Search of human proteins with 223556008

Search of human proteins with 223556008

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|223556008 protein arginine methyltransferase 3 isoform 2
[Homo sapiens]
         (469 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|223556008 protein arginine methyltransferase 3 isoform 2 [Hom...   943   0.0  
gi|223556010 protein arginine methyltransferase 3 isoform 3 [Hom...   869   0.0  
gi|44771198 protein arginine methyltransferase 3 isoform 1 [Homo...   869   0.0  
gi|151301219 HMT1 hnRNP methyltransferase-like 2 isoform 3 [Homo...   329   4e-90
gi|154759421 HMT1 hnRNP methyltransferase-like 2 isoform 1 [Homo...   328   8e-90
gi|150456457 HMT1 hnRNP methyltransferase-like 2 isoform 2 [Homo...   328   8e-90
gi|74099699 HMT1 hnRNP methyltransferase-like 4 [Homo sapiens]        315   7e-86
gi|46255049 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens]        214   1e-55
gi|46255047 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens]        214   1e-55
gi|227908867 protein arginine methyltransferase 6 [Homo sapiens]      187   2e-47
gi|40288288 coactivator-associated arginine methyltransferase 1 ...   179   5e-45
gi|40538772 protein arginine methyltransferase 10 (putative) [Ho...    72   8e-13
gi|9506615 protein arginine methyltransferase 7 [Homo sapiens]         58   2e-08
gi|13376880 THUMP domain containing 2 [Homo sapiens]                   43   7e-04
gi|209529731 hypothetical protein LOC254013 [Homo sapiens]             40   0.006
gi|209529729 hypothetical protein LOC254013 [Homo sapiens]             40   0.006
gi|28603834 hypothetical protein LOC254013 [Homo sapiens]              40   0.006
gi|88900507 protein arginine methyltransferase 5 isoform b [Homo...    38   0.017
gi|20070220 protein arginine methyltransferase 5 isoform a [Homo...    38   0.017
gi|92859575 methyltransferase like 5 [Homo sapiens]                    37   0.039
gi|15553097 hypothetical protein MGC9084 [Homo sapiens]                36   0.086
gi|20149688 TRM2 tRNA methyltransferase 2 homolog B [Homo sapiens]     35   0.19 
gi|118600965 hexaprenyldihydroxybenzoate methyltransferase [Homo...    33   0.56 
gi|47271406 bin3, bicoid-interacting 3 [Homo sapiens]                  33   0.73 
gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo s...    32   1.6  
gi|34222389 HpaII tiny fragments locus 9C [Homo sapiens]               31   2.1  
gi|51173878 HpaII tiny fragments locus 9C [Homo sapiens]               31   2.1  
gi|45827723 hypothetical protein LOC25895 isoform b [Homo sapiens]     31   2.1  
gi|58219056 methyltransferase like 10 [Homo sapiens]                   31   2.1  
gi|7705409 HemK methyltransferase family member 1 [Homo sapiens]       31   2.8  

>gi|223556008 protein arginine methyltransferase 3 isoform 2 [Homo
           sapiens]
          Length = 469

 Score =  943 bits (2437), Expect = 0.0
 Identities = 469/469 (100%), Positives = 469/469 (100%)

Query: 1   MCSLASGATGYSHLLKKHFHTVSLSISLILTAWFINMNPTVEYMNSIYNPVPWEKEEYLK 60
           MCSLASGATGYSHLLKKHFHTVSLSISLILTAWFINMNPTVEYMNSIYNPVPWEKEEYLK
Sbjct: 1   MCSLASGATGYSHLLKKHFHTVSLSISLILTAWFINMNPTVEYMNSIYNPVPWEKEEYLK 60

Query: 61  PVLEDDLLLQFDVEDLYEPVSVPFSYPNGLSENTSVVEKLKHMEARALSAEAALARARED 120
           PVLEDDLLLQFDVEDLYEPVSVPFSYPNGLSENTSVVEKLKHMEARALSAEAALARARED
Sbjct: 61  PVLEDDLLLQFDVEDLYEPVSVPFSYPNGLSENTSVVEKLKHMEARALSAEAALARARED 120

Query: 121 LQKMKQFAQDFVMHTDVRTCSSSTSVIADLQEDEDGVYFSSYGHYGIHEEMLKDKIRTES 180
           LQKMKQFAQDFVMHTDVRTCSSSTSVIADLQEDEDGVYFSSYGHYGIHEEMLKDKIRTES
Sbjct: 121 LQKMKQFAQDFVMHTDVRTCSSSTSVIADLQEDEDGVYFSSYGHYGIHEEMLKDKIRTES 180

Query: 181 YRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKL 240
           YRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKL
Sbjct: 181 YRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKL 240

Query: 241 EDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDI 300
           EDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDI
Sbjct: 241 EDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDI 300

Query: 301 CTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVIPEAVVEVLDPKTLISEPCGIKHI 360
           CTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVIPEAVVEVLDPKTLISEPCGIKHI
Sbjct: 301 CTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVIPEAVVEVLDPKTLISEPCGIKHI 360

Query: 361 DCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQ 420
           DCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQ
Sbjct: 361 DCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQ 420

Query: 421 TVFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTLTLNNSTQTYGLQ 469
           TVFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTLTLNNSTQTYGLQ
Sbjct: 421 TVFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTLTLNNSTQTYGLQ 469


>gi|223556010 protein arginine methyltransferase 3 isoform 3 [Homo
           sapiens]
          Length = 454

 Score =  869 bits (2245), Expect = 0.0
 Identities = 432/432 (100%), Positives = 432/432 (100%)

Query: 38  NPTVEYMNSIYNPVPWEKEEYLKPVLEDDLLLQFDVEDLYEPVSVPFSYPNGLSENTSVV 97
           NPTVEYMNSIYNPVPWEKEEYLKPVLEDDLLLQFDVEDLYEPVSVPFSYPNGLSENTSVV
Sbjct: 23  NPTVEYMNSIYNPVPWEKEEYLKPVLEDDLLLQFDVEDLYEPVSVPFSYPNGLSENTSVV 82

