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Search of human proteins with 221316634
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221316634 LIM domain only 7 isoform 2 [Homo sapiens]
(1385 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221316634 LIM domain only 7 isoform 2 [Homo sapiens] 2765 0.0
gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens] 1805 0.0
gi|163310749 LIM and calponin homology domains 1 isoform e [Homo... 168 3e-41
gi|163310747 LIM and calponin homology domains 1 isoform d [Homo... 168 4e-41
gi|163310745 LIM and calponin homology domains 1 isoform c [Homo... 168 4e-41
gi|163310743 LIM and calponin homology domains 1 isoform b [Homo... 159 2e-38
gi|163310741 LIM and calponin homology domains 1 isoform a [Homo... 159 2e-38
gi|148746195 trichohyalin [Homo sapiens] 80 1e-14
gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 77 9e-14
gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 75 3e-13
gi|239745153 PREDICTED: similar to Putative golgin subfamily A m... 74 1e-12
gi|239745127 PREDICTED: similar to Putative golgin subfamily A m... 74 1e-12
gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sap... 74 1e-12
gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-li... 73 2e-12
gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapi... 69 2e-11
gi|44680105 caldesmon 1 isoform 1 [Homo sapiens] 69 2e-11
gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 67 9e-11
gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 67 1e-10
gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens] 67 2e-10
gi|239745299 PREDICTED: hypothetical protein [Homo sapiens] 66 3e-10
gi|115298682 HBxAg transactivated protein 2 [Homo sapiens] 66 3e-10
gi|116089325 splicing factor, arginine/serine-rich 12 isoform a ... 65 3e-10
gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [... 65 3e-10
gi|55741709 RNA binding motif protein 25 [Homo sapiens] 65 5e-10
gi|239752551 PREDICTED: hypothetical protein [Homo sapiens] 64 8e-10
gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo ... 64 1e-09
gi|4503509 eukaryotic translation initiation factor 3, subunit 1... 63 2e-09
gi|102467242 inner centromere protein antigens 135/155kDa isofor... 62 3e-09
gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sap... 62 5e-09
gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sap... 62 5e-09
>gi|221316634 LIM domain only 7 isoform 2 [Homo sapiens]
Length = 1385
Score = 2765 bits (7167), Expect = 0.0
Identities = 1385/1385 (100%), Positives = 1385/1385 (100%)
Query: 1 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 60
MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS
Sbjct: 1 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 60
Query: 61 PVYTEADGTFSSNQRRIWGTNVENWPTVQGTSKSSCYLEEEKAKTRSIPNIVKDDLYVRK 120
PVYTEADGTFSSNQRRIWGTNVENWPTVQGTSKSSCYLEEEKAKTRSIPNIVKDDLYVRK
Sbjct: 61 PVYTEADGTFSSNQRRIWGTNVENWPTVQGTSKSSCYLEEEKAKTRSIPNIVKDDLYVRK 120
Query: 121 LSPVMPNPGNAFDQFLPKCWTPEDVNWKRIKRETYKPWYKEFQGFSQFLLLQALQTYSDD 180
LSPVMPNPGNAFDQFLPKCWTPEDVNWKRIKRETYKPWYKEFQGFSQFLLLQALQTYSDD
Sbjct: 121 LSPVMPNPGNAFDQFLPKCWTPEDVNWKRIKRETYKPWYKEFQGFSQFLLLQALQTYSDD 180
Query: 181 ILSSETHTKIDPTSGPRLITRRKNLSYAPGYRRDDLEMAALDPDLENDDFFVRKTGAFHA 240
ILSSETHTKIDPTSGPRLITRRKNLSYAPGYRRDDLEMAALDPDLENDDFFVRKTGAFHA
Sbjct: 181 ILSSETHTKIDPTSGPRLITRRKNLSYAPGYRRDDLEMAALDPDLENDDFFVRKTGAFHA 240
Query: 241 NPYVLRAFEDFRKFSEQDDSVERDIILQCREGELVLPDLEKDDMIVRRIPAQKKEVPLSG 300
NPYVLRAFEDFRKFSEQDDSVERDIILQCREGELVLPDLEKDDMIVRRIPAQKKEVPLSG
Sbjct: 241 NPYVLRAFEDFRKFSEQDDSVERDIILQCREGELVLPDLEKDDMIVRRIPAQKKEVPLSG 300
Query: 301 APDRYHPVPFPEPWTLPPEIQAKFLCVLERTCPSKEKSNSCRILVPSYRQKKDDMLTRKI 360
APDRYHPVPFPEPWTLPPEIQAKFLCVLERTCPSKEKSNSCRILVPSYRQKKDDMLTRKI
Sbjct: 301 APDRYHPVPFPEPWTLPPEIQAKFLCVLERTCPSKEKSNSCRILVPSYRQKKDDMLTRKI 360
Query: 361 QSWKLGTTVPPISFTPGPCSEADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSM 420
QSWKLGTTVPPISFTPGPCSEADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSM
Sbjct: 361 QSWKLGTTVPPISFTPGPCSEADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSM 420
Query: 421 SDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREE 480
SDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREE
Sbjct: 421 SDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREE 480
Query: 481 IEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEAS 540
IEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEAS
Sbjct: 481 IEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEAS 540
Query: 541 YQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRST 600
YQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRST
Sbjct: 541 YQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRST 600
Query: 601 QMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVED 660
QMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVED
Sbjct: 601 QMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVED 660
Query: 661 IKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSK 720
IKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSK
Sbjct: 661 IKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPFSSLSQDQAATSK 720
Query: 721 ATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPG 780
ATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPG
Sbjct: 721 ATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPG 780
Query: 781 IFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYG 840
IFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYG
Sbjct: 781 IFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYG 840
Query: 841 KAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKAS 900
KAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKAS
Sbjct: 841 KAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKAS 900
Query: 901 ESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLL 960
ESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLL
Sbjct: 901 ESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLL 960
Query: 961 QEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSE 1020
QEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSE
Sbjct: 961 QEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSE 1020
Query: 1021 GSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQA 1080
GSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQA
Sbjct: 1021 GSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQA 1080
Query: 1081 EAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTT 1140
EAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTT
Sbjct: 1081 EAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTT 1140
Query: 1141 ELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNS 1200
ELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNS
Sbjct: 1141 ELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNS 1200
Query: 1201 WIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSR 1260
WIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSR
Sbjct: 1201 WIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFYASSSVQDFSR 1260
Query: 1261 PPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRN 1320
PPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRN
Sbjct: 1261 PPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRN 1320
Query: 1321 SVLPVSVTSEALPQELKSGSETTNCTATTAISDSNLDGQPPCDVSLHTKALLQIEEEVVA 1380
SVLPVSVTSEALPQELKSGSETTNCTATTAISDSNLDGQPPCDVSLHTKALLQIEEEVVA
Sbjct: 1321 SVLPVSVTSEALPQELKSGSETTNCTATTAISDSNLDGQPPCDVSLHTKALLQIEEEVVA 1380
Query: 1381 AHVDL 1385
AHVDL
Sbjct: 1381 AHVDL 1385
>gi|33598968 LIM domain only 7 isoform 1 [Homo sapiens]
Length = 1349
Score = 1805 bits (4676), Expect = 0.0
Identities = 930/981 (94%), Positives = 939/981 (95%), Gaps = 12/981 (1%)
Query: 352 KDDMLTRKIQSWKLGTTVP----------PISFTPGPCSEADLKRWEAIRE--ASRLRHK 399
KDDM R+I + + T +P S+ P P + + E R AS + +
Sbjct: 291 KDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWASPVYTE 350
Query: 400 KRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK 459
RLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK
Sbjct: 351 ADGTFSRLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK 410
Query: 460 WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMY 519
WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMY
Sbjct: 411 WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMY 470
Query: 520 SFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLP 579
SFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLP
Sbjct: 471 SFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLP 530
Query: 580 SQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGI 639
SQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGI
Sbjct: 531 SQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGI 590
Query: 640 SSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVT 699
SSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVT
Sbjct: 591 SSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVT 650
Query: 700 RLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRIS 759
RLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRIS
Sbjct: 651 RLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRIS 710
Query: 760 INQTPGKSLDFGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEW 819
INQTPGKSLDFGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEW
Sbjct: 711 INQTPGKSLDFGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEW 770
Query: 820 EEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSN 879
EEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSN
Sbjct: 771 EEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSN 830
Query: 880 IESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWV 939
IESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWV
Sbjct: 831 IESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWV 890
Query: 940 WDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS 999
WDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS
Sbjct: 891 WDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS 950
Query: 1000 NSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVI 1059
NSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVI
Sbjct: 951 NSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVI 1010
Query: 1060 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1119
ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP
Sbjct: 1011 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1070
Query: 1120 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAE 1179
KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAE
Sbjct: 1071 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAE 1130
Query: 1180 LERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQ 1239
LERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQ
Sbjct: 1131 LERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQ 1190
Query: 1240 PPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATT 1299
PPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATT
Sbjct: 1191 PPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVATT 1250
Query: 1300 QSPTPRSHSPSASQSGSQLRN 1320
QSPTPRSHSPSASQSGSQLRN
Sbjct: 1251 QSPTPRSHSPSASQSGSQLRN 1271
Score = 157 bits (396), Expect = 9e-38
Identities = 74/81 (91%), Positives = 77/81 (95%)
Query: 1 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 60
MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS
Sbjct: 286 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 345
Query: 61 PVYTEADGTFSSNQRRIWGTN 81
PVYTEADGTFS ++I+G N
Sbjct: 346 PVYTEADGTFSRLFQKIYGEN 366
>gi|163310749 LIM and calponin homology domains 1 isoform e [Homo
sapiens]
Length = 890
Score = 168 bits (426), Expect = 3e-41
Identities = 188/760 (24%), Positives = 327/760 (43%), Gaps = 151/760 (19%)
Query: 351 KKDDMLTRKIQSWKLGTTVPPISFTPGPCSE-----ADLKRWEAIREASRLRHKKR---L 402
KKDDM R+ + + VP + P ++ A L++ +A RE R L
Sbjct: 92 KKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPL 151
Query: 403 MVERLFQKIYGENGSKSMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK 459
ER F+ S SM D+ E+ VQ + R E++Q I +QL+E+D KWQDDLA+
Sbjct: 152 GGERPFR-------STSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLAR 204
Query: 460 WKDRRKSYTSDLQKKKEEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK--STV 512
WK RR+S + DL KK+EER+++EK + ++S KT++E++Q++E + ++
Sbjct: 205 WKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAY 264
Query: 513 PSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRV 572
+ R + +L++ T+SEA ER+E S + + ++F + +
Sbjct: 265 KNARSQEEAEGILQQ--YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLNDPNPM 320
Query: 573 TTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPF 632
L QS + A++ + +R++ ++++ + S S KT T + ++TP+P+
Sbjct: 321 K---YLRQQSLPPPKFTATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPMLTPKPY 375
Query: 633 GSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVA 692
SQ + + +++ +D NG E
Sbjct: 376 -SQPKNSQDVLKTFKVDGKVSVNG---------------------------------ETV 401
Query: 693 ATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEI------SPQREV 746
EE+ R +P SL++ Q A + S L+L ++G EI S +E+
Sbjct: 402 HREEEKERECPTVAPAHSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNSVPQEL 460
Query: 747 SRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVDDEIIA 805
+ + ++ GKS + P F +V SP F + +
Sbjct: 461 AATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSSPQ--- 517
Query: 806 INNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNL 865
+ N D K+ E M+ E LV+ ++ K SPE +
Sbjct: 518 LKNDVSEEKDQKKPENEMSGKVE---LVLS-QKVVKPKSPEPE----------------A 557
Query: 866 SVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVP 925
++T F + + +N + L NL SQ S S
Sbjct: 558 TLTFPFLDKMPEAN----------------------QLHLPNL--NSQVDSPSSEKS--- 590
Query: 926 DLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERE 985
P ++ W WD EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A++E E E
Sbjct: 591 ----PVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEE 646
Query: 986 NSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVV 1045
+Y +EE ++ + T S S+D+ T + E ++
Sbjct: 647 ERRYYEEERKIIEDTVVPFTV--------------SSSSADQLSTSSSMTEGSGTMNKI- 691
Query: 1046 HEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQ 1085
D G QD+ +++R+W++ Q + L+ ++
Sbjct: 692 --DLG-NCQDE---KQDRRWKKSFQGDDSDLLLKTRESDR 725
Score = 77.0 bits (188), Expect = 1e-13
Identities = 36/60 (60%), Positives = 48/60 (80%), Gaps = 1/60 (1%)
Query: 1 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 60
+ D KDDMS RR S EPK+A+PFN++LPNKS Q +YVPAPLRKKK ++ E+ R+SW++
Sbjct: 88 LPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAER-EEYRKSWST 146
Score = 38.1 bits (87), Expect = 0.059
Identities = 18/54 (33%), Positives = 37/54 (68%)
Query: 1040 PQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQK 1093
P+EE +++ ++ Q++L+ ER +K + +L+EE E+ + + E EE++ EE+K
Sbjct: 603 PEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERK 656
Score = 36.2 bits (82), Expect = 0.22
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 69 TFSSNQRRIWGTNVENWPTVQGTSKSSCYLEEEKAKTRSIPNIVKDDLYVRKLSPVMPNP 128
+F S R+ +V ++G+S E R +P++ KDD+ R+ S P
Sbjct: 53 SFGSRSRQTPSPDV----VLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKS 108
Query: 129 GNAFDQFLPK-----CWTPEDVNWKRIKRETY-KPW 158
F+Q+LP + P + K+ +RE Y K W
Sbjct: 109 AVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSW 144
Score = 35.0 bits (79), Expect = 0.50
Identities = 23/70 (32%), Positives = 39/70 (55%), Gaps = 5/70 (7%)
Query: 1060 ERERKWEQQLQEEQE---QKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSY 1116
E ER+ +++ Q+EQE Q+R Q E ++ K E +K Q E+E E + R+ ++
Sbjct: 604 EEERRRQEKWQQEQERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDT 661
Query: 1117 DIPKTEEASS 1126
+P T +SS
Sbjct: 662 VVPFTVSSSS 671
>gi|163310747 LIM and calponin homology domains 1 isoform d [Homo
sapiens]
Length = 902
Score = 168 bits (425), Expect = 4e-41
Identities = 188/765 (24%), Positives = 329/765 (43%), Gaps = 149/765 (19%)
Query: 351 KKDDMLTRKIQSWKLGTTVPPISFTPGPCSE-----ADLKRWEAIREASRLRHKKR---L 402
KKDDM R+ + + VP + P ++ A L++ +A RE R L
Sbjct: 92 KKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPL 151
Query: 403 MVERLFQ-----KIYGENGSKSMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQ 454
ER F+ + + S SM D+ E+ VQ + R E++Q I +QL+E+D KWQ
Sbjct: 152 GGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQ 211
Query: 455 DDLAKWKDRRKSYTSDLQKKKEEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK 509
DDLA+WK RR+S + DL KK+EER+++EK + ++S KT++E++Q++E + ++
Sbjct: 212 DDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERE 271
Query: 510 --STVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAK 567
+ R + +L++ T+SEA ER+E S + + ++F
Sbjct: 272 LHEAYKNARSQEEAEGILQQ--YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLN 327
Query: 568 REDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVV 627
+ + L QS + A++ + +R++ ++++ + S S KT T + ++
Sbjct: 328 DPNPMK---YLRQQSLPPPKFTATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPML 382
Query: 628 TPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSS 687
TP+P+ SQ + + +++ +D NG
Sbjct: 383 TPKPY-SQPKNSQDVLKTFKVDGKVSVNG------------------------------- 410
Query: 688 QKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEI------S 741
E EE+ R +P SL++ Q A + S L+L ++G EI S
Sbjct: 411 --ETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNS 467
Query: 742 PQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVD 800
+E++ + ++ GKS + P F +V SP F +
Sbjct: 468 VPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSS 527
Query: 801 DEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSE 860
+ + N D K+ E M+ E LV+ ++ K SPE +
Sbjct: 528 PQ---LKNDVSEEKDQKKPENEMSGKVE---LVLS-QKVVKPKSPEPE------------ 568
Query: 861 KSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSS 920
++T F + + +N + L NL SQ S
Sbjct: 569 ----ATLTFPFLDKMPEAN----------------------QLHLPNL--NSQVDSPSSE 600
Query: 921 DSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQ 980
S P ++ W WD EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A++
Sbjct: 601 KS-------PVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQK 653
Query: 981 EAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQP 1040
E E E +Y +EE ++ + T S S+D+ T + E
Sbjct: 654 EVEEEERRYYEEERKIIEDTVVPFTV--------------SSSSADQLSTSSSMTEGSGT 699
Query: 1041 QEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQ 1085
++ D G QD+ +++R+W++ Q + L+ ++
Sbjct: 700 MNKI---DLG-NCQDE---KQDRRWKKSFQGDDSDLLLKTRESDR 737
Score = 77.0 bits (188), Expect = 1e-13
Identities = 36/60 (60%), Positives = 48/60 (80%), Gaps = 1/60 (1%)
Query: 1 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 60
+ D KDDMS RR S EPK+A+PFN++LPNKS Q +YVPAPLRKKK ++ E+ R+SW++
Sbjct: 88 LPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAER-EEYRKSWST 146
Score = 38.1 bits (87), Expect = 0.059
Identities = 18/54 (33%), Positives = 37/54 (68%)
Query: 1040 PQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQK 1093
P+EE +++ ++ Q++L+ ER +K + +L+EE E+ + + E EE++ EE+K
Sbjct: 615 PEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERK 668
Score = 36.2 bits (82), Expect = 0.22
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 69 TFSSNQRRIWGTNVENWPTVQGTSKSSCYLEEEKAKTRSIPNIVKDDLYVRKLSPVMPNP 128
+F S R+ +V ++G+S E R +P++ KDD+ R+ S P
Sbjct: 53 SFGSRSRQTPSPDV----VLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKS 108
Query: 129 GNAFDQFLPK-----CWTPEDVNWKRIKRETY-KPW 158
F+Q+LP + P + K+ +RE Y K W
Sbjct: 109 AVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSW 144
Score = 35.0 bits (79), Expect = 0.50
Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 3/66 (4%)
Query: 1061 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPK 1120
R+ KW+Q+ QE Q+R Q E ++ K E +K Q E+E E + R+ ++ +P
Sbjct: 621 RQEKWQQE-QERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDTVVPF 677
Query: 1121 TEEASS 1126
T +SS
Sbjct: 678 TVSSSS 683
Score = 33.1 bits (74), Expect = 1.9
Identities = 61/301 (20%), Positives = 112/301 (37%), Gaps = 37/301 (12%)
Query: 1060 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1119
E ++ + +EE + +EQ + Q R+ + + + + ++ RR S D+
Sbjct: 170 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 229
Query: 1120 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1178
K EE +R K +D ++ + + K +I + R E + +
Sbjct: 230 KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 281
Query: 1179 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1237
+ E + ILQ+ +R + + E + +P I+ R S + NL S
Sbjct: 282 QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 324
Query: 1238 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1295
+LN P ++ S PPP+ +T R +S+ S KT T
Sbjct: 325 ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 377
Query: 1296 VATTQSPTPRSHSPSASQSGSQLRNSVLPVSVTSEALPQELKSGSETTNCTATTAISDSN 1355
+P P S P SQ + VSV E + +E + E +++ S
Sbjct: 378 AVPMLTPKPYS-QPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQ 436
Query: 1356 L 1356
+
Sbjct: 437 M 437
>gi|163310745 LIM and calponin homology domains 1 isoform c [Homo
sapiens]
Length = 1056
Score = 168 bits (425), Expect = 4e-41
Identities = 188/765 (24%), Positives = 329/765 (43%), Gaps = 149/765 (19%)
Query: 351 KKDDMLTRKIQSWKLGTTVPPISFTPGPCSE-----ADLKRWEAIREASRLRHKKR---L 402
KKDDM R+ + + VP + P ++ A L++ +A RE R L
Sbjct: 246 KKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPL 305
Query: 403 MVERLFQ-----KIYGENGSKSMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQ 454
ER F+ + + S SM D+ E+ VQ + R E++Q I +QL+E+D KWQ
Sbjct: 306 GGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQ 365
Query: 455 DDLAKWKDRRKSYTSDLQKKKEEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK 509
DDLA+WK RR+S + DL KK+EER+++EK + ++S KT++E++Q++E + ++
Sbjct: 366 DDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERE 425
Query: 510 --STVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAK 567
+ R + +L++ T+SEA ER+E S + + ++F
Sbjct: 426 LHEAYKNARSQEEAEGILQQ--YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLN 481
Query: 568 REDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVV 627
+ + L QS + A++ + +R++ ++++ + S S KT T + ++
Sbjct: 482 DPNPMK---YLRQQSLPPPKFTATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPML 536
Query: 628 TPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSS 687
TP+P+ SQ + + +++ +D NG
Sbjct: 537 TPKPY-SQPKNSQDVLKTFKVDGKVSVNG------------------------------- 564
Query: 688 QKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEI------S 741
E EE+ R +P SL++ Q A + S L+L ++G EI S
Sbjct: 565 --ETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNS 621
Query: 742 PQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVD 800
+E++ + ++ GKS + P F +V SP F +
Sbjct: 622 VPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSS 681
Query: 801 DEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSE 860
+ + N D K+ E M+ E LV+ ++ K SPE +
Sbjct: 682 PQ---LKNDVSEEKDQKKPENEMSGKVE---LVLS-QKVVKPKSPEPE------------ 722
Query: 861 KSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSS 920
++T F + + +N + L NL SQ S
Sbjct: 723 ----ATLTFPFLDKMPEAN----------------------QLHLPNL--NSQVDSPSSE 754
Query: 921 DSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQ 980
S P ++ W WD EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A++
Sbjct: 755 KS-------PVMTPFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQK 807
Query: 981 EAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQP 1040
E E E +Y +EE ++ + T S S+D+ T + E
Sbjct: 808 EVEEEERRYYEEERKIIEDTVVPFTV--------------SSSSADQLSTSSSMTEGSGT 853
Query: 1041 QEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQ 1085
++ D G QD+ +++R+W++ Q + L+ ++
Sbjct: 854 MNKI---DLG-NCQDE---KQDRRWKKSFQGDDSDLLLKTRESDR 891
Score = 77.0 bits (188), Expect = 1e-13
Identities = 36/60 (60%), Positives = 48/60 (80%), Gaps = 1/60 (1%)
Query: 1 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 60
+ D KDDMS RR S EPK+A+PFN++LPNKS Q +YVPAPLRKKK ++ E+ R+SW++
Sbjct: 242 LPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAER-EEYRKSWST 300
Score = 38.1 bits (87), Expect = 0.059
Identities = 18/54 (33%), Positives = 37/54 (68%)
Query: 1040 PQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQK 1093
P+EE +++ ++ Q++L+ ER +K + +L+EE E+ + + E EE++ EE+K
Sbjct: 769 PEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERK 822
Score = 36.2 bits (82), Expect = 0.22
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 69 TFSSNQRRIWGTNVENWPTVQGTSKSSCYLEEEKAKTRSIPNIVKDDLYVRKLSPVMPNP 128
+F S R+ +V ++G+S E R +P++ KDD+ R+ S P
Sbjct: 207 SFGSRSRQTPSPDV----VLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKS 262
Query: 129 GNAFDQFLPK-----CWTPEDVNWKRIKRETY-KPW 158
F+Q+LP + P + K+ +RE Y K W
Sbjct: 263 AVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSW 298
Score = 35.0 bits (79), Expect = 0.50
Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 3/66 (4%)
Query: 1061 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPK 1120
R+ KW+Q+ QE Q+R Q E ++ K E +K Q E+E E + R+ ++ +P
Sbjct: 775 RQEKWQQE-QERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDTVVPF 831
Query: 1121 TEEASS 1126
T +SS
Sbjct: 832 TVSSSS 837
Score = 33.1 bits (74), Expect = 1.9
Identities = 61/301 (20%), Positives = 112/301 (37%), Gaps = 37/301 (12%)
Query: 1060 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1119
E ++ + +EE + +EQ + Q R+ + + + + ++ RR S D+
Sbjct: 324 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 383
Query: 1120 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1178
K EE +R K +D ++ + + K +I + R E + +
Sbjct: 384 KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 435
Query: 1179 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1237
+ E + ILQ+ +R + + E + +P I+ R S + NL S
Sbjct: 436 QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 478
Query: 1238 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1295
+LN P ++ S PPP+ +T R +S+ S KT T
Sbjct: 479 ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 531
Query: 1296 VATTQSPTPRSHSPSASQSGSQLRNSVLPVSVTSEALPQELKSGSETTNCTATTAISDSN 1355
+P P S P SQ + VSV E + +E + E +++ S
Sbjct: 532 AVPMLTPKPYS-QPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQ 590
Query: 1356 L 1356
+
Sbjct: 591 M 591
>gi|163310743 LIM and calponin homology domains 1 isoform b [Homo
sapiens]
Length = 1057
Score = 159 bits (402), Expect = 2e-38
Identities = 190/767 (24%), Positives = 329/767 (42%), Gaps = 152/767 (19%)
Query: 351 KKDDMLTRKIQSWKLGTTVPPISFTPGPCSE-----ADLKRWEAIREASRLRHKKR---L 402
KKDDM R+ + + VP + P ++ A L++ +A RE R L
Sbjct: 246 KKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPL 305
Query: 403 MVERLFQ-----KIYGENGSKSMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQ 454
ER F+ + + S SM D+ E+ VQ + R E++Q I +QL+E+D KWQ
Sbjct: 306 GGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQ 365
Query: 455 DDLAKWKDRRKSYTSDLQKKKEEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK 509
DDLA+WK RR+S + DL KK+EER+++EK + ++S KT++E++Q++E + ++
Sbjct: 366 DDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERE 425
Query: 510 --STVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAK 567
+ R + +L++ T+SEA ER+E S + + ++F
Sbjct: 426 LHEAYKNARSQEEAEGILQQ--YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLN 481
Query: 568 REDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVV 627
+ + L QS + A++ + +R++ ++++ + S S KT T + ++
Sbjct: 482 DPNPMK---YLRQQSLPPPKFTATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPML 536
Query: 628 TPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSS 687
TP+P+ SQ + + +++ +D NG
Sbjct: 537 TPKPY-SQPKNSQDVLKTFKVDGKVSVNG------------------------------- 564
Query: 688 QKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEI------S 741
E EE+ R +P SL++ Q A + S L+L ++G EI S
Sbjct: 565 --ETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNS 621
Query: 742 PQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVD 800
+E++ + ++ GKS + P F +V SP F +
Sbjct: 622 VPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSS 681
Query: 801 DEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSE 860
+ + N D K+ E M+ E LV+ ++ K SPE +
Sbjct: 682 PQ---LKNDVSEEKDQKKPENEMSGKVE---LVLS-QKVVKPKSPEPE------------ 722
Query: 861 KSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSS 920
++T F + + +N + L NL SQ S
Sbjct: 723 ----ATLTFPFLDKMPEAN----------------------QLHLPNL--NSQVDSPSSE 754
Query: 921 DSVVPDLPVPTISAPSRWVW--DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRA 978
S PV T P W D EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A
Sbjct: 755 KS-----PVMT---PQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKA 806
Query: 979 KQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERR 1038
++E E E +Y +EE ++ + T S S+D+ T + E
Sbjct: 807 QKEVEEEERRYYEEERKIIEDTVVPFTV--------------SSSSADQLSTSSSMTEGS 852
Query: 1039 QPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQ 1085
++ D G QD+ +++R+W++ Q + L+ ++
Sbjct: 853 GTMNKI---DLG-NCQDE---KQDRRWKKSFQGDDSDLLLKTRESDR 892
Score = 77.0 bits (188), Expect = 1e-13
Identities = 36/60 (60%), Positives = 48/60 (80%), Gaps = 1/60 (1%)
Query: 1 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 60
+ D KDDMS RR S EPK+A+PFN++LPNKS Q +YVPAPLRKKK ++ E+ R+SW++
Sbjct: 242 LPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAER-EEYRKSWST 300
Score = 38.1 bits (87), Expect = 0.059
Identities = 18/54 (33%), Positives = 37/54 (68%)
Query: 1040 PQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQK 1093
P+EE +++ ++ Q++L+ ER +K + +L+EE E+ + + E EE++ EE+K
Sbjct: 770 PEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERK 823
Score = 36.2 bits (82), Expect = 0.22
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 69 TFSSNQRRIWGTNVENWPTVQGTSKSSCYLEEEKAKTRSIPNIVKDDLYVRKLSPVMPNP 128
