Guide to the Human Genome
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Search of human proteins with 22202608

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|22202608 blood vessel epicardial substance isoform 4 [Homo
sapiens]
         (360 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|22202606 blood vessel epicardial substance isoform 5 [Homo sa...   735   0.0  
gi|22202608 blood vessel epicardial substance isoform 4 [Homo sa...   735   0.0  
gi|21359947 popeye protein 3 [Homo sapiens]                           149   3e-36
gi|22209004 popeye protein 2 [Homo sapiens]                           148   6e-36
gi|76781492 XPMC2 prevents mitotic catastrophe 2 homolog [Homo s...    33   0.52 
gi|51599156 chromodomain helicase DNA binding protein 4 [Homo sa...    32   0.88 
gi|37577122 ubiquitin-conjugating enzyme E2, J1 [Homo sapiens]         30   2.6  
gi|194363771 sperm specific antigen 2 isoform 1 [Homo sapiens]         29   5.7  
gi|28557788 sperm specific antigen 2 isoform 2 [Homo sapiens]          29   5.7  
gi|7662126 signal-induced proliferation-associated 1 like 1 [Hom...    29   5.7  
gi|148747351 protein kinase C and casein kinase substrate in neu...    29   5.7  
gi|110347463 human immunodeficiency virus type I enhancer bindin...    29   7.5  
gi|169234742 NACHT and WD repeat domain containing 1 [Homo sapiens]    29   7.5  
gi|56711324 HAUS augmin-like complex, subunit 3 [Homo sapiens]         28   9.8  

>gi|22202606 blood vessel epicardial substance isoform 5 [Homo
           sapiens]
          Length = 360

 Score =  735 bits (1898), Expect = 0.0
 Identities = 360/360 (100%), Positives = 360/360 (100%)

Query: 1   MNYTESSPLRESTAIGFTPELESIIPVPSNKTTCENWREIHHLVFHVANICFAVGLVIPT 60
           MNYTESSPLRESTAIGFTPELESIIPVPSNKTTCENWREIHHLVFHVANICFAVGLVIPT
Sbjct: 1   MNYTESSPLRESTAIGFTPELESIIPVPSNKTTCENWREIHHLVFHVANICFAVGLVIPT 60

Query: 61  TLHLHMIFLRGMLTLGCTLYIVWATLYRCALDIMIWNSVFLGVNILHLSYLLYKKRPVKI 120
           TLHLHMIFLRGMLTLGCTLYIVWATLYRCALDIMIWNSVFLGVNILHLSYLLYKKRPVKI
Sbjct: 61  TLHLHMIFLRGMLTLGCTLYIVWATLYRCALDIMIWNSVFLGVNILHLSYLLYKKRPVKI 120

Query: 121 EKELSGMYRRLFEPLRVPPDLFRRLTGQFCMIQTLKKGQTYAAEDKTSVDDRLSILLKGK 180
           EKELSGMYRRLFEPLRVPPDLFRRLTGQFCMIQTLKKGQTYAAEDKTSVDDRLSILLKGK
Sbjct: 121 EKELSGMYRRLFEPLRVPPDLFRRLTGQFCMIQTLKKGQTYAAEDKTSVDDRLSILLKGK 180

Query: 181 MKVSYRGHFLHNIYPCAFIDSPEFRSTQMHKGEKFQVTIIADDNCRFLCWSRERLTYFLE 240
           MKVSYRGHFLHNIYPCAFIDSPEFRSTQMHKGEKFQVTIIADDNCRFLCWSRERLTYFLE
Sbjct: 181 MKVSYRGHFLHNIYPCAFIDSPEFRSTQMHKGEKFQVTIIADDNCRFLCWSRERLTYFLE 240

Query: 241 SEPFLYEIFRYLIGKDITNKLYSLNDPTLNDKKAKKLEHQLSLCTQISMLEMRNSIASSS 300
           SEPFLYEIFRYLIGKDITNKLYSLNDPTLNDKKAKKLEHQLSLCTQISMLEMRNSIASSS
Sbjct: 241 SEPFLYEIFRYLIGKDITNKLYSLNDPTLNDKKAKKLEHQLSLCTQISMLEMRNSIASSS 300

