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Search of human proteins with 115430255
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|115430255 solute carrier family 39 (zinc transporter),
member 4 isoform 2 [Homo sapiens]
(647 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|115430255 solute carrier family 39 (zinc transporter), member... 1288 0.0
gi|115430259 solute carrier family 39 (zinc transporter), member... 1170 0.0
gi|223633939 solute carrier family 39 (zinc transporter), member... 290 3e-78
gi|223633937 solute carrier family 39 (zinc transporter), member... 275 9e-74
gi|190358541 solute carrier family 39 (zinc transporter), member... 204 2e-52
gi|206597541 solute carrier family 39 (metal ion transporter), m... 201 1e-51
gi|206597539 solute carrier family 39 (metal ion transporter), m... 201 1e-51
gi|205830424 solute carrier family 39 (zinc transporter), member... 197 2e-50
gi|190360568 solute carrier family 39 (zinc transporter), member... 197 2e-50
gi|24586665 solute carrier family 39 (zinc transporter), member ... 186 4e-47
gi|205830403 solute carrier family 39 (zinc transporter), member... 186 4e-47
gi|205830407 solute carrier family 39 (zinc transporter), member... 184 3e-46
gi|205830426 solute carrier family 39 (zinc transporter), member... 176 6e-44
gi|205830405 solute carrier family 39 (zinc transporter), member... 170 3e-42
gi|187936949 solute carrier family 39 (zinc transporter), member... 161 2e-39
gi|55741750 solute carrier family 39 (zinc transporter), member ... 161 2e-39
gi|153252201 solute carrier family 39 (zinc transporter), member... 154 2e-37
gi|117553619 solute carrier family 39, member 7 [Homo sapiens] 146 5e-35
gi|117553608 solute carrier family 39, member 7 [Homo sapiens] 146 5e-35
gi|153252214 solute carrier family 39 (zinc transporter), member... 130 3e-30
gi|40255101 solute carrier family 39 (zinc transporter), member ... 116 6e-26
gi|190014617 solute carrier family 39 (zinc transporter), member... 115 1e-25
gi|40254928 solute carrier family 39 (zinc transporter), member ... 51 3e-06
gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo... 50 6e-06
gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo... 50 6e-06
gi|156415986 solute carrier family 39 (zinc transporter), member... 45 2e-04
gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens] 33 0.82
gi|239741896 PREDICTED: hypothetical protein XP_002342335 [Homo ... 33 0.82
gi|41352721 solute carrier family 36 member 1 [Homo sapiens] 32 1.8
gi|30794216 tripartite motif-containing 56 [Homo sapiens] 31 3.1
>gi|115430255 solute carrier family 39 (zinc transporter), member 4
isoform 2 [Homo sapiens]
Length = 647
Score = 1288 bits (3332), Expect = 0.0
Identities = 647/647 (100%), Positives = 647/647 (100%)
Query: 1 MASLVSLELGLLLAVLVVTATASPPAGLLSLLTSGQGALDQEALGGLLNTLADRVHCANG 60
MASLVSLELGLLLAVLVVTATASPPAGLLSLLTSGQGALDQEALGGLLNTLADRVHCANG
Sbjct: 1 MASLVSLELGLLLAVLVVTATASPPAGLLSLLTSGQGALDQEALGGLLNTLADRVHCANG 60
Query: 61 PCGKCLSVEDALGLGEPEGSGLPPGPVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWA 120
PCGKCLSVEDALGLGEPEGSGLPPGPVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWA
Sbjct: 61 PCGKCLSVEDALGLGEPEGSGLPPGPVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWA 120
Query: 121 SHADHLLALLESPKALTPGLSWLLQRMQARAAGQTPKTACVDIPQLLEEAVGAGAPGSAG 180
SHADHLLALLESPKALTPGLSWLLQRMQARAAGQTPKTACVDIPQLLEEAVGAGAPGSAG
Sbjct: 121 SHADHLLALLESPKALTPGLSWLLQRMQARAAGQTPKTACVDIPQLLEEAVGAGAPGSAG 180
Query: 181 GVLAALLDHVRSGSCFHALPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGVGREAHSD 240
GVLAALLDHVRSGSCFHALPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGVGREAHSD
Sbjct: 181 GVLAALLDHVRSGSCFHALPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGVGREAHSD 240
Query: 241 HSHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPAL 300
HSHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPAL
Sbjct: 241 HSHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPAL 300
Query: 301 LQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYI 360
LQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYI
Sbjct: 301 LQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYI 360
Query: 361 LQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLF 420
LQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLF
Sbjct: 361 LQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLF 420
Query: 421 NLLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPE 480
NLLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPE
Sbjct: 421 NLLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPE 480
Query: 481 LLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPH 540
LLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPH
Sbjct: 481 LLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPH 540
Query: 541 ELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYV 600
ELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYV
Sbjct: 541 ELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYV 600
Query: 601 ALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDITF 647
ALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDITF
Sbjct: 601 ALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDITF 647
>gi|115430259 solute carrier family 39 (zinc transporter), member 4
isoform 1 [Homo sapiens]
Length = 622
Score = 1170 bits (3026), Expect = 0.0
Identities = 584/586 (99%), Positives = 585/586 (99%)
Query: 62 CGKCLSVEDALGLGEPEGSGLPPGPVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWAS 121
C +CLSVEDALGLGEPEGSGLPPGPVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWAS
Sbjct: 37 CPQCLSVEDALGLGEPEGSGLPPGPVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWAS 96
Query: 122 HADHLLALLESPKALTPGLSWLLQRMQARAAGQTPKTACVDIPQLLEEAVGAGAPGSAGG 181
