Search of human proteins with 225703081

Search of human proteins with 225703081

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|225703081 membrane bound O-acyltransferase domain containing
7 isoform 2 [Homo sapiens]
         (399 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|225703081 membrane bound O-acyltransferase domain containing ...   842   0.0  
gi|225703033 membrane bound O-acyltransferase domain containing ...   842   0.0  
gi|225703079 membrane bound O-acyltransferase domain containing ...   754   0.0  
gi|225703037 membrane bound O-acyltransferase domain containing ...   488   e-138
gi|40548387 O-acyltransferase (membrane bound) domain containing...   110   2e-24
gi|122937404 membrane bound O-acyltransferase domain containing ...   101   1e-21
gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo sapi...    71   2e-12
gi|45439337 porcupine isoform E [Homo sapiens]                         44   3e-04
gi|45439333 porcupine isoform C [Homo sapiens]                         44   3e-04
gi|45439329 porcupine isoform A [Homo sapiens]                         44   3e-04
gi|189571629 membrane bound O-acyltransferase domain containing ...    44   3e-04
gi|45439335 porcupine isoform D [Homo sapiens]                         41   0.002
gi|45439331 porcupine isoform B [Homo sapiens]                         41   0.002
gi|126507091 LATS, large tumor suppressor, homolog 2 [Homo sapiens]    30   2.9  
gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo s...    30   3.8  
gi|223890259 midline 2 isoform 2 [Homo sapiens]                        29   6.6  
gi|223890257 midline 2 isoform 1 [Homo sapiens]                        29   6.6  
gi|24430215 interleukin 10 receptor, beta precursor [Homo sapiens]     29   6.6  
gi|239757081 PREDICTED: hypothetical protein LOC100127987 [Homo ...    29   6.6  
gi|169213239 PREDICTED: hypothetical protein LOC100127987 [Homo ...    29   6.6  
gi|169212748 PREDICTED: hypothetical protein LOC100127987 [Homo ...    29   6.6  
gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Ho...    29   8.6  
gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Ho...    29   8.6  
gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Ho...    29   8.6  
gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ...    29   8.6  
gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo ...    29   8.6  
gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo ...    29   8.6  
gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo ...    29   8.6  
gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo ...    29   8.6  
gi|56090548 insulin-like growth factor binding protein-like 1 [H...    29   8.6  

>gi|225703081 membrane bound O-acyltransferase domain containing 7
           isoform 2 [Homo sapiens]
          Length = 399

 Score =  842 bits (2176), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MGSSRCGPGAHPVHLWPPHFAFSGHHPRDLGPHSGPALLVSLASEVQDLHLAQRKEMASG 60
           MGSSRCGPGAHPVHLWPPHFAFSGHHPRDLGPHSGPALLVSLASEVQDLHLAQRKEMASG
Sbjct: 1   MGSSRCGPGAHPVHLWPPHFAFSGHHPRDLGPHSGPALLVSLASEVQDLHLAQRKEMASG 60

Query: 61  FSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLR 120
           FSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLR
Sbjct: 61  FSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLR 120

Query: 121 RAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYVAWIAAE 180
           RAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYVAWIAAE
Sbjct: 121 RAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYVAWIAAE 180

Query: 181 CGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRV 240
           CGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRV
Sbjct: 181 CGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRV 240

Query: 241 RDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCL 300
           RDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCL
Sbjct: 241 RDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCL 300

Query: 301 AAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCI 360
           AAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCI
Sbjct: 301 AAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCI 360

Query: 361 HFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLREE 399
           HFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLREE
Sbjct: 361 HFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLREE 399


>gi|225703033 membrane bound O-acyltransferase domain containing 7
           isoform 2 [Homo sapiens]
          Length = 399

 Score =  842 bits (2176), Expect = 0.0
 Identities = 399/399 (100%), Positives = 399/399 (100%)

Query: 1   MGSSRCGPGAHPVHLWPPHFAFSGHHPRDLGPHSGPALLVSLASEVQDLHLAQRKEMASG 60
           MGSSRCGPGAHPVHLWPPHFAFSGHHPRDLGPHSGPALLVSLASEVQDLHLAQRKEMASG
Sbjct: 1   MGSSRCGPGAHPVHLWPPHFAFSGHHPRDLGPHSGPALLVSLASEVQDLHLAQRKEMASG 60