Query: 301 DSDDGLHQFLRGTSSMSSLHVSSPHQRASAKMKPIEEGAEDDDDVFEPASPNTLKVHQLP 360
           DSDDGLHQFLRGTSSMSSLHVSSPHQRASAKMKPIEEGAEDDDDVFEPASPNTLKVHQLP
Sbjct: 301 DSDDGLHQFLRGTSSMSSLHVSSPHQRASAKMKPIEEGAEDDDDVFEPASPNTLKVHQLP 360


>gi|22202608 blood vessel epicardial substance isoform 4 [Homo
           sapiens]
          Length = 360

 Score =  735 bits (1898), Expect = 0.0
 Identities = 360/360 (100%), Positives = 360/360 (100%)

Query: 1   MNYTESSPLRESTAIGFTPELESIIPVPSNKTTCENWREIHHLVFHVANICFAVGLVIPT 60
           MNYTESSPLRESTAIGFTPELESIIPVPSNKTTCENWREIHHLVFHVANICFAVGLVIPT
Sbjct: 1   MNYTESSPLRESTAIGFTPELESIIPVPSNKTTCENWREIHHLVFHVANICFAVGLVIPT 60

Query: 61  TLHLHMIFLRGMLTLGCTLYIVWATLYRCALDIMIWNSVFLGVNILHLSYLLYKKRPVKI 120
           TLHLHMIFLRGMLTLGCTLYIVWATLYRCALDIMIWNSVFLGVNILHLSYLLYKKRPVKI
Sbjct: 61  TLHLHMIFLRGMLTLGCTLYIVWATLYRCALDIMIWNSVFLGVNILHLSYLLYKKRPVKI 120

Query: 121 EKELSGMYRRLFEPLRVPPDLFRRLTGQFCMIQTLKKGQTYAAEDKTSVDDRLSILLKGK 180
           EKELSGMYRRLFEPLRVPPDLFRRLTGQFCMIQTLKKGQTYAAEDKTSVDDRLSILLKGK
Sbjct: 121 EKELSGMYRRLFEPLRVPPDLFRRLTGQFCMIQTLKKGQTYAAEDKTSVDDRLSILLKGK 180

Query: 181 MKVSYRGHFLHNIYPCAFIDSPEFRSTQMHKGEKFQVTIIADDNCRFLCWSRERLTYFLE 240
           MKVSYRGHFLHNIYPCAFIDSPEFRSTQMHKGEKFQVTIIADDNCRFLCWSRERLTYFLE
Sbjct: 181 MKVSYRGHFLHNIYPCAFIDSPEFRSTQMHKGEKFQVTIIADDNCRFLCWSRERLTYFLE 240

Query: 241 SEPFLYEIFRYLIGKDITNKLYSLNDPTLNDKKAKKLEHQLSLCTQISMLEMRNSIASSS 300
           SEPFLYEIFRYLIGKDITNKLYSLNDPTLNDKKAKKLEHQLSLCTQISMLEMRNSIASSS
Sbjct: 241 SEPFLYEIFRYLIGKDITNKLYSLNDPTLNDKKAKKLEHQLSLCTQISMLEMRNSIASSS 300

Query: 301 DSDDGLHQFLRGTSSMSSLHVSSPHQRASAKMKPIEEGAEDDDDVFEPASPNTLKVHQLP 360
           DSDDGLHQFLRGTSSMSSLHVSSPHQRASAKMKPIEEGAEDDDDVFEPASPNTLKVHQLP
Sbjct: 301 DSDDGLHQFLRGTSSMSSLHVSSPHQRASAKMKPIEEGAEDDDDVFEPASPNTLKVHQLP 360


>gi|21359947 popeye protein 3 [Homo sapiens]
          Length = 291

 Score =  149 bits (377), Expect = 3e-36
 Identities = 87/263 (33%), Positives = 146/263 (55%), Gaps = 5/263 (1%)

Query: 34  CENWR-EIHHLVFHVANICFAVGLVIPTTLHLHMIFLRGMLTLGCTLYIVWATLYRCALD 92
           C  W+ E    ++H+A+I F VG +  +     ++++  +L LG     VWA +  CA D
Sbjct: 18  CTTWKQEAEGAIYHLASILFVVGFMGGSGF-FGLLYVFSLLGLGFLCSAVWAWVDVCAAD 76

Query: 93  IMIWNSVFLGVNILHLSYLLYKKRPVKIEKELSGMYRRLFEPLRVPPDLFRRLTGQFCMI 152
           I  WN V   +  +   ++ Y+ R +   +E   +Y  LF+PL +   +FR +     ++
Sbjct: 77  IFSWNFVLFVICFMQFVHIAYQVRSITFAREFQVLYSSLFQPLGISLPVFRTIALSSEVV 136

Query: 153 QTLKKGQTYAAEDKTSVDDRLSILLKGKMKVSYRGHFLHNIYPCAFIDSPEFRSTQMHKG 212
            TL+K   YA + KTS+D +LS+L+ G+++V+  G FLH I+P  F+DSPE+ S +  + 
Sbjct: 137 -TLEKEHCYAMQGKTSID-KLSLLVSGRIRVTVDGEFLHYIFPLQFLDSPEWDSLRPTEE 194

Query: 213 EKFQVTIIADDNCRFLCWSRERLTYFLESEPFLYEIFRYLIGKDITNKLYSLNDPTLNDK 272
             FQVT+ A+ +CR++ W R++L        ++  +F  LIG DI +KLY+LND     K
Sbjct: 195 GIFQVTLTAETDCRYVSWRRKKLYLLFAQHRYISRLFSVLIGSDIADKLYALNDRVYIGK 254

Query: 273 KAKKLEHQLSLCTQISMLEMRNS 295
           +    + +L    Q+S  E+R S
Sbjct: 255 R-YHYDIRLPNFYQMSTPEIRRS 276


>gi|22209004 popeye protein 2 [Homo sapiens]
          Length = 364

 Score =  148 bits (374), Expect = 6e-36
 Identities = 82/238 (34%), Positives = 138/238 (57%), Gaps = 6/238 (2%)

Query: 32  TTCENWRE-IHHLVFHVANICFAVGLVIPTTLHLHMIFLRGMLTLGCTLYIVWATLYRCA 90
           + C  W++ +   V+H+AN    +G +  + ++    +L G L+ G    ++W     C 
Sbjct: 16  SACIRWKQDVEGAVYHLANCLLLLGFMGGSGVY-GCFYLFGFLSAGYLCCVLWGWFSACG 74

Query: 91  LDIMIWNSVFLGVNILHLSYLLYKKRPVKIEKELSGMYRRLFEPLRVPPDLFRRLTGQFC 150
           LDI++W+ +   V +L L++L+Y+ R   + +E   +Y+ L  PL+VP   ++ +    C
Sbjct: 75  LDIVLWSFLLAVVCLLQLAHLVYRLREDTLPEEFDLLYKTLCLPLQVPLQTYKEIV-HCC 133

Query: 151 --MIQTLKKGQTYAAEDKTSVDDRLSILLKGKMKVSYRGHFLHNIYPCAFIDSPEFRSTQ 208
              + TL   QTYA E +T ++ RLS+LL G+++VS  G FLH I+P  F+DSPE+ S Q
Sbjct: 134 EEQVLTLATEQTYAVEGETPIN-RLSLLLSGRVRVSQDGQFLHYIFPYQFMDSPEWESLQ 192

Query: 209 MHKGEKFQVTIIADDNCRFLCWSRERLTYFLESEPFLYEIFRYLIGKDITNKLYSLND 266
             +   FQVT+ A+ +C ++ W R+ L   L  E ++  +F  L+G DI+ KLY+LND
Sbjct: 193 PSEEGVFQVTLTAETSCSYISWPRKSLHLLLTKERYISCLFSALLGYDISEKLYTLND 250


>gi|76781492 XPMC2 prevents mitotic catastrophe 2 homolog [Homo
           sapiens]
          Length = 422

 Score = 32.7 bits (73), Expect = 0.52
 Identities = 24/67 (35%), Positives = 35/67 (52%), Gaps = 10/67 (14%)

Query: 153 QTLKKGQTYAAEDKTSVDDRLSILLKGKMKVSYRGHFLHNIYPCAFIDSP--EFRSTQMH 210
           + LK+G     E+   V   ++ +LKG++ V   GH LHN     F+D P  + R TQ +
Sbjct: 299 ENLKQG-----EELEVVQKEVAEMLKGRILV---GHALHNDLKVLFLDHPKKKIRDTQKY 350

Query: 211 KGEKFQV 217
           K  K QV
Sbjct: 351 KPFKSQV 357


>gi|51599156 chromodomain helicase DNA binding protein 4 [Homo
           sapiens]
          Length = 1912

 Score = 32.0 bits (71), Expect = 0.88
 Identities = 27/93 (29%), Positives = 39/93 (41%), Gaps = 12/93 (12%)

Query: 266 DPTLNDKKAKKLEHQLSLCTQIS--------MLEMRNSIASSSDSDDGLHQFLRGTSSMS 317
           DP +   K +K E  L LC Q+          +E    +A  SDS+     +  G     
Sbjct: 62  DPKIPKSKRQKKERML-LCRQLGDSSGEGPEFVEEEEEVALRSDSEGS--DYTPGKKKKK 118

Query: 318 SLHVSSPHQRASAKMKPIEEGAEDDDDVFEPAS 350
            L      +++ +K K  EE  +DDDD  EP S
Sbjct: 119 KLGPKK-EKKSKSKRKEEEEEEDDDDDSKEPKS 150


>gi|37577122 ubiquitin-conjugating enzyme E2, J1 [Homo sapiens]
          Length = 318

 Score = 30.4 bits (67), Expect = 2.6
 Identities = 29/120 (24%), Positives = 50/120 (41%), Gaps = 16/120 (13%)

Query: 255 KDITNKLYSLNDPTLNDKKAKKLEHQLSLCTQ-------ISMLEMRNSIASSSDSDDGLH 307
           KD+   L S +D +  D++AK+L  Q+S   +       IS  ++ +S + +   DD   
Sbjct: 157 KDVLLPLKSGSDSSQADQEAKELARQISFKAEVNSSGKTISESDLNHSFSLTDLQDDIPT 216

Query: 308 QFLRGT---------SSMSSLHVSSPHQRASAKMKPIEEGAEDDDDVFEPASPNTLKVHQ 358
            F   T         SS +S H  +     +  M P +  A+         SP+ ++ HQ
Sbjct: 217 TFQGATASTSYGLQNSSAASFHQPTQPVAKNTSMSPRQRRAQQQSQRRLSTSPDVIQGHQ 276


>gi|194363771 sperm specific antigen 2 isoform 1 [Homo sapiens]
          Length = 1259

 Score = 29.3 bits (64), Expect = 5.7
 Identities = 16/70 (22%), Positives = 33/70 (47%), Gaps = 4/70 (5%)

Query: 263 SLNDPTLNDKKAKKLEHQLSLCTQISMLEMRNSIASSSDSDDGLHQFLRGTSSMSSLHVS 322
           + N  T N++  +   H+  L  +  ++E +      SD +   H  L  +S + S+H+S
Sbjct: 386 NFNQGTENEQSKETQSHESKLGEESGIVESK----LDSDFNISSHSELENSSELKSVHIS 441

Query: 323 SPHQRASAKM 332
           +P +   A +
Sbjct: 442 TPEKEPCAPL 451


>gi|28557788 sperm specific antigen 2 isoform 2 [Homo sapiens]
          Length = 1256

 Score = 29.3 bits (64), Expect = 5.7
 Identities = 16/70 (22%), Positives = 33/70 (47%), Gaps = 4/70 (5%)

Query: 263 SLNDPTLNDKKAKKLEHQLSLCTQISMLEMRNSIASSSDSDDGLHQFLRGTSSMSSLHVS 322
           + N  T N++  +   H+  L  +  ++E +      SD +   H  L  +S + S+H+S
Sbjct: 386 NFNQGTENEQSKETQSHESKLGEESGIVESK----LDSDFNISSHSELENSSELKSVHIS 441

Query: 323 SPHQRASAKM 332
           +P +   A +
Sbjct: 442 TPEKEPCAPL 451


>gi|7662126 signal-induced proliferation-associated 1 like 1 [Homo
            sapiens]
          Length = 1804

 Score = 29.3 bits (64), Expect = 5.7
 Identities = 28/100 (28%), Positives = 47/100 (47%), Gaps = 12/100 (12%)

Query: 258  TNKLYSLNDPTLNDKKA---KKLEHQLSLCTQISMLEMRNSIASSSDSDDGLHQFLRGTS 314
            ++++ S+ D TL  +     +K E  LSL    S  +  ++  +  +S   ++     TS
Sbjct: 1366 SSEVISMADRTLETESHGLDRKTESSLSLDIH-SKSQAGSTPLTRENSTFSINDAASHTS 1424

Query: 315  SMSSLHVSSPHQRASAKMKPIEEGAEDDDDVFEPASPNTL 354
            +MSS H +SP    SA+  P EE          PA+P+ L
Sbjct: 1425 TMSSRHSASPVVFTSARSSPKEE--------LHPAAPSQL 1456


>gi|148747351 protein kinase C and casein kinase substrate in
           neurons 2 [Homo sapiens]
          Length = 486

 Score = 29.3 bits (64), Expect = 5.7
 Identities = 15/54 (27%), Positives = 27/54 (50%)

Query: 257 ITNKLYSLNDPTLNDKKAKKLEHQLSLCTQISMLEMRNSIASSSDSDDGLHQFL 310
           I+ +  S  DP+LN ++ KKL+ ++  C Q  +        S  + D G  Q++
Sbjct: 170 ISREANSKADPSLNPEQLKKLQDKIEKCKQDVLKTKEKYEKSLKELDQGTPQYM 223


>gi|110347463 human immunodeficiency virus type I enhancer binding
            protein 2 [Homo sapiens]
          Length = 2446

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 19/76 (25%), Positives = 33/76 (43%), Gaps = 4/76 (5%)

Query: 273  KAKKLEHQLSLCTQISMLEMRNSIASSSDSD----DGLHQFLRGTSSMSSLHVSSPHQRA 328
            K    +H  S       LE+  S+ S  D++    + L    +     S   +S+ HQ +
Sbjct: 1839 KGNLTKHMKSKAHMKKCLELGVSMTSVDDTETEEAENLEDLHKAAEKHSMSSISTDHQFS 1898

Query: 329  SAKMKPIEEGAEDDDD 344
             A+    E+G ++DDD
Sbjct: 1899 DAEESDGEDGDDNDDD 1914


>gi|169234742 NACHT and WD repeat domain containing 1 [Homo sapiens]
          Length = 1429

 Score = 28.9 bits (63), Expect = 7.5
 Identities = 25/97 (25%), Positives = 36/97 (37%), Gaps = 12/97 (12%)

Query: 273 KAKKLEHQLSLCTQISMLEMRNSIASSSDSDDGLHQFLRGTSSMSSLHVSSPHQRASAKM 332
           KAK+ +   S    +   E+  S+ SS D + G   FLR    +  LH       A   +
Sbjct: 17  KAKEKQRGTSYMVAVIEWEIERSLLSSEDREQGATVFLR---EIQDLHKHILEDCALRMV 73

Query: 333 KPIEEGAEDDD---------DVFEPASPNTLKVHQLP 360
             + +G  D D                P  LK H+LP
Sbjct: 74  DRLADGCLDADAQNLLSSLKSHITDMHPGVLKTHRLP 110


>gi|56711324 HAUS augmin-like complex, subunit 3 [Homo sapiens]
          Length = 603

 Score = 28.5 bits (62), Expect = 9.8
 Identities = 18/76 (23%), Positives = 36/76 (47%), Gaps = 9/76 (11%)

Query: 258 TNKLYSLNDPTLNDKKAKKLEHQLSLCTQISMLEMRNSIASSSDSDDGLHQFLRGTSSMS 317
           T K   L  P L+DK+ +KLE ++    ++  L+++              Q +   +S  
Sbjct: 83  TCKTSDLKTPRLDDKELEKLEDEVQTLLKLKNLKIQRR---------NKCQLMASVTSHK 133

Query: 318 SLHVSSPHQRASAKMK 333
           SL +++  + A+ K+K
Sbjct: 134 SLRLNAKEEEATKKLK 149


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.323    0.137    0.417 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 13,704,160
Number of Sequences: 37866
Number of extensions: 603458
Number of successful extensions: 1321
Number of sequences better than 10.0: 14
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 9
Number of HSP's that attempted gapping in prelim test: 1311
Number of HSP's gapped (non-prelim): 16
length of query: 360
length of database: 18,247,518
effective HSP length: 103
effective length of query: 257
effective length of database: 14,347,320
effective search space: 3687261240
effective search space used: 3687261240
T: 11
A: 40
X1: 16 ( 7.5 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (22.0 bits)
S2: 62 (28.5 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
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