+F S R+ +V ++G+S E R +P++ KDD+ R+ S P
Sbjct: 207 SFGSRSRQTPSPDV----VLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKS 262
Query: 129 GNAFDQFLPK-----CWTPEDVNWKRIKRETY-KPW 158
F+Q+LP + P + K+ +RE Y K W
Sbjct: 263 AVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSW 298
Score = 35.0 bits (79), Expect = 0.50
Identities = 22/66 (33%), Positives = 36/66 (54%), Gaps = 3/66 (4%)
Query: 1061 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPK 1120
R+ KW+Q+ QE Q+R Q E ++ K E +K Q E+E E + R+ ++ +P
Sbjct: 776 RQEKWQQE-QERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDTVVPF 832
Query: 1121 TEEASS 1126
T +SS
Sbjct: 833 TVSSSS 838
Score = 33.1 bits (74), Expect = 1.9
Identities = 61/301 (20%), Positives = 112/301 (37%), Gaps = 37/301 (12%)
Query: 1060 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1119
E ++ + +EE + +EQ + Q R+ + + + + ++ RR S D+
Sbjct: 324 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 383
Query: 1120 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1178
K EE +R K +D ++ + + K +I + R E + +
Sbjct: 384 KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 435
Query: 1179 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1237
+ E + ILQ+ +R + + E + +P I+ R S + NL S
Sbjct: 436 QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 478
Query: 1238 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1295
+LN P ++ S PPP+ +T R +S+ S KT T
Sbjct: 479 ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 531
Query: 1296 VATTQSPTPRSHSPSASQSGSQLRNSVLPVSVTSEALPQELKSGSETTNCTATTAISDSN 1355
+P P S P SQ + VSV E + +E + E +++ S
Sbjct: 532 AVPMLTPKPYS-QPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQ 590
Query: 1356 L 1356
+
Sbjct: 591 M 591
>gi|163310741 LIM and calponin homology domains 1 isoform a [Homo
sapiens]
Length = 1083
Score = 159 bits (402), Expect = 2e-38
Identities = 190/767 (24%), Positives = 329/767 (42%), Gaps = 152/767 (19%)
Query: 351 KKDDMLTRKIQSWKLGTTVPPISFTPGPCSE-----ADLKRWEAIREASRLRHKKR---L 402
KKDDM R+ + + VP + P ++ A L++ +A RE R L
Sbjct: 246 KKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSWSTATSPL 305
Query: 403 MVERLFQ-----KIYGENGSKSMSDVSAED---VQNLRQLRYEEMQKIKSQLKEQDQKWQ 454
ER F+ + + S SM D+ E+ VQ + R E++Q I +QL+E+D KWQ
Sbjct: 306 GGERPFRYGPRTPVSDDAESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQ 365
Query: 455 DDLAKWKDRRKSYTSDLQKKKEEREEIEK-----QALEKSKRSSKTFKEMLQDRESQNQK 509
DDLA+WK RR+S + DL KK+EER+++EK + ++S KT++E++Q++E + ++
Sbjct: 366 DDLARWKSRRRSVSQDLIKKEEERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERE 425
Query: 510 --STVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAK 567
+ R + +L++ T+SEA ER+E S + + ++F
Sbjct: 426 LHEAYKNARSQEEAEGILQQ--YIERFTISEAVL--ERLEMPKILERSHSTEPNLSSFLN 481
Query: 568 REDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVV 627
+ + L QS + A++ + +R++ ++++ + S S KT T + ++
Sbjct: 482 DPNPMK---YLRQQSLPPPKFTATVETTIARASVLDTSMSAGS--GSPSKTVTPKAVPML 536
Query: 628 TPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSS 687
TP+P+ SQ + + +++ +D NG
Sbjct: 537 TPKPY-SQPKNSQDVLKTFKVDGKVSVNG------------------------------- 564
Query: 688 QKEVAATEEDVTRLPSPTSPFSSLSQDQAATSKATLSSTSGLDLMSESGEGEI------S 741
E EE+ R +P SL++ Q A + S L+L ++G EI S
Sbjct: 565 --ETVHREEEKERECPTVAPAHSLTKSQMFEGVARVHG-SPLELKQDNGSIEINIKKPNS 621
Query: 742 PQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASVEAGSP-AEFSQLQVD 800
+E++ + ++ GKS + P F +V SP F +
Sbjct: 622 VPQELAATTEKTEPNSQEDKNDGGKSRKGNIELASSEPQHFTTTVTRCSPTVAFVEFPSS 681
Query: 801 DEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSE 860
+ + N D K+ E M+ E LV+ ++ K SPE +
Sbjct: 682 PQ---LKNDVSEEKDQKKPENEMSGKVE---LVLS-QKVVKPKSPEPE------------ 722
Query: 861 KSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSS 920
++T F + + +N + L NL SQ S
Sbjct: 723 ----ATLTFPFLDKMPEAN----------------------QLHLPNL--NSQVDSPSSE 754
Query: 921 DSVVPDLPVPTISAPSRWVW--DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRA 978
S PV T P W D EEER+RQE+WQ+EQ+RLLQE+YQ+EQ+KL+EEW++A
Sbjct: 755 KS-----PVMT---PQFKFWAWDPEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKA 806
Query: 979 KQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERR 1038
++E E E +Y +EE ++ + T S S+D+ T + E
Sbjct: 807 QKEVEEEERRYYEEERKIIEDTVVPFTV--------------SSSSADQLSTSSSMTEGS 852
Query: 1039 QPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQ 1085
++ D G QD+ +++R+W++ Q + L+ ++
Sbjct: 853 GTMNKI---DLG-NCQDE---KQDRRWKKSFQGDDSDLLLKTRESDR 892
Score = 77.0 bits (188), Expect = 1e-13
Identities = 36/60 (60%), Positives = 48/60 (80%), Gaps = 1/60 (1%)
Query: 1 MQDYNKDDMSYRRISAVEPKTALPFNRFLPNKSRQPSYVPAPLRKKKPDKHEDNRRSWAS 60
+ D KDDMS RR S EPK+A+PFN++LPNKS Q +YVPAPLRKKK ++ E+ R+SW++
Sbjct: 242 LPDVKKDDMSARRTSHGEPKSAVPFNQYLPNKSNQTAYVPAPLRKKKAER-EEYRKSWST 300
Score = 38.1 bits (87), Expect = 0.059
Identities = 18/54 (33%), Positives = 37/54 (68%)
Query: 1040 PQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQK 1093
P+EE +++ ++ Q++L+ ER +K + +L+EE E+ + + E EE++ EE+K
Sbjct: 770 PEEERRRQEKWQQEQERLLQERYQKEQDKLKEEWEKAQKEVEEEERRYYEEERK 823
Score = 37.4 bits (85), Expect = 0.10
Identities = 62/264 (23%), Positives = 110/264 (41%), Gaps = 27/264 (10%)
Query: 1061 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPK 1120
R+ KW+Q+ QE Q+R Q E ++ K E +K Q E+E E + R+ ++ +P
Sbjct: 776 RQEKWQQE-QERLLQERYQKEQDKLKE--EWEKAQKEVEEEERRYYEEERKIIEDTVVPF 832
Query: 1121 TEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAEL 1180
T +SS D+ + S+ T +G +D +GN ++ + ++ G
Sbjct: 833 TVSSSS----ADQLSTSSS------MTEGSGTMNKID-LGNCQDEKQDRRWKKSFQG--- 878
Query: 1181 ERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNS---W 1237
+ +L + R+ L S + + + + + PVS G+ + +P +
Sbjct: 879 DDSDLLLKTRESDRLEEKGS-LTEGALAHSGNPVS-KGVHEDHQLDTEAGAPHCGTNPQL 936
Query: 1238 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPPPSAGSVKTSTTGVA 1297
Q P NQ T SS + +P + S + +PS + G
Sbjct: 937 AQDPSQNQQTSNPTHSS--EDVKPKTLPLDKSINHQIESPSER---RKKSPREHFQAGPF 991
Query: 1298 TTQSPTPRSHSPSASQSGSQLRNS 1321
+ SPTP SP+ S SG +L +S
Sbjct: 992 SPCSPTPPGQSPNRSISGKKLCSS 1015
Score = 36.2 bits (82), Expect = 0.22
Identities = 26/96 (27%), Positives = 43/96 (44%), Gaps = 10/96 (10%)
Query: 69 TFSSNQRRIWGTNVENWPTVQGTSKSSCYLEEEKAKTRSIPNIVKDDLYVRKLSPVMPNP 128
+F S R+ +V ++G+S E R +P++ KDD+ R+ S P
Sbjct: 207 SFGSRSRQTPSPDV----VLRGSSDGRGSDSESDLPHRKLPDVKKDDMSARRTSHGEPKS 262
Query: 129 GNAFDQFLPK-----CWTPEDVNWKRIKRETY-KPW 158
F+Q+LP + P + K+ +RE Y K W
Sbjct: 263 AVPFNQYLPNKSNQTAYVPAPLRKKKAEREEYRKSW 298
Score = 33.1 bits (74), Expect = 1.9
Identities = 61/301 (20%), Positives = 112/301 (37%), Gaps = 37/301 (12%)
Query: 1060 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1119
E ++ + +EE + +EQ + Q R+ + + + + ++ RR S D+
Sbjct: 324 ESTSMFDMRCEEEAAVQPHSRARQEQLQLINNQLREEDDKWQDDLARWKSRRRSVSQDLI 383
Query: 1120 KTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSG-A 1178
K EE +R K +D ++ + + K +I + R E + +
Sbjct: 384 KKEE--------ERKKMEKLLAGEDGTSERRKSIKTYREIVQEKERRERELHEAYKNARS 435
Query: 1179 ELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGESLD-NLDSPRSNSW 1237
+ E + ILQ+ +R + + E + +P I+ R S + NL S
Sbjct: 436 QEEAEGILQQYIERFTI-----------SEAVLERLEMPKILERSHSTEPNLSS------ 478
Query: 1238 RQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNP--SSSVPPPSAGSVKTSTTG 1295
+LN P ++ S PPP+ +T R +S+ S KT T
Sbjct: 479 ----FLNDPN---PMKYLRQQSLPPPKFTATVETTIARASVLDTSMSAGSGSPSKTVTPK 531
Query: 1296 VATTQSPTPRSHSPSASQSGSQLRNSVLPVSVTSEALPQELKSGSETTNCTATTAISDSN 1355
+P P S P SQ + VSV E + +E + E +++ S
Sbjct: 532 AVPMLTPKPYS-QPKNSQDVLKTFKVDGKVSVNGETVHREEEKERECPTVAPAHSLTKSQ 590
Query: 1356 L 1356
+
Sbjct: 591 M 591
>gi|148746195 trichohyalin [Homo sapiens]
Length = 1943
Score = 80.5 bits (197), Expect = 1e-14
Identities = 70/294 (23%), Positives = 136/294 (46%), Gaps = 17/294 (5%)
Query: 942 QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNS 1001
+E++ +R+++ ++EQ +++ +REQ+ RE+ R +Q+ RE + E+
Sbjct: 385 REQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERRE 444
Query: 1002 MSLTTREPSLATW----EATWSEGSKSSDREGTRAGEEERRQ---PQEEVVHEDQGKKPQ 1054
L + W E T + ++ R EEERR+ EE +Q ++ +
Sbjct: 445 QRLKREQEERRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERRE 504
Query: 1055 DQLVIERERKWEQQLQEEQEQKRLQ--AEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP 1112
QL E+E + EQ+L+ ++E++RLQ +E+Q R +E++R+ ++RE R+ Q RR
Sbjct: 505 QQLRREQEERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERR- 563
Query: 1113 VDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKE 1172
+ + EE L R + R L + +++ + +RR ++
Sbjct: 564 -EQRLKREQEERRDQLL--KREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRL 620
Query: 1173 QVPSGAELERQQIL----QEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRR 1222
+ E RQQ+L QE R++ L + R++ +E L ++R
Sbjct: 621 KREEPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKR 674
Score = 70.5 bits (171), Expect = 1e-11
Identities = 53/172 (30%), Positives = 88/172 (51%), Gaps = 10/172 (5%)
Query: 945 ERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSL 1004
E K+Q+R ++ QDR+ QE+ ++E K RE R ++E +E EL L
Sbjct: 224 EEKQQQR-RERQDRVFQEEEEKEWRK-RETVLRKEEEKLQEEEPQRQRELQEEEEQLRKL 281
Query: 1005 TTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEE-----VVHEDQGKKPQDQLVI 1059
+E E + +++ R EEERR+ QEE E Q ++ + QL
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRR 341
Query: 1060 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRR 1111
E+E + EQQL+ EQE++R + ++ +R EE++R+ ++ RE +R Q R
Sbjct: 342 EQEERREQQLRREQEEERRE---QQLRREQEEERREQQLRREQQLRREQQLR 390
Score = 69.7 bits (169), Expect = 2e-11
Identities = 66/255 (25%), Positives = 121/255 (47%), Gaps = 42/255 (16%)
Query: 942 QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNS 1001
Q EER+++ R ++E+ +E+ Q+E+E+L E + ++ ERE D++ L
Sbjct: 914 QREEREKRRRQEQERQYREEEQLQQEEEQLLREEREKRRRQERERQYRKDKK---LQQKE 970
Query: 1002 MSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIER 1061
L EP E + +RE EEE +Q +E+++ E++ K+ R
Sbjct: 971 EQLLGEEP----------EKRRRQEREKKYREEEELQQEEEQLLREEREKR--------R 1012
Query: 1062 ERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKT 1121
++WE+Q +++ E LQ E E+ R E++R E ER QYR + ++ +
Sbjct: 1013 RQEWERQYRKKDE---LQQEEEQLLREEREKRRLQERER-------QYR---EEEELQQE 1059
Query: 1122 EEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRR--SKKEQVPSGAE 1179
EE L G+ ++R EL+ + + +Q+ +RR ++ Q E
Sbjct: 1060 EEQ----LLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEE 1115
Query: 1180 L--ERQQILQEMRKR 1192
L E +Q+L+E R++
Sbjct: 1116 LQQEEEQLLREEREK 1130
Score = 68.9 bits (167), Expect = 3e-11
Identities = 66/275 (24%), Positives = 126/275 (45%), Gaps = 24/275 (8%)
Query: 942 QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEA-----ERENSKYLDEELMV 996
QEEE + Q+R + EQ +++ +REQ REE +R +QE +RE + D+ L
Sbjct: 522 QEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKR 581
Query: 997 LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEE-----VVHEDQGK 1051
RE + E + ++E R +R +P+EE + E+Q +
Sbjct: 582 EEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEPEEERRQQLLKSEEQEE 641
Query: 1052 KPQDQLVIERERKWEQQLQEEQEQKRLQ----AEAEEQKRP---AEEQKRQAEIERETSV 1104
+ Q QL E++ + EQ+L+ E+E++RL+ E EE++R AEE++ QA ++ +
Sbjct: 642 RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIKSRI 701
Query: 1105 RIYQYR-------RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLD 1157
+Q++ R Y P+ +E + + R +EL + + +
Sbjct: 702 PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQWQEEERAHRQQQEE 761
Query: 1158 QIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKR 1192
+ + Q +++++ L + L+E R+R
Sbjct: 762 EQRRDFTWQWQAEEKSERGRQRLSARPPLREQRER 796
Score = 68.9 bits (167), Expect = 3e-11
Identities = 68/262 (25%), Positives = 127/262 (48%), Gaps = 34/262 (12%)
Query: 941 DQEEERKRQERWQKEQDRLLQEKYQREQEKL---------REEWQRAKQEAERENSKYLD 991
++ E+R+RQER +K ++ +E+ Q+E+E+L R+EW+R Q +++ + +
Sbjct: 976 EEPEKRRRQEREKKYRE---EEELQQEEEQLLREEREKRRRQEWER--QYRKKDELQQEE 1030
Query: 992 EELMVLSSNSMSLTTREPSLATWEATWSEGSK--SSDREGTRAGEEERRQPQEEVVHEDQ 1049
E+L+ L RE E E + +RE R E ER+ +EE + +++
Sbjct: 1031 EQLLREEREKRRLQERERQYREEEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEE 1090
Query: 1050 GKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQY 1109
+ +++ R ++ E+Q +EE+E LQ E E+ R E++R+ E+ER QY
Sbjct: 1091 EQLLREEPEKRRRQERERQCREEEE---LQQEEEQLLREEREKRRRQELER-------QY 1140
Query: 1110 RRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRS 1169
R + ++ + EE L + + R EL+ + + +Q+ +RR
Sbjct: 1141 R---EEEEVQQEEEQ----LLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ 1193
Query: 1170 KKE-QVPSGAELERQQILQEMR 1190
++E Q EL+RQ+ Q R
Sbjct: 1194 ERERQYREEEELQRQKRKQRYR 1215
Score = 68.6 bits (166), Expect = 4e-11
Identities = 63/277 (22%), Positives = 119/277 (42%), Gaps = 26/277 (9%)
Query: 941 DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 1000
+QE E E ++Q+RL Q QR E+L W++ ++ ERE + +E+L +
Sbjct: 143 EQERELAEGEEQSEKQERLEQRDRQRRDEEL---WRQRQEWQEREERRAEEEQLQSCKGH 199
Query: 1001 SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK--------- 1051
E L E R+G +++RR+ Q+ V E++ K
Sbjct: 200 ETEEFPDEEQLRRRELL------ELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVL 253
Query: 1052 KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRR 1111
+ +++ + E E + +++LQEE+EQ R E ++ EE+++Q + RE Q RR
Sbjct: 254 RKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE-----QQLRR 308
Query: 1112 PVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKK 1171
+ + EE ++ + R +L + +Q Q R ++
Sbjct: 309 KQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQEEERREQQLRREQ 368
Query: 1172 EQVPSGAELERQQIL---QEMRKRTPLHNDNSWIRQR 1205
E+ +L R+Q L Q++R+ L + R++
Sbjct: 369 EEERREQQLRREQQLRREQQLRREQQLRREQQLRREQ 405
Score = 68.2 bits (165), Expect = 5e-11
Identities = 76/280 (27%), Positives = 118/280 (42%), Gaps = 42/280 (15%)
Query: 938 WVWDQEE--ERKRQE-------RWQKEQDRLLQEKYQREQEKLREEW---QRAKQEAERE 985
W W EE ER RQ R Q+E+ +E+ QREQ L EE QR +Q ERE
Sbjct: 769 WQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQREQRFLPEEEEKEQRRRQRRERE 828
Query: 986 NS-KYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEV 1044
++L+EE L RE + E E D+E R+ E+ R Q
Sbjct: 829 KELQFLEEE--------EQLQRRERAQQLQE---EEDGLQEDQERRRSQEQRRDQKWRWQ 877
Query: 1045 VHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSV 1104
+ E++ ++ + + ++QL++EQ+ LQ E EE +R E++R+ E ER
Sbjct: 878 LEEERKRRRH---TLYAKPALQEQLRKEQQL--LQEEEEELQREEREKRRRQEQER---- 928
Query: 1105 RIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTS 1164
QYR + ++ L +R K R Y +K K +G
Sbjct: 929 ---QYREE------EQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPE 979
Query: 1165 SQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQ 1204
+RR ++E+ E +Q+ Q +R+ W RQ
Sbjct: 980 KRRRQEREKKYREEEELQQEEEQLLREEREKRRRQEWERQ 1019
Score = 67.0 bits (162), Expect = 1e-10
Identities = 64/278 (23%), Positives = 120/278 (43%), Gaps = 24/278 (8%)
Query: 939 VWDQEEE---RKRQERWQKEQDRLLQEKYQREQEKLREEWQRAK---QEAERENSKYLDE 992
V+ +EEE RKR+ +KE+++L +E+ QR++E EE Q K QE RE + +
Sbjct: 237 VFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLERQELRRERQEEEQQ 296
Query: 993 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGE-----EERRQPQEEVVHE 1047
+ + + E E + + +E R + EERR+ Q E
Sbjct: 297 QQRLRREQQLRRKQEEERREQQEERREQQERREQQEERREQQLRREQEERREQQLRREQE 356
Query: 1048 DQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIY 1107
++ ++ Q + E ER+ +Q +E+Q ++ Q E+Q R ++ +R+ ++ RE +R
Sbjct: 357 EERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 416
Query: 1108 QYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELD--------DYSTNKNGNNKYLDQI 1159
Q R + EE +R + R E + + T ++ + Q+
Sbjct: 417 QQLRREQQLRREQEEERHEQKHEQERREQRLKREQEERRDWLKREEETERHEQERRKQQL 476
Query: 1160 GNMTSSQRRSK-----KEQVPSGAELERQQILQEMRKR 1192
+RR + +E+ E QQ+ +E +R
Sbjct: 477 KRDQEEERRERWLKLEEEERREQQERREQQLRREQEER 514
Score = 65.1 bits (157), Expect = 5e-10
Identities = 70/286 (24%), Positives = 127/286 (44%), Gaps = 42/286 (14%)
Query: 943 EEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSM 1002
E + +++E Q+E+++LL+E+ ++ + + RE R ++E ++E + L EE +
Sbjct: 1077 ERQYRKEEELQQEEEQLLREEPEKRRRQERERQCREEEELQQEEEQLLREEREKRRRQEL 1136
Query: 1003 SLTTREPSLATWEATW-----SEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQL 1057
RE E E + + E EEE +Q +E+++ E+Q K+ Q
Sbjct: 1137 ERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQ--- 1193
Query: 1058 VIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVR---IY------- 1107
ERER++ ++ +E Q QKR Q +E +R + K Q E E+E +VR +Y
Sbjct: 1194 --ERERQYREE-EELQRQKRKQRYRDEDQR--SDLKWQWEPEKENAVRDNKVYCKGRENE 1248
Query: 1108 QYRRPVDSYDIPKTEEASSGFLPG-----DRNKSR-------------STTELDDYSTNK 1149
Q+R+ DS + + L G DR + R E ++ K
Sbjct: 1249 QFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAK 1308
Query: 1150 NGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPL 1195
+ K ++ + + ++ Q E +Q+LQE R+ PL
Sbjct: 1309 RRDRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQE-REEQPL 1353
Score = 62.8 bits (151), Expect = 2e-09
Identities = 50/189 (26%), Positives = 96/189 (50%), Gaps = 26/189 (13%)
Query: 942 QEEERKRQER-WQKEQDRLLQEK---YQREQEKLREEWQRAKQEAERENSKYLDEELMVL 997
Q++ R+RQ+R +Q+E+++ +++ ++E+EKL+EE + ++E + E +E+L L
Sbjct: 227 QQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEE-----EEQLRKL 281
Query: 998 SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQL 1057
+ +E + + E R +EERR+ QE E Q ++ + QL
Sbjct: 282 ERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQER--REQQEERREQQL 339
Query: 1058 VIERERKWEQQLQ--------------EEQEQKR-LQAEAEEQKRPAEEQKRQAEIERET 1102
E+E + EQQL+ E++E++R Q E+Q R ++ +R+ ++ RE
Sbjct: 340 RREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQQLRREQ 399
Query: 1103 SVRIYQYRR 1111
+R Q R
Sbjct: 400 QLRREQQLR 408
Score = 58.9 bits (141), Expect = 3e-08
Identities = 59/262 (22%), Positives = 125/262 (47%), Gaps = 22/262 (8%)
Query: 941 DQEEERKRQERWQK---EQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVL 997
++E + +RQER Q+ ++DR +E+ Q QE EE Q +QE +R+ + +E+ +
Sbjct: 1647 EEEPQLRRQEREQQLRHDRDRKFREEEQLLQEG--EEQQLRRQERDRKFRE--EEQQLRR 1702
Query: 998 SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQL 1057
E L E + R+ T + R++ +++ E+Q + +++
Sbjct: 1703 QERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQ 1762
Query: 1058 VI---ERERKW--EQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE--TSVRIYQYR 1110
+ ER+RK+ E+QL++E+E+++L+++ ++K EEQ RQ E++ R +YR
Sbjct: 1763 QLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYR 1822
Query: 1111 RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSK 1170
+ + + E+ + + R + ++T + + ++ +RR +
Sbjct: 1823 WEEEQLQLEEQEQRLR------QERDRQYRAEEQFATQEKSRREE-QELWQEEEQKRRQE 1875
Query: 1171 KEQVPSGAELERQQILQEMRKR 1192
+E+ + RQQ +E R R
Sbjct: 1876 RERKLREEHIRRQQ-KEEQRHR 1896
Score = 58.5 bits (140), Expect = 4e-08
Identities = 55/264 (20%), Positives = 120/264 (45%), Gaps = 19/264 (7%)
Query: 941 DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 1000
++E++ RQER +K ++ +E+ R QE+ R+ + +Q + + K+ +EE ++
Sbjct: 1418 EEEQQLSRQERDRKFRE---EEQQVRRQERERKFLEEEQQLRQERHRKFREEEQLLQERE 1474
Query: 1001 SMSLTTREPSLATWEATWSEGSKSSDR----EGTRAGEEERR-QPQEEVVHEDQGKKP-- 1053
L +E E + DR + R+ E ER+ +E+ +H Q ++
Sbjct: 1475 EQQLHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPERKFLEEEQQLHRQQRQRKFL 1534
Query: 1054 QDQLVIERERKWEQQLQEE----QEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQY 1109
Q++ + R+ + +Q+ Q+ +E+++L+ E EEQ+ +E+ R+ +E + R Q
Sbjct: 1535 QEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREEQQLSRQERDRKFRLEEQKVRRQEQE 1594
Query: 1110 RRPVDSYDIPKTEEASSGFLPGDRNKSRSTTEL-----DDYSTNKNGNNKYLDQIGNMTS 1164
R+ ++ + +E K R +L + + + K+L++ +
Sbjct: 1595 RKFMEDEQQLRRQEGQQQLRQERDRKFREDEQLLQEREEQQLHRQERDRKFLEEEPQLRR 1654
Query: 1165 SQRRSKKEQVPSGAELERQQILQE 1188
+R + E +Q+LQE
Sbjct: 1655 QEREQQLRHDRDRKFREEEQLLQE 1678
Score = 57.4 bits (137), Expect = 9e-08
Identities = 65/266 (24%), Positives = 119/266 (44%), Gaps = 29/266 (10%)
Query: 938 WVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVL 997
W+ +EE + ++ +K+Q + QE+ +RE+ EE +R +Q+ RE ++E
Sbjct: 457 WLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQLRREQE---- 512
Query: 998 SSNSMSLTTREPSLATWEATWSEGSKSSDREGTR----AGEEERRQPQEEVVHEDQGKKP 1053
L +E + SE ++E R EEE+R QE E + K+
Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQER--REQRLKRE 570
Query: 1054 Q----DQLVIERERKWEQQLQEEQEQKRLQ-AEAEEQKRPAEEQKRQAEIERETSVRIYQ 1108
Q DQL+ E + +Q+L+ EQE++ Q + EE +R +E++R+ ++RE +
Sbjct: 571 QEERRDQLLKREEERRQQRLKREQEERLEQRLKREEVERLEQEERREQRLKREEP---EE 627
Query: 1109 YRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRR 1168
RR + K+EE + R E + + + L+Q + R
Sbjct: 628 ERR----QQLLKSEEQEE---RRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEER 680
Query: 1169 SKKEQVPSGAELERQQILQEMRKRTP 1194
++E AE E++Q + ++ R P
Sbjct: 681 REQEL----AEEEQEQARERIKSRIP 702
Score = 56.2 bits (134), Expect = 2e-07
Identities = 59/286 (20%), Positives = 129/286 (45%), Gaps = 33/286 (11%)
Query: 940 WDQEE----ERKRQERWQKEQDRLLQEKYQREQEKLREEWQ--RAKQEAERENSKYLDEE 993
W Q + E ++ ER ++++ + K Q E++ LREE + R +QE +R K+ +EE
Sbjct: 1286 WQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREEREEKRRRQETDR---KFREEE 1342
Query: 994 LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEE----VVHEDQ 1049
++ L +E + + E +G + EEE+R ++E + E+Q
Sbjct: 1343 QLLQEREEQPLRRQER-----DRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQ 1397
Query: 1050 GKKPQD---QLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRI 1106
+ Q+ QL +R+RK+ ++ Q+ Q+R + EE+++ +++ + +E E +R
Sbjct: 1398 QLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQ 1457
Query: 1107 YQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQ 1166
++R+ + + + E + + R E + + + K+ +Q +
Sbjct: 1458 ERHRKFREEEQLLQEREEQQ---LHRQERDRKFLEEEQQLRRQERDRKFREQELRSQEPE 1514
Query: 1167 RRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1212
R+ +E+ QQ+ ++ R+R L + RQ ++
Sbjct: 1515 RKFLEEE---------QQLHRQQRQRKFLQEEQQLRRQERGQQRRQ 1551
Score = 56.2 bits (134), Expect = 2e-07
Identities = 60/271 (22%), Positives = 122/271 (45%), Gaps = 37/271 (13%)
Query: 935 PSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEEL 994
P R ++E++ RQ+R Q K+ +E+++LR + +R +Q + + K+ +EE
Sbjct: 1513 PERKFLEEEQQLHRQQR---------QRKFLQEEQQLRRQ-ERGQQRRQDRDRKFREEEQ 1562
Query: 995 MVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ----G 1050
+ L+ +E DR+ ++ RRQ QE ED+
Sbjct: 1563 LRQEREEQQLSRQE----------------RDRKFRLEEQKVRRQEQERKFMEDEQQLRR 1606
Query: 1051 KKPQDQLVIERERKW--EQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQ 1108
++ Q QL ER+RK+ ++QL +E+E+++L + E ++ EE+ + ERE +R +
Sbjct: 1607 QEGQQQLRQERDRKFREDEQLLQEREEQQLHRQ-ERDRKFLEEEPQLRRQEREQQLRHDR 1665
Query: 1109 YRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQ-R 1167
R+ + + + E + + R E + + K+L + + +
Sbjct: 1666 DRKFREEEQLLQEGEEQQ---LRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELE 1722
Query: 1168 RSKKEQVPSGAELERQQILQEMRKRTPLHND 1198
R +E+ E E++Q+ ++ R R L +
Sbjct: 1723 RKFREEEQLRQETEQEQLRRQERYRKILEEE 1753
Score = 55.8 bits (133), Expect = 3e-07
Identities = 62/280 (22%), Positives = 115/280 (41%), Gaps = 43/280 (15%)
Query: 941 DQEEERKRQERWQKEQDRLLQEKY-------------------QREQEKLREEWQRAKQE 981
D+E R+RQE WQ+ ++R +E+ +RE +LR + + KQ+
Sbjct: 170 DEELWRQRQE-WQEREERRAEEEQLQSCKGHETEEFPDEEQLRRRELLELRRKGREEKQQ 228
Query: 982 AERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQ 1041
RE + +E RE L E E RE E+ R+ +
Sbjct: 229 QRRERQDRVFQE-----EEEKEWRKRETVLRKEEEKLQEEEPQRQRELQEEEEQLRKLER 283
Query: 1042 EEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1101
+E+ E Q ++ Q Q + ++ +Q +E +EQ +E++R +E++ Q E RE
Sbjct: 284 QELRRERQEEEQQQQRLRREQQLRRKQEEERREQ-------QEERREQQERREQQEERRE 336
Query: 1102 TSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGN 1161
+R Q R + EE L ++ + R +L + L +
Sbjct: 337 QQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQL--------RREQQLRREQQ 388
Query: 1162 MTSSQRRSKKEQVPSGAELERQQIL---QEMRKRTPLHND 1198
+ Q+ +++Q+ +L R+Q L Q++R+ L +
Sbjct: 389 LRREQQLRREQQLRREQQLRREQQLRREQQLRREQQLRRE 428
Score = 55.8 bits (133), Expect = 3e-07
Identities = 60/300 (20%), Positives = 124/300 (41%), Gaps = 48/300 (16%)
Query: 941 DQEEERKRQERWQKEQDRLLQEKYQREQEKLRE-------EWQRAKQEAERENSKYLDEE 993
+ EEER++Q +EQ+ Q++ +REQ++ RE E +R +Q +RE+ + E+
Sbjct: 624 EPEEERRQQLLKSEEQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREHEEERREQ 683
Query: 994 LMVLSSNSMSLTTREPSLATWE------------ATWSEGSKSSDREGTRAGEEERRQPQ 1041
+ + + + W+ +S K + + EE+RR+ +
Sbjct: 684 ELAEEEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRE 743
Query: 1042 EEV--VHEDQGKKPQDQLVIERERKWEQQLQE----------------EQEQKRLQAEAE 1083
E+ E++ + Q + R+ W+ Q +E EQ +++L+AE
Sbjct: 744 SELQWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEER 803
Query: 1084 EQKR----PAE---EQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKS 1136
+Q+ P E EQ+R+ ERE ++ + + + + + L D+ +
Sbjct: 804 QQREQRFLPEEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERR 863
Query: 1137 RSTTELDD----YSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKR 1192
RS + D + + + ++ K++Q+ E E Q+ +E R+R
Sbjct: 864 RSQEQRRDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRR 923
Score = 55.8 bits (133), Expect = 3e-07
Identities = 68/290 (23%), Positives = 131/290 (45%), Gaps = 33/290 (11%)
Query: 939 VWDQEEERKRQE---RWQKEQDRLLQEK---YQREQEKLREEWQRAKQEAERENSKYLDE 992
V +EE+ R+E R ++E +R +E+ Q E++ LREE ++ +QE ER+ + +E
Sbjct: 1146 VQQEEEQLLREEPEKRRRQELERQYREEEELQQEEEQLLREEQEKRRQERERQYRE--EE 1203
Query: 993 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREG---TRAGEEER-RQPQEEVVHED 1048
EL + S W+ W +++ R+ + E E+ RQ ++ + +
Sbjct: 1204 ELQRQKRKQRYRDEDQRSDLKWQ--WEPEKENAVRDNKVYCKGRENEQFRQLEDSQLRDR 1261
Query: 1049 QGKKPQDQLVIERE--------RKWEQQ----LQEEQEQKRLQAEAEEQKRPAEEQKRQA 1096
Q ++ L+ E++ R+W+Q+ +EEQ ++ Q EA+ + R ++E+K+
Sbjct: 1262 QSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLL 1321
Query: 1097 EIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYL 1156
ERE R + R + E +R++ EL ++ K+L
Sbjct: 1322 REEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEEL----RHQEQGRKFL 1377
Query: 1157 DQIGNMTSSQRRSK--KEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQ 1204
++ + +R K KE+ + ER+Q L++ R R + RQ
Sbjct: 1378 EEEQRLRRQERERKFLKEEQQLRCQ-EREQQLRQDRDRKFREEEQQLSRQ 1426
Score = 54.7 bits (130), Expect = 6e-07
Identities = 63/292 (21%), Positives = 121/292 (41%), Gaps = 32/292 (10%)
Query: 941 DQEEERKRQERWQKEQDRLLQEK----YQREQEK--LREEWQRAKQEAERENSKYLD--E 992
+QE+ R+ +ER +E++ L ++K Y+ E ++ L+ +W+ K+ A R+N Y E
Sbjct: 1187 EQEKRRQERERQYREEEELQRQKRKQRYRDEDQRSDLKWQWEPEKENAVRDNKVYCKGRE 1246
Query: 993 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1052
L R+ + + ++E R + +R P+EE + ++ K+
Sbjct: 1247 NEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDREQERRRWQQRDRHFPEEEQLEREEQKE 1306
Query: 1053 PQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEE------QKRQAEIERETSVRI 1106
+ R+RK QE+K+L E E+KR +E ++ Q ERE
Sbjct: 1307 AK-----RRDRK-------SQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLR 1354
Query: 1107 YQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQ 1166
Q R + + +E FL ++ R E + + +Q +
Sbjct: 1355 RQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQLRQDRDR 1414
Query: 1167 RRSKKEQVPSGAELER------QQILQEMRKRTPLHNDNSWIRQRSASVNKE 1212
+ ++EQ S E +R QQ+ ++ R+R L + ++R +E
Sbjct: 1415 KFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREE 1466
Score = 53.9 bits (128), Expect = 1e-06
Identities = 36/159 (22%), Positives = 77/159 (48%), Gaps = 5/159 (3%)
Query: 943 EEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSM 1002
EEE+ R ER +++ R +++ RE+E+LR+E + + ++ + K+ +EE +
Sbjct: 1751 EEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLRSQESDRKFREEEQLRQEREEQ 1810
Query: 1003 SLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERE 1062
L P + W E + + R +E RQ + E Q K +++ + +E
Sbjct: 1811 QL---RPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQE 1867
Query: 1063 RKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1101
EQ+ ++E+E+K + Q++ + ++ EI+ +
Sbjct: 1868 E--EQKRRQERERKLREEHIRRQQKEEQRHRQVGEIKSQ 1904
Score = 52.0 bits (123), Expect = 4e-06
Identities = 42/171 (24%), Positives = 88/171 (51%), Gaps = 16/171 (9%)
Query: 942 QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERE-----NSKYLDEELMV 996
+E+E+ QER +++ R +R+++ L EE Q +QE E++ + K+ +EE ++
Sbjct: 1622 REDEQLLQEREEQQLHR-----QERDRKFLEEEPQLRRQEREQQLRHDRDRKFREEEQLL 1676
Query: 997 LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE-EVVHEDQGKKPQD 1055
L +E E + +R+ + ++ RRQ E + E+Q ++ +
Sbjct: 1677 QEGEEQQLRRQERDRKFREEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETE 1736
Query: 1056 QLVIERERKW-----EQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1101
Q + R+ ++ E+QL+ E+E+++L+ + ++K EEQ RQ E++
Sbjct: 1737 QEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787
Score = 47.0 bits (110), Expect = 1e-04
Identities = 43/204 (21%), Positives = 92/204 (45%), Gaps = 29/204 (14%)
Query: 381 EADLKRWEAIREASRLRHKKRLM----VERLFQKIYGENGSKSMSDVSAEDVQNLRQLRY 436
E + +R + +R + R ++RL ERL Q++ E+ E+ + ++L
Sbjct: 638 EQEERRQQQLRREQQERREQRLKREEEEERLEQRLKREH----------EEERREQELAE 687
Query: 437 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 496
EE ++ + ++K + KWQ L D R+S +K+E + ++Q ++ +R S+
Sbjct: 688 EEQEQARERIKSRIPKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESEL- 746
Query: 497 KEMLQDRESQNQKSTVPSRRRMYSFDDVLEE---------GKRPPTMTVSEASYQSERVE 547
Q+ E +++ +RR +++ EE RPP E ++E +
Sbjct: 747 --QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQ 804
