BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens] (978 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens] 1950 0.0 gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens] 1932 0.0 gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens] 1907 0.0 gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens] 1888 0.0 gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens] 1865 0.0 gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens] 1847 0.0 gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens] 1781 0.0 gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens] 1763 0.0 gi|56549125 dynamin 2 isoform 4 [Homo sapiens] 114 4e-25 gi|56549123 dynamin 2 isoform 2 [Homo sapiens] 114 4e-25 gi|56549121 dynamin 2 isoform 1 [Homo sapiens] 114 4e-25 gi|56549119 dynamin 2 isoform 3 [Homo sapiens] 114 4e-25 gi|56549117 dynamin 1 isoform 2 [Homo sapiens] 107 5e-23 gi|59853099 dynamin 1 isoform 1 [Homo sapiens] 107 5e-23 gi|171460914 dynamin 1-like isoform 1 [Homo sapiens] 104 4e-22 gi|171460918 dynamin 1-like isoform 3 [Homo sapiens] 104 4e-22 gi|171460916 dynamin 1-like isoform 2 [Homo sapiens] 104 4e-22 gi|42544243 dynamin 3 isoform a [Homo sapiens] 103 8e-22 gi|209915561 dynamin 3 isoform b [Homo sapiens] 103 8e-22 gi|222136619 myxovirus resistance protein 1 [Homo sapiens] 102 2e-21 gi|222136617 myxovirus resistance protein 1 [Homo sapiens] 102 2e-21 gi|11342664 myxovirus resistance protein 2 [Homo sapiens] 99 3e-20 gi|110611228 utrophin [Homo sapiens] 41 0.006 gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] 39 0.018 gi|187761324 shootin1 isoform a [Homo sapiens] 39 0.018 gi|50511340 shootin1 isoform b [Homo sapiens] 39 0.018 gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo... 39 0.024 gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo... 39 0.024 gi|28173564 keratin 73 [Homo sapiens] 39 0.031 gi|148612803 keratin 6 irs4 [Homo sapiens] 38 0.053 >gi|224831248 optic atrophy 1 isoform 5 [Homo sapiens] Length = 978 Score = 1950 bits (5052), Expect = 0.0 Identities = 978/978 (100%), Positives = 978/978 (100%) Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60 Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120 Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180 Query: 181 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKVSDKEKIDQLQEEL 240 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKVSDKEKIDQLQEEL Sbjct: 181 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKVSDKEKIDQLQEEL 240 Query: 241 LHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASY 300 LHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASY Sbjct: 241 LHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASY 300 Query: 301 NTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFK 360 NTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFK Sbjct: 301 NTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFK 360 Query: 361 DSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGV 420 DSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGV Sbjct: 361 DSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGV 420 Query: 421 INTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRT 480 INTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRT Sbjct: 421 INTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRT 480 Query: 481 IFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEF 540 IFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEF Sbjct: 481 IFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEF 540 Query: 541 FQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNY 600 FQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNY Sbjct: 541 FQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNY 600 Query: 601 PRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQ 660 PRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQ Sbjct: 601 PRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQ 660 Query: 661 TMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKE 720 TMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKE Sbjct: 661 TMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKE 720 Query: 721 AVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENA 780 AVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENA Sbjct: 721 AVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENA 780 Query: 781 IENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLE 840 IENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLE Sbjct: 781 IENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLE 840 Query: 841 SRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWR 900 SRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWR Sbjct: 841 SRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWR 900 Query: 901 IQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKV 960 IQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKV Sbjct: 901 IQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKV 960 Query: 961 REIQEKLDAFIEALHQEK 978 REIQEKLDAFIEALHQEK Sbjct: 961 REIQEKLDAFIEALHQEK 978 >gi|224831253 optic atrophy 1 isoform 8 [Homo sapiens] Length = 1015 Score = 1932 bits (5004), Expect = 0.0 Identities = 978/1015 (96%), Positives = 978/1015 (96%), Gaps = 37/1015 (3%) Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60 Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120 Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180 Query: 181 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHF---------------- 224 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHF Sbjct: 181 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQ 240 Query: 225 ---------------------RKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 263 RKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK Sbjct: 241 EHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 300 Query: 264 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 323 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL Sbjct: 301 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 360 Query: 324 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 383 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL Sbjct: 361 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 420 Query: 384 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 443 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY Sbjct: 421 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 480 Query: 444 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 503 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI Sbjct: 481 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 540 Query: 504 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 563 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS Sbjct: 541 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 600 Query: 564 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 623 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV Sbjct: 601 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 660 Query: 624 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 683 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL Sbjct: 661 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 720 Query: 684 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 