Query: 98  EKLKHMEARALSAEAALARAREDLQKMKQFAQDFVMHTDVRTCSSSTSVIADLQEDEDGV 157
           EKLKHMEARALSAEAALARAREDLQKMKQFAQDFVMHTDVRTCSSSTSVIADLQEDEDGV
Sbjct: 83  EKLKHMEARALSAEAALARAREDLQKMKQFAQDFVMHTDVRTCSSSTSVIADLQEDEDGV 142

Query: 158 YFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAK 217
           YFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAK
Sbjct: 143 YFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAK 202

Query: 218 KVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFES 277
           KVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFES
Sbjct: 203 KVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFES 262

Query: 278 MLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVI 337
           MLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVI
Sbjct: 263 MLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVI 322

Query: 338 PEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYF 397
           PEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYF
Sbjct: 323 PEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYF 382

Query: 398 EKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTL 457
           EKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTL
Sbjct: 383 EKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTL 442

Query: 458 TLNNSTQTYGLQ 469
           TLNNSTQTYGLQ
Sbjct: 443 TLNNSTQTYGLQ 454


>gi|44771198 protein arginine methyltransferase 3 isoform 1 [Homo
           sapiens]
          Length = 531

 Score =  869 bits (2245), Expect = 0.0
 Identities = 432/432 (100%), Positives = 432/432 (100%)

Query: 38  NPTVEYMNSIYNPVPWEKEEYLKPVLEDDLLLQFDVEDLYEPVSVPFSYPNGLSENTSVV 97
           NPTVEYMNSIYNPVPWEKEEYLKPVLEDDLLLQFDVEDLYEPVSVPFSYPNGLSENTSVV
Sbjct: 100 NPTVEYMNSIYNPVPWEKEEYLKPVLEDDLLLQFDVEDLYEPVSVPFSYPNGLSENTSVV 159

Query: 98  EKLKHMEARALSAEAALARAREDLQKMKQFAQDFVMHTDVRTCSSSTSVIADLQEDEDGV 157
           EKLKHMEARALSAEAALARAREDLQKMKQFAQDFVMHTDVRTCSSSTSVIADLQEDEDGV
Sbjct: 160 EKLKHMEARALSAEAALARAREDLQKMKQFAQDFVMHTDVRTCSSSTSVIADLQEDEDGV 219

Query: 158 YFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAK 217
           YFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAK
Sbjct: 220 YFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAK 279

Query: 218 KVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFES 277
           KVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFES
Sbjct: 280 KVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFES 339

Query: 278 MLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVI 337
           MLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVI
Sbjct: 340 MLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVI 399

Query: 338 PEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYF 397
           PEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYF
Sbjct: 400 PEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYF 459

Query: 398 EKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTL 457
           EKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTL
Sbjct: 460 EKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTL 519

Query: 458 TLNNSTQTYGLQ 469
           TLNNSTQTYGLQ
Sbjct: 520 TLNNSTQTYGLQ 531


>gi|151301219 HMT1 hnRNP methyltransferase-like 2 isoform 3 [Homo
           sapiens]
          Length = 353

 Score =  329 bits (843), Expect = 4e-90
 Identities = 163/333 (48%), Positives = 226/333 (67%), Gaps = 2/333 (0%)

Query: 128 AQDFVMHTDVRTCSSSTSVIADLQEDEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQ 187
           A + +M        SS    A+    +D  YF SY H+GIHEEMLKD++RT +YR+ ++ 
Sbjct: 6   AANCIMEVSCGQAESSEKPNAEDMTSKD-YYFDSYAHFGIHEEMLKDEVRTLTYRNSMFH 64

Query: 188 NPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLI 247
           N H+FKDKVVLDVG GTGIL MFAAKAGA+KV+G++ S I   A+ I++ NKL+  +T+I
Sbjct: 65  NRHLFKDKVVLDVGSGTGILCMFAAKAGARKVIGIECSSISDYAVKIVKANKLDHVVTII 124

Query: 248 KGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVA 307
           KGK+EEV LPVEKVD+IISEWMGY L +ESML++VLYA++K+LA  G ++PD  T+ + A
Sbjct: 125 KGKVEEVELPVEKVDIIISEWMGYCLFYESMLNTVLYARDKWLAPDGLIFPDRATLYVTA 184

Query: 308 VSDVNKHADRIAFWDDVYGFKMSCMKKAVIPEAVVEVLDPKTLISEPCGIKHIDCHTTSI 367
           + D      +I +W++VYGF MSC+K   I E +V+V+DPK L++  C IK +D +T  +
Sbjct: 185 IEDRQYKDYKIHWWENVYGFDMSCIKDVAIKEPLVDVVDPKQLVTNACLIKEVDIYTVKV 244

Query: 368 SDLEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLEK 427
            DL F+S F L++ R     A+  YF+I F + CH R  FST P+S  THWKQTVF +E 
Sbjct: 245 EDLTFTSPFCLQVKRNDYVHALVAYFNIEFTR-CHKRTGFSTSPESPYTHWKQTVFYMED 303

Query: 428 PFSVKAGEALKGKVTVHKNKKDPRSLTVTLTLN 460
             +VK GE + G + +  N K+ R L  T+ L+
Sbjct: 304 YLTVKTGEEIFGTIGMRPNAKNNRDLDFTIDLD 336


>gi|154759421 HMT1 hnRNP methyltransferase-like 2 isoform 1 [Homo
           sapiens]
          Length = 371

 Score =  328 bits (840), Expect = 8e-90
 Identities = 157/303 (51%), Positives = 216/303 (71%), Gaps = 1/303 (0%)

Query: 158 YFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAK 217
           YF SY H+GIHEEMLKD++RT +YR+ ++ N H+FKDKVVLDVG GTGIL MFAAKAGA+
Sbjct: 53  YFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGAR 112

Query: 218 KVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFES 277
           KV+G++ S I   A+ I++ NKL+  +T+IKGK+EEV LPVEKVD+IISEWMGY L +ES
Sbjct: 113 KVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYES 172

Query: 278 MLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVI 337
           ML++VLYA++K+LA  G ++PD  T+ + A+ D      +I +W++VYGF MSC+K   I
Sbjct: 173 MLNTVLYARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAI 232

Query: 338 PEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYF 397
            E +V+V+DPK L++  C IK +D +T  + DL F+S F L++ R     A+  YF+I F
Sbjct: 233 KEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEF 292

Query: 398 EKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTL 457
            + CH R  FST P+S  THWKQTVF +E   +VK GE + G + +  N K+ R L  T+
Sbjct: 293 TR-CHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTI 351

Query: 458 TLN 460
            L+
Sbjct: 352 DLD 354


>gi|150456457 HMT1 hnRNP methyltransferase-like 2 isoform 2 [Homo
           sapiens]
          Length = 347

 Score =  328 bits (840), Expect = 8e-90
 Identities = 157/303 (51%), Positives = 216/303 (71%), Gaps = 1/303 (0%)

Query: 158 YFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAK 217
           YF SY H+GIHEEMLKD++RT +YR+ ++ N H+FKDKVVLDVG GTGIL MFAAKAGA+
Sbjct: 29  YFDSYAHFGIHEEMLKDEVRTLTYRNSMFHNRHLFKDKVVLDVGSGTGILCMFAAKAGAR 88

Query: 218 KVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFES 277
           KV+G++ S I   A+ I++ NKL+  +T+IKGK+EEV LPVEKVD+IISEWMGY L +ES
Sbjct: 89  KVIGIECSSISDYAVKIVKANKLDHVVTIIKGKVEEVELPVEKVDIIISEWMGYCLFYES 148

Query: 278 MLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVI 337
           ML++VLYA++K+LA  G ++PD  T+ + A+ D      +I +W++VYGF MSC+K   I
Sbjct: 149 MLNTVLYARDKWLAPDGLIFPDRATLYVTAIEDRQYKDYKIHWWENVYGFDMSCIKDVAI 208

Query: 338 PEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYF 397
            E +V+V+DPK L++  C IK +D +T  + DL F+S F L++ R     A+  YF+I F
Sbjct: 209 KEPLVDVVDPKQLVTNACLIKEVDIYTVKVEDLTFTSPFCLQVKRNDYVHALVAYFNIEF 268

Query: 398 EKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTL 457
            + CH R  FST P+S  THWKQTVF +E   +VK GE + G + +  N K+ R L  T+
Sbjct: 269 TR-CHKRTGFSTSPESPYTHWKQTVFYMEDYLTVKTGEEIFGTIGMRPNAKNNRDLDFTI 327

Query: 458 TLN 460
            L+
Sbjct: 328 DLD 330


>gi|74099699 HMT1 hnRNP methyltransferase-like 4 [Homo sapiens]
          Length = 394

 Score =  315 bits (806), Expect = 7e-86
 Identities = 151/303 (49%), Positives = 214/303 (70%), Gaps = 1/303 (0%)

Query: 158 YFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAK 217
           YF SY H+GIHEEMLKD++RT +YR+ +Y N H+FKDKVVLDVG GTGILSMFAAKAGAK
Sbjct: 76  YFDSYAHFGIHEEMLKDEVRTLTYRNSMYHNKHVFKDKVVLDVGSGTGILSMFAAKAGAK 135

Query: 218 KVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFES 277
           KV G++ S I   +  II+ N L++ IT+ KGK+EEV LPVEKVD+IISEWMGY L +ES
Sbjct: 136 KVFGIECSSISDYSEKIIKANHLDNIITIFKGKVEEVELPVEKVDIIISEWMGYCLFYES 195

Query: 278 MLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKKAVI 337
           ML++V++A++K+L  GG ++PD   + +VA+ D      +I +W++VYGF M+C++   +
Sbjct: 196 MLNTVIFARDKWLKPGGLMFPDRAALYVVAIEDRQYKDFKIHWWENVYGFDMTCIRDVAM 255

Query: 338 PEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYF 397
            E +V+++DPK +++  C IK +D +T    +L F+S F L+I R     A+  YF+I F
Sbjct: 256 KEPLVDIVDPKQVVTNACLIKEVDIYTVKTEELSFTSAFCLQIQRNDYVHALVTYFNIEF 315

Query: 398 EKNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTL 457
            K CH ++ FST P +  THWKQTVF LE   +V+ GE + G +++  N K+ R L  T+
Sbjct: 316 TK-CHKKMGFSTAPDAPYTHWKQTVFYLEDYLTVRRGEEIYGTISMKPNAKNVRDLDFTV 374

Query: 458 TLN 460
            L+
Sbjct: 375 DLD 377


>gi|46255049 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens]
          Length = 433

 Score =  214 bits (546), Expect = 1e-55
 Identities = 119/319 (37%), Positives = 178/319 (55%), Gaps = 12/319 (3%)

Query: 149 DLQEDEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILS 208
           D  +DE+  YF SYG   +H EML D+ RT  Y   I QN     DKV+LDVGCGTGI+S
Sbjct: 95  DTWQDEE--YFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIIS 152

Query: 209 MFAAK-AGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISE 267
           +F A  A  + V  V+ SE+      ++  N   D IT+ + K+E+V LP EKVDV++SE
Sbjct: 153 LFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLP-EKVDVLVSE 211

Query: 268 WMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGF 327
           WMG  LLFE M++S+LYA++ +L + G ++P +  + LV  S    +  ++ FWD+ Y F
Sbjct: 212 WMGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLVPCSADKDYRSKVLFWDNAYEF 271

Query: 328 KMSCMKKAVIPEAVVE-----VLDPKTLISEPCGIKHIDCHTTSISDLE-FSSDFTLKIT 381
            +S +K   + E   +     +L P+  +SEPC I  +D  T  ISDLE    +    I 
Sbjct: 272 NLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETLRGELRFDIR 331

Query: 382 RTSMCTAIAGYFDIYFEKNCHNR--VVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKG 439
           +         +F ++F+     +   V STGP    THWKQT+F+++ P  V  G+ + G
Sbjct: 332 KAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTG 391

Query: 440 KVTVHKNKKDPRSLTVTLT 458
            V + +N    R ++V L+
Sbjct: 392 SVVLQRNPVWRRHMSVALS 410


>gi|46255047 HMT1 hnRNP methyltransferase-like 1 [Homo sapiens]
          Length = 433