Query: 548 EKGATYPSEIPKEDSTTFAKREDR 571
++ + +P+E+ +R+ R
Sbjct: 805 QREQRF---LPEEEEKEQRRRQRR 825
Score = 45.4 bits (106), Expect = 4e-04
Identities = 44/226 (19%), Positives = 97/226 (42%), Gaps = 14/226 (6%)
Query: 380 SEADLKRWEAIREASRLRHK--KRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYE 437
SE L+R + R L+ + KRL ER Q++ E + + E+ + ++L+ E
Sbjct: 534 SEQQLRREQEERREQLLKREEEKRLEQERREQRLKREQEERRDQLLKREEERRQQRLKRE 593
Query: 438 EMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFK 497
+ ++++ +LK ++ + + ++RR+ + ++E R+++ K ++ +R + +
Sbjct: 594 QEERLEQRLKREEVERLEQ----EERREQRLKREEPEEERRQQLLKSEEQEERRQQQLRR 649
Query: 498 EMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEI 557
E Q+R Q K R EE +R + E ER++ S I
Sbjct: 650 EQ-QERREQRLKREEEEERLEQRLKREHEEERREQELAEEEQEQARERIK-------SRI 701
Query: 558 PKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQME 603
PK ++ + R + P + + + R R ++++
Sbjct: 702 PKWQWQLESEADARQSKVYSRPRKQEGQRRRQEQEEKRRRRESELQ 747
Score = 45.4 bits (106), Expect = 4e-04
Identities = 39/191 (20%), Positives = 86/191 (45%), Gaps = 11/191 (5%)
Query: 896 ESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKE 955
E + + + L+R+ ++ + + + P+ + R +EEE+ RQER +++
Sbjct: 1728 EEQLRQETEQEQLRRQERYRKILEEEQLRPEREEQQLRRQERDRKFREEEQLRQEREEQQ 1787
Query: 956 QDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWE 1015
++ RE+E+LR+E + + ++ + KY EE + L +E L
Sbjct: 1788 LRSQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEE------EQLQLEEQEQRLRQ-- 1839
Query: 1016 ATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQ 1075
+ E E+ RR+ QE E+Q ++ + + + E QQ +E++ +
Sbjct: 1840 ---ERDRQYRAEEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHR 1896
Query: 1076 KRLQAEAEEQK 1086
+ + +++E K
Sbjct: 1897 QVGEIKSQEGK 1907
Score = 44.7 bits (104), Expect = 6e-04
Identities = 52/280 (18%), Positives = 111/280 (39%), Gaps = 30/280 (10%)
Query: 335 KEKSNSCRILVPSYRQKKDDMLTRKIQSWKLGTTVPPISFTPGPC---------SEADLK 385
+E+S L RQ++D+ L R+ Q W+ C E L+
Sbjct: 152 EEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDEEQLR 211
Query: 386 RWEAIREASRLRHKKRLMVERLFQKIYGENGSKSM-----------SDVSAEDVQNLRQL 434
R E + + R +K+ +++ E K + E+ Q R+L
Sbjct: 212 RRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQRQREL 271
Query: 435 RYE-------EMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALE 487
+ E E Q+++ + +E++Q+ Q + + RRK ++++E RE+ E++ +
Sbjct: 272 QEEEEQLRKLERQELRRERQEEEQQQQRLRREQQLRRKQEEERREQQEERREQQERREQQ 331
Query: 488 KSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVE 547
+ +R + +E + RE Q ++ RR + EE + + + +
Sbjct: 332 EERREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRR 391
Query: 548 EKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQ 587
E+ ++ +E +RE ++ E QL + + +
Sbjct: 392 EQQLRREQQLRREQQ---LRREQQLRREQQLRREQQLRRE 428
Score = 43.1 bits (100), Expect = 0.002
Identities = 50/238 (21%), Positives = 92/238 (38%), Gaps = 25/238 (10%)
Query: 392 EASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQ 451
E ++R ER + + E + A+ +Q E+ ++ +SQ + +DQ
Sbjct: 813 EEEEKEQRRRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQERRRSQEQRRDQ 872
Query: 452 KWQDDLAKWKDRRK-----------SYTSDLQKKKEEREEIEKQALEKSKRSSK----TF 496
KW+ L + + RR+ + Q +EE EE++++ EK +R +
Sbjct: 873 KWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQREEREKRRRQEQERQYRE 932
Query: 497 KEMLQDRESQ-----NQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGA 551
+E LQ E Q +K R R Y D L++ + E + ER EK
Sbjct: 933 EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQER--EKKY 990
Query: 552 TYPSEIPKEDSTTFAKRED---RVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTR 606
E+ +E+ + + R E Q + ++++ L R + E R
Sbjct: 991 REEEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERER 1048
Score = 42.0 bits (97), Expect = 0.004
Identities = 49/242 (20%), Positives = 105/242 (43%), Gaps = 27/242 (11%)
Query: 391 REASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQL-KEQ 449
R+ +++K +++ +++ GE K + + +L+ EE Q ++ + K +
Sbjct: 953 RQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYREEEELQQEEEQLLREEREKRR 1012
Query: 450 DQKWQDDLAKWKDRRKSYTSDLQKKKEE--REEIEKQALEKSKRSSKTFKEMLQDRESQN 507
Q+W+ K KD +LQ+++E+ REE EK+ L++ +R + +E+ Q+ E
Sbjct: 1013 RQEWERQYRK-KD-------ELQQEEEQLLREEREKRRLQERERQYREEEELQQEEEQLL 1064
Query: 508 QKSTVPSRR----RMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDST 563
+ RR R Y ++ L++ + E + ER E+ E+ +E+
Sbjct: 1065 GEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQER--ERQCREEEELQQEEEQ 1122
Query: 564 TFAKRED---RVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDT 620
+ + R E Q + V+++ L + + E L R YR+ +
Sbjct: 1123 LLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQE-------LERQYREEEE 1175
Query: 621 VR 622
++
Sbjct: 1176 LQ 1177
Score = 39.7 bits (91), Expect = 0.020
Identities = 44/237 (18%), Positives = 93/237 (39%), Gaps = 15/237 (6%)
Query: 391 REASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQD 450
R +LR ++ E+ ++ E + E+ + +QLR E+ + + QL+ +
Sbjct: 334 RREQQLRREQEERREQQLRREQEEERREQQLRREQEEERREQQLRREQQLRREQQLRREQ 393
Query: 451 QKWQDDLAKWKD---------RRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQ 501
Q ++ + + R + + Q ++E+ EE +Q E+ +R + +E +
Sbjct: 394 QLRREQQLRREQQLRREQQLRREQQLRREQQLRREQEEERHEQKHEQERREQRLKREQEE 453
Query: 502 -----DRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSE 556
RE + ++ R++ D E +R + E Q ER E++ E
Sbjct: 454 RRDWLKREEETERHEQERRKQQLKRDQEEERRERWLKLEEEERREQQERREQQ-LRREQE 512
Query: 557 IPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPR 613
+E + E+R+ ++ Q E++ R ++E R L R
Sbjct: 513 ERREQRLKRQEEEERLQQRLRSEQQLRREQEERREQLLKREEEKRLEQERREQRLKR 569
Score = 38.5 bits (88), Expect = 0.045
Identities = 43/216 (19%), Positives = 96/216 (44%), Gaps = 27/216 (12%)
Query: 391 REASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQD 450
RE RH++ ++L ++ E + + E+ + ++ R +++++ + + +EQ
Sbjct: 460 REEETERHEQERRKQQL-KRDQEEERRERWLKLEEEERREQQERREQQLRREQEERREQR 518
Query: 451 QKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKS 510
K Q++ + + R +S ++++E RE++ K+ E+ KR + +E RE + ++
Sbjct: 519 LKRQEEEERLQQRLRSEQQLRREQEERREQLLKR--EEEKRLEQERREQRLKREQEERRD 576
Query: 511 TVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKRED 570
+ R EE +R + Q ER+E++ + +E+ + E
Sbjct: 577 QLLKR----------EEERRQQRL----KREQEERLEQR-------LKREEVERLEQEER 615
Query: 571 RVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTR 606
R E +L + P EE+ L S + + R
Sbjct: 616 R---EQRLKREEPEEERRQQLLKSEEQEERRQQQLR 648
Score = 37.7 bits (86), Expect = 0.077
Identities = 33/129 (25%), Positives = 65/129 (50%), Gaps = 13/129 (10%)
Query: 391 REASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQ- 449
RE LR ++R R + + E G K + + Q + +E Q+++ Q +EQ
Sbjct: 1348 REEQPLRRQERDRKFREEELRHQEQGRKFLEEEQRLRRQERERKFLKEEQQLRCQEREQQ 1407
Query: 450 -----DQKWQDD---LAKWKDRRKSYTSDLQKKKEERE----EIEKQALEKSKRSSKTFK 497
D+K++++ L++ + RK + Q +++ERE E E+Q ++ R + +
Sbjct: 1408 LRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQERERKFLEEEQQLRQERHRKFREEE 1467
Query: 498 EMLQDRESQ 506
++LQ+RE Q
Sbjct: 1468 QLLQEREEQ 1476
Score = 37.0 bits (84), Expect = 0.13
Identities = 37/169 (21%), Positives = 77/169 (45%), Gaps = 15/169 (8%)
Query: 381 EADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQ 440
E L+R E ++ R +K E+L Q+ E+ Q RQ R + +
Sbjct: 1649 EPQLRRQEREQQLRHDRDRKFREEEQLLQE--------------GEEQQLRRQERDRKFR 1694
Query: 441 KIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEML 500
+ + QL+ Q+++ + + + RR+ +++++ R+E E++ L + +R K +E
Sbjct: 1695 EEEQQLRRQERERKFLQEEQQLRRQELERKFREEEQLRQETEQEQLRRQERYRKILEEEQ 1754
Query: 501 QDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 549
E + Q+ R R + ++ L + +R S+ S + R EE+
Sbjct: 1755 LRPEREEQQLRRQERDRKFREEEQLRQ-EREEQQLRSQESDRKFREEEQ 1802
Score = 35.0 bits (79), Expect = 0.50
Identities = 20/78 (25%), Positives = 45/78 (57%), Gaps = 4/78 (5%)
Query: 1023 KSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQA-- 1080
K ++E A EE+ + QE + D+ ++ D+ + + ++W+++ + E+++LQ+
Sbjct: 140 KRQEQERELAEGEEQSEKQERLEQRDRQRR--DEELWRQRQEWQEREERRAEEEQLQSCK 197
Query: 1081 EAEEQKRPAEEQKRQAEI 1098
E ++ P EEQ R+ E+
Sbjct: 198 GHETEEFPDEEQLRRREL 215
Score = 35.0 bits (79), Expect = 0.50
Identities = 22/97 (22%), Positives = 51/97 (52%), Gaps = 3/97 (3%)
Query: 437 EEMQKIKSQL--KEQDQKWQDDLAK-WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 493
EE+Q+ + QL +E++++ + +L + +++ + + Q +EE E+ +Q LE+ R
Sbjct: 1114 EELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQELERQYREE 1173
Query: 494 KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKR 530
+ ++ + + Q+ R R Y ++ L+ KR
Sbjct: 1174 EELQQEEEQLLREEQEKRRQERERQYREEEELQRQKR 1210
Score = 35.0 bits (79), Expect = 0.50
Identities = 35/134 (26%), Positives = 69/134 (51%), Gaps = 12/134 (8%)
Query: 382 ADLK-RWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNL---RQLRYE 437
+DLK +WE +E + +R K R ++ S+ S +D+Q+L +Q R
Sbjct: 1221 SDLKWQWEPEKE-NAVRDNKVYCKGRENEQFRQLEDSQLRDRQSQQDLQHLLGEQQERDR 1279
Query: 438 EMQKIKSQLK-----EQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRS 492
E ++ + Q + E++Q +++ + K R + + Q +EERE EK+ +++ R
Sbjct: 1280 EQERRRWQQRDRHFPEEEQLEREEQKEAKRRDRKSQEEKQLLREERE--EKRRRQETDRK 1337
Query: 493 SKTFKEMLQDRESQ 506
+ +++LQ+RE Q
Sbjct: 1338 FREEEQLLQEREEQ 1351
Score = 35.0 bits (79), Expect = 0.50
Identities = 28/153 (18%), Positives = 72/153 (47%), Gaps = 13/153 (8%)
Query: 426 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQA 485
ED Q + +++Q + + +E+D+ + + +W+ R + + + Q ++EE++E +++
Sbjct: 1254 EDSQLRDRQSQQDLQHLLGEQQERDR--EQERRRWQQRDRHFPEEEQLEREEQKEAKRR- 1310
Query: 486 LEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSE- 544
R S+ K++L++ + ++ R+ + E ++P + ++ E
Sbjct: 1311 ----DRKSQEEKQLLREEREEKRRRQETDRKFREEEQLLQEREEQPLRRQERDRKFREEE 1366
Query: 545 -RVEEKGATYPSEIPK----EDSTTFAKREDRV 572
R +E+G + E + E F K E ++
Sbjct: 1367 LRHQEQGRKFLEEEQRLRRQERERKFLKEEQQL 1399
Score = 35.0 bits (79), Expect = 0.50
Identities = 46/235 (19%), Positives = 100/235 (42%), Gaps = 16/235 (6%)
Query: 392 EASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQ 451
E +LR ++R +R F++ E + + +Q +QLR +E+++ + +E++Q
Sbjct: 1680 EEQQLRRQER---DRKFRE---EEQQLRRQERERKFLQEEQQLRRQELER---KFREEEQ 1730
Query: 452 KWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKE--MLQDRESQNQK 509
Q+ + R++ Y L+++ + R E E+Q L + +R K +E + Q+RE Q +
Sbjct: 1731 LRQETEQEQLRRQERYRKILEEE-QLRPEREEQQLRRQERDRKFREEEQLRQEREEQQLR 1789
Query: 510 STVPSR--RRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAK 567
S R R EE + P + ++ E+++ + + +E +
Sbjct: 1790 SQESDRKFREEEQLRQEREEQQLRPQQRDGKYRWEEEQLQLE--EQEQRLRQERDRQYRA 1847
Query: 568 REDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVR 622
E T E + + ++ R R + E R + +R+ ++
Sbjct: 1848 EEQFATQEKSRREEQELWQEEEQKRRQERERKLREEHIRRQQKEEQRHRQVGEIK 1902
Score = 35.0 bits (79), Expect = 0.50
Identities = 32/140 (22%), Positives = 68/140 (48%), Gaps = 21/140 (15%)
Query: 381 EADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQ 440
E L+R E R + R +++L ER Q++ + SD + + LRQ R E Q
Sbjct: 1761 EQQLRRQERDR---KFREEEQLRQEREEQQLRSQE-----SDRKFREEEQLRQEREE--Q 1810
Query: 441 KIKSQLKEQDQKWQDDLAKWKD--------RRKSYTSDLQKKKEEREEIEKQAL---EKS 489
+++ Q ++ +W+++ + ++ R + Y ++ Q +E+ E+Q L E+
Sbjct: 1811 QLRPQQRDGKYRWEEEQLQLEEQEQRLRQERDRQYRAEEQFATQEKSRREEQELWQEEEQ 1870
Query: 490 KRSSKTFKEMLQDRESQNQK 509
KR + +++ ++ + QK
Sbjct: 1871 KRRQERERKLREEHIRRQQK 1890
Score = 34.7 bits (78), Expect = 0.65
Identities = 28/138 (20%), Positives = 63/138 (45%), Gaps = 14/138 (10%)
Query: 426 EDVQNLRQLRYEEMQKIKSQLKEQDQKW-------------QDDLAKWKDRRKSYTSDLQ 472
E+ Q LRQ R+ + ++ + L+E++++ + L + + RK +L+
Sbjct: 1450 EEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLRRQERDRKFREQELR 1509
Query: 473 KKKEEREEIEK-QALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRP 531
++ ER+ +E+ Q L + +R K +E Q R + + R R + ++ L + +
Sbjct: 1510 SQEPERKFLEEEQQLHRQQRQRKFLQEEQQLRRQERGQQRRQDRDRKFREEEQLRQEREE 1569
Query: 532 PTMTVSEASYQSERVEEK 549
++ E + E+K
Sbjct: 1570 QQLSRQERDRKFRLEEQK 1587
Score = 34.3 bits (77), Expect = 0.85
Identities = 39/216 (18%), Positives = 90/216 (41%), Gaps = 15/216 (6%)
Query: 1012 ATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQ- 1070
A +AT + K + +G + ++RRQ +++ E + ++ +++ R +K ++Q +
Sbjct: 88 ALGQATGLDEEKRARCDGKESLLQDRRQEEDQRRFEPRDRQLEEEPGQRRRQKRQEQERE 147
Query: 1071 ----EEQEQKRLQAEAEEQKRPAEE-----QKRQAEIERETSVRIYQYRRPVDSYDIPKT 1121
EEQ +K+ + E +++R EE Q+ Q ER Q + ++ + P
Sbjct: 148 LAEGEEQSEKQERLEQRDRQRRDEELWRQRQEWQEREERRAEEEQLQSCKGHETEEFPDE 207
Query: 1122 EEASSGFL-----PGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPS 1176
E+ L G K + E D + ++ + + + + ++E+
Sbjct: 208 EQLRRRELLELRRKGREEKQQQRRERQDRVFQEEEEKEWRKRETVLRKEEEKLQEEEPQR 267
Query: 1177 GAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1212
EL+ ++ +R L + Q+ + +E
Sbjct: 268 QRELQEEEEQLRKLERQELRRERQEEEQQQQRLRRE 303
Score = 34.3 bits (77), Expect = 0.85
Identities = 61/277 (22%), Positives = 114/277 (41%), Gaps = 40/277 (14%)
Query: 245 LRAFEDFRKF---------SEQDDSVERDIILQCREGELVLPDLEKD------DMIVRRI 289
LR E RKF E++ + +D + RE E L E+D + VRR
Sbjct: 1383 LRRQERERKFLKEEQQLRCQEREQQLRQDRDRKFREEEQQLSRQERDRKFREEEQQVRRQ 1442
Query: 290 PAQKKEVPLSGAPDRYHPVPFPEPWTLPPEIQAKFLCVLERTCPSKEKSNSCRILVPSYR 349
++K + + F E L E + + L ER E+ R R
Sbjct: 1443 ERERKFLEEEQQLRQERHRKFREEEQLLQEREEQQLHRQERDRKFLEEEQQLR------R 1496
Query: 350 QKKDDMLTRKIQSWKLGTTVPPISFTPGPCSEADLKRWEAIREASRLRHKKRLMVERLFQ 409
Q++D RK + +L + P F E L R + R +K L E+ +
Sbjct: 1497 QERD----RKFREQELRSQEPERKFLE---EEQQLHRQQ--------RQRKFLQEEQQLR 1541
Query: 410 KIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTS 469
+ + D + + LRQ R E Q++ Q +++ + ++ + +++ + +
Sbjct: 1542 RQERGQQRRQDRDRKFREEEQLRQEREE--QQLSRQERDRKFRLEEQKVRRQEQERKFME 1599
Query: 470 DLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQ 506
D Q+ + R+E ++Q ++ R + +++LQ+RE Q
Sbjct: 1600 DEQQLR--RQEGQQQLRQERDRKFREDEQLLQEREEQ 1634
Score = 33.9 bits (76), Expect = 1.1
Identities = 44/225 (19%), Positives = 94/225 (41%), Gaps = 17/225 (7%)
Query: 386 RWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDV---QNLRQLRYEEMQKI 442
+W+ A R + ++ + +Q E + +SA Q RQLR EE Q+
Sbjct: 747 QWQEEERAHRQQQEEEQRRDFTWQWQAEEKSERGRQRLSARPPLREQRERQLRAEERQQR 806
Query: 443 KSQ-LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQ 501
+ + L E+++K Q + +R+ +LQ +EE + ++ ++ + +E +
Sbjct: 807 EQRFLPEEEEKEQR-----RRQRREREKELQFLEEEEQLQRRERAQQLQEEEDGLQEDQE 861
Query: 502 DRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKED 561
R SQ Q+ R + + + E +R T+ A + R E++ E + +
Sbjct: 862 RRRSQEQR-----RDQKWRWQLEEERKRRRHTLYAKPALQEQLRKEQQLLQEEEEELQRE 916
Query: 562 STTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTR 606
+R+++ E Q + ++++ L R + + E R
Sbjct: 917 EREKRRRQEQ---ERQYREEEQLQQEEEQLLREEREKRRRQERER 958
Score = 33.9 bits (76), Expect = 1.1
Identities = 27/117 (23%), Positives = 60/117 (51%), Gaps = 12/117 (10%)
Query: 414 ENGSKSMSDVSAEDVQNLRQLRYEEM-QKIKSQLKEQDQKWQDDLAKWKD----RRKSYT 468
E + ++ E+ Q LR+ R + Q+++ Q +E+++ Q++ ++ RR+
Sbjct: 1107 ERQCREEEELQQEEEQLLREEREKRRRQELERQYREEEEVQQEEEQLLREEPEKRRRQEL 1166
Query: 469 SDLQKKKEEREEIEKQAL--EKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDD 523
+++EE ++ E+Q L E+ KR + ++ ++ E Q QK R++ Y +D
Sbjct: 1167 ERQYREEEELQQEEEQLLREEQEKRRQERERQYREEEELQRQK-----RKQRYRDED 1218
Score = 33.5 bits (75), Expect = 1.5
Identities = 52/275 (18%), Positives = 111/275 (40%), Gaps = 40/275 (14%)
Query: 386 RWEAIREASRLRHK---KRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKI 442
RW+ E R RH K + E+L ++ + + ++ E+ + R+ E +
Sbjct: 875 RWQLEEERKRRRHTLYAKPALQEQLRKE--QQLLQEEEEELQREEREKRRRQEQERQYRE 932
Query: 443 KSQLKEQDQKW---QDDLAKWKDRRKSYTSD--LQKKKEE----------REEIEKQALE 487
+ QL++++++ + + + ++R + Y D LQ+K+E+ R+E EK+ E
Sbjct: 933 EEQLQQEEEQLLREEREKRRRQERERQYRKDKKLQQKEEQLLGEEPEKRRRQEREKKYRE 992
Query: 488 KSKRSSKTFKEMLQDRESQNQKSTVPSRRR----MYSFDDVLEEGKRPPTMTVSEASY-- 541
+ + + + + ++RE + ++ R+ + +L E + + E Y
Sbjct: 993 EEELQQEEEQLLREEREKRRRQEWERQYRKKDELQQEEEQLLREEREKRRLQERERQYRE 1052
Query: 542 ----QSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVE------EQSPAS 591
Q E + G + +E + K E+ E QL + P + E+
Sbjct: 1053 EEELQQEEEQLLGEERETRRRQELERQYRKEEELQQEEEQLLREEPEKRRRQERERQCRE 1112
Query: 592 LSSLRSRSTQM----ESTRVSASLPRSYRKTDTVR 622
L+ Q+ R L R YR+ + V+
Sbjct: 1113 EEELQQEEEQLLREEREKRRRQELERQYREEEEVQ 1147
>gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 899
Score = 77.4 bits (189), Expect = 9e-14
Identities = 94/392 (23%), Positives = 166/392 (42%), Gaps = 59/392 (15%)
Query: 818 EWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEK---SSNLSVTTDFSES 874
E ++ + + H +++R A S K D E+ S L T +E
Sbjct: 163 ESKDLAGRLHHSWHFAGELQRALSAVSTRHKKADRYIEELTKERDALSLELYRNTITNEE 222
Query: 875 LQSSNIESKEINGIHDESNAFESKASE-SISLKNLKRRSQFFEQGSSDSVVPDLPVPTIS 933
L+ N E +E + ES+ SE +++K LKR+ + + ++P + T+
Sbjct: 223 LKKKNAELQE------KLPLAESEKSEIQLNVKELKRKLE-----RAKFLLPQVQTNTLQ 271
Query: 934 APSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAE---------R 984
+W QEEE + QE+ ++Q+ EK R++E+LRE+ + +++ E R
Sbjct: 272 EE---MWRQEEELREQEKKIRKQE----EKMWRQEERLREQEGKMREQEEKMWRQEKRLR 324
Query: 985 ENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEV 1044
E K L E+ L E E W + K ++E +EER QE+
Sbjct: 325 EQEKELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQ 384
Query: 1045 VHEDQGKKPQDQLVIERERKWEQ--QLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1102
+ E Q +K +DQ ER WEQ +L+E++E+ R Q + EQ E+K+ E E+
Sbjct: 385 MRE-QEQKMRDQ----EERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEK-- 437
Query: 1103 SVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNM 1162
KT + +R + R ++ T + K Q NM
Sbjct: 438 -----------------KTRDQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENM 480
Query: 1163 TSSQRRS-KKEQVPSGAE-LERQQILQEMRKR 1192
+ + +++++P E L Q+ +QE ++
Sbjct: 481 WEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEK 512
Score = 74.7 bits (182), Expect = 6e-13
Identities = 46/171 (26%), Positives = 90/171 (52%), Gaps = 4/171 (2%)
Query: 939 VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAE-RENSKYLDEELMVL 997
+W+QEE+ + QE+ +Q+ +++K Q +++K ++ ++ ++E RE K + EE ++
Sbjct: 546 MWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 605
Query: 998 SSNSMSLTTREPSLATWEAT-WSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQ 1056
+ +E + E W + K ++E +EE+ QEE + E Q Q +
Sbjct: 606 REQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKE 665
Query: 1057 LVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKR--QAEIERETSVR 1105
+ E E+ EQ+ +EQE+K + E E+K +E+K Q ++ E S+R
Sbjct: 666 KLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMR 716
Score = 70.1 bits (170), Expect = 1e-11
Identities = 47/173 (27%), Positives = 90/173 (52%), Gaps = 7/173 (4%)
Query: 939 VWDQEEERKRQER--WQKEQDRLLQEKYQREQEKLREEWQRA-KQEAERENSKYLDEELM 995
+W+QEE+ + QE W++E+ QE+ EQ++L E+ ++ + E +E K ++E
Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEK 685
Query: 996 VLSSNSMSLTTREPSLATWEAT-WSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK--K 1052
+ M T+E TW+ E +RE EEE + QEE + E + K +
Sbjct: 686 IWEQEKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQE 745
Query: 1053 PQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVR 1105
++++ + E+ WEQ+ ++ EQ+RL + E+ + Q+++ E+E +R
Sbjct: 746 QEEEMWEQEEKMWEQE-EKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMR 797
Score = 67.4 bits (163), Expect = 9e-11
Identities = 62/269 (23%), Positives = 125/269 (46%), Gaps = 23/269 (8%)
Query: 939 VWDQEEERKRQER-WQKEQD-RLLQEKYQREQEKLREEWQRAKQEA--ERENSKYLDEEL 994
+W+QE+ ++++E+ W++E+ R +E + +E++ R+E R +++ E+E E+
Sbjct: 500 LWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQK 559
Query: 995 MVLSSNSMSLTTREPSLATW--EATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1052
M M T+E TW E E + +RE EEE + QEE + E Q +K
Sbjct: 560 MWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQE-QEEK 618
Query: 1053 PQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP 1112
Q+Q E+ WEQ+ ++ QEQ+ E EE+ EE+ + + E +++++ +
Sbjct: 619 MQEQ----EEKMWEQE-EKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKM 673
Query: 1113 VDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKE 1172
+ + + EE ++ K T+ + T +++ S + R KK
Sbjct: 674 QEQEKMQEQEEKI-----WEQEKMEKKTQEQEKKTWDQ------EKMREEESMREREKKM 722
Query: 1173 QVPSGAELERQQILQEMRKRTPLHNDNSW 1201
+ E+++ +QE ++ + W
Sbjct: 723 REEEEMMREQEEKMQEQEEKMQEQEEEMW 751
Score = 65.5 bits (158), Expect = 3e-10
Identities = 67/287 (23%), Positives = 124/287 (43%), Gaps = 39/287 (13%)
Query: 939 VWDQEEERKRQERWQK-------EQDRLLQEKYQR--EQEKLREEWQRAKQEAERENSKY 989
+W+QE++ + QE+ + EQD L+EK +R EQEK+ E+ ++ ++E + + +
Sbjct: 378 LWEQEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEK 437
Query: 990 LDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ 1049
+ +E + E K + E T +EE+ Q QEE + E +
Sbjct: 438 KTRD-------------QEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQE 484
Query: 1050 GKKPQDQ-LVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQ 1108
K+ Q Q L ++E+ WEQ+ +EQE+K E EE+ R EE Q + ++++
Sbjct: 485 EKEWQQQRLPEQKEKLWEQEKMQEQEEKIW--EQEEKIRDQEEMWGQEK-------KMWR 535
Query: 1109 YRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQR- 1167
+ + D +E + K E + T + K DQ M +R
Sbjct: 536 QEKMREQEDQMWEQEEK---MRDQEQKMWDQEERMEKKTQEQ-EKKTWDQEEKMREEERM 591
Query: 1168 --RSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1212
R KK + E+++ +QE ++ + W ++ +E
Sbjct: 592 REREKKMREEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEE 638
Score = 62.8 bits (151), Expect = 2e-09
Identities = 47/182 (25%), Positives = 86/182 (47%), Gaps = 23/182 (12%)
Query: 940 WDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSS 999
WDQE+ R+ + ++E+ +E+ REQE+ +E + QE E E + EE M
Sbjct: 704 WDQEKMREEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEE--MWEQEEKMWEQE 761
Query: 1000 NSMSLTTREPS----------LATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ 1049
M R P + E W + K D+E G+EE+ + QEE + +
Sbjct: 762 EKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQE 821
Query: 1050 GKK--PQDQLVIERERKWEQQL----QEEQEQKRLQAEAE-----EQKRPAEEQKRQAEI 1098
K ++++ + E+ W Q+ QEE+ ++++Q + E E+K +E+K + +
Sbjct: 822 EKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQE 881
Query: 1099 ER 1100
E+
Sbjct: 882 EK 883
Score = 61.6 bits (148), Expect = 5e-09
Identities = 60/274 (21%), Positives = 117/274 (42%), Gaps = 31/274 (11%)
Query: 941 DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAER--ENSKYLDEELMVLS 998
++EE + QE+ ++ +++ +EK +EQEK + + QE ER E K + EE +
Sbjct: 408 EKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEETMR 467
Query: 999 SNSMSLTTREPSLATWEAT---WSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQD 1055
+ +E ++ WE W + +E + E+E+ Q QEE + E Q+
Sbjct: 468 EQEEKMQKQEENM--WEQEEKEWQQQRLPEQKE--KLWEQEKMQEQEEKIWE------QE 517
Query: 1056 QLVIERERKWEQQ----LQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRR 1111
+ + ++E W Q+ QE+ ++ Q +E+K +EQK + ER Q ++
Sbjct: 518 EKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKK 577
Query: 1112 PVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKK 1171
D + + EE R + R ++ + K +Q M Q + +K
Sbjct: 578 TWDQEEKMREEE---------RMREREKKMREEEEMMREQEEKMQEQEEKM---QEQEEK 625
Query: 1172 EQVPSGAELERQQILQEMRKRTPLHNDNSWIRQR 1205
E+++ + E ++ + W +QR
Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659
Score = 60.8 bits (146), Expect = 9e-09
Identities = 43/179 (24%), Positives = 87/179 (48%), Gaps = 23/179 (12%)
Query: 939 VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREE----WQRAKQE--AERENSKYLDE 992
+W+QEE+ Q+R +++++L + + +EQEK++E+ W++ K E + + K D+
Sbjct: 647 MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQ 706
Query: 993 ELMVLSSNSMSLTTREPSLATWEATWSEGS-KSSDREGTRAGEEERRQPQEEVVHEDQGK 1051
E M S+ RE + E E K ++E +EE QEE + E + K
Sbjct: 707 EKM---REEESMREREKKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEEKMWEQEEK 763
Query: 1052 KPQDQLVIER-------------ERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAE 1097
+ Q + E+ E+ WEQ+ + ++++++ + E+ + E+ + Q E
Sbjct: 764 MWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEKMRGQEE 822
Score = 57.0 bits (136), Expect = 1e-07
Identities = 60/302 (19%), Positives = 129/302 (42%), Gaps = 40/302 (13%)
Query: 942 QEEERKRQE----RWQKEQDRLLQEKYQREQEKLRE----EWQRAK-----------QEA 982
QEEER R+ R ++E R +EK Q+++E + E EWQ+ + ++
Sbjct: 447 QEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKM 506
Query: 983 ERENSKYLDEELMVLSSNSM-----SLTTREPSLATWEATWSEGSKSSDREGTRAGEEER 1037
+ + K ++E + M + +E + W + K D+E +EER
Sbjct: 507 QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEER 566
Query: 1038 ----RQPQEEVVHEDQGKKPQDQLVIERERKW--EQQLQEEQEQKRLQAEAEEQKRPAEE 1091
Q QE+ + + K +++ + ERE+K E+++ EQE+K +Q + E+ + E+
Sbjct: 567 MEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEK-MQEQEEKMQEQEEK 625
Query: 1092 QKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNG 1151
Q E +E ++++ + + E+ LP + K ++ + +
Sbjct: 626 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR---LPEQKEKLWEHEKMQEQEKMQEQ 682
Query: 1152 NNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKR-TPLHNDNSWIRQRSASVN 1210
K +Q + +EQ + E+ + + MR+R + + +R++ +
Sbjct: 683 EEKIWEQ-----EKMEKKTQEQEKKTWDQEKMREEESMREREKKMREEEEMMREQEEKMQ 737
Query: 1211 KE 1212
++
Sbjct: 738 EQ 739
Score = 55.8 bits (133), Expect = 3e-07
Identities = 38/144 (26%), Positives = 75/144 (52%), Gaps = 12/144 (8%)
Query: 939 VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLS 998
+W+QEE+ Q+R +++++L + + +EQEK+ E+ ++ + + E+ + EE M
Sbjct: 757 MWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEKMRGQ---EEKMRGQ 813
Query: 999 SNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHED-QGKKPQDQL 1057
M E W + K +E G+EE+ QEE + E QG++ + +
Sbjct: 814 EEKMR--------GQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEKMQGQEEKMRE 865
Query: 1058 VIERERKWEQQLQEEQEQKRLQAE 1081
E+ R E++++E++E+ R Q E
Sbjct: 866 QEEKMRGQEEKMREQEEKMRGQEE 889
Score = 41.2 bits (95), Expect = 0.007
Identities = 41/214 (19%), Positives = 95/214 (44%), Gaps = 26/214 (12%)
Query: 381 EADLKRW---EAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYE 437
E + K W E +RE R+R +++ M E +++ E K E +Q + +E
Sbjct: 573 EQEKKTWDQEEKMREEERMREREKKMREE--EEMMREQEEKMQEQ--EEKMQEQEEKMWE 628
Query: 438 EMQKIKSQ----------LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALE 487
+ +K++ Q + EQ++K + + + K + + +++E+ +E E++ E
Sbjct: 629 QEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKMQEQEEKIWE 688
Query: 488 KSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVE 547
+ K KT ++ + + + + R R E+ R + E + + E
Sbjct: 689 QEKMEKKTQEQEKKTWDQEKMREEESMRER--------EKKMREEEEMMREQEEKMQEQE 740
Query: 548 EKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQ 581
EK E+ +++ + ++E+++ + +LP Q
Sbjct: 741 EKMQEQEEEMWEQEEKMW-EQEEKMWEQQRLPEQ 773
Score = 39.3 bits (90), Expect = 0.027
Identities = 40/222 (18%), Positives = 98/222 (44%), Gaps = 24/222 (10%)
Query: 388 EAIREASRLRHK-KRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRY---------- 436
E ++E R+R + K++ E + E K ++ ++ + +Q R
Sbjct: 444 EKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQ 503
Query: 437 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER--------EEIEKQALEK 488
E+MQ+ + ++ EQ++K +D W +K + + +++E++ + E++ ++
Sbjct: 504 EKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQ 563
Query: 489 SKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVL---EEGKRPPTMTVSEASYQSER 545
+R K +E Q++++ +Q+ + RM + + EE R + E + +
Sbjct: 564 EERMEKKTQE--QEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMQE 621
Query: 546 VEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQ 587
EEK ++ +++ + + E E ++ Q + EQ
Sbjct: 622 QEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQ 663
Score = 38.5 bits (88), Expect = 0.045
Identities = 35/189 (18%), Positives = 86/189 (45%), Gaps = 10/189 (5%)
Query: 385 KRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKS 444
K W R+ RLR ++ M E+ + E + E + LR+ + E+++ +
Sbjct: 294 KMW---RQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQK--ELREQEE 348
Query: 445 QLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEML-QDR 503
Q++EQ++K + K +++ + + +++E E EKQ E+ ++ + M QD
Sbjct: 349 QMQEQEEKMWEQEEKMREQEEK----MWRQEERLWEQEKQMREQEQKMRDQEERMWEQDE 404
Query: 504 ESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDST 563
+ ++ + + +M+ + + E K+ + + EE+ + +E+
Sbjct: 405 RLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMREEEE 464
Query: 564 TFAKREDRV 572
T ++E+++
Sbjct: 465 TMREQEEKM 473
Score = 37.7 bits (86), Expect = 0.077
Identities = 28/169 (16%), Positives = 77/169 (45%), Gaps = 11/169 (6%)
Query: 381 EADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQ 440
E + K WE + K ERL+++ K M E Q +R + E M
Sbjct: 352 EQEEKMWEQEEKMREQEEKMWRQEERLWEQ------EKQMR----EQEQKMRD-QEERMW 400
Query: 441 KIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEML 500
+ +L+E++++ ++ W+ K +++E++ +++ +++ +R + K+M
Sbjct: 401 EQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQEEERIREREKKMR 460
Query: 501 QDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 549
++ E+ ++ ++ ++ +E ++ E ++ E+++E+
Sbjct: 461 EEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQ 509
Score = 35.4 bits (80), Expect = 0.38
Identities = 14/46 (30%), Positives = 32/46 (69%)
Query: 939 VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAER 984
+W QEE+ + + + Q+E+ R +EK + ++EK+RE+ ++ + + E+
Sbjct: 845 MWGQEEKMEEKMQGQEEKMREQEEKMRGQEEKMREQEEKMRGQEEK 890
Score = 35.0 bits (79), Expect = 0.50
Identities = 27/132 (20%), Positives = 65/132 (49%), Gaps = 6/132 (4%)
Query: 381 EADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQ 440
