BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|223468634 envoplakin-like [Homo sapiens] (301 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|223468634 envoplakin-like [Homo sapiens] 617 e-177 gi|156104874 envoplakin [Homo sapiens] 377 e-105 gi|45439327 periplakin [Homo sapiens] 122 4e-28 gi|41322923 plectin 1 isoform 11 [Homo sapiens] 64 2e-10 gi|41322914 plectin 1 isoform 10 [Homo sapiens] 64 2e-10 gi|41322919 plectin 1 isoform 8 [Homo sapiens] 64 2e-10 gi|41322910 plectin 1 isoform 7 [Homo sapiens] 64 2e-10 gi|41322916 plectin 1 isoform 6 [Homo sapiens] 64 2e-10 gi|41322908 plectin 1 isoform 3 [Homo sapiens] 64 2e-10 gi|41322912 plectin 1 isoform 2 [Homo sapiens] 64 2e-10 gi|47607492 plectin 1 isoform 1 [Homo sapiens] 64 2e-10 gi|169218211 PREDICTED: similar to plectin 1, partial [Homo sapi... 63 4e-10 gi|221316624 dystonin isoform 4 [Homo sapiens] 47 2e-05 gi|221316622 dystonin isoform 3 [Homo sapiens] 47 2e-05 gi|221316618 dystonin isoform 2 [Homo sapiens] 47 2e-05 gi|34577047 dystonin isoform 1 [Homo sapiens] 47 2e-05 gi|20357504 dystonin isoform 1eB precursor [Homo sapiens] 47 2e-05 gi|34577049 dystonin isoform 1eA precursor [Homo sapiens] 47 2e-05 gi|4502443 dystonin isoform 1e precursor [Homo sapiens] 47 2e-05 gi|58530842 desmoplakin isoform II [Homo sapiens] 44 2e-04 gi|58530840 desmoplakin isoform I [Homo sapiens] 44 2e-04 gi|33188445 microfilament and actin filament cross-linker protei... 41 0.001 gi|56549694 enabled homolog isoform a [Homo sapiens] 39 0.006 gi|39930375 enabled homolog isoform b [Homo sapiens] 39 0.006 gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 37 0.021 gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] 37 0.028 gi|92091575 coiled-coil domain containing 57 [Homo sapiens] 36 0.036 gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] 36 0.048 gi|4507831 Unc-51-like kinase 1 [Homo sapiens] 35 0.062 gi|169171388 PREDICTED: hypothetical protein [Homo sapiens] 35 0.081 >gi|223468634 envoplakin-like [Homo sapiens] Length = 301 Score = 617 bits (1592), Expect = e-177 Identities = 301/301 (100%), Positives = 301/301 (100%) Query: 1 MQASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKAR 60 MQASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKAR Sbjct: 1 MQASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKAR 60 Query: 61 RLKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLR 120 RLKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLR Sbjct: 61 RLKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLR 120 Query: 121 RPVWAGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEP 180 RPVWAGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEP Sbjct: 121 RPVWAGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEP 180 Query: 181 GQPVHALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQ 240 GQPVHALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQ Sbjct: 181 GQPVHALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQ 240 Query: 241 LEEDGKRMVELRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQHVEDYSRILCPSSSP 300 LEEDGKRMVELRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQHVEDYSRILCPSSSP Sbjct: 241 LEEDGKRMVELRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQHVEDYSRILCPSSSP 300 Query: 301 H 301 H Sbjct: 301 H 301 >gi|156104874 envoplakin [Homo sapiens] Length = 2033 Score = 377 bits (969), Expect = e-105 Identities = 216/307 (70%), Positives = 232/307 (75%), Gaps = 30/307 (9%) Query: 1 MQASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKAR 60 MQA+ADQVERDILETQKRLQQDRLNSEQSQALQHQQETG SLKEAEVLLKDLFLDVDKAR Sbjct: 46 MQANADQVERDILETQKRLQQDRLNSEQSQALQHQQETGRSLKEAEVLLKDLFLDVDKAR 105 Query: 61 RLKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAG-AETEAGL 119 RLKHPQAEE EKDI+QLHERVTQECAEY ALYEKMVLPP +G R A Sbjct: 106 RLKHPQAEEIEKDIKQLHERVTQECAEYRALYEKMVLPPD------VGPRVDWARVLEQK 159 Query: 120 RRPVWAGHGGAGGTD---RGAQHR-------AEGDQRPRRAAAEPGGAGCRHHPEPIPRP 169 ++ V AG G G + + A+H A G Q R+ P A R + + Sbjct: 160 QKQVCAGQYGPGMAELEQQIAEHNILQKEIDAYGQQL--RSLVGPDAATIRSQYRDLLK- 216 Query: 170 TEGGVVARAEPGQPVHAL----QGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEH 225 A + GQ + +L QGCT QLSALAEQQRRILQQDWSDLMADPAGVRREYEH Sbjct: 217 ------AASWRGQSLGSLYTHLQGCTRQLSALAEQQRRILQQDWSDLMADPAGVRREYEH 270 Query: 226 FKQHELLSQEQSVNQLEEDGKRMVELRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQ 285 FKQHELLSQEQSVNQLE+DG+RMVELRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQ Sbjct: 271 FKQHELLSQEQSVNQLEDDGERMVELRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQ 330 Query: 286 HVEDYSR 292 HVEDY R Sbjct: 331 HVEDYRR 337 >gi|45439327 periplakin [Homo sapiens] Length = 1756 Score = 122 bits (306), Expect = 4e-28 Identities = 83/299 (27%), Positives = 147/299 (49%), Gaps = 19/299 (6%) Query: 1 MQASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKAR 60 +Q +ADQVE++I++T+ ++Q D ++ + +H+ T + ++E LL L D A+ Sbjct: 34 LQKNADQVEKNIVDTEAKMQSDLARLQEGRQPEHRDVTLQKVLDSEKLLYVLEADAAIAK 93 Query: 61 RLKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLR 120 +KHPQ + +DI QL ERVT ++ +Y V + + ++ A E + Sbjct: 94 HMKHPQGDMIAEDIRQLKERVTNLRGKHKQIYRLAV----KEVDPQVNWAALVEEKLDKL 149 Query: 121 RPVWAGHGGAGGTDRG-AQHRAEG----DQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVV 175 + + GTD H+ E + G + + + + Sbjct: 150 ------NNQSFGTDLPLVDHQVEEHNIFHNEVKAIGPHLAKDGDKEQNSELRAKYQKLLA 203 Query: 176 ARAEPGQPVHALQG----CTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHEL 231 A Q + +LQ CT +L L +Q + +Q DWSD D RR+YE+F L Sbjct: 204 ASQARQQHLSSLQDYMQRCTNELYWLDQQAKGRMQYDWSDRNLDYPSRRRQYENFINRNL 263 Query: 232 LSQEQSVNQLEEDGKRMVELRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQHVEDY 290 ++E+ +N+L +G +++ HP I+AH EA+ +W+ +LNL IC+E+ L+++EDY Sbjct: 264 EAKEERINKLHSEGDQLLAAEHPGRNSIEAHMEAVHADWKEYLNLLICEESHLKYMEDY 322 >gi|41322923 plectin 1 isoform 11 [Homo sapiens] Length = 4547 Score = 63.5 bits (153), Expect = 2e-10 Identities = 72/332 (21%), Positives = 118/332 (35%), Gaps = 50/332 (15%) Query: 1 MQASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKAR 60 +Q A E + + LQ D + Q E L +A+ +++ LF DV + Sbjct: 401 LQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVERDLDKADSMIRLLFNDVQTLK 460 Query: 61 RLKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLR 120 +HPQ E+ + + +LHER+ EY + V P + A ++ R Sbjct: 461 DGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPATQV-------AQVTLQSVQR 513 Query: 121 RP--------------VWAGH------GGAGGTD---------------------RGAQH 139 RP W G G D R Sbjct: 514 RPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRGLHQSIEEFRAKIE 573 Query: 140 RAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPVHA-LQGCTWQLSALA 198 RA D+ A C + AR + +H+ + T +L L Sbjct: 574 RARSDEGQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHSFVAAATKELMWLN 633 Query: 199 EQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVELRHPAVGP 258 E++ + DWSD + + Y + EL +E+ + +L+ G R++ HPA Sbjct: 634 EKEEEEVGFDWSDRNTNMTAKKESYSALMR-ELELKEKKIKELQNAGDRLLREDHPARPT 692 Query: 259 IQAHQEALKMEWQNFLNLCICQETQLQHVEDY 290 +++ Q AL+ +W L LC C E L+ Y Sbjct: 693 VESFQAALQTQWSWMLQLCCCIEAHLKENAAY 724 Score = 31.2 bits (69), Expect = 1.2 Identities = 58/264 (21%), Positives = 102/264 (38%), Gaps = 34/264 (12%) Query: 2 QASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARR 61 QA A Q ER+ E Q+R+Q++ + E++ A+ QQ+ S +E + L + ++ R Sbjct: 1381 QAKA-QAEREAKELQQRMQEEVVRREEA-AVDAQQQKRSIQEELQQLRQSSEAEIQAKAR 1438 Query: 62 LKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRL-GTRAGAETEAGLR 120 QAE E+ ++ E + L + R G +G L RA AE + Sbjct: 1439 ----QAEAAERSRLRIEEEI-----RVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1489 Query: 121 RPVWAGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEP 180 R +R + + QR R+A E + + A E Sbjct: 1490 RQ------AQEEAERLRRQVQDESQRKRQAEVE------------LASRVKAEAEAAREK 1531 Query: 181 GQPVHALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQ 240 + + AL+ +L AE+ R L+Q + + + EL S+ S + Sbjct: 1532 QRALQALE----ELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1587 Query: 241 LEEDGKRMVELRHPAVGPIQAHQE 264 +R ++ H AV ++ E Sbjct: 1588 KTAQLERSLQEEHVAVAQLREEAE 1611 Score = 31.2 bits (69), Expect = 1.2 Identities = 62/251 (24%), Positives = 95/251 (37%), Gaps = 40/251 (15%) Query: 7 QVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARRLKHPQ 66 Q+ER + E + Q L E + Q Q E + +EAE L+ L ++A RL+ Q Sbjct: 1591 QLERSLQEEHVAVAQ--LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR-LQ 1647 Query: 67 AEET--EKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLRRPVW 124 AEE +K + Q +E AE A RRG R E L + Sbjct: 1648 AEEVAQQKSLAQAEAEKQKEEAEREA--------RRRGKAEEQAVRQRELAEQELEKQRQ 1699 Query: 125 AGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPV 184 G AQ R +Q R AE TE G R + + Sbjct: 1700 LAEG-------TAQQRLAAEQELIRLRAE----------------TEQGEQQRQLLEEEL 1736 Query: 185 HALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEED 244 LQ + +A A Q+R+ L+ + + + A+ + ++ + E+S +LE + Sbjct: 1737 ARLQ----REAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1792 Query: 245 GKRMVELRHPA 255 R EL A Sbjct: 1793 AGRFRELAEEA 1803 >gi|41322914 plectin 1 isoform 10 [Homo sapiens] Length = 4551 Score = 63.5 bits (153), Expect = 2e-10 Identities = 72/332 (21%), Positives = 118/332 (35%), Gaps = 50/332 (15%) Query: 1 MQASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKAR 60 +Q A E + + LQ D + Q E L +A+ +++ LF DV + Sbjct: 405 LQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVERDLDKADSMIRLLFNDVQTLK 464 Query: 61 RLKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLR 120 +HPQ E+ + + +LHER+ EY + V P + A ++ R Sbjct: 465 DGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPATQV-------AQVTLQSVQR 517 Query: 121 RP--------------VWAGH------GGAGGTD---------------------RGAQH 139 RP W G G D R Sbjct: 518 RPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRGLHQSIEEFRAKIE 577 Query: 140 RAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPVHA-LQGCTWQLSALA 198 RA D+ A C + AR + +H+ + T +L L Sbjct: 578 RARSDEGQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHSFVAAATKELMWLN 637 Query: 199 EQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVELRHPAVGP 258 E++ + DWSD + + Y + EL +E+ + +L+ G R++ HPA Sbjct: 638 EKEEEEVGFDWSDRNTNMTAKKESYSALMR-ELELKEKKIKELQNAGDRLLREDHPARPT 696 Query: 259 IQAHQEALKMEWQNFLNLCICQETQLQHVEDY 290 +++ Q AL+ +W L LC C E L+ Y Sbjct: 697 VESFQAALQTQWSWMLQLCCCIEAHLKENAAY 728 Score = 31.2 bits (69), Expect = 1.2 Identities = 58/264 (21%), Positives = 102/264 (38%), Gaps = 34/264 (12%) Query: 2 QASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARR 61 QA A Q ER+ E Q+R+Q++ + E++ A+ QQ+ S +E + L + ++ R Sbjct: 1385 QAKA-QAEREAKELQQRMQEEVVRREEA-AVDAQQQKRSIQEELQQLRQSSEAEIQAKAR 1442 Query: 62 LKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRL-GTRAGAETEAGLR 120 QAE E+ ++ E + L + R G +G L RA AE + Sbjct: 1443 ----QAEAAERSRLRIEEEI-----RVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1493 Query: 121 RPVWAGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEP 180 R +R + + QR R+A E + + A E Sbjct: 1494 RQ------AQEEAERLRRQVQDESQRKRQAEVE------------LASRVKAEAEAAREK 1535 Query: 181 GQPVHALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQ 240 + + AL+ +L AE+ R L+Q + + + EL S+ S + Sbjct: 1536 QRALQALE----ELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1591 Query: 241 LEEDGKRMVELRHPAVGPIQAHQE 264 +R ++ H AV ++ E Sbjct: 1592 KTAQLERSLQEEHVAVAQLREEAE 1615 Score = 31.2 bits (69), Expect = 1.2 Identities = 62/251 (24%), Positives = 95/251 (37%), Gaps = 40/251 (15%) Query: 7 QVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARRLKHPQ 66 Q+ER + E + Q L E + Q Q E + +EAE L+ L ++A RL+ Q Sbjct: 1595 QLERSLQEEHVAVAQ--LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR-LQ 1651 Query: 67 AEET--EKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLRRPVW 124 AEE +K + Q +E AE A RRG R E L + Sbjct: 1652 AEEVAQQKSLAQAEAEKQKEEAEREA--------RRRGKAEEQAVRQRELAEQELEKQRQ 1703 Query: 125 AGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPV 184 G AQ R +Q R AE TE G R + + Sbjct: 1704 LAEG-------TAQQRLAAEQELIRLRAE----------------TEQGEQQRQLLEEEL 1740 Query: 185 HALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEED 244 LQ + +A A Q+R+ L+ + + + A+ + ++ + E+S +LE + Sbjct: 1741 ARLQ----REAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1796 Query: 245 GKRMVELRHPA 255 R EL A Sbjct: 1797 AGRFRELAEEA 1807 >gi|41322919 plectin 1 isoform 8 [Homo sapiens] Length = 4547 Score = 63.5 bits (153), Expect = 2e-10 Identities = 72/332 (21%), Positives = 118/332 (35%), Gaps = 50/332 (15%) Query: 1 MQASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKAR 60 +Q A E + + LQ D + Q E L +A+ +++ LF DV + Sbjct: 401 LQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVERDLDKADSMIRLLFNDVQTLK 460 Query: 61 RLKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLR 120 +HPQ E+ + + +LHER+ EY + V P + A ++ R Sbjct: 461 DGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPATQV-------AQVTLQSVQR 513 Query: 121 RP--------------VWAGH------GGAGGTD---------------------RGAQH 139 RP W G G D R Sbjct: 514 RPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRGLHQSIEEFRAKIE 573 Query: 140 RAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPVHA-LQGCTWQLSALA 198 RA D+ A C + AR + +H+ + T +L L Sbjct: 574 RARSDEGQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHSFVAAATKELMWLN 633 Query: 199 EQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVELRHPAVGP 258 E++ + DWSD + + Y + EL +E+ + +L+ G R++ HPA Sbjct: 634 EKEEEEVGFDWSDRNTNMTAKKESYSALMR-ELELKEKKIKELQNAGDRLLREDHPARPT 692 Query: 259 IQAHQEALKMEWQNFLNLCICQETQLQHVEDY 290 +++ Q AL+ +W L LC C E L+ Y Sbjct: 693 VESFQAALQTQWSWMLQLCCCIEAHLKENAAY 724 Score = 31.2 bits (69), Expect = 1.2 Identities = 58/264 (21%), Positives = 102/264 (38%), Gaps = 34/264 (12%) Query: 2 QASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARR 61 QA A Q ER+ E Q+R+Q++ + E++ A+ QQ+ S +E + L + ++ R Sbjct: 1381 QAKA-QAEREAKELQQRMQEEVVRREEA-AVDAQQQKRSIQEELQQLRQSSEAEIQAKAR 1438 Query: 62 LKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRL-GTRAGAETEAGLR 120 QAE E+ ++ E + L + R G +G L RA AE + Sbjct: 1439 ----QAEAAERSRLRIEEEI-----RVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1489 Query: 121 RPVWAGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEP 180 R +R + + QR R+A E + + A E Sbjct: 1490 RQ------AQEEAERLRRQVQDESQRKRQAEVE------------LASRVKAEAEAAREK 1531 Query: 181 GQPVHALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQ 240 + + AL+ +L AE+ R L+Q + + + EL S+ S + Sbjct: 1532 QRALQALE----ELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1587 Query: 241 LEEDGKRMVELRHPAVGPIQAHQE 264 +R ++ H AV ++ E Sbjct: 1588 KTAQLERSLQEEHVAVAQLREEAE 1611 Score = 31.2 bits (69), Expect = 1.2 Identities = 62/251 (24%), Positives = 95/251 (37%), Gaps = 40/251 (15%) Query: 7 QVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARRLKHPQ 66 Q+ER + E + Q L E + Q Q E + +EAE L+ L ++A RL+ Q Sbjct: 1591 QLERSLQEEHVAVAQ--LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR-LQ 1647 Query: 67 AEET--EKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLRRPVW 124 AEE +K + Q +E AE A RRG R E L + Sbjct: 1648 AEEVAQQKSLAQAEAEKQKEEAEREA--------RRRGKAEEQAVRQRELAEQELEKQRQ 1699 Query: 125 AGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPV 184 G AQ R +Q R AE TE G R + + Sbjct: 1700 LAEG-------TAQQRLAAEQELIRLRAE----------------TEQGEQQRQLLEEEL 1736 Query: 185 HALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEED 244 LQ + +A A Q+R+ L+ + + + A+ + ++ + E+S +LE + Sbjct: 1737 ARLQ----REAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1792 Query: 245 GKRMVELRHPA 255 R EL A Sbjct: 1793 AGRFRELAEEA 1803 >gi|41322910 plectin 1 isoform 7 [Homo sapiens] Length = 4515 Score = 63.5 bits (153), Expect = 2e-10 Identities = 72/332 (21%), Positives = 118/332 (35%), Gaps = 50/332 (15%) Query: 1 MQASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKAR 60 +Q A E + + LQ D + Q E L +A+ +++ LF DV + Sbjct: 369 LQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVERDLDKADSMIRLLFNDVQTLK 428 Query: 61 RLKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLR 120 +HPQ E+ + + +LHER+ EY + V P + A ++ R Sbjct: 429 DGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPATQV-------AQVTLQSVQR 481 Query: 121 RP--------------VWAGH------GGAGGTD---------------------RGAQH 139 RP W G G D R Sbjct: 482 RPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRGLHQSIEEFRAKIE 541 Query: 140 RAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPVHA-LQGCTWQLSALA 198 RA D+ A C + AR + +H+ + T +L L Sbjct: 542 RARSDEGQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHSFVAAATKELMWLN 601 Query: 199 EQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVELRHPAVGP 258 E++ + DWSD + + Y + EL +E+ + +L+ G R++ HPA Sbjct: 602 EKEEEEVGFDWSDRNTNMTAKKESYSALMR-ELELKEKKIKELQNAGDRLLREDHPARPT 660 Query: 259 IQAHQEALKMEWQNFLNLCICQETQLQHVEDY 290 +++ Q AL+ +W L LC C E L+ Y Sbjct: 661 VESFQAALQTQWSWMLQLCCCIEAHLKENAAY 692 Score = 31.2 bits (69), Expect = 1.2 Identities = 58/264 (21%), Positives = 102/264 (38%), Gaps = 34/264 (12%) Query: 2 QASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARR 61 QA A Q ER+ E Q+R+Q++ + E++ A+ QQ+ S +E + L + ++ R Sbjct: 1349 QAKA-QAEREAKELQQRMQEEVVRREEA-AVDAQQQKRSIQEELQQLRQSSEAEIQAKAR 1406 Query: 62 LKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRL-GTRAGAETEAGLR 120 QAE E+ ++ E + L + R G +G L RA AE + Sbjct: 1407 ----QAEAAERSRLRIEEEI-----RVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1457 Query: 121 RPVWAGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEP 180 R +R + + QR R+A E + + A E Sbjct: 1458 RQ------AQEEAERLRRQVQDESQRKRQAEVE------------LASRVKAEAEAAREK 1499 Query: 181 GQPVHALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQ 240 + + AL+ +L AE+ R L+Q + + + EL S+ S + Sbjct: 1500 QRALQALE----ELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1555 Query: 241 LEEDGKRMVELRHPAVGPIQAHQE 264 +R ++ H AV ++ E Sbjct: 1556 KTAQLERSLQEEHVAVAQLREEAE 1579 Score = 31.2 bits (69), Expect = 1.2 Identities = 62/251 (24%), Positives = 95/251 (37%), Gaps = 40/251 (15%) Query: 7 QVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARRLKHPQ 66 Q+ER + E + Q L E + Q Q E + +EAE L+ L ++A RL+ Q Sbjct: 1559 QLERSLQEEHVAVAQ--LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR-LQ 1615 Query: 67 AEET--EKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLRRPVW 124 AEE +K + Q +E AE A RRG R E L + Sbjct: 1616 AEEVAQQKSLAQAEAEKQKEEAEREA--------RRRGKAEEQAVRQRELAEQELEKQRQ 1667 Query: 125 AGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPV 184 G AQ R +Q R AE TE G R + + Sbjct: 1668 LAEG-------TAQQRLAAEQELIRLRAE----------------TEQGEQQRQLLEEEL 1704 Query: 185 HALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEED 244 LQ + +A A Q+R+ L+ + + + A+ + ++ + E+S +LE + Sbjct: 1705 ARLQ----REAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1760 