743 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI Sbjct: 721 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 780 Query: 744 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 803 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ Sbjct: 781 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 840 Query: 804 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 863 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF Sbjct: 841 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 900 Query: 864 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 923 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR Sbjct: 901 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 960 Query: 924 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 978 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK Sbjct: 961 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 1015 >gi|224831243 optic atrophy 1 isoform 1 [Homo sapiens] Length = 960 Score = 1907 bits (4939), Expect = 0.0 Identities = 960/978 (98%), Positives = 960/978 (98%), Gaps = 18/978 (1%) Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60 Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120 Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180 Query: 181 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKVSDKEKIDQLQEEL 240 DFFTSG SPEETAFRATDRGSESDKHFRKVSDKEKIDQLQEEL Sbjct: 181 DFFTSG------------------SPEETAFRATDRGSESDKHFRKVSDKEKIDQLQEEL 222 Query: 241 LHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASY 300 LHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASY Sbjct: 223 LHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASY 282 Query: 301 NTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFK 360 NTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFK Sbjct: 283 NTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFK 342 Query: 361 DSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGV 420 DSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGV Sbjct: 343 DSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGV 402 Query: 421 INTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRT 480 INTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRT Sbjct: 403 INTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRT 462 Query: 481 IFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEF 540 IFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEF Sbjct: 463 IFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEF 522 Query: 541 FQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNY 600 FQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNY Sbjct: 523 FQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNY 582 Query: 601 PRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQ 660 PRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQ Sbjct: 583 PRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQ 642 Query: 661 TMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKE 720 TMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKE Sbjct: 643 TMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKE 702 Query: 721 AVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENA 780 AVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENA Sbjct: 703 AVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENA 762 Query: 781 IENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLE 840 IENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLE Sbjct: 763 IENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLE 822 Query: 841 SRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWR 900 SRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWR Sbjct: 823 SRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWR 882 Query: 901 IQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKV 960 IQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKV Sbjct: 883 IQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKV 942 Query: 961 REIQEKLDAFIEALHQEK 978 REIQEKLDAFIEALHQEK Sbjct: 943 REIQEKLDAFIEALHQEK 960 >gi|224831251 optic atrophy 1 isoform 7 [Homo sapiens] Length = 997 Score = 1888 bits (4891), Expect = 0.0 Identities = 960/1015 (94%), Positives = 960/1015 (94%), Gaps = 55/1015 (5%) Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60 Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120 Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180 Query: 181 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRK-------------- 226 DFFTSG SPEETAFRATDRGSESDKHFRK Sbjct: 181 DFFTSG------------------SPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQ 222 Query: 227 -----------------------VSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 263 VSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK Sbjct: 223 EHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 282 Query: 264 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 323 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL Sbjct: 283 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 342 Query: 324 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 383 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL Sbjct: 343 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 402 Query: 384 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 443 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY Sbjct: 403 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 462 Query: 444 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 503 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI Sbjct: 463 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 522 Query: 504 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 563 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS Sbjct: 523 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 582 Query: 564 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 623 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV Sbjct: 583 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 642 Query: 624 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 683 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL Sbjct: 643 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 702 Query: 684 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 743 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI Sbjct: 703 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 762 Query: 744 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 803 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ Sbjct: 763 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 822 Query: 804 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 863 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF Sbjct: 823 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 882 Query: 864 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 923 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR Sbjct: 883 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 942 Query: 924 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 978 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK Sbjct: 943 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 997 >gi|18860833 optic atrophy 1 isoform 3 [Homo sapiens] Length = 942 Score = 1865 bits (4831), Expect = 0.0 Identities = 942/978 (96%), Positives = 942/978 (96%), Gaps = 36/978 (3%) Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60 Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120 Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180 QWKDMIPDLSEYKWIVPDIVWEIDEYIDF Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDF------------------------------- 149 Query: 181 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKVSDKEKIDQLQEEL 240 GHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKVSDKEKIDQLQEEL Sbjct: 150 -----GHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKVSDKEKIDQLQEEL 204 Query: 241 LHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASY 300 LHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASY Sbjct: 205 LHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASY 264 Query: 301 NTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFK 360 NTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFK Sbjct: 265 NTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFK 324 Query: 361 DSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGV 420 DSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGV Sbjct: 325 DSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGV 384 Query: 421 INTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRT 480 INTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRT Sbjct: 385 INTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRT 444 Query: 481 IFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEF 540 IFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEF Sbjct: 445 IFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEF 504 Query: 541 FQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNY 600 FQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNY Sbjct: 505 FQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNY 564 Query: 601 PRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQ 660 PRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQ Sbjct: 565 PRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQ 624 Query: 661 TMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKE 720 TMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKE Sbjct: 625 TMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKE 684 Query: 721 AVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENA 780 AVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENA Sbjct: 685 AVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENA 744 Query: 781 IENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLE 840 IENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLE Sbjct: 745 IENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLE 804 Query: 841 SRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWR 900 SRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWR Sbjct: 805 SRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWR 864 Query: 901 IQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKV 960 IQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKV Sbjct: 865 IQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKV 924 Query: 961 REIQEKLDAFIEALHQEK 978 REIQEKLDAFIEALHQEK Sbjct: 925 REIQEKLDAFIEALHQEK 942 >gi|18860841 optic atrophy 1 isoform 6 [Homo sapiens] Length = 979 Score = 1847 bits (4783), Expect = 0.0 Identities = 942/1015 (92%), Positives = 942/1015 (92%), Gaps = 73/1015 (7%) Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60 Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120 Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180 QWKDMIPDLSEYKWIVPDIVWEIDEYIDF Sbjct: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDF------------------------------- 149 Query: 181 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRK-------------- 226 GHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRK Sbjct: 150 -----GHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQ 204 Query: 227 -----------------------VSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 263 VSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK Sbjct: 205 EHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 264 Query: 264 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 323 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL Sbjct: 265 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 324 Query: 324 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 383 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL Sbjct: 325 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 384 Query: 384 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 443 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY Sbjct: 385 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 444 Query: 444 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 503 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI Sbjct: 445 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 504 Query: 504 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 563 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS Sbjct: 505 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 564 Query: 564 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 623 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV Sbjct: 565 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 624 Query: 624 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 683 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL Sbjct: 625 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 684 Query: 684 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 743 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI Sbjct: 685 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 744 Query: 744 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 803 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ Sbjct: 745 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 804 Query: 804 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 863 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF Sbjct: 805 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 864 Query: 864 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 923 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR Sbjct: 865 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 924 Query: 924 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 978 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK Sbjct: 925 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 979 >gi|18860831 optic atrophy 1 isoform 2 [Homo sapiens] Length = 924 Score = 1781 bits (4613), Expect = 0.0 Identities = 906/978 (92%), Positives = 913/978 (93%), Gaps = 54/978 (5%) Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60 Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120 Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180 QWKDMIP ++ EY Sbjct: 121 QWKDMIP--------------DLSEY---------------------------------- 132 Query: 181 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRKVSDKEKIDQLQEEL 240 +V +++ D + GSPEETAFRATDRGSESDKHFRKVSDKEKIDQLQEEL Sbjct: 133 ------KWIVPDIVWEIDEYIDFGSPEETAFRATDRGSESDKHFRKVSDKEKIDQLQEEL 186 Query: 241 LHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASY 300 LHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASY Sbjct: 187 LHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASY 246 Query: 301 NTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFK 360 NTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFK Sbjct: 247 NTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFK 306 Query: 361 DSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGV 420 DSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGV Sbjct: 307 DSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGV 366 Query: 421 INTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRT 480 INTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRT Sbjct: 367 INTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRT 426 Query: 481 IFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEF 540 IFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEF Sbjct: 427 IFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEF 486 Query: 541 FQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNY 600 FQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNY Sbjct: 487 FQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNY 546 Query: 601 PRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQ 660 PRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQ Sbjct: 547 PRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQ 606 Query: 661 TMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKE 720 TMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKE Sbjct: 607 TMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKE 666 Query: 721 AVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENA 780 AVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENA Sbjct: 667 AVKEESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENA 726 Query: 781 IENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLE 840 IENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLE Sbjct: 727 IENMVGPDWKKRWLYWKNRTQEQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLE 786 Query: 841 SRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWR 900 SRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWR Sbjct: 787 SRGVEVDPSLIKDTWHQVYRRHFLKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWR 846 Query: 901 IQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKV 960 IQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKV Sbjct: 847 IQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKV 906 Query: 961 REIQEKLDAFIEALHQEK 978 REIQEKLDAFIEALHQEK Sbjct: 907 REIQEKLDAFIEALHQEK 924 >gi|18860835 optic atrophy 1 isoform 4 [Homo sapiens] Length = 961 Score = 1763 bits (4565), Expect = 0.0 Identities = 906/1015 (89%), Positives = 913/1015 (89%), Gaps = 91/1015 (8%) Query: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ Sbjct: 1 MWRLRRAAVACEVCQSLVKHSSGIKGSLPLQKLHLVSRSIYHSHHPTLKLQRPQLRTSFQ 60 Query: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD Sbjct: 61 QFSSLTNLPLRKLKFSPIKYGYQPRRNFWPARLATRLLKLRYLILGSAVGGGYTAKKTFD 120 Query: 121 QWKDMIPDLSEYKWIVPDIVWEIDEYIDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLK 180 QWKDMIP ++ EY Sbjct: 121 QWKDMIP--------------DLSEY---------------------------------- 132 Query: 181 DFFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDRGSESDKHFRK-------------- 226 +V +++ D + GSPEETAFRATDRGSESDKHFRK Sbjct: 133 ------KWIVPDIVWEIDEYIDFGSPEETAFRATDRGSESDKHFRKGLLGELILLQQQIQ 186 Query: 227 -----------------------VSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 263 VSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK Sbjct: 187 EHEEEARRAAGQYSTSYAQQKRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK 246 Query: 264 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 323 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL Sbjct: 247 LVLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVL 306 Query: 324 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 383 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL Sbjct: 307 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIEL 366 Query: 384 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 443 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY Sbjct: 367 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 426 Query: 444 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 503 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI Sbjct: 427 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 486 Query: 504 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 563 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS Sbjct: 487 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 546 Query: 564 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 623 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV Sbjct: 547 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEV 606 Query: 624 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 683 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL Sbjct: 607 ISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQL 666 Query: 684 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 743 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI Sbjct: 667 PNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLRVI 726 Query: 744 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 803 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ Sbjct: 727 QHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQEQ 786 Query: 804 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 863 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF Sbjct: 787 CVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQVYRRHF 846 Query: 864 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 923 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR Sbjct: 847 LKTALNHCNLCRRGFYYYQRHFVDSELECNDVVLFWRIQRMLAITANTLRQQLTNTEVRR 906 Query: 924 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 978 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK Sbjct: 907 LEKNVKEVLEDFAEDGEKKIKLLTGKRVQLAEDLKKVREIQEKLDAFIEALHQEK 961 >gi|56549125 dynamin 2 isoform 4 [Homo sapiens] Length = 866 Score = 114 bits (285), Expect = 4e-25 Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%) Query: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339 + LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG + Sbjct: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64 Query: 340 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 399 R + + H S++F D +R EIE + +SP Sbjct: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119 Query: 400 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 459 I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++ Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179 Query: 460 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 519 D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234 Query: 520 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 576 V E I A E +FF + + A ++ T +L ++ +RE Sbjct: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291 Query: 577 SVEQQADSFKATRFNLE---TEWKNNYP 601 S+ ++ +LE E+KN P Sbjct: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319 >gi|56549123 dynamin 2 isoform 2 [Homo sapiens] Length = 870 Score = 114 bits (285), Expect = 4e-25 Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%) Query: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339 + LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG + Sbjct: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64 