E + K WE + + + +++ ++ +K+ E + E+ + +R+ + E+MQ
Sbjct: 681 EQEEKIWEQEKMEKKTQEQEKKTWDQ--EKMREEESMREREKKMREEEEMMRE-QEEKMQ 737
Query: 441 KIKSQLKEQDQK-WQDDLAKWKDRRKSYTSD-LQKKKEEREEIEK-QALEKSKRSSKTFK 497
+ + +++EQ+++ W+ + W+ K + L ++KE+ E EK Q EK + +
Sbjct: 738 EQEEKMQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMR 797
Query: 498 EMLQDRESQNQK 509
+ + Q +K
Sbjct: 798 DQEEKMRGQEEK 809
Score = 34.7 bits (78), Expect = 0.65
Identities = 34/173 (19%), Positives = 76/173 (43%), Gaps = 19/173 (10%)
Query: 381 EADLKRW--EAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEE 438
E + K W E +RE +R +++ M E ++ E + +++ + E+
Sbjct: 698 EQEKKTWDQEKMREEESMREREKKMREE--------------EEMMREQEEKMQE-QEEK 742
Query: 439 MQKIKSQLKEQDQK-WQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFK 497
MQ+ + ++ EQ++K W+ + W+ +R + + E+ +E EK ++ K + K
Sbjct: 743 MQEQEEEMWEQEEKMWEQEEKMWEQQRLPEQKEKLWEHEKMQEQEKIWEQEEKMRDQEEK 802
Query: 498 EMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASY-QSERVEEK 549
Q+ + + Q+ + + + G+ E + Q E++EEK
Sbjct: 803 MRGQEEKMRGQEEKMRGQEEKMWGQEEKMWGQEEKMWGQEEKMWGQEEKMEEK 855
Score = 32.7 bits (73), Expect = 2.5
Identities = 21/117 (17%), Positives = 57/117 (48%), Gaps = 4/117 (3%)
Query: 437 EEMQKIKSQLKEQDQKWQDDLAK-WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKT 495
E+M + + +L+EQ+ K ++ K W+ ++ + + +++E+E E++ L + + +
Sbjct: 293 EKMWRQEERLREQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQE 352
Query: 496 FKEMLQDRES---QNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 549
+E + ++E + ++ R++ + + E ++ Q ER+ EK
Sbjct: 353 QEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREK 409
Score = 30.8 bits (68), Expect = 9.4
Identities = 25/114 (21%), Positives = 54/114 (47%), Gaps = 7/114 (6%)
Query: 401 RLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQK-WQDDLA- 458
+L V+ L +K+ E + V +Q + EE+++ + ++++Q++K W+ +
Sbjct: 245 QLNVKELKRKL--ERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIRKQEEKMWRQEERL 302
Query: 459 ---KWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQK 509
+ K R + Q+K+ +E E + EK R K +E + + Q +K
Sbjct: 303 REQEGKMREQEEKMWRQEKRLREQEKELREQEKELREQKELREQEEQMQEQEEK 356
>gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 750
Score = 75.5 bits (184), Expect = 3e-13
Identities = 66/321 (20%), Positives = 133/321 (41%), Gaps = 24/321 (7%)
Query: 939 VWDQEEERKRQERWQKEQDRLL--QEKYQREQEKLREEWQRAKQEAERENSKYLDEELMV 996
+W QEE+ + QE +EQ++ + QE+ EQEK+REE +R +QE + + E+ +
Sbjct: 432 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQEEI 491
Query: 997 LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQ 1056
E E W + K ++E +EE+ QEE + E + +++
Sbjct: 492 WRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIREQEEMWREEE 551
Query: 1057 LVIERERKWEQQLQEEQEQK------RLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYR 1110
+ E+E+ WE++ ++EQE K +++ + E+ R E+ + Q E +E ++++
Sbjct: 552 KMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQE 611
Query: 1111 RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNG--NNKYLDQIGNMTSSQ-- 1166
+ + E+ + K R E+ K G K +Q M +
Sbjct: 612 EKIREQEEKIQEQEEK--IREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEET 669
Query: 1167 --RRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGE 1224
R+ +K + E+++ ++E + + W ++ +E + E
Sbjct: 670 MWRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ--------E 721
Query: 1225 SLDNLDSPRSNSWRQPPWLNQ 1245
+ + W Q L Q
Sbjct: 722 QEEKMRRQEEKMWEQEVRLRQ 742
Score = 69.7 bits (169), Expect = 2e-11
Identities = 52/179 (29%), Positives = 90/179 (50%), Gaps = 14/179 (7%)
Query: 939 VWDQEEERKRQER--WQKEQDRLLQEKYQREQEKLRE-EWQRAKQEAERENSKYLDEELM 995
+W++EE+ +RQE W+KE+ E+ EQEK+RE E +R ++E RE K ++E
Sbjct: 372 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 431
Query: 996 VLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQD 1055
+ E + W + K ++E R EEE+RQ QEE+ Q+
Sbjct: 432 MWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIR--EEEKRQEQEEMWR-------QE 482
Query: 1056 QLVIERERKWEQ-QLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPV 1113
+ + E+E W Q + EQE+K ++ + E+ R E+ + Q E RE ++++ +
Sbjct: 483 EKIHEQEEIWRQKEKMHEQEEK-IRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKI 540
Score = 68.9 bits (167), Expect = 3e-11
Identities = 49/192 (25%), Positives = 101/192 (52%), Gaps = 14/192 (7%)
Query: 939 VWDQEEERKRQER-W-QKEQDRLLQEKYQREQEKLREEWQRAKQEAE---RENSKYLDEE 993
+W++E+ ++++++ W Q+E+ R +EK R++EK+RE+ ++ +++ E ++ K ++E
Sbjct: 559 IWEEEKRQEQEDKMWRQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEEKIREQE 618
Query: 994 LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-K 1052
+ E E T + K ++E +EE+ Q QEE + + K +
Sbjct: 619 EKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIR 678
Query: 1053 PQDQLVIERE---RKWEQQLQEEQ----EQKRLQAEAEEQKRPAEEQ-KRQAEIERETSV 1104
Q++ + E+E R+ E+ +QE++ EQ+ E EE+ + EE+ +RQ E E V
Sbjct: 679 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 738
Query: 1105 RIYQYRRPVDSY 1116
R+ Q + +
Sbjct: 739 RLRQQEEKMQEH 750
Score = 65.5 bits (158), Expect = 3e-10
Identities = 55/235 (23%), Positives = 116/235 (49%), Gaps = 20/235 (8%)
Query: 881 ESKEING-IHDESNAFESKASE-SISLKNLKRRSQFFE--------QGSSDSVVPDLPVP 930
E KE N + ++ ES+ SE +++K LKR+ + + Q +D + +L
Sbjct: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277
Query: 931 TISAPSRW----VWDQEEERKRQERW-QKEQDRLLQEKYQREQEKLREEWQRAKQEAE-- 983
+ ++ +W++ +++ ++ W Q+E+ + +EK Q ++EK+RE+ ++ +++ E
Sbjct: 278 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337
Query: 984 -RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE 1042
R+ ++E + M E E W + K +E +EE+ + E
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE 397
Query: 1043 EVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQK--RLQAEAEEQKRPAEEQKRQ 1095
E +HE + + Q++ E E+ EQ+ ++EQE K R + + EQ+ EQ+++
Sbjct: 398 EKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKK 452
Score = 56.2 bits (134), Expect = 2e-07
Identities = 44/162 (27%), Positives = 84/162 (51%), Gaps = 15/162 (9%)
Query: 941 DQEEERKRQER--WQKEQDRLLQEKYQREQEKL--REEWQRAKQEAERENSKYLDEELMV 996
+QEE+ +RQE W+KE EK +R++E + +EE R ++E E + + + +
Sbjct: 332 EQEEKMRRQEEMMWEKE------EKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEM 385
Query: 997 LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQD 1055
+ + E + E + K + E R E+E+RQ QE + + K + Q+
Sbjct: 386 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR--EQEKRQEQEAKMWRQEEKIREQE 443
Query: 1056 QLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAE 1097
+ + E+E+K +Q ++ EQ++++ EE+++ EE RQ E
Sbjct: 444 EKIREQEKKMWRQEEKIHEQEKIR--EEEKRQEQEEMWRQEE 483
Score = 37.7 bits (86), Expect = 0.077
Identities = 37/194 (19%), Positives = 84/194 (43%), Gaps = 18/194 (9%)
Query: 388 EAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLK 447
E IRE K R E +++K + M E ++ ++ +E+ +K++ Q
Sbjct: 328 EKIREQEE---KMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQ-- 382
Query: 448 EQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQN 507
++ W+ + + K + + +++EE+ + E++ E+ KR + K Q+ + +
Sbjct: 383 -EEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIRE 441
Query: 508 QKSTVPSR--------RRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATY-PSEIP 558
Q+ + + +++ + + EE KR E Q E++ E+ + E
Sbjct: 442 QEEKIREQEKKMWRQEEKIHEQEKIREEEKR---QEQEEMWRQEEKIHEQEEIWRQKEKM 498
Query: 559 KEDSTTFAKREDRV 572
E K+E++V
Sbjct: 499 HEQEEKIRKQEEKV 512
Score = 35.0 bits (79), Expect = 0.50
Identities = 33/174 (18%), Positives = 83/174 (47%), Gaps = 17/174 (9%)
Query: 426 EDVQNLRQLRYEEMQKIKSQ---LKEQDQKW--QDDLAKWKDRRKSYTSDLQKKKEEREE 480
E +Q + E+ +KI+ Q ++EQ++K Q+++ K+ + ++ +KEE+
Sbjct: 307 EKIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMR 366
Query: 481 IEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLE-EGKRPPTMTVSEA 539
+++ + + + + +EM+ ++E + ++ +M+ + + E E KR + E
Sbjct: 367 RQEEMMWEKEEKMRRQEEMMWEKEEKIRE----LEEKMHEQEKIREQEEKRQEEEKIREQ 422
Query: 540 SYQSE------RVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQ 587
+ E R EEK +I +E ++E+++ + ++ + +EQ
Sbjct: 423 EKRQEQEAKMWRQEEKIREQEEKI-REQEKKMWRQEEKIHEQEKIREEEKRQEQ 475
Score = 35.0 bits (79), Expect = 0.50
Identities = 35/191 (18%), Positives = 84/191 (43%), Gaps = 23/191 (12%)
Query: 388 EAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLK 447
E I E + +K M E+ + E + E + +R+ + E+M + + +++
Sbjct: 483 EKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE-QEEKMWRQEEKIR 541
Query: 448 EQDQKWQDDLAK------WKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQ 501
EQ++ W+++ W++ ++ D ++EE+ I +Q EK R + +E +
Sbjct: 542 EQEEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEK--IREQE-EKVWRQEEKIREQEE 598
Query: 502 DRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKED 561
R+ Q +K M+ ++ + E + + Q E++ E+ E+ +E
Sbjct: 599 KRQEQEEK--------MWKQEEKIREQEEKIQEQEEKIREQEEKIREQ-----EEMTQEQ 645
Query: 562 STTFAKREDRV 572
++E+++
Sbjct: 646 EEKMGEQEEKM 656
Score = 33.9 bits (76), Expect = 1.1
Identities = 31/171 (18%), Positives = 78/171 (45%), Gaps = 12/171 (7%)
Query: 385 KRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKS 444
K WE E R + ++ R +KI + + + + RQ + E+M K +
Sbjct: 558 KIWE---EEKRQEQEDKMW--RQEEKIREQEEKVWRQEEKIREQEEKRQEQEEKMWKQEE 612
Query: 445 QLKEQDQKWQDDLAKWKDR------RKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKE 498
+++EQ++K Q+ K +++ ++ T + ++K E+EE + EK + +T
Sbjct: 613 KIREQEEKIQEQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEETMWR 672
Query: 499 MLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 549
+++ + +K ++ +++++E + + Q E+++E+
Sbjct: 673 Q-EEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQ 722
Score = 32.7 bits (73), Expect = 2.5
Identities = 28/181 (15%), Positives = 81/181 (44%), Gaps = 28/181 (15%)
Query: 387 WEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQL--RYEEMQKIKS 444
WE + ++R ++ +M E+ E + ++ E + +R+L + E +KI+
Sbjct: 359 WE---KEEKMRRQEEMMWEK-------EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 408
Query: 445 Q---------LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER------EEIEKQALEKS 489
Q ++EQ+++ + + W+ K + + +++E+ E+I +Q +
Sbjct: 409 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIRE 468
Query: 490 KRSSKTFKEMLQDRESQNQKSTV-PSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEE 548
+ + +EM + E +++ + + +M+ ++ + + + + Q E++ E
Sbjct: 469 EEKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIRE 528
Query: 549 K 549
+
Sbjct: 529 Q 529
>gi|239745153 PREDICTED: similar to Putative golgin subfamily A member
6-like protein 6 [Homo sapiens]
Length = 655
Score = 73.9 bits (180), Expect = 1e-12
Identities = 46/189 (24%), Positives = 94/189 (49%), Gaps = 11/189 (5%)
Query: 941 DQEEERKRQERWQKEQDRLLQEKYQ---REQEKLREEWQRAKQEAERENSKYLDEELMVL 997
+QEE+ RQE +EQD +QE+ + R++EK+RE+ ++ +++ R+ K +++ +
Sbjct: 364 EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423
Query: 998 SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKP---- 1053
E E + K + E EEE+ Q QEE + + K
Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE 483
Query: 1054 ----QDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQY 1109
Q++L+ + E+ WEQ+ + ++++++ + E+ + E+ +RQ E RE VR++Q
Sbjct: 484 KTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQ 543
Query: 1110 RRPVDSYDI 1118
+ ++
Sbjct: 544 EEKMQEQEV 552
Score = 56.2 bits (134), Expect = 2e-07
Identities = 39/178 (21%), Positives = 93/178 (52%), Gaps = 17/178 (9%)
Query: 939 VWDQEEERKRQERWQKEQD---RLLQEKYQREQEKLREEWQRAKQEAE---RENSKYLDE 992
+W QEE+ + QE EQ+ R +EK R++EK+ E+ ++ +++ + R+ K ++
Sbjct: 299 MWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ 358
Query: 993 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1052
E + + +E + + E + R+ + E+E ++ QE++ +++ +
Sbjct: 359 EEKIREQEE-KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKR-QEKMWRQEKKMR 416
Query: 1053 PQDQLVIERERK-WEQ--------QLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1101
QD+ + E+E + W Q ++ ++QE+K + E + Q+ + Q+++ +I+R+
Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Score = 56.2 bits (134), Expect = 2e-07
Identities = 52/204 (25%), Positives = 103/204 (50%), Gaps = 19/204 (9%)
Query: 941 DQEEERK----RQERWQKEQDRLLQEKYQ---REQEKLRE--EWQRAKQEAERENSKYLD 991
+QEE+R+ RQE+ +EQD ++E+ + R++EK+RE E + ++E RE + +
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458
Query: 992 EELMVLSSNSMSLTTREPSLATWEA-TW------SEGSKSSDREGTRAGEEERRQPQEEV 1044
EE + + +E + E TW + K ++E +EE+ QEE
Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518
Query: 1045 VHEDQGK-KPQDQLVIERE-RKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1102
+ E + K + Q++ + E+E R W+Q+ + ++++ RLQ E + ++ + RE+
Sbjct: 519 MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRES 578
Query: 1103 SVRIYQYRRPVDSYDIPKTEEASS 1126
+ P+ ++ K++EA S
Sbjct: 579 GSQRLPTLTPILQVEL-KSQEAQS 601
Score = 48.5 bits (114), Expect = 4e-05
Identities = 58/233 (24%), Positives = 105/233 (45%), Gaps = 31/233 (13%)
Query: 881 ESKEING-IHDESNAFESKASE-SISLKNLKR---RSQFFEQGSSDSVVPDLPVPTISAP 935
E KE N + ++ ES+ SE +++K+LKR R+Q V D + +
Sbjct: 215 ELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSV 274
Query: 936 SRWVWDQEEERKRQERWQKEQDRLL---QEKYQREQEKLREEWQRAKQEAERENSKYLDE 992
S + Q EE + ++Q+ + +EK Q ++EK+ E+ + + E+E + E
Sbjct: 275 SAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR---EQEEKMWRQE 331
Query: 993 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1052
E M + RE W E R EE+ R+ +E++ +++ +
Sbjct: 332 EKM----HEQEEKIREQEDKMWR----------QEEKIREQEEKIREQEEKMWRQEEKIR 377
Query: 1053 PQDQLVIERERKWEQQLQE----EQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1101
QD+ + E+E E QE EQE+KR + ++K+ E+ ++ E E E
Sbjct: 378 EQDEKIQEQEE--EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE 428
Score = 41.2 bits (95), Expect = 0.007
Identities = 22/54 (40%), Positives = 36/54 (66%), Gaps = 7/54 (12%)
Query: 939 VWDQEEERKRQER--WQKEQDRLLQ-EKYQREQEKLREE----WQRAKQEAERE 985
+W+QEE+ RQE W++E+ Q EK QR++EK+RE+ WQ+ ++ E+E
Sbjct: 498 IWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Score = 39.3 bits (90), Expect = 0.027
Identities = 43/224 (19%), Positives = 100/224 (44%), Gaps = 8/224 (3%)
Query: 383 DLKRWEAIREASRLRHKKRLMVE--RLFQKIYGENGSKSMSDVSAEDVQNL-RQLRYEEM 439
DLKR + A L +++L VE RL +++ + +K + V ++ NL Q + E+M
Sbjct: 243 DLKR--KLERAQLLLPQQQLQVEADRLGKELQSVS-AKLQAQVEENELWNLLNQQQEEKM 299
Query: 440 QKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEM 499
+ + +++EQ++K + K +++ + +K E+ E+I +Q +K R + +E
Sbjct: 300 WRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQE-DKMWRQEEKIREQ 358
Query: 500 LQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPK 559
+ Q +K ++ D+ ++E + + Q E+ +EK ++ +
Sbjct: 359 EEKIREQEEKMW-RQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMRE 417
Query: 560 EDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQME 603
+D + E+ E ++ + + L + + + E
Sbjct: 418 QDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461
Score = 38.5 bits (88), Expect = 0.045
Identities = 31/169 (18%), Positives = 75/169 (44%), Gaps = 10/169 (5%)
Query: 381 EADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQ 440
E D K E E R K R E+ +K++ + D + + EEM
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE-------EEMW 430
Query: 441 KIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEML 500
+ + +++E ++ QD K ++ + + +K +E+ E+I++Q + ++ KT++
Sbjct: 431 RQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR--- 487
Query: 501 QDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 549
Q++ + ++ +M+ ++ + E + + Q E++ E+
Sbjct: 488 QEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQ 536
Score = 37.4 bits (85), Expect = 0.10
Identities = 31/176 (17%), Positives = 86/176 (48%), Gaps = 13/176 (7%)
Query: 426 EDVQNLRQLRYEEMQKIKSQLKEQDQK---WQDDLAKWKDRRKSYTSDLQKKKEEREEIE 482
E ++ + R E+M + + +++EQD+K ++++ + +++ + +Q ++E+ E+E
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVE 454
Query: 483 KQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQ 542
++ E+ ++ + +E +Q +E + Q+ + R+ + +L++ ++ + E +
Sbjct: 455 EKMQEEEEKMQEQ-EEKIQRQEEKIQEQEEKTWRQ----EKLLKQEEK-----IWEQEEK 504
Query: 543 SERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSR 598
R EEK ++ +++ + E E++L Q ++ L L R
Sbjct: 505 MWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560
>gi|239745127 PREDICTED: similar to Putative golgin subfamily A member
6-like protein 6 [Homo sapiens]
Length = 655
Score = 73.9 bits (180), Expect = 1e-12
Identities = 46/189 (24%), Positives = 94/189 (49%), Gaps = 11/189 (5%)
Query: 941 DQEEERKRQERWQKEQDRLLQEKYQ---REQEKLREEWQRAKQEAERENSKYLDEELMVL 997
+QEE+ RQE +EQD +QE+ + R++EK+RE+ ++ +++ R+ K +++ +
Sbjct: 364 EQEEKMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIR 423
Query: 998 SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKP---- 1053
E E + K + E EEE+ Q QEE + + K
Sbjct: 424 EQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEE 483
Query: 1054 ----QDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQY 1109
Q++L+ + E+ WEQ+ + ++++++ + E+ + E+ +RQ E RE VR++Q
Sbjct: 484 KTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQ 543
Query: 1110 RRPVDSYDI 1118
+ ++
Sbjct: 544 EEKMQEQEV 552
Score = 56.2 bits (134), Expect = 2e-07
Identities = 39/178 (21%), Positives = 93/178 (52%), Gaps = 17/178 (9%)
Query: 939 VWDQEEERKRQERWQKEQD---RLLQEKYQREQEKLREEWQRAKQEAE---RENSKYLDE 992
+W QEE+ + QE EQ+ R +EK R++EK+ E+ ++ +++ + R+ K ++
Sbjct: 299 MWRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQEDKMWRQEEKIREQ 358
Query: 993 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1052
E + + +E + + E + R+ + E+E ++ QE++ +++ +
Sbjct: 359 EEKIREQEE-KMWRQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKR-QEKMWRQEKKMR 416
Query: 1053 PQDQLVIERERK-WEQ--------QLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1101
QD+ + E+E + W Q ++ ++QE+K + E + Q+ + Q+++ +I+R+
Sbjct: 417 EQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQ 474
Score = 56.2 bits (134), Expect = 2e-07
Identities = 52/204 (25%), Positives = 103/204 (50%), Gaps = 19/204 (9%)
Query: 941 DQEEERK----RQERWQKEQDRLLQEKYQ---REQEKLRE--EWQRAKQEAERENSKYLD 991
+QEE+R+ RQE+ +EQD ++E+ + R++EK+RE E + ++E RE + +
Sbjct: 399 EQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQ 458
Query: 992 EELMVLSSNSMSLTTREPSLATWEA-TW------SEGSKSSDREGTRAGEEERRQPQEEV 1044
EE + + +E + E TW + K ++E +EE+ QEE
Sbjct: 459 EEEEKMQEQEEKIQRQEEKIQEQEEKTWRQEKLLKQEEKIWEQEEKMWRQEEKMWEQEEK 518
Query: 1045 VHEDQGK-KPQDQLVIERE-RKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1102
+ E + K + Q++ + E+E R W+Q+ + ++++ RLQ E + ++ + RE+
Sbjct: 519 MQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEERLGKLGQKAELLGGAGRES 578
Query: 1103 SVRIYQYRRPVDSYDIPKTEEASS 1126
+ P+ ++ K++EA S
Sbjct: 579 GSQRLPTLTPILQVEL-KSQEAQS 601
Score = 48.5 bits (114), Expect = 4e-05
Identities = 58/233 (24%), Positives = 105/233 (45%), Gaps = 31/233 (13%)
Query: 881 ESKEING-IHDESNAFESKASE-SISLKNLKR---RSQFFEQGSSDSVVPDLPVPTISAP 935
E KE N + ++ ES+ SE +++K+LKR R+Q V D + +
Sbjct: 215 ELKEKNAELQEKLRLVESEKSEIQLNVKDLKRKLERAQLLLPQQQLQVEADRLGKELQSV 274
Query: 936 SRWVWDQEEERKRQERWQKEQDRLL---QEKYQREQEKLREEWQRAKQEAERENSKYLDE 992
S + Q EE + ++Q+ + +EK Q ++EK+ E+ + + E+E + E
Sbjct: 275 SAKLQAQVEENELWNLLNQQQEEKMWRQEEKIQEQEEKMCEQELKIR---EQEEKMWRQE 331
Query: 993 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1052
E M + RE W E R EE+ R+ +E++ +++ +
Sbjct: 332 EKM----HEQEEKIREQEDKMWR----------QEEKIREQEEKIREQEEKMWRQEEKIR 377
Query: 1053 PQDQLVIERERKWEQQLQE----EQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1101
QD+ + E+E E QE EQE+KR + ++K+ E+ ++ E E E
Sbjct: 378 EQDEKIQEQEE--EMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQEEE 428
Score = 41.2 bits (95), Expect = 0.007
Identities = 22/54 (40%), Positives = 36/54 (66%), Gaps = 7/54 (12%)
Query: 939 VWDQEEERKRQER--WQKEQDRLLQ-EKYQREQEKLREE----WQRAKQEAERE 985
+W+QEE+ RQE W++E+ Q EK QR++EK+RE+ WQ+ ++ E+E
Sbjct: 498 IWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQE 551
Score = 39.3 bits (90), Expect = 0.027
Identities = 43/224 (19%), Positives = 100/224 (44%), Gaps = 8/224 (3%)
Query: 383 DLKRWEAIREASRLRHKKRLMVE--RLFQKIYGENGSKSMSDVSAEDVQNL-RQLRYEEM 439
DLKR + A L +++L VE RL +++ + +K + V ++ NL Q + E+M
Sbjct: 243 DLKR--KLERAQLLLPQQQLQVEADRLGKELQSVS-AKLQAQVEENELWNLLNQQQEEKM 299
Query: 440 QKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEM 499
+ + +++EQ++K + K +++ + +K E+ E+I +Q +K R + +E
Sbjct: 300 WRQEEKIQEQEEKMCEQELKIREQEEKMWRQEEKMHEQEEKIREQE-DKMWRQEEKIREQ 358
Query: 500 LQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPK 559
+ Q +K ++ D+ ++E + + Q E+ +EK ++ +
Sbjct: 359 EEKIREQEEKMW-RQEEKIREQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMRE 417
Query: 560 EDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQME 603
+D + E+ E ++ + + L + + + E
Sbjct: 418 QDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVEEKMQEEE 461
Score = 38.5 bits (88), Expect = 0.045
Identities = 31/169 (18%), Positives = 75/169 (44%), Gaps = 10/169 (5%)
Query: 381 EADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQ 440
E D K E E R K R E+ +K++ + D + + EEM
Sbjct: 378 EQDEKIQEQEEEMWRQEEKIREQEEKRQEKMWRQEKKMREQDEKIREQE-------EEMW 430
Query: 441 KIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEML 500
+ + +++E ++ QD K ++ + + +K +E+ E+I++Q + ++ KT++
Sbjct: 431 RQEEKIRELEEMMQDQEEKLREVEEKMQEEEEKMQEQEEKIQRQEEKIQEQEEKTWR--- 487
Query: 501 QDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 549
Q++ + ++ +M+ ++ + E + + Q E++ E+
Sbjct: 488 QEKLLKQEEKIWEQEEKMWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQ 536
Score = 37.4 bits (85), Expect = 0.10
Identities = 31/176 (17%), Positives = 86/176 (48%), Gaps = 13/176 (7%)
Query: 426 EDVQNLRQLRYEEMQKIKSQLKEQDQK---WQDDLAKWKDRRKSYTSDLQKKKEEREEIE 482
E ++ + R E+M + + +++EQD+K ++++ + +++ + +Q ++E+ E+E
Sbjct: 395 EKIREQEEKRQEKMWRQEKKMREQDEKIREQEEEMWRQEEKIRELEEMMQDQEEKLREVE 454
Query: 483 KQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQ 542
++ E+ ++ + +E +Q +E + Q+ + R+ + +L++ ++ + E +
Sbjct: 455 EKMQEEEEKMQEQ-EEKIQRQEEKIQEQEEKTWRQ----EKLLKQEEK-----IWEQEEK 504
Query: 543 SERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSR 598
R EEK ++ +++ + E E++L Q ++ L L R
Sbjct: 505 MWRQEEKMWEQEEKMQEQEEKMQRQEEKMREQEVRLWQQEEKMQEQEVRLQELEER 560
>gi|239745095 PREDICTED: hypothetical protein LOC645202 [Homo sapiens]
Length = 570
Score = 73.6 bits (179), Expect = 1e-12
Identities = 48/186 (25%), Positives = 93/186 (50%), Gaps = 8/186 (4%)
Query: 939 VWDQEEERKRQERWQKEQDRLLQEKYQR---EQEKL---REEWQRAKQEAERENSKYLDE 992
+W QEE+ + QE +EQ+ ++QE+ ++ ++EK+ EE Q +++ R+ K ++
Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ 444
Query: 993 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK- 1051
E + E E + K ++E +EE+ + QEE + E + K
Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKI 504
Query: 1052 KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQ-KRQAEIERETSVRIYQYR 1110
+ Q++ + E+E ++Q ++ EQ+ E EE+ + EE+ +RQ E RE VR+ Q
Sbjct: 505 REQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMREQEVRLRQQE 564
Query: 1111 RPVDSY 1116
+ +
Sbjct: 565 EKMQEH 570
Score = 70.9 bits (172), Expect = 8e-12
Identities = 49/188 (26%), Positives = 92/188 (48%), Gaps = 21/188 (11%)
Query: 939 VWDQEEERKRQER--WQKEQDRLLQEKYQREQEKLREEWQRAKQEAE------------- 983
+W++EE+ +RQE W+KE+ E+ EQEK+RE+ ++ ++E +
Sbjct: 325 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK 384
Query: 984 --RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQ 1041
R+ K ++E + M E E W + + ++E +EE+ + Q
Sbjct: 385 MWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQ 444
Query: 1042 EEVVHEDQGK-KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAE--- 1097
E+ + E + K + Q++++ E+E K +Q + EQ+ E EE+ R EE+ R+ E
Sbjct: 445 EKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKI 504
Query: 1098 IERETSVR 1105
E+E +R
Sbjct: 505 REQEEKIR 512
Score = 63.9 bits (154), Expect = 1e-09
Identities = 47/184 (25%), Positives = 92/184 (50%), Gaps = 25/184 (13%)
Query: 939 VWDQEEERKRQERWQKEQDRLL-QEKYQREQEKLREEWQRAKQEAE--RENSKYLDEELM 995
+W++EE+ + E EQ+++ QE+ ++E+EK+RE+ +R +QEA+ R+ K ++E
Sbjct: 339 MWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK 398
Query: 996 VLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQ 1054
+ M E E W + + ++E +EE+ + QE+ + E + K + Q
Sbjct: 399 IREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKIREQEKKIREQEEKIREQ 458
Query: 1055 DQLVIERERKW-------------------EQQLQEE--QEQKRLQAEAEEQKRPAEEQK 1093
++++ E+E K + + QEE +EQ++ E EE+ R EE
Sbjct: 459 EEMMQEQEEKMGEQEGKMCEQEAKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMM 518
Query: 1094 RQAE 1097
++ E
Sbjct: 519 QEQE 522
Score = 62.4 bits (150), Expect = 3e-09
Identities = 60/254 (23%), Positives = 124/254 (48%), Gaps = 25/254 (9%)
Query: 881 ESKEING-IHDESNAFESKASE-SISLKNLKRRSQFFE--------QGSSDSVVPDLPVP 930
E KE N + ++ ES+ SE +++K LKR+ + + Q +D + +L
Sbjct: 206 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 265
Query: 931 TISAPSRW----VWDQEEERKRQERW-QKEQDRLLQEKYQREQEKLREEWQRAKQEAE-- 983
+ ++ +W++ +++ ++ W Q+E+ + +EK Q ++EK+RE+ ++ +++ E
Sbjct: 266 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEREEKIQEQEEKIREQEEKMRRQEEMM 325
Query: 984 --RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQ 1041
+E EE+M + E + E + K + E R E+E+RQ Q
Sbjct: 326 WEKEEKMRRQEEMMW--EKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR--EQEKRQEQ 381
Query: 1042 EEVVHEDQGK-KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQ-KRQAEIE 1099
E + + K + Q++ + E+E ++Q ++ EQ+ E EE+ + EE+ +RQ E
Sbjct: 382 EAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQEQEEKMRRQEEKI 441
Query: 1100 RETSVRIYQYRRPV 1113
RE +I + +
Sbjct: 442 REQEKKIREQEEKI 455
Score = 35.0 bits (79), Expect = 0.50
Identities = 28/152 (18%), Positives = 70/152 (46%), Gaps = 6/152 (3%)
Query: 429 QNLRQLRYEEM--QKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQAL 486
Q + R EEM +K + ++++ W+ + + K + + +++EE+ + E++
Sbjct: 314 QEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIR 373
Query: 487 EKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERV 546
E+ KR + K Q+ + + Q+ + + M + + G++ M E Q +
Sbjct: 374 EQEKRQEQEAKMWRQEEKIREQEEKIREQEEMMQ-EQEEKMGEQEEKMWEQEEEMQEQ-- 430
Query: 547 EEKGATYPSEIPKEDSTTFAKREDRVTTEIQL 578
EEK +I +E ++E+++ + ++
Sbjct: 431 EEKMRRQEEKI-REQEKKIREQEEKIREQEEM 461
Score = 33.9 bits (76), Expect = 1.1
Identities = 34/196 (17%), Positives = 86/196 (43%), Gaps = 4/196 (2%)
Query: 388 EAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLK 447
E IRE + R ++ + R +KI + + ++ + + E+M + + +++
Sbjct: 370 EKIREQEK-RQEQEAKMWRQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMWEQEEEMQ 428
Query: 448 EQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKE--MLQDRES 505
EQ++K + K +++ K +K +E+ E +++Q + ++ K ++ +Q++E
Sbjct: 429 EQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMGEQEGKMCEQEAKMQEQEE 488
Query: 506 QNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTF 565
+ ++ R + + EE R + E + EEK ++ +++
Sbjct: 489 KMRRQEEKIREQEKKIRE-QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMR 547
Query: 566 AKREDRVTTEIQLPSQ 581
+ E E++L Q
Sbjct: 548 RQEEKMREQEVRLRQQ 563
Score = 31.2 bits (69), Expect = 7.2
Identities = 23/120 (19%), Positives = 59/120 (49%), Gaps = 8/120 (6%)
Query: 433 QLRYEEMQKIKSQLKEQDQKW--QDDLAKWKDRRKSYTSDLQKKKEER-EEIEKQALEKS 489
Q R E++Q+ + +++EQ++K Q+++ K+ + ++ +KEE+ E+E++ E+
Sbjct: 298 QEREEKIQEQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQE 357
Query: 490 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 549
K + K +++ + +K + + + E+ ++ + E + EEK
Sbjct: 358 KIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEK-----IREQEEMMQEQEEK 412
>gi|239745089 PREDICTED: golgi autoantigen, golgin subfamily a-like
[Homo sapiens]
Length = 828
Score = 73.2 bits (178), Expect = 2e-12
Identities = 75/332 (22%), Positives = 153/332 (46%), Gaps = 44/332 (13%)
Query: 810 KFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEK---SSNLS 866
KF + E ++ + + H +++R A S K D E+ S L
Sbjct: 117 KFEDGNLGESKDLAGRLHHSWHFAGELQRALSAVSTWHKKADRYIEELTKERDALSLELY 176
Query: 867 VTTDFSESLQSSNIESKEINGIHDESNAFESKASE-SISLKNLKRRSQFFEQGSSDSVVP 925
T +E L+ N E +E + ES+ SE +++K LKR+ + + ++P
Sbjct: 177 RNTITNEELKKKNAELQE------KLRLAESEKSEIQLNVKELKRKLE-----RAKFLLP 225
Query: 926 DLPVPTISAPSRWVWDQEEE--------RKRQERWQKEQDRLLQ---------EKYQREQ 968
+ T+ +W QEEE RK++E+ ++++RL + EK +R++
Sbjct: 226 QVQTNTLQEE---MWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMRRQE 282
Query: 969 EKLREEWQRAKQEAE--RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSD 1026
++LRE+ + +++ + RE K ++E + E E W + + +
Sbjct: 283 KRLREQEKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWE 342
Query: 1027 REGTRAGEEERRQPQEEVVHE-DQGKKPQDQLVIERERKWEQQ--LQEE----QEQKRLQ 1079
+E +E++ + QEE + E D+ + +++ + E+E+ WEQ+ +QEE + +K+++
Sbjct: 343 QEKQMREQEQKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMR 402
Query: 1080 AEAEEQKRPAEEQKRQAEIERETSVRIYQYRR 1111
E E + E+ ++Q E E + +Q +R
Sbjct: 403 EEEETMREQEEKMQKQEENMWEQEEKEWQQQR 434
Score = 66.6 bits (161), Expect = 2e-10
Identities = 59/212 (27%), Positives = 99/212 (46%), Gaps = 36/212 (16%)
Query: 940 WDQEE---------ERKRQERWQKEQDRLLQEKYQREQEKLREE----WQRAKQEAEREN 986
WDQEE ER+++ R ++E R +EK Q ++EK+RE+ W++ ++ E+E
Sbjct: 550 WDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEE 609
Query: 987 SKYLDEELM--------VLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERR 1038
+ EE M + M E E W + K ++E +EE+
Sbjct: 610 KMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKM 669
Query: 1039 QPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAE---AEEQKRPAEEQKRQ 1095
Q QEE + E Q +K Q Q E++++E++E+ R Q E +E+K +E+K
Sbjct: 670 QGQEEKMRE-QEEKMQGQ---------EEKMREQEEKMRGQEEKMWGQEEKMWGQEEKMW 719