Query: 245 GKRMVELRHPA 255 R EL A Sbjct: 1761 AGRFRELAEEA 1771 >gi|41322916 plectin 1 isoform 6 [Homo sapiens] Length = 4684 Score = 63.5 bits (153), Expect = 2e-10 Identities = 72/332 (21%), Positives = 118/332 (35%), Gaps = 50/332 (15%) Query: 1 MQASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKAR 60 +Q A E + + LQ D + Q E L +A+ +++ LF DV + Sbjct: 538 LQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVERDLDKADSMIRLLFNDVQTLK 597 Query: 61 RLKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLR 120 +HPQ E+ + + +LHER+ EY + V P + A ++ R Sbjct: 598 DGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPATQV-------AQVTLQSVQR 650 Query: 121 RP--------------VWAGH------GGAGGTD---------------------RGAQH 139 RP W G G D R Sbjct: 651 RPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRGLHQSIEEFRAKIE 710 Query: 140 RAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPVHA-LQGCTWQLSALA 198 RA D+ A C + AR + +H+ + T +L L Sbjct: 711 RARSDEGQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHSFVAAATKELMWLN 770 Query: 199 EQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVELRHPAVGP 258 E++ + DWSD + + Y + EL +E+ + +L+ G R++ HPA Sbjct: 771 EKEEEEVGFDWSDRNTNMTAKKESYSALMR-ELELKEKKIKELQNAGDRLLREDHPARPT 829 Query: 259 IQAHQEALKMEWQNFLNLCICQETQLQHVEDY 290 +++ Q AL+ +W L LC C E L+ Y Sbjct: 830 VESFQAALQTQWSWMLQLCCCIEAHLKENAAY 861 Score = 31.2 bits (69), Expect = 1.2 Identities = 58/264 (21%), Positives = 102/264 (38%), Gaps = 34/264 (12%) Query: 2 QASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARR 61 QA A Q ER+ E Q+R+Q++ + E++ A+ QQ+ S +E + L + ++ R Sbjct: 1518 QAKA-QAEREAKELQQRMQEEVVRREEA-AVDAQQQKRSIQEELQQLRQSSEAEIQAKAR 1575 Query: 62 LKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRL-GTRAGAETEAGLR 120 QAE E+ ++ E + L + R G +G L RA AE + Sbjct: 1576 ----QAEAAERSRLRIEEEI-----RVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1626 Query: 121 RPVWAGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEP 180 R +R + + QR R+A E + + A E Sbjct: 1627 RQ------AQEEAERLRRQVQDESQRKRQAEVE------------LASRVKAEAEAAREK 1668 Query: 181 GQPVHALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQ 240 + + AL+ +L AE+ R L+Q + + + EL S+ S + Sbjct: 1669 QRALQALE----ELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1724 Query: 241 LEEDGKRMVELRHPAVGPIQAHQE 264 +R ++ H AV ++ E Sbjct: 1725 KTAQLERSLQEEHVAVAQLREEAE 1748 Score = 31.2 bits (69), Expect = 1.2 Identities = 62/251 (24%), Positives = 95/251 (37%), Gaps = 40/251 (15%) Query: 7 QVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARRLKHPQ 66 Q+ER + E + Q L E + Q Q E + +EAE L+ L ++A RL+ Q Sbjct: 1728 QLERSLQEEHVAVAQ--LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR-LQ 1784 Query: 67 AEET--EKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLRRPVW 124 AEE +K + Q +E AE A RRG R E L + Sbjct: 1785 AEEVAQQKSLAQAEAEKQKEEAEREA--------RRRGKAEEQAVRQRELAEQELEKQRQ 1836 Query: 125 AGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPV 184 G AQ R +Q R AE TE G R + + Sbjct: 1837 LAEG-------TAQQRLAAEQELIRLRAE----------------TEQGEQQRQLLEEEL 1873 Query: 185 HALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEED 244 LQ + +A A Q+R+ L+ + + + A+ + ++ + E+S +LE + Sbjct: 1874 ARLQ----REAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1929 Query: 245 GKRMVELRHPA 255 R EL A Sbjct: 1930 AGRFRELAEEA 1940 >gi|41322908 plectin 1 isoform 3 [Homo sapiens] Length = 4525 Score = 63.5 bits (153), Expect = 2e-10 Identities = 72/332 (21%), Positives = 118/332 (35%), Gaps = 50/332 (15%) Query: 1 MQASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKAR 60 +Q A E + + LQ D + Q E L +A+ +++ LF DV + Sbjct: 379 LQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVERDLDKADSMIRLLFNDVQTLK 438 Query: 61 RLKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLR 120 +HPQ E+ + + +LHER+ EY + V P + A ++ R Sbjct: 439 DGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPATQV-------AQVTLQSVQR 491 Query: 121 RP--------------VWAGH------GGAGGTD---------------------RGAQH 139 RP W G G D R Sbjct: 492 RPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRGLHQSIEEFRAKIE 551 Query: 140 RAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPVHA-LQGCTWQLSALA 198 RA D+ A C + AR + +H+ + T +L L Sbjct: 552 RARSDEGQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHSFVAAATKELMWLN 611 Query: 199 EQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVELRHPAVGP 258 E++ + DWSD + + Y + EL +E+ + +L+ G R++ HPA Sbjct: 612 EKEEEEVGFDWSDRNTNMTAKKESYSALMR-ELELKEKKIKELQNAGDRLLREDHPARPT 670 Query: 259 IQAHQEALKMEWQNFLNLCICQETQLQHVEDY 290 +++ Q AL+ +W L LC C E L+ Y Sbjct: 671 VESFQAALQTQWSWMLQLCCCIEAHLKENAAY 702 Score = 31.2 bits (69), Expect = 1.2 Identities = 58/264 (21%), Positives = 102/264 (38%), Gaps = 34/264 (12%) Query: 2 QASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARR 61 QA A Q ER+ E Q+R+Q++ + E++ A+ QQ+ S +E + L + ++ R Sbjct: 1359 QAKA-QAEREAKELQQRMQEEVVRREEA-AVDAQQQKRSIQEELQQLRQSSEAEIQAKAR 1416 Query: 62 LKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRL-GTRAGAETEAGLR 120 QAE E+ ++ E + L + R G +G L RA AE + Sbjct: 1417 ----QAEAAERSRLRIEEEI-----RVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1467 Query: 121 RPVWAGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEP 180 R +R + + QR R+A E + + A E Sbjct: 1468 RQ------AQEEAERLRRQVQDESQRKRQAEVE------------LASRVKAEAEAAREK 1509 Query: 181 GQPVHALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQ 240 + + AL+ +L AE+ R L+Q + + + EL S+ S + Sbjct: 1510 QRALQALE----ELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1565 Query: 241 LEEDGKRMVELRHPAVGPIQAHQE 264 +R ++ H AV ++ E Sbjct: 1566 KTAQLERSLQEEHVAVAQLREEAE 1589 Score = 31.2 bits (69), Expect = 1.2 Identities = 62/251 (24%), Positives = 95/251 (37%), Gaps = 40/251 (15%) Query: 7 QVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARRLKHPQ 66 Q+ER + E + Q L E + Q Q E + +EAE L+ L ++A RL+ Q Sbjct: 1569 QLERSLQEEHVAVAQ--LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR-LQ 1625 Query: 67 AEET--EKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLRRPVW 124 AEE +K + Q +E AE A RRG R E L + Sbjct: 1626 AEEVAQQKSLAQAEAEKQKEEAEREA--------RRRGKAEEQAVRQRELAEQELEKQRQ 1677 Query: 125 AGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPV 184 G AQ R +Q R AE TE G