Query: 340 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 399 R + + H S++F D +R EIE + +SP Sbjct: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119 Query: 400 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 459 I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++ Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179 Query: 460 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 519 D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234 Query: 520 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 576 V E I A E +FF + + A ++ T +L ++ +RE Sbjct: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291 Query: 577 SVEQQADSFKATRFNLE---TEWKNNYP 601 S+ ++ +LE E+KN P Sbjct: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319 >gi|56549121 dynamin 2 isoform 1 [Homo sapiens] Length = 870 Score = 114 bits (285), Expect = 4e-25 Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%) Query: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339 + LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG + Sbjct: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64 Query: 340 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 399 R + + H S++F D +R EIE + +SP Sbjct: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119 Query: 400 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 459 I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++ Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179 Query: 460 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 519 D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234 Query: 520 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 576 V E I A E +FF + + A ++ T +L ++ +RE Sbjct: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291 Query: 577 SVEQQADSFKATRFNLE---TEWKNNYP 601 S+ ++ +LE E+KN P Sbjct: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319 >gi|56549119 dynamin 2 isoform 3 [Homo sapiens] Length = 866 Score = 114 bits (285), Expect = 4e-25 Identities = 89/328 (27%), Positives = 147/328 (44%), Gaps = 21/328 (6%) Query: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339 + LI + +++ D S S + LP++ VVG QSAGK+SVLE PRGSG + Sbjct: 7 EELIPLVNKLQDAFSSIGQSCHLD--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSGIV 64 Query: 340 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 399 R + + H S++F D +R EIE + +SP Sbjct: 65 TRRPLILQLIFSKTEHAEFLHCKSKKFT-----DFDEVRQEIEAETDRVTGTNKGISPVP 119 Query: 400 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 459 I+L V P + + L+DLPG+ PD + I + ++ +++IL + ++ Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIKDMILQFISRESSLILAVTPANM 179 Query: 460 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 519 D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234 Query: 520 VTGKGNSSE---SIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 576 V E I A E +FF + + A ++ T +L ++ +RE Sbjct: 235 VNRSQKDIEGKKDIRAALAAERKFFLSHPAYRH---MADRMGTPHLQKTLNQQLTNHIRE 291 Query: 577 SVEQQADSFKATRFNLE---TEWKNNYP 601 S+ ++ +LE E+KN P Sbjct: 292 SLPALRSKLQSQLLSLEKEVEEYKNFRP 319 >gi|56549117 dynamin 1 isoform 2 [Homo sapiens] Length = 851 Score = 107 bits (267), Expect = 5e-23 Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 15/265 (5%) Query: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339 + LI + + + D S N LP++ VVG QSAGK+SVLE PRGSG + Sbjct: 7 EDLIPLVNRLQDAFSAI--GQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63 Query: 340 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 399 +TR P+ + L A F + K D +R EIE + +SP Sbjct: 64 VTRRPLVLQLVNATTEYAEFLHCKGK----KFTDFEEVRLEIEAETDRVTGTNKGISPVP 119 Query: 400 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 459 I+L V P + + LVDLPG+ PD + I + ++ N +IL + + Sbjct: 120 INLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS 179 Query: 460 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 519 D S + ++DP G+RTI V+TK+DL ++ + + ++E KL P++ GY V Sbjct: 180 DLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234 Query: 520 VTGKG---NSSESIEAIREYEEEFF 541 V + + I A E +FF Sbjct: 235 VNRSQKDIDGKKDITAALAAERKFF 259 >gi|59853099 dynamin 1 isoform 1 [Homo sapiens] Length = 864 Score = 107 bits (267), Expect = 5e-23 Identities = 80/265 (30%), Positives = 123/265 (46%), Gaps = 15/265 (5%) Query: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339 + LI + + + D S N LP++ VVG QSAGK+SVLE PRGSG + Sbjct: 7 EDLIPLVNRLQDAFSAI--GQNADLDLPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63 Query: 340 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 399 +TR P+ + L A F + K D +R EIE + +SP Sbjct: 64 VTRRPLVLQLVNATTEYAEFLHCKGK----KFTDFEEVRLEIEAETDRVTGTNKGISPVP 119 Query: 400 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 459 I+L V P + + LVDLPG+ PD + I + ++ N +IL + + Sbjct: 120 INLRVYSPHVLNLTLVDLPGMTKVPVGDQPPDIEFQIRDMLMQFVTKENCLILAVSPANS 179 Query: 460 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 519 D S + ++DP G+RTI V+TK+DL ++ + + ++E KL P++ GY V Sbjct: 180 DLANSDALKVAKEVDPQGQRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYIGV 234 Query: 520 VTGKG---NSSESIEAIREYEEEFF 541 V + + I A E +FF Sbjct: 235 VNRSQKDIDGKKDITAALAAERKFF 259 >gi|171460914 dynamin 1-like isoform 1 [Homo sapiens] Length = 736 Score = 104 bits (260), Expect = 4e-22 Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%) Query: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339 ++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G + Sbjct: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57 Query: 340 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 383 +TR P+ + L HV+ K + E + EE D +R EIE Sbjct: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113 Query: 384 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 443 + VSPE I L + P + + LVDLPG+ D + I + + Sbjct: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173 Query: 444 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 503 + NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + + Sbjct: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229 Query: 504 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 542 + G++ P+K LG VV N ++IR+ E F Q Sbjct: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270 >gi|171460918 dynamin 1-like isoform 3 [Homo sapiens] Length = 699 Score = 104 bits (260), Expect = 4e-22 Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%) Query: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339 ++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G + Sbjct: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57 Query: 340 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 383 +TR P+ + L HV+ K + E + EE D +R EIE Sbjct: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113 Query: 384 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 443 + VSPE I L + P + + LVDLPG+ D + I + + Sbjct: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173 Query: 444 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 503 + NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + + Sbjct: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229 Query: 504 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 542 + G++ P+K LG VV N ++IR+ E F Q Sbjct: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270 >gi|171460916 dynamin 1-like isoform 2 [Homo