Query: 1096 AEIE-RETSVRIYQYRRPVDSYDIPKTEEASS 1126
+ E RE RI + + +P+ EE S
Sbjct: 720 GQEEMREKEERIRDQKEKMQE-RLPEHEERCS 750
Score = 66.2 bits (160), Expect = 2e-10
Identities = 49/267 (18%), Positives = 121/267 (45%), Gaps = 24/267 (8%)
Query: 939 VWDQEEERKRQER--------WQKEQDRLLQEKYQREQEKLREE---WQRAK----QEAE 983
+W+QEE+ +Q+R W++E+ + +EK ++EK+R++ W + K QE
Sbjct: 422 MWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKM 481
Query: 984 RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEE 1043
RE + E+ + + +E E W + + ++E R E+++ QEE
Sbjct: 482 REQEDQMWEQEEKMRDQEQKMWDQE------ERMWEQDERLREKE-ERMREQKKMWQQEE 534
Query: 1044 VVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETS 1103
+ E++ + Q++ ++E K ++ + + +K+++ E E + E+ + Q E RE
Sbjct: 535 KMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQE 594
Query: 1104 VRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTEL--DDYSTNKNGNNKYLDQIGN 1161
++++ + + E+ + + +K + E+ + + K +Q
Sbjct: 595 EKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEK 654
Query: 1162 MTSSQRRSKKEQVPSGAELERQQILQE 1188
M + + ++++ + E+ + +E
Sbjct: 655 MREQEEKMREQEEKMQGQEEKMREQEE 681
Score = 65.5 bits (158), Expect = 3e-10
Identities = 50/179 (27%), Positives = 92/179 (51%), Gaps = 25/179 (13%)
Query: 939 VWDQEE---------ERKRQERWQKEQDRLLQEKYQREQEKLRE----EWQRAKQEAERE 985
+W+QEE ER+++ R ++E R +EK Q+++E + E EWQ+ + ++E
Sbjct: 381 MWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKE 440
Query: 986 NSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVV 1045
K ++E M + +E + E W + K +E R E++ + +E++
Sbjct: 441 --KLWEQEKM--QEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKM- 495
Query: 1046 HEDQGKKPQDQLVIERERKWEQ--QLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1102
DQ +K DQ ER WEQ +L+E++E+ R Q + +Q+ E+K+ E E++T
Sbjct: 496 -RDQEQKMWDQ----EERMWEQDERLREKEERMREQKKMWQQEEKMREEKKTQEQEKKT 549
Score = 65.5 bits (158), Expect = 3e-10
Identities = 70/292 (23%), Positives = 126/292 (43%), Gaps = 40/292 (13%)
Query: 939 VWDQEEERKRQER--WQK-----EQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLD 991
+W+QEE+ + QE+ W + EQD L+EK +R +E+ ++ WQ ++E RE K
Sbjct: 488 MWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQ-KKMWQ--QEEKMREEKK--- 541
Query: 992 EELMVLSSNSMSLTTREPSLATW--EATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ 1049
T+E TW E E + +RE EEE + QEE + E +
Sbjct: 542 --------------TQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQE 587
Query: 1050 GK-KPQDQLVIERERKWEQQLQE--EQEQKRLQAEAEEQKRPAEEQK-RQAEIERETSVR 1105
K + Q++ + E+E K ++Q ++ EQE+K + E E++ + EE Q E +E +
Sbjct: 588 EKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEK 647
Query: 1106 IYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSS 1165
+++ + + E+ + G K R E + K +Q M
Sbjct: 648 MWEQEEKMREQEEKMREQEEK--MQGQEEKMREQEE-----KMQGQEEKMREQEEKMRGQ 700
Query: 1166 QRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLP 1217
+ + ++ + E+ +EMR++ D Q ++E S P
Sbjct: 701 EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQERLPEHEERCSEP 752
Score = 64.3 bits (155), Expect = 8e-10
Identities = 76/339 (22%), Positives = 134/339 (39%), Gaps = 48/339 (14%)
Query: 942 QEEERKRQER----W-QKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMV 996
+E+E + QE+ W Q+E+ R +EK R++E+L W++ KQ E+E EE M
Sbjct: 306 REQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERL---WEQEKQMREQEQKMRDQEERM- 361
Query: 997 LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGE-------------EERRQPQEE 1043
L +E + E W + K + E R E EE+ Q QEE
Sbjct: 362 -WEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEE 420
Query: 1044 VVHEDQGKKPQDQ-LVIERERKWEQQLQEEQEQKRLQAE-----------------AEEQ 1085
+ E + K+ Q Q L ++E+ WEQ+ +EQE+K + E +E+
Sbjct: 421 NMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEK 480
Query: 1086 KRPAEEQK-RQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDD 1144
R E+Q Q E R+ +++ + D E+ + + + ++ +
Sbjct: 481 MREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEER--MREQKKMWQQEEKMRE 538
Query: 1145 YSTNKNGNNKYLDQIGNMTSSQR---RSKKEQVPSGAELERQQILQEMRKRTPLHNDNSW 1201
+ K DQ M +R R KK + E+++ +QE ++ + W
Sbjct: 539 EKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMW 598
Query: 1202 IRQRSASVNKEPV-SLPGIMRRGESLDNLDSPRSNSWRQ 1239
++ +E + M E D + W Q
Sbjct: 599 EQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQ 637
Score = 50.1 bits (118), Expect = 2e-05
Identities = 54/253 (21%), Positives = 99/253 (39%), Gaps = 27/253 (10%)
Query: 817 KEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWIDATSGIYNSEKSSNLSVTTDFSESL- 875
+E EE M + ++ +R K E K D + E+ E +
Sbjct: 517 REKEERMREQKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMM 576
Query: 876 --QSSNIESKEINGIHDESNAFESKAS-ESISLKNLKRRSQFFEQGSSDSVVPDLPVPTI 932
Q ++ +E E +E + + K ++ + +EQ D +
Sbjct: 577 REQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKM--------- 627
Query: 933 SAPSRWVWDQEEERKRQER--WQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYL 990
+W+QEE+ + QE W++E+ QE+ REQ EE + ++E RE + +
Sbjct: 628 QEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ----EEKMQGQEEKMREQEEKM 683
Query: 991 DEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQG 1050
+ + + +E E W + K +E G+EE R+ +E + DQ
Sbjct: 684 QGQEEKMREQEEKMRGQE------EKMWGQEEKMWGQEEKMWGQEEMREKEERI--RDQK 735
Query: 1051 KKPQDQLVIERER 1063
+K Q++L ER
Sbjct: 736 EKMQERLPEHEER 748
Score = 41.6 bits (96), Expect = 0.005
Identities = 26/123 (21%), Positives = 61/123 (49%), Gaps = 2/123 (1%)
Query: 429 QNLRQLRYEEMQKIKSQLKEQDQKWQDDLAK-WKDRRKSYTSDLQ-KKKEEREEIEKQAL 486
Q + R E+M++ + Q+ EQ++K +D K W + + D + ++KEER +K+
Sbjct: 471 QEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWDQEERMWEQDERLREKEERMREQKKMW 530
Query: 487 EKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERV 546
++ ++ + K Q++++ +Q+ + RM + + E + + Q E++
Sbjct: 531 QQEEKMREEKKTQEQEKKTWDQEEKMREEERMREREKKMREEEEMMREQEEKMQEQEEKM 590
Query: 547 EEK 549
E+
Sbjct: 591 REQ 593
Score = 40.8 bits (94), Expect = 0.009
Identities = 28/133 (21%), Positives = 62/133 (46%), Gaps = 12/133 (9%)
Query: 381 EADLKRW---EAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYE 437
E + K W E +RE R+R +++ M E E + + E + +R+ + E
Sbjct: 544 EQEKKTWDQEEKMREEERMREREKKMREE-------EEMMREQEEKMQEQEEKMRE-QEE 595
Query: 438 EMQKIKSQLKEQDQK-WQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 496
+M + + +++EQ++K W+ + W+ + + ++ E+EE ++ EK +
Sbjct: 596 KMWEQEEKMQEQEEKMWEQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKM 655
Query: 497 KEMLQDRESQNQK 509
+E + Q +K
Sbjct: 656 REQEEKMREQEEK 668
Score = 38.9 bits (89), Expect = 0.035
Identities = 42/219 (19%), Positives = 98/219 (44%), Gaps = 25/219 (11%)
Query: 385 KRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRY-----EEM 439
K W R+ RLR ++ M E+ + E + E + LR+ + E+M
Sbjct: 256 KMW---RQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQM 312
Query: 440 QKIKSQLKEQDQKWQDDLAK-WKDRRKSYTSDLQKKKEERE---------EIEKQALEKS 489
Q+ + ++ EQ++K ++ K W+ + + + Q +++E++ E +++ EK
Sbjct: 313 QEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMREQEQKMRDQEERMWEQDERLREKE 372
Query: 490 KRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEE-----GKRPPTM-TVSEASYQS 543
+R + K Q+ + Q ++ ++M ++ + E K+ M E +Q
Sbjct: 373 ERMREQEKMWEQEEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQ 432
Query: 544 ERV-EEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQ 581
+R+ E+K + E +E ++E+++ + ++ Q
Sbjct: 433 QRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMWGQ 471
Score = 37.4 bits (85), Expect = 0.10
Identities = 39/213 (18%), Positives = 95/213 (44%), Gaps = 17/213 (7%)
Query: 381 EADLKRWEA-IREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNL----RQLR 435
E +L+ E +RE +LR ++ M E+ + E + + + L +Q+R
Sbjct: 289 EKELREQEKELREQKKLREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMR 348
Query: 436 YEEMQKIKSQ---LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER--------EEIEKQ 484
+E QK++ Q + EQD++ ++ + +++ K + + + ++EER E E+
Sbjct: 349 EQE-QKMRDQEERMWEQDERLREKEERMREQEKMWEQEEKMQEEERIREREKKMREEEET 407
Query: 485 ALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSE 544
E+ ++ K + M + E + Q+ +P ++ + ++E + + Q E
Sbjct: 408 MREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEE 467
Query: 545 RVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQ 577
++ + E +E ++E+++ + Q
Sbjct: 468 MWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQ 500
Score = 36.6 bits (83), Expect = 0.17
Identities = 26/165 (15%), Positives = 77/165 (46%), Gaps = 7/165 (4%)
Query: 385 KRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKS 444
+ WE + RLR K+ M E+ +K++ + + M + Q + EE + +
Sbjct: 508 RMWE---QDERLREKEERMREQ--KKMWQQE--EKMREEKKTQEQEKKTWDQEEKMREEE 560
Query: 445 QLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRE 504
+++E+++K +++ +++ + +K +E+ E++ +Q + ++ K +++ + E
Sbjct: 561 RMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMWE 620
Query: 505 SQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 549
+ + M+ ++ ++E + + Q E++ E+
Sbjct: 621 QEEEDKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 665
Score = 34.7 bits (78), Expect = 0.65
Identities = 25/151 (16%), Positives = 69/151 (45%), Gaps = 12/151 (7%)
Query: 429 QNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEK 488
Q Q + E++ + + ++++Q++ W + W+ + D ++EE+ ++Q +
Sbjct: 445 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQEDQMWEQEEKMRDQEQKMWD 504
Query: 489 SKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKR-----PPTMTVSEASYQS 543
+ E L+++E + ++ +++M+ ++ + E K+ T E +
Sbjct: 505 QEERMWEQDERLREKEERMRE-----QKKMWQQEEKMREEKKTQEQEKKTWDQEEKMREE 559
Query: 544 ERV--EEKGATYPSEIPKEDSTTFAKREDRV 572
ER+ EK E+ +E ++E+++
Sbjct: 560 ERMREREKKMREEEEMMREQEEKMQEQEEKM 590
Score = 34.3 bits (77), Expect = 0.85
Identities = 28/127 (22%), Positives = 60/127 (47%), Gaps = 7/127 (5%)
Query: 388 EAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLK 447
E +R A + + +L V+ L +K+ E + V +Q + EE+++ + +++
Sbjct: 194 EKLRLAESEKSEIQLNVKELKRKL--ERAKFLLPQVQTNTLQEEMWRQEEELREQEKKIR 251
Query: 448 EQDQK-WQDDLA----KWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQD 502
+Q++K W+ + + K R + Q+K+ +E E + EK R K +E +
Sbjct: 252 KQEEKMWRQEERLREQEGKMREQEEKMRRQEKRLREQEKELREQEKELREQKKLREQEEQ 311
Query: 503 RESQNQK 509
+ Q +K
Sbjct: 312 MQEQEEK 318
Score = 33.5 bits (75), Expect = 1.5
Identities = 25/146 (17%), Positives = 69/146 (47%), Gaps = 6/146 (4%)
Query: 388 EAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQ-- 445
E +RE ++ ++ +K++ E K + +Q ++ +E+ +K++ Q
Sbjct: 588 EKMREQEEKMWEQEEKMQEQEEKMW-EQEEKMWEQEEEDKMQEQEEMMWEQEEKMQEQEE 646
Query: 446 -LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRE 504
+ EQ++K ++ K +++ + +K +E+ E+++ Q EK + + + +
Sbjct: 647 KMWEQEEKMREQEEKMREQEEKMQGQEEKMREQEEKMQGQE-EKMREQEEKMRGQEEKMW 705
Query: 505 SQNQKSTVPSRRRMYSFDDVLEEGKR 530
Q +K +M+ +++ E+ +R
Sbjct: 706 GQEEKMW-GQEEKMWGQEEMREKEER 730
Score = 33.1 bits (74), Expect = 1.9
Identities = 21/108 (19%), Positives = 45/108 (41%), Gaps = 10/108 (9%)
Query: 381 EADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQ 440
E + K WE + K R E++ G + E +Q + E+ +
Sbjct: 643 EQEEKMWEQEEKMREQEEKMREQEEKM-------QGQEEKMREQEEKMQGQEEKMREQEE 695
Query: 441 KIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEK 488
K++ Q +++ W + W K + + ++KEER +K+ +++
Sbjct: 696 KMRGQ---EEKMWGQEEKMWGQEEKMWGQEEMREKEERIRDQKEKMQE 740
>gi|169218106 PREDICTED: hypothetical protein, partial [Homo sapiens]
Length = 436
Score = 69.3 bits (168), Expect = 2e-11
Identities = 55/214 (25%), Positives = 104/214 (48%), Gaps = 16/214 (7%)
Query: 898 KASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQD 957
K E + + + R Q + G + V + +E+ R+++E+ +++++
Sbjct: 217 KQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEE 276
Query: 958 RLLQEKYQREQEKL---REEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATW 1014
++L++K Q EQE+ +EE R ++E RE + + E+ + + +E + W
Sbjct: 277 QMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQM--W 334
Query: 1015 EAT---WSEGSKSSDREGTRAGEEERRQPQEEVV--HEDQGKKPQDQLVIERE--RKWEQ 1067
E W + + +E +EE+ Q QEE V E+Q +K ++Q+ + E RK E+
Sbjct: 335 EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEE 394
Query: 1068 QLQEEQ----EQKRLQAEAEEQKRPAEEQKRQAE 1097
Q+ E++ EQK E EEQ +EQ R+ E
Sbjct: 395 QMGEQKEQMGEQKEQMREQEEQMGEQKEQMRKQE 428
Score = 61.6 bits (148), Expect = 5e-09
Identities = 69/288 (23%), Positives = 129/288 (44%), Gaps = 19/288 (6%)
Query: 939 VWDQEEERKRQERWQKEQDRLL--QEKYQREQE-KLRE-EWQRAKQEAE-RENSKYLDEE 993
V +QE + + QE +EQ+ + QE REQE ++RE E Q +QE + RE + E+
Sbjct: 138 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQMGEQ 197
Query: 994 LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERR-QPQEEVV--HEDQG 1050
+ + +E + E E + ++ + GE+E + Q QEE V E+Q
Sbjct: 198 EGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQM 257
Query: 1051 KKPQDQLVIERERKWEQQLQ-----EEQEQKRLQAEAEEQKRPAEEQKRQAEIE-RETSV 1104
+K ++Q+ + E+ EQ+ Q E+ EQ+ E EEQ R EEQ R+ E + RE
Sbjct: 258 RKQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEE 317
Query: 1105 RIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTS 1164
++ + + + E+ + K + + + + K +Q+
Sbjct: 318 QMREQEEQMGKQEEQMWEQKEQMW----EQKEQMWKQEEQMGEQEEQMQKQEEQV-RKQE 372
Query: 1165 SQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1212
Q R ++EQ+ E R+Q Q ++ + +R++ + ++
Sbjct: 373 EQMRKQEEQMRKQEEQMRKQEEQMGEQKEQMGEQKEQMREQEEQMGEQ 420
Score = 52.4 bits (124), Expect = 3e-06
Identities = 68/283 (24%), Positives = 123/283 (43%), Gaps = 23/283 (8%)
Query: 939 VWDQEEERKRQERWQKEQDRLL--QEKYQREQE-KLRE-EWQRAKQEAE-RENSKYLDEE 993
V +QE + + QE +EQ+ + QE REQE ++RE E Q +QE + RE + E+
Sbjct: 110 VREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQ 169
Query: 994 LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGE-EERRQPQEEVV--HEDQG 1050
+ + +E + E E + + GE EE+ Q QEE + E+Q
Sbjct: 170 EGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGEQEEQM 229
Query: 1051 KKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIE-RETSVRIYQY 1109
+K ++Q+ E++ + Q QEEQ QK+ EEQ R EEQ R+ E + RE ++ +
Sbjct: 230 RKQEEQM---GEQEEQVQKQEEQVQKQ-----EEQMRKQEEQMREQEEQMREQEEQMLKQ 281
Query: 1110 RRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRS 1169
+ + + +E R + E ++ + + ++ Q
Sbjct: 282 KEQTEQEEQTGEQEEQM------REQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWE 335
Query: 1170 KKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1212
+KEQ+ E +Q Q + + +R++ + K+
Sbjct: 336 QKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQ 378
Score = 44.7 bits (104), Expect = 6e-04
Identities = 35/169 (20%), Positives = 76/169 (44%), Gaps = 9/169 (5%)
Query: 437 EEMQKIKSQLKEQDQ---KWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 493
E+MQK + Q+ EQ++ K ++ + + +++ + +QK++E+ + E+Q E+ ++
Sbjct: 213 EQMQKQEEQMGEQEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMR 272
Query: 494 KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATY 553
+ ++ML+ +E Q+ + EE R + E Q EE+
Sbjct: 273 EQEEQMLKQKEQTEQEEQTGEQEEQMREQ---EEQMREQEEQMREQEEQMREQEEQMGKQ 329
Query: 554 PSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 602
++ ++ + ++E E Q+ Q EEQ +R + QM
Sbjct: 330 EEQMWEQKEQMWEQKEQMWKQEEQMGEQ---EEQMQKQEEQVRKQEEQM 375
Score = 39.3 bits (90), Expect = 0.027
Identities = 35/169 (20%), Positives = 78/169 (46%), Gaps = 16/169 (9%)
Query: 437 EEMQKIKSQLKEQD---QKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 493
E+M+K + Q+ EQ+ QK ++ + K +++ + +++++E+ E E+Q L++ +++
Sbjct: 227 EQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQTE 286
Query: 494 KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATY 553
+ +E ++E Q ++ R + EE R + E Q + EE+
Sbjct: 287 Q--EEQTGEQEEQMREQEEQMREQ--------EEQMREQEEQMREQEEQMGKQEEQMWEQ 336
Query: 554 PSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 602
++ ++ + + E E Q+ Q EEQ +R + QM
Sbjct: 337 KEQMWEQKEQMWKQEEQMGEQEEQMQKQ---EEQVRKQEEQMRKQEEQM 382
Score = 38.5 bits (88), Expect = 0.045
Identities = 53/256 (20%), Positives = 106/256 (41%), Gaps = 21/256 (8%)
Query: 960 LQEKYQREQEKLREEWQRAKQEAE-RENSKYLDEELMVLSSNSMSLTTREPSLATWEATW 1018
L+ K + ++ L +E Q +QE + RE + E+ + + +E + E
Sbjct: 37 LKRKLETDKIPLPQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV 96
Query: 1019 SEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQDQLVIERERKWEQQLQEEQEQKR 1077
E +EG +E + + QE V E +G+ + Q+ V E+E + +Q + +EQ+
Sbjct: 97 RE------QEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 150
Query: 1078 LQAEAEEQKRPAEEQKRQAEIE-RETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKS 1136
E E Q R E Q R+ E + RE ++ + V + +E G G +
Sbjct: 151 QVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQV------REQEGQMGEQEGQMGEQ 204
Query: 1137 RSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRKRTPLH 1196
+ + K +Q+G Q R ++EQ+ E ++Q Q ++ +
Sbjct: 205 E-----EQMGEQEEQMQKQEEQMGEQ-EEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMR 258
Query: 1197 NDNSWIRQRSASVNKE 1212
+R++ + ++
Sbjct: 259 KQEEQMREQEEQMREQ 274
Score = 38.5 bits (88), Expect = 0.045
Identities = 25/122 (20%), Positives = 61/122 (50%), Gaps = 3/122 (2%)
Query: 388 EAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQL- 446
E +RE K++ E+ Q E + + E + +R+ + E+M++ + Q+
Sbjct: 269 EQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMRE-QEEQMREQEEQMG 327
Query: 447 KEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQ 506
K+++Q W+ W+ + + + + ++ E+ E+++KQ + K+ + K+ Q R+ +
Sbjct: 328 KQEEQMWEQKEQMWEQKEQMWKQE-EQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQE 386
Query: 507 NQ 508
Q
Sbjct: 387 EQ 388
Score = 36.2 bits (82), Expect = 0.22
Identities = 34/215 (15%), Positives = 96/215 (44%), Gaps = 12/215 (5%)
Query: 392 EASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQ 451
+ ++R ++ M E+ Q E + + + + +R+ + ++ + LK+++Q
Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQKQEEQMRKQEEQMREQEEQMREQEEQMLKQKEQ 284
Query: 452 KWQDD-LAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKS 510
Q++ + +++ + +++++E+ E E+Q E+ ++ K ++M + +E ++
Sbjct: 285 TEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGKQEEQMWEQKEQMWEQ- 343
Query: 511 TVPSRRRMYSFDDVL---EEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAK 567
+ +M+ ++ + EE + V + Q + EE+ ++ K++ +
Sbjct: 344 ----KEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEEQMGEQ 399
Query: 568 REDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 602
+E + Q+ Q EEQ +R + M
Sbjct: 400 KEQMGEQKEQMREQ---EEQMGEQKEQMRKQEEHM 431
Score = 36.2 bits (82), Expect = 0.22
Identities = 35/189 (18%), Positives = 88/189 (46%), Gaps = 15/189 (7%)
Query: 385 KRWEAIRE-ASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIK 443
K+ E +RE ++R ++ M+++ Q E + + ++ Q Q E+M++ +
Sbjct: 259 KQEEQMREQEEQMREQEEQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQ--EEQMREQE 316
Query: 444 SQLKEQDQ---KWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEML 500
Q++EQ++ K ++ + + K++ + K++E+ E E+Q ++K + + +E +
Sbjct: 317 EQMREQEEQMGKQEEQMWEQKEQMWEQKEQMWKQEEQMGEQEEQ-MQKQEEQVRKQEEQM 375
Query: 501 QDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKE 560
+ +E Q +K R++ + E+ + E Q EE+ ++ K+
Sbjct: 376 RKQEEQMRKQEEQMRKQEEQMGEQKEQ--------MGEQKEQMREQEEQMGEQKEQMRKQ 427
Query: 561 DSTTFAKRE 569
+ ++E
Sbjct: 428 EEHMGEQKE 436
Score = 35.8 bits (81), Expect = 0.29
Identities = 40/144 (27%), Positives = 67/144 (46%), Gaps = 15/144 (10%)
Query: 977 RAKQEAERENSKYLDEELMVLSSNSMSLTTR----EPSLATWEATWSEGSKSSDREGTRA 1032
R E +E + L EEL ++ + + + L T + + + ++EG
Sbjct: 3 RITNEELKEKNAELQEELQLVETEKSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQVR 62
Query: 1033 GEEERRQPQEEVVHEDQGK-KPQDQLVIERE---RKWEQQLQEEQEQKRLQA----EAEE 1084
+E + + QE V E +G+ + Q+ V E+E R+ E Q++E++ Q R Q E E
Sbjct: 63 EQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEG 122
Query: 1085 QKRPAEEQKRQAE---IERETSVR 1105
Q R E Q R+ E E+E VR
Sbjct: 123 QVREQEGQVREQEGQVREQEGQVR 146
Score = 35.4 bits (80), Expect = 0.38
Identities = 42/159 (26%), Positives = 74/159 (46%), Gaps = 12/159 (7%)
Query: 958 RLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEAT 1017
R+ E+ + + +L+EE Q + E + E ++ E L ++ + L
Sbjct: 3 RITNEELKEKNAELQEELQLVETE-KSEIQLHIKELKRKLETDKIPLPQEGQVREQEGQV 61
Query: 1018 WSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQDQLVIERE---RKWEQQLQEEQ 1073
+ + ++EG +E + + QE V E +G+ + Q+ V E+E R+ E Q++E++
Sbjct: 62 REQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVREQE 121
Query: 1074 EQKRLQA----EAEEQKRPAEEQKRQAE---IERETSVR 1105
Q R Q E E Q R E Q R+ E E+E VR
Sbjct: 122 GQVREQEGQVREQEGQVREQEGQVREQEGQVREQEGQVR 160
Score = 31.6 bits (70), Expect = 5.5
Identities = 24/132 (18%), Positives = 65/132 (49%), Gaps = 4/132 (3%)
Query: 381 EADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQ 440
E LK+ E + + ++ M E+ Q E + + E + + + + E+M
Sbjct: 276 EQMLKQKEQTEQEEQTGEQEEQMREQEEQMREQEEQMREQEEQMREQEEQMGK-QEEQMW 334
Query: 441 KIKSQLKEQ-DQKW--QDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFK 497
+ K Q+ EQ +Q W ++ + + +++ + ++K++E+ + E+Q ++ ++ K +
Sbjct: 335 EQKEQMWEQKEQMWKQEEQMGEQEEQMQKQEEQVRKQEEQMRKQEEQMRKQEEQMRKQEE 394
Query: 498 EMLQDRESQNQK 509
+M + +E ++
Sbjct: 395 QMGEQKEQMGEQ 406
Score = 30.8 bits (68), Expect = 9.4
Identities = 36/174 (20%), Positives = 75/174 (43%), Gaps = 16/174 (9%)
Query: 433 QLRYEEMQ--KIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSK 490
Q+R +E Q + + Q++EQ+ + ++ + ++ ++ E+ E+++KQ + +
Sbjct: 165 QVREQEGQVREQEGQVREQEGQVREQEGQMGEQEGQMGEQEEQMGEQEEQMQKQEEQMGE 224
Query: 491 RSSKTFK--EMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEE 548
+ + K E + ++E Q QK +++ EE R + E Q EE
Sbjct: 225 QEEQMRKQEEQMGEQEEQVQKQEEQVQKQ--------EEQMRKQEEQMREQEEQMREQEE 276
Query: 549 KGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 602
+ + +E+ T + + R E Q+ Q EEQ +R + QM
Sbjct: 277 QMLKQKEQTEQEEQTGEQEEQMREQEE-QMREQ---EEQMREQEEQMREQEEQM 326
>gi|44680105 caldesmon 1 isoform 1 [Homo sapiens]
Length = 793
Score = 69.3 bits (168), Expect = 2e-11
Identities = 80/340 (23%), Positives = 142/340 (41%), Gaps = 39/340 (11%)
Query: 783 VASVEAGSPAEFSQLQVDDEIIAINN-TKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGK 841
V EA + +Q++ DDE + + K +EA+ + +E + D
Sbjct: 74 VPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFDPTITDA----S 129
Query: 842 AGSPETKWIDATSGIYNSEKSSNLSVTTDFSESLQSSNI-ESKEINGIHD-ESNAFESKA 899
P + + T+ +EK + E ++ + +S + N D E N E K
Sbjct: 130 LSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETVTKSYQKNDWRDAEENKKEDKE 189
Query: 900 SESISLKNLKRRS-----------QFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKR 948
E + KR S + + ++VV L IS+ EE K+
Sbjct: 190 KEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSLKNGQISS---------EEPKQ 240
Query: 949 QERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAE-------RENSKYLDEELMVLSSNS 1001
+E ++ D + + E++K R E +RA+ EAE ++ K DE + +
Sbjct: 241 EEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKIADERARIEAEEK 300
Query: 1002 MSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIER 1061
+ RE A E K + E R EEE+R +E +++ K+ + ER
Sbjct: 301 AAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAE----ER 356
Query: 1062 ERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERE 1101
+R E++ + +E++R +AE EE+K EEQKR ++E +
Sbjct: 357 QRIKEEEKRAAEERQRARAE-EEEKAKVEEQKRNKQLEEK 395
Score = 54.7 bits (130), Expect = 6e-07
Identities = 147/755 (19%), Positives = 285/755 (37%), Gaps = 99/755 (13%)
Query: 455 DDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPS 514
DD + ++ R+ QK++E R E E+ A + R+ +E ++R + ++ +
Sbjct: 2 DDFERRRELRR------QKREEMRLEAERIAYQ---RNDDDEEEAARERRRRARQERLRQ 52
Query: 515 RRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTT 574
++ S V ++ + +V + E K T +++ +D F +R R
Sbjct: 53 KQEEESLGQVTDQVEVNAQNSVPDE-------EAKTTTTNTQVEGDDEAAFLERLARR-- 103
Query: 575 EIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPRPFGS 634
EE+ L R + + T ASL R+ + T + S
Sbjct: 104 ----------EERRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKS 153
Query: 635 QTRG-------ISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSS 687
++R ++ +SY +D W+ D E+ K+ P +
Sbjct: 154 ESRQERYEIEETETVTKSYQKND-WR---DAEENKKEDKEKEEEEEEKPKRGSIG----- 204
Query: 688 QKEVAATEEDVTRLPSPTSPFSSLSQDQAATS--KATLSSTSGLDLMS--ESGEGEISPQ 743
+ +V E+ T + SL Q ++ K G D +S E E E +
Sbjct: 205 ENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKER 264
Query: 744 REVSRSQDQFSDMRISINQTPGKSLDFGFTIKWDIPGIFVASV------------EAGSP 791
E R++ + + + K D I+ + E
Sbjct: 265 AEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKRA 324
Query: 792 AEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLVMDVRRYGKAGSPETKWID 851
AE Q ++E A + + K E + +E + R+ +A E ++
Sbjct: 325 AEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVE 384
Query: 852 ATSGIYNSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRR 911
E+ + T IE K +N E A E K ++ LK++
Sbjct: 385 EQKRNKQLEEKKHAMQETKIKGEKVEQKIEGKWVN----EKKAQEDKLQTAV----LKKQ 436
Query: 912 SQFFEQGSSDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKL 971
+ E+G+ + A + + + K++E + +++ ++K +E+ K
Sbjct: 437 GE--EKGTK-----------VQAKREKLQEDKPTFKKEEI---KDEKIKKDKEPKEEVKS 480
Query: 972 REEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTR 1031
+ ++ E + +N +++ +L + N+ S S+ T EA EG+ + G R
Sbjct: 481 FMDRKKGFTEVKSQNGEFMTHKLKH-TENTFSRPGGRASVDTKEA---EGAPQVEA-GKR 535
Query: 1032 AGEEERRQPQEEVVHEDQGKKPQDQLVIERE-----RKWEQQLQEEQEQKRLQAEAEEQK 1086
E RR+ + E ++ K+ Q + +E E R+ +++ EE+EQ+R Q EA+ +
Sbjct: 536 LEELRRRRGETESEEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKL 595
Query: 1087 RPAEEQKR-QAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLP-GDRNKSRSTTELDD 1144
R EE++R + EIER + + R+ + + ++ F P G K E +
Sbjct: 596 REEEEKRRLKEEIERRRA-EAAEKRQKMPEDGLSDDKKPFKCFTPKGSSLKIEERAEFLN 654
Query: 1145 YSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAE 1179
S K+ K Q + S+ S+ EQ S E
Sbjct: 655 KSVQKSSGVKSTHQAAIV--SKIDSRLEQYTSAIE 687
Score = 48.9 bits (115), Expect = 3e-05
Identities = 68/305 (22%), Positives = 122/305 (40%), Gaps = 52/305 (17%)
Query: 941 DQEEERKRQERWQKEQDRLLQEK--YQR----EQEKLREEWQRAKQE--AERENSKYLDE 992
D E R+ R ++E+ RL E+ YQR E+E RE +RA+QE +++ + L +
Sbjct: 2 DDFERRRELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQ 61
Query: 993 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1052
+ N+ + E + T T EG + A EERRQ K+
Sbjct: 62 VTDQVEVNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQ-----------KR 110
Query: 1053 PQDQLVIERERKWEQQLQEEQ---EQKRLQAEAEEQKRPAEEQKRQAEIER------ETS 1103
Q+ L ER+++++ + + +R+Q + E + +E+K ++ ER ET
Sbjct: 111 LQEAL--ERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETETV 168
Query: 1104 VRIYQYRRPVDS-----YDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQ 1158
+ YQ D+ D K EE G +++ +++ +T +
Sbjct: 169 TKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVVMSL 228
Query: 1159 IGNMTSSQRRSKKEQVPSG-----------------AELERQQILQEMRKRTPLHNDNSW 1201
SS+ ++E+ G AE ER ++ E R+R D
Sbjct: 229 KNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQDKKI 288
Query: 1202 IRQRS 1206
+R+
Sbjct: 289 ADERA 293
Score = 47.8 bits (112), Expect = 7e-05
Identities = 57/262 (21%), Positives = 111/262 (42%), Gaps = 22/262 (8%)
Query: 944 EERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMS 1003
+ER R E +K + + + E+E++REE +RA +E +R + EE +
Sbjct: 290 DERARIEAEEKAAAQERERREAEERERMREEEKRAAEERQR-----IKEEEKRAAEERQR 344
Query: 1004 LTTREPSLATWEATWSEGSKSSDREGTRAGEEE----------RRQPQEEVVHEDQGKKP 1053
+ E A E K + E RA EE R + EE H Q K
Sbjct: 345 IKEEEKRAAEERQRIKEEEKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKI 404
Query: 1054 QDQLVIER-ERKW--EQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYR 1110
+ + V ++ E KW E++ QE++ Q + + E+K + KR+ E + + + + +
Sbjct: 405 KGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQGEEKGTKVQAKREKLQEDKPTFKKEEIK 464
Query: 1111 RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSK 1170
D EE S F+ + + ++ ++ T+K K+ + + +
Sbjct: 465 DEKIKKDKEPKEEVKS-FMDRKKGFTEVKSQNGEFMTHK---LKHTENTFSRPGGRASVD 520
Query: 1171 KEQVPSGAELERQQILQEMRKR 1192
++ ++E + L+E+R+R
Sbjct: 521 TKEAEGAPQVEAGKRLEELRRR 542
Score = 44.7 bits (104), Expect = 6e-04
Identities = 63/282 (22%), Positives = 128/282 (45%), Gaps = 18/282 (6%)
Query: 942 QEEERKRQERWQ-KEQDRLLQEKYQR---EQEKLREEWQRAKQEA-----ERENSKYLDE 992
+EE+R +ER + KE+++ E+ QR E+++ EE QR K+E ER+ ++ +E
Sbjct: 319 EEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARAEEE 378
Query: 993 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDR-EGTRAGEEERRQPQ-EEVVHEDQG 1050
E + + E A E T +G K + EG E++ ++ + + V + QG
Sbjct: 379 EKAKVEEQKRNKQLEEKKHAMQE-TKIKGEKVEQKIEGKWVNEKKAQEDKLQTAVLKKQG 437
Query: 1051 KKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYR 1110
++ ++ +RE+ E + ++E+ + + ++ K P EE K + ++ +
Sbjct: 438 EEKGTKVQAKREKLQEDKPTFKKEEIK-DEKIKKDKEPKEEVKSFMD-RKKGFTEVKSQN 495
Query: 1111 RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNN-KYLDQIGNMTSSQRRS 1169
++ + TE S PG R S T E + + G + L + T S+
Sbjct: 496 GEFMTHKLKHTENTFS--RPGGR-ASVDTKEAEGAPQVEAGKRLEELRRRRGETESEEFE 552
Query: 1170 KKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNK 1211
K +Q A LE +++ ++ +R + + R++ + K
Sbjct: 553 KLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRK 594
Score = 35.8 bits (81), Expect = 0.29
Identities = 34/181 (18%), Positives = 80/181 (44%), Gaps = 6/181 (3%)
Query: 397 RHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDD 456
R +KRL QK + + + + + +QN ++ KS+ +++ + ++
Sbjct: 106 RRQKRLQEALERQKEFDPTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEET 165
Query: 457 LAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS---KTFKEMLQDRESQNQKSTVP 513
K +K+ D ++ K+E +E E++ EK KR S + M++++ +++Q+ TV
Sbjct: 166 ETVTKSYQKNDWRDAEENKKEDKEKEEEEEEKPKRGSIGENQVEVMVEEKTTESQEETVV 225