R + + Sbjct: 1678 LAEG-------TAQQRLAAEQELIRLRAE----------------TEQGEQQRQLLEEEL 1714 Query: 185 HALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEED 244 LQ + +A A Q+R+ L+ + + + A+ + ++ + E+S +LE + Sbjct: 1715 ARLQ----REAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1770 Query: 245 GKRMVELRHPA 255 R EL A Sbjct: 1771 AGRFRELAEEA 1781 >gi|41322912 plectin 1 isoform 2 [Homo sapiens] Length = 4533 Score = 63.5 bits (153), Expect = 2e-10 Identities = 72/332 (21%), Positives = 118/332 (35%), Gaps = 50/332 (15%) Query: 1 MQASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKAR 60 +Q A E + + LQ D + Q E L +A+ +++ LF DV + Sbjct: 387 LQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVERDLDKADSMIRLLFNDVQTLK 446 Query: 61 RLKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLR 120 +HPQ E+ + + +LHER+ EY + V P + A ++ R Sbjct: 447 DGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPATQV-------AQVTLQSVQR 499 Query: 121 RP--------------VWAGH------GGAGGTD---------------------RGAQH 139 RP W G G D R Sbjct: 500 RPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRGLHQSIEEFRAKIE 559 Query: 140 RAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPVHA-LQGCTWQLSALA 198 RA D+ A C + AR + +H+ + T +L L Sbjct: 560 RARSDEGQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHSFVAAATKELMWLN 619 Query: 199 EQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVELRHPAVGP 258 E++ + DWSD + + Y + EL +E+ + +L+ G R++ HPA Sbjct: 620 EKEEEEVGFDWSDRNTNMTAKKESYSALMR-ELELKEKKIKELQNAGDRLLREDHPARPT 678 Query: 259 IQAHQEALKMEWQNFLNLCICQETQLQHVEDY 290 +++ Q AL+ +W L LC C E L+ Y Sbjct: 679 VESFQAALQTQWSWMLQLCCCIEAHLKENAAY 710 Score = 31.2 bits (69), Expect = 1.2 Identities = 58/264 (21%), Positives = 102/264 (38%), Gaps = 34/264 (12%) Query: 2 QASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARR 61 QA A Q ER+ E Q+R+Q++ + E++ A+ QQ+ S +E + L + ++ R Sbjct: 1367 QAKA-QAEREAKELQQRMQEEVVRREEA-AVDAQQQKRSIQEELQQLRQSSEAEIQAKAR 1424 Query: 62 LKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRL-GTRAGAETEAGLR 120 QAE E+ ++ E + L + R G +G L RA AE + Sbjct: 1425 ----QAEAAERSRLRIEEEI-----RVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1475 Query: 121 RPVWAGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEP 180 R +R + + QR R+A E + + A E Sbjct: 1476 RQ------AQEEAERLRRQVQDESQRKRQAEVE------------LASRVKAEAEAAREK 1517 Query: 181 GQPVHALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQ 240 + + AL+ +L AE+ R L+Q + + + EL S+ S + Sbjct: 1518 QRALQALE----ELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1573 Query: 241 LEEDGKRMVELRHPAVGPIQAHQE 264 +R ++ H AV ++ E Sbjct: 1574 KTAQLERSLQEEHVAVAQLREEAE 1597 Score = 31.2 bits (69), Expect = 1.2 Identities = 62/251 (24%), Positives = 95/251 (37%), Gaps = 40/251 (15%) Query: 7 QVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARRLKHPQ 66 Q+ER + E + Q L E + Q Q E + +EAE L+ L ++A RL+ Q Sbjct: 1577 QLERSLQEEHVAVAQ--LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR-LQ 1633 Query: 67 AEET--EKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLRRPVW 124 AEE +K + Q +E AE A RRG R E L + Sbjct: 1634 AEEVAQQKSLAQAEAEKQKEEAEREA--------RRRGKAEEQAVRQRELAEQELEKQRQ 1685 Query: 125 AGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPV 184 G AQ R +Q R AE TE G R + + Sbjct: 1686 LAEG-------TAQQRLAAEQELIRLRAE----------------TEQGEQQRQLLEEEL 1722 Query: 185 HALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEED 244 LQ + +A A Q+R+ L+ + + + A+ + ++ + E+S +LE + Sbjct: 1723 ARLQ----REAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1778 Query: 245 GKRMVELRHPA 255 R EL A Sbjct: 1779 AGRFRELAEEA 1789 >gi|47607492 plectin 1 isoform 1 [Homo sapiens] Length = 4574 Score = 63.5 bits (153), Expect = 2e-10 Identities = 72/332 (21%), Positives = 118/332 (35%), Gaps = 50/332 (15%) Query: 1 MQASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKAR 60 +Q A E + + LQ D + Q E L +A+ +++ LF DV + Sbjct: 428 LQMEAGLCEEQLNQADALLQSDVRLLAAGKVPQRAGEVERDLDKADSMIRLLFNDVQTLK 487 Query: 61 RLKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLR 120 +HPQ E+ + + +LHER+ EY + V P + A ++ R Sbjct: 488 DGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPATQV-------AQVTLQSVQR 540 Query: 121 RP--------------VWAGH------GGAGGTD---------------------RGAQH 139 RP W G G D R Sbjct: 541 RPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRGLHQSIEEFRAKIE 600 Query: 140 RAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPVHA-LQGCTWQLSALA 198 RA D+ A C + AR + +H+ + T +L L Sbjct: 601 RARSDEGQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHSFVAAATKELMWLN 660 Query: 199 EQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVELRHPAVGP 258 E++ + DWSD + + Y + EL +E+ + +L+ G R++ HPA Sbjct: 661 EKEEEEVGFDWSDRNTNMTAKKESYSALMR-ELELKEKKIKELQNAGDRLLREDHPARPT 719 Query: 259 IQAHQEALKMEWQNFLNLCICQETQLQHVEDY 290 +++ Q AL+ +W L LC C E L+ Y Sbjct: 720 VESFQAALQTQWSWMLQLCCCIEAHLKENAAY 751 Score = 31.2 bits (69), Expect = 1.2 Identities = 58/264 (21%), Positives = 102/264 (38%), Gaps = 34/264 (12%) Query: 2 QASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARR 61 QA A Q ER+ E Q+R+Q++ + E++ A+ QQ+ S +E + L + ++ R Sbjct: 1408 QAKA-QAEREAKELQQRMQEEVVRREEA-AVDAQQQKRSIQEELQQLRQSSEAEIQAKAR 1465 Query: 62 LKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRL-GTRAGAETEAGLR 120 QAE E+ ++ E + L + R G +G L RA AE + Sbjct: 1466 ----QAEAAERSRLRIEEEI-----RVVRLQLEATERQRGGAEGELQALRARAEEAEAQK 1516 Query: 121 RPVWAGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEP 180 R +R + + QR R+A E + + A E Sbjct: 1517 RQ------AQEEAERLRRQVQDESQRKRQAEVE------------LASRVKAEAEAAREK 1558 Query: 181 GQPVHALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQ 240 + + AL+ +L AE+ R L+Q + + + EL S+ S + Sbjct: 1559 QRALQALE----ELRLQAEEAERRLRQAEVERARQVQVALETAQRSAEAELQSKRASFAE 1614 Query: 241 LEEDGKRMVELRHPAVGPIQAHQE 264 +R ++ H AV ++ E Sbjct: 1615 KTAQLERSLQEEHVAVAQLREEAE 1638 Score = 31.2 bits (69), Expect = 1.2 Identities = 62/251 (24%), Positives = 95/251 (37%), Gaps = 40/251 (15%) Query: 7 QVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARRLKHPQ 66 Q+ER + E + Q L E + Q Q E + +EAE L+ L ++A RL+ Q Sbjct: 1618 QLERSLQEEHVAVAQ--LREEAERRAQQQAEAERAREEAERELERWQLKANEALRLR-LQ 1674 Query: 67 AEET--EKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLRRPVW 124 AEE +K + Q +E AE A RRG R E L + Sbjct: 1675 AEEVAQQKSLAQAEAEKQKEEAEREA--------RRRGKAEEQAVRQRELAEQELEKQRQ 1726 Query: 125 AGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPV 184 G AQ R +Q R AE TE G R + + Sbjct: 1727 LAEG-------TAQQRLAAEQELIRLRAE----------------TEQGEQQRQLLEEEL 1763 Query: 185 HALQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEED 244 LQ + +A A Q+R+ L+ + + + A+ + ++ + E+S +LE + Sbjct: 1764 ARLQ----REAAAATQKRQELEAELAKVRAEMEVLLASKARAEEESRSTSEKSKQRLEAE 1819 Query: 245 GKRMVELRHPA 255 R EL A Sbjct: 1820 AGRFRELAEEA 1830 >gi|169218211 PREDICTED: similar to plectin 1, partial [Homo sapiens] Length = 1369 Score = 62.8 bits (151), Expect = 4e-10 Identities = 73/332 (21%), Positives = 120/332 (36%), Gaps = 50/332 (15%) Query: 1 MQASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKAR 60 +Q A E + + LQ D + Q E L +A+ +++ LF DV + Sbjct: 534 LQMEAGLCEEQLHQADALLQSDIRLLAAGKVPQRAGEVERDLDKADSMIRLLFNDVQTLK 593 Query: 61 RLKHPQAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTRAGAETEAGLR 120 +HPQ E+ + + +LHER+ EY + V P + A ++ R Sbjct: 594 DGRHPQGEQMYRRVYRLHERLVAIRTEYNLRLKAGVAAPATQV-------AQVTLQSVQR 646 Query: 121 RP--------------VWAGH------GGAGGTDRGAQHRAEGDQRPRRAAAEPGGAG-- 158 RP W G G D + G R + E A Sbjct: 647 RPELEDSTLRYLQDLLAWVEENQHRVDGAEWGVDLPSVEAQLGSHRGLHQSIEEFQAKIE 706 Query: 159 -CRHHPEPIPRPTEGGV------------------VARAEPGQPVHA-LQGCTWQLSALA 198 R + T G AR + +H+ + T +L L Sbjct: 707 RARSDEGQLSPATRGAYRDCLGRLDLQYAKLLNSSKARLRSLESLHSFVAAATKELMWLN 766 Query: 199 EQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVELRHPAVGP 258 E++ + DWSD + + Y + EL +E+ + +L+ G R++ HPA Sbjct: 767 EKEEEEVGFDWSDRNTNMTAKKESYSALMR-ELELKEKKIKELQNAGDRLLREDHPARPT 825 Query: 259 IQAHQEALKMEWQNFLNLCICQETQLQHVEDY 290 +++ Q AL+ +W L LC C E L+ Y Sbjct: 826 VESFQAALQTQWSWMLQLCCCIEAHLKENAAY 857 >gi|221316624 dystonin isoform 4 [Homo sapiens] Length = 5526 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/99 (27%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Query: 191 TWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVE 250 T +L L E++ + DWS+ + A +++Y EL +E+++ ++E ++++ Sbjct: 738 TNELIWLNEKEEEEVAYDWSERNTNIAR-KKDYHAELMRELDQKEENIKSVQEIAEQLLL 796 Query: 251 LRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQHVED 289 HPA I+A++ A++ +W L LC C E QH+++ Sbjct: 797 ENHPARLTIEAYRAAMQTQWSWILQLCQCVE---QHIKE 832 Score = 32.0 bits (71), Expect = 0.69 Identities = 24/101 (23%), Positives = 46/101 (45%), Gaps = 7/101 (6%) Query: 1 MQASADQVERDILETQKRL-------QQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLF 53 +Q A++V+RD + + +L Q D E Q++ E + E E LL+ Sbjct: 415 LQQIANRVQRDSVICEDKLILAGNALQSDSKRLESGVQFQNEAEIAGYILECENLLRQHV 474 Query: 54 LDVDKARRLKHPQAEETEKDIEQLHERVTQECAEYCALYEK 94 +DV K+ QA++ + + +L + + E ++Y K Sbjct: 475 IDVQILIDGKYYQADQLVQRVAKLRDEIMALRNECSSVYSK 515 >gi|221316622 dystonin isoform 3 [Homo sapiens] Length = 5537 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/99 (27%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Query: 191 TWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVE 250 T +L L E++ + DWS+ + A +++Y EL +E+++ ++E ++++ Sbjct: 749 TNELIWLNEKEEEEVAYDWSERNTNIAR-KKDYHAELMRELDQKEENIKSVQEIAEQLLL 807 Query: 251 LRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQHVED 289 HPA I+A++ A++ +W L LC C E QH+++ Sbjct: 808 ENHPARLTIEAYRAAMQTQWSWILQLCQCVE---QHIKE 843 Score = 32.0 bits (71), Expect = 0.69 Identities = 24/101 (23%), Positives = 46/101 (45%), Gaps = 7/101 (6%) Query: 1 MQASADQVERDILETQKRL-------QQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLF 53 +Q A++V+RD + + +L Q D E Q++ E + E E LL+ Sbjct: 426 LQQIANRVQRDSVICEDKLILAGNALQSDSKRLESGVQFQNEAEIAGYILECENLLRQHV 485 Query: 54 LDVDKARRLKHPQAEETEKDIEQLHERVTQECAEYCALYEK 94 +DV K+ QA++ + + +L + + E ++Y K Sbjct: 486 IDVQILIDGKYYQADQLVQRVAKLRDEIMALRNECSSVYSK 526 >gi|221316618 dystonin isoform 2 [Homo sapiens] Length = 5675 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/99 (27%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Query: 191 TWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVE 250 T +L L E++ + DWS+ + A +++Y EL +E+++ ++E ++++ Sbjct: 887 TNELIWLNEKEEEEVAYDWSERNTNIAR-KKDYHAELMRELDQKEENIKSVQEIAEQLLL 945 Query: 251 LRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQHVED 289 HPA I+A++ A++ +W L LC C E QH+++ Sbjct: 946 ENHPARLTIEAYRAAMQTQWSWILQLCQCVE---QHIKE 981 Score = 32.0 bits (71), Expect = 0.69 Identities = 24/101 (23%), Positives = 46/101 (45%), Gaps = 7/101 (6%) Query: 1 MQASADQVERDILETQKRL-------QQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLF 53 +Q A++V+RD + + +L Q D E Q++ E + E E LL+ Sbjct: 564 LQQIANRVQRDSVICEDKLILAGNALQSDSKRLESGVQFQNEAEIAGYILECENLLRQHV 623 Query: 54 LDVDKARRLKHPQAEETEKDIEQLHERVTQECAEYCALYEK 94 +DV K+ QA++ + + +L + + E ++Y K Sbjct: 624 IDVQILIDGKYYQADQLVQRVAKLRDEIMALRNECSSVYSK 664 >gi|34577047 dystonin isoform 1 [Homo sapiens] Length = 5497 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/99 (27%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Query: 191 TWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVE 250 T +L L E++ + DWS+ + A +++Y EL +E+++ ++E ++++ Sbjct: 709 TNELIWLNEKEEEEVAYDWSERNTNIAR-KKDYHAELMRELDQKEENIKSVQEIAEQLLL 767 Query: 251 LRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQHVED 289 HPA I+A++ A++ +W L LC C E QH+++ Sbjct: 768 ENHPARLTIEAYRAAMQTQWSWILQLCQCVE---QHIKE 803 Score = 32.0 bits (71), Expect = 0.69 Identities = 24/101 (23%), Positives = 46/101 (45%), Gaps = 7/101 (6%) Query: 1 MQASADQVERDILETQKRL-------QQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLF 53 +Q A++V+RD + + +L Q D E Q++ E + E E LL+ Sbjct: 386 LQQIANRVQRDSVICEDKLILAGNALQSDSKRLESGVQFQNEAEIAGYILECENLLRQHV 445 Query: 54 LDVDKARRLKHPQAEETEKDIEQLHERVTQECAEYCALYEK 94 +DV K+ QA++ + + +L + + E ++Y K Sbjct: 446 IDVQILIDGKYYQADQLVQRVAKLRDEIMALRNECSSVYSK 486 >gi|20357504 dystonin isoform 1eB precursor [Homo sapiens] Length = 3062 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/99 (27%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Query: 191 TWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVE 250 T +L L E++ + DWS+ + A +++Y EL +E+++ ++E ++++ Sbjct: 383 TNELIWLNEKEEEEVAYDWSERNTNIAR-KKDYHAELMRELDQKEENIKSVQEIAEQLLL 441 Query: 251 LRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQHVED 289 HPA I+A++ A++ +W L LC C E QH+++ Sbjct: 442 ENHPARLTIEAYRAAMQTQWSWILQLCQCVE---QHIKE 477 Score = 32.0 bits (71), Expect = 0.69 Identities = 24/101 (23%), Positives = 46/101 (45%), Gaps = 7/101 (6%) Query: 1 MQASADQVERDILETQKRL-------QQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLF 53 +Q A++V+RD + + +L Q D E Q++ E + E E LL+ Sbjct: 60 LQQIANRVQRDSVICEDKLILAGNALQSDSKRLESGVQFQNEAEIAGYILECENLLRQHV 119 Query: 54 LDVDKARRLKHPQAEETEKDIEQLHERVTQECAEYCALYEK 94 +DV K+ QA++ + + +L + + E ++Y K Sbjct: 120 IDVQILIDGKYYQADQLVQRVAKLRDEIMALRNECSSVYSK 160 >gi|34577049 dystonin isoform 1eA precursor [Homo sapiens] Length = 5171 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/99 (27%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Query: 191 TWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVE 250 T +L L E++ + DWS+ + A +++Y EL +E+++ ++E ++++ Sbjct: 383 TNELIWLNEKEEEEVAYDWSERNTNIAR-KKDYHAELMRELDQKEENIKSVQEIAEQLLL 441 Query: 251 LRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQHVED 289 HPA I+A++ A++ +W L LC C E QH+++ Sbjct: 442 ENHPARLTIEAYRAAMQTQWSWILQLCQCVE---QHIKE 477 Score = 32.0 bits (71), Expect = 0.69 Identities = 24/101 (23%), Positives = 46/101 (45%), Gaps = 7/101 (6%) Query: 1 MQASADQVERDILETQKRL-------QQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLF 53 +Q A++V+RD + + +L Q D E Q++ E + E E LL+ Sbjct: 60 LQQIANRVQRDSVICEDKLILAGNALQSDSKRLESGVQFQNEAEIAGYILECENLLRQHV 119 Query: 54 LDVDKARRLKHPQAEETEKDIEQLHERVTQECAEYCALYEK 94 +DV K+ QA++ + + +L + + E ++Y K Sbjct: 120 IDVQILIDGKYYQADQLVQRVAKLRDEIMALRNECSSVYSK 160 >gi|4502443 dystonin isoform 1e precursor [Homo sapiens] Length = 2649 Score = 47.4 bits (111), Expect = 2e-05 Identities = 27/99 (27%), Positives = 55/99 (55%), Gaps = 4/99 (4%) Query: 191 TWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVE 250 T +L L E++ + DWS+ + A +++Y EL +E+++ ++E ++++ Sbjct: 383 TNELIWLNEKEEEEVAYDWSERNTNIAR-KKDYHAELMRELDQKEENIKSVQEIAEQLLL 441 Query: 251 LRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQHVED 289 HPA I+A++ A++ +W L LC C E QH+++ Sbjct: 442 ENHPARLTIEAYRAAMQTQWSWILQLCQCVE---QHIKE 477 Score = 32.0 bits (71), Expect = 0.69 Identities = 24/101 (23%), Positives = 46/101 (45%), Gaps = 7/101 (6%) Query: 1 MQASADQVERDILETQKRL-------QQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLF 53 +Q A++V+RD + + +L Q D E Q++ E + E E LL+ Sbjct: 60 LQQIANRVQRDSVICEDKLILAGNALQSDSKRLESGVQFQNEAEIAGYILECENLLRQHV 119 Query: 54 LDVDKARRLKHPQAEETEKDIEQLHERVTQECAEYCALYEK 94 +DV K+ QA++ + + +L + + E ++Y K Sbjct: 120 IDVQILIDGKYYQADQLVQRVAKLRDEIMALRNECSSVYSK 160 >gi|58530842 desmoplakin isoform II [Homo sapiens] Length = 2272 Score = 43.5 bits (101), Expect = 2e-04 Identities = 24/104 (23%), Positives = 54/104 (51%), Gaps = 1/104 (0%) Query: 187 LQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGK 246 +Q + ++ + + + L DWSD + A ++E + +L +E+ +N+L+++ Sbjct: 276 IQATSREIMWINDCEEEELLYDWSDKNTNIAQ-KQEAFSIRMSQLEVKEKELNKLKQESD 334 Query: 247 RMVELRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQHVEDY 290 ++V +HPA I+A+ + L+ +W L + C + L+ Y Sbjct: 335 QLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHLKENAAY 378 >gi|58530840 desmoplakin isoform I [Homo sapiens] Length = 2871 Score = 43.5 bits (101), Expect = 2e-04 Identities = 24/104 (23%), Positives = 54/104 (51%), Gaps = 1/104 (0%) Query: 187 LQGCTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGK 246 +Q + ++ + + + L DWSD + A ++E + +L +E+ +N+L+++ Sbjct: 276 IQATSREIMWINDCEEEELLYDWSDKNTNIAQ-KQEAFSIRMSQLEVKEKELNKLKQESD 334 Query: 247 RMVELRHPAVGPIQAHQEALKMEWQNFLNLCICQETQLQHVEDY 290 ++V +HPA I+A+ + L+ +W L + C + L+ Y Sbjct: 335 QLVLNQHPASDKIEAYMDTLQTQWSWILQITKCIDVHLKENAAY 378 >gi|33188445 microfilament and actin filament cross-linker protein isoform a [Homo sapiens] Length = 5430 Score = 40.8 bits (94), Expect = 0.001 Identities = 28/100 (28%), Positives = 50/100 (50%), Gaps = 6/100 (6%) Query: 191 TWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKRMVE 250 T +L L E++ L DWSD ++ + R + L ++Q V + +D ++ Sbjct: 690 TAELIWLNEKEEEELAYDWSDNNSNISAKRNYFSELTME--LEEKQDVFRSLQDTAELLS 747 Query: 251 LR-HPAVGPIQAHQEALKMEWQNFLNLCICQETQLQHVED 289 L HPA ++A+ A++ + Q LC+C E QHV++ Sbjct: 748 LENHPAKQTVEAYSAAVQSQLQWMKQLCLCVE---QHVKE 784 >gi|56549694 enabled homolog isoform a [Homo sapiens] Length = 591 Score = 38.9 bits (89), Expect = 0.006 Identities = 41/179 (22%), Positives = 77/179 (43%), Gaps = 11/179 (6%) Query: 6 DQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARRLKHP 65 +++ER+ LE ++RL+++RL EQ + + ++E L+ E L + L ++ RL Sbjct: 169 ERLERERLE-RERLERERLEQEQLERERQERERQERLERQERLERQERL--ERQERLDRE 225 Query: 66 QAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTR-AGAETEAGLRRPVW 124 + E E++ + ER QE E+ R ++ R + A A + P+ Sbjct: 226 RQERQERERLERLERERQE-------RERQEQLEREQLEWERERRISSAAAPASVETPLN 278 Query: 125 AGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQP 183 + G + ++ G Q ++ + P + G P P P + V PG P Sbjct: 279 SVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPP 337 >gi|39930375 enabled homolog isoform b [Homo sapiens] Length = 570 Score = 38.9 bits (89), Expect = 0.006 Identities = 41/179 (22%), Positives = 77/179 (43%), Gaps = 11/179 (6%) Query: 6 DQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARRLKHP 65 +++ER+ LE ++RL+++RL EQ + + ++E L+ E L + L ++ RL Sbjct: 169 ERLERERLE-RERLERERLEQEQLERERQERERQERLERQERLERQERL--ERQERLDRE 225 Query: 66 QAEETEKDIEQLHERVTQECAEYCALYEKMVLPPRRGIQGRLGTR-AGAETEAGLRRPVW 124 + E E++ + ER QE E+ R ++ R + A A + P+ Sbjct: 226 RQERQERERLERLERERQE-------RERQEQLEREQLEWERERRISSAAAPASVETPLN 278 Query: 125 AGHGGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQP 183 + G + ++ G Q ++ + P + G P P P + V PG P Sbjct: 279 SVLGDSSASEPGLQAASQPAETPSQQGIVLGPLAPPPPPPLPPGPAQASVALPPPPGPP 337 >gi|4503509 eukaryotic translation initiation factor 3, subunit 10 theta, 150/170kDa [Homo sapiens] Length = 1382 Score = 37.0 bits (84), Expect = 0.021 Identities = 36/167 (21%), Positives = 65/167 (38%), Gaps = 26/167 (15%) Query: 99 PRRGIQGRLGTRAGAETEAGLRRPVWAGHGGAGG------------TDRGAQHRAEGDQR 146 PRRG+ G R G + + G RR + G G DRG A+ D+ Sbjct: 1069 PRRGLDDDRGPRRGMDDDRGPRRGMDDDRGPRRGMDDDRGPRRGLDDDRGPWRNADDDRI 1128 Query: 147 PRRAAAEPGGAGCRHHPEPIPRPTEG------GVVARAEPGQPVHALQGCTWQLSALAEQ 200 PRR A + G + + R + G +R P +P+ G W+ + Sbjct: 1129 PRRGAEDDRGPWRNMDDDRLSRRADDDRFPRRGDDSRPGPWRPLVKPGG--WR------E 1180 Query: 201 QRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQLEEDGKR 247 + + ++ W RE++ K+ + +Q++ N + + +R Sbjct: 1181 KEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERER 1227 Score = 31.2 bits (69), Expect = 1.2 Identities = 19/62 (30%), Positives = 29/62 (46%), Gaps = 3/62 (4%) Query: 98 PPRRGIQGRLGTRAGAETEAGLRRPVWAGHG---GAGGTDRGAQHRAEGDQRPRRAAAEP 154 PPRRG+ G+ A+ + G RR + G G +R + A+ D+ PRR + Sbjct: 1017 PPRRGLDEDRGSWRTADEDRGPRRGMDDDRGPRRGGADDERSSWRNADDDRGPRRGLDDD 1076 Query: 155 GG 156 G Sbjct: 1077 RG 1078 Score = 28.9 bits (63), Expect = 5.8 Identities = 22/71 (30%), Positives = 27/71 (38%), Gaps = 12/71 (16%) Query: 99 PRRGIQGRLGTRAGAETEAGLRR------PVWAGHGG------AGGTDRGAQHRAEGDQR 146 PRRG+ G R G E + RR P W DRG A+ D+ Sbjct: 958 PRRGMDDDRGPRRGPEEDRFSRRGADDDRPSWRNTDDDRPPRRIADEDRGNWRHADDDRP 1017 Query: 147 PRRAAAEPGGA 157 PRR E G+ Sbjct: 1018 PRRGLDEDRGS 1028 >gi|153791497 ciliary rootlet coiled-coil [Homo sapiens] Length = 2017 Score = 36.6 bits (83), Expect = 0.028 Identities = 63/249 (25%), Positives = 102/249 (40%), Gaps = 37/249 (14%) Query: 14 ETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKARRLKHPQAEETEKD 73 E +++ Q+RL++ + QAL ++ SSL E L+ D++ R E E Sbjct: 1760 EHDRQVLQERLDAAR-QALSEARKQSSSLGEQVQTLRGEVADLELQR-------VEAEGQ 1811 Query: 74 IEQLHERVTQ-ECAEYCALYEKMVLPP-RRGIQGRLGT--RAGAETEAGLRRPVWAGHGG 129 ++QL E + Q + E AL L RR +Q RLG+ RA A+ EA R Sbjct: 1812 LQQLREVLRQRQEGEAAALNTVQKLQDERRLLQERLGSLQRALAQLEAEKRE-------- 1863 Query: 130 AGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHPEPIPRPTEGGVVARAEPGQPVHALQG 189 +R A + RR + R H + + E G + R G + Sbjct: 1864 ---VERSALRLEKDRVALRRTLDKVEREKLRSHEDTVRLSAEKGRLDRTLTGAELE---- 1916 Query: 190 CTWQLSALAEQQRRILQQDWSDLMADPAGVRREYEHFKQHELLSQEQSVNQL---EEDGK 246 LAE QR+I Q + ++ + + + E Q + L +Q V +L + + Sbjct: 1917 -------LAEAQRQIQQLEAQVVVLEQSHSPAQLEVDAQQQQLELQQEVERLRSAQAQTE 1969 Query: 247 RMVELRHPA 255 R +E R A Sbjct: 1970 RTLEARERA 1978 Score = 34.3 bits (77), Expect = 0.14 Identities = 54/208 (25%), Positives = 78/208 (37%), Gaps = 29/208 (13%) Query: 1 MQASADQVERDILETQKRLQQDR-----LNSEQSQALQHQQETGSSLKEAEVLLKDLFLD 55 ++ +VER LE ++ LQ+ R L+SE ++ + E L E K+ + Sbjct: 1264 LRTGLQEVERSRLEARRELQELRRQMKMLDSENTRLGRELAELQGRLALGERAEKESRRE 1323 Query: 56 VD--KARRLKHPQAEETEKDIEQLHERVTQE--------------CAEYCALYEKMVLPP 99 + R LK + E + Q+ +R QE E EK L Sbjct: 1324 TLGLRQRLLKGEASLEVMRQELQVAQRKLQEQEGEFRTRERRLLGSLEEARGTEKQQLDH 1383 Query: 100 RRGIQGRLGTRAGAETEAGLRRPVWAGHGGAGGTDRG-----AQHRAEGDQRPRRAAAEP 154 RG++ +L E GLR + A G A G + Q RA Q +A Sbjct: 1384 ARGLELKLEAARAEAAELGLR--LSAAEGRAQGLEAELARVEVQRRAAEAQLGGLRSALR 1441 Query: 155 GGAGCRHHPEPIPRPTEGGVVARAEPGQ 182 G G P P PRP G AR P + Sbjct: 1442 RGLGLGRAPSPAPRPVPGS-PARDAPAE 1468 >gi|92091575 coiled-coil domain containing 57 [Homo sapiens] Length = 915 Score = 36.2 bits (82), Expect = 0.036 Identities = 22/58 (37%), Positives = 34/58 (58%), Gaps = 1/58 (1%) Query: 2 QASADQVERDILETQKRLQQDRLNSEQSQALQHQQETGSSLKEAEVLLKDLFLDVDKA 59 Q D +ERD ++ + L Q L+ +SQ QET +L+E EV+LK + L+ D+A Sbjct: 431 QRRCDDIERDQIQKSEALIQG-LSMAKSQVAAKLQETEQALQEQEVVLKAVTLERDQA 487 >gi|110349772 alpha 1 type I collagen preproprotein [Homo sapiens] Length = 1464 Score = 35.8 bits (81), Expect = 0.048 Identities = 33/89 (37%), Positives = 37/89 (41%), Gaps = 7/89 (7%) Query: 98 PPRRGIQGRLGTRAGAETEAGLRRPVWAGHGGAGGTDRGAQHRA--EGDQRPRRAAAEPG 155 P G G++G R G E G RP G GA G D GA A G P PG Sbjct: 292 PGENGAPGQMGPR-GLPGERG--RPGAPGPAGARGND-GATGAAGPPGPTGPAGPPGFPG 347 Query: 156 GAGCRHHPEPI-PRPTEGGVVARAEPGQP 183 G + P PR +EG R EPG P Sbjct: 348 AVGAKGEAGPQGPRGSEGPQGVRGEPGPP 376 Score = 30.0 bits (66), Expect = 2.6 Identities = 32/93 (34%), Positives = 42/93 (45%), Gaps = 11/93 (11%) Query: 97 LPPRRGIQGRLGTRAGAETEAGLRRPVWAGHGGAGGTDR--GAQHRAE--GDQRPRRAAA 152 LP +G+ G G+ G + + G P AG G G GA+ +A G P+ AA Sbjct: 534 LPGAKGLTGSPGS-PGPDGKTGPPGP--AGQDGRPGPPGPPGARGQAGVMGFPGPKGAAG 590 Query: 153 EPGGAGCRHHPEPI----PRPTEGGVVARAEPG 181 EPG AG R P P P +G A+ PG Sbjct: 591 EPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPG 623 Score = 29.3 bits (64), Expect = 4.4 Identities = 32/94 (34%), Positives = 38/94 (40%), Gaps = 13/94 (13%) Query: 102 GIQGRLGTRAGAETEAGLR-RPVWAGHGGAGGTDRGAQHR----AEGDQRPRRAAAE--- 153 G+QG G AG E + G R P G G G G R A+G P+ A E Sbjct: 455 GVQGPPGP-AGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGS 513 Query: 154 PGGAGCRHHPEPIPRPTEGGVVA----RAEPGQP 183 PG AG + P RP E G+ PG P Sbjct: 514 PGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSP 547 >gi|4507831 Unc-51-like kinase 1 [Homo sapiens] Length = 1050 Score = 35.4 bits (80), Expect = 0.062 Identities = 26/87 (29%), Positives = 34/87 (39%), Gaps = 18/87 (20%) Query: 121 RPVWAGHGGAGGTD-RGAQHRAEGDQRPRRAAAEPGGAGCRHHPEP-----------IPR 168 RP W+G G + RG + G P + G GCR H P +P+ Sbjct: 514 RPGWSGTPSPQGAEMRGGRSPRPGSSAPEHSP-RTSGLGCRLHSAPNLSDLHVVRPKLPK 572 Query: 169 PTEGGVVA-----RAEPGQPVHALQGC 190 P + A +A P QP H LQ C Sbjct: 573 PPTDPLGAVFSPPQASPPQPSHGLQSC 599 >gi|169171388 PREDICTED: hypothetical protein [Homo sapiens] Length = 154 Score = 35.0 bits (79), Expect = 0.081 Identities = 23/55 (41%), Positives = 27/55 (49%), Gaps = 3/55 (5%) Query: 128 GGAGGTDRGAQHRAEGDQRPRRAAAEPGGAGCRHHP--EPIPRPTEG-GVVARAE 179 GG GG GA+ A G R R A G R HP EP P+ +G G ARA+ Sbjct: 52 GGGGGGAGGAEGGAGGAGRARERAESGRPCGRRRHPQAEPAPKEFQGDGAAARAD 106 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.315 0.131 0.392 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 13,141,222 Number of Sequences: 37866 Number of extensions: 698082 Number of successful extensions: 4356 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 71 Number of HSP's successfully gapped in prelim test: 258 Number of HSP's that attempted gapping in prelim test: 3902 Number of HSP's gapped (non-prelim): 716 length of query: 301 length of database: 18,247,518 effective HSP length: 102 effective length of query: 199 effective length of database: 14,385,186 effective search space: 2862652014 effective search space used: 2862652014 T: 11 A: 40 X1: 16 ( 7.3 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 41 (21.6 bits) S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.