Query: 61  FSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLR 120
           FSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLR
Sbjct: 61  FSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLR 120

Query: 121 RAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYVAWIAAE 180
           RAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYVAWIAAE
Sbjct: 121 RAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYVAWIAAE 180

Query: 181 CGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRV 240
           CGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRV
Sbjct: 181 CGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRV 240

Query: 241 RDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCL 300
           RDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCL
Sbjct: 241 RDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCL 300

Query: 301 AAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCI 360
           AAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCI
Sbjct: 301 AAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCI 360

Query: 361 HFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLREE 399
           HFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLREE
Sbjct: 361 HFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLREE 399


>gi|225703079 membrane bound O-acyltransferase domain containing 7
           isoform 1 [Homo sapiens]
          Length = 472

 Score =  754 bits (1946), Expect = 0.0
 Identities = 361/361 (100%), Positives = 361/361 (100%)

Query: 39  LVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYR 98
           LVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYR
Sbjct: 112 LVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYR 171

Query: 99  TYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARL 158
           TYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARL
Sbjct: 172 TYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARL 231

Query: 159 FYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAAS 218
           FYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAAS
Sbjct: 232 FYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAAS 291

Query: 219 LEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLL 278
           LEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLL
Sbjct: 292 LEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLL 351

Query: 279 SAYWHGLHPGYYLSFLTIPLCLAAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMC 338
           SAYWHGLHPGYYLSFLTIPLCLAAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMC
Sbjct: 352 SAYWHGLHPGYYLSFLTIPLCLAAEGRLESALRGRLSPGGQKAWDWVHWFLKMRAYDYMC 411

Query: 339 MGFVLLSLADTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLRE 398
           MGFVLLSLADTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLRE
Sbjct: 412 MGFVLLSLADTLRYWASIYFCIHFLALAALGLGLALGGGSPSRRKAASQPTSLAPEKLRE 471

Query: 399 E 399
           E
Sbjct: 472 E 472


>gi|225703037 membrane bound O-acyltransferase domain containing 7
           isoform 3 [Homo sapiens]
          Length = 344

 Score =  488 bits (1255), Expect = e-138
 Identities = 233/233 (100%), Positives = 233/233 (100%)

Query: 39  LVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYR 98
           LVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYR
Sbjct: 112 LVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGPFFRYR 171

Query: 99  TYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARL 158
           TYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARL
Sbjct: 172 TYLDWLEQPFPGAVPSLRPLLRRAWPAPLFGLLFLLSSHLFPLEAVREDAFYARPLPARL 231

Query: 159 FYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAAS 218
           FYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAAS
Sbjct: 232 FYMIPVFFAFRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAAS 291

Query: 219 LEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLR 271
           LEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLR
Sbjct: 292 LEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLR 344


>gi|40548387 O-acyltransferase (membrane bound) domain containing 2
           [Homo sapiens]
          Length = 520

 Score =  110 bits (276), Expect = 2e-24
 Identities = 104/393 (26%), Positives = 166/393 (42%), Gaps = 62/393 (15%)

Query: 34  SGPALLV-----SLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVG 88
           SGP +++     SLA E+ D    + +E+ S         +    PSL+E LSY+  ++G
Sbjct: 131 SGPMMIITQKITSLACEIHDGMFRKDEELTSSQRDLAVRRM----PSLLEYLSYNCNFMG 186

Query: 89  IMTGPFFRYRTYLDWLEQPF-----PGAVPSLRPLLRRAWPAPL-----------FGLLF 132
           I+ GP   Y+ Y+ ++E         G          R  P+P              LLF
Sbjct: 187 ILAGPLCSYKDYITFIEGRSYHITQSGENGKEETQYERTEPSPNTAVVQKLLVCGLSLLF 246

Query: 133 LLS-SHLFPLEAVREDAFYARPL-PARLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFG- 189
            L+     P+E   ++ F A    P ++ Y+     A R ++Y AW  A+    AAGFG 
Sbjct: 247 HLTICTTLPVEYNIDEHFQATASWPTKIIYLYISLLAARPKYYFAWTLADAINNAAGFGF 306

Query: 190 -AYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVRDGMRYWN 248
             Y     AR                        ++ I N+     +     +  +  WN
Sbjct: 307 RGYDENGAAR------------------------WDLISNLRIQQIEMSTSFKMFLDNWN 342

Query: 249 MTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT-IPLCLAAEGRLE 307
           +    WL +  Y+    R+    +  T +LSA WHG++PGYYL+FLT + + LAA     
Sbjct: 343 IQTALWLKRVCYE----RTSFSPTIQTFILSAIWHGVYPGYYLTFLTGVLMTLAARAMRN 398

Query: 308 SALRGRLSPGGQKA-WDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCIHFLALA 366
           +     + P   K  +D + W +   A  Y  + FVLLS+  +L +++S Y+C+H L + 
Sbjct: 399 NFRHYFIEPSQLKLFYDVITWIVTQVAISYTVVPFVLLSIKPSLTFYSSWYYCLHILGIL 458

Query: 367 ALGLGLALGGGSPSRRKAASQPTSLAPEKLREE 399
            L   L L      RRK   +   L+  K  +E
Sbjct: 459 VL---LLLPVKKTQRRKNTHENIQLSQSKKFDE 488


>gi|122937404 membrane bound O-acyltransferase domain containing 1
           [Homo sapiens]
          Length = 495

 Score =  101 bits (252), Expect = 1e-21
 Identities = 94/358 (26%), Positives = 156/358 (43%), Gaps = 57/358 (15%)

Query: 34  SGPALLVS-----LASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVG 88
           SGP ++V+     LA +V D  L +R E  S       + + P   S +E LSY   ++ 
Sbjct: 139 SGPLMIVTQKITTLAFQVHD-GLGRRAEDLSAEQHRLAIKVKP---SFLEYLSYLLNFMS 194

Query: 89  IMTGPFFRYRTYL---------------DWLEQPFPGAVPSLRP---LLRRAWPAPLFGL 130
           ++ GP   ++ Y+               +W  + F  ++P   P   ++ +     +  L
Sbjct: 195 VIAGPCNNFKDYIAFIEGKHIHMKLLEVNWKRKGFH-SLPEPSPTGAVIHKLGITLVSLL 253

Query: 131 LFLLSSHLFPLEAVREDAF-YARPLPARLFYMIPVFFAFRMRFYVAWIAAECGCIAAGFG 189
           LFL  +  FP+  + +D F +    PARL Y+  V  A + ++Y AW  A+    AAGFG
Sbjct: 254 LFLTLTKTFPVTCLVDDWFVHKASFPARLCYLYVVMQASKPKYYFAWTLADAVNNAAGFG 313

Query: 190 AYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVRDGMRYWNM 249
              V                           + ++ + N++ +  +     +  +  WN+
Sbjct: 314 FSGVDKNGN----------------------FCWDLLSNLNIWKIETATSFKMYLENWNI 351

Query: 250 TVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT-IPLCLAAEGRLES 308
               WL    Y+  P    VL    T +LSA WHG++PGYY +FLT I + LAA     +
Sbjct: 352 QTATWLKCVCYQRVPWYPTVL----TFILSALWHGVYPGYYFTFLTGILVTLAARAVRNN 407

Query: 309 ALRGRLSPGGQKA-WDWVHWFLKMRAYDYMCMGFVLLSLADTLRYWASIYFCIHFLAL 365
                LS    KA +D   W +   A  Y    FV+L++  T+  + S+YF +H ++L
Sbjct: 408 YRHYFLSSRALKAVYDAGTWAVTQLAVSYTVAPFVMLAVEPTISLYKSMYFYLHIISL 465


>gi|42542394 lysophosphatidylcholine acyltransferase 3 [Homo
           sapiens]
          Length = 487

 Score = 71.2 bits (173), Expect = 2e-12
 Identities = 79/315 (25%), Positives = 122/315 (38%), Gaps = 48/315 (15%)

Query: 73  VPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQ---PFPGAVP-SLRPLLRRAWPAPLF 128
           VPSL+E   +SY Y   + GP F    Y+  ++      PG +P S+ P L+R     LF
Sbjct: 181 VPSLLEVAGFSYFYGAFLVGPQFSMNHYMKLVQGELIDIPGKIPNSIIPALKRL-SLGLF 239

Query: 129 GLL--FLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMRFYV-AWIAAECGCIA 185
            L+   LLS H+     + ED +   P   R  YM+ ++  F +  YV  W+  E  CI 
Sbjct: 240 YLVGYTLLSPHITEDYLLTED-YDNHPFWFRCMYML-IWGKFVLYKYVTCWLVTEGVCIL 297

Query: 186 AGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVRDGMR 245
            G G      K +A                       ++   N+  +  +   R    + 
Sbjct: 298 TGLGFNGFEEKGKA----------------------KWDACANMKVWLFETNPRFTGTIA 335

Query: 246 YWNMTVQWWLAQYIYKSAP-ARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLAAEG 304
            +N+    W+A+YI+K      +  L    ++L  A WHGLH GY + F    L +  E 
Sbjct: 336 SFNINTNAWVARYIFKRLKFLGNKELSQGLSLLFLALWHGLHSGYLVCFQMEFLIVIVER 395

Query: 305 RLESALRGR-----------LSPGGQKAWDWVHWFLKMRAYDYMCMGFVLLSLADTLRYW 353
           +    ++             L P        +HW        Y    F L +    L+ +
Sbjct: 396 QAARLIQESPTLSKLAAITVLQPFYYLVQQTIHWLF----MGYSMTAFCLFTWDKWLKVY 451

Query: 354 ASIYFCIHFLALAAL 368
            SIYF  H   L+ L
Sbjct: 452 KSIYFLGHIFFLSLL 466


>gi|45439337 porcupine isoform E [Homo sapiens]
          Length = 379

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 63/254 (24%), Positives = 94/254 (37%), Gaps = 45/254 (17%)

Query: 68  GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 127
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 73  GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 128

Query: 128 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRM-RFYVAWIAAECGCIAA 186
             L  +LS+ + P                   Y+ P F      R    W+ A    ++ 
Sbjct: 129 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRKWLRAYESAVSF 169

Query: 187 GFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVR 241
            F  Y V     A    AG G T         E+   LE+D    + ++       V V 
Sbjct: 170 HFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPRSMVEV- 219

Query: 242 DGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLA 301
             +  WN+ + +WL  Y++K+A           T   SA  H    G+      + L LA
Sbjct: 220 --VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAAVLLSLA 273

Query: 302 AEGRLESALRGRLS 315
               +E  LR RL+
Sbjct: 274 FITYVEHVLRKRLA 287


>gi|45439333 porcupine isoform C [Homo sapiens]
          Length = 455

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 64/259 (24%), Positives = 95/259 (36%), Gaps = 50/259 (19%)

Query: 68  GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 127
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199

Query: 128 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAF------RMRFYVAWIAAEC 181
             L  +LS+ + P                   Y+ P F         R    V W+ A  
Sbjct: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRKGTMVRWLRAYE 240

Query: 182 GCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDF 236
             ++  F  Y V     A    AG G T         E+   LE+D    + ++      
Sbjct: 241 SAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPRS 291

Query: 237 CVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTI 296
            V V   +  WN+ + +WL  Y++K+A           T   SA  H    G+      +
Sbjct: 292 MVEV---VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAAV 344

Query: 297 PLCLAAEGRLESALRGRLS 315
            L LA    +E  LR RL+
Sbjct: 345 LLSLAFITYVEHVLRKRLA 363


>gi|45439329 porcupine isoform A [Homo sapiens]
          Length = 450

 Score = 43.9 bits (102), Expect = 3e-04
 Identities = 63/254 (24%), Positives = 94/254 (37%), Gaps = 45/254 (17%)

Query: 68  GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 127
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199

Query: 128 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRM-RFYVAWIAAECGCIAA 186
             L  +LS+ + P                   Y+ P F      R    W+ A    ++ 
Sbjct: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRKWLRAYESAVSF 240

Query: 187 GFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTDFCVRVR 241
            F  Y V     A    AG G T         E+   LE+D    + ++       V V 
Sbjct: 241 HFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPRSMVEV- 290

Query: 242 DGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLTIPLCLA 301
             +  WN+ + +WL  Y++K+A           T   SA  H    G+      + L LA
Sbjct: 291 --VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAAVLLSLA 344

Query: 302 AEGRLESALRGRLS 315
               +E  LR RL+
Sbjct: 345 FITYVEHVLRKRLA 358


>gi|189571629 membrane bound O-acyltransferase domain containing 4
           [Homo sapiens]
          Length = 435