Query: 514 ---SRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKRED 570
++ S + EE + + +S E +E+ + + E+ +D
Sbjct: 226 MSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKERAEAERARLEAEERERIKAEQD 285
Query: 571 R 571
+
Sbjct: 286 K 286
Score = 34.3 bits (77), Expect = 0.85
Identities = 40/181 (22%), Positives = 80/181 (44%), Gaps = 39/181 (21%)
Query: 381 EADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQ 440
E D +R EA R ++R+ E+ K ++D A R E +
Sbjct: 259 EEDKERAEAERARLEAEERERIKAEQ----------DKKIADERA---------RIEAEE 299
Query: 441 KIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER--------EEIEKQALEKSKRS 492
K +Q +E+ + + + + +++R + K++E+R +E EK+A E+ +R
Sbjct: 300 KAAAQERERREAEERERMREEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRI 359
Query: 493 SKTFKEMLQDRE----SQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEE 548
+ K ++R+ + +K+ V ++R + LEE K + E + E+VE+
Sbjct: 360 KEEEKRAAEERQRARAEEEEKAKVEEQKR----NKQLEEKKH----AMQETKIKGEKVEQ 411
Query: 549 K 549
K
Sbjct: 412 K 412
Score = 33.5 bits (75), Expect = 1.5
Identities = 27/123 (21%), Positives = 59/123 (47%), Gaps = 12/123 (9%)
Query: 437 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF 496
EE +K+K + +E + ++ K ++RRK + Q++K+E + + + E+ +R
Sbjct: 549 EEFEKLKQKQQEAALELEELKKKREERRKVLEEEEQRRKQEEADRKLREEEEKRR----L 604
Query: 497 KEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSE 556
KE ++ R ++ + +R +D L + K+P + S S ++EE+
Sbjct: 605 KEEIERRRAE------AAEKRQKMPEDGLSDDKKPFKCFTPKGS--SLKIEERAEFLNKS 656
Query: 557 IPK 559
+ K
Sbjct: 657 VQK 659
Score = 33.1 bits (74), Expect = 1.9
Identities = 40/202 (19%), Positives = 84/202 (41%), Gaps = 17/202 (8%)
Query: 413 GENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQ 472
GEN + M + + Q + + +I S+ +Q+++ + + K D +
Sbjct: 204 GENQVEVMVEEKTTESQEETVVMSLKNGQISSEEPKQEEEREQGSDEISHHEKMEEEDKE 263
Query: 473 KKKEEREEIEKQALE--KSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKR 530
+ + ER +E + E K+++ K E + + + RR + + EE KR
Sbjct: 264 RAEAERARLEAEERERIKAEQDKKIADERARIEAEEKAAAQERERREAEERERMREEEKR 323
Query: 531 PPTMTVSEASYQSERV--EEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQ----SPV 584
A+ + +R+ EEK A + KE+ A+ R+ E + ++ +
Sbjct: 324 --------AAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRIKEEEKRAAEERQRARA 375
Query: 585 EEQSPASLSSLRSRSTQMESTR 606
EE+ A + + R+ Q+E +
Sbjct: 376 EEEEKAKVEE-QKRNKQLEEKK 396
Score = 32.7 bits (73), Expect = 2.5
Identities = 39/168 (23%), Positives = 71/168 (42%), Gaps = 30/168 (17%)
Query: 429 QNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER------EEIE 482
+ LR+ + EEM+ ++ Q ++ A + RR++ L++K+EE +++E
Sbjct: 8 RELRRQKREEMRLEAERIAYQRNDDDEEEAARERRRRARQERLRQKQEEESLGQVTDQVE 67
Query: 483 KQAL-----EKSKRSS----------KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEE 527
A E++K ++ F E L RE + QK + R FD
Sbjct: 68 VNAQNSVPDEEAKTTTTNTQVEGDDEAAFLERLARREERRQKRLQEALERQKEFD----- 122
Query: 528 GKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTE 575
PT+T + S S R++ A + +E S + +R + TE
Sbjct: 123 ----PTITDASLSLPSRRMQNDTAENETTEKEEKSESRQERYEIEETE 166
Score = 32.3 bits (72), Expect = 3.2
Identities = 37/171 (21%), Positives = 73/171 (42%), Gaps = 29/171 (16%)
Query: 433 QLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRS 492
+L EE ++IK+ EQD+K D+ A+ + K+ +ERE E + E+ +
Sbjct: 271 RLEAEERERIKA---EQDKKIADERARIEAEEKAAA-------QERERREAEERERMREE 320
Query: 493 SKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGAT 552
K E Q R + +K R+R + EE KR A+ + +R++E+
Sbjct: 321 EKRAAEERQ-RIKEEEKRAAEERQR------IKEEEKR--------AAEERQRIKEE--- 362
Query: 553 YPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQME 603
+E A+ E++ E Q ++ E++ + ++ + +
Sbjct: 363 -EKRAAEERQRARAEEEEKAKVEEQKRNKQLEEKKHAMQETKIKGEKVEQK 412
Score = 32.3 bits (72), Expect = 3.2
Identities = 49/279 (17%), Positives = 113/279 (40%), Gaps = 24/279 (8%)
Query: 428 VQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALE 487
++ LR+ R E + +LK++ Q+ +L +L+KK+EER ++ ++ E
Sbjct: 536 LEELRRRRGETESEEFEKLKQKQQEAALEL-----------EELKKKREERRKVLEEE-E 583
Query: 488 KSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVE 547
+ ++ + +++ ++ E + K + RR + E+ ++ P +S+ +
Sbjct: 584 QRRKQEEADRKLREEEEKRRLKEEIERRRA-----EAAEKRQKMPEDGLSDDKKPFKCFT 638
Query: 548 EKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRV 607
KG++ E E ++ V + Q S ++ + S++ + +
Sbjct: 639 PKGSSLKIEERAEFLNKSVQKSSGVKSTHQAAIVSKIDSRLEQYTSAIEGTKSAKPTKPA 698
Query: 608 SASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVED-IKRTPN 666
++ LP ++ + F S T + P T + + + + +TP+
Sbjct: 699 ASDLPVPAEGVRNIK-SMWEKGNVFSSPT--AAGTPNKETAGLKVGVSSRINEWLTKTPD 755
Query: 667 NVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPT 705
+P+P S L S K ++ V ++ SPT
Sbjct: 756 ---GNKSPAPKPSDLRPGDVSSKRNLWEKQSVDKVTSPT 791
>gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like
protein 6 [Homo sapiens]
Length = 724
Score = 67.4 bits (163), Expect = 9e-11
Identities = 48/192 (25%), Positives = 96/192 (50%), Gaps = 14/192 (7%)
Query: 939 VWDQEEE-RKRQERW--------QKEQDRLLQEKYQREQEKLREEWQRAKQEAE---REN 986
+W QEE+ R+++E W Q+E+ R +EK R++EK+ ++ ++ +++ E R+
Sbjct: 525 MWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQE 584
Query: 987 SKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVH 1046
K ++E + E + E + K ++E +EE+ + QEE +
Sbjct: 585 EKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIR 644
Query: 1047 EDQGK-KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQ-KRQAEIERETSV 1104
E + K + Q++ + E+E ++Q ++ EQ+ E EE+ + EE+ +RQ E E V
Sbjct: 645 EQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEV 704
Query: 1105 RIYQYRRPVDSY 1116
R+ Q + +
Sbjct: 705 RLRQQEEKMQEH 716
Score = 66.6 bits (161), Expect = 2e-10
Identities = 67/322 (20%), Positives = 131/322 (40%), Gaps = 47/322 (14%)
Query: 939 VWDQEEERKRQER--WQKEQD-RLL------QEKYQREQEKLREEWQRAKQEAERENSKY 989
+W++EE+ +RQE W+KE+ R L QEK + ++EK +EE E RE K
Sbjct: 419 MWEKEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEE------EKIREQEKR 472
Query: 990 LDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ 1049
++E + E E W + K ++E R EEE+RQ QEE+
Sbjct: 473 QEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIR--EEEKRQEQEEMWR--- 527
Query: 1050 GKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQY 1109
Q++ + E+E W Q+ + +++++++ + E+ R E+ Q E RE ++++
Sbjct: 528 ----QEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQ 583
Query: 1110 RRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNG--NNKYLDQIGNMTSSQR 1167
+ + E+ K R E+ K G K +Q M +
Sbjct: 584 EEKIREQEEKIREQ---------EEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEE 634
Query: 1168 RSKKEQVPSGAE----LERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRG 1223
+ ++++ + E+++ ++E + + W ++ +E +
Sbjct: 635 KMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQ-------- 686
Query: 1224 ESLDNLDSPRSNSWRQPPWLNQ 1245
E + + W Q L Q
Sbjct: 687 EQEEKMRRQEEKMWEQEVRLRQ 708
Score = 63.2 bits (152), Expect = 2e-09
Identities = 57/247 (23%), Positives = 122/247 (49%), Gaps = 29/247 (11%)
Query: 881 ESKEING-IHDESNAFESKASE-SISLKNLKRRSQFFE--------QGSSDSVVPDLPVP 930
E KE N + ++ ES+ SE +++K LKR+ + + Q +D + +L
Sbjct: 279 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 338
Query: 931 TISAPSRW----VWDQEEERKRQERW-QKEQDRLLQEKYQREQEKLREEWQRAKQEAE-- 983
+ ++ +W++ +++ ++ W Q+E+ + +EK Q ++EK+RE+ ++ +++ E
Sbjct: 339 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 398
Query: 984 -RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE 1042
R+ ++E + M E E W + K + E + E+E+ + QE
Sbjct: 399 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKIRELE-EKMHEQEKIREQE 457
Query: 1043 EVVHEDQGKKPQDQLVIERERKW--EQQLQEEQEQKRLQAE--------AEEQKRPAEEQ 1092
E E++ + Q++ + + W E++++E++E+ R Q E EQ++ EE+
Sbjct: 458 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWRQEEKIHEQEKIREEE 517
Query: 1093 KRQAEIE 1099
KRQ + E
Sbjct: 518 KRQEQEE 524
Score = 60.5 bits (145), Expect = 1e-08
Identities = 42/170 (24%), Positives = 87/170 (51%), Gaps = 8/170 (4%)
Query: 939 VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAE--RENSKYLDEELMV 996
+W QEE+ QE +EQ+ EK R++EK+RE+ ++ +++ E RE + E+
Sbjct: 559 MWRQEEKMHDQEEKIREQE----EKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEK 614
Query: 997 LSSNSMSLTTREPSLATWEATWS-EGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK-PQ 1054
+ + +E + E + K ++E +EE+ + QEE++ E + K Q
Sbjct: 615 MGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQ 674
Query: 1055 DQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSV 1104
++ + E+E K ++Q ++ + Q+ E E + R EE+ ++ + E ++
Sbjct: 675 EEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 724
Score = 48.5 bits (114), Expect = 4e-05
Identities = 53/267 (19%), Positives = 119/267 (44%), Gaps = 21/267 (7%)
Query: 959 LLQEKYQREQEKLREEWQR--AKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEA 1016
L Q++ Q E + L +E Q AK +A+ E ++ + + + +E + WE
Sbjct: 319 LPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR---LNQQQEEKMWRQEEKIQEWEE 375
Query: 1017 TWSEGS-KSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQDQLVIERERK--------WE 1066
E K ++E +EE+ + QEE++ E + K + Q++++ E+E K WE
Sbjct: 376 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWE 435
Query: 1067 QQLQ----EEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTE 1122
++ + EE+ ++ + +E+KR EE+ R+ E +E ++++ + + E
Sbjct: 436 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE 495
Query: 1123 EASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELER 1182
+ + ++ + ++ + + ++I R +KE++ E R
Sbjct: 496 QEEKMWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR--QKEKIHEQEEKIR 553
Query: 1183 QQILQEMRKRTPLHNDNSWIRQRSASV 1209
+Q + R+ +H+ IR++ V
Sbjct: 554 KQEEKMWRQEEKMHDQEEKIREQEEKV 580
Score = 36.2 bits (82), Expect = 0.22
Identities = 50/256 (19%), Positives = 109/256 (42%), Gaps = 23/256 (8%)
Query: 335 KEKSNSCRILVPSYR-QKKDDMLTRKIQSW--KLGTTVPPISFTPGPCSEADLKRW---E 388
K K ++L+P + Q + D L +++QS KL V + + K W E
Sbjct: 309 KRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE 368
Query: 389 AIREASRLRHKKRLMVERLFQKIYG-ENGSKSMSDVSAEDVQNLRQLRYEEM--QKIKSQ 445
I+E ++ + +KI E + ++ E + +R R EEM +K +
Sbjct: 369 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR--RQEEMMWEKEEKM 426
Query: 446 LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRES 505
++++ W+ + + K + + +++EE+ + E++ E+ KR + K Q+ +
Sbjct: 427 RRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 486
Query: 506 QNQKSTVPSR--------RRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATY-PSE 556
+ Q+ + + +++ + + EE KR E Q E++ E+ + E
Sbjct: 487 REQEEKIREQEEKMWRQEEKIHEQEKIREEEKR---QEQEEMWRQEEKIREQEEIWRQKE 543
Query: 557 IPKEDSTTFAKREDRV 572
E K+E+++
Sbjct: 544 KIHEQEEKIRKQEEKM 559
Score = 33.5 bits (75), Expect = 1.5
Identities = 26/138 (18%), Positives = 63/138 (45%), Gaps = 5/138 (3%)
Query: 385 KRWEAIREASRLRHKKRLMVERLF---QKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQK 441
K W + K R E+++ +KI + + + + + Q + E+M +
Sbjct: 558 KMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGE 617
Query: 442 IKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTF--KEM 499
+ ++ EQ++K Q+ K + + + +K +E+ E+I +Q ++ K + +E
Sbjct: 618 QEEKMCEQEEKMQEQEEKMRRQEEKIREQEKKIREQEEKIREQEEMMQEQEEKMWEQEEK 677
Query: 500 LQDRESQNQKSTVPSRRR 517
+ ++E + Q+ RR+
Sbjct: 678 MCEQEEKMQEQEEKMRRQ 695
Score = 31.2 bits (69), Expect = 7.2
Identities = 35/232 (15%), Positives = 97/232 (41%), Gaps = 26/232 (11%)
Query: 387 WEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQL--RYEEMQKIKS 444
WE + ++R ++ +M E+ E + ++ E + +R+L + E +KI+
Sbjct: 406 WE---KEEKMRRQEEMMWEK-------EEKMRRQEEMMWEKEEKIRELEEKMHEQEKIRE 455
Query: 445 Q---------LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKT 495
Q ++EQ+++ + + W+ K + +K +E+ E++ +Q + ++
Sbjct: 456 QEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE-EKIREQEEKMWRQEEKIHEQEKIR 514
Query: 496 FKEMLQDRESQ-NQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERV---EEKGA 551
+E Q++E Q+ + + ++ + + E + + Q E++ EEK
Sbjct: 515 EEEKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIR 574
Query: 552 TYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQME 603
++ +++ + E E ++ Q + ++ + + + E
Sbjct: 575 EQEEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQE 626
>gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo
sapiens]
Length = 668
Score = 67.0 bits (162), Expect = 1e-10
Identities = 52/176 (29%), Positives = 86/176 (48%), Gaps = 18/176 (10%)
Query: 941 DQEEERKRQER--WQKEQDRLLQEKYQREQEKLREEWQRAKQEAE-RENSKYLDEELMVL 997
+QEE+ + QE+ W+ QE+ EQEK+REE +R +QE R+ K ++E +
Sbjct: 427 EQEEKIREQEKKMWR-------QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWR 479
Query: 998 SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQL 1057
M +E E W + K D+E +EE+ QEE + E Q++
Sbjct: 480 QKEKMH--EQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIRE------QEEK 531
Query: 1058 VIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPV 1113
+ E+E K +Q + QEQ+ E EE+ + E+ +RQ E RE +I + + +
Sbjct: 532 IREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKI 587
Score = 65.9 bits (159), Expect = 3e-10
Identities = 51/182 (28%), Positives = 95/182 (52%), Gaps = 15/182 (8%)
Query: 939 VWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQ-EAERENSKYLDEELMVL 997
+W QEE+ QE+ ++E+ R QE+ R++EK+RE+ + +Q E E K +E V
Sbjct: 439 MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVW 498
Query: 998 SSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHE------DQGK 1051
E E W + K ++E +EE+ + QEE++ E +Q +
Sbjct: 499 RQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEE 558
Query: 1052 KPQDQLVIERERKWEQQLQEEQEQKRLQAE---AEEQKRPAEEQK--RQAEIERETSVRI 1106
K Q+Q E+ R+ E++++E++E+ R Q E +E+K +E+K Q E+ +E ++
Sbjct: 559 KMQEQ---EKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKM 615
Query: 1107 YQ 1108
++
Sbjct: 616 WE 617
Score = 65.9 bits (159), Expect = 3e-10
Identities = 45/184 (24%), Positives = 94/184 (51%), Gaps = 6/184 (3%)
Query: 939 VWDQEEERKRQERWQKEQDRLL--QEKYQREQEKLREEWQR--AKQEAERENSKYLDEEL 994
+W Q+E+ QE+ +K+++++ +EK ++EK+RE+ ++ ++E RE + + E+
Sbjct: 477 IWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQE 536
Query: 995 MVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KP 1053
+ + +E + E E K +E +EE+ + Q+E + E + K
Sbjct: 537 EKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWE 596
Query: 1054 QDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQ-KRQAEIERETSVRIYQYRRP 1112
Q++ + E+E ++Q ++ EQ+ E EE+ + EE+ +RQ E E VR+ Q
Sbjct: 597 QEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEK 656
Query: 1113 VDSY 1116
+ +
Sbjct: 657 MQEH 660
Score = 62.4 bits (150), Expect = 3e-09
Identities = 57/247 (23%), Positives = 120/247 (48%), Gaps = 29/247 (11%)
Query: 881 ESKEING-IHDESNAFESKASE-SISLKNLKRRSQFFE--------QGSSDSVVPDLPVP 930
E KE N + ++ ES+ SE +++K LKR+ + + Q +D + +L
Sbjct: 218 ELKEKNAKLQEKLQLVESEKSEIQLNVKELKRKLERAKLLLPQQQLQAEADHLGKELQSV 277
Query: 931 TISAPSRW----VWDQEEERKRQERW-QKEQDRLLQEKYQREQEKLREEWQRAKQEAE-- 983
+ ++ +W++ +++ ++ W Q+E+ + +EK Q ++EK+RE+ ++ +++ E
Sbjct: 278 SAKLQAQVEENELWNRLNQQQEEKMWRQEEKIQEWEEKIQEQEEKIREQEEKIREQEEKM 337
Query: 984 -RENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE 1042
R+ ++E + M E E W + K + E + E+E+ + QE
Sbjct: 338 RRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKEEKIRELE-EKMHEQEKIREQE 396
Query: 1043 EVVHEDQGKKPQDQLVIERERKWEQQLQ-EEQEQK---------RLQAEAEEQKRPAEEQ 1092
E E++ + Q++ + + W Q+ + EQE+K R + + EQ++ EE+
Sbjct: 397 EKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWRQEEKIHEQEKIREEE 456
Query: 1093 KRQAEIE 1099
KRQ + E
Sbjct: 457 KRQEQEE 463
Score = 62.0 bits (149), Expect = 4e-09
Identities = 42/164 (25%), Positives = 87/164 (53%), Gaps = 6/164 (3%)
Query: 939 VWDQEEE-RKRQERWQKEQDRLLQEKYQREQEKL--REEWQRAKQEAERENSKYLDEELM 995
+W QEE+ R+++E W++++ QEK ++++EK+ +EE ++E RE + + +
Sbjct: 464 MWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEE 523
Query: 996 VLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQ 1054
+ + +E + E E + + + E+E+ + QEE + E + K + Q
Sbjct: 524 KIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQ 583
Query: 1055 DQLVIERERK-WEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAE 1097
+ + E+E K WEQ+ ++ +EQ+ + E EE+ EE+ + E
Sbjct: 584 KEKIREQEEKIWEQE-EKIREQEEMMQEQEEKMWEQEEKMCEQE 626
Score = 59.7 bits (143), Expect = 2e-08
Identities = 41/172 (23%), Positives = 87/172 (50%), Gaps = 6/172 (3%)
Query: 939 VWDQEEERKRQERWQKEQDRLL---QEKYQREQEKLREEWQRAKQEAE--RENSKYLDEE 993
VW QEE+ QE +EQ+ + +EK + ++EK+RE+ ++ +++ E +E + + E+
Sbjct: 497 VWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQ 556
Query: 994 LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK- 1052
+ E E + K ++E +EE+ + QEE++ E + K
Sbjct: 557 EEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQEEKMW 616
Query: 1053 PQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSV 1104
Q++ + E+E K ++Q ++ + Q+ E E + R EE+ ++ + E ++
Sbjct: 617 EQEEKMCEQEEKMQEQEEKMRRQEEKMWEQEVRLRQQEEKMQEHQEHLEAAI 668
Score = 58.5 bits (140), Expect = 4e-08
Identities = 66/283 (23%), Positives = 126/283 (44%), Gaps = 21/283 (7%)
Query: 942 QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNS 1001
QE+E K +E Q+E+ R +EK +R++E + W++ ++ +E + EE M
Sbjct: 317 QEQEEKIRE--QEEKIREQEEKMRRQEEMM---WEKEEKMRRQEEMMWEKEEKMRRLEEM 371
Query: 1002 MSLTTREPSLATWEATWSEGSKSSDREGTRAGEE-----ERRQPQEEVVHEDQGK-KPQD 1055
M +E + E E K ++E R EE E+RQ QE + + K + Q+
Sbjct: 372 M--WEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQE 429
Query: 1056 QLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDS 1115
+ + E+E+K +Q ++ EQ++++ EE+++ EE RQ E RE Q + +
Sbjct: 430 EKIREQEKKMWRQEEKIHEQEKIR--EEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQ 487
Query: 1116 YDIPKTEE---ASSGFLPGDRNKSRSTTELDDYSTNK--NGNNKYLDQIGNMTSSQRRSK 1170
I K EE + K R E K K +Q + + +
Sbjct: 488 EKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMMQ 547
Query: 1171 KEQVPSGAELERQQILQEMRKR-TPLHNDNSWIRQRSASVNKE 1212
+++ G + E+ Q ++MR++ + IR++ + ++
Sbjct: 548 EQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQ 590
Score = 45.1 bits (105), Expect = 5e-04
Identities = 40/171 (23%), Positives = 84/171 (49%), Gaps = 19/171 (11%)
Query: 959 LLQEKYQREQEKLREEWQR--AKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEA 1016
L Q++ Q E + L +E Q AK +A+ E ++ + + + +E + WE
Sbjct: 258 LPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNR---LNQQQEEKMWRQEEKIQEWEE 314
Query: 1017 TWSEGS-KSSDREGTRAGEEERRQPQEEVVHEDQGK-KPQDQLVIERERK--------WE 1066
E K ++E +EE+ + QEE++ E + K + Q++++ E+E K WE
Sbjct: 315 KIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWE 374
Query: 1067 QQLQ----EEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPV 1113
++ + EE+ ++ + +E+KR EE+ R+ E +E ++++ +
Sbjct: 375 KEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 425
Score = 37.7 bits (86), Expect = 0.077
Identities = 49/255 (19%), Positives = 108/255 (42%), Gaps = 22/255 (8%)
Query: 335 KEKSNSCRILVPSYR-QKKDDMLTRKIQSW--KLGTTVPPISFTPGPCSEADLKRW---E 388
K K ++L+P + Q + D L +++QS KL V + + K W E
Sbjct: 248 KRKLERAKLLLPQQQLQAEADHLGKELQSVSAKLQAQVEENELWNRLNQQQEEKMWRQEE 307
Query: 389 AIREASRLRHKKRLMVERLFQKIYG-ENGSKSMSDVSAEDVQNLRQLRYEEM--QKIKSQ 445
I+E ++ + +KI E + ++ E + +R R EEM +K +
Sbjct: 308 KIQEWEEKIQEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMR--RQEEMMWEKEEKM 365
Query: 446 LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRES 505
+ ++ W+ + + K + + +++EE+ + E++ E+ KR + K Q+ +
Sbjct: 366 RRLEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKI 425
Query: 506 QNQKSTVPSR--------RRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEI 557
+ Q+ + + +++ + + EE KR E Q E++ E+ + +
Sbjct: 426 REQEEKIREQEKKMWRQEEKIHEQEKIREEEKR---QEQEEMWRQEEKIREQEEIWRQKE 482
Query: 558 PKEDSTTFAKREDRV 572
+ K+E++V
Sbjct: 483 KMHEQEKIRKQEEKV 497
Score = 33.1 bits (74), Expect = 1.9
Identities = 29/167 (17%), Positives = 74/167 (44%), Gaps = 17/167 (10%)
Query: 426 EDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEER------- 478
E + ++R EE ++ + ++ Q++K ++ W+ + K + + +K+EE+
Sbjct: 444 EKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEK 503
Query: 479 ----EEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTM 534
EE ++ EK R + +E Q+ + + Q+ + + M + + G++ M
Sbjct: 504 MHDQEEKIREQEEKMWRQEEKIRE--QEEKIREQEEKIREQEEMMQ-EQEEKMGEQEEKM 560
Query: 535 TVSEASYQSE---RVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQL 578
E + E R +E+ E +E ++E+++ + ++
Sbjct: 561 QEQEKMRRQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEM 607
Score = 32.7 bits (73), Expect = 2.5
Identities = 34/225 (15%), Positives = 97/225 (43%), Gaps = 19/225 (8%)
Query: 388 EAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEE-MQKIKSQL 446
E IRE H++ E++ ++ + + + Q + R EE +++ + ++
Sbjct: 377 EKIRELEEKMHEQ----EKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKI 432
Query: 447 KEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSK-RSSKTF---KEMLQD 502
+EQ++K W+ K + + +++E+R+E E+ ++ K R + KE + +
Sbjct: 433 REQEKK------MWRQEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEIWRQKEKMHE 486
Query: 503 RES--QNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERV--EEKGATYPSEIP 558
+E + ++ +M+ ++ + E + + Q E++ +E+ E+
Sbjct: 487 QEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQEEMM 546
Query: 559 KEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQME 603
+E ++E+++ + ++ Q + + + + + E
Sbjct: 547 QEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIREQE 591
Score = 32.0 bits (71), Expect = 4.2
Identities = 23/129 (17%), Positives = 60/129 (46%), Gaps = 6/129 (4%)
Query: 381 EADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQ 440
E + K W + K R E++ ++ E + + E + +++ E+M+
Sbjct: 513 EQEEKMWRQEEKIREQEEKIREQEEKIREQ---EEMMQEQEEKMGEQEEKMQE--QEKMR 567
Query: 441 KIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEML 500
+ + +++EQ++K ++ K +++ + +K +E+ E +++Q EK + E
Sbjct: 568 RQEEKIREQEEKIREQKEKIREQEEKIWEQEEKIREQEEMMQEQE-EKMWEQEEKMCEQE 626
Query: 501 QDRESQNQK 509
+ + Q +K
Sbjct: 627 EKMQEQEEK 635
>gi|116008442 zinc finger CCCH-type containing 13 [Homo sapiens]
Length = 1564
Score = 66.6 bits (161), Expect = 2e-10
Identities = 62/290 (21%), Positives = 131/290 (45%), Gaps = 21/290 (7%)
Query: 933 SAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDE 992
S+P R +E + + R ++ DR+ + +R +E+ RE + ++E ERE + +
Sbjct: 642 SSPIRHQGRNDELERDERREERRVDRVDDRRDERARERDRERERDRERERERERERDRER 701
Query: 993 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEER-RQPQEEVVHEDQGK 1051
E RE E K DRE R + +R R+ + E E + +
Sbjct: 702 E-----------KERELERERAREREREREKERDRERDRDRDHDRERERERERDREKERE 750
Query: 1052 KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPA--EEQKRQAEIERETSVRIYQY 1109
+ +++ ERER+ E++ + E+E++R + +E++R E++ + + RE I +
Sbjct: 751 REREERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIRED 810
Query: 1110 RRPVDSYDIPKTE-----EASSGFLPGDRNKSRSTTELDDYST--NKNGNNKYLDQIGNM 1162
R P D +D K++ E S + + + + D Y++ +KN ++ L Q+
Sbjct: 811 RNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRP 870
Query: 1163 TSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1212
S+ S +++ + RK + + ++++ +SV+K+
Sbjct: 871 QESRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQ 920
Score = 57.8 bits (138), Expect = 7e-08
Identities = 136/744 (18%), Positives = 269/744 (36%), Gaps = 92/744 (12%)
Query: 381 EADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQ 440
E +L+R E RE R R K+R +R + + + + + R+ E +
Sbjct: 704 ERELER-ERAREREREREKER---DRERDRDRDHDRERERERERDREKEREREREERERE 759
Query: 441 KIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKK-------KEEREEIEKQALEKSKRSS 493
+ + + +E++++ + + A+ +D+ + D + K +E+REEI + +
Sbjct: 760 RERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGHDE 819
Query: 494 KTFKEMLQDRESQNQKSTVPSRRRMYSFD-------DVLEEGKRPPTMTV----SEASYQ 542
+ K+ ++ S + + + P RRR +S D D E R + V S +
Sbjct: 820 RKSKKRYRNEGSPSPRQS-PKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSP 878
Query: 543 SERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQM 602
S E++ + E K + ++R + + ++ S EQ+ L S R R+ +
Sbjct: 879 SHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEI-LESSRMRAQDI 937
Query: 603 ESTRVSASLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSY---TMDDAWKYNGDVE 659
S S R D + + + +P + + R T +D ++
Sbjct: 938 IGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSPKKG 997
Query: 660 DIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVT---RLPSPTSPFSSLSQDQA 716
K++ D S ++ S+K+ +T L + + + +D
Sbjct: 998 QKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEELVEMCNGKNGILEDSQ 1057
Query: 717 ATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFGFTIKW 776
S S D+ + E + S + + P + T+
Sbjct: 1058 KKEDTAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPSPLSSLLPPPPPVATATATTVPA 1117
Query: 777 DIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKAQETGHLV--- 833
+ A+ + S + + NNT + + ++ + ET H+
Sbjct: 1118 TLAATTAAAATSFSTSAITISTSATPTNTTNNTFANEDSHRKCHRTRVEKVETPHVTIED 1177
Query: 834 ------MDVRRYGKAGSPETKWIDAT--------------------------SGIYNSEK 861
MD +R GS + + SG + EK
Sbjct: 1178 AQHRKPMDQKRSSSLGSNRSNRSHTSGRLRSPSNDSAHRSGDDQSGRKRVLHSGSRDREK 1237
Query: 862 SSNLSVTTDFSESLQS--SNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGS 919
+ +L +T + + S+ + +S + S+ S S + + RS GS
Sbjct: 1238 TKSLEITGERKSRIDQLKRGEPSRSTSSDRQDSRSHSSRRSSPESDRQVHSRS-----GS 1292
Query: 920 SDSVVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAK 979
DS + R+ D+E ER+R++ Q+E DR + + R ++ R+ + +
Sbjct: 1293 FDSR------DRLQERDRYEHDRERERERRDTRQREWDRDADKDWPRNRD--RDRLRERE 1344
Query: 980 QEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQ 1039
+E ER+ + LD E L S+S+ T+E++ E K E GE ER
Sbjct: 1345 RERERDKRRDLDRERERLISDSVERDRDRDRDRTFESSQIESVKRC--EAKLEGEHER-- 1400
Query: 1040 PQEEVVHEDQGKKPQDQLVIERER 1063
D +D L +++ER
Sbjct: 1401 --------DLESTSRDSLALDKER 1416
Score = 57.4 bits (137), Expect = 9e-08
Identities = 88/419 (21%), Positives = 166/419 (39%), Gaps = 43/419 (10%)
Query: 942 QEEERKRQERWQKEQDRLLQEKYQREQEKLRE---EWQ---------RAKQEAERENSKY 989
+E ER+R+ ++E++R + + RE++K RE +W+ R K+E RE+
Sbjct: 754 EERERERERERERERERERERERARERDKERERQRDWEDKDKGRDDRREKREEIREDRNP 813
Query: 990 LDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQ 1049
D S PS E S SD + + E+ + +VV +
Sbjct: 814 RDGH-DERKSKKRYRNEGSPSPRQSPKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQE 872
Query: 1050 GKK-PQDQLVIERERKW--EQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRI 1106
+ L +R+ +W E + E +E R E E +++ + K++ + E S R+
Sbjct: 873 SRSLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRM 932
Query: 1107 YQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIG-NMTSS 1165
R D ++E+ + D NK ++ + K D +G +
Sbjct: 933 ----RAQDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKE------DDVGIERGNI 982
Query: 1166 QRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMRRGES 1225
+ S+ QV S + ++++ +++ RK++ +D S S K P I + E
Sbjct: 983 ETTSEDGQVFSPKKGQKKKSIEKKRKKSKGDSDISDEEAAQQSKKKRGPRTPPITTKEEL 1042
Query: 1226 LDNLDSPRSNSWRQPPWLNQPTGF--YASSSVQDFSRPPPQLVSTSNRAYMRNP------ 1277
++ + N + + T F ++ V D + ++ + A P
Sbjct: 1043 VEMCNG--KNGILEDSQKKEDTAFSDWSDEDVPDRT----EVTEAEHTATATTPGSTPSP 1096
Query: 1278 -SSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNSVLPVSVTSEALPQE 1335
SS +PPP + T+TT V T + T + + S S S + S P + T+ E
Sbjct: 1097 LSSLLPPPPPVATATATT-VPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANE 1154
Score = 51.2 bits (121), Expect = 7e-06
Identities = 61/309 (19%), Positives = 123/309 (39%), Gaps = 30/309 (9%)
Query: 935 PSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEEL 994
P R DQ + + R + R +E+ QR +R Q E ER+ + +E
Sbjct: 609 PERDNRDQARDSSFERRHGERDRRDNRERDQRPSSPIRH--QGRNDELERDERR--EERR 664
Query: 995 MVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQ 1054
+ + RE E + +RE R E +R + +E + ++ ++ +
Sbjct: 665 VDRVDDRRDERARERD--------RERERDRERERERERERDREREKERELERERARERE 716
Query: 1055 DQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVD 1114
+ ER+R+ ++ ++E++R + E++R E ++R+ E ERE + R
Sbjct: 717 REREKERDRERDRDRDHDRERERERERDREKEREREREERERERERERERERERERERER 776
Query: 1115 SYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQV 1174
+ + K E + D+ + + ++ ++N + + +R+SKK
Sbjct: 777 ARERDKERERQRDWEDKDKGRDDRREKREEIREDRNPRDGH---------DERKSKKRYR 827
Query: 1175 PSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVSLPGIMR----RGESLDNLD 1230
G+ RQ KR H+ +S N++ L ++R R S +L
Sbjct: 828 NEGSPSPRQS-----PKRRREHSPDSDAYNSGDDKNEKHRLLSQVVRPQESRSLSPSHLT 882
Query: 1231 SPRSNSWRQ 1239
R W++
Sbjct: 883 EDRQGRWKE 891
Score = 43.5 bits (101), Expect = 0.001
Identities = 74/380 (19%), Positives = 144/380 (37%), Gaps = 47/380 (12%)
Query: 373 SFTPGPCSEADLKRW-EAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDV-------- 423
S +P +E RW E R+ R +R + L +K+ + + +++
Sbjct: 875 SLSPSHLTEDRQGRWKEEDRKPERKESSRRYEEQELKEKVSSVDKQREQTEILESSRMRA 934
Query: 424 -------SAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKE 476
+ED + + E +K K Q K +K +DD+ + ++ + D Q
Sbjct: 935 QDIIGHHQSEDRETSDRAHDENKKKAKIQKKPIKKKKEDDVGIERGNIETTSEDGQVFSP 994
Query: 477 EREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTV 536
++ + +K+++EK ++ SK ++ + +Q K + G R P +T
Sbjct: 995 KKGQ-KKKSIEKKRKKSKGDSDISDEEAAQQSKK---------------KRGPRTPPITT 1038
Query: 537 SEASYQSERVEEKGATYPSEIPKEDSTTFAKREDR------VTTEIQLPSQSPVEEQSPA 590
E E K KED T F+ D TE + + + +P+
Sbjct: 1039 KEELV--EMCNGKNGILEDSQKKED-TAFSDWSDEDVPDRTEVTEAEHTATATTPGSTPS 1095
Query: 591 SLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTSVVTPR-PFGSQTRGISSLPRSYTMD 649
LSSL + +T + ++P + T TS T + ++ ++ +
Sbjct: 1096 PLSSLLPPPPPV-ATATATTVPATLAATTAAAATSFSTSAITISTSATPTNTTNNTFANE 1154