sapiens] Length = 710 Score = 104 bits (260), Expect = 4e-22 Identities = 85/283 (30%), Positives = 135/283 (47%), Gaps = 34/283 (12%) Query: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339 ++LI + +++ DV + A LP++VVVG QS+GK+SVLE + + PRG+G + Sbjct: 2 EALIPVINKLQDVFNTVGADII---QLPQIVVVGTQSSGKSSVLESLVGRDLLPRGTG-I 57 Query: 340 MTRSPVKVTLSEGPHHVALF---KDSSREFDLTKEE-------------DLAALRHEIEL 383 +TR P+ + L HV+ K + E + EE D +R EIE Sbjct: 58 VTRRPLILQLV----HVSQEDKRKTTGEENGVEAEEWGKFLHTKNKLYTDFDEIRQEIEN 113 Query: 384 RMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAY 443 + VSPE I L + P + + LVDLPG+ D + I + + Sbjct: 114 ETERISGNNKGVSPEPIHLKIFSPNVVNLTLVDLPGMTKVPVGDQPKDIELQIRELILRF 173 Query: 444 MQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQI 503 + NPN+IIL + + D S + ++DP GRRT+ V+TK+DL + + + Sbjct: 174 ISNPNSIILAVTAANTDMATSEALKISREVDPDGRRTLAVITKLDLMDAGTDA----MDV 229 Query: 504 IEGKLFPMKALGYFAVVTGK----GNSSESIEAIREYEEEFFQ 542 + G++ P+K LG VV N ++IR+ E F Q Sbjct: 230 LMGRVIPVK-LGIIGVVNRSQLDINNKKSVTDSIRD-EYAFLQ 270 >gi|42544243 dynamin 3 isoform a [Homo sapiens] Length = 863 Score = 103 bits (257), Expect = 8e-22 Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%) Query: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339 + LI + + + D S S + LP++ VVG QSAGK+SVLE PRGSG + Sbjct: 7 EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63 Query: 340 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 399 +TR P+ + L A F + K D +R EIE + +S Sbjct: 64 VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119 Query: 400 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 459 I+L V P + + L+DLPG+ PD + I + ++ N +IL + + Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179 Query: 460 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 519 D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234 Query: 520 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 576 V + + I+A E +FF + + A ++ T +L ++ +R+ Sbjct: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291 Query: 577 SVEQQADSFKATRFNLETE---WKNNYP 601 ++ + + ++E E +KN P Sbjct: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319 >gi|209915561 dynamin 3 isoform b [Homo sapiens] Length = 859 Score = 103 bits (257), Expect = 8e-22 Identities = 88/328 (26%), Positives = 148/328 (45%), Gaps = 21/328 (6%) Query: 280 KSLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEM 339 + LI + + + D S S + LP++ VVG QSAGK+SVLE PRGSG + Sbjct: 7 EELIPLVNRLQDAFSALGQSCLLE--LPQIAVVGGQSAGKSSVLENFVGRDFLPRGSG-I 63 Query: 340 MTRSPVKVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPET 399 +TR P+ + L A F + K D +R EIE + +S Sbjct: 64 VTRRPLVLQLVTSKAEYAEFLHCKGK----KFTDFDEVRLEIEAETDRVTGMNKGISSIP 119 Query: 400 ISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSV 459 I+L V P + + L+DLPG+ PD + I + ++ N +IL + + Sbjct: 120 INLRVYSPHVLNLTLIDLPGITKVPVGDQPPDIEYQIREMIMQFITRENCLILAVTPANT 179 Query: 460 DAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 519 D S L ++DP G RTI V+TK+DL ++ + + ++E KL P++ GY V Sbjct: 180 DLANSDALKLAKEVDPQGLRTIGVITKLDLMDEGTDA----RDVLENKLLPLRR-GYVGV 234 Query: 520 VTGKG---NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRE 576 V + + I+A E +FF + + A ++ T +L ++ +R+ Sbjct: 235 VNRSQKDIDGKKDIKAAMLAERKFFLSHPAYRHI---ADRMGTPHLQKVLNQQLTNHIRD 291 Query: 577 SVEQQADSFKATRFNLETE---WKNNYP 601 ++ + + ++E E +KN P Sbjct: 292 TLPNFRNKLQGQLLSIEHEVEAYKNFKP 319 >gi|222136619 myxovirus resistance protein 1 [Homo sapiens] Length = 662 Score = 102 bits (253), Expect = 2e-21 Identities = 113/478 (23%), Positives = 210/478 (43%), Gaps = 29/478 (6%) Query: 265 VLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQD-HLPRVVVVGDQSAGKTSVL 323 V QK+ + L + +D++ A QD LP + V+GDQS+GK+SVL Sbjct: 28 VAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVL 87 Query: 324 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF-KDSSREFDLTKEEDLAALRHEIE 382 E ++ + PRGSG ++TR P+ + L + + K S +++++ + D + + EI Sbjct: 88 EALSGVAL-PRGSG-IVTRCPLVLKLKKLVNEDKWRGKVSYQDYEI-EISDASEVEKEIN 144 Query: 383 LRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKA 442 EG +S E I+L + + + L+DLPG+ D I ++ K Sbjct: 145 KAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKK 204 Query: 443 YMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQ 502 Y+Q I L + +VD + + ++DP G RTI +LTK DL +K + ++ Sbjct: 205 YIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDK--GTEDKVVD 262 Query: 503 IIEGKLFPMKALGYFAVVTGKG----NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVT 558 ++ +F +K GY +V +G S+ + E+ FF+N + +L+ + T Sbjct: 263 VVRNLVFHLKK-GYM-IVKCRGQQEIQDQLSLSEALQREKIFFENHPYFR-DLLEEGKAT 319 Query: 559 TRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNE----LFEK 614 L+ ++ + +S+ + K T + E + + E D NE L +K Sbjct: 320 VPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKYGVDIPE-DENEKMFFLIDK 378 Query: 615 AKNEILDEVISLSQVTPKHWEEILQQSLWERVSTH----VIENIYLPAAQTMNSGTFNTT 670 N ++ +L Q EE ++ R H +IEN + + + + Sbjct: 379 V-NAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIENNFQEGHKIL-----SRK 432 Query: 671 VDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIK 728 + Q+ ++LP +ET+ ++ + + EP + D ++ A + SIK Sbjct: 433 IQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMVRLAFTDVSIK 490 >gi|222136617 myxovirus resistance protein 1 [Homo sapiens] Length = 662 Score = 102 bits (253), Expect = 2e-21 Identities = 113/478 (23%), Positives = 210/478 (43%), Gaps = 29/478 (6%) Query: 265 VLQKDDKGIHHRKLKKSLIDMYSEVLDVLSDYDASYNTQD-HLPRVVVVGDQSAGKTSVL 323 V QK+ + L + +D++ A QD LP + V+GDQS+GK+SVL Sbjct: 28 VAQKNPGSVAENNLCSQYEEKVRPCIDLIDSLRALGVEQDLALPAIAVIGDQSSGKSSVL 87 Query: 324 EMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALF-KDSSREFDLTKEEDLAALRHEIE 382 E ++ + PRGSG ++TR P+ + L + + K S +++++ + D + + EI Sbjct: 88 EALSGVAL-PRGSG-IVTRCPLVLKLKKLVNEDKWRGKVSYQDYEI-EISDASEVEKEIN 144 Query: 383 LRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKA 442 EG +S E I+L + + + L+DLPG+ D I ++ K Sbjct: 145 KAQNAIAGEGMGISHELITLEISSRDVPDLTLIDLPGITRVAVGNQPADIGYKIKTLIKK 204 Query: 443 YMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQ 502 Y+Q I L + +VD + + ++DP G RTI +LTK DL +K + ++ Sbjct: 205 YIQRQETISLVVVPSNVDIATTEALSMAQEVDPEGDRTIGILTKPDLVDK--GTEDKVVD 262 Query: 503 IIEGKLFPMKALGYFAVVTGKG----NSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVT 558 ++ +F +K GY +V +G S+ + E+ FF+N + +L+ + T Sbjct: 263 VVRNLVFHLKK-GYM-IVKCRGQQEIQDQLSLSEALQREKIFFENHPYFR-DLLEEGKAT 319 Query: 559 TRNLSLAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRNE----LFEK 614 L+ ++ + +S+ + K T + E + + E D NE L +K Sbjct: 320 VPCLAEKLTSELITHICKSLPLLENQIKETHQRITEELQKYGVDIPE-DENEKMFFLIDK 378 Query: 615 AKNEILDEVISLSQVTPKHWEEILQQSLWERVSTH----VIENIYLPAAQTMNSGTFNTT 670 N ++ +L Q EE ++ R H +IEN + + + + Sbjct: 379 V-NAFNQDITALMQGEETVGEEDIRLFTRLRHEFHKWSTIIENNFQEGHKIL-----SRK 432 Query: 671 VDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIK 728 + Q+ ++LP +ET+ ++ + + EP + D ++ A + SIK Sbjct: 433 IQKFENQYRGRELPGFVNYRTFETIVKQQIKALEEPAVDMLHTVTDMVRLAFTDVSIK 490 >gi|11342664 myxovirus resistance protein 2 [Homo sapiens] Length = 715 Score = 98.6 bits (244), Expect = 3e-20 Identities = 65/214 (30%), Positives = 107/214 (50%), Gaps = 6/214 (2%) Query: 306 LPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSRE 365 LP + V+GDQS+GK+SVLE ++ + PRGSG ++TR P+ + L + P + S R Sbjct: 118 LPAIAVIGDQSSGKSSVLEALSGVAL-PRGSG-IVTRCPLVLKLKKQPCEAWAGRISYRN 175 Query: 366 FDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVT 425 +L + +D + EI G +S E ISL + P + + ++DLPG+ Sbjct: 176 TEL-ELQDPGQVEKEIHKAQNVMAGNGRGISHELISLEITSPEVPDLTIIDLPGITRVAV 234 Query: 426 SGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLT 485 D I ++ K Y+Q I L + +VD + + ++DP G RTI +LT Sbjct: 235 DNQPRDIGLQIKALIKKYIQRQQTINLVVVPCNVDIATTEALSMAHEVDPEGDRTIGILT 294 Query: 486 KVDLAEKNVASPSRIQQIIEGKLFPMKALGYFAV 519 K DL ++ + + ++ +P+K GY V Sbjct: 295 KPDLMDR--GTEKSVMNVVRNLTYPLKK-GYMIV 325 >gi|110611228 utrophin [Homo sapiens] Length = 3433 Score = 40.8 bits (94), Expect = 0.006 Identities = 157/745 (21%), Positives = 297/745 (39%), Gaps = 93/745 (12%) Query: 136 VPDIVWEIDEY-IDFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGHKLVSEVI 194 V ++ ++D Y I E++ L S+ED + D VE + KD F + + E+ Sbjct: 304 VTEVDMDLDSYQIALEEVLTWLLSAEDTFQEQDDISDDVEEV---KDQFATHEAFMMELT 360 Query: 195 GASDLLLLLGSPEETAFRATDRGSESDKHFRKVSDKEKI-----DQLQEELLHTQLKYQR 249 + GS + + +G+ SD+ ++ ++ + + L+ E + Q + Sbjct: 361 AHQSSV---GSVLQAGNQLITQGTLSDEEEFEIQEQMTLLNARWEALRVESMDRQSRLHD 417 Query: 250 ILERLEKENKELRKLVLQKDDKGIHHRKL------KKSLIDMYSEVLDVLSDYDASYNTQ 303 +L L+K+ + L ++ I + KSL + E + SD +A Sbjct: 418 VLMELQKKQLQQLSAWLTLTEERIQKMETCPLDDDVKSLQKLLEEHKSLQSDLEAEQVKV 477 Query: 304 DHLPRVVVVGDQSAGK--TSVLEMIAQA-----RIFPRGSGEMMTR-SPVKVTLSEGPHH 355 + L +VV+ D+++G+ T++LE Q R + E R + + E Sbjct: 478 NSLTHMVVIVDENSGESATAILEDQLQKLGERWTAVCRWTEERWNRLQEINILWQELLEE 537 Query: 356 VALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVKGPGLQRMVLV 415 L K E KEE L ++++ K+ KE +VS +++ + ++R L Sbjct: 538 QCLLKAWLTE----KEEAL----NKVQTSNFKDQKE-LSVSVRRLAILKEDMEMKRQTLD 588 Query: 416 DLPGVINTVTSGMAPDTKET---IFSISKAYMQNPNAIILCIQDGSVDAERSIVTDLVSQ 472 L + V G D + I S S+ Q ++++ ++D S +++ +SQ Sbjct: 589 QLSEIGQDV--GQLLDNSKASKKINSDSEELTQRWDSLVQRLEDSSNQVTQAVAKLGMSQ 646 Query: 473 MDPHG-RRTIFV----LTKVDLAEKNVASPSRIQQI---IEGK----LFPMKALGYFAVV 520 + T+ V +TK E P + +QI IE K + L + Sbjct: 647 IPQKDLLETVRVREQAITKKSKQELPPPPPPKKRQIHVDIEAKKKFDAISAELLNWIL-- 704 Query: 521 TGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQ 580 K ++ I+EY + Q++ +K LKA + R + +D + + VEQ Sbjct: 705 --KWKTAIQTTEIKEYMK--MQDTSEMK-KKLKALEKEQRE-RIPRADELNQTGQILVEQ 758 Query: 581 Q------ADSFKATRFNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQV--TPK 632 + K + +EWKN L +L+R ++ N ++ L +V T + Sbjct: 759 MGKEGLPTEEIKNVLEKVSSEWKNVSQHLEDLERKIQLQEDINAYFKQLDELEKVIKTKE 818 Query: 633 HW------EEILQQSL------WERVSTHVI---ENIYLPAAQTMNSGTFNTTVDIKLKQ 677 W E +QSL +R T+++ I + A + + D + Sbjct: 819 EWVKHTSISESSRQSLPSLKDSCQRELTNLLGLHPKIEMARASCSALMSQPSAPDFVQRG 878 Query: 678 WTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAE 737 + +AV+ A E Q+ + G + + LK+ + + K A+ Sbjct: 879 FDSFLGRYQAVQEAVEDRQQHLENELKGQPGHAYLETLKTLKDVLNDSENK-------AQ 931 Query: 738 DSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWK 797 SL V+ A ++++ +K+ D + + AL +L + A+E V PD +K LY + Sbjct: 932 VSLNVLNDLAKVEKALQEKKTLDEILENQKPALH-KLAEETKALEKNVHPDVEK--LYKQ 988 Query: 798 NRTQEQCVHNETKNELEKMLKCNEE 822 Q N+ K + K L EE Sbjct: 989 EFDDVQGKWNKLKVLVSKDLHLLEE 1013 >gi|6715600 golgi autoantigen, golgin subfamily a, 4 [Homo sapiens] Length = 2230 Score = 39.3 bits (90), Expect = 0.018 Identities = 145/792 (18%), Positives = 311/792 (39%), Gaps = 129/792 (16%) Query: 229 DKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHHRKLKKSL---IDM 285 DK K+ +L +L T ++Q + EK NK L +DK + +KL + L +D+ Sbjct: 1167 DKRKVSELTSKLKTTDEEFQSLKSSHEKSNKSL-------EDKSLEFKKLSEELAIQLDI 1219 Query: 286 YSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLEMIAQARIFPRGSGEMMTRSPV 345 + + L + + + + + + + +A + + + Sbjct: 1220 CCKKTEALLEAKTNELINISSSKTNAILSRISHCQHRTTKVKEALLIKTCTVSELEAQLR 1279 Query: 346 KVTLSEGPHHVALFKDSSREFDLTKEEDLAALRHEIELRMRKNVKEGCTVSPETISLNVK 405 ++T + +++ F+ ++ + + KE + +++ +IE ++ E +L + Sbjct: 1280 QLTEEQNTLNIS-FQQATHQLE-EKENQIKSMKADIE-----------SLVTEKEALQKE 1326 Query: 406 GPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQNPNAIILCIQDGSVDAERSI 465 G Q+ A + + I + K +N NA+ L ++ + ++ Sbjct: 1327 GGNQQQA----------------ASEKESCITQLKKELSENINAVTLMKEE--LKEKKVE 1368 Query: 466 VTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSRIQQIIEGK---LFPMKALGYFAVVTG 522 ++ L Q+ + + + L+EK A S +Q E K L ++ L F V T Sbjct: 1369 ISSLSKQLTD---LNVQLQNSISLSEKEAAISSLRKQYDEEKCELLDQVQDLS-FKVDTL 1424 Query: 523 KGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVS---------DCFWKM 573 ++E + ++ +F + K + S HQ T + L + + D + Sbjct: 1425 SKEKISALEQVDDWSNKFSEWKKKAQ-SRFTQHQNTVKELQIQLELKSKEAYEKDEQINL 1483 Query: 574 VRESVEQQADSFKATR--------------FNLETEWKNNYPRLRELDRNELFEKAKNEI 619 ++E ++QQ F + NLETE K+ R+ EL+ + + + E Sbjct: 1484 LKEELDQQNKRFDCLKGEMEDDKSKMEKKESNLETELKSQTARIMELEDHITQKTIEIES 1543 Query: 620 LDEVI-SLSQVTPKHWEEILQ-----QSLWERVSTHVIE----------NIYLPAAQTMN 663 L+EV+ + +Q +E++Q Q L E V E +Y A+ Sbjct: 1544 LNEVLKNYNQQKDIEHKELVQKLQHFQELGEEKDNRVKEAEEKILTLENQVYSMKAELET 1603 Query: 664 SGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVK 723 V++ +K K+ KA+E + L+ E + + E K K I K+ + Sbjct: 1604 KKKELEHVNLSVK---SKEEELKALE---DRLESESAAKLAELKRKAEQKIAAIKKQLLS 1657 Query: 724 EESIKRHKWNDFAEDSLRVIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENA-IE 782 + K ++ E L + + Q+ + ++ +EE +LK E++ E Sbjct: 1658 QMEEKEEQYKKGTESHLSELN---------TKLQEREREVHILEE----KLKSVESSQSE 1704 Query: 783 NMVGPDWKKRWLYWKNRTQ---EQCV---HNETKNELEKMLKCNEEHPAYLASDEITTVR 836 ++ P K + + + + CV + E + L++ L E+ + ++ TV Sbjct: 1705 TLIVPRSAKNVAAYTEQEEADSQGCVQKTYEEKISVLQRNLTEKEKLLQRVGQEKEETVS 1764 Query: 837 KNLESRGVEVDPSLIKDTWHQVYRRHFLKTALNH----CNLCRRGFYYYQRHFVDSELEC 892 + E R + LIK H ++H ++ + H + + V+ E Sbjct: 1765 SHFEMR-CQYQERLIK-LEHAEAKQHEDQSMIGHLQEELEEKNKKYSLIVAQHVEKEGGK 1822 Query: 893 NDVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQ 952 N++ ++ + TL+++ ++ LE+ +KE+ D +K++ RV+ Sbjct: 1823 NNIQAKQNLENVFDDVQKTLQEKELTCQI--LEQKIKEL--DSCLVRQKEV-----HRVE 1873 Query: 953 LAEDLKKVREIQ 964 + E K ++Q Sbjct: 1874 MEELTSKYEKLQ 1885 Score = 37.0 bits (84), Expect = 0.090 Identities = 125/656 (19%), Positives = 251/656 (38%), Gaps = 135/656 (20%) Query: 219 ESDKHFRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRK---LVLQKDDKGIHH 275 ES KH + EK+ L+++ Q + +++ E+ E+E + L K ++ Q + ++ Sbjct: 617 ESLKHQQDALWTEKLQVLKQQY---QTEMEKLREKCEQEKETLLKDKEIIFQAHIEEMNE 673 Query: 276 RKLKK------SLIDMYSEVLDVLSDYDASYNTQDHLPRVVVVGDQSAGKTSVLE--MIA 327 + L+K L + SE+ +VL A + ++ L V+ DQ+ LE M Sbjct: 674 KTLEKLDVKQTELESLSSELSEVLK---ARHKLEEELS---VLKDQTDKMKQELEAKMDE 727 Query: 328 QARIFPRGSGEMMTRSPVKVTLSEGPHHVALFKDSSREFDLT-KEEDLAALRHEIELR-M 385 Q + ++ V + +E KD + +L KE D H+ + + Sbjct: 728 QKNHHQQQVDSIIKEHEVSIQRTE-----KALKDQINQLELLLKERDKHLKEHQAHVENL 782 Query: 386 RKNVKEGCTVSPETISLNVKGPGLQRMVLVDLPGVINTVTSGMAPDTKETIFSISKAYMQ 445 ++K +G Q +D+ + T +E + + + + Sbjct: 783 EADIKRS------------EGELQQASAKLDVFQSYQSATHEQTKAYEEQLAQLQQKLLD 830 Query: 446 -NPNAIILCIQDGSVDAERSIVTDLVSQMDPHGRRTIFVLTKVDLAEKNVASPSR-IQQI 503 I+L Q V+A++ D+ +++D H + ++ +++ + + + Q+ Sbjct: 831 LETERILLTKQVAEVEAQKK---DVCTELDAHKIQVQDLMQQLEKQNSEMEQKVKSLTQV 887 Query: 504 IEGKLFPMKALGYFAVVTGKGNSSESIEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLS 563 E KL G ++ + + E E Q ++ K ++ T+ LS Sbjct: 888 YESKL-----------EDGNKEQEQTKQILVEKENMILQ----MREGQKKEIEILTQKLS 932 Query: 564 LAVSDCFWKMVRESVEQQADSFKATRFNLETEWKNNYPRLRELDRN--ELFEKAKNEILD 621 + DS ET++KN ++ ++ + E+ E K ++LD Sbjct: 933 A----------------KEDSIHILNEEYETKFKNQEKKMEKVKQKAKEMQETLKKKLLD 976 Query: 622 EVISLSQVTPKHWEEILQQSLWERVSTHVIENIYLPAAQTMNSGTFNTTVDIKLKQWTDK 681 + L + E+ Q+ ++ + ++E AQ ++G + + Sbjct: 977 QEAKLKKELENTALELSQKE--KQFNAKMLE-----MAQANSAGISDAVSRL-------- 1021 Query: 682 QLPNKAVEVAWETLQEEFSRFMTEPKGKEHDDIFDKLKEAVKEESIKRHKWNDFAEDSLR 741 ET Q+E +TE +E +D+ SI K N AE+ L+ Sbjct: 1022 -----------ETNQKEQIESLTEVHRRELNDVI----------SIWEKKLNQQAEE-LQ 1059 Query: 742 VIQHNALEDRSISDKQQWDAAIYFMEEALQARLKDTENAIENMVGPDWKKRWLYWKNRTQ 801 I L+++ + + F E + + T WL + Sbjct: 1060 EIHEIQLQEKEQEVAELKQKILLFGCEKEEMNKEIT---------------WL-----KE 1099 Query: 802 EQCVHNETKNELEKMLKCNEEHPAYLASDEITTVRKNLESRGVEVDPSLIKDTWHQ 857 E + T NEL++ LK H LA DE T ++ +LE V+++ SL ++T+ Q Sbjct: 1100 EGVKQDTTLNELQEQLKQKSAHVNSLAQDE-TKLKAHLEKLEVDLNKSLKENTFLQ 1154 >gi|187761324 shootin1 isoform a [Homo sapiens] Length = 631 Score = 39.3 bits (90), Expect = 0.018 Identities = 40/151 (26%), Positives = 70/151 (46%), Gaps = 27/151 (17%) Query: 148 DFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGHKLVSEVIGASDLLLLLGSPE 207 ++E+++ L +DL K A F ++ F +KL + S LLL P+ Sbjct: 213 EYEEMQVNLELEKDLRKKAESF---------AQEMFIEQNKLKRQ----SHLLLQSSIPD 259 Query: 208 ETAFRATDRGS--------ESDKHFRKVSDKEKIDQLQEELLHTQL-KYQRILERLEKEN 258 + +A D + E +H +KV + E +QL+ E LH ++ ++ LE LE++ Sbjct: 260 QQLLKALDENAKLTQQLEEERIQHQQKVKELE--EQLENETLHKEIHNLKQQLELLEEDK 317 Query: 259 KELRKLVLQKDDKGIHHRKLKKSLIDMYSEV 289 KEL ++K R LK S+ ++ V Sbjct: 318 KELELKYQNSEEKA---RNLKHSVDELQKRV 345 >gi|50511340 shootin1 isoform b [Homo sapiens] Length = 456 Score = 39.3 bits (90), Expect = 0.018 Identities = 40/151 (26%), Positives = 70/151 (46%), Gaps = 27/151 (17%) Query: 148 DFEKIRKALPSSEDLVKLAPDFDKIVESLSLLKDFFTSGHKLVSEVIGASDLLLLLGSPE 207 ++E+++ L +DL K A F ++ F +KL + S LLL P+ Sbjct: 213 EYEEMQVNLELEKDLRKKAESF---------AQEMFIEQNKLKRQ----SHLLLQSSIPD 259 Query: 208 ETAFRATDRGS--------ESDKHFRKVSDKEKIDQLQEELLHTQL-KYQRILERLEKEN 258 + +A D + E +H +KV + E +QL+ E LH ++ ++ LE LE++ Sbjct: 260 QQLLKALDENAKLTQQLEEERIQHQQKVKELE--EQLENETLHKEIHNLKQQLELLEEDK 317 Query: 259 KELRKLVLQKDDKGIHHRKLKKSLIDMYSEV 289 KEL ++K R LK S+ ++ V Sbjct: 318 KELELKYQNSEEKA---RNLKHSVDELQKRV 345 >gi|134304846 Rb1-inducible coiled coil protein 1 isoform 2 [Homo sapiens] Length = 1591 Score = 38.9 bits (89), Expect = 0.024 Identities = 46/243 (18%), Positives = 97/243 (39%), Gaps = 25/243 (10%) Query: 530 IEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATR 589 + + + F+ K LK +++ LS + E + QQ + ++A Sbjct: 1155 LNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELS-----ALERQKDEKITQQEEKYEAII 1209 Query: 590 FNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTH 649 NLE + + +E DR +L +K E DE I + K E++++ L E+V Sbjct: 1210 QNLEKD-RQKLVSSQEQDREQLIQKLNCE-KDEAIQTALKEFKLEREVVEKELLEKVKHL 1267 Query: 650 VIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEE----------- 698 + PA + + + +++ K +K + +E + EE Sbjct: 1268 ENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAE 1327 Query: 699 ----FSRFMTEPKGKEHD---DIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDR 751 F+ +T K ++ + D+ DKLK ++++ + +ED R+++ + Sbjct: 1328 QQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEE 1387 Query: 752 SIS 754 +S Sbjct: 1388 EVS 1390 Score = 35.0 bits (79), Expect = 0.34 Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 4/128 (3%) Query: 159 SEDLVKLAPDFDKIVESLSLLKD--FFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDR 216 SED +L + K+ E +S L+ F S + + + + L G + +A D Sbjct: 1372 SEDRARLLEEKKKLEEEVSKLRSSSFVPSPYVATAPELYGACAPELPGESDRSAVETADE 1431 Query: 217 GS-ESDKHFRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHH 275 G +S +S +E I L EE L +R L+ E+ENK L + ++ + + Sbjct: 1432 GRVDSAMETSMMSVQENIHMLSEEKQRIML-LERTLQLKEEENKRLNQRLMSQSMSSVSS 1490 Query: 276 RKLKKSLI 283 R +K I Sbjct: 1491 RHSEKIAI 1498 >gi|134304842 Rb1-inducible coiled coil protein 1 isoform 1 [Homo sapiens] Length = 1594 Score = 38.9 bits (89), Expect = 0.024 Identities = 46/243 (18%), Positives = 97/243 (39%), Gaps = 25/243 (10%) Query: 530 IEAIREYEEEFFQNSKLLKTSMLKAHQVTTRNLSLAVSDCFWKMVRESVEQQADSFKATR 589 + + + F+ K LK +++ LS + E + QQ + ++A Sbjct: 1155 LNKVTSLHNQAFEIEKNLKEQIIELQSKLDSELS-----ALERQKDEKITQQEEKYEAII 1209 Query: 590 FNLETEWKNNYPRLRELDRNELFEKAKNEILDEVISLSQVTPKHWEEILQQSLWERVSTH 649 NLE + + +E DR +L +K E DE I + K E++++ L E+V Sbjct: 1210 QNLEKD-RQKLVSSQEQDREQLIQKLNCE-KDEAIQTALKEFKLEREVVEKELLEKVKHL 1267 Query: 650 VIENIYLPAAQTMNSGTFNTTVDIKLKQWTDKQLPNKAVEVAWETLQEE----------- 698 + PA + + + +++ K +K + +E + EE Sbjct: 1268 ENQIAKSPAIDSTRGDSSSLVAELQEKLQEEKAKFLEQLEEQEKRKNEEMQNVRTSLIAE 1327 Query: 699 ----FSRFMTEPKGKEHD---DIFDKLKEAVKEESIKRHKWNDFAEDSLRVIQHNALEDR 751 F+ +T K ++ + D+ DKLK ++++ + +ED R+++ + Sbjct: 1328 QQTNFNTVLTREKMRKENIINDLSDKLKSTMQQQERDKDLIESLSEDRARLLEEKKKLEE 1387 Query: 752 SIS 754 +S Sbjct: 1388 EVS 1390 Score = 35.0 bits (79), Expect = 0.34 Identities = 33/128 (25%), Positives = 56/128 (43%), Gaps = 4/128 (3%) Query: 159 SEDLVKLAPDFDKIVESLSLLKD--FFTSGHKLVSEVIGASDLLLLLGSPEETAFRATDR 216 SED +L + K+ E +S L+ F S + + + + L G + +A D Sbjct: 1372 SEDRARLLEEKKKLEEEVSKLRSSSFVPSPYVATAPELYGACAPELPGESDRSAVETADE 1431 Query: 217 GS-ESDKHFRKVSDKEKIDQLQEELLHTQLKYQRILERLEKENKELRKLVLQKDDKGIHH 275 G +S +S +E I L EE L +R L+ E+ENK L + ++ + + Sbjct: 1432 GRVDSAMETSMMSVQENIHMLSEEKQRIML-LERTLQLKEEENKRLNQRLMSQSMSSVSS 1490 Query: 276 RKLKKSLI 283 R +K I Sbjct: 1491 RHSEKIAI 1498 >gi|28173564 keratin 73 [Homo sapiens] Length = 540 Score = 38.5 bits (88), Expect = 0.031 Identities = 23/72 (31%), Positives = 40/72 (55%), Gaps = 3/72 (4%) Query: 894 DVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQL 953 D V F Q + T L QQL ++ + N++ +LE + + K+++ L+G RV+L Sbjct: 148 DKVRFLEQQNQVLETKWELLQQL---DLNNCKNNLEPILEGYISNLRKQLETLSGDRVRL 204 Query: 954 AEDLKKVREIQE 965 +L+ VRE+ E Sbjct: 205 DSELRSVREVVE 216 >gi|148612803 keratin 6 irs4 [Homo sapiens] Length = 529 Score = 37.7 bits (86), Expect = 0.053 Identities = 22/72 (30%), Positives = 41/72 (56%), Gaps = 3/72 (4%) Query: 894 DVVLFWRIQRMLAITANTLRQQLTNTEVRRLEKNVKEVLEDFAEDGEKKIKLLTGKRVQL 953 D V F Q + T L QQL ++ +KN++ +LE + + K+++ L+G RV+L Sbjct: 156 DKVRFLEQQNQVLETKWELLQQL---DLNNCKKNLEPILEGYISNLRKQLETLSGDRVRL 212 Query: 954 AEDLKKVREIQE 965 +L+ +R++ E Sbjct: 213 DSELRSMRDLVE 224 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.317 0.132 0.384 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 35,010,912 Number of Sequences: 37866 Number of extensions: 1547438 Number of successful extensions: 7203 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 55 Number of HSP's successfully gapped in prelim test: 102 Number of HSP's that attempted gapping in prelim test: 6864 Number of HSP's gapped (non-prelim): 455 length of query: 978 length of database: 18,247,518 effective HSP length: 112 effective length of query: 866 effective length of database: 14,006,526 effective search space: 12129651516 effective search space used: 12129651516 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.7 bits) S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.