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Search of human proteins with 223718134
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|223718134 cyclin-dependent kinase 6 [Homo sapiens]
(326 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|223718134 cyclin-dependent kinase 6 [Homo sapiens] 657 0.0
gi|4502741 cyclin-dependent kinase 6 [Homo sapiens] 657 0.0
gi|4502735 cyclin-dependent kinase 4 [Homo sapiens] 419 e-117
gi|4557439 cyclin-dependent kinase 3 [Homo sapiens] 272 3e-73
gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens] 268 5e-72
gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens] 259 3e-69
gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens] 257 1e-68
gi|4826675 cyclin-dependent kinase 5 [Homo sapiens] 239 3e-63
gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isof... 229 3e-60
gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isof... 229 3e-60
gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isof... 229 3e-60
gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isof... 229 3e-60
gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isof... 229 3e-60
gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isof... 229 3e-60
gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens] 226 2e-59
gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens] 226 2e-59
gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens] 218 6e-57
gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens] 211 7e-55
gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 211 7e-55
gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens] 211 7e-55
gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens] 209 2e-54
gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens] 209 2e-54
gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens] 209 2e-54
gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens] 207 1e-53
gi|21040235 PFTAIRE protein kinase 2 [Homo sapiens] 195 5e-50
gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2... 194 9e-50
gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1... 194 9e-50
gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens] 192 3e-49
gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens] 192 3e-49
gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens] 191 8e-49
>gi|223718134 cyclin-dependent kinase 6 [Homo sapiens]
Length = 326
Score = 657 bits (1695), Expect = 0.0
Identities = 326/326 (100%), Positives = 326/326 (100%)
Query: 1 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR 60
MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
Sbjct: 1 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR 60
Query: 61 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE 120
EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
Sbjct: 61 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE 120
Query: 121 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV 180
TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
Sbjct: 121 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV 180
Query: 181 VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE 240
VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
Sbjct: 181 VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE 240
Query: 241 EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF 300
EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
Sbjct: 241 EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF 300
Query: 301 QDLERCKENLDSHLPPSQNTSELNTA 326
QDLERCKENLDSHLPPSQNTSELNTA
Sbjct: 301 QDLERCKENLDSHLPPSQNTSELNTA 326
>gi|4502741 cyclin-dependent kinase 6 [Homo sapiens]
Length = 326
Score = 657 bits (1695), Expect = 0.0
Identities = 326/326 (100%), Positives = 326/326 (100%)
Query: 1 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR 60
MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR
Sbjct: 1 MEKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIR 60
Query: 61 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE 120
EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE
Sbjct: 61 EVAVLRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTE 120
Query: 121 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV 180
TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV
Sbjct: 121 TIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVV 180
Query: 181 VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE 240
VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE
Sbjct: 181 VTLWYRAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGE 240
Query: 241 EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF 300
EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF
Sbjct: 241 EDWPRDVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF 300
Query: 301 QDLERCKENLDSHLPPSQNTSELNTA 326
QDLERCKENLDSHLPPSQNTSELNTA
Sbjct: 301 QDLERCKENLDSHLPPSQNTSELNTA 326
>gi|4502735 cyclin-dependent kinase 4 [Homo sapiens]
Length = 303
Score = 419 bits (1077), Expect = e-117
Identities = 209/294 (71%), Positives = 241/294 (81%), Gaps = 4/294 (1%)
Query: 9 ADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEG---MPLSTIREVAVL 65