Query: 650 DAWK--YNGDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSP 707
D+ + + VE ++ + P + +SSL S + + RL SP++
Sbjct: 1155 DSHRKCHRTRVEKVETPHVTIEDAQHRKPMDQKRSSSLGSNR--SNRSHTSGRLRSPSND 1212
Query: 708 FSSLSQDQAATSKATLSSTS 727
+ S D + K L S S
Sbjct: 1213 SAHRSGDDQSGRKRVLHSGS 1232
Score = 38.5 bits (88), Expect = 0.045
Identities = 38/182 (20%), Positives = 74/182 (40%), Gaps = 27/182 (14%)
Query: 1022 SKSSDREGTRAGEEERRQPQEE-VVHEDQGK-------KPQDQLVIERERK--------- 1064
S SSDR+ +R+ R P+ + VH G + +D+ +RER+
Sbjct: 1262 STSSDRQDSRSHSSRRSSPESDRQVHSRSGSFDSRDRLQERDRYEHDRERERERRDTRQR 1321
Query: 1065 -WEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIPKTEE 1123
W++ ++ + R + E++R E KR+ +++RE I D +T E
Sbjct: 1322 EWDRDADKDWPRNRDRDRLRERERERERDKRR-DLDRERERLISDSVERDRDRDRDRTFE 1380
Query: 1124 AS--------SGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVP 1175
+S L G+ + +T D + +K +K L + + + + E +
Sbjct: 1381 SSQIESVKRCEAKLEGEHERDLESTSRDSLALDKERMDKDLGSVQGFEETNKSERTESLE 1440
Query: 1176 SG 1177
+G
Sbjct: 1441 AG 1442
Score = 33.9 bits (76), Expect = 1.1
Identities = 41/208 (19%), Positives = 81/208 (38%), Gaps = 15/208 (7%)
Query: 367 TTVPPISFTPGPCSEADL----KRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSD 422
T PP+ + P L ++ R S +R K R ER Q + + +
Sbjct: 362 TLTPPLRRSASPYPSHSLSSPQRKQSPPRHRSPMREKGRHDHERTSQSHDRRHERREDTR 421
Query: 423 VSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQD-----DLAKWKDRRKSYTS-DLQKKKE 476
+ ++ R+ R E + S+ D++ +D D +DRR+ S D++ +E
Sbjct: 422 GKRDREKDSREEREYEQDQSSSRDHRDDREPRDGRDRRDARDTRDRRELRDSRDMRDSRE 481
Query: 477 EREEIEKQALEKSKRSSKTFKEM-----LQDRESQNQKSTVPSRRRMYSFDDVLEEGKRP 531
R+ + R S++ ++ + R++ ++ T P R Y + + EE R
Sbjct: 482 MRDYSRDTKESRDPRDSRSTRDAHDYRDREGRDTHRKEDTYPEESRSYGRNHLREESSRT 541
Query: 532 PTMTVSEASYQSERVEEKGATYPSEIPK 559
S +SE ++ +P+
Sbjct: 542 EIRNESRNESRSEIRNDRMGRSRGRVPE 569
Score = 30.8 bits (68), Expect = 9.4
Identities = 50/255 (19%), Positives = 90/255 (35%), Gaps = 42/255 (16%)
Query: 463 RRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFD 522
R K Y+S+ ++ E ++ ++ ++ T + ES + SR R +
Sbjct: 66 RGKGYSSNYRRSPERPTGDLRERMKNKRQDVDTEPQKRNTEESSSPVRKESSRGRHREKE 125
Query: 523 DVLEEGKRPPTMTVSEASYQSER-----------------VEEKGATYPSEIPKEDSTTF 565
D+ +R P +++ R +E K E+ K +
Sbjct: 126 DIKITKERTPESEEENVEWETNRDDSDNGDINYDYVHELSLEMKRQKIQRELMKLEQENM 185
Query: 566 AKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTDTVRLTS 625
KRE+ + + ++ + + SP+ S+S + +S+ S+S + RKT V
Sbjct: 186 EKREE-IIIKKEVSPEVVRSKLSPSPSLRKSSKSPKRKSSPKSSSASKKDRKTSAV---- 240
Query: 626 VVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVSTPAPSPDASQLASSL 685
P Q R K N + RTP S P P P+ L
Sbjct: 241 ---SSPLLDQQRNS-------------KTNQSKKKGPRTP----SPPPPIPEDIALGKKY 280
Query: 686 SSQKEVAATEEDVTR 700
+ +V E+ TR
Sbjct: 281 KEKYKVKDRIEEKTR 295
Score = 30.8 bits (68), Expect = 9.4
Identities = 49/260 (18%), Positives = 102/260 (39%), Gaps = 12/260 (4%)
Query: 435 RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKK--KEEREEIEKQALEKSKRS 492
R +E + + + +E+D++ + + + +DR + +L+++ +E E EK+ + R
Sbjct: 671 RRDERARERDRERERDRERERERERERDREREKERELERERAREREREREKERDRERDRD 730
Query: 493 SKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGAT 552
+E ++RE +K R + E +R A + + E +
Sbjct: 731 RDHDRERERERERDREKEREREREERERERERERERERERERERERARERDKERERQRDW 790
Query: 553 YPSEIPKEDSTTFAK--REDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSAS 610
+ ++D + REDR + +S ++ S S +S + E + S +
Sbjct: 791 EDKDKGRDDRREKREEIREDRNPRDGHDERKSKKRYRNEGSPSPRQSPKRRREHSPDSDA 850
Query: 611 LPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVVS 670
K + RL S V RP ++R +S + WK E+ ++ S
Sbjct: 851 YNSGDDKNEKHRLLSQVV-RP--QESRSLSPSHLTEDRQGRWK-----EEDRKPERKESS 902
Query: 671 TPAPSPDASQLASSLSSQKE 690
+ + SS+ Q+E
Sbjct: 903 RRYEEQELKEKVSSVDKQRE 922
>gi|239745299 PREDICTED: hypothetical protein [Homo sapiens]
Length = 523
Score = 65.9 bits (159), Expect = 3e-10
Identities = 69/272 (25%), Positives = 131/272 (48%), Gaps = 29/272 (10%)
Query: 851 DATSGIYNSEKSSN------------LSVTTDFSESLQSSNIESKEINGIHDESNAFESK 898
D+ +GIY ++S+ L+V D S ++ S E+ IN + S E K
Sbjct: 68 DSATGIYGEGRASSTTLEDLESQYQELAVALDSSSAIISQLTEN--INSLVRTSK--EEK 123
Query: 899 ASESISLKNLKRRSQFFEQGSSDSVVPDLP-----VPTISAPSRWVWDQEEERKRQERWQ 953
E ++ L R + +++ + P+ P V + + + + E RQ + +
Sbjct: 124 KHEIHLVQKLGRSLFKLKNQTAEPLAPEPPAGPSKVEQLQDETNHLRKELESVGRQLQAE 183
Query: 954 KEQDRLLQEKYQREQEKLREEWQRAKQEAER--ENSKYLDEELMVLSSNSMSLTTREPSL 1011
E +++L +R++E+LRE+ +R +++ ER E + L E+ L L +E L
Sbjct: 184 VENNQMLSLLNRRQEERLREQEERLREQEERLREQEERLCEQEERLREQEERLREQEERL 243
Query: 1012 ATWEATWSEGSKS-SDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQ 1070
E E + ++E +EER + QEE +HE + + + + ER R+ E++L
Sbjct: 244 CEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLCEQE---ERLREQEERLC 300
Query: 1071 EEQEQKRLQAE--AEEQKRPAEEQKRQAEIER 1100
E++E+ R Q E E+++R E+++R E E+
Sbjct: 301 EQEERLREQEERLCEQEERLREQEERLCEQEK 332
Score = 57.8 bits (138), Expect = 7e-08
Identities = 77/316 (24%), Positives = 132/316 (41%), Gaps = 29/316 (9%)
Query: 873 ESLQS-SNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPT 931
E LQ +N KE+ + + A E + ++ +SL N ++ + EQ
Sbjct: 160 EQLQDETNHLRKELESVGRQLQA-EVENNQMLSLLNRRQEERLREQEER----------- 207
Query: 932 ISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQR---EQEKLREEWQRAKQEAER--EN 986
+ + +QEE QE +EQ+ L+E+ +R ++E+LRE +R ++ ER E
Sbjct: 208 LREQEERLREQEERLCEQEERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQ 267
Query: 987 SKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVH 1046
+ L E+ L L +E L E E + + R E+E R ++E
Sbjct: 268 EERLREQEERLHEQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERL 327
Query: 1047 EDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRI 1106
+Q K P + ++E K +Q + ++EQ+RL E E EE Q + R+ R+
Sbjct: 328 CEQEKLPGQERLLEEVEKLLEQERRQEEQERL-LERERLLEEVEELLEQERL-RQQDERL 385
Query: 1107 YQYRRPVDSYDIPKTE---EASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMT 1163
+Q + + + E E L R + RS E N NK Q+
Sbjct: 386 WQQETLQELERLRELERMLELGWEALYEQRAEPRSGFE------ELNNENKSTLQLEQQV 439
Query: 1164 SSQRRSKKEQVPSGAE 1179
++S + P G+E
Sbjct: 440 KELKKSGGAEEPRGSE 455
Score = 32.3 bits (72), Expect = 3.2
Identities = 45/244 (18%), Positives = 105/244 (43%), Gaps = 18/244 (7%)
Query: 388 EAIREAS-RLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLR---YEEMQKIK 443
E +RE RLR ++ + E+ + E + E + LR+ +E+ +++
Sbjct: 227 ERLREQEERLREQEERLCEQEERLREHEERLCEQEERLCEQEERLREQEERLHEQEERLC 286
Query: 444 SQ---LKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEI-EKQALEKSKRSSKTFKEM 499
Q L+EQ+++ + + +++ + ++ +E+ E + E++ L +R + +++
Sbjct: 287 EQEERLREQEERLCEQEERLREQEERLCEQEERLREQEERLCEQEKLPGQERLLEEVEKL 346
Query: 500 L-QDRESQNQKSTVPSRRRMYSFDDVLEEGK---------RPPTMTVSEASYQSERVEEK 549
L Q+R + Q+ + R + +++LE+ + + T+ E + ER+ E
Sbjct: 347 LEQERRQEEQERLLERERLLEEVEELLEQERLRQQDERLWQQETLQELERLRELERMLEL 406
Query: 550 GATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA 609
G E E + F + + + +QL Q ++S + S S A
Sbjct: 407 GWEALYEQRAEPRSGFEELNNENKSTLQLEQQVKELKKSGGAEEPRGSESAAAARPVAGA 466
Query: 610 SLPR 613
+P+
Sbjct: 467 PVPQ 470
>gi|115298682 HBxAg transactivated protein 2 [Homo sapiens]
Length = 2817
Score = 65.9 bits (159), Expect = 3e-10
Identities = 64/262 (24%), Positives = 120/262 (45%), Gaps = 30/262 (11%)
Query: 858 NSEKSSNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQ 917
NS K +N + D +N KE + + + ++ + A S++ + F ++
Sbjct: 343 NSPKENN---SEDQGSKASENNENKKETDEVSNTKSSSQIPAQPSVAKVPYGKGPSFNQE 399
Query: 918 GSSDSVVPDLP--------------VPTISAP---SRWVWDQEEERKRQERWQKEQDRLL 960
+ S +P P VP P + V D++E K++ R Q E +
Sbjct: 400 RGTSSHLPPPPKLLAQQHPPPDRQAVPGRPGPFPSKQQVADEDEIWKQRRRQQSEISAAV 459
Query: 961 QE-KYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWS 1019
+ + +RE+E+ R E QR AE+ K LDE+L +L RE
Sbjct: 460 ERARKRREEEERRMEEQRKAACAEK--LKRLDEKLGILEKQPSPEEIREREREKEREREK 517
Query: 1020 EGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQ 1079
E K ++E + E++R + QE+ ++ K+ + Q +E+ERK QE++++ Q
Sbjct: 518 ELEKEQEQEREKEREKDRERQQEK--EKELEKEQEKQREMEKERK-----QEKEKELERQ 570
Query: 1080 AEAEEQKRPAEEQKRQAEIERE 1101
E E++ + +EQ+++ E+E+E
Sbjct: 571 KEKEKELQKMKEQEKECELEKE 592
Score = 42.7 bits (99), Expect = 0.002
Identities = 40/162 (24%), Positives = 71/162 (43%), Gaps = 12/162 (7%)
Query: 435 RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIE---KQALEKSKR 491
R +E ++ K KEQ+Q+ + + K ++R++ +L+K++E++ E+E KQ EK
Sbjct: 509 REKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELE 568
Query: 492 SSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGA 551
K ++ LQ + Q ++ + R E P + E+ + EE
Sbjct: 569 RQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVF 628
Query: 552 TYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLS 593
T ++DS K V E + S S + PA LS
Sbjct: 629 T------RQDSNRSEKEATPVVHETEPESGS---QPRPAVLS 661
Score = 38.9 bits (89), Expect = 0.035
Identities = 52/261 (19%), Positives = 104/261 (39%), Gaps = 31/261 (11%)
Query: 418 KSMSDVSAEDVQNLRQLRYEEMQKIKSQ--------LKEQDQKW-------QDDLAKWKD 462
+ S++SA V+ R+ R EE ++++ Q LK D+K + + ++
Sbjct: 450 RQQSEISAA-VERARKRREEEERRMEEQRKAACAEKLKRLDEKLGILEKQPSPEEIRERE 508
Query: 463 RRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFD 522
R K + + +KE+ +E EK+ + +R + KE+ +++E Q + + + +
Sbjct: 509 REKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKERKQEKEKELE 568
Query: 523 DVLEEGKRPPTMTVSEASYQ--------SERVEEKGATYPSEIPKEDSTTFAKREDRVTT 574
E+ K M E + E++E + + K++S +E+
Sbjct: 569 RQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLEPMVEKQESENSCNKEEEPVF 628
Query: 575 EIQLPSQSP------VEEQSPASLSSLRSRSTQMESTRVSASL-PRSYRKTDTVRLTSVV 627
Q ++S V E P S S R + SL PR R+ + ++
Sbjct: 629 TRQDSNRSEKEATPVVHETEPESGSQPRPAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQ 688
Query: 628 TPRPFGSQTRGISSLPRSYTM 648
+ G + + S P S T+
Sbjct: 689 QQQQQGVLPQTVPSQPSSSTV 709
Score = 38.9 bits (89), Expect = 0.035
Identities = 38/157 (24%), Positives = 79/157 (50%), Gaps = 31/157 (19%)
Query: 941 DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 1000
++++E++++ QKE+++ LQ K++E+ + + E ERE L+E+
Sbjct: 558 ERKQEKEKELERQKEKEKELQ--------KMKEQEKECELEKEREK---LEEK------- 599
Query: 1001 SMSLTTREPSLATW-EATWSEGSKSSDREGTRAGEEERRQPQE--EVVHE---DQGKKPQ 1054
+ REP+L E SE S + + E ++ R +E VVHE + G +P+
Sbjct: 600 ---IEPREPNLEPMVEKQESENSCNKEEEPVFTRQDSNRSEKEATPVVHETEPESGSQPR 656
Query: 1055 DQLVIERERKWEQQL----QEEQEQKRLQAEAEEQKR 1087
++ +++++ L Q +QEQ + Q ++Q++
Sbjct: 657 PAVLSGYFKQFQKSLPPRFQRQQEQMKQQQWQQQQQQ 693
Score = 34.3 bits (77), Expect = 0.85
Identities = 32/130 (24%), Positives = 58/130 (44%), Gaps = 23/130 (17%)
Query: 388 EAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYE-----EMQKI 442
E IRE R + ++R E+ +K + K + ++L E EM+K
Sbjct: 502 EEIREREREKERER---EKELEKEQEQEREKEREKDRERQQEKEKELEKEQEKQREMEKE 558
Query: 443 KSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIE-----KQALEKSKRSSKTFK 497
+ Q KE++ +R+K +LQK KE+ +E E ++ EK + +
Sbjct: 559 RKQEKEKE----------LERQKEKEKELQKMKEQEKECELEKEREKLEEKIEPREPNLE 608
Query: 498 EMLQDRESQN 507
M++ +ES+N
Sbjct: 609 PMVEKQESEN 618
Score = 32.3 bits (72), Expect = 3.2
Identities = 32/150 (21%), Positives = 62/150 (41%), Gaps = 13/150 (8%)
Query: 443 KSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS-----KTFK 497
K Q+ ++D+ W K + R++S S ++ +R E E++ +E+ ++++ K
Sbjct: 435 KQQVADEDEIW-----KQRRRQQSEISAAVERARKRREEEERRMEEQRKAACAEKLKRLD 489
Query: 498 EMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEI 557
E L E Q + R R + E K E ER +EK E
Sbjct: 490 EKLGILEKQPSPEEIREREREKEREREKELEKEQEQEREKEREKDRERQQEKEKELEKEQ 549
Query: 558 PKEDSTTFAKREDRVTTEIQLPSQSPVEEQ 587
K+ +++++ E +L Q E++
Sbjct: 550 EKQREMEKERKQEK---EKELERQKEKEKE 576
Score = 31.6 bits (70), Expect = 5.5
Identities = 22/93 (23%), Positives = 36/93 (38%)
Query: 1274 MRNPSSSVPPPSAGSVKTSTTGVATTQSPTPRSHSPSASQSGSQLRNSVLPVSVTSEALP 1333
+ + S+ P P+A S T + P + P A S S + PVS + A P
Sbjct: 1868 LASTSAPTPAPAASSPAAPVITAPTIPASAPTASVPLAPASASAPAPAPTPVSAPNPAPP 1927
Query: 1334 QELKSGSETTNCTATTAISDSNLDGQPPCDVSL 1366
++ ++T + S QPP + L
Sbjct: 1928 APAQTQAQTHKPVQNPLQTTSQSSKQPPPSIRL 1960
>gi|116089325 splicing factor, arginine/serine-rich 12 isoform a [Homo
sapiens]
Length = 624
Score = 65.5 bits (158), Expect = 3e-10
Identities = 83/377 (22%), Positives = 156/377 (41%), Gaps = 38/377 (10%)
Query: 863 SNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDS 922
SN ++ + Q++ E +E+ E+ +F S A E S K+ +R+ G S S
Sbjct: 256 SNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKG-----GRSRS 310
Query: 923 VVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEA 982
+ SR RKR + K + R R++++ R + K+
Sbjct: 311 HT--------RSKSRSSSKSHSRRKRSQ--SKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 360
Query: 983 ERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE 1042
RE K S TRE + E K DRE R E+ER + +E
Sbjct: 361 SRERRKSRSRS----HSRDKRKDTRE------KIKEKERVKEKDREKEREREKEREKEKE 410
Query: 1043 EVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1102
++D+ K+ + ++E+ E++ ++E E+ R + + +EQ + E +K +++ E
Sbjct: 411 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 470
Query: 1103 SVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNM 1162
+ + R P SY+ + +SS R++S S + + + + + N
Sbjct: 471 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 530
Query: 1163 TSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV-----NKEPVSLP 1217
+R +++ + E ER MRK + + + + S S+ NKEP S
Sbjct: 531 KDKKREKERDHISERRERERS---TSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS-- 585
Query: 1218 GIMRRGESLDNLDSPRS 1234
+ +D+ D+PR+
Sbjct: 586 ---SVSKEVDDKDAPRT 599
Score = 57.4 bits (137), Expect = 9e-08
Identities = 37/191 (19%), Positives = 92/191 (48%), Gaps = 15/191 (7%)
Query: 941 DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 1000
D+E E+ R++ +K+++R +++++++++K +E+ Q ++E E++ SK +DE+
Sbjct: 418 DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK------R 471
Query: 1001 SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIE 1060
+R P ++ A+ S S +R R+ R + + + P + +
Sbjct: 472 KKDKKSRTPP-RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 530
Query: 1061 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP-------- 1112
+++K E++ E++ + +K + ++ + TS++ ++ +
Sbjct: 531 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 590
Query: 1113 VDSYDIPKTEE 1123
VD D P+TEE
Sbjct: 591 VDDKDAPRTEE 601
Score = 51.6 bits (122), Expect = 5e-06
Identities = 57/275 (20%), Positives = 109/275 (39%), Gaps = 17/275 (6%)
Query: 391 REASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQD 450
R S+ HKKR R +K + S+ + E ++ +++ ++ +K + + KE++
Sbjct: 348 RRRSKSPHKKRSK-SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKERE 406
Query: 451 QKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKS 510
+ + + K KDR K D +K KE+ E E++ + R + KE QD+E + +K
Sbjct: 407 K--EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE--KEKEQDKEKEREKD 462
Query: 511 TVPSRRRMYSFDDVLEEGKR----PPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFA 566
R D+ ++ K+ P + S S S R + + S S T
Sbjct: 463 ------RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIK 516
Query: 567 KREDRVTTEIQLPSQSPVEEQSPASLSSL--RSRSTQMESTRVSASLPRSYRKTDTVRLT 624
++ R + + E+ +S R RST M + K T
Sbjct: 517 RKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKE 576
Query: 625 SVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVE 659
P S ++ + T ++ ++NG+ +
Sbjct: 577 KEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQ 611
Score = 45.1 bits (105), Expect = 5e-04
Identities = 51/201 (25%), Positives = 92/201 (45%), Gaps = 19/201 (9%)
Query: 435 RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEI-EKQALEKSKRSS 493
R QK + + K +K + K R +S++ D K+K+ RE+I EK+ +++ R
Sbjct: 340 RSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRD--KRKDTREKIKEKERVKEKDRE- 396
Query: 494 KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATY 553
KE +++E + +K ++ R + E+ K E ++ +R +EK
Sbjct: 397 ---KEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK---- 449
Query: 554 PSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSP--ASLSSLRSRSTQME-STRVSAS 610
KE + +DR + EI + + ++P + +S RSRS+ E R S S
Sbjct: 450 ----EKEQDKEKEREKDR-SKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS 504
Query: 611 LPRSYRKTDTVRLTSVVTPRP 631
RS R + T++ S +P P
Sbjct: 505 SSRSPRTSKTIKRKSSRSPSP 525
>gi|21040255 splicing factor, arginine/serine-rich 12 isoform b [Homo
sapiens]
Length = 508
Score = 65.5 bits (158), Expect = 3e-10
Identities = 83/377 (22%), Positives = 156/377 (41%), Gaps = 38/377 (10%)
Query: 863 SNLSVTTDFSESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDS 922
SN ++ + Q++ E +E+ E+ +F S A E S K+ +R+ G S S
Sbjct: 140 SNNAIVKPPEMTPQAAAKELEEVMKRVREAQSFISAAIEPESGKSNERKG-----GRSRS 194
Query: 923 VVPDLPVPTISAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEA 982
+ SR RKR + K + R R++++ R + K+
Sbjct: 195 HT--------RSKSRSSSKSHSRRKRSQ--SKHRSRSHNRSRSRQKDRRRSKSPHKKRSK 244
Query: 983 ERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQE 1042
RE K S TRE + E K DRE R E+ER + +E
Sbjct: 245 SRERRKSRSRS----HSRDKRKDTRE------KIKEKERVKEKDREKEREREKEREKEKE 294
Query: 1043 EVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1102
++D+ K+ + ++E+ E++ ++E E+ R + + +EQ + E +K +++ E
Sbjct: 295 RGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK 354
Query: 1103 SVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNM 1162
+ + R P SY+ + +SS R++S S + + + + + N
Sbjct: 355 RKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 414
Query: 1163 TSSQRRSKKEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASV-----NKEPVSLP 1217
+R +++ + E ER MRK + + + + S S+ NKEP S
Sbjct: 415 KDKKREKERDHISERRERERS---TSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDS-- 469
Query: 1218 GIMRRGESLDNLDSPRS 1234
+ +D+ D+PR+
Sbjct: 470 ---SVSKEVDDKDAPRT 483
Score = 57.4 bits (137), Expect = 9e-08
Identities = 37/191 (19%), Positives = 92/191 (48%), Gaps = 15/191 (7%)
Query: 941 DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 1000
D+E E+ R++ +K+++R +++++++++K +E+ Q ++E E++ SK +DE+
Sbjct: 302 DKEREKDREKDKEKDREREREKEHEKDRDKEKEKEQDKEKEREKDRSKEIDEK------R 355
Query: 1001 SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIE 1060
+R P ++ A+ S S +R R+ R + + + P + +
Sbjct: 356 KKDKKSRTPP-RSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIKRKSSRSPSPRSRNK 414
Query: 1061 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP-------- 1112
+++K E++ E++ + +K + ++ + TS++ ++ +
Sbjct: 415 KDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKEKEHNKEPDSSVSKE 474
Query: 1113 VDSYDIPKTEE 1123
VD D P+TEE
Sbjct: 475 VDDKDAPRTEE 485
Score = 51.6 bits (122), Expect = 5e-06
Identities = 57/275 (20%), Positives = 109/275 (39%), Gaps = 17/275 (6%)
Query: 391 REASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQD 450
R S+ HKKR R +K + S+ + E ++ +++ ++ +K + + KE++
Sbjct: 232 RRRSKSPHKKRSK-SRERRKSRSRSHSRDKRKDTREKIKEKERVKEKDREKEREREKERE 290
Query: 451 QKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKS 510
+ + + K KDR K D +K KE+ E E++ + R + KE QD+E + +K
Sbjct: 291 K--EKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKE--KEKEQDKEKEREKD 346
Query: 511 TVPSRRRMYSFDDVLEEGKR----PPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFA 566
R D+ ++ K+ P + S S S R + + S S T
Sbjct: 347 ------RSKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRSSSRSPRTSKTIK 400
Query: 567 KREDRVTTEIQLPSQSPVEEQSPASLSSL--RSRSTQMESTRVSASLPRSYRKTDTVRLT 624
++ R + + E+ +S R RST M + K T
Sbjct: 401 RKSSRSPSPRSRNKKDKKREKERDHISERRERERSTSMRKSSNDRDGKEKLEKNSTSLKE 460
Query: 625 SVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVE 659
P S ++ + T ++ ++NG+ +
Sbjct: 461 KEHNKEPDSSVSKEVDDKDAPRTEENKIQHNGNCQ 495
Score = 45.1 bits (105), Expect = 5e-04
Identities = 51/201 (25%), Positives = 92/201 (45%), Gaps = 19/201 (9%)
Query: 435 RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEI-EKQALEKSKRSS 493
R QK + + K +K + K R +S++ D K+K+ RE+I EK+ +++ R
Sbjct: 224 RSRSRQKDRRRSKSPHKKRSKSRERRKSRSRSHSRD--KRKDTREKIKEKERVKEKDRE- 280
Query: 494 KTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATY 553
KE +++E + +K ++ R + E+ K E ++ +R +EK
Sbjct: 281 ---KEREREKEREKEKERGKNKDRDKEREKDREKDKEKDREREREKEHEKDRDKEK---- 333
Query: 554 PSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSP--ASLSSLRSRSTQME-STRVSAS 610
KE + +DR + EI + + ++P + +S RSRS+ E R S S
Sbjct: 334 ----EKEQDKEKEREKDR-SKEIDEKRKKDKKSRTPPRSYNASRRSRSSSRERRRRRSRS 388
Query: 611 LPRSYRKTDTVRLTSVVTPRP 631
RS R + T++ S +P P
Sbjct: 389 SSRSPRTSKTIKRKSSRSPSP 409
>gi|55741709 RNA binding motif protein 25 [Homo sapiens]
Length = 843
Score = 65.1 bits (157), Expect = 5e-10
Identities = 75/365 (20%), Positives = 161/365 (44%), Gaps = 40/365 (10%)
Query: 866 SVTTDFSESL-QSSNIESKEING-----IHDESNAFESKASESISLKNLKRRSQFFEQGS 919
+VT D E+L + + + I G I + S+ + + ES S K++ + +
Sbjct: 187 TVTNDDEEALDEETKRRDQMIKGAIEVLIREYSSELNAPSQESDSHPRKKKKEKKEDIFR 246
Query: 920 SDSVVPDLPVPTISAPSRWVWDQEEERK-----------------RQERWQKEQDRLLQE 962
V P +P P I+ + EE+++ +E+ +KE++R E
Sbjct: 247 RFPVAPLIPYPLITKEDINAIEMEEDKRDLISREISKFRDTHKKLEEEKGKKEKERQEIE 306
Query: 963 KYQREQEKLRE-EWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEG 1021
K +RE+E+ RE E +R ++E ERE + ++E R+ + E
Sbjct: 307 KERRERERERERERERREREREREREREREKEKERERERERD-RDRDRTKERDRDRDRER 365
Query: 1022 SKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAE 1081
+ DRE + ++R + +E+ ++ ++ + + ERER+ E++ + E+E++R +
Sbjct: 366 DRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERERERER 425
Query: 1082 AEEQKRPAEEQKRQA----EIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSR 1137
+++KR EE + A ++ER+ + Y+ + +++I + ++ +R + R
Sbjct: 426 EKDKKRDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEER 485
Query: 1138 STTE----------LDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQ 1187
L+DY +++ Y R + E + E+++ L+
Sbjct: 486 RREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDRKREKEE-LE 544
Query: 1188 EMRKR 1192
E+R+R
Sbjct: 545 EIRQR 549
Score = 49.7 bits (117), Expect = 2e-05
Identities = 49/237 (20%), Positives = 93/237 (39%), Gaps = 32/237 (13%)
Query: 388 EAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLK 447
E RE R R ++R ++ E K + ED E +K++ +L+
Sbjct: 400 EREREREREREREREREREREREREREKDKKRDREEDEEDAY--------ERRKLERKLR 451
Query: 448 EQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKR---------------- 491
E++ +Q+ L W+ R + T + +K+ E EE ++ +++KR
Sbjct: 452 EKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPK 511
Query: 492 --SSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDV----LEEGKRPPTMTVSEASYQSER 545
++ L+DRE + + +R +++ L EG P + ++ER
Sbjct: 512 YYRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAER 571
Query: 546 VEEKGATYPSEIPKEDSTTFAKREDR--VTTEIQLPSQSPVEEQSPASLSSLRSRST 600
+ E +E+ K E R E + P Q P + + +SS S S+
Sbjct: 572 RRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSS 628
Score = 48.1 bits (113), Expect = 6e-05
Identities = 86/405 (21%), Positives = 149/405 (36%), Gaps = 49/405 (12%)
Query: 381 EADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQ 440
E + +R E RE R R ++ ER ++ E + + E ++ + + +
Sbjct: 304 EIEKERRERERERERERERRERERERERER---EREKEKERERERERDRDRDRTKERDRD 360
Query: 441 KIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEML 500
+ + + +++D++ D K + R + + D ++++E E E++ + +R + +E
Sbjct: 361 RDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERERERERERERERERERERERE 420
Query: 501 QDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSE------RVEEKGATYP 554
++RE + K R R +D E K + EA+YQ R +K Y
Sbjct: 421 REREREKDKK----RDREEDEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYE 476
Query: 555 SEIPKEDS-----TTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSA 609
E +E+ AKR + P + A LR R +ME+
Sbjct: 477 KEAEREEERRREMAKEAKRLKEFLEDYDDDRDDPKYYRGSALQKRLRDREKEMEADERDR 536
Query: 610 SLPRSYRKTDTVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWKYNGDVEDIKRTPNNVV 669
+ + RL + P P DA + E +R +
Sbjct: 537 KREKEELEEIRQRLLAEGHPDP------------------DAELQRMEQEAERRRQPQIK 578
Query: 670 STPAPSPDASQLASSLSSQKEVAATEEDVTRLP--SPT-SPFSSLSQDQAATSKATLSST 726
P + + ++E EE+ + P PT P SS +A+ AT +T
Sbjct: 579 QEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGNAT-PNT 637
Query: 727 SGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSLDFG 771
G ES G I P E S Q Q + R I G SL G
Sbjct: 638 PG----DESPCGIIIP-HENSPDQQQPEEHRPKI----GLSLKLG 673
Score = 45.8 bits (107), Expect = 3e-04
Identities = 45/205 (21%), Positives = 91/205 (44%), Gaps = 20/205 (9%)
Query: 941 DQEE--ERKRQERWQKEQDRLLQEKYQ----REQEKLREEWQRAKQEAERENSKYLDEEL 994
D+E+ ER++ ER +E++ QE+ + RE++K RE + A++E ER + +
Sbjct: 436 DEEDAYERRKLERKLREKEAAYQERLKNWEIRERKKTREYEKEAEREEERRREMAKEAKR 495
Query: 995 MVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGK--- 1051
+ +P A + DRE +E R+ ++E + E + +
Sbjct: 496 LKEFLEDYDDDRDDPKYYRGSALQK---RLRDREKEMEADERDRKREKEELEEIRQRLLA 552
Query: 1052 --KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVR---- 1105
P ++R + ++ ++ Q ++ ++E EE+++ +E+KR+ +E E
Sbjct: 553 EGHPDPDAELQRMEQEAERRRQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPC 612
Query: 1106 IYQYRRPVDSYDIPKTEEASSGFLP 1130
+ RP+ S P AS P
Sbjct: 613 LKPTLRPISS--APSVSSASGNATP 635
Score = 37.4 bits (85), Expect = 0.10
Identities = 15/62 (24%), Positives = 35/62 (56%)
Query: 456 DLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSR 515
+++K++D K + KK++ER+EIEK+ E+ + + + ++RE + ++ +
Sbjct: 280 EISKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEK 339
Query: 516 RR 517
R
Sbjct: 340 ER 341
Score = 31.6 bits (70), Expect = 5.5
Identities = 42/189 (22%), Positives = 72/189 (38%), Gaps = 28/189 (14%)
Query: 871 FSESLQSSNI-ESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPV 929
+ E L++ I E K+ E+ E + E K KR +F E D D
Sbjct: 457 YQERLKNWEIRERKKTREYEKEAEREEERRREMA--KEAKRLKEFLEDYDDDR--DDPKY 512
Query: 930 PTISAPSRWVWDQEEERKRQERWQK-----------------------EQDRLLQEKYQR 966
SA + + D+E+E + ER +K E R+ QE +R
Sbjct: 513 YRGSALQKRLRDREKEMEADERDRKREKEELEEIRQRLLAEGHPDPDAELQRMEQEAERR 572
Query: 967 EQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSD 1026
Q ++++E + ++E E++ + EE M +P+L + S S S +
Sbjct: 573 RQPQIKQEPESEEEEEEKQEKEEKREEPMEEEEEPEQKPCLKPTLRPISSAPSVSSASGN 632
Query: 1027 REGTRAGEE 1035
G+E
Sbjct: 633 ATPNTPGDE 641
Score = 30.8 bits (68), Expect = 9.4
Identities = 30/176 (17%), Positives = 66/176 (37%), Gaps = 3/176 (1%)
Query: 444 SQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDR 503
S+ ++ +K +++ K + R+ + ++++ ERE ++ + +R + +E ++R
Sbjct: 282 SKFRDTHKKLEEEKGKKEKERQEIEKERRERERERERERERREREREREREREREKEKER 341
Query: 504 ESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDST 563
E + ++ R + D E + S+ + R EK E +E
Sbjct: 342 ERERERDRDRDRTKERDRDRDRERDRDRDRERSSDRNKDRSRSREKSRDRERERERERE- 400
Query: 564 TFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSYRKTD 619
+RE E + + E + R R E L R R+ +
Sbjct: 401 --REREREREREREREREREREREREREKDKKRDREEDEEDAYERRKLERKLREKE 454
>gi|239752551 PREDICTED: hypothetical protein [Homo sapiens]
Length = 238
Score = 64.3 bits (155), Expect = 8e-10
Identities = 48/181 (26%), Positives = 94/181 (51%), Gaps = 21/181 (11%)
Query: 942 QEEERKRQ-ERWQKEQDRLL---QEKYQREQEKLREE----WQRAKQEAERENSKYLDEE 993
+EEER R+ E+ +E++ ++ +EK Q ++EK+RE+ W++ ++ E+E + EE
Sbjct: 2 REEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEE 61
Query: 994 LMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEE---------ERRQPQEEV 1044
M M R P E W + + ++E ++ E+++ QEE
Sbjct: 62 KMWEQEEKMWEQQRLPEQK--EKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119
Query: 1045 VHEDQGK-KPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETS 1103
+ E + K + Q++++ E+E K ++Q ++ EQ+ E EE+ R +E+K Q + E+
Sbjct: 120 MQEQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMR-EQEEKMQGQEEKMRD 178
Query: 1104 V 1104
V
Sbjct: 179 V 179
Score = 63.2 bits (152), Expect = 2e-09
Identities = 49/161 (30%), Positives = 82/161 (50%), Gaps = 24/161 (14%)
Query: 939 VWDQEEERKRQER--WQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMV 996
+W+QEE+ + QE W++E+ QE+ EQ++L E+ ++ ++ ER K EE M
Sbjct: 42 MWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREK---EERM- 97
Query: 997 LSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQ 1056
RE + W+ K +E +EE+ Q QEE++ E Q +K Q+Q
Sbjct: 98 ----------REQKM--WQQVEKMREKKKTQEEKMQEQEEKMQEQEEMMWE-QEEKMQEQ 144
Query: 1057 LVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAE 1097
E+ WEQ+ ++ +EQ+ E EE+ + EE+ R E
Sbjct: 145 ----EEKMWEQE-EKMREQEEKMREQEEKMQGQEEKMRDVE 180
Score = 45.4 bits (106), Expect = 4e-04
Identities = 38/170 (22%), Positives = 83/170 (48%), Gaps = 15/170 (8%)
Query: 390 IREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQ 449
+RE R+R +++ M E E + + E + + + + E+MQ+ + ++ EQ
Sbjct: 1 MREEERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWE-QEEKMQEQEEKMWEQ 59
Query: 450 DQK-WQDDLAKWKDRR------KSYTSDLQ-KKKEEREEIEK--QALEKSKRSSKTFKEM 499
++K W+ + W+ +R K + D + ++KEER +K Q +EK + KT +E
Sbjct: 60 EEKMWEQEEKMWEQQRLPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEK 119
Query: 500 LQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEK 549
+Q++E + Q+ M+ ++ ++E + + Q E++ E+
Sbjct: 120 MQEQEEKMQE----QEEMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQ 165
Score = 34.3 bits (77), Expect = 0.85
Identities = 22/101 (21%), Positives = 51/101 (50%), Gaps = 11/101 (10%)
Query: 385 KRWEAIREASRLRHKK-RLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIK 443
K WE + RLR K+ R+ ++++Q++ K + ++ + E+MQ+ +
Sbjct: 82 KMWE---QDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQEQE-------EKMQEQE 131
Query: 444 SQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQ 484
+ EQ++K Q+ K ++ + +K +E+ E+++ Q