 Score =  214 bits (546), Expect = 1e-55
 Identities = 119/319 (37%), Positives = 178/319 (55%), Gaps = 12/319 (3%)

Query: 149 DLQEDEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILS 208
           D  +DE+  YF SYG   +H EML D+ RT  Y   I QN     DKV+LDVGCGTGI+S
Sbjct: 95  DTWQDEE--YFGSYGTLKLHLEMLADQPRTTKYHSVILQNKESLTDKVILDVGCGTGIIS 152

Query: 209 MFAAK-AGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISE 267
           +F A  A  + V  V+ SE+      ++  N   D IT+ + K+E+V LP EKVDV++SE
Sbjct: 153 LFCAHYARPRAVYAVEASEMAQHTGQLVLQNGFADIITVYQQKVEDVVLP-EKVDVLVSE 211

Query: 268 WMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGF 327
           WMG  LLFE M++S+LYA++ +L + G ++P +  + LV  S    +  ++ FWD+ Y F
Sbjct: 212 WMGTCLLFEFMIESILYARDAWLKEDGVIWPTMAALHLVPCSADKDYRSKVLFWDNAYEF 271

Query: 328 KMSCMKKAVIPEAVVE-----VLDPKTLISEPCGIKHIDCHTTSISDLE-FSSDFTLKIT 381
            +S +K   + E   +     +L P+  +SEPC I  +D  T  ISDLE    +    I 
Sbjct: 272 NLSALKSLAVKEFFSKPKYNHILKPEDCLSEPCTILQLDMRTVQISDLETLRGELRFDIR 331

Query: 382 RTSMCTAIAGYFDIYFEKNCHNR--VVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEALKG 439
           +         +F ++F+     +   V STGP    THWKQT+F+++ P  V  G+ + G
Sbjct: 332 KAGTLHGFTAWFSVHFQSLQEGQPPQVLSTGPFHPTTHWKQTLFMMDDPVPVHTGDVVTG 391

Query: 440 KVTVHKNKKDPRSLTVTLT 458
            V + +N    R ++V L+
Sbjct: 392 SVVLQRNPVWRRHMSVALS 410


>gi|227908867 protein arginine methyltransferase 6 [Homo sapiens]
          Length = 375

 Score =  187 bits (475), Expect = 2e-47
 Identities = 113/320 (35%), Positives = 174/320 (54%), Gaps = 15/320 (4%)

Query: 151 QEDEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMF 210
           + + D +Y+  Y    +HEEM+ D++RT++YR  I +N    + K VLDVG GTGILS+F
Sbjct: 40  KRERDQLYYECYSDVSVHEEMIADRVRTDAYRLGILRNWAALRGKTVLDVGAGTGILSIF 99

Query: 211 AAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMG 270
            A+AGA++V  V+ S I  QA +++R N LED + ++ G +E V LP E+VD I+SEWMG
Sbjct: 100 CAQAGARRVYAVEASAIWQQAREVVRFNGLEDRVHVLPGPVETVELP-EQVDAIVSEWMG 158

Query: 271 YFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDV---YGF 327
           Y LL ESML SVL+A+ K+L +GG + P    + +  +SD      R+ FW  V   YG 
Sbjct: 159 YGLLHESMLSSVLHARTKWLKEGGLLLPASAELFIAPISD-QMLEWRLGFWSQVKQHYGV 217

Query: 328 KMSCMKKAVI------PEAVVEVLDPKTLISEPCGIKHIDCHTTSI-SDLE--FSSDFTL 378
            MSC++           E VV+ L  + +++ P     ++     +  +LE      F  
Sbjct: 218 DMSCLEGFATRCLMGHSEIVVQGLSGEDVLARPQRFAQLELSRAGLEQELEAGVGGRFRC 277

Query: 379 KITRTSMCTAIAGYFDIYFE-KNCHNRVVFSTGPQSTKTHWKQTVFLLEKPFSVKAGEAL 437
               ++     A +F + F        +V ST P    THWKQ +  L +P  V+    +
Sbjct: 278 SCYGSAPMHGFAIWFQVTFPGGESEKPLVLSTSPFHPATHWKQALLYLNEPVQVEQDTDV 337

Query: 438 KGKVTVHKNKKDPRSLTVTL 457
            G++T+  ++ +PR L V L
Sbjct: 338 SGEITLLPSRDNPRRLRVLL 357


>gi|40288288 coactivator-associated arginine methyltransferase 1
           [Homo sapiens]
          Length = 608

 Score =  179 bits (454), Expect = 5e-45
 Identities = 115/341 (33%), Positives = 183/341 (53%), Gaps = 20/341 (5%)

Query: 137 VRTCSSST---SVIADLQEDEDGV-YFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIF 192
           ++TC   T   SV ++  E+   V YF  YG+    + M++D +RT +Y+  I QN   F
Sbjct: 124 LKTCRGHTLERSVFSERTEESSAVQYFQFYGYLSQQQNMMQDYVRTGTYQRAILQNHTDF 183

Query: 193 KDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIE 252
           KDK+VLDVGCG+GILS FAA+AGA+K+  V+ S +   A  +++ N L D I +I GK+E
Sbjct: 184 KDKIVLDVGCGSGILSFFAAQAGARKIYAVEASTMAQHAEVLVKSNNLTDRIVVIPGKVE 243

Query: 253 EVHLPVEKVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVN 312
           EV LP E+VD+IISE MGY L  E ML+S L+AK KYL   G+++P I  + L   +D  
Sbjct: 244 EVSLP-EQVDIIISEPMGYMLFNERMLESYLHAK-KYLKPSGNMFPTIGDVHLAPFTDEQ 301

Query: 313 KHADRIA---FW--DDVYGFKMSCMKKAVIPE----AVVEVLDPKTLISEPC--GIKHID 361
            + ++     FW     +G  +S ++ A + E     VV+  D + L+++     +  ++
Sbjct: 302 LYMEQFTKANFWYQPSFHGVDLSALRGAAVDEYFRQPVVDTFDIRILMAKSVKYTVNFLE 361

Query: 362 CHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQSTKTHWKQT 421
                +  +E    F   +  + +   +A +FD+ F  +    V  ST P    THW Q 
Sbjct: 362 AKEGDLHRIEI--PFKFHMLHSGLVHGLAFWFDVAFIGSIMT-VWLSTAPTEPLTHWYQV 418

Query: 422 VFLLEKPFSVKAGEALKGKVTVHKNKKDPRSLTVTLTLNNS 462
             L + P   KAG+ L G   +  NK+    +++   ++ +
Sbjct: 419 RCLFQSPLFAKAGDTLSGTCLLIANKRQSYDISIVAQVDQT 459


>gi|40538772 protein arginine methyltransferase 10 (putative) [Homo
           sapiens]
          Length = 845

 Score = 72.4 bits (176), Expect = 8e-13
 Identities = 83/310 (26%), Positives = 137/310 (44%), Gaps = 39/310 (12%)

Query: 168 HEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEI 227
           H  ML D  R   Y   I Q       K VLD+G GTGILSMFA KAGA  V   + S+ 
Sbjct: 153 HFIMLNDTKRNTIYNAAI-QKAVCLGSKSVLDIGAGTGILSMFAKKAGAHSVYACELSKT 211

Query: 228 LYQ-AMDIIRLNKLEDTITLIKGKIEEVHLP---VEKVDVIISEWMGYFLLFESMLDSVL 283
           +Y+ A D++  NK+E  I L+  K  ++ +P    E+V ++++E +   L  E +++S++
Sbjct: 212 MYELACDVVAANKMEAGIKLLHTKSLDIEIPKHIPERVSLVVTETVDAGLFGEGIVESLI 271

Query: 284 YAKNKYL------------AKGGSVYPDICTISLVAV--SDVNKHADRIAFWDDVYGFKM 329
           +A    L             K G V P    I  +AV  +++ +H  R+    D+ G  +
Sbjct: 272 HAWEHLLLQPKTKGESANCEKYGKVIPASAVIFGMAVECAEIRRH-HRVGI-KDIAGIHL 329

Query: 330 SCMKK-------AVIPEAVVEVLDPKTLISEPCG-IKHIDCHTTSISDL----EFSSDFT 377
               K       +V  E  +E    + +   P G +   +C      D     E  S  T
Sbjct: 330 PTNVKFQSPAYSSVDTEETIEPYTTEKMSRVPGGYLALTECFEIMTVDFNNLQELKSLAT 389

Query: 378 LKITRTSMCTAIAGYFD---IYFEKNCHNRVVFSTGPQSTKTHWKQTVFLLE--KPFSVK 432
            K  +  +     G  D   ++F     +    ST P S +T W+Q V+ ++    + +K
Sbjct: 390 KKPDKIGIPVIKEGILDAIMVWFVLQLDDEHSLSTSP-SEETCWEQAVYPVQDLADYWIK 448

Query: 433 AGEALKGKVT 442
            G+ +  +V+
Sbjct: 449 PGDHVMMEVS 458



 Score = 37.7 bits (86), Expect = 0.023
 Identities = 54/274 (19%), Positives = 111/274 (40%), Gaps = 30/274 (10%)

Query: 190 HIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIR------------- 236
           +I +   VLDV  G  +L + A   G  K     + +    A+D+I              
Sbjct: 577 NILEPFYVLDVSEGFSVLPVIAGTLGQVKPYSSVEKDQHRIALDLISEANHFPKETLEFW 636

Query: 237 LNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSV 296
           L  +ED   +++    +    +  +DVI  E  G  L+ + +++    ++   L  GG +
Sbjct: 637 LRHVEDESAMLQRPKSDKLWSIIILDVI--EPSG--LIQQEIMEKAAISRC-LLQSGGKI 691

Query: 297 YPD-ICTISLVAVSDVNKHADRIAFWDDVYGFKMS-CMKKAVIPEAVVEVLD--PKTLIS 352
           +P  +    L+  S      + +   +   G  ++  + +  +P  V   L   P   +S
Sbjct: 692 FPQYVLMFGLLVESQTLLEENAVQGTERTLGLNIAPFINQFQVPIRVFLDLSSLPCIPLS 751

Query: 353 EPCGIKHIDCHTTSISDLEFSSDFTLKITRTSMCTAIAGYFDIYFEKNCHNRVVFSTGPQ 412
           +P  +  +D  T  ++    + +  + + ++   TAI  ++ +Y ++             
Sbjct: 752 KPVELLRLDLMTPYLNTS--NREVKVYVCKSGRLTAIPFWYHMYLDEEIR------LDTS 803

Query: 413 STKTHWKQTVFLLEKPFSVKAGEALKGKVTVHKN 446
           S  +HWKQ   +L+ P  V+ GE L   +  HK+
Sbjct: 804 SEASHWKQAAVVLDNPIQVEMGEELVLSIQHHKS 837


>gi|9506615 protein arginine methyltransferase 7 [Homo sapiens]
          Length = 692

 Score = 58.2 bits (139), Expect = 2e-08
 Identities = 77/339 (22%), Positives = 135/339 (39%), Gaps = 60/339 (17%)

Query: 143 STSVIADLQEDEDGVYFSSYGHYGIHEE--------MLKDKIRTESYRDFIYQNPHIFKD 194
           +T  +  L+EDE         HY  H+E        ML DK R   Y   I       KD
Sbjct: 11  TTGSVEWLEEDE---------HYDYHQEIARSSYADMLHDKDRNVKYYQGIRAAVSRVKD 61

Query: 195 K----VVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQ-AMDIIRLNKLEDTITLIKG 249
           +    +VLD+G GTG+LSM A  AGA     ++  + +   A+ I+  N   D I +I  
Sbjct: 62  RGQKALVLDIGTGTGLLSMMAVTAGADFCYAIEVFKPMADAAVKIVEKNGFSDKIKVINK 121

Query: 250 KIEEVHLPVE-----KVDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTIS 304
              EV +  E     + +++++E     L+ E  L S  +A    + +     P   T+ 
Sbjct: 122 HSTEVTVGPEGDMPCRANILVTELFDTELIGEGALPSYEHAHRHLVEENCEAVPHRATVY 181

Query: 305 LVAVSDVNKHADRIAFWDDVYGF--KMSCMKKAVIPEAVVEVLDPKTLISEPCGIKHIDC 362
              V      + R+  W+ ++    + S  ++ ++P   VE       + +    +    
Sbjct: 182 AQLV-----ESGRMWSWNKLFPIHVQTSLGEQVIVPPVDVESCPGAPSVCDIQLNQVSPA 236

Query: 363 HTTSISDL--EFSSDFTLKITRTSMC-------------TAIAGYFDIYFEKNCHNRVVF 407
             T +SD+   FS DF+ +++ ++ C               +  ++DI  E +   ++  
Sbjct: 237 DFTVLSDVLPMFSIDFSKQVSSSAACHSRRFEPLTSGRAQVVLSWWDI--EMDPEGKIKC 294

Query: 408 STGP---------QSTKTHWKQTVFLLEKPFSVKAGEAL 437
           +  P            + HW Q V+ L +   V  G AL
Sbjct: 295 TMAPFWAHSDPEEMQWRDHWMQCVYFLPQEEPVVQGSAL 333


>gi|13376880 THUMP domain containing 2 [Homo sapiens]
          Length = 473

 Score = 42.7 bits (99), Expect = 7e-04
 Identities = 35/103 (33%), Positives = 51/103 (49%), Gaps = 3/103 (2%)

Query: 197 VLDVGCGTGILSMFAAKAGAKKV-LGVDQSEI-LYQAMDIIRLNKLEDTITLIKGKIEEV 254
           VLD  CG G + + AAK       +G D S+  L    D ++   LED I L+K  + E+
Sbjct: 272 VLDPMCGLGTILLEAAKEWPDVYYVGADVSDSQLLGTWDNLKAAGLEDKIELLKISVIEL 331

Query: 255 HLPVEKVDVIISEW-MGYFLLFESMLDSVLYAKNKYLAKGGSV 296
            LP E VD+IIS+   G        + S+L    + L  GG++
Sbjct: 332 PLPSESVDIIISDIPFGKKFKLGKDIKSILQEMERVLHVGGTI 374


>gi|209529731 hypothetical protein LOC254013 [Homo sapiens]
          Length = 262

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 28/100 (28%), Positives = 51/100 (51%), Gaps = 7/100 (7%)

Query: 184 FIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDI-IRLNKLED 242
           ++  NP + + K VLD+G G G  ++ A  +GA ++L  D   I   A+ +   LN+L  
Sbjct: 106 YLLDNPDVVRGKSVLDLGSGCGATAIAAKMSGASRILANDIDPIAGMAITLNCELNRLNP 165

Query: 243 TITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSV 282
              LI+  +   +L  +K D+++   +G     E + DS+
Sbjct: 166 FPILIQNIL---NLEQDKWDLVV---LGDMFYDEDLADSL 199


>gi|209529729 hypothetical protein LOC254013 [Homo sapiens]
          Length = 262

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 28/100 (28%), Positives = 51/100 (51%), Gaps = 7/100 (7%)

Query: 184 FIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDI-IRLNKLED 242
           ++  NP + + K VLD+G G G  ++ A  +GA ++L  D   I   A+ +   LN+L  
Sbjct: 106 YLLDNPDVVRGKSVLDLGSGCGATAIAAKMSGASRILANDIDPIAGMAITLNCELNRLNP 165

Query: 243 TITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSV 282
              LI+  +   +L  +K D+++   +G     E + DS+
Sbjct: 166 FPILIQNIL---NLEQDKWDLVV---LGDMFYDEDLADSL 199


>gi|28603834 hypothetical protein LOC254013 [Homo sapiens]
          Length = 262

 Score = 39.7 bits (91), Expect = 0.006
 Identities = 28/100 (28%), Positives = 51/100 (51%), Gaps = 7/100 (7%)

Query: 184 FIYQNPHIFKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDI-IRLNKLED 242
           ++  NP + + K VLD+G G G  ++ A  +GA ++L  D   I   A+ +   LN+L  
Sbjct: 106 YLLDNPDVVRGKSVLDLGSGCGATAIAAKMSGASRILANDIDPIAGMAITLNCELNRLNP 165

Query: 243 TITLIKGKIEEVHLPVEKVDVIISEWMGYFLLFESMLDSV 282
              LI+  +   +L  +K D+++   +G     E + DS+
Sbjct: 166 FPILIQNIL---NLEQDKWDLVV---LGDMFYDEDLADSL 199


>gi|88900507 protein arginine methyltransferase 5 isoform b [Homo
           sapiens]
          Length = 620

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 65/297 (21%), Positives = 115/297 (38%), Gaps = 49/297 (16%)

Query: 168 HEEMLKDKIRTESYRDFIYQN-----PHIFKD---KVVLDVGCGTGIL---SMFAAKAGA 216
           +E   KD I+   Y+  IY+      P   KD   +V++ +G G G L   S+ AAK   
Sbjct: 307 YEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQAD 366

Query: 217 K--KVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLL 274
           +  K+  V+++      ++  +  +    +T++   + E   P EK D+I+SE +G F  
Sbjct: 367 RRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAP-EKADIIVSELLGSFAD 425

Query: 275 FESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKK 334
            E +    L     +L   G   P   T  L  +S              +Y    +C +K
Sbjct: 426 NE-LSPECLDGAQHFLKDDGVSIPGEYTSFLAPISS-----------SKLYNEVRACREK 473

Query: 335 AVIPEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLK---ITRTSMCT---- 387
              PEA  E+         P  ++  + H  S     F+     +   I     CT    
Sbjct: 474 DRDPEAQFEM---------PYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFP 524

Query: 388 ----AIAGYFDIYFEKNCHNRVVFSTGPQSTKT---HWKQTVFLLEKPFSVKAGEAL 437
                +   F  YFE   +  +  S  P++       W   +F +++P +V+ G+ +
Sbjct: 525 VEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTI 581


>gi|20070220 protein arginine methyltransferase 5 isoform a [Homo
           sapiens]
          Length = 637

 Score = 38.1 bits (87), Expect = 0.017
 Identities = 65/297 (21%), Positives = 115/297 (38%), Gaps = 49/297 (16%)

Query: 168 HEEMLKDKIRTESYRDFIYQN-----PHIFKD---KVVLDVGCGTGIL---SMFAAKAGA 216
           +E   KD I+   Y+  IY+      P   KD   +V++ +G G G L   S+ AAK   
Sbjct: 324 YEVFEKDPIKYSQYQQAIYKCLLDRVPEEEKDTNVQVLMVLGAGRGPLVNASLRAAKQAD 383

Query: 217 K--KVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVDVIISEWMGYFLL 274
           +  K+  V+++      ++  +  +    +T++   + E   P EK D+I+SE +G F  
Sbjct: 384 RRIKLYAVEKNPNAVVTLENWQFEEWGSQVTVVSSDMREWVAP-EKADIIVSELLGSFAD 442

Query: 275 FESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVYGFKMSCMKK 334
            E +    L     +L   G   P   T  L  +S              +Y    +C +K
Sbjct: 443 NE-LSPECLDGAQHFLKDDGVSIPGEYTSFLAPISS-----------SKLYNEVRACREK 490

Query: 335 AVIPEAVVEVLDPKTLISEPCGIKHIDCHTTSISDLEFSSDFTLK---ITRTSMCT---- 387
              PEA  E+         P  ++  + H  S     F+     +   I     CT    
Sbjct: 491 DRDPEAQFEM---------PYVVRLHNFHQLSAPQPCFTFSHPNRDPMIDNNRYCTLEFP 541

Query: 388 ----AIAGYFDIYFEKNCHNRVVFSTGPQSTKT---HWKQTVFLLEKPFSVKAGEAL 437
                +   F  YFE   +  +  S  P++       W   +F +++P +V+ G+ +
Sbjct: 542 VEVNTVLHGFAGYFETVLYQDITLSIRPETHSPGMFSWFPILFPIKQPITVREGQTI 598


>gi|92859575 methyltransferase like 5 [Homo sapiens]
          Length = 209

 Score = 37.0 bits (84), Expect = 0.039
 Identities = 22/55 (40%), Positives = 31/55 (56%), Gaps = 3/55 (5%)

Query: 193 KDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLI 247
           ++KVV D+GCG G+LS+  A  GA   +G D  E    A++I   N  E  +T I
Sbjct: 51  ENKVVADLGCGCGVLSIGTAMLGAGLCVGFDIDE---DALEIFNRNAEEFELTNI 102


>gi|15553097 hypothetical protein MGC9084 [Homo sapiens]
          Length = 372

 Score = 35.8 bits (81), Expect = 0.086
 Identities = 18/54 (33%), Positives = 33/54 (61%), Gaps = 3/54 (5%)

Query: 192 FKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAM---DIIRLNKLED 242
           F  K VLD+GCG+G+L + A K G+K++   D + ++   +   +++  + LED
Sbjct: 186 FAGKKVLDLGCGSGLLGITAFKGGSKEIHFQDYNSMVIDEVTLPNVVANSTLED 239


>gi|20149688 TRM2 tRNA methyltransferase 2 homolog B [Homo sapiens]
          Length = 504

 Score = 34.7 bits (78), Expect = 0.19
 Identities = 33/146 (22%), Positives = 64/146 (43%), Gaps = 21/146 (14%)

Query: 117 AREDLQKMKQFAQDFVMHTDVRTCSSSTSVIADLQ----EDEDGVYFSSYGHYGIHEEML 172
           ++E+L   K+  ++F +      C  ++    +        +   Y   +G   I EE+L
Sbjct: 251 SQEELHVQKEIVKEFFIRGPGAACGLTSLYFQESTMTRCSHQQSPYQLLFGEPYIFEELL 310

Query: 173 KDKIRTE---------SYRDFIYQN----PHIFKDKVVLDVGCGTGILSMFAAKAGAKKV 219
             KIR           +  + +Y+       +  D ++LD+ CGTG++ +  A+    +V
Sbjct: 311 SLKIRISPDAFFQINTAGAEMLYRTVGELTGVNSDTILLDICCGTGVIGLSLAQ-HTSRV 369

Query: 220 LGVDQSEILYQAMDIIRLNKLEDTIT 245
           LG+   E+L QA++  R     + IT
Sbjct: 370 LGI---ELLEQAVEDARWTAAFNGIT 392


>gi|118600965 hexaprenyldihydroxybenzoate methyltransferase [Homo
           sapiens]
          Length = 369

 Score = 33.1 bits (74), Expect = 0.56
 Identities = 48/208 (23%), Positives = 89/208 (42%), Gaps = 27/208 (12%)

Query: 153 DEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGILSMFAA 212
           DE GVY   +    +    ++D +         +Q         +LDVGCG G+L+    
Sbjct: 109 DEQGVYAPLHSMNDLRVPFIRDNLLKTIPN---HQPGKPLLGMKILDVGCGGGLLTEPLG 165

Query: 213 KAGAKKVLGVD------QSEILYQAMDIIRLNKLEDTITLIKGKIEEVHLPVEKVD-VII 265
           + GA  V+G+D      ++   +++ D +   ++E  +  ++  +EE     E  D V+ 
Sbjct: 166 RLGA-SVIGIDPVDENIKTAQCHKSFDPVLDKRIEYRVCSLEEIVEET---AETFDAVVA 221

Query: 266 SEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAFWDDVY 325
           SE + + +  E+ L        + L  GGS++  I TI+   +S    +A  I F + + 
Sbjct: 222 SEVVEHVIDLETFLQCCC----QVLKPGGSLF--ITTINKTQLS----YALGIVFSEQIA 271

Query: 326 GF---KMSCMKKAVIPEAVVEVLDPKTL 350
                     +K V PE +  +L+   L
Sbjct: 272 SIVPKGTHTWEKFVSPETLESILESNGL 299


>gi|47271406 bin3, bicoid-interacting 3 [Homo sapiens]
          Length = 689

 Score = 32.7 bits (73), Expect = 0.73
 Identities = 18/50 (36%), Positives = 30/50 (60%), Gaps = 2/50 (4%)

Query: 189 PHIFKDKVVLDVGCGTGILSM-FAAKAGAKKVLGVD-QSEILYQAMDIIR 236
           P  F+ + VLD+GC  G L++  A K G  +++G+D  S +++ A   IR
Sbjct: 439 PEWFRGRDVLDLGCNVGHLTLSIACKWGPSRMVGLDIDSRLIHSARQNIR 488


>gi|239756957 PREDICTED: dynein, axonemal, heavy chain 17 [Homo
            sapiens]
          Length = 4470

 Score = 31.6 bits (70), Expect = 1.6
 Identities = 40/195 (20%), Positives = 78/195 (40%), Gaps = 17/195 (8%)

Query: 147  IADLQEDEDGVYFSSYGHYGIHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVGCGTGI 206
            +A LQ +E  +       + + +   +++ R E+   F   NP+   +K    +    GI
Sbjct: 1198 VAPLQANEVSILRRKCQQFELKQHEFRERFRREAPFSFSDPNPYKSLNKQQKSISAMEGI 1257

Query: 207  LSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEE------VHLPVEK 260
            +   +   G  +V   D  ++     ++  L +L D + ++   IE+        + VE+
Sbjct: 1258 MEALSKSGGLFEVPVPDYKQLKACHREVRLLKELWDMVVVVNTSIEDWKTTKWKDINVEQ 1317

Query: 261  VDVIISEWMGYFLLFESMLDSVLYAKNKYLAKGGSVYPDICTISLVAVSDVNKHADRIAF 320
            +D+   +    F      LD  +   + ++    +V   I   SL AVS++   A R   
Sbjct: 1318 MDIDCKK----FAKDMRSLDKEMKTWDAFVGLDNTVKNVI--TSLRAVSELQNPAIRERH 1371

Query: 321  WDDV-----YGFKMS 330
            W  +       FKMS
Sbjct: 1372 WQQLMQATQVKFKMS 1386


>gi|34222389 HpaII tiny fragments locus 9C [Homo sapiens]
          Length = 625

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 20/104 (19%)

Query: 167 IHEEMLKDKIRTESYRDFIYQNPH------IFKD-------KVVLDVGCGTGILSMFAAK 213
           IHE++L    R   +  F    P       + +D        +VLDV CGTG + +  A+
Sbjct: 393 IHEDLLGLTFRISPHAFFQVNTPAAEVLYTVIQDWAQLDAGSMVLDVCCGTGTIGLALAR 452

Query: 214 AGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIK---GKIEEV 254
              K+V+GV   E+  +A++  R+N  ++ ++ ++   G+ E++
Sbjct: 453 K-VKRVIGV---ELCPEAVEDARVNAQDNELSNVEFHCGRAEDL 492


>gi|51173878 HpaII tiny fragments locus 9C [Homo sapiens]
          Length = 625

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 27/104 (25%), Positives = 52/104 (50%), Gaps = 20/104 (19%)

Query: 167 IHEEMLKDKIRTESYRDFIYQNPH------IFKD-------KVVLDVGCGTGILSMFAAK 213
           IHE++L    R   +  F    P       + +D        +VLDV CGTG + +  A+
Sbjct: 393 IHEDLLGLTFRISPHAFFQVNTPAAEVLYTVIQDWAQLDAGSMVLDVCCGTGTIGLALAR 452

Query: 214 AGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIK---GKIEEV 254
              K+V+GV   E+  +A++  R+N  ++ ++ ++   G+ E++
Sbjct: 453 K-VKRVIGV---ELCPEAVEDARVNAQDNELSNVEFHCGRAEDL 492


>gi|45827723 hypothetical protein LOC25895 isoform b [Homo sapiens]
          Length = 149

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 13/41 (31%), Positives = 26/41 (63%)

Query: 192 FKDKVVLDVGCGTGILSMFAAKAGAKKVLGVDQSEILYQAM 232
           F+ K V+++G GTGI+ + AA  GA  ++   + +++ Q +
Sbjct: 74  FRGKKVIELGAGTGIVGILAALQGAYGLVRETEDDVIEQEL 114


>gi|58219056 methyltransferase like 10 [Homo sapiens]
          Length = 291

 Score = 31.2 bits (69), Expect = 2.1
 Identities = 34/112 (30%), Positives = 47/112 (41%), Gaps = 19/112 (16%)

Query: 151 QEDEDGVY------FSSYGHYG---IHEEMLKDKIRTESYRDFIYQNPHIFKDKVVLDVG 201
           +E  D VY      F  YG  G     EE +   IR         Q   I  D  VLD+G
Sbjct: 35  REHWDAVYERELQTFREYGDTGEIWFGEESMNRLIRW-------MQKHKIPLDASVLDIG 87

Query: 202 CGTGILSMFAAKAGAKKVLGVDQSEILYQAMDIIRLNKLEDTITLIKGKIEE 253
            G G+  +  AK G   + G+D S    Q    I + K  + ++ IK K+E+
Sbjct: 88  TGNGVFLVELAKFGFSNITGIDYSPSAIQLSGSI-IEK--EGLSNIKLKVED 136


>gi|7705409 HemK methyltransferase family member 1 [Homo sapiens]
          Length = 338

 Score = 30.8 bits (68), Expect = 2.8
 Identities = 23/80 (28%), Positives = 43/80 (53%), Gaps = 12/80 (15%)

Query: 196 VVLDVGCGTGILSM-FAAKAGAKKVLGVDQSEILYQAMDIIRLN----KLEDTITLI--- 247
           ++L+VGCG+G +S+   ++    +V+ VD+ E    A+ +   N    +L+D I +I   
Sbjct: 162 LILEVGCGSGAISLSLLSQLPQSRVIAVDKRE---AAISLTHENAQRLRLQDRIWIIHLD 218

Query: 248 -KGKIEEVHLPVEKVDVIIS 266
              +    HLP   +D+I+S
Sbjct: 219 MTSERSWTHLPWGPMDLIVS 238


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.319    0.134    0.393 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 16,542,839
Number of Sequences: 37866
Number of extensions: 697118
Number of successful extensions: 1810
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 22
Number of HSP's successfully gapped in prelim test: 15
Number of HSP's that attempted gapping in prelim test: 1768
Number of HSP's gapped (non-prelim): 41
length of query: 469
length of database: 18,247,518
effective HSP length: 106
effective length of query: 363
effective length of database: 14,233,722
effective search space: 5166841086
effective search space used: 5166841086
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 64 (29.3 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.