HADHLLALLESPKALTPGLSWLLQRMQARAAGQTPKTACVDIPQLLEEAVGAGAPGSAGG
Sbjct: 97 HADHLLALLESPKALTPGLSWLLQRMQARAAGQTPKTACVDIPQLLEEAVGAGAPGSAGG 156
Query: 182 VLAALLDHVRSGSCFHALPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGVGREAHSDH 241
VLAALLDHVRSGSCFHALPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGVGREAHSDH
Sbjct: 157 VLAALLDHVRSGSCFHALPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGVGREAHSDH 216
Query: 242 SHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALL 301
SHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALL
Sbjct: 217 SHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALL 276
Query: 302 QQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYIL 361
QQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYIL
Sbjct: 277 QQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYIL 336
Query: 362 QTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFN 421
QTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFN
Sbjct: 337 QTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFN 396
Query: 422 LLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL 481
LLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL
Sbjct: 397 LLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL 456
Query: 482 LNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHE 541
LNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHE
Sbjct: 457 LNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHE 516
Query: 542 LGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVA 601
LGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVA
Sbjct: 517 LGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVA 576
Query: 602 LCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDITF 647
LCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDITF
Sbjct: 577 LCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDITF 622
>gi|223633939 solute carrier family 39 (zinc transporter), member 12
isoform 1 [Homo sapiens]
Length = 691
Score = 290 bits (742), Expect = 3e-78
Identities = 210/671 (31%), Positives = 322/671 (47%), Gaps = 66/671 (9%)
Query: 21 TASPPAGLLSLLTSGQGALDQEALGGLLNTLADRVHCAN------GPCGKCLSVEDALGL 74
++ PA LL +L++G + L+ TL ++ C G C C
Sbjct: 39 SSGQPADLLQVLSAGDHPPHNHSRS-LIKTLLEKTGCPRRRNGMQGDCNLCF-------- 89
Query: 75 GEPEGSGLPPG----PVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWASHADHLLALL 130
EP+ L G L V R+S + Y+ + E C + +L +LL
Sbjct: 90 -EPDALLLIAGGNFEDQLREEVVQRVSLLLLYYIIHQEEICSSKLNMSNKEYKFYLHSLL 148
Query: 131 ESPKALTPGLSWLLQRMQ------ARAAGQTPKTACVDIPQLLEEAVGAGAPGSAGGVL- 183
+ S+L Q R T ++ C++ L +++ + G+ L
Sbjct: 149 SLRQ--DEDSSFLSQNETEDILAFTRQYFDTSQSQCMETKTLQKKSGIVSSEGANESTLP 206
Query: 184 ---AALLDHVRSGSCFHA--LPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGV----- 233
A ++ G C LPSP YF +++F + + L+EL L+ L
Sbjct: 207 QLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSSLNRTNTLRLSELDQLLNTLWTRSTCI 266
Query: 234 -GREAHSDHSHRHRGASSRDPVPLISSSNSSSV------WDTVCLSARDVMAAYGLSEQA 286
+ H ++ + SSS WD C SAR ++ + +
Sbjct: 267 KNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLS 326
Query: 287 GVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLL 346
++ E + Q+SP ++QQ LS +C + + E+Y Y ++A L+ L ++ G
Sbjct: 327 LISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTA 386
Query: 347 LLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGL-----SPQPTW 401
L+ C ILQ F+ LAVG L+GDA+LHL P+VLGLH S W
Sbjct: 387 LVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIW 446
Query: 402 RLLAMLAGLYAFFLFENLFNLLL-PRDPEDLE--DGPCGHSSH----SHGGHSHGVSLQL 454
+L+ ++ G++ FFL E F LL+ P D + L +G GHS H S G
Sbjct: 447 KLMGLIGGIHGFFLIEKCFILLVSPNDKQGLSLVNGHVGHSHHLALNSELSDQAGRGKSA 506
Query: 455 APSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLA 514
+ +L+ P+ D A E P R + LL MI +GD++HNFADGLA
Sbjct: 507 STIQLKSPE--------DSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLA 558
Query: 515 VGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLY 574
+GAAF+SS ++G+ T++A+ CHE+PHE+GDFA LL +GLS++ A+L+N S+LTAF GLY
Sbjct: 559 IGAAFSSSSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLY 618
Query: 575 VALAVGVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTV 634
+ L+V + WI V G+FLY++L +MLP M V+ RPW++FLL N GL+ GW
Sbjct: 619 IGLSVSADPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLS 678
Query: 635 LLLLSLYEDDI 645
LLLL++YE +I
Sbjct: 679 LLLLAIYEQNI 689
>gi|223633937 solute carrier family 39 (zinc transporter), member 12
isoform 2 [Homo sapiens]
Length = 654
Score = 275 bits (703), Expect = 9e-74
Identities = 200/664 (30%), Positives = 311/664 (46%), Gaps = 89/664 (13%)
Query: 21 TASPPAGLLSLLTSGQGALDQEALGGLLNTLADRVHCAN------GPCGKCLSVEDALGL 74
++ PA LL +L++G + L+ TL ++ C G C C
Sbjct: 39 SSGQPADLLQVLSAGDHPPHNHSRS-LIKTLLEKTGCPRRRNGMQGDCNLCF-------- 89
Query: 75 GEPEGSGLPPG----PVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWASHADHLLALL 130
EP+ L G L V R+S + Y+ + E C + +L +LL
Sbjct: 90 -EPDALLLIAGGNFEDQLREEVVQRVSLLLLYYIIHQEEICSSKLNMSNKEYKFYLHSLL 148
Query: 131 ESPKALTPGLSWLLQRMQ------ARAAGQTPKTACVDIPQLLEEAVGAGAPGSAGGVL- 183
+ S+L Q R T ++ C++ L +++ + G+ L
Sbjct: 149 SLRQ--DEDSSFLSQNETEDILAFTRQYFDTSQSQCMETKTLQKKSGIVSSEGANESTLP 206
Query: 184 ---AALLDHVRSGSCFHA--LPSPQYFVDFVFQQHSSEVPMTLAELSALMQRLGV----- 233
A ++ G C LPSP YF +++F + + L+EL L+ L
Sbjct: 207 QLAAMIITLSLQGVCLGQGNLPSPDYFTEYIFSSLNRTNTLRLSELDQLLNTLWTRSTCI 266
Query: 234 -GREAHSDHSHRHRGASSRDPVPLISSSNSSSV------WDTVCLSARDVMAAYGLSEQA 286
+ H ++ + SSS WD C SAR ++ + +
Sbjct: 267 KNEKIHQFQRKQNNIITHDQDYSNFSSSMEKESEDGPVSWDQTCFSARQLVEIFLQKGLS 326
Query: 287 GVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLL 346
++ E + Q+SP ++QQ LS +C + + E+Y Y ++A L+ L ++ G
Sbjct: 327 LISKEDFKQMSPGIIQQLLSCSCHLPKDQQAKLPPTTLEKYGYSTVAVTLLTLGSMLGTA 386
Query: 347 LLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGL-----SPQPTW 401
L+ C ILQ F+ LAVG L+GDA+LHL P+VLGLH S W
Sbjct: 387 LVLFHSCEENYRLILQLFVGLAVGTLSGDALLHLIPQVLGLHKQEAPEFGHFHESKGHIW 446
Query: 402 RLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSELRQ 461
+L+ ++ G++ FFL E F LL+ +P++ +
Sbjct: 447 KLMGLIGGIHGFFLIEKCFILLV------------------------------SPNDKKS 476
Query: 462 PKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFAS 521
P+ D A E P R + LL MI +GD++HNFADGLA+GAAF+S
Sbjct: 477 PE--------DSQAAEMPIGSMTASNRKCKAISLLAIMILVGDSLHNFADGLAIGAAFSS 528
Query: 522 SWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGV 581
S ++G+ T++A+ CHE+PHE+GDFA LL +GLS++ A+L+N S+LTAF GLY+ L+V
Sbjct: 529 SSESGVTTTIAILCHEIPHEMGDFAVLLSSGLSMKTAILMNFISSLTAFMGLYIGLSVSA 588
Query: 582 SEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLLLSLY 641
+ WI V G+FLY++L +MLP M V+ RPW++FLL N GL+ GW LLLL++Y
Sbjct: 589 DPCVQDWIFTVTAGMFLYLSLVEMLPEMTHVQTQRPWMMFLLQNFGLILGWLSLLLLAIY 648
Query: 642 EDDI 645
E +I
Sbjct: 649 EQNI 652
>gi|190358541 solute carrier family 39 (zinc transporter), member 14
isoform b [Homo sapiens]
Length = 492
Score = 204 bits (520), Expect = 2e-52
Identities = 148/480 (30%), Positives = 233/480 (48%), Gaps = 72/480 (15%)
Query: 205 FVDFVFQQHSSEVPMTLAELSALMQRL--GVGREAHSDHSHRHRGASSRDPVPLISSSNS 262
F+ + ++ +TL +L AL+ L GVGR + H HR S+
Sbjct: 43 FLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNLST------------ 90
Query: 263 SSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLS 322
C S+ D+ A+ SEQ+ + + P +LQQ S ACTS+++ +++ +
Sbjct: 91 -------CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQT 143
Query: 323 QSER------YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDA 376
+ R + +G L+ LI L ++ G+L+L CT + +L F++L++G L +A
Sbjct: 144 EEGRPSAVEVWGFGFLSVSLINLASLLGVLVLPCTE-KAFFSRVLTYFIALSIGTLLSNA 202
Query: 377 VLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPC 436
+ L P+ G + + +S + + G Y FF E + +LL + E
Sbjct: 203 LFQLIPEAFGFNPLEDYYVS-----KSAVVFGGFYLFFFTEKILKILLKQKNEH------ 251
Query: 437 GHSSHSHGG---------HSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL-----L 482
H HSH GV +L +L P H S D A E L
Sbjct: 252 -HHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVGSL 310
Query: 483 NPEPRRLSP------------ELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATS 530
+ + + S ++ L +MITL D +HNF DGLA+GA+F S G++TS
Sbjct: 311 SVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGISTS 370
Query: 531 LAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWIL 590
+A+ C E PHELGDF LL+AG+S++QAL N SA + GL + G S S WI
Sbjct: 371 VAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG-SHFSANWIF 429
Query: 591 AVATGLFLYVALCDMLPAMLKV--RDPRPWLL---FLLHNVGLLGGWTVLLLLSLYEDDI 645
A+A G+FLY++L DM P M +V D R + F++ N+GLL G+T++++L++Y I
Sbjct: 430 ALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMVVLTMYSGQI 489
>gi|206597541 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 201 bits (512), Expect = 1e-51
Identities = 147/385 (38%), Positives = 203/385 (52%), Gaps = 22/385 (5%)
Query: 270 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRP-PVQDQLSQSERYL 328
CL+ ++ +GLS A +TP +A L PALL Q S C P P D LS L
Sbjct: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA---LL 214
Query: 329 YGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLH 388
+LA LL+ L + LLLL G R + +L +LAVG L GDA+LHL P
Sbjct: 215 QSALAVLLLSLPSPLSLLLLRLLGPR-LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGR 273
Query: 389 THSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHS- 447
GL + L++L GL+ F+ EN+ LL R L C + +
Sbjct: 274 HAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRG---LRPRCCRRKRRNLETRNL 330
Query: 448 ---HGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRL---LPYMIT 501
+G + L P + P+P +G R + ++ P L P + S + + +M+
Sbjct: 331 DPENGSGMALQPLQAA-PEPGAQGQR-EKNSQHPPALAPPGHQGHSHGHQGGTDITWMVL 388
Query: 502 LGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLL 561
LGD +HN DGLA+GAAF+ + +GL+T+LAVFCHELPHELGDFA LL +GLS R+ LLL
Sbjct: 389 LGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLL 448
Query: 562 NLASALTAFAGLYVALAVGVS---EESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPW 618
+L S G L VG+S W+ V G+FLYVAL DMLPA+L+ +P P
Sbjct: 449 SLVSGALGLGG--AVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPT 506
Query: 619 LLFLLHNVGLLGGWTVLLLLSLYED 643
LL +GLL G ++L ++L E+
Sbjct: 507 PHVLLQGLGLLLGGGLMLAITLLEE 531
>gi|206597539 solute carrier family 39 (metal ion transporter),
member 5 [Homo sapiens]
Length = 540
Score = 201 bits (512), Expect = 1e-51
Identities = 147/385 (38%), Positives = 203/385 (52%), Gaps = 22/385 (5%)
Query: 270 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRP-PVQDQLSQSERYL 328
CL+ ++ +GLS A +TP +A L PALL Q S C P P D LS L
Sbjct: 158 CLNGSQLLVNFGLSPAAPLTPRQFALLCPALLYQIDSRVCIGAPAPAPPGDLLSA---LL 214
Query: 329 YGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLH 388
+LA LL+ L + LLLL G R + +L +LAVG L GDA+LHL P
Sbjct: 215 QSALAVLLLSLPSPLSLLLLRLLGPR-LLRPLLGFLGALAVGTLCGDALLHLLPHAQEGR 273
Query: 389 THSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHS- 447
GL + L++L GL+ F+ EN+ LL R L C + +
Sbjct: 274 HAGPGGLPEKDLGPGLSVLGGLFLLFVLENMLGLLRHRG---LRPRCCRRKRRNLETRNL 330
Query: 448 ---HGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRL---LPYMIT 501
+G + L P + P+P +G R + ++ P L P + S + + +M+
Sbjct: 331 DPENGSGMALQPLQAA-PEPGAQGQR-EKNSQHPPALAPPGHQGHSHGHQGGTDITWMVL 388
Query: 502 LGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLL 561
LGD +HN DGLA+GAAF+ + +GL+T+LAVFCHELPHELGDFA LL +GLS R+ LLL
Sbjct: 389 LGDGLHNLTDGLAIGAAFSDGFSSGLSTTLAVFCHELPHELGDFAMLLQSGLSFRRLLLL 448
Query: 562 NLASALTAFAGLYVALAVGVS---EESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPW 618
+L S G L VG+S W+ V G+FLYVAL DMLPA+L+ +P P
Sbjct: 449 SLVSGALGLGG--AVLGVGLSLGPVPLTPWVFGVTAGVFLYVALVDMLPALLRPPEPLPT 506
Query: 619 LLFLLHNVGLLGGWTVLLLLSLYED 643
LL +GLL G ++L ++L E+
Sbjct: 507 PHVLLQGLGLLLGGGLMLAITLLEE 531
>gi|205830424 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 197 bits (502), Expect = 2e-50
Identities = 148/482 (30%), Positives = 230/482 (47%), Gaps = 76/482 (15%)
Query: 205 FVDFVFQQHSSEVPMTLAELSALMQRL--GVGREAHSDHSHRHRGASSRDPVPLISSSNS 262
F+ + ++ +TL +L AL+ L GVGR + H HR S+
Sbjct: 43 FLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNLST------------ 90
Query: 263 SSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLS 322
C S+ D+ A+ SEQ+ + + P +LQQ S ACTS+++ +++ +
Sbjct: 91 -------CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQT 143
Query: 323 QSER------YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHY--ILQTFLSLAVGALTG 374
+ R + YG L +I LC++ G ++ T Y +L F++LA+G L
Sbjct: 144 EEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMK---KTFYKRLLLYFIALAIGTLYS 200
Query: 375 DAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDG 434
+A+ L P+ G + + +S + + G Y FF E + +LL + E
Sbjct: 201 NALFQLIPEAFGFNPLEDYYVS-----KSAVVFGGFYLFFFTEKILKILLKQKNEH---- 251
Query: 435 PCGHSSHSHGG---------HSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL---- 481
H HSH GV +L +L P H S D A E
Sbjct: 252 ---HHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVG 308
Query: 482 -LNPEPRRLSP------------ELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLA 528
L+ + + S ++ L +MITL D +HNF DGLA+GA+F S G++
Sbjct: 309 SLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGIS 368
Query: 529 TSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAW 588
TS+A+ C E PHELGDF LL+AG+S++QAL N SA + GL + G S S W
Sbjct: 369 TSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG-SHFSANW 427
Query: 589 ILAVATGLFLYVALCDMLPAMLKV--RDPRPWLL---FLLHNVGLLGGWTVLLLLSLYED 643
I A+A G+FLY++L DM P M +V D R + F++ N+GLL G+T++++L++Y
Sbjct: 428 IFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMVVLTMYSG 487
Query: 644 DI 645
I
Sbjct: 488 QI 489
>gi|190360568 solute carrier family 39 (zinc transporter), member 14
isoform a [Homo sapiens]
Length = 492
Score = 197 bits (502), Expect = 2e-50
Identities = 148/482 (30%), Positives = 230/482 (47%), Gaps = 76/482 (15%)
Query: 205 FVDFVFQQHSSEVPMTLAELSALMQRL--GVGREAHSDHSHRHRGASSRDPVPLISSSNS 262
F+ + ++ +TL +L AL+ L GVGR + H HR S+
Sbjct: 43 FLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNLST------------ 90
Query: 263 SSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLS 322
C S+ D+ A+ SEQ+ + + P +LQQ S ACTS+++ +++ +
Sbjct: 91 -------CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQT 143
Query: 323 QSER------YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHY--ILQTFLSLAVGALTG 374
+ R + YG L +I LC++ G ++ T Y +L F++LA+G L
Sbjct: 144 EEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMK---KTFYKRLLLYFIALAIGTLYS 200
Query: 375 DAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDG 434
+A+ L P+ G + + +S + + G Y FF E + +LL + E
Sbjct: 201 NALFQLIPEAFGFNPLEDYYVS-----KSAVVFGGFYLFFFTEKILKILLKQKNEH---- 251
Query: 435 PCGHSSHSHGG---------HSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL---- 481
H HSH GV +L +L P H S D A E
Sbjct: 252 ---HHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVG 308
Query: 482 -LNPEPRRLSP------------ELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLA 528
L+ + + S ++ L +MITL D +HNF DGLA+GA+F S G++
Sbjct: 309 SLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGIS 368
Query: 529 TSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAW 588
TS+A+ C E PHELGDF LL+AG+S++QAL N SA + GL + G S S W
Sbjct: 369 TSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG-SHFSANW 427
Query: 589 ILAVATGLFLYVALCDMLPAMLKV--RDPRPWLL---FLLHNVGLLGGWTVLLLLSLYED 643
I A+A G+FLY++L DM P M +V D R + F++ N+GLL G+T++++L++Y
Sbjct: 428 IFALAGGMFLYISLADMFPEMNEVCQEDERKGSILIPFIIQNLGLLTGFTIMVVLTMYSG 487
Query: 644 DI 645
I
Sbjct: 488 QI 489
>gi|24586665 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 186 bits (473), Expect = 4e-47
Identities = 138/440 (31%), Positives = 210/440 (47%), Gaps = 59/440 (13%)
Query: 237 AHSDHSHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQL 296
A H GA+SR VP + CL+A ++ + +G S +T ++ +
Sbjct: 46 AQLQHLLEQMGAASRVGVP-----EPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVI 100
Query: 297 SPALLQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGV 356
PA+LQQ C + RP + + S SE + YG L+ +I L ++ GL+L +
Sbjct: 101 CPAVLQQLNFHPC--EDRPKHKTRPSHSEVWGYGFLSVTIINLASLLGLILTPLIK-KSY 157
Query: 357 THYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLF 416
IL F+ LA+G L +A+ L P+ G + + + +A+ G Y F F
Sbjct: 158 FPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKVDSYVE-----KAVAVFGGFYLLFFF 212
Query: 417 ENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSE-LRQPK--PPHEGSRA-- 471
E + +LL ++ GH+H + P E QPK P G
Sbjct: 213 ERMLKMLL--------------KTYGQNGHTHFGNDNFGPQEKTHQPKALPAINGVTCYA 258
Query: 472 -------------DLVAEESPELLNPEPRRLS-------PELRLLPYMITLGDAVHNFAD 511
D V+ S + EP + E+ + +MITL DA+HNF D
Sbjct: 259 NPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFID 318
Query: 512 GLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFA 571
GLA+GA+ S GL+TS+A+ C E PHELGDF LL+AG+S RQALL N SA + +
Sbjct: 319 GLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYV 378
Query: 572 GLYVALAVGVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPR------PWLLFLLHN 625
GL + VG + + I A+A G+FLY++L DM P M + + + F++ N
Sbjct: 379 GLAFGILVG-NNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQN 437
Query: 626 VGLLGGWTVLLLLSLYEDDI 645
G+L G+T +LL++LY +I
Sbjct: 438 AGMLTGFTAILLITLYAGEI 457
>gi|205830403 solute carrier family 39 (zinc transporter), member 8
isoform a [Homo sapiens]
Length = 460
Score = 186 bits (473), Expect = 4e-47
Identities = 138/440 (31%), Positives = 210/440 (47%), Gaps = 59/440 (13%)
Query: 237 AHSDHSHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQL 296
A H GA+SR VP + CL+A ++ + +G S +T ++ +
Sbjct: 46 AQLQHLLEQMGAASRVGVP-----EPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVI 100
Query: 297 SPALLQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGV 356
PA+LQQ C + RP + + S SE + YG L+ +I L ++ GL+L +
Sbjct: 101 CPAVLQQLNFHPC--EDRPKHKTRPSHSEVWGYGFLSVTIINLASLLGLILTPLIK-KSY 157
Query: 357 THYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLF 416
IL F+ LA+G L +A+ L P+ G + + + +A+ G Y F F
Sbjct: 158 FPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKVDSYVE-----KAVAVFGGFYLLFFF 212
Query: 417 ENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSE-LRQPK--PPHEGSRA-- 471
E + +LL ++ GH+H + P E QPK P G
Sbjct: 213 ERMLKMLL--------------KTYGQNGHTHFGNDNFGPQEKTHQPKALPAINGVTCYA 258
Query: 472 -------------DLVAEESPELLNPEPRRLS-------PELRLLPYMITLGDAVHNFAD 511
D V+ S + EP + E+ + +MITL DA+HNF D
Sbjct: 259 NPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFID 318
Query: 512 GLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFA 571
GLA+GA+ S GL+TS+A+ C E PHELGDF LL+AG+S RQALL N SA + +
Sbjct: 319 GLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYV 378
Query: 572 GLYVALAVGVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPR------PWLLFLLHN 625
GL + VG + + I A+A G+FLY++L DM P M + + + F++ N
Sbjct: 379 GLAFGILVG-NNFAPNIIFALAGGMFLYISLADMFPEMNDMLREKVTGRKTDFTFFMIQN 437
Query: 626 VGLLGGWTVLLLLSLYEDDI 645
G+L G+T +LL++LY +I
Sbjct: 438 AGMLTGFTAILLITLYAGEI 457
>gi|205830407 solute carrier family 39 (zinc transporter), member 8
isoform c [Homo sapiens]
Length = 393
Score = 184 bits (466), Expect = 3e-46
Identities = 130/407 (31%), Positives = 200/407 (49%), Gaps = 54/407 (13%)
Query: 270 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSERYLY 329
CL+A ++ + +G S +T ++ + PA+LQQ C + RP + + S SE + Y
Sbjct: 7 CLTAEEIFSLHGFSNATQITSSKFSVICPAVLQQLNFHPC--EDRPKHKTRPSHSEVWGY 64
Query: 330 GSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLHT 389
G L+ +I L ++ GL+L + IL F+ LA+G L +A+ L P+ G
Sbjct: 65 GFLSVTIINLASLLGLILTPLIK-KSYFPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDP 123
Query: 390 HSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHG 449
+ + + +A+ G Y F FE + +LL ++ GH+H
Sbjct: 124 KVDSYVE-----KAVAVFGGFYLLFFFERMLKMLL--------------KTYGQNGHTHF 164
Query: 450 VSLQLAPSE-LRQPK--PPHEGSRA---------------DLVAEESPELLNPEPRRLS- 490
+ P E QPK P G D V+ S + EP +
Sbjct: 165 GNDNFGPQEKTHQPKALPAINGVTCYANPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTC 224
Query: 491 ------PELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGD 544
E+ + +MITL DA+HNF DGLA+GA+ S GL+TS+A+ C E PHELGD
Sbjct: 225 LKGPKLSEIGTIAWMITLCDALHNFIDGLAIGASCTLSLLQGLSTSIAILCEEFPHELGD 284
Query: 545 FAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVALCD 604
F LL+AG+S RQALL N SA + + GL + VG + + I A+A G+FLY++L D
Sbjct: 285 FVILLNAGMSTRQALLFNFLSACSCYVGLAFGILVG-NNFAPNIIFALAGGMFLYISLAD 343
Query: 605 MLPAMLKVRDPR------PWLLFLLHNVGLLGGWTVLLLLSLYEDDI 645
M P M + + + F++ N G+L G+T +LL++LY +I
Sbjct: 344 MFPEMNDMLREKVTGRKTDFTFFMIQNAGMLTGFTAILLITLYAGEI 390
>gi|205830426 solute carrier family 39 (zinc transporter), member 14
isoform c [Homo sapiens]
Length = 481
Score = 176 bits (446), Expect = 6e-44
Identities = 133/438 (30%), Positives = 204/438 (46%), Gaps = 71/438 (16%)
Query: 205 FVDFVFQQHSSEVPMTLAELSALMQRL--GVGREAHSDHSHRHRGASSRDPVPLISSSNS 262
F+ + ++ +TL +L AL+ L GVGR + H HR S+
Sbjct: 43 FLQDLIHRYGEGDSLTLQQLKALLNHLDVGVGRGNVTQHVQGHRNLST------------ 90
Query: 263 SSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLS 322
C S+ D+ A+ SEQ+ + + P +LQQ S ACTS+++ +++ +
Sbjct: 91 -------CFSSGDLFTAHNFSEQSRIGSSELQEFCPTILQQLDSRACTSENQENEENEQT 143
Query: 323 QSER------YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHY--ILQTFLSLAVGALTG 374
+ R + YG L +I LC++ G ++ T Y +L F++LA+G L
Sbjct: 144 EEGRPSAVEVWGYGLLCVTVISLCSLLGASVVPFMK---KTFYKRLLLYFIALAIGTLYS 200
Query: 375 DAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLFENLFNLLLPRDPEDLEDG 434
+A+ L P+ G + + +S + + G Y FF E + +LL + E
Sbjct: 201 NALFQLIPEAFGFNPLEDYYVS-----KSAVVFGGFYLFFFTEKILKILLKQKNEH---- 251
Query: 435 PCGHSSHSHGG---------HSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPEL---- 481
H HSH GV +L +L P H S D A E
Sbjct: 252 ---HHGHSHYASESLPSKKDQEEGVMEKLQNGDLDHMIPQHCSSELDGKAPMVDEKVIVG 308
Query: 482 -LNPEPRRLSP------------ELRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLA 528
L+ + + S ++ L +MITL D +HNF DGLA+GA+F S G++
Sbjct: 309 SLSVQDLQASQSACYWLKGVRYSDIGTLAWMITLSDGLHNFIDGLAIGASFTVSVFQGIS 368
Query: 529 TSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAVGVSEESEAW 588
TS+A+ C E PHELGDF LL+AG+S++QAL N SA + GL + G S S W
Sbjct: 369 TSVAILCEEFPHELGDFVILLNAGMSIQQALFFNFLSACCCYLGLAFGILAG-SHFSANW 427
Query: 589 ILAVATGLFLYVALCDML 606
I A+A G+FLY++L DM+
Sbjct: 428 IFALAGGMFLYISLADMM 445
>gi|205830405 solute carrier family 39 (zinc transporter), member 8
isoform b [Homo sapiens]
Length = 444
Score = 170 bits (431), Expect = 3e-42
Identities = 127/398 (31%), Positives = 188/398 (47%), Gaps = 53/398 (13%)
Query: 237 AHSDHSHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPEAWAQL 296
A H GA+SR VP + CL+A ++ + +G S +T ++ +
Sbjct: 46 AQLQHLLEQMGAASRVGVP-----EPGQLHFNQCLTAEEIFSLHGFSNATQITSSKFSVI 100
Query: 297 SPALLQQQLSGACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGV 356
PA+LQQ C + RP + + S SE + YG L+ +I L ++ GL+L +
Sbjct: 101 CPAVLQQLNFHPC--EDRPKHKTRPSHSEVWGYGFLSVTIINLASLLGLILTPLIK-KSY 157
Query: 357 THYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEEGLSPQPTWRLLAMLAGLYAFFLF 416
IL F+ LA+G L +A+ L P+ G + + + +A+ G Y F F
Sbjct: 158 FPKILTFFVGLAIGTLFSNAIFQLIPEAFGFDPKVDSYVE-----KAVAVFGGFYLLFFF 212
Query: 417 ENLFNLLLPRDPEDLEDGPCGHSSHSHGGHSHGVSLQLAPSE-LRQPK--PPHEGSRA-- 471
E + +LL ++ GH+H + P E QPK P G
Sbjct: 213 ERMLKMLL--------------KTYGQNGHTHFGNDNFGPQEKTHQPKALPAINGVTCYA 258
Query: 472 -------------DLVAEESPELLNPEPRRLS-------PELRLLPYMITLGDAVHNFAD 511
D V+ S + EP + E+ + +MITL DA+HNF D
Sbjct: 259 NPAVTEANGHIHFDNVSVVSLQDGKKEPSSCTCLKGPKLSEIGTIAWMITLCDALHNFID 318
Query: 512 GLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFA 571
GLA+GA+ S GL+TS+A+ C E PHELGDF LL+AG+S RQALL N SA + +
Sbjct: 319 GLAIGASCTLSLLQGLSTSIAILCEEFPHELGDFVILLNAGMSTRQALLFNFLSACSCYV 378
Query: 572 GLYVALAVGVSEESEAWILAVATGLFLYVALCDMLPAM 609
GL + VG + + I A+A G+FLY++L DM P M
Sbjct: 379 GLAFGILVG-NNFAPNIIFALAGGMFLYISLADMFPEM 415
>gi|187936949 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 161 bits (407), Expect = 2e-39
Identities = 93/214 (43%), Positives = 126/214 (58%), Gaps = 38/214 (17%)
Query: 441 HSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMI 500
H H HSHG P H GS DL + + N + +M+
Sbjct: 645 HKHSHHSHG--------------PCHSGS--DL---KETGIAN------------IAWMV 673
Query: 501 TLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALL 560
+GD +HNF+DGLA+GAAF++ G++TS+AVFCHELPHELGDFA LL AG++V+QA++
Sbjct: 674 IMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIV 733
Query: 561 LNLASALTAFAGLYVALAVG-VSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPR--- 616
NL SA+ A+ G+ + AVG + WI AV G+FLYVAL DMLP ML
Sbjct: 734 YNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEH 793
Query: 617 ---PWLLFLLHNVGLLGGWTVLLLLSLYEDDITF 647
P F+L N+GLL G+ ++L+++LYED I F
Sbjct: 794 GFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVF 827
Score = 55.1 bits (131), Expect = 2e-07
Identities = 34/137 (24%), Positives = 67/137 (48%), Gaps = 14/137 (10%)
Query: 270 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSER--- 326
CL+ ++ YG + ++ + + L PALL Q S C + + +++ +
Sbjct: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
Query: 327 ----------YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDA 376
++ G ++ +I L ++ G++L+ +G ++L ++LAVG ++GDA
Sbjct: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIIN-QGCFKFLLTFLVALAVGTMSGDA 455
Query: 377 VLHLTPKVLGLHTHSEE 393
+LHL P G H HS +
Sbjct: 456 LLHLLPHSQGGHDHSHQ 472
>gi|55741750 solute carrier family 39 (zinc transporter), member 10
[Homo sapiens]
Length = 831
Score = 161 bits (407), Expect = 2e-39
Identities = 93/214 (43%), Positives = 126/214 (58%), Gaps = 38/214 (17%)
Query: 441 HSHGGHSHGVSLQLAPSELRQPKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMI 500
H H HSHG P H GS DL + + N + +M+
Sbjct: 645 HKHSHHSHG--------------PCHSGS--DL---KETGIAN------------IAWMV 673
Query: 501 TLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALL 560
+GD +HNF+DGLA+GAAF++ G++TS+AVFCHELPHELGDFA LL AG++V+QA++
Sbjct: 674 IMGDGIHNFSDGLAIGAAFSAGLTGGISTSIAVFCHELPHELGDFAVLLKAGMTVKQAIV 733
Query: 561 LNLASALTAFAGLYVALAVG-VSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPR--- 616
NL SA+ A+ G+ + AVG + WI AV G+FLYVAL DMLP ML
Sbjct: 734 YNLLSAMMAYIGMLIGTAVGQYANNITLWIFAVTAGMFLYVALVDMLPEMLHGDGDNEEH 793
Query: 617 ---PWLLFLLHNVGLLGGWTVLLLLSLYEDDITF 647
P F+L N+GLL G+ ++L+++LYED I F
Sbjct: 794 GFCPVGQFILQNLGLLFGFAIMLVIALYEDKIVF 827
Score = 55.1 bits (131), Expect = 2e-07
Identities = 34/137 (24%), Positives = 67/137 (48%), Gaps = 14/137 (10%)
Query: 270 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQSRPPVQDQLSQSER--- 326
CL+ ++ YG + ++ + + L PALL Q S C + + +++ +
Sbjct: 337 CLNVTQLLKYYGHGANSPISTDLFTYLCPALLYQIDSRLCIEHFDKLLVEDINKDKNLVP 396
Query: 327 ----------YLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDA 376
++ G ++ +I L ++ G++L+ +G ++L ++LAVG ++GDA
Sbjct: 397 EDEANIGASAWICGIISITVISLLSLLGVILVPIIN-QGCFKFLLTFLVALAVGTMSGDA 455
Query: 377 VLHLTPKVLGLHTHSEE 393
+LHL P G H HS +
Sbjct: 456 LLHLLPHSQGGHDHSHQ 472
>gi|153252201 solute carrier family 39 (zinc transporter), member 6
isoform 1 [Homo sapiens]
Length = 755
Score = 154 bits (390), Expect = 2e-37
Identities = 77/157 (49%), Positives = 106/157 (67%), Gaps = 5/157 (3%)
Query: 496 LPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSV 555
L +M+ +GD +HNF+DGLA+GAAF +GL+TS+AVFCHELPHELGDFA LL AG++V
Sbjct: 595 LAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTV 654
Query: 556 RQALLLNLASALTAFAGLYVALAVG-VSEESEAWILAVATGLFLYVALCDMLPAML---- 610
+QA+L N SA+ A+ G+ + +G +E WI A+ GLF+YVAL DM+P ML
Sbjct: 655 KQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMVPEMLHNDA 714
Query: 611 KVRDPRPWLLFLLHNVGLLGGWTVLLLLSLYEDDITF 647
W F L N G+L G+ ++LL+S++E I F
Sbjct: 715 SDHGCSRWGYFFLQNAGMLLGFGIMLLISIFEHKIVF 751
Score = 60.5 bits (145), Expect = 5e-09
Identities = 47/182 (25%), Positives = 81/182 (44%), Gaps = 29/182 (15%)
Query: 270 CLSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGAC---TSQSRPPVQDQL-SQSE 325
C +A ++ ++G+ Q + + L PA++ Q + +C TS+ + + + S
Sbjct: 264 CFNASKLLTSHGMGIQVPLNATEFNYLCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQI 323
Query: 326 RYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVL 385
++ G +A +I ++ G++L+ R ++L ++LAVG L+GDA LHL P
Sbjct: 324 AWVGGFIAISIISFLSLLGVILVPLMN-RVFFKFLLSFLVALAVGTLSGDAFLHLLPHSH 382
Query: 386 GLHTHS------------------------EEGLSPQPTWRLLAMLAGLYAFFLFENLFN 421
H HS EE TW+ L L GLY FL E++
Sbjct: 383 ASHHHSHSHEEPAMEMKRGPLFSHLSSQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLT 442
Query: 422 LL 423
L+
Sbjct: 443 LI 444
>gi|117553619 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 146 bits (369), Expect = 5e-35
Identities = 116/368 (31%), Positives = 165/368 (44%), Gaps = 45/368 (12%)
Query: 307 GACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLS 366
G P ++ L + Y AT+LI F L L+ +LQ LS
Sbjct: 115 GGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLS 174
Query: 367 LAVGALTGDAVLHLTPKVLGLHTH----------SEEGLSPQPTWRLLAMLAGLYAFFLF 416
A G L GDA LHL P L H+H S G P + L +L+G+ AF +
Sbjct: 175 FASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLW-VLSGIVAFLVV 233
Query: 417 ENLFNLLLPRDPEDLEDGPCGHS-------SHSHGGHSHG------VSLQLAPSELRQPK 463
E + G GHS SH+ G H HG Q + E ++ +
Sbjct: 234 EKFVRHV---------KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETR 284
Query: 464 PPHEGSRADLVAEESP-ELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASS 522
+ V ++ P N E + +LR+ Y+ D HNF DGLA+GA+F
Sbjct: 285 GVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGG 344
Query: 523 WKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVAL----- 577
G+ T++ V HE+PHE+GDFA L+ +G S +QA+ L L +A+ A AG AL
Sbjct: 345 RGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGG 404
Query: 578 AVG---VSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTV 634
AVG W+L G F+YVA +LP +L+ P L LL +GLLGG +
Sbjct: 405 AVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASP---LQSLLEVLGLLGGVIM 461
Query: 635 LLLLSLYE 642
++L++ E
Sbjct: 462 MVLIAHLE 469
>gi|117553608 solute carrier family 39, member 7 [Homo sapiens]
Length = 469
Score = 146 bits (369), Expect = 5e-35
Identities = 116/368 (31%), Positives = 165/368 (44%), Gaps = 45/368 (12%)
Query: 307 GACTSQSRPPVQDQLSQSERYLYGSLATLLICLCAVFGLLLLTCTGCRGVTHYILQTFLS 366
G P ++ L + Y AT+LI F L L+ +LQ LS
Sbjct: 115 GGYGESGAPGIKQDLDAVTLWAYALGATVLISAAPFFVLFLIPVESNSPRHRSLLQILLS 174
Query: 367 LAVGALTGDAVLHLTPKVLGLHTH----------SEEGLSPQPTWRLLAMLAGLYAFFLF 416
A G L GDA LHL P L H+H S G P + L +L+G+ AF +
Sbjct: 175 FASGGLLGDAFLHLIPHALEPHSHHTLEQPGHGHSHSGQGPILSVGLW-VLSGIVAFLVV 233
Query: 417 ENLFNLLLPRDPEDLEDGPCGHS-------SHSHGGHSHG------VSLQLAPSELRQPK 463
E + G GHS SH+ G H HG Q + E ++ +
Sbjct: 234 EKFVRHV---------KGGHGHSHGHGHAHSHTRGSHGHGRQERSTKEKQSSEEEEKETR 284
Query: 464 PPHEGSRADLVAEESP-ELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFASS 522
+ V ++ P N E + +LR+ Y+ D HNF DGLA+GA+F
Sbjct: 285 GVQKRRGGSTVPKDGPVRPQNAEEEKRGLDLRVSGYLNLAADLAHNFTDGLAIGASFRGG 344
Query: 523 WKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVAL----- 577
G+ T++ V HE+PHE+GDFA L+ +G S +QA+ L L +A+ A AG AL
Sbjct: 345 RGLGILTTMTVLLHEVPHEVGDFAILVQSGCSKKQAMRLQLLTAVGALAGTACALLTEGG 404
Query: 578 AVG---VSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTV 634
AVG W+L G F+YVA +LP +L+ P L LL +GLLGG +
Sbjct: 405 AVGSEIAGGAGPGWVLPFTAGGFIYVATVSVLPELLREASP---LQSLLEVLGLLGGVIM 461
Query: 635 LLLLSLYE 642
++L++ E
Sbjct: 462 MVLIAHLE 469
>gi|153252214 solute carrier family 39 (zinc transporter), member 6
isoform 2 [Homo sapiens]
Length = 433
Score = 130 bits (328), Expect = 3e-30
Identities = 61/112 (54%), Positives = 83/112 (74%), Gaps = 1/112 (0%)
Query: 496 LPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAGLSV 555
L +M+ +GD +HNF+DGLA+GAAF +GL+TS+AVFCHELPHELGDFA LL AG++V
Sbjct: 320 LAWMVIMGDGLHNFSDGLAIGAAFTEGLSSGLSTSVAVFCHELPHELGDFAVLLKAGMTV 379
Query: 556 RQALLLNLASALTAFAGLYVALAVG-VSEESEAWILAVATGLFLYVALCDML 606
+QA+L N SA+ A+ G+ + +G +E WI A+ GLF+YVAL DM+
Sbjct: 380 KQAVLYNALSAMLAYLGMATGIFIGHYAENVSMWIFALTAGLFMYVALVDMV 431
Score = 52.0 bits (123), Expect = 2e-06
Identities = 43/156 (27%), Positives = 69/156 (44%), Gaps = 29/156 (18%)
Query: 296 LSPALLQQQLSGAC---TSQSRPPVQDQL-SQSERYLYGSLATLLICLCAVFGLLLLTCT 351
L PA++ Q + +C TS+ + + + S ++ G +A +I ++ G++L+
Sbjct: 15 LCPAIINQIDARSCLIHTSEKKAEIPPKTYSLQIAWVGGFIAISIISFLSLLGVILVPLM 74
Query: 352 GCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHS-------------------- 391
R ++L ++LAVG L+GDA LHL P H HS
Sbjct: 75 N-RVFFKFLLSFLVALAVGTLSGDAFLHLLPHSHASHHHSHSHEEPAMEMKRGPLFSHLS 133
Query: 392 ----EEGLSPQPTWRLLAMLAGLYAFFLFENLFNLL 423
EE TW+ L L GLY FL E++ L+
Sbjct: 134 SQNIEESAYFDSTWKGLTALGGLYFMFLVEHVLTLI 169
>gi|40255101 solute carrier family 39 (zinc transporter), member 13
isoform b [Homo sapiens]
Length = 364
Score = 116 bits (291), Expect = 6e-26
Identities = 113/366 (30%), Positives = 165/366 (45%), Gaps = 56/366 (15%)
Query: 298 PALLQQQLSGACTSQSRPPVQ-DQLSQSER---YLYGSLATLLICLCAVFGLLLLTC--- 350
PAL + + AC ++ L ER ++ L +L++ L VF LL++
Sbjct: 35 PALRSRGTATACRLDNKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMG 94
Query: 351 TGCRGVTH-YILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSE---EGLSPQPTWRL-LA 405
T R + L+ LS A+G L G+ LHL P+ + EG S Q +L L
Sbjct: 95 TMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLW 154
Query: 406 MLAGLYAFFLFENLFNLLLPRDPEDLEDGP----CGHSSHSHGGHSHGVSLQLAPSELRQ 461
++AG+ F E +F L E P ++ +GGH L Q
Sbjct: 155 VIAGILTFLALEKMF---LDSKEEGTSQAPNKDPTAAAAALNGGHC-----------LAQ 200
Query: 462 PKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFAS 521
P P + +++ Y+ L + + NF GLAV A+F
Sbjct: 201 PAA------------------EPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASFLV 242
Query: 522 SWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVALAV-- 579
S K GL T++A+ HE+PHE+GDFA LL AG A L L++AL G A+
Sbjct: 243 SKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQS 302
Query: 580 --GVSEESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGGWTVLLL 637
GV EE+ AW+L +G FLY+AL ++LP +L+ DP L LL L G V++L
Sbjct: 303 PKGV-EETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLL---LCAGIVVMVL 358
Query: 638 LSLYED 643
SL+ D
Sbjct: 359 FSLFVD 364
>gi|190014617 solute carrier family 39 (zinc transporter), member 13
isoform a [Homo sapiens]
Length = 371
Score = 115 bits (289), Expect = 1e-25
Identities = 114/372 (30%), Positives = 166/372 (44%), Gaps = 61/372 (16%)
Query: 298 PALLQQQLSGACTSQSRPPVQ-DQLSQSER---YLYGSLATLLICLCAVFGLLLLTC--- 350
PAL + + AC ++ L ER ++ L +L++ L VF LL++
Sbjct: 35 PALRSRGTATACRLDNKESESWGALLSGERLDTWICSLLGSLMVGLSGVFPLLVIPLEMG 94
Query: 351 TGCRGVTH-YILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSE---EGLSPQPTWRL-LA 405
T R + L+ LS A+G L G+ LHL P+ + EG S Q +L L
Sbjct: 95 TMLRSEAGAWRLKQLLSFALGGLLGNVFLHLLPEAWAYTCSASPGGEGQSLQQQQQLGLW 154
Query: 406 MLAGLYAFFLFENLFNLLLPRDPEDLEDGP----CGHSSHSHGGHSHGVSLQLAPSELRQ 461
++AG+ F E +F L E P ++ +GGH L Q
Sbjct: 155 VIAGILTFLALEKMF---LDSKEEGTSQAPNKDPTAAAAALNGGHC-----------LAQ 200
Query: 462 PKPPHEGSRADLVAEESPELLNPEPRRLSPELRLLPYMITLGDAVHNFADGLAVGAAFAS 521
P P + +++ Y+ L + + NF GLAV A+F
Sbjct: 201 PAA------------------EPGLGAVVRSIKVSGYLNLLANTIDNFTHGLAVAASFLV 242
Query: 522 SWKTGLATSLAVFCHELPHELGDFAALLHAGLSVRQALLLNLASALTAFAGLYVAL---- 577
S K GL T++A+ HE+PHE+GDFA LL AG A L L++AL G A+
Sbjct: 243 SKKIGLLTTMAILLHEIPHEVGDFAILLRAGFDRWSAAKLQLSTALGGLLGAGFAICTQS 302
Query: 578 ---AVGVS---EESEAWILAVATGLFLYVALCDMLPAMLKVRDPRPWLLFLLHNVGLLGG 631
VG S EE+ AW+L +G FLY+AL ++LP +L+ DP L LL L G
Sbjct: 303 PKGVVGCSPAAEETAAWVLPFTSGGFLYIALVNVLPDLLEEEDPWRSLQQLLL---LCAG 359
Query: 632 WTVLLLLSLYED 643
V++L SL+ D
Sbjct: 360 IVVMVLFSLFVD 371
>gi|40254928 solute carrier family 39 (zinc transporter), member 9
[Homo sapiens]
Length = 307
Score = 51.2 bits (121), Expect = 3e-06
Identities = 39/116 (33%), Positives = 61/116 (52%), Gaps = 9/116 (7%)
Query: 501 TLGDAVHNFADGLAVGAAFASS-WKTGLATSLAVFCHELPHELGDFAALLHAGLS---VR 556
TLG VH ADG+A+GAA ++S L +A+ H+ P G + L+HAGL +R
Sbjct: 149 TLGLVVHAAADGVALGAAASTSQTSVQLIVFVAIMLHKAPAAFGLVSFLMHAGLERNRIR 208
Query: 557 QALLLNLASA----LTAFAGLYVALAVGVSEESEAWI-LAVATGLFLYVALCDMLP 607
+ LL+ +A + + GL + +SE + + + + G FLYVA +LP
Sbjct: 209 KHLLVFALAAPVMSMVTYLGLSKSSKEALSEVNATGVAMLFSAGTFLYVATVHVLP 264
>gi|229577422 solute carrier family 39, member 11 isoform 1 [Homo
sapiens]
Length = 342
Score = 50.1 bits (118), Expect = 6e-06
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 8/117 (6%)
Query: 499 MITLGDAVHNFADGLAVGAAFASSWKTGLAT-------SLAVFCHELPHELGDFAALLHA 551
++ L +HN +GLAVG F + KT AT ++ + P L L A
Sbjct: 196 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 255
Query: 552 GLSVRQALLLN-LASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVALCDMLP 607
G S +A L+ + AG++ A AV ++E + LA A G +YV + D++P
Sbjct: 256 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIP 312
>gi|229577418 solute carrier family 39, member 11 isoform 2 [Homo
sapiens]
Length = 335
Score = 50.1 bits (118), Expect = 6e-06
Identities = 35/117 (29%), Positives = 55/117 (47%), Gaps = 8/117 (6%)
Query: 499 MITLGDAVHNFADGLAVGAAFASSWKTGLAT-------SLAVFCHELPHELGDFAALLHA 551
++ L +HN +GLAVG F + KT AT ++ + P L L A
Sbjct: 189 LLILAITIHNVPEGLAVGVGFGAIEKTASATFESARNLAIGIGIQNFPEGLAVSLPLRGA 248
Query: 552 GLSVRQALLLN-LASALTAFAGLYVALAVGVSEESEAWILAVATGLFLYVALCDMLP 607
G S +A L+ + AG++ A AV ++E + LA A G +YV + D++P
Sbjct: 249 GFSTWRAFWYGQLSGMVEPLAGVFGAFAVVLAEPILPYALAFAAGAMVYVVMDDIIP 305
>gi|156415986 solute carrier family 39 (zinc transporter), member 2
[Homo sapiens]
Length = 309
Score = 45.1 bits (105), Expect = 2e-04
Identities = 45/124 (36%), Positives = 61/124 (49%), Gaps = 10/124 (8%)
Query: 493 LRLLPYMITLGDAVHNFADGLAVGAAFASSWKTGLATSLAVFCHELPHELGDFAALLHAG 552
LR L +++L + H+ +GLAVG + L LAV H+ G L+H G
Sbjct: 163 LRALVLLLSL--SFHSVFEGLAVGLQPTVAATVQLC--LAVLAHKGLVVFGVGMRLVHLG 218
Query: 553 LSVRQALLLNLASALTAFAGLYVALAV--GVSEE----SEAWILAVATGLFLYVALCDML 606
S R A+ L AL + GL V LAV G SE ++A + VA G FLYV ++L
Sbjct: 219 TSSRWAVFSILLLALMSPLGLAVGLAVTGGDSEGGRGLAQAVLEGVAAGTFLYVTFLEIL 278
Query: 607 PAML 610
P L
Sbjct: 279 PREL 282
>gi|34365793 WNK lysine deficient protein kinase 4 [Homo sapiens]
Length = 1243
Score = 33.1 bits (74), Expect = 0.82
Identities = 31/103 (30%), Positives = 44/103 (42%), Gaps = 18/103 (17%)
Query: 216 EVPMTLAELSALMQRLGVGREAHSDHSHRHRGASSRDPVPLISSSNSSSVW-----DTVC 270
E LAE + LG G E D + S P+ S+ S VW ++C
Sbjct: 1065 ETREALAESDRAAEGLGAGVEEEGDDGKEPQVGGSPQPL-----SHPSPVWMNYSYSSLC 1119
Query: 271 LSARDVMAAYGLSEQAGVTPEAWAQLSPALLQQQLSGACTSQS 313
LS+ + SE +G E WA+L +L Q+ LS T Q+
Sbjct: 1120 LSSEE-------SESSGEDEEFWAELQ-SLRQKHLSEVETLQT 1154
>gi|239741896 PREDICTED: hypothetical protein XP_002342335 [Homo
sapiens]
Length = 347
Score = 33.1 bits (74), Expect = 0.82
Identities = 20/61 (32%), Positives = 29/61 (47%), Gaps = 2/61 (3%)
Query: 232 GVGREAHSDHSHRHRGASSRDPVPLISSSNSSSVWDTVCLSARDVMAAYGLSEQAGVTPE 291
G+ ++H +H H+GAS PL S+ VW + CL+ +G EQ PE
Sbjct: 285 GLRIQSHPGTTHLHQGASFTSSEPLSGISSPRGVWASGCLAPFPQPLIHG--EQRRALPE 342
Query: 292 A 292
A
Sbjct: 343 A 343
>gi|41352721 solute carrier family 36 member 1 [Homo sapiens]
Length = 476
Score = 32.0 bits (71), Expect = 1.8
Identities = 26/106 (24%), Positives = 49/106 (46%), Gaps = 15/106 (14%)
Query: 334 TLLICLCAVFGLLLLTCTGCRGVTHYILQTFLSLAVGALTGDAVLHLTPKVLGLHTHSEE 393
T+L+CL + +L+ L +SL VG+++ A+ + P +L + T E
Sbjct: 380 TVLVCLTCILAILIPR-----------LDLVISL-VGSVSSSALALIIPPLLEVTTFYSE 427
Query: 394 GLSPQPTWR-LLAMLAGLYAFFL--FENLFNLLLPRDPEDLEDGPC 436
G+SP ++ L + G F + +E L+ L+ P + + C
Sbjct: 428 GMSPLTIFKDALISILGFVGFVVGTYEALYELIQPSNAPIFINSTC 473
>gi|30794216 tripartite motif-containing 56 [Homo sapiens]
Length = 755
Score = 31.2 bits (69), Expect = 3.1
Identities = 22/56 (39%), Positives = 26/56 (46%), Gaps = 1/56 (1%)
Query: 77 PEGSGLPPGPVLEARYVARLSAAAVLYLSNPEGTCEDARAGLWASHADHLLALLES 132
P G P V + SA+A LYL NP G + RA L S A H +A L S
Sbjct: 545 PVPEGCSPCSVAALQSAVAFSASARLYLINPNGEVQWRRA-LSLSQASHAVAALPS 599
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.320 0.135 0.410
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 26,983,280
Number of Sequences: 37866
Number of extensions: 1339351
Number of successful extensions: 3993
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 28
Number of HSP's successfully gapped in prelim test: 18
Number of HSP's that attempted gapping in prelim test: 3858
Number of HSP's gapped (non-prelim): 77
length of query: 647
length of database: 18,247,518
effective HSP length: 109
effective length of query: 538
effective length of database: 14,120,124
effective search space: 7596626712
effective search space used: 7596626712
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.