A +YE VAEIG GAYG V+KARD + G FVALK VRV G G +P+ST+REVA+L
Sbjct: 2 ATSRYEPVAEIGVGAYGTVYKARD-PHSGHFVALKSVRVPNGGGGGGGLPISTVREVALL 60
Query: 66 RHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDM 125
R LE FEHPNVVRL DVC SRTDRE K+TLVFEHVDQDL TYLDK P PG+P ETIKD+
Sbjct: 61 RRLEAFEHPNVVRLMDVCATSRTDREIKVTLVFEHVDQDLRTYLDKAPPPGLPAETIKDL 120
Query: 126 MFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSVVVTLWY 185
M Q LRGLDFLH++ +VHRDLKP+NILVTS G +KLADFGLARIYS+QMALT VVVTLWY
Sbjct: 121 MRQFLRGLDFLHANCIVHRDLKPENILVTSGGTVKLADFGLARIYSYQMALTPVVVTLWY 180
Query: 186 RAPEVLLQSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPR 245
RAPEVLLQS+YATPVD+WSVGCIFAEMFRRKPLF G+S+ DQLGKI D+IGLP E+DWPR
Sbjct: 181 RAPEVLLQSTYATPVDMWSVGCIFAEMFRRKPLFCGNSEADQLGKIFDLIGLPPEDDWPR 240
Query: 246 DVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPY 299
DV+LPR AF + +P++ V +++E G LLL+ LTFNP KRISA+ AL H Y
Sbjct: 241 DVSLPRGAFPPRGPRPVQSVVPEMEESGAQLLLEMLTFNPHKRISAFRALQHSY 294
>gi|4557439 cyclin-dependent kinase 3 [Homo sapiens]
Length = 305
Score = 272 bits (695), Expect = 3e-73
Identities = 142/296 (47%), Positives = 200/296 (67%), Gaps = 13/296 (4%)
Query: 13 YECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFE 72
++ V +IGEG YG V+KA++ + G+ VALK++R+ EG+P + IRE+++L+ L+
Sbjct: 4 FQKVEKIGEGTYGVVYKAKN-RETGQLVALKKIRLDLEMEGVPSTAIREISLLKELK--- 59
Query: 73 HPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRG 132
HPN+VRL DV E KL LVFE + QDL Y+D P +P IK +FQLL+G
Sbjct: 60 HPNIVRLLDV-----VHNERKLYLVFEFLSQDLKKYMDSTPGSELPLHLIKSYLFQLLQG 114
Query: 133 LDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWYRAPEVL 191
+ F HSHRV+HRDLKPQN+L+ G IKLADFGLAR + + T VVTLWYRAPE+L
Sbjct: 115 VSFCHSHRVIHRDLKPQNLLINELGAIKLADFGLARAFGVPLRTYTHEVVTLWYRAPEIL 174
Query: 192 LQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVALP 250
L S Y T VD+WS+GCIFAEM RK LF G S++DQL +I ++G P E+ WP LP
Sbjct: 175 LGSKFYTTAVDIWSIGCIFAEMVTRKALFPGDSEIDQLFRIFRMLGTPSEDTWPGVTQLP 234
Query: 251 --RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLE 304
+ +F + + +E+ V +++ G+DLL++ L ++P++RI+A +AL+HPYF E
Sbjct: 235 DYKGSFPKWTRKGLEEIVPNLEPEGRDLLMQLLQYDPSQRITAKTALAHPYFSSPE 290
>gi|16936528 cyclin-dependent kinase 2 isoform 1 [Homo sapiens]
Length = 298
Score = 268 bits (685), Expect = 5e-72
Identities = 145/299 (48%), Positives = 198/299 (66%), Gaps = 13/299 (4%)
Query: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
+ ++ V +IGEG YG V+KAR+ K G VALK++R+ T EG+P + IRE+++L+ L
Sbjct: 2 ENFQKVEKIGEGTYGVVYKARN-KLTGEVVALKKIRLDTETEGVPSTAIREISLLKELN- 59
Query: 71 FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLL 130
HPN+V+L DV E KL LVFE + QDL ++D G+P IK +FQLL
Sbjct: 60 --HPNIVKLLDVIHT-----ENKLYLVFEFLHQDLKKFMDASALTGIPLPLIKSYLFQLL 112
Query: 131 RGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWYRAPE 189
+GL F HSHRV+HRDLKPQN+L+ + G IKLADFGLAR + + T VVTLWYRAPE
Sbjct: 113 QGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPE 172
Query: 190 VLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVA 248
+LL Y+T VD+WS+GCIFAEM R+ LF G S++DQL +I +G P E WP +
Sbjct: 173 ILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTS 232
Query: 249 LP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLER 305
+P + +F + Q K V +DE G+ LL + L ++P KRISA +AL+HP+FQD+ +
Sbjct: 233 MPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFFQDVTK 291
>gi|4502709 cell division cycle 2 isoform 1 [Homo sapiens]
Length = 297
Score = 259 bits (661), Expect = 3e-69
Identities = 139/300 (46%), Positives = 198/300 (66%), Gaps = 16/300 (5%)
Query: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
+ Y + +IGEG YG V+K R K G+ VA+K++R+++ EEG+P + IRE+++L+ L
Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELR- 59
Query: 71 FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPG--VPTETIKDMMFQ 128
HPN+V L DV ++++L L+FE + DL YLD +P PG + + +K ++Q
Sbjct: 60 --HPNIVSLQDVLM-----QDSRLYLIFEFLSMDLKKYLDSIP-PGQYMDSSLVKSYLYQ 111
Query: 129 LLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMAL-TSVVVTLWYRA 187
+L+G+ F HS RV+HRDLKPQN+L+ G IKLADFGLAR + + + T VVTLWYR+
Sbjct: 112 ILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEVVTLWYRS 171
Query: 188 PEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRD 246
PEVLL S+ Y+TPVD+WS+G IFAE+ +KPLF G S++DQL +I +G P E WP
Sbjct: 172 PEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEV 231
Query: 247 VALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLE 304
+L + F + V ++DE G DLL K L ++PAKRIS AL+HPYF DL+
Sbjct: 232 ESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 291
>gi|195927041 cell division cycle 2 isoform 3 [Homo sapiens]
Length = 297
Score = 257 bits (656), Expect = 1e-68
Identities = 137/300 (45%), Positives = 197/300 (65%), Gaps = 16/300 (5%)
Query: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
+ Y + +IGEG YG V+K R K G+ VA+K++R+++ EEG+P + IRE+++L+ L
Sbjct: 2 EDYTKIEKIGEGTYGVVYKGRH-KTTGQVVAMKKIRLESEEEGVPSTAIREISLLKELR- 59
Query: 71 FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPG--VPTETIKDMMFQ 128
HPN+V L DV ++++L L+FE + DL YLD +P PG + + +K ++Q
Sbjct: 60 --HPNIVSLQDVLM-----QDSRLYLIFEFLSMDLKKYLDSIP-PGQYMDSSLVKSYLYQ 111
Query: 129 LLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMAL-TSVVVTLWYRA 187
+L+G+ F HS RV+HRDLKPQN+L+ G IKLADFGLAR + + + T +TLWYR+
Sbjct: 112 ILQGIVFCHSRRVLHRDLKPQNLLIDDKGTIKLADFGLARAFGIPIRVYTHEAITLWYRS 171
Query: 188 PEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRD 246
PEVLL S+ Y+TPVD+WS+G IFAE+ +KPLF G S++DQL +I +G P E WP
Sbjct: 172 PEVLLGSARYSTPVDIWSIGTIFAELATKKPLFHGDSEIDQLFRIFRALGTPNNEVWPEV 231
Query: 247 VALP--RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDLE 304
+L + F + V ++DE G DLL K L ++PAKRIS AL+HPYF DL+
Sbjct: 232 ESLQDYKNTFPKWKPGSLASHVKNLDENGLDLLSKMLIYDPAKRISGKMALNHPYFNDLD 291
>gi|4826675 cyclin-dependent kinase 5 [Homo sapiens]
Length = 292
Score = 239 bits (609), Expect = 3e-63
Identities = 136/297 (45%), Positives = 182/297 (61%), Gaps = 15/297 (5%)
Query: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
Q+YE + +IGEG YG VFKA++ + VALKRVR+ +EG+P S +RE+ +L+ L+
Sbjct: 2 QKYEKLEKIGEGTYGTVFKAKN-RETHEIVALKRVRLDDDDEGVPSSALREICLLKELK- 59
Query: 71 FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLL 130
H N+VRL DV + KLTLVFE DQDL Y D + E +K +FQLL
Sbjct: 60 --HKNIVRLHDVL-----HSDKKLTLVFEFCDQDLKKYFDSC-NGDLDPEIVKSFLFQLL 111
Query: 131 RGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMALTSV-VVTLWYRAPE 189
+GL F HS V+HRDLKPQN+L+ +G++KLADFGLAR + + S VVTLWYR P+
Sbjct: 112 KGLGFCHSRNVLHRDLKPQNLLINRNGELKLADFGLARAFGIPVRCYSAEVVTLWYRPPD 171
Query: 190 VLLQSS-YATPVDLWSVGCIFAEMFRR-KPLFRGSSDVDQLGKILDVIGLPGEEDWPRDV 247
VL + Y+T +D+WS GCIFAE+ +PLF G+ DQL +I ++G P EE WP
Sbjct: 172 VLFGAKLYSTSIDMWSAGCIFAELANAGRPLFPGNDVDDQLKRIFRLLGTPTEEQWPSMT 231
Query: 248 ALPRQAFHS--KSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQD 302
LP + + + V ++ G+DLL L NP +RISA AL HPYF D
Sbjct: 232 KLPDYKPYPMYPATTSLVNVVPKLNATGRDLLQNLLKCNPVQRISAEEALQHPYFSD 288
>gi|16332372 cell division cycle 2-like 1 (PITSLRE proteins) isoform
9 [Homo sapiens]
Length = 771
Score = 229 bits (583), Expect = 3e-60
Identities = 122/302 (40%), Positives = 192/302 (63%), Gaps = 14/302 (4%)
Query: 7 CRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLR 66
CR+ ++++C+ I EG YG V++A+D K VALKR++++ +EG P++++RE+ +
Sbjct: 408 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTIL 466
Query: 67 HLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMM 126
+ HPN+V + ++ S D K+ +V +V+ DL + ++ + +P +P E +K +M
Sbjct: 467 KAQ---HPNIVTVREIVVGSNMD---KIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLM 519
Query: 127 FQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWY 185
QLLRG+ LH + ++HRDLK N+L++ +G +K+ DFGLAR Y + A T VVVTLWY
Sbjct: 520 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWY 579
Query: 186 RAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWP 244
RAPE+LL + Y+T VD+WSVGCIF E+ +KPLF G S++DQ+ K+ +G P E+ WP
Sbjct: 580 RAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWP 639
Query: 245 RDVALPRQAFHSKSAQPI----EKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF 300
LP + S P ++F + + G DL+ K LT+ P +RISA L H YF
Sbjct: 640 GYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 699
Query: 301 QD 302
++
Sbjct: 700 RE 701
>gi|16332370 cell division cycle 2-like 1 (PITSLRE proteins) isoform
8 [Homo sapiens]
Length = 780
Score = 229 bits (583), Expect = 3e-60
Identities = 122/302 (40%), Positives = 192/302 (63%), Gaps = 14/302 (4%)
Query: 7 CRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLR 66
CR+ ++++C+ I EG YG V++A+D K VALKR++++ +EG P++++RE+ +
Sbjct: 417 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTIL 475
Query: 67 HLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMM 126
+ HPN+V + ++ S D K+ +V +V+ DL + ++ + +P +P E +K +M
Sbjct: 476 KAQ---HPNIVTVREIVVGSNMD---KIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLM 528
Query: 127 FQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWY 185
QLLRG+ LH + ++HRDLK N+L++ +G +K+ DFGLAR Y + A T VVVTLWY
Sbjct: 529 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWY 588
Query: 186 RAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWP 244
RAPE+LL + Y+T VD+WSVGCIF E+ +KPLF G S++DQ+ K+ +G P E+ WP
Sbjct: 589 RAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWP 648
Query: 245 RDVALPRQAFHSKSAQPI----EKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF 300
LP + S P ++F + + G DL+ K LT+ P +RISA L H YF
Sbjct: 649 GYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 708
Query: 301 QD 302
++
Sbjct: 709 RE 710
>gi|16332364 cell division cycle 2-like 1 (PITSLRE proteins) isoform
5 [Homo sapiens]
Length = 748
Score = 229 bits (583), Expect = 3e-60
Identities = 122/302 (40%), Positives = 192/302 (63%), Gaps = 14/302 (4%)
Query: 7 CRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLR 66
CR+ ++++C+ I EG YG V++A+D K VALKR++++ +EG P++++RE+ +
Sbjct: 385 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTIL 443
Query: 67 HLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMM 126
+ HPN+V + ++ S D K+ +V +V+ DL + ++ + +P +P E +K +M
Sbjct: 444 KAQ---HPNIVTVREIVVGSNMD---KIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLM 496
Query: 127 FQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWY 185
QLLRG+ LH + ++HRDLK N+L++ +G +K+ DFGLAR Y + A T VVVTLWY
Sbjct: 497 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWY 556
Query: 186 RAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWP 244
RAPE+LL + Y+T VD+WSVGCIF E+ +KPLF G S++DQ+ K+ +G P E+ WP
Sbjct: 557 RAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWP 616
Query: 245 RDVALPRQAFHSKSAQPI----EKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF 300
LP + S P ++F + + G DL+ K LT+ P +RISA L H YF
Sbjct: 617 GYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 676
Query: 301 QD 302
++
Sbjct: 677 RE 678
>gi|16332362 cell division cycle 2-like 1 (PITSLRE proteins) isoform
4 [Homo sapiens]
Length = 737
Score = 229 bits (583), Expect = 3e-60
Identities = 122/302 (40%), Positives = 192/302 (63%), Gaps = 14/302 (4%)
Query: 7 CRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLR 66
CR+ ++++C+ I EG YG V++A+D K VALKR++++ +EG P++++RE+ +
Sbjct: 374 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTIL 432
Query: 67 HLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMM 126
+ HPN+V + ++ S D K+ +V +V+ DL + ++ + +P +P E +K +M
Sbjct: 433 KAQ---HPNIVTVREIVVGSNMD---KIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLM 485
Query: 127 FQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWY 185
QLLRG+ LH + ++HRDLK N+L++ +G +K+ DFGLAR Y + A T VVVTLWY
Sbjct: 486 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWY 545
Query: 186 RAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWP 244
RAPE+LL + Y+T VD+WSVGCIF E+ +KPLF G S++DQ+ K+ +G P E+ WP
Sbjct: 546 RAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWP 605
Query: 245 RDVALPRQAFHSKSAQPI----EKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF 300
LP + S P ++F + + G DL+ K LT+ P +RISA L H YF
Sbjct: 606 GYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 665
Query: 301 QD 302
++
Sbjct: 666 RE 667
>gi|16332360 cell division cycle 2-like 1 (PITSLRE proteins) isoform
3 [Homo sapiens]
Length = 526
Score = 229 bits (583), Expect = 3e-60
Identities = 122/302 (40%), Positives = 192/302 (63%), Gaps = 14/302 (4%)
Query: 7 CRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLR 66
CR+ ++++C+ I EG YG V++A+D K VALKR++++ +EG P++++RE+ +
Sbjct: 163 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTIL 221
Query: 67 HLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMM 126
+ HPN+V + ++ S D K+ +V +V+ DL + ++ + +P +P E +K +M
Sbjct: 222 KAQ---HPNIVTVREIVVGSNMD---KIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLM 274
Query: 127 FQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWY 185
QLLRG+ LH + ++HRDLK N+L++ +G +K+ DFGLAR Y + A T VVVTLWY
Sbjct: 275 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWY 334
Query: 186 RAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWP 244
RAPE+LL + Y+T VD+WSVGCIF E+ +KPLF G S++DQ+ K+ +G P E+ WP
Sbjct: 335 RAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWP 394
Query: 245 RDVALPRQAFHSKSAQPI----EKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF 300
LP + S P ++F + + G DL+ K LT+ P +RISA L H YF
Sbjct: 395 GYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 454
Query: 301 QD 302
++
Sbjct: 455 RE 456
>gi|16332358 cell division cycle 2-like 1 (PITSLRE proteins) isoform
2 [Homo sapiens]
Length = 782
Score = 229 bits (583), Expect = 3e-60
Identities = 122/302 (40%), Positives = 192/302 (63%), Gaps = 14/302 (4%)
Query: 7 CRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLR 66
CR+ ++++C+ I EG YG V++A+D K VALKR++++ +EG P++++RE+ +
Sbjct: 419 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTIL 477
Query: 67 HLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMM 126
+ HPN+V + ++ S D K+ +V +V+ DL + ++ + +P +P E +K +M
Sbjct: 478 KAQ---HPNIVTVREIVVGSNMD---KIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLM 530
Query: 127 FQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWY 185
QLLRG+ LH + ++HRDLK N+L++ +G +K+ DFGLAR Y + A T VVVTLWY
Sbjct: 531 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTLWY 590
Query: 186 RAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWP 244
RAPE+LL + Y+T VD+WSVGCIF E+ +KPLF G S++DQ+ K+ +G P E+ WP
Sbjct: 591 RAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGKSEIDQINKVFKDLGTPSEKIWP 650
Query: 245 RDVALPRQAFHSKSAQPI----EKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF 300
LP + S P ++F + + G DL+ K LT+ P +RISA L H YF
Sbjct: 651 GYSELPAVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 710
Query: 301 QD 302
++
Sbjct: 711 RE 712
>gi|148763345 cell division cycle 2-like 2 isoform 4 [Homo sapiens]
Length = 770
Score = 226 bits (577), Expect = 2e-59
Identities = 121/302 (40%), Positives = 192/302 (63%), Gaps = 14/302 (4%)
Query: 7 CRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLR 66
CR+ ++++C+ I EG YG V++A+D K VALKR++++ +EG P++++RE+ +
Sbjct: 407 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTIL 465
Query: 67 HLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMM 126
+ HPN+V + ++ S D K+ +V +V+ DL + ++ + +P +P E +K +M
Sbjct: 466 KAQ---HPNIVTVREIVVGSNMD---KIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLM 518
Query: 127 FQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWY 185
QLLRG+ LH + ++HRDLK N+L++ +G +K+ DFGLAR Y + A T VVVT WY
Sbjct: 519 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWY 578
Query: 186 RAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWP 244
RAPE+LL + Y+T VD+WSVGCIF E+ +KPLF G+S++DQ+ K+ +G P E+ WP
Sbjct: 579 RAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWP 638
Query: 245 RDVALPRQAFHSKSAQPI----EKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF 300
LP + S P ++F + + G DL+ K LT+ P +RISA L H YF
Sbjct: 639 GYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 698
Query: 301 QD 302
++
Sbjct: 699 RE 700
>gi|148763347 cell division cycle 2-like 2 isoform 1 [Homo sapiens]
Length = 780
Score = 226 bits (577), Expect = 2e-59
Identities = 121/302 (40%), Positives = 192/302 (63%), Gaps = 14/302 (4%)
Query: 7 CRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLR 66
CR+ ++++C+ I EG YG V++A+D K VALKR++++ +EG P++++RE+ +
Sbjct: 417 CRSVEEFQCLNRIEEGTYGVVYRAKDKKTD-EIVALKRLKMEKEKEGFPITSLREINTIL 475
Query: 67 HLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMM 126
+ HPN+V + ++ S D K+ +V +V+ DL + ++ + +P +P E +K +M
Sbjct: 476 KAQ---HPNIVTVREIVVGSNMD---KIYIVMNYVEHDLKSLMETMKQPFLPGE-VKTLM 528
Query: 127 FQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTLWY 185
QLLRG+ LH + ++HRDLK N+L++ +G +K+ DFGLAR Y + A T VVVT WY
Sbjct: 529 IQLLRGVKHLHDNWILHRDLKTSNLLLSHAGILKVGDFGLAREYGSPLKAYTPVVVTQWY 588
Query: 186 RAPEVLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWP 244
RAPE+LL + Y+T VD+WSVGCIF E+ +KPLF G+S++DQ+ K+ +G P E+ WP
Sbjct: 589 RAPELLLGAKEYSTAVDMWSVGCIFGELLTQKPLFPGNSEIDQINKVFKELGTPSEKIWP 648
Query: 245 RDVALPRQAFHSKSAQPI----EKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF 300
LP + S P ++F + + G DL+ K LT+ P +RISA L H YF
Sbjct: 649 GYSELPVVKKMTFSEHPYNNLRKRFGALLSDQGFDLMNKFLTYFPGRRISAEDGLKHEYF 708
Query: 301 QD 302
++
Sbjct: 709 RE 710
>gi|6912584 PFTAIRE protein kinase 1 [Homo sapiens]
Length = 451
Score = 218 bits (555), Expect = 6e-57
Identities = 130/300 (43%), Positives = 186/300 (62%), Gaps = 21/300 (7%)
Query: 13 YECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETFE 72
YE + ++GEG+Y V+K + NG + VALK +R+Q EEG P + IRE ++L+ L+
Sbjct: 117 YEKLEKLGEGSYATVYKGKSKVNG-KLVALKVIRLQE-EEGTPFTAIREASLLKGLK--- 171
Query: 73 HPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLRG 132
H N+V L D+ T LTLVFE+V DL Y+DK P G+ + +K +FQLLRG
Sbjct: 172 HANIVLLHDIIHTKET-----LTLVFEYVHTDLCQYMDKHPG-GLHPDNVKLFLFQLLRG 225
Query: 133 LDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSF-QMALTSVVVTLWYRAPEVL 191
L ++H ++HRDLKPQN+L++ +G++KLADFGLAR S ++ VVTLWYR P+VL
Sbjct: 226 LSYIHQRYILHRDLKPQNLLISDTGELKLADFGLARAKSVPSHTYSNEVVTLWYRPPDVL 285
Query: 192 LQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDV-DQLGKILDVIGLPGEEDWPRDVAL 249
L S+ Y+T +D+W VGCIF EM + F G D+ DQL +I V+G P E+ WP +L
Sbjct: 286 LGSTEYSTCLDMWGVGCIFVEMIQGVAAFPGMKDIQDQLERIFLVLGTPNEDTWPGVHSL 345
Query: 250 PR------QAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDL 303
P + SK+ + ++ ++ +DL K L +P R+SA +ALSH YF DL
Sbjct: 346 PHFKPERFTLYSSKNLRQAWNKLSYVNH-AEDLASKLLQCSPKNRLSAQAALSHEYFSDL 404
>gi|47078233 PCTAIRE protein kinase 3 isoform a [Homo sapiens]
Length = 504
Score = 211 bits (537), Expect = 7e-55
Identities = 130/298 (43%), Positives = 177/298 (59%), Gaps = 16/298 (5%)
Query: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
+ Y + ++GEG Y VFK R K VALK +R++ EEG P + IREV++L++L+
Sbjct: 172 ETYVKLDKLGEGTYATVFKGRS-KLTENLVALKEIRLEH-EEGAPCTAIREVSLLKNLK- 228
Query: 71 FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLL 130
H N+V L D+ TDR LTLVFE++D DL YLD + +K MFQLL
Sbjct: 229 --HANIVTLHDLI---HTDRS--LTLVFEYLDSDLKQYLDHCGNL-MSMHNVKIFMFQLL 280
Query: 131 RGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSF-QMALTSVVVTLWYRAPE 189
RGL + H +++HRDLKPQN+L+ G++KLADFGLAR S ++ VVTLWYR P+
Sbjct: 281 RGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPD 340
Query: 190 VLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVA 248
VLL S+ Y+TP+D+W VGCI EM +PLF GS+ ++L I ++G P EE WP A
Sbjct: 341 VLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTA 400
Query: 249 LPR---QAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDL 303
+F QP+ +D G LL L + R+SA +ALSH YF+ L
Sbjct: 401 FSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSL 458
>gi|47078231 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 211 bits (537), Expect = 7e-55
Identities = 130/298 (43%), Positives = 177/298 (59%), Gaps = 16/298 (5%)
Query: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
+ Y + ++GEG Y VFK R K VALK +R++ EEG P + IREV++L++L+
Sbjct: 142 ETYVKLDKLGEGTYATVFKGRS-KLTENLVALKEIRLEH-EEGAPCTAIREVSLLKNLK- 198
Query: 71 FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLL 130
H N+V L D+ TDR LTLVFE++D DL YLD + +K MFQLL
Sbjct: 199 --HANIVTLHDLI---HTDRS--LTLVFEYLDSDLKQYLDHCGNL-MSMHNVKIFMFQLL 250
Query: 131 RGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSF-QMALTSVVVTLWYRAPE 189
RGL + H +++HRDLKPQN+L+ G++KLADFGLAR S ++ VVTLWYR P+
Sbjct: 251 RGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPD 310
Query: 190 VLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVA 248
VLL S+ Y+TP+D+W VGCI EM +PLF GS+ ++L I ++G P EE WP A
Sbjct: 311 VLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTA 370
Query: 249 LPR---QAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDL 303
+F QP+ +D G LL L + R+SA +ALSH YF+ L
Sbjct: 371 FSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSL 428
>gi|47078229 PCTAIRE protein kinase 3 isoform b [Homo sapiens]
Length = 474
Score = 211 bits (537), Expect = 7e-55
Identities = 130/298 (43%), Positives = 177/298 (59%), Gaps = 16/298 (5%)
Query: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
+ Y + ++GEG Y VFK R K VALK +R++ EEG P + IREV++L++L+
Sbjct: 142 ETYVKLDKLGEGTYATVFKGRS-KLTENLVALKEIRLEH-EEGAPCTAIREVSLLKNLK- 198
Query: 71 FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLL 130
H N+V L D+ TDR LTLVFE++D DL YLD + +K MFQLL
Sbjct: 199 --HANIVTLHDLI---HTDRS--LTLVFEYLDSDLKQYLDHCGNL-MSMHNVKIFMFQLL 250
Query: 131 RGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSF-QMALTSVVVTLWYRAPE 189
RGL + H +++HRDLKPQN+L+ G++KLADFGLAR S ++ VVTLWYR P+
Sbjct: 251 RGLAYCHHRKILHRDLKPQNLLINERGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPD 310
Query: 190 VLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVA 248
VLL S+ Y+TP+D+W VGCI EM +PLF GS+ ++L I ++G P EE WP A
Sbjct: 311 VLLGSTEYSTPIDMWGVGCIHYEMATGRPLFPGSTVKEELHLIFRLLGTPTEETWPGVTA 370
Query: 249 LPR---QAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDL 303
+F QP+ +D G LL L + R+SA +ALSH YF+ L
Sbjct: 371 FSEFRTYSFPCYLPQPLINHAPRLDTDGIHLLSSLLLYESKSRMSAEAALSHSYFRSL 428
>gi|197333744 PCTAIRE protein kinase 1 isoform 2 [Homo sapiens]
Length = 502
Score = 209 bits (533), Expect = 2e-54
Identities = 127/300 (42%), Positives = 177/300 (59%), Gaps = 20/300 (6%)
Query: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
+ Y + ++GEG Y V+K + K VALK +R++ EEG P + IREV++L+ L+
Sbjct: 169 ETYIKLDKLGEGTYATVYKGKS-KLTDNLVALKEIRLEH-EEGAPCTAIREVSLLKDLK- 225
Query: 71 FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLL 130
H N+V L D+ E LTLVFE++D+DL YLD + +K +FQLL
Sbjct: 226 --HANIVTLHDIIHT-----EKSLTLVFEYLDKDLKQYLDDCGNI-INMHNVKLFLFQLL 277
Query: 131 RGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSF-QMALTSVVVTLWYRAPE 189
RGL + H +V+HRDLKPQN+L+ G++KLADFGLAR S ++ VVTLWYR P+
Sbjct: 278 RGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPD 337
Query: 190 VLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVA 248
+LL S+ Y+T +D+W VGCIF EM +PLF GS+ +QL I ++G P EE WP
Sbjct: 338 ILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPG--I 395
Query: 249 LPRQAFHSKS-----AQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDL 303
L + F + + A+ + +D G DLL K L F RISA A+ HP+F L
Sbjct: 396 LSNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSL 455
>gi|5453860 PCTAIRE protein kinase 1 isoform 1 [Homo sapiens]
Length = 496
Score = 209 bits (533), Expect = 2e-54
Identities = 127/300 (42%), Positives = 177/300 (59%), Gaps = 20/300 (6%)
Query: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
+ Y + ++GEG Y V+K + K VALK +R++ EEG P + IREV++L+ L+
Sbjct: 163 ETYIKLDKLGEGTYATVYKGKS-KLTDNLVALKEIRLEH-EEGAPCTAIREVSLLKDLK- 219
Query: 71 FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLL 130
H N+V L D+ E LTLVFE++D+DL YLD + +K +FQLL
Sbjct: 220 --HANIVTLHDIIHT-----EKSLTLVFEYLDKDLKQYLDDCGNI-INMHNVKLFLFQLL 271
Query: 131 RGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSF-QMALTSVVVTLWYRAPE 189
RGL + H +V+HRDLKPQN+L+ G++KLADFGLAR S ++ VVTLWYR P+
Sbjct: 272 RGLAYCHRQKVLHRDLKPQNLLINERGELKLADFGLARAKSIPTKTYSNEVVTLWYRPPD 331
Query: 190 VLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVA 248
+LL S+ Y+T +D+W VGCIF EM +PLF GS+ +QL I ++G P EE WP
Sbjct: 332 ILLGSTDYSTQIDMWGVGCIFYEMATGRPLFPGSTVEEQLHFIFRILGTPTEETWPG--I 389
Query: 249 LPRQAFHSKS-----AQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDL 303
L + F + + A+ + +D G DLL K L F RISA A+ HP+F L
Sbjct: 390 LSNEEFKTYNYPKYRAEALLSHAPRLDSDGADLLTKLLQFEGRNRISAEDAMKHPFFLSL 449
>gi|37595545 PCTAIRE protein kinase 2 [Homo sapiens]
Length = 523
Score = 209 bits (533), Expect = 2e-54
Identities = 124/298 (41%), Positives = 177/298 (59%), Gaps = 16/298 (5%)
Query: 11 QQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLET 70
+ Y + ++GEG Y V+K R K VALK +R++ EEG P + IREV++L+ L+
Sbjct: 190 ETYIKLEKLGEGTYATVYKGRS-KLTENLVALKEIRLEH-EEGAPCTAIREVSLLKDLK- 246
Query: 71 FEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLL 130
H N+V L D+ TD+ LTLVFE++D+DL Y+D + +K ++Q+L
Sbjct: 247 --HANIVTLHDIV---HTDKS--LTLVFEYLDKDLKQYMDDCGNI-MSMHNVKLFLYQIL 298
Query: 131 RGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSF-QMALTSVVVTLWYRAPE 189
RGL + H +V+HRDLKPQN+L+ G++KLADFGLAR S ++ VVTLWYR P+
Sbjct: 299 RGLAYCHRRKVLHRDLKPQNLLINEKGELKLADFGLARAKSVPTKTYSNEVVTLWYRPPD 358
Query: 190 VLLQSS-YATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWP---R 245
VLL SS Y+T +D+W VGCIF EM +PLF GS+ D+L I ++G P +E WP
Sbjct: 359 VLLGSSEYSTQIDMWGVGCIFFEMASGRPLFPGSTVEDELHLIFRLLGTPSQETWPGISS 418
Query: 246 DVALPRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYFQDL 303
+ F QP+ +D G +L+ K L + KR+SA A+ H YF+ L
Sbjct: 419 NEEFKNYNFPKYKPQPLINHAPRLDSEGIELITKFLQYESKKRVSAEEAMKHVYFRSL 476
>gi|148596926 cyclin-dependent kinase 10 isoform a [Homo sapiens]
Length = 360
Score = 207 bits (526), Expect = 1e-53
Identities = 120/321 (37%), Positives = 186/321 (57%), Gaps = 14/321 (4%)
Query: 5 GLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAV 64
G CR+ +++E + IGEG YG V++ARD + VALK+VR+ ++G+P+S++RE+ +
Sbjct: 31 GRCRSVKEFEKLNRIGEGTYGIVYRARDTQTD-EIVALKKVRMDKEKDGIPISSLREITL 89
Query: 65 LRHLETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKD 124
L L HPN+V L +V + + + LV + +QDL + L+ +P P + +K
Sbjct: 90 LLRLR---HPNIVELKEVVVGNHLE---SIFLVMGYCEQDLASLLENMPTPFSEAQ-VKC 142
Query: 125 MMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQM-ALTSVVVTL 183
++ Q+LRGL +LH + ++HRDLK N+L+T G +K ADFGLAR Y + +T VVTL
Sbjct: 143 IVLQVLRGLQYLHRNFIIHRDLKVSNLLMTDKGCVKTADFGLARAYGVPVKPMTPKVVTL 202
Query: 184 WYRAPEVLL-QSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEED 242
WYRAPE+LL ++ T +D+W+VGCI AE+ +PL G+S++ Q+ I+ ++G P E
Sbjct: 203 WYRAPELLLGTTTQTTSIDMWAVGCILAELLAHRPLLPGTSEIHQIDLIVQLLGTPSENI 262
Query: 243 WPRDVALPRQAFHSKSAQPIEKFVTD---IDELGKDLLLKCLTFNPAKRISAYSALSHPY 299
WP LP +S QP + E G LL ++P KR +A L Y
Sbjct: 263 WPGFSKLPLVGQYSLRKQPYNNLKHKFPWLSEAGLRLLHFLFMYDPKKRATAGDCLESSY 322
Query: 300 FQDLE-RCKENLDSHLPPSQN 319
F++ C+ L P +N
Sbjct: 323 FKEKPLPCEPELMPTFPHHRN 343
>gi|21040235 PFTAIRE protein kinase 2 [Homo sapiens]
Length = 384
Score = 195 bits (495), Expect = 5e-50
Identities = 121/303 (39%), Positives = 177/303 (58%), Gaps = 19/303 (6%)
Query: 9 ADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHL 68
A Y + ++GEG+Y V+K NG + VALK + + EEG+P + IRE ++L+ L
Sbjct: 48 AASSYLNLEKLGEGSYATVYKGISRING-QLVALKVISMNA-EEGVPFTAIREASLLKGL 105
Query: 69 ETFEHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQ 128
+ H N+V L D+ T LT VFE++ DL Y+ + P G+ ++ MFQ
Sbjct: 106 K---HANIVLLHDIIHTKET-----LTFVFEYMHTDLAQYMSQHPG-GLHPHNVRLFMFQ 156
Query: 129 LLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSF-QMALTSVVVTLWYRA 187
LLRGL ++H V+HRDLKPQN+L++ G++KLADFGLAR S +S VVTLWYR
Sbjct: 157 LLRGLAYIHHQHVLHRDLKPQNLLISHLGELKLADFGLARAKSIPSQTYSSEVVTLWYRP 216
Query: 188 PEVLL-QSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDV-DQLGKILDVIGLPGEEDWPR 245
P+ LL + Y++ +D+W GCIF EMF+ +PLF G S++ +QL KI +V+G+P E+ WP
Sbjct: 217 PDALLGATEYSSELDIWGAGCIFIEMFQGQPLFPGVSNILEQLEKIWEVLGVPTEDTWPG 276
Query: 246 DVALPR---QAFHSKSAQPIEKFVTDIDEL--GKDLLLKCLTFNPAKRISAYSALSHPYF 300
LP + F + + + + + +DL + L P R+SA AL H YF
Sbjct: 277 VSKLPNYNPEWFPLPTPRSLHVVWNRLGRVPEAEDLASQMLKGFPRDRVSAQEALVHDYF 336
Query: 301 QDL 303
L
Sbjct: 337 SAL 339
>gi|157817073 Cdc2-related kinase, arginine/serine-rich isoform 2
[Homo sapiens]
Length = 1481
Score = 194 bits (493), Expect = 9e-50
Identities = 126/340 (37%), Positives = 191/340 (56%), Gaps = 31/340 (9%)
Query: 2 EKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIRE 61
E D R +++ + IGEG YG+V+KA+D K+ G VALK+VR+ +EG P++ IRE
Sbjct: 716 ESDWGKRCVDKFDIIGIIGEGTYGQVYKAKD-KDTGELVALKKVRLDNEKEGFPITAIRE 774
Query: 62 VAVLRHLETFEHPNVVRLFDVCTVSRTDRETK-----LTLVFEHVDQDLTTYLDKVPEPG 116
+ +LR L H +VV + ++ T + + K LVFE++D DL L E G
Sbjct: 775 IKILRQLI---HRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLL----ESG 827
Query: 117 V---PTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQ 173
+ + IK M QL+ GL++ H +HRD+K NIL+ +SGQIKLADFGLAR+Y+ +
Sbjct: 828 LVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSE 887
Query: 174 MA--LTSVVVTLWYRAPEVLL-QSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGK 230
+ T+ V+TLWYR PE+LL + Y +D+WS GCI E+F +KP+F+ + ++ QL
Sbjct: 888 ESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLEL 947
Query: 231 ILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKF-------VTDIDELGKDLLLKCLTF 283
I + G P WP + LP + + +P +++ + I DLL LT
Sbjct: 948 ISRLCGSPCPAVWPDVIKLP----YFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTL 1003
Query: 284 NPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSEL 323
+P+KR +A L + +D+E K LP Q+ EL
Sbjct: 1004 DPSKRCTAEQTLQSDFLKDVELSK-MAPPDLPHWQDCHEL 1042
>gi|157817023 Cdc2-related kinase, arginine/serine-rich isoform 1
[Homo sapiens]
Length = 1490
Score = 194 bits (493), Expect = 9e-50
Identities = 126/340 (37%), Positives = 191/340 (56%), Gaps = 31/340 (9%)
Query: 2 EKDGLCRADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIRE 61
E D R +++ + IGEG YG+V+KA+D K+ G VALK+VR+ +EG P++ IRE
Sbjct: 716 ESDWGKRCVDKFDIIGIIGEGTYGQVYKAKD-KDTGELVALKKVRLDNEKEGFPITAIRE 774
Query: 62 VAVLRHLETFEHPNVVRLFDVCTVSRTDRETK-----LTLVFEHVDQDLTTYLDKVPEPG 116
+ +LR L H +VV + ++ T + + K LVFE++D DL L E G
Sbjct: 775 IKILRQLI---HRSVVNMKEIVTDKQDALDFKKDKGAFYLVFEYMDHDLMGLL----ESG 827
Query: 117 V---PTETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQ 173
+ + IK M QL+ GL++ H +HRD+K NIL+ +SGQIKLADFGLAR+Y+ +
Sbjct: 828 LVHFSEDHIKSFMKQLMEGLEYCHKKNFLHRDIKCSNILLNNSGQIKLADFGLARLYNSE 887
Query: 174 MA--LTSVVVTLWYRAPEVLL-QSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGK 230
+ T+ V+TLWYR PE+LL + Y +D+WS GCI E+F +KP+F+ + ++ QL
Sbjct: 888 ESRPYTNKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANLELAQLEL 947
Query: 231 ILDVIGLPGEEDWPRDVALPRQAFHSKSAQPIEKF-------VTDIDELGKDLLLKCLTF 283
I + G P WP + LP + + +P +++ + I DLL LT
Sbjct: 948 ISRLCGSPCPAVWPDVIKLP----YFNTMKPKKQYRRRLREEFSFIPSAALDLLDHMLTL 1003
Query: 284 NPAKRISAYSALSHPYFQDLERCKENLDSHLPPSQNTSEL 323
+P+KR +A L + +D+E K LP Q+ EL
Sbjct: 1004 DPSKRCTAEQTLQSDFLKDVELSK-MAPPDLPHWQDCHEL 1042
>gi|145309302 cell division cycle 2-like 5 isoform 1 [Homo sapiens]
Length = 1512
Score = 192 bits (489), Expect = 3e-49
Identities = 121/318 (38%), Positives = 179/318 (56%), Gaps = 30/318 (9%)
Query: 8 RADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRH 67
R +++ + IGEG YG+V+KARD K+ G VALK+VR+ +EG P++ IRE+ +LR
Sbjct: 700 RCVDKFDIIGIIGEGTYGQVYKARD-KDTGEMVALKKVRLDNEKEGFPITAIREIKILRQ 758
Query: 68 LETFEHPNVVRLFDVCTVSRTDRETK-----LTLVFEHVDQDLTTYLDKVPEPGVP---T 119
L H +++ + ++ T + K LVFE++D DL L E G+
Sbjct: 759 LT---HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLL----ESGLVHFNE 811
Query: 120 ETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMA--LT 177
IK M QL+ GLD+ H +HRD+K NIL+ + GQIKLADFGLAR+YS + + T
Sbjct: 812 NHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYT 871
Query: 178 SVVVTLWYRAPEVLL-QSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIG 236
+ V+TLWYR PE+LL + Y +D+WS GCI E+F +KP+F+ + ++ QL I + G
Sbjct: 872 NKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICG 931
Query: 237 LPGEEDWPRDVAL-------PRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRI 289
P WP + L P++ + K E+FV I DL L +P+KR
Sbjct: 932 SPCPAVWPDVIKLPYFNTMKPKKQYRRKLR---EEFVF-IPAAALDLFDYMLALDPSKRC 987
Query: 290 SAYSALSHPYFQDLERCK 307
+A AL + +D+E K
Sbjct: 988 TAEQALQCEFLRDVEPSK 1005
>gi|145309300 cell division cycle 2-like 5 isoform 2 [Homo sapiens]
Length = 1452
Score = 192 bits (489), Expect = 3e-49
Identities = 121/318 (38%), Positives = 179/318 (56%), Gaps = 30/318 (9%)
Query: 8 RADQQYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRH 67
R +++ + IGEG YG+V+KARD K+ G VALK+VR+ +EG P++ IRE+ +LR
Sbjct: 700 RCVDKFDIIGIIGEGTYGQVYKARD-KDTGEMVALKKVRLDNEKEGFPITAIREIKILRQ 758
Query: 68 LETFEHPNVVRLFDVCTVSRTDRETK-----LTLVFEHVDQDLTTYLDKVPEPGVP---T 119
L H +++ + ++ T + K LVFE++D DL L E G+
Sbjct: 759 LT---HQSIINMKEIVTDKEDALDFKKDKGAFYLVFEYMDHDLMGLL----ESGLVHFNE 811
Query: 120 ETIKDMMFQLLRGLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYSFQMA--LT 177
IK M QL+ GLD+ H +HRD+K NIL+ + GQIKLADFGLAR+YS + + T
Sbjct: 812 NHIKSFMRQLMEGLDYCHKKNFLHRDIKCSNILLNNRGQIKLADFGLARLYSSEESRPYT 871
Query: 178 SVVVTLWYRAPEVLL-QSSYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIG 236
+ V+TLWYR PE+LL + Y +D+WS GCI E+F +KP+F+ + ++ QL I + G
Sbjct: 872 NKVITLWYRPPELLLGEERYTPAIDVWSCGCILGELFTKKPIFQANQELAQLELISRICG 931
Query: 237 LPGEEDWPRDVAL-------PRQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRI 289
P WP + L P++ + K E+FV I DL L +P+KR
Sbjct: 932 SPCPAVWPDVIKLPYFNTMKPKKQYRRKLR---EEFVF-IPAAALDLFDYMLALDPSKRC 987
Query: 290 SAYSALSHPYFQDLERCK 307
+A AL + +D+E K
Sbjct: 988 TAEQALQCEFLRDVEPSK 1005
>gi|89903018 cell cycle related kinase isoform 3 [Homo sapiens]
Length = 346
Score = 191 bits (485), Expect = 8e-49
Identities = 114/295 (38%), Positives = 169/295 (57%), Gaps = 15/295 (5%)
Query: 12 QYECVAEIGEGAYGKVFKARDLKNGGRFVALKRVRVQTGEEGMPLSTIREVAVLRHLETF 71
QY + IGEGA+G VFKA+ ++ G VALK+V ++ E+G P +RE+ L+ +E
Sbjct: 3 QYCILGRIGEGAHGIVFKAKHVETG-EIVALKKVALRRLEDGFPNQALREIKALQEMEDN 61
Query: 72 EHPNVVRLFDVCTVSRTDRETKLTLVFEHVDQDLTTYLDKVPEPGVPTETIKDMMFQLLR 131
++ VV+L V L FE + DL + P + +K + LL+
Sbjct: 62 QY--VVQLKAVFP-----HGGGFVLAFEFMLSDLAEVVRHAQRPLAQAQ-VKSYLQMLLK 113
Query: 132 GLDFLHSHRVVHRDLKPQNILVTSSGQIKLADFGLARIYS--FQMALTSVVVTLWYRAPE 189
G+ F H++ +VHRDLKP N+L+++SGQ+K+ADFGLAR++S T V T WYRAPE
Sbjct: 114 GVAFCHANNIVHRDLKPANLLISASGQLKIADFGLARVFSPDGSRLYTHQVATRWYRAPE 173
Query: 190 VLLQS-SYATPVDLWSVGCIFAEMFRRKPLFRGSSDVDQLGKILDVIGLPGEEDWPRDVA 248
+L + Y VDLWSVGCI E+ PLF G +D++QL +L ++G P + WP
Sbjct: 174 LLYGARQYDQGVDLWSVGCIMGELLNGSPLFPGKNDIEQLCYVLRILGTPNPQVWPELTE 233
Query: 249 LP---RQAFHSKSAQPIEKFVTDIDELGKDLLLKCLTFNPAKRISAYSALSHPYF 300
LP + +F + P+E+ + D+ DLL + L + P +RI+A AL H YF
Sbjct: 234 LPDYNKISFKEQVPMPLEEVLPDVSPQALDLLGQFLLYPPHQRIAASKALLHQYF 288
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.321 0.137 0.409
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,304,619
Number of Sequences: 37866
Number of extensions: 526662
Number of successful extensions: 3318
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 752
Number of HSP's successfully gapped in prelim test: 52
Number of HSP's that attempted gapping in prelim test: 1004
Number of HSP's gapped (non-prelim): 1003
length of query: 326
length of database: 18,247,518
effective HSP length: 103
effective length of query: 223
effective length of database: 14,347,320
effective search space: 3199452360
effective search space used: 3199452360
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.