Sbjct: 132 EMMWEQEEKMQEQEEKMWEQEEKMREQEEKMREQEEKMQGQ 172
Score = 32.0 bits (71), Expect = 4.2
Identities = 31/159 (19%), Positives = 67/159 (42%), Gaps = 9/159 (5%)
Query: 1060 ERERKWEQQLQEEQEQKRLQAE---AEEQKRPAEEQK--RQAEIERETSVRIYQYRRPVD 1114
ER R+ E++++EE+E R Q E +E+K +E+K Q E +E ++++ +
Sbjct: 5 ERMREREKKMREEEEMMREQEEKMQEQEEKMREQEEKMWEQEEKMQEQEEKMWEQEEKMW 64
Query: 1115 SYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQR-RSKKEQ 1173
+ E+ LP + K E + K Q+ M ++ + +K Q
Sbjct: 65 EQEEKMWEQQR---LPEQKEKMWEQDERLREKEERMREQKMWQQVEKMREKKKTQEEKMQ 121
Query: 1174 VPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKE 1212
E+++++ E ++ + W ++ +E
Sbjct: 122 EQEEKMQEQEEMMWEQEEKMQEQEEKMWEQEEKMREQEE 160
>gi|239747134 PREDICTED: hypothetical protein XP_002343921 [Homo
sapiens]
Length = 600
Score = 63.9 bits (154), Expect = 1e-09
Identities = 57/263 (21%), Positives = 112/263 (42%), Gaps = 25/263 (9%)
Query: 942 QEEERKRQERW-QKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 1000
+E ER+R++R ++E DR + + ++++ + R+ + +++ E+E + D E
Sbjct: 60 KERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERERQTDRE------- 112
Query: 1001 SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIE 1060
R+ E + ++REG R + + +E D K+ + Q E
Sbjct: 113 ------RDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRE 166
Query: 1061 RERKWEQQLQEEQEQKRLQAEAEEQKRPAE----------EQKRQAEIERETSVRIYQYR 1110
R+R+ E+ Q+E+E+++ + E E++R E E+ R+ E ERET + R
Sbjct: 167 RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR 226
Query: 1111 RPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQR-RS 1169
+ D + E S TE D + ++ D+ Q R
Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQKERERQTDRK 286
Query: 1170 KKEQVPSGAELERQQILQEMRKR 1192
++ + E ER++ Q R+R
Sbjct: 287 RQRRTERDRETERKRERQRERER 309
Score = 63.2 bits (152), Expect = 2e-09
Identities = 66/273 (24%), Positives = 117/273 (42%), Gaps = 26/273 (9%)
Query: 941 DQEEERKRQERWQKEQDRLLQEKYQREQEKLRE-EWQRAKQEAE-RENSKYLDEELMVLS 998
D + ER+RQ +KE++R + QR+ E+ R+ E +R K E RE + ++E
Sbjct: 144 DGQRERERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTED 203
Query: 999 SNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEER---RQPQEEVVHE---DQGKK 1052
+S RE T T +E + +DRE R + ER +Q + E E ++ K+
Sbjct: 204 RHSERGRERERERET--ETETERKRQTDRERDRQRKTEREREKQAERERASERETERDKE 261
Query: 1053 PQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP 1112
+ + +R+R Q+ +E Q ++ Q E + +++RQ E ERE + R
Sbjct: 262 RERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERERERNRKRERER 321
Query: 1113 VDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKE 1172
+ + E K + TE+D + G +R++++E
Sbjct: 322 ERERERERQRETERDREKERERKRKRQTEMDRERNRQTGR-----------EGRRQAERE 370
Query: 1173 QVPSGAELERQQILQEMRKRTPLHNDNSWIRQR 1205
+ E ER++ Q R+R D RQ+
Sbjct: 371 R-----ERERERDRQSAREREERERDRDRDRQK 398
Score = 56.6 bits (135), Expect = 2e-07
Identities = 49/196 (25%), Positives = 87/196 (44%), Gaps = 23/196 (11%)
Query: 941 DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 1000
++E RKR+ ++E++R Q + +R++EK RE ++ + E +RE ++ E +
Sbjct: 310 ERERNRKRERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAER 369
Query: 1001 SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQDQLVIE 1060
RE A E + DR+ R E ER+ + +
Sbjct: 370 ERE---RERERDRQSARERE-ERERDRDRDRQKERERQTEK------------------D 407
Query: 1061 RERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQK-RQAEIERETSVRIYQYRRPVDSYDIP 1119
R+ + E + Q E+E+ R E+ R E+QK R+ + ER+T + + R+ Y P
Sbjct: 408 RDGQRETEKQREREKDRESERGRERGREREKQKGRERDRERQTDRQAGRQRKRSTLYVNP 467
Query: 1120 KTEEASSGFLPGDRNK 1135
A SG + D N+
Sbjct: 468 PPRTARSGVVQSDPNR 483
Score = 56.2 bits (134), Expect = 2e-07
Identities = 51/218 (23%), Positives = 91/218 (41%), Gaps = 46/218 (21%)
Query: 941 DQEEERKR-----QERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELM 995
D+E ER+R ++R QKE++R K QR E+ RE ++ +++ ERE +
Sbjct: 259 DKERERERDRDRDRDRRQKERERQTDRKRQRRTERDRETERKRERQRERERER------- 311
Query: 996 VLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKKPQD 1055
E ++ +RE R E ER++ E +++ +K +
Sbjct: 312 ------------------------ERNRKRERERERERERERQRETERDREKERERKRKR 347
Query: 1056 QLVIERER----------KWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVR 1105
Q ++RER + E++ + E+E+ R A E++ ++ RQ E ER+T
Sbjct: 348 QTEMDRERNRQTGREGRRQAERERERERERDRQSAREREERERDRDRDRQKERERQTEKD 407
Query: 1106 IYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELD 1143
R + K E+ G G + + E D
Sbjct: 408 RDGQRETEKQREREKDRESERGRERGREREKQKGRERD 445
Score = 48.1 bits (113), Expect = 6e-05
Identities = 37/164 (22%), Positives = 74/164 (45%), Gaps = 2/164 (1%)
Query: 941 DQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSN 1000
++E ER+RQ ++++++ + K +R+ E RE ++ +E R+ + + E +
Sbjct: 322 ERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERERDRQS 381
Query: 1001 SMSLTTREPSLATWEATWSEGSKSSDREGTRAGEE--ERRQPQEEVVHEDQGKKPQDQLV 1058
+ RE E DR+G R E+ ER + +E ++G++ + Q
Sbjct: 382 AREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGREREKQKG 441
Query: 1059 IERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERET 1102
ER+R+ + Q +++KR R A Q++ R T
Sbjct: 442 RERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPT 485
Score = 45.8 bits (107), Expect = 3e-04
Identities = 55/230 (23%), Positives = 89/230 (38%), Gaps = 22/230 (9%)
Query: 1026 DREGTRAGEEERRQPQEEVVHEDQGKKP---QDQLVIERERKWEQQLQEEQEQKRLQAEA 1082
DRE R E ERR+ + + E K+ + +R+R E+Q E+E++R Q +
Sbjct: 53 DRERNRQKERERRREKRQTERETDRKRERRREKDRHRKRDRHRERQRDREKERER-QTDR 111
Query: 1083 EEQKRPAEEQKRQAEIERETSVRIYQYR-RPVDSY-------DIPKTEEASSGFLPGDRN 1134
E ++ +E+ RQ E ERET + R R D D K E + DR
Sbjct: 112 ERDRQREKERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQT-----DRE 166
Query: 1135 KSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQ---EMRK 1191
+ R T + N + + + +++ G E ER++ + E ++
Sbjct: 167 RQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSERGRERERERETETETERKR 226
Query: 1192 RTPLHND--NSWIRQRSASVNKEPVSLPGIMRRGESLDNLDSPRSNSWRQ 1239
+T D R+R +E S R E D R RQ
Sbjct: 227 QTDRERDRQRKTEREREKQAERERASERETERDKERERERDRDRDRDRRQ 276
Score = 37.4 bits (85), Expect = 0.10
Identities = 47/235 (20%), Positives = 95/235 (40%), Gaps = 17/235 (7%)
Query: 435 RYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSK 494
R +E ++ + + +++D++ Q + + DR++ ++ ++ E + E +++ + +R+ K
Sbjct: 258 RDKERERERDRDRDRDRR-QKERERQTDRKRQRRTERDRETERKRERQRERERERERNRK 316
Query: 495 TFKEMLQDRESQNQKSTVPSR------RRMYSFDDVLEEGKRPPTMTVSEASYQSERVEE 548
+E ++RE + Q+ T R +R + E ++ +A + ER E
Sbjct: 317 RERERERERERERQRETERDREKERERKRKRQTEMDRERNRQTGREGRRQAERERERERE 376
Query: 549 KG--ATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQ--SPASLSSLRSRSTQMES 604
+ + E + D ++E TE Q E+Q S R R E
Sbjct: 377 RDRQSAREREERERDRDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRERGRER 436
Query: 605 TRVSASLPRSYRKTD------TVRLTSVVTPRPFGSQTRGISSLPRSYTMDDAWK 653
+ R+TD R T V P P +++ + S P T WK
Sbjct: 437 EKQKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWK 491
Score = 37.4 bits (85), Expect = 0.10
Identities = 46/186 (24%), Positives = 77/186 (41%), Gaps = 17/186 (9%)
Query: 388 EAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLK 447
E RE R R K+R ER +K E + E + + R E ++ + +
Sbjct: 328 ERQRETERDREKER---ERK-RKRQTEMDRERNRQTGREGRRQAERERERERERDRQSAR 383
Query: 448 EQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQN 507
E++++ +D + +DR+K +K ++ + E EKQ + R S+ +E + RE +
Sbjct: 384 EREERERD---RDRDRQKERERQTEKDRDGQRETEKQREREKDRESERGRE--RGREREK 438
Query: 508 QKSTVPSRRRMYSFDDVLEEGK-----RPPTMTVSEASYQSE-RVEEKGATYPS--EIPK 559
QK R R + + PP T QS+ +G + S E PK
Sbjct: 439 QKGRERDRERQTDRQAGRQRKRSTLYVNPPPRTARSGVVQSDPNRPTRGIRWKSSPEDPK 498
Query: 560 EDSTTF 565
ST F
Sbjct: 499 AASTRF 504
Score = 35.4 bits (80), Expect = 0.38
Identities = 37/186 (19%), Positives = 75/186 (40%), Gaps = 10/186 (5%)
Query: 422 DVSAEDVQNLRQLRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEI 481
D +D + RQ E ++ + +E D+K + + KDR + +++++ +E
Sbjct: 48 DADGDDRERNRQKERERRREKRQTERETDRK--RERRREKDRHRKRDRHRERQRDREKER 105
Query: 482 EKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASY 541
E+Q + R + + ++RE + ++ R R D E ++ E
Sbjct: 106 ERQTDRERDRQREKERNRQKERERETEREGERGRDR--QTDGQRERERQRDAEKERERQT 163
Query: 542 QSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQ-SPASLSSLRSRST 600
ER + E +E + R++R E Q ++ E++ S R R T
Sbjct: 164 DRERQRQTERNRQKEREREKN-----RQERRERERQREKENKTEDRHSERGRERERERET 218
Query: 601 QMESTR 606
+ E+ R
Sbjct: 219 ETETER 224
Score = 34.7 bits (78), Expect = 0.65
Identities = 41/226 (18%), Positives = 91/226 (40%), Gaps = 35/226 (15%)
Query: 381 EADLKRWEAIREASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQ 440
E D KR R + RH+KR + + D E + + R + +
Sbjct: 74 ETDRKRE---RRREKDRHRKR------------DRHRERQRDREKERERQTDRERDRQRE 118
Query: 441 KIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEML 500
K +++ KE++++ + + + +DR+ + +++++ +E E+Q + +R ++ ++
Sbjct: 119 KERNRQKERERETEREGERGRDRQTDGQRERERQRDAEKERERQTDRERQRQTERNRQKE 178
Query: 501 QDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKE 560
++RE Q+ R+R + + +R E+G E E
Sbjct: 179 REREKNRQERRERERQR-------------------EKENKTEDRHSERGRERERERETE 219
Query: 561 DSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTR 606
T ++ DR + Q ++ E+Q+ +S R E R
Sbjct: 220 TETERKRQTDR-ERDRQRKTEREREKQAERERASERETERDKERER 264
Score = 33.9 bits (76), Expect = 1.1
Identities = 41/181 (22%), Positives = 77/181 (42%), Gaps = 12/181 (6%)
Query: 1018 WSEGSKSSDREGTRAGEEE--RRQPQEEVVHEDQGKKPQDQLVIERERKWE-QQLQEEQE 1074
W E + D R G +E RR+ + + G + ERER+ E +Q + E +
Sbjct: 17 WVEVTIPLDFSRRRPGSQESPRRRGLGQAHKDADGDDRERNRQKERERRREKRQTERETD 76
Query: 1075 QKRLQAEAEEQKRPAE---EQKRQAEIERETSVRIYQYRRPVDSYDIPKTEEASSGFLPG 1131
+KR + +++ R + E++R E ERE + R+ + K E + G
Sbjct: 77 RKRERRREKDRHRKRDRHRERQRDREKERERQTDRERDRQREKERNRQKERERETE-REG 135
Query: 1132 DRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGAELERQQILQEMRK 1191
+R + R T + ++ + Q + + R ++ + E ER++ QE R+
Sbjct: 136 ERGRDRQTDGQRERERQRDAEKERERQ-----TDRERQRQTERNRQKEREREKNRQERRE 190
Query: 1192 R 1192
R
Sbjct: 191 R 191
Score = 32.3 bits (72), Expect = 3.2
Identities = 41/217 (18%), Positives = 85/217 (39%), Gaps = 11/217 (5%)
Query: 391 REASRLRHKKR-LMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLKEQ 449
RE R K+R +R Q+ N K + R+ + E+ K + + E+
Sbjct: 149 RERQRDAEKERERQTDRERQRQTERNRQKEREREKNRQERRERERQREKENKTEDRHSER 208
Query: 450 DQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQK 509
++ + + + + +D ++ ++ + E E++ + +R+S+ +E +D+E + ++
Sbjct: 209 GRERERERETETETERKRQTDRERDRQRKTEREREKQAERERASE--RETERDKERERER 266
Query: 510 STVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKRE 569
R R + + KR +E ++ER E+ E + KRE
Sbjct: 267 DRDRDRDRRQKERERQTDRKR---QRRTERDRETERKRERQRERERERERN-----RKRE 318
Query: 570 DRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMESTR 606
E + Q E R R T+M+ R
Sbjct: 319 RERERERERERQRETERDREKERERKRKRQTEMDRER 355
>gi|4503509 eukaryotic translation initiation factor 3, subunit 10
theta, 150/170kDa [Homo sapiens]
Length = 1382
Score = 62.8 bits (151), Expect = 2e-09
Identities = 87/415 (20%), Positives = 162/415 (39%), Gaps = 62/415 (14%)
Query: 873 ESLQSSNIESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPDLPVPTI 932
E L I +K++ + E + + LKN +++ +FE+ +P +
Sbjct: 662 EELDPDFIMAKQVEQLEKEKKELQER------LKNQEKKIDYFERAKRLEEIPLIKSAY- 714
Query: 933 SAPSRWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDE 992
+E+ K + W+++++ + Q E+EK E R + E D
Sbjct: 715 ---------EEQRIKDMDLWEQQEEERITTM-QLEREKALEHKNRMSRMLE-------DR 757
Query: 993 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1052
+L V+ + + E L +E +E + E R +EERR E++ ++
Sbjct: 758 DLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRR 817
Query: 1053 PQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRP 1112
++Q++ ERE + + + +E+ R E ++ E +KRQ E+E E R + R
Sbjct: 818 AEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRREEERR 877
Query: 1113 VDSYDIPKTEEASSGFLPGDRNKS---RSTTELDDYSTNKNGNNKYLDQIGNMTSSQRRS 1169
+ + + + GDR+ R E D S + G + + G R
Sbjct: 878 LGDSSLSRKDSRW-----GDRDSEGTWRKGPEAD--SEWRRGPPEKEWRRGEGRDEDRSH 930
Query: 1170 KKEQVPSGAELERQQILQEMRKRTP-LHNDNSWIRQRSASVNKEPVSLPGIMRRGESLDN 1228
++++ ER + L + R P L D+ + +R ++ P RRG D
Sbjct: 931 RRDE-------ERPRRLGDDEDREPSLRPDDDRVPRRGMDDDRGP-------RRGPEEDR 976
Query: 1229 LDSPRSNSWRQPPWLNQPTGFYASSSVQDFSRPPPQLVSTSNRAYMRNPSSSVPP 1283
S R +P W N D R PP+ ++ +R R+ PP
Sbjct: 977 F-SRRGADDDRPSWRN-----------TDDDR-PPRRIADEDRGNWRHADDDRPP 1018
Score = 49.3 bits (116), Expect = 3e-05
Identities = 63/302 (20%), Positives = 122/302 (40%), Gaps = 94/302 (31%)
Query: 943 EEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAK----------------------- 979
EEER RQE ++E++R+LQE Q +++ +RE ++ K
Sbjct: 608 EEERLRQEAKEREKERILQEHEQIKKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPD 667
Query: 980 -----------------QEAERENSKYLD--------EELMVLSSNSMSLTTREPSLATW 1014
QE + K +D EE+ ++ S ++ L W
Sbjct: 668 FIMAKQVEQLEKEKKELQERLKNQEKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDL--W 725
Query: 1015 EATWSEGSKSSDREGTRAGEEERRQPQ---------------EEVVHEDQGKKPQDQLVI 1059
E E + E +A E + R + + V+E++ K+ +++L
Sbjct: 726 EQQEEERITTMQLEREKALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAE 785
Query: 1060 ERERKWEQQLQEEQEQKRL----QAEAEEQKR-------PAEEQKRQAEIERETSVRIYQ 1108
ER + E++ ++ +E++R+ + E EEQ+R EE++R +RE +R YQ
Sbjct: 786 ERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQ 845
Query: 1109 YRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQIGNMTSSQRR 1168
R + K EE +R K + E+++ + + +G+ + S++
Sbjct: 846 ER-------VKKLEEV-------ERKKRQRELEIEERERRREEERR----LGDSSLSRKD 887
Query: 1169 SK 1170
S+
Sbjct: 888 SR 889
Score = 42.7 bits (99), Expect = 0.002
Identities = 43/200 (21%), Positives = 85/200 (42%), Gaps = 17/200 (8%)
Query: 935 PSRWVWDQEEERKRQERW--QKEQDRLLQEKYQREQEKLREEWQRAKQ----EAERENSK 988
P W +E+E+ R+E W +E + ++ RE+E+ R+ R + E ER+ +
Sbjct: 1175 PGGW---REKEKAREESWGPPRESRPSEEREWDREKERDRDNQDREENDKDPERERDRER 1231
Query: 989 YLDEELMVLSSNSMSLTTREPSLATWEATWSEGSK--SSDREGTRAGEEERRQPQEEVVH 1046
+D E R P A ++W + S+ DR+ R ++RR +E
Sbjct: 1232 DVDREDRFRRPRDEGGWRRGP--AEESSSWRDSSRRDDRDRDDRRRERDDRRDLRERRDL 1289
Query: 1047 EDQGKKPQDQLVIERERKWEQQLQEEQEQKRLQAEAEEQKRP----AEEQKRQAEIERET 1102
D + L ERE + ++++ R++ ++ P + +++R + ERE
Sbjct: 1290 RDDRDRRGPPLRSEREEVSSWRRADDRKDDRVEERDPPRRVPPPALSRDRERDRDREREG 1349
Query: 1103 SVRIYQYRRPVDSYDIPKTE 1122
+R D + +T+
Sbjct: 1350 EKEKASWRAEKDRESLRRTK 1369
Score = 35.4 bits (80), Expect = 0.38
Identities = 44/202 (21%), Positives = 91/202 (45%), Gaps = 25/202 (12%)
Query: 399 KKRLMVERLFQKIYGENGSKSMSDVSAEDVQNL-----RQLRYEEMQKIKSQLKEQDQKW 453
KK+ + ERL Q E G+K+ D+ ED++ L + E+++K K +L+E+ +
Sbjct: 632 KKKTVRERLEQIKKTELGAKAFKDIDIEDLEELDPDFIMAKQVEQLEKEKKELQERLKNQ 691
Query: 454 QDDLAKWKDRRKSYTSDLQKKKEEREEIEKQAL-EKSKRSSKTFKEMLQDR--ESQNQKS 510
+ + ++ ++ L K E + I+ L E+ + T ++ +++ E +N+ S
Sbjct: 692 EKKIDYFERAKRLEEIPLIKSAYEEQRIKDMDLWEQQEEERITTMQLEREKALEHKNRMS 751
Query: 511 TVPSRRRMY------SFDDVLEEGKRPPTMTVSEASY------QSERVEEKGATYPSEIP 558
+ R ++ + V EE + ++E + + +R EE+ TY E
Sbjct: 752 RMLEDRDLFVMRLKAARQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKE 811
Query: 559 KE-----DSTTFAKREDRVTTE 575
+E + +RE+R E
Sbjct: 812 EEEQRRAEEQMLKEREERERAE 833
Score = 31.2 bits (69), Expect = 7.2
Identities = 31/134 (23%), Positives = 65/134 (48%), Gaps = 10/134 (7%)
Query: 385 KRWEAIREASRLRHKKRLMVERLF---QKIYGENGSKSMSDVSAEDVQNL----RQLRYE 437
K E SR+ + L V RL Q +Y E K + AE+ N ++ R E
Sbjct: 742 KALEHKNRMSRMLEDRDLFVMRLKAARQSVYEEK-LKQFEERLAEERHNRLEERKRQRKE 800
Query: 438 EMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQA--LEKSKRSSKT 495
E + + KE++++ + + K+R + ++ K++EE E +++ LE+ +R +
Sbjct: 801 ERRITYYREKEEEEQRRAEEQMLKEREERERAERAKREEELREYQERVKKLEEVERKKRQ 860
Query: 496 FKEMLQDRESQNQK 509
+ +++RE + ++
Sbjct: 861 RELEIEERERRREE 874
Score = 30.8 bits (68), Expect = 9.4
Identities = 28/135 (20%), Positives = 57/135 (42%), Gaps = 18/135 (13%)
Query: 432 RQLRYEE-MQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSK 490
RQ YEE +++ + +L E+ ++ + + + T +K++EE+ E+Q
Sbjct: 768 RQSVYEEKLKQFEERLAEERHNRLEERKRQRKEERRITYYREKEEEEQRRAEEQ------ 821
Query: 491 RSSKTFKEMLQDRESQNQKSTVPSRRRMYSFDD---VLEEGKRPPTMTVSEASYQSERVE 547
ML++RE + + + + + LEE +R E + R E
Sbjct: 822 --------MLKEREERERAERAKREEELREYQERVKKLEEVERKKRQRELEIEERERRRE 873
Query: 548 EKGATYPSEIPKEDS 562
E+ S + ++DS
Sbjct: 874 EERRLGDSSLSRKDS 888
>gi|102467242 inner centromere protein antigens 135/155kDa isoform 2
[Homo sapiens]
Length = 914
Score = 62.4 bits (150), Expect = 3e-09
Identities = 147/730 (20%), Positives = 274/730 (37%), Gaps = 124/730 (16%)
Query: 461 KDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQKSTVPSRRRMYS 520
K RR SY D E R+ I ++ + RSS+ L+ ++S + +TV
Sbjct: 67 KKRRISYVQD-----ENRDPIRRRLSRRKSRSSQLSSRRLRSKDSVEKLATV-------- 113
Query: 521 FDDVLEEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLP- 579
V E G +T + A+ + + PS E T K+ + T+ QL
Sbjct: 114 ---VGENGSVLRRVTRAAAAAAAATM---ALAAPSSPTPESPTMLTKKPEDNHTQCQLVP 167
Query: 580 ------SQSPVEEQSPASLSSLRSRSTQMESTRVSASLPRSY----------------RK 617
S+ EQ L S + T SA+ P S R
Sbjct: 168 VVEIGISERQNAEQHVTQLMSTEPLPRTLSPTPASATAPTSQGIPTSDEESTPKKSKARI 227
Query: 618 TDTVRLTSVV-TPRPFGSQTRG------------ISSLPRSYTM--DDAWKYN------- 655
+++ ++S++ TP+ Q G +S PR D W+
Sbjct: 228 LESITVSSLMATPQDPKGQGVGTGRSASKLRIAQVSPGPRDSPAFPDSPWRERVLAPILP 287
Query: 656 -------GDVEDIKRTPNNVVSTPAPSPDASQLASSLSSQKEVAATEEDVTRLPSPTSPF 708
G D + ++ ++ +PSP L+ + + A +E V R S
Sbjct: 288 DNFSTPTGSRTDSQSVRHSPIAPSSPSPQV------LAQKYSLVAKQESVVRRASRRLA- 340
Query: 709 SSLSQDQAATSKATLSSTSGLDLMSESGEGEISPQREVSRSQDQFSDMRISINQTPGKSL 768
+++ AA+ + S L E + S Q+E + + + + G +
Sbjct: 341 KKTAEEPAASGRIICHSYLERLLNVEVPQKVGSEQKEPPEEAEPVAAAEPEVPENNGNNS 400
Query: 769 --DFGFTIKWDIPGIFVASVEAGSPAEFSQLQVDDEIIAINNTKFSYNDSKEWEEAMAKA 826
I P A+ +P+ Q D+ S + +++A+++
Sbjct: 401 WPHNDTEIANSTPNPKPAASSPETPSAGQQEAKTDQADGPREPPQSARRKRSYKQAVSEL 460
Query: 827 QETGHLVMDVRRYGKAGSPETKWIDAT------SGIYNSEKSSNLSVTTDFSESLQSSNI 880
E HL + + ++ +P + + + ++ +++ L T S+ S I
Sbjct: 461 DEEQHLEDEELQPPRSKTPSSPCPASKVVRPLRTFLHTVQRNQMLMTPTSAPRSVMKSFI 520
Query: 881 ESKEINGIHDESNAFESKASESISLKNLKRRSQFFEQGSSDSVVPD----LPVPTISAPS 936
+ + + K E L+NL+R+ + EQ V D L +
Sbjct: 521 K-------RNTPLRMDPKEKERQRLENLRRKEEA-EQLRRQKVEEDKRRRLEEVKLKREE 572
Query: 937 RW---------VWDQEEERKRQ---------ERWQK-EQDRLLQEKYQREQ--EKLREEW 975
R V +EE+K+Q E+ +K +++RL +EK +++ +K+ E
Sbjct: 573 RLRKVLQARERVEQMKEEKKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVE 632
Query: 976 QRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEE 1035
R KQE E ++L +E + +E + RE R +E
Sbjct: 633 ARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQE 692
Query: 1036 ERRQPQEEVVHEDQGKKPQDQLVIERERKWEQQ-LQEEQE----QKRLQAEAEEQKRPAE 1090
R Q + E +Q ++ Q++ + E+ER+ EQ+ LQ E+E +K L+ + E+ +R E
Sbjct: 693 RREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRLQKEQLQRELE 752
Query: 1091 EQKRQAEIER 1100
E+K++ E +R
Sbjct: 753 EKKKKEEQQR 762
Score = 60.5 bits (145), Expect = 1e-08
Identities = 54/192 (28%), Positives = 94/192 (48%), Gaps = 23/192 (11%)
Query: 942 QEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLDEELMVLSSNS 1001
+E E+ R+++ ++++ R L+E + +E+LR+ Q ++ + + K E +
Sbjct: 545 EEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQIDE 604
Query: 1002 MSLTTREPSLATWEATWSEGSKSSDR-EGTRAGEEERR------QPQEEVVHED--QGKK 1052
+ +E LA +A +K + E R EEE R Q +EE H++ Q KK
Sbjct: 605 KTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKK 664
Query: 1053 PQDQ-----------LVIERE---RKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEI 1098
++Q L +RE R+ E++ QE +EQ+R + E EQ+R EQ+R+ E
Sbjct: 665 EEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERREQERQLAEQERRREQ 724
Query: 1099 ERETSVRIYQYR 1110
ER + R Q R
Sbjct: 725 ERLQAERELQER 736
Score = 58.2 bits (139), Expect = 6e-08
Identities = 45/148 (30%), Positives = 75/148 (50%), Gaps = 17/148 (11%)
Query: 937 RWVWDQEEERKRQERWQKEQDRLLQEKYQREQEKLREEWQRAK----QEAERENSKYLDE 992
RW+ +EEER+ QE LLQ+K + EQE+LR+ + + +E ER + ++
Sbjct: 645 RWLQQEEEERRHQE--------LLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQ 696
Query: 993 ELMVLSSNSMSLTTREPSLATWEATWSEGSKSSDREGTRAGEEERRQPQEEVVHEDQGKK 1052
E +E LA E + ++RE + E+ R +E++ E + KK
Sbjct: 697 ERREQERREQERREQERQLAEQERRREQERLQAERE-LQEREKALRLQKEQLQRELEEKK 755
Query: 1053 PQDQLVIERERKWEQQLQEEQEQKRLQA 1080
++ E++R E+QLQEEQE+K +A
Sbjct: 756 KKE----EQQRLAERQLQEEQEKKAKEA 779
Score = 45.8 bits (107), Expect = 3e-04
Identities = 44/232 (18%), Positives = 105/232 (45%), Gaps = 10/232 (4%)
Query: 381 EADLKRWEAIREA-------SRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQ 433
E LKR E +R+ +++ +K+ +E+ F +I E K+ + AE+ ++
Sbjct: 565 EVKLKREERLRKVLQARERVEQMKEEKKKQIEQKFAQI-DEKTEKAKEERLAEEKAK-KK 622
Query: 434 LRYEEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSS 493
++M++++++ K++++ + + ++ + + LQKKKEE +E ++A E + +
Sbjct: 623 AAAKKMEEVEARRKQEEEARRLRWLQQEEEERRHQELLQKKKEEEQERLRKAAEAKRLAE 682
Query: 494 KTFKEML-QDRESQNQKSTVPSRRRMYSFDDVLEEGKRPPTMTVSEASYQSERVEEKGAT 552
+ +E Q+R Q ++ + + L E +R +A + + E+
Sbjct: 683 QREQERREQERREQERREQERREQERREQERQLAEQERRREQERLQAERELQEREKALRL 742
Query: 553 YPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSLRSRSTQMES 604
++ +E K E + E QL + + + A S + + ++S
Sbjct: 743 QKEQLQRELEEKKKKEEQQRLAERQLQEEQEKKAKEAAGASKALNVTVDVQS 794
Score = 36.2 bits (82), Expect = 0.22
Identities = 32/135 (23%), Positives = 61/135 (45%), Gaps = 6/135 (4%)
Query: 1060 ERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQKRQAEIERETSVRIYQYRRPVDSYDIP 1119
ER+R + +EE EQ R Q E+++R EE K + E E ++ Q R V+
Sbjct: 534 ERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKRE---ERLRKVLQARERVEQMKEE 590
Query: 1120 KTEEASSGFLPGDRNKSRSTTE-LDDYSTNKNGNNKYLDQIGNMTSSQRRSKKEQVPSGA 1178
K ++ F D ++ E L + K K ++++ + +++ +
Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 650
Query: 1179 ELER--QQILQEMRK 1191
E ER Q++LQ+ ++
Sbjct: 651 EEERRHQELLQKKKE 665
Score = 31.6 bits (70), Expect = 5.5
Identities = 48/261 (18%), Positives = 109/261 (41%), Gaps = 26/261 (9%)
Query: 370 PPISFTPG-PCSEADLKRWEAIREASRLRHKKRLMVE-----RLFQKIYGENGSKSMSDV 423
PP S TP PC + + R +R + ++++ R K + + + D
Sbjct: 473 PPRSKTPSSPCPASKVVR--PLRTFLHTVQRNQMLMTPTSAPRSVMKSFIKRNTPLRMDP 530
Query: 424 SAEDVQNLRQLRY-EEMQKIKSQLKEQDQKWQDDLAKWK--DRRKSYTSDLQKKKEEREE 480
++ Q L LR EE ++++ Q E+D++ + + K K +R + ++ ++ +EE
Sbjct: 531 KEKERQRLENLRRKEEAEQLRRQKVEEDKRRRLEEVKLKREERLRKVLQARERVEQMKEE 590
Query: 481 IEKQALEK----SKRSSKTFKEMLQDRESQNQKST-----VPSRR------RMYSFDDVL 525
+KQ +K +++ K +E L + +++ + + V +RR R +
Sbjct: 591 KKKQIEQKFAQIDEKTEKAKEERLAEEKAKKKAAAKKMEEVEARRKQEEEARRLRWLQQE 650
Query: 526 EEGKRPPTMTVSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVE 585
EE +R + + + ER+ + +E +R ++ E + Q E
Sbjct: 651 EEERRHQELLQKKKEEEQERLRKAAEAKRLAEQREQERREQERREQERREQERREQERRE 710
Query: 586 EQSPASLSSLRSRSTQMESTR 606
++ + R ++++ R
Sbjct: 711 QERQLAEQERRREQERLQAER 731
>gi|156766047 GRB10 interacting GYF protein 2 isoform c [Homo sapiens]
Length = 1293
Score = 61.6 bits (148), Expect = 5e-09
Identities = 55/213 (25%), Positives = 91/213 (42%), Gaps = 31/213 (14%)
Query: 930 PTISAPSRW----VWD----------------QEEERK----RQERWQKEQDRLLQEKYQ 965
PT S P+ W VWD Q E+ K QER + E +E+ +
Sbjct: 690 PTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEER 749
Query: 966 REQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSS 1025
+ QE+LR + + + + E K +EE + +L + E +
Sbjct: 750 KRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQ 809
Query: 1026 DREGTRAGEEERRQPQEEVVHEDQGKKPQDQLV------IERERKWEQ-QLQEEQEQKRL 1078
E R EE RR+ +E E+ +K +++ E +R+ E+ +L+ E+E RL
Sbjct: 810 QEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARL 869
Query: 1079 QAEAEEQKRPAEEQKRQAEIERETSVRIYQYRR 1111
+ E EE+KR E +RQ E+ R+ + RR
Sbjct: 870 RHEEEERKRKELEVQRQKELMRQRQQQQEALRR 902
Score = 58.9 bits (141), Expect = 3e-08
Identities = 69/335 (20%), Positives = 143/335 (42%), Gaps = 32/335 (9%)
Query: 942 QEEERKRQERWQKEQDRLL-----QEKYQREQEKL------------REEWQRAKQEAER 984
+EEERKRQE +++Q+ +L +E+ +RE+E+L RE+ +++ E
Sbjct: 745 EEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREE 804
Query: 985 ENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSK--SSDREGTRAGEEERRQPQE 1042
E + +E L L R E +K + E R EE R + +E
Sbjct: 805 EERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE 864
Query: 1043 EVV---HEDQGKKPQDQLVIERERKWEQQLQEEQEQ-KRLQAEAEEQKRPAEEQKRQAEI 1098
E HE++ +K + +L ++R+++ +Q Q++QE +RLQ + ++Q+ + +
Sbjct: 865 EAARLRHEEEERK-RKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTW 923
Query: 1099 ERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQ 1158
++++ Q + + +I K EE L ++ + + + + + L
Sbjct: 924 GQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSG 982
Query: 1159 IGNMTSSQRRSK---KEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVS 1215
GN++ +K + Q ++++QQ Q+ ++ +N+ ++ N S
Sbjct: 983 WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGN----S 1038
Query: 1216 LPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFY 1250
+ G + G S+ W N GF+
Sbjct: 1039 VWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFW 1073
Score = 47.0 bits (110), Expect = 1e-04
Identities = 58/272 (21%), Positives = 115/272 (42%), Gaps = 35/272 (12%)
Query: 936 SRWVWDQEEERKRQE----RWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLD 991
++W ++EE ++R E R ++E RL E+ +R++++L + Q+ ++ + L
Sbjct: 842 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL- 900
Query: 992 EELMVLSSNSMSLTTREPSLATW-----------EATWS--EGSKSSDREGTRAGEEERR 1038
L + PS +TW +AT S E K + + EE+RR
Sbjct: 901 RRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 960
Query: 1039 QPQEEVVHEDQGKKPQDQLV-----IERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQK 1093
Q +E + Q ++ Q Q + + + + L E Q+++ Q + ++Q++ +Q
Sbjct: 961 QQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQP 1020
Query: 1094 RQAEIERETSVRIYQYRRPVDSYDI-PKTEEAS---SGFLPGDRNKSRSTTELDD----- 1144
+A +++ S + P + AS S K+ + DD
Sbjct: 1021 NRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEV 1080
Query: 1145 ---YSTNKNGNNKYLDQIGNMTSSQRRSKKEQ 1173
STNKN NN L + +++ Q + +E+
Sbjct: 1081 GPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1112
Score = 38.5 bits (88), Expect = 0.045
Identities = 30/121 (24%), Positives = 59/121 (48%), Gaps = 10/121 (8%)
Query: 392 EASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLK-EQD 450
EA+RLRH++ E +K K + + + LR+L+ ++ Q+ +Q+K
Sbjct: 865 EAARLRHEE----EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 920
Query: 451 QKW--QDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQ 508
W Q + + + +++QK +EER E+Q E+ +R + + LQ ++ Q Q
Sbjct: 921 STWGQQSNTTACQSQATLSLAEIQKLEEER---ERQLREEQRRQQRELMKALQQQQQQQQ 977
Query: 509 K 509
+
Sbjct: 978 Q 978
Score = 34.7 bits (78), Expect = 0.65
Identities = 37/200 (18%), Positives = 83/200 (41%), Gaps = 22/200 (11%)
Query: 437 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEE------------REEIE-- 482
++++K K+ EQ+++ + AK ++ + +L++++EE REE E
Sbjct: 721 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 780
Query: 483 ----KQALEKSKRSSKTFKEMLQDRESQNQKST---VPSRRRMYSFDDVLEEGKRPPTMT 535
++AL + + + ++ E Q Q+ + RRR EE R
Sbjct: 781 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 840
Query: 536 VSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSL 595
++ + + E + + + +E + + E+R E+++ Q + Q +L
Sbjct: 841 AAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL 900
Query: 596 RSRSTQMESTRVS-ASLPRS 614
R Q + +++ LP S
Sbjct: 901 RRLQQQQQQQQLAQMKLPSS 920
>gi|156766045 GRB10 interacting GYF protein 2 isoform a [Homo sapiens]
Length = 1320
Score = 61.6 bits (148), Expect = 5e-09
Identities = 55/213 (25%), Positives = 91/213 (42%), Gaps = 31/213 (14%)
Query: 930 PTISAPSRW----VWD----------------QEEERK----RQERWQKEQDRLLQEKYQ 965
PT S P+ W VWD Q E+ K QER + E +E+ +
Sbjct: 717 PTASQPTVWEGGSVWDLPLDTTTPGPALEQLQQLEKAKAAKLEQERREAEMRAKREEEER 776
Query: 966 REQEKLREEWQRAKQEAERENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSKSS 1025
+ QE+LR + + + + E K +EE + +L + E +
Sbjct: 777 KRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREEEERQQ 836
Query: 1026 DREGTRAGEEERRQPQEEVVHEDQGKKPQDQLV------IERERKWEQ-QLQEEQEQKRL 1078
E R EE RR+ +E E+ +K +++ E +R+ E+ +L+ E+E RL
Sbjct: 837 QEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEEEAARL 896
Query: 1079 QAEAEEQKRPAEEQKRQAEIERETSVRIYQYRR 1111
+ E EE+KR E +RQ E+ R+ + RR
Sbjct: 897 RHEEEERKRKELEVQRQKELMRQRQQQQEALRR 929
Score = 58.9 bits (141), Expect = 3e-08
Identities = 69/335 (20%), Positives = 143/335 (42%), Gaps = 32/335 (9%)
Query: 942 QEEERKRQERWQKEQDRLL-----QEKYQREQEKL------------REEWQRAKQEAER 984
+EEERKRQE +++Q+ +L +E+ +RE+E+L RE+ +++ E
Sbjct: 772 EEEERKRQEELRRQQEEILRRQQEEERKRREEEELARRKQEEALRRQREQEIALRRQREE 831
Query: 985 ENSKYLDEELMVLSSNSMSLTTREPSLATWEATWSEGSK--SSDREGTRAGEEERRQPQE 1042
E + +E L L R E +K + E R EE R + +E
Sbjct: 832 EERQQQEEALRRLEERRREEEERRKQEELLRKQEEEAAKWAREEEEAQRRLEENRLRMEE 891
Query: 1043 EVV---HEDQGKKPQDQLVIERERKWEQQLQEEQEQ-KRLQAEAEEQKRPAEEQKRQAEI 1098
E HE++ +K + +L ++R+++ +Q Q++QE +RLQ + ++Q+ + +
Sbjct: 892 EAARLRHEEEERK-RKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSSSTW 950
Query: 1099 ERETSVRIYQYRRPVDSYDIPKTEEASSGFLPGDRNKSRSTTELDDYSTNKNGNNKYLDQ 1158
++++ Q + + +I K EE L ++ + + + + + L
Sbjct: 951 GQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRRQQREL-MKALQQQQQQQQQKLSG 1009
Query: 1159 IGNMTSSQRRSK---KEQVPSGAELERQQILQEMRKRTPLHNDNSWIRQRSASVNKEPVS 1215
GN++ +K + Q ++++QQ Q+ ++ +N+ ++ N S
Sbjct: 1010 WGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQPNRARNNTHSNLHTSIGN----S 1065
Query: 1216 LