGFEFLETLKAVAQDNTENPDLSIIWIDPDDFPLLVPYWEKTFDID 340
D ++ FA E+ PDGF +L A++ D P+ +K ++
Sbjct: 1484 DADTLLHFATESTPDGFSCSSSLSALSLDE--------------------PFIQKDVELR 1523
Query: 341 LSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLEGEINTEDDDDDDD 395
+ P V + D+ E + E+ S E E E ++ E + DD DDDD
Sbjct: 1524 IMPP------VQENDN-GNETESEQPKESNENQEKEAEKTIDSEKDLLDDSDDDD 1571
>gi|158631177 homeodomain leucine zipper protein [Homo sapiens]
Length = 550
Score = 33.9 bits (76), Expect = 0.26
Identities = 32/103 (31%), Positives = 43/103 (41%), Gaps = 20/103 (19%)
Query: 309 DNTENPDLSIIWIDPDDFPLLVPYWEKTFDI-DLSAPQIGVVNVTDADSV--WME----- 360
+ E P L I PD PL YW + + PQ+ + V W +
Sbjct: 447 ERAETPPLPIPPPPPDIQPL-ERYWAAHQQLRETDIPQLSQASRLSTQQVLDWFDSRLPQ 505
Query: 361 -------MDDEEDLPSAEELEDWLEDVLEGEINTEDDDDDDDD 396
+D+EE+ EE E+ ED E E E+DDDDDDD
Sbjct: 506 PAEVVVCLDEEEE----EEEEELPEDDEEEEEEEEEDDDDDDD 544
Score = 33.5 bits (75), Expect = 0.34
Identities = 18/34 (52%), Positives = 21/34 (61%), Gaps = 2/34 (5%)
Query: 363 DEEDLPSAEELEDWLEDVLEGEINTEDDDDDDDD 396
DEE+ EEL + +D E E EDDDDDDDD
Sbjct: 514 DEEEEEEEEELPE--DDEEEEEEEEEDDDDDDDD 545
>gi|119709834 castor homolog 1, zinc finger isoform a [Homo sapiens]
Length = 1759
Score = 33.1 bits (74), Expect = 0.45
Identities = 19/59 (32%), Positives = 29/59 (49%)
Query: 338 DIDLSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLEGEINTEDDDDDDDD 396
D P+ G A + D+EE+L EE + ED + E + ++DDD+DDD
Sbjct: 1653 DAAAPGPREGAAAAAAAAGESSQEDEEEELELPEEEAEDDEDEDDDEDDDDEDDDEDDD 1711
>gi|5031973 protein disulfide isomerase A6 [Homo sapiens]
Length = 440
Score = 32.7 bits (73), Expect = 0.59
Identities = 25/77 (32%), Positives = 41/77 (53%), Gaps = 6/77 (7%)
Query: 95 AAQVLED-KG-VGFGLVDSEKDAAVAKKLGLTEVDSMYVF-KGDEVIEYDGEFSADTIVE 151
A++V E KG V VD+ + +A + G+ ++ +F KG+ ++YDG + IV
Sbjct: 204 ASEVKEQTKGKVKLAAVDATVNQVLASRYGIRGFPTIKIFQKGESPVDYDGGRTRSDIVS 263
Query: 152 FLLDVLED---PVELIE 165
LD+ D P EL+E
Sbjct: 264 RALDLFSDNAPPPELLE 280
>gi|14110378 neighbor of BRCA1 gene 1 [Homo sapiens]
Length = 966
Score = 32.3 bits (72), Expect = 0.77
Identities = 38/157 (24%), Positives = 70/157 (44%), Gaps = 29/157 (18%)
Query: 244 DKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGIHIVAFAEEADPDGFEFL--E 301
D P E+ + +EE K P+SM + + I V AEE D G +F+
Sbjct: 595 DSPLIEKPGLGQIEEENEGAGFKALPDSMVSV-KRKAENIASVEEAEE-DLSGTQFVCET 652
Query: 302 TLKAVAQDNTENPDLSIIWIDPDDFPLLVPYWEKTFDIDLSAPQ--IG-----VVNVTDA 354
++++ D PD P P +K+ + + P+ +G ++++ +
Sbjct: 653 VIRSLTLDAA-----------PDHNP---PCRQKSLQMTFALPEGPLGNEKEEIIHIAEE 698
Query: 355 DSVWMEMDDEEDLPSAEELEDWLEDVLEGEINTEDDD 391
++V E +DEED EE ED L+D ++ + + +D
Sbjct: 699 EAVMEEEEDEED----EEEEDELKDEVQSQSSASSED 731
>gi|14110375 neighbor of BRCA1 gene 1 [Homo sapiens]
Length = 966
Score = 32.3 bits (72), Expect = 0.77
Identities = 38/157 (24%), Positives = 70/157 (44%), Gaps = 29/157 (18%)
Query: 244 DKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGIHIVAFAEEADPDGFEFL--E 301
D P E+ + +EE K P+SM + + I V AEE D G +F+
Sbjct: 595 DSPLIEKPGLGQIEEENEGAGFKALPDSMVSV-KRKAENIASVEEAEE-DLSGTQFVCET 652
Query: 302 TLKAVAQDNTENPDLSIIWIDPDDFPLLVPYWEKTFDIDLSAPQ--IG-----VVNVTDA 354
++++ D PD P P +K+ + + P+ +G ++++ +
Sbjct: 653 VIRSLTLDAA-----------PDHNP---PCRQKSLQMTFALPEGPLGNEKEEIIHIAEE 698
Query: 355 DSVWMEMDDEEDLPSAEELEDWLEDVLEGEINTEDDD 391
++V E +DEED EE ED L+D ++ + + +D
Sbjct: 699 EAVMEEEEDEED----EEEEDELKDEVQSQSSASSED 731
>gi|14110381 neighbor of BRCA1 gene 1 [Homo sapiens]
Length = 966
Score = 32.3 bits (72), Expect = 0.77
Identities = 38/157 (24%), Positives = 70/157 (44%), Gaps = 29/157 (18%)
Query: 244 DKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGIHIVAFAEEADPDGFEFL--E 301
D P E+ + +EE K P+SM + + I V AEE D G +F+
Sbjct: 595 DSPLIEKPGLGQIEEENEGAGFKALPDSMVSV-KRKAENIASVEEAEE-DLSGTQFVCET 652
Query: 302 TLKAVAQDNTENPDLSIIWIDPDDFPLLVPYWEKTFDIDLSAPQ--IG-----VVNVTDA 354
++++ D PD P P +K+ + + P+ +G ++++ +
Sbjct: 653 VIRSLTLDAA-----------PDHNP---PCRQKSLQMTFALPEGPLGNEKEEIIHIAEE 698
Query: 355 DSVWMEMDDEEDLPSAEELEDWLEDVLEGEINTEDDD 391
++V E +DEED EE ED L+D ++ + + +D
Sbjct: 699 EAVMEEEEDEED----EEEEDELKDEVQSQSSASSED 731
>gi|210032580 SET domain containing 1B [Homo sapiens]
Length = 1923
Score = 32.0 bits (71), Expect = 1.0
Identities = 15/37 (40%), Positives = 21/37 (56%)
Query: 360 EMDDEEDLPSAEELEDWLEDVLEGEINTEDDDDDDDD 396
E D++E L +E + E+ E E +DDDDD DD
Sbjct: 1034 EEDEKESLSEEQESTEEEEEAEEEEEEEDDDDDDSDD 1070
>gi|24308127 DnaJ (Hsp40) homolog, subfamily C, member 10 [Homo
sapiens]
Length = 793
Score = 31.6 bits (70), Expect = 1.3
Identities = 15/56 (26%), Positives = 26/56 (46%)
Query: 106 FGLVDSEKDAAVAKKLGLTEVDSMYVFKGDEVIEYDGEFSADTIVEFLLDVLEDPV 161
FG +D + + + VF + EY+G SA+ I+EF+ D++ V
Sbjct: 503 FGTLDCTVHEGLCNMYNIQAYPTTVVFNQSNIHEYEGHHSAEQILEFIEDLMNPSV 558
>gi|48762709 SAM domain, SH3 domain and nuclear localization
signals, 1 [Homo sapiens]
Length = 373
Score = 31.6 bits (70), Expect = 1.3
Identities = 22/77 (28%), Positives = 37/77 (48%), Gaps = 11/77 (14%)
Query: 244 DKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGIHIVAFAEEADPDGFEFLETL 303
D + EE ++ +RRS +K K T ++ ++ IH+ + +G+E LE L
Sbjct: 220 DVISEEEAAPKKIKANRRSNSKKSK------TLQEFLERIHLQEYTSTLLLNGYETLEDL 273
Query: 304 KAVAQD-----NTENPD 315
K + + N ENPD
Sbjct: 274 KDIKESHLIELNIENPD 290
>gi|94681063 bromodomain adjacent to zinc finger domain, 2B [Homo
sapiens]
Length = 2168
Score = 31.6 bits (70), Expect = 1.3
Identities = 12/33 (36%), Positives = 23/33 (69%)
Query: 364 EEDLPSAEELEDWLEDVLEGEINTEDDDDDDDD 396
+ D+PS+++ ED ED E + +++DD+DD+
Sbjct: 595 DSDIPSSKDSEDSNEDEEEDDEEEDEEDDEDDE 627
>gi|42516574 tripartite motif-containing 41 isoform 2 [Homo sapiens]
Length = 518
Score = 31.6 bits (70), Expect = 1.3
Identities = 15/41 (36%), Positives = 26/41 (63%), Gaps = 6/41 (14%)
Query: 355 DSVWMEMDDEEDLPSAEELEDWLEDVLEGEINTEDDDDDDD 395
D VW E D+EEDL + +L D+ E ++ ED++D+++
Sbjct: 121 DYVWEEEDEEEDL------DYYLGDMEEEDLRGEDEEDEEE 155
>gi|42516572 tripartite motif-containing 41 isoform 1 [Homo sapiens]
Length = 630
Score = 31.6 bits (70), Expect = 1.3
Identities = 15/41 (36%), Positives = 26/41 (63%), Gaps = 6/41 (14%)
Query: 355 DSVWMEMDDEEDLPSAEELEDWLEDVLEGEINTEDDDDDDD 395
D VW E D+EEDL + +L D+ E ++ ED++D+++
Sbjct: 121 DYVWEEEDEEEDL------DYYLGDMEEEDLRGEDEEDEEE 155
>gi|75677335 digestive-organ expansion factor homolog [Homo sapiens]
Length = 756
Score = 31.6 bits (70), Expect = 1.3
Identities = 35/144 (24%), Positives = 57/144 (39%), Gaps = 16/144 (11%)
Query: 181 KLIGYFKSKDSEHYKAFEDAAEEFHPYIPFFATFDSKVAKKLTLKLNEIDFYEAFMEEPV 240
+L+ K +H + F EE PF+ K AK +L+E
Sbjct: 11 QLLNTLTKKQKKHLRDF---GEEH----PFYDRVSRKEAKPQICQLSE---------SSD 54
Query: 241 TIPDKPNSEEEIVNFVEEHRRSTLRKLKPESMYETWEDDMDGIHIVAFAEEADPDGFEFL 300
+ + +SE E HR K E E E++ + IV AE D DG +
Sbjct: 55 SSDSESDSESEPQQVSGYHRLLATLKNVSEEEEEDEEEEEEEDSIVDDAEMNDEDGGSDV 114
Query: 301 ETLKAVAQDNTENPDLSIIWIDPD 324
+ +A ++TE+P+ + DP+
Sbjct: 115 SVEEEMAAESTESPENVALSADPE 138
>gi|24497618 ATPase family, AAA domain containing 2 [Homo sapiens]
Length = 1390
Score = 31.2 bits (69), Expect = 1.7
Identities = 18/36 (50%), Positives = 23/36 (63%), Gaps = 1/36 (2%)
Query: 362 DDEEDLPSAEELEDWL-EDVLEGEINTEDDDDDDDD 396
+ E + S+EE ED ED E E + +DDDDDDDD
Sbjct: 237 NQEGSVESSEEGEDQEHEDDGEDEDDEDDDDDDDDD 272
>gi|61676188 HECT, UBA and WWE domain containing 1 [Homo sapiens]
Length = 4374
Score = 31.2 bits (69), Expect = 1.7
Identities = 16/44 (36%), Positives = 23/44 (52%)
Query: 353 DADSVWMEMDDEEDLPSAEELEDWLEDVLEGEINTEDDDDDDDD 396
+ DS D+++ EE E+ ED E + E D+DDDDD
Sbjct: 2418 EEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDEGEEGDEDDDDD 2461
Score = 29.6 bits (65), Expect = 5.0
Identities = 19/56 (33%), Positives = 28/56 (50%), Gaps = 1/56 (1%)
Query: 341 LSAPQIGVVNVTDADSVWMEMDDEEDLPSAEELEDWLEDVLEGEINTEDDDDDDDD 396
L A + +N+ D + E EED + E ED +D E E E+DD +DD+
Sbjct: 2396 LQANREDSMNILDPEDE-EEHTQEEDSSGSNEDEDDSQDEEEEEEEDEEDDQEDDE 2450
Score = 29.3 bits (64), Expect = 6.5
Identities = 15/37 (40%), Positives = 21/37 (56%), Gaps = 2/37 (5%)
Query: 360 EMDDEEDLPSAEELEDWLEDVLEGEINTEDDDDDDDD 396
+ DEE+ +E +D +D EGE EDDDDD +
Sbjct: 2430 DSQDEEEEEEEDEEDDQEDD--EGEEGDEDDDDDGSE 2464
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.314 0.137 0.391
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 15,478,710
Number of Sequences: 37866
Number of extensions: 719301
Number of successful extensions: 3062
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 37
Number of HSP's successfully gapped in prelim test: 42
Number of HSP's that attempted gapping in prelim test: 2668
Number of HSP's gapped (non-prelim): 308
length of query: 396
length of database: 18,247,518
effective HSP length: 104
effective length of query: 292
effective length of database: 14,309,454
effective search space: 4178360568
effective search space used: 4178360568
T: 11
A: 40
X1: 16 ( 7.2 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.9 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.