 Score = 43.5 bits (101), Expect = 3e-04
 Identities = 36/141 (25%), Positives = 60/141 (42%), Gaps = 28/141 (19%)

Query: 168 FRMRFYVAWIAAECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSPEKAASLEYDYETIR 227
           F++ +Y  WI  +    AAGFG             P L   P          E  Y  + 
Sbjct: 251 FKLTYYSHWILDDSLLHAAGFG-------------PELGQSPG---------EEGY--VP 286

Query: 228 NIDCYSTDFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHP 287
           + D ++ +   R+    R WN +   WL + +++ +  R++ L    T   SA+WHGLHP
Sbjct: 287 DADIWTLERTHRISVFSRKWNQSTARWLRRLVFQHS--RAWPLLQ--TFAFSAWWHGLHP 342

Query: 288 GYYLSFLTIPLCLAAEGRLES 308
           G    F+   + + A+  + S
Sbjct: 343 GQVFGFVCWAVMVEADYLIHS 363


>gi|45439335 porcupine isoform D [Homo sapiens]
          Length = 461

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 66/261 (25%), Positives = 98/261 (37%), Gaps = 48/261 (18%)

Query: 68  GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 127
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199

Query: 128 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFRMR--------FYVAWIAA 179
             L  +LS+ + P         Y  P      Y IP+     +R          V W+ A
Sbjct: 200 ALLCLVLSTCVGP---------YLFP------YFIPLNGDRLLRNKKRKARGTMVRWLRA 244

Query: 180 ECGCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYST 234
               ++  F  Y V     A    AG G T         E+   LE+D    + ++    
Sbjct: 245 YESAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELP 295

Query: 235 DFCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFL 294
              V V   +  WN+ + +WL  Y++K+A           T   SA  H    G+     
Sbjct: 296 RSMVEV---VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLA 348

Query: 295 TIPLCLAAEGRLESALRGRLS 315
            + L LA    +E  LR RL+
Sbjct: 349 AVLLSLAFITYVEHVLRKRLA 369


>gi|45439331 porcupine isoform B [Homo sapiens]
          Length = 456

 Score = 40.8 bits (94), Expect = 0.002
 Identities = 62/260 (23%), Positives = 94/260 (36%), Gaps = 51/260 (19%)

Query: 68  GLLPDVPSLMETLSYSYCYVGIMTGPFFRYRTYLDWLEQPFPGAVPSLRPLLRRAWPAPL 127
           G +  VPS +E + Y Y    I+ GP+  + +YL    Q   G   S R L + A    L
Sbjct: 144 GEVGTVPSPVEFMGYLYFVGTIVFGPWISFHSYL----QAVQGRPLSCRWLQKVARSLAL 199

Query: 128 FGLLFLLSSHLFPLEAVREDAFYARPLPARLFYMIPVFFAFR-------MRFYVAWIAAE 180
             L  +LS+ + P                   Y+ P F            +    W+ A 
Sbjct: 200 ALLCLVLSTCVGP-------------------YLFPYFIPLNGDRLLRNKKRKARWLRAY 240

Query: 181 CGCIAAGFGAYPV-----AAKARAGGGPTLQCPPPSSPEKAASLEYDYETIRNIDCYSTD 235
              ++  F  Y V     A    AG G T         E+   LE+D    + ++     
Sbjct: 241 ESAVSFHFSNYFVGFLSEATATLAGAGFT---------EEKDHLEWDLTVSKPLNVELPR 291

Query: 236 FCVRVRDGMRYWNMTVQWWLAQYIYKSAPARSYVLRSAWTMLLSAYWHGLHPGYYLSFLT 295
             V V   +  WN+ + +WL  Y++K+A           T   SA  H    G+      
Sbjct: 292 SMVEV---VTSWNLPMSYWLNNYVFKNALRLGTFSAVLVTYAASALLH----GFSFHLAA 344

Query: 296 IPLCLAAEGRLESALRGRLS 315
           + L LA    +E  LR RL+
Sbjct: 345 VLLSLAFITYVEHVLRKRLA 364


>gi|126507091 LATS, large tumor suppressor, homolog 2 [Homo sapiens]
          Length = 1088

 Score = 30.4 bits (67), Expect = 2.9
 Identities = 15/44 (34%), Positives = 26/44 (59%), Gaps = 7/44 (15%)

Query: 187 GFGAYPVAAKARAGGGPTLQCPPPSSPE----KAASLEYDYETI 226
           G GA+P+  +    GGP  +CPPP  P+    ++ S +YD +++
Sbjct: 496 GAGAFPLDVEY---GGPDRRCPPPPYPKHLLLRSKSEQYDLDSL 536


>gi|25777671 protein phosphatase 1, regulatory subunit 10 [Homo
           sapiens]
          Length = 940

 Score = 30.0 bits (66), Expect = 3.8
 Identities = 14/34 (41%), Positives = 15/34 (44%)

Query: 2   GSSRCGPGAHPVHLWPPHFAFSGHHPRDLGPHSG 35
           G S  G G H  H  P H    GH P D+  H G
Sbjct: 836 GGSMGGSGGHRPHEGPGHGGPHGHRPHDVPGHRG 869


>gi|223890259 midline 2 isoform 2 [Homo sapiens]
          Length = 705

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 15/69 (21%), Positives = 28/69 (40%), Gaps = 3/69 (4%)

Query: 214 EKAASLEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTV---QWWLAQYIYKSAPARSYVL 270
           E +    +  E      CY     + +  G  YW + +    W+     YKSAP   ++ 
Sbjct: 530 ESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIG 589

Query: 271 RSAWTMLLS 279
           ++A + + S
Sbjct: 590 KNASSWVFS 598


>gi|223890257 midline 2 isoform 1 [Homo sapiens]
          Length = 735

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 15/69 (21%), Positives = 28/69 (40%), Gaps = 3/69 (4%)

Query: 214 EKAASLEYDYETIRNIDCYSTDFCVRVRDGMRYWNMTV---QWWLAQYIYKSAPARSYVL 270
           E +    +  E      CY     + +  G  YW + +    W+     YKSAP   ++ 
Sbjct: 560 ESSLKKSHTPERFSGTGCYGAAGNIFIDSGCHYWEVVMGSSTWYAIGIAYKSAPKNEWIG 619

Query: 271 RSAWTMLLS 279
           ++A + + S
Sbjct: 620 KNASSWVFS 628


>gi|24430215 interleukin 10 receptor, beta precursor [Homo sapiens]
          Length = 325

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 12/34 (35%), Positives = 23/34 (67%), Gaps = 1/34 (2%)

Query: 220 EYDYETIRNIDCYSTDFCVRVRDGMRYWNMTVQW 253
           +YD+E +RN++ ++T +CV+VR  +   N   +W
Sbjct: 172 QYDFEVLRNLEPWTT-YCVQVRGFLPDRNKAGEW 204


>gi|239757081 PREDICTED: hypothetical protein LOC100127987 [Homo
           sapiens]
          Length = 755

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 15/35 (42%), Positives = 17/35 (48%)

Query: 179 AECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSP 213
           AEC    AG    P+AA+ R    P   C P SSP
Sbjct: 349 AECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSP 383


>gi|169213239 PREDICTED: hypothetical protein LOC100127987 [Homo
           sapiens]
          Length = 755

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 15/35 (42%), Positives = 17/35 (48%)

Query: 179 AECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSP 213
           AEC    AG    P+AA+ R    P   C P SSP
Sbjct: 349 AECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSP 383


>gi|169212748 PREDICTED: hypothetical protein LOC100127987 [Homo
           sapiens]
          Length = 755

 Score = 29.3 bits (64), Expect = 6.6
 Identities = 15/35 (42%), Positives = 17/35 (48%)

Query: 179 AECGCIAAGFGAYPVAAKARAGGGPTLQCPPPSSP 213
           AEC    AG    P+AA+ R    P   C P SSP
Sbjct: 349 AECAMPGAGGTHSPIAARGRYRSHPKGNCSPGSSP 383


>gi|169167211 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
           sapiens]
          Length = 2139

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 13/23 (56%), Positives = 16/23 (69%)

Query: 28  RDLGPHSGPALLVSLASEVQDLH 50
           R LGPHS  +++V LA  VQD H
Sbjct: 658 RHLGPHSPQSVMVQLAFHVQDDH 680


>gi|169166904 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
           sapiens]
          Length = 2139

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 13/23 (56%), Positives = 16/23 (69%)

Query: 28  RDLGPHSGPALLVSLASEVQDLH 50
           R LGPHS  +++V LA  VQD H
Sbjct: 658 RHLGPHSPQSVMVQLAFHVQDDH 680


>gi|169166334 PREDICTED: FRAS1 related extracellular matrix 3 [Homo
           sapiens]
          Length = 2139

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 13/23 (56%), Positives = 16/23 (69%)

Query: 28  RDLGPHSGPALLVSLASEVQDLH 50
           R LGPHS  +++V LA  VQD H
Sbjct: 658 RHLGPHSPQSVMVQLAFHVQDDH 680


>gi|38679977 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
            sapiens]
          Length = 2346

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 21/64 (32%), Positives = 29/64 (45%)

Query: 34   SGPALLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGP 93
            SG  L +SL  EV D   AQ    A G  +GP  G+L + P + + L  S  +     G 
Sbjct: 1536 SGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGT 1595

Query: 94   FFRY 97
             + Y
Sbjct: 1596 TYIY 1599


>gi|38679974 acetyl-Coenzyme A carboxylase alpha isoform 4 [Homo
            sapiens]
          Length = 2268

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 21/64 (32%), Positives = 29/64 (45%)

Query: 34   SGPALLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGP 93
            SG  L +SL  EV D   AQ    A G  +GP  G+L + P + + L  S  +     G 
Sbjct: 1458 SGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGT 1517

Query: 94   FFRY 97
             + Y
Sbjct: 1518 TYIY 1521


>gi|38679971 acetyl-Coenzyme A carboxylase alpha isoform 3 [Homo
            sapiens]
          Length = 2288

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 21/64 (32%), Positives = 29/64 (45%)

Query: 34   SGPALLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGP 93
            SG  L +SL  EV D   AQ    A G  +GP  G+L + P + + L  S  +     G 
Sbjct: 1478 SGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGT 1537

Query: 94   FFRY 97
             + Y
Sbjct: 1538 TYIY 1541


>gi|38679967 acetyl-Coenzyme A carboxylase alpha isoform 2 [Homo
            sapiens]
          Length = 2346

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 21/64 (32%), Positives = 29/64 (45%)

Query: 34   SGPALLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGP 93
            SG  L +SL  EV D   AQ    A G  +GP  G+L + P + + L  S  +     G 
Sbjct: 1536 SGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGT 1595

Query: 94   FFRY 97
             + Y
Sbjct: 1596 TYIY 1599


>gi|38679960 acetyl-Coenzyme A carboxylase alpha isoform 1 [Homo
            sapiens]
          Length = 2383

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 21/64 (32%), Positives = 29/64 (45%)

Query: 34   SGPALLVSLASEVQDLHLAQRKEMASGFSKGPTLGLLPDVPSLMETLSYSYCYVGIMTGP 93
            SG  L +SL  EV D   AQ    A G  +GP  G+L + P + + L  S  +     G 
Sbjct: 1573 SGYYLDISLYKEVTDSRTAQIMFQAYGDKQGPLHGMLINTPYVTKDLLQSKRFQAQSLGT 1632

Query: 94   FFRY 97
             + Y
Sbjct: 1633 TYIY 1636


>gi|56090548 insulin-like growth factor binding protein-like 1 [Homo
           sapiens]
          Length = 278

 Score = 28.9 bits (63), Expect = 8.6
 Identities = 15/30 (50%), Positives = 16/30 (53%), Gaps = 2/30 (6%)

Query: 180 ECGCIAAGFGAYPVAAKARAGG--GPTLQC 207
           ECGC A   GA   +   RAGG  GP L C
Sbjct: 62  ECGCCARCLGAEGASCGGRAGGRCGPGLVC 91


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.326    0.140    0.474 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 18,115,270
Number of Sequences: 37866
Number of extensions: 873544
Number of successful extensions: 3307
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 20
Number of HSP's successfully gapped in prelim test: 10
Number of HSP's that attempted gapping in prelim test: 3261
Number of HSP's gapped (non-prelim): 39
length of query: 399
length of database: 18,247,518
effective HSP length: 104
effective length of query: 295
effective length of database: 14,309,454
effective search space: 4221288930
effective search space used: 4221288930
T: 11
A: 40
X1: 15 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 40 (21.6 bits)
S2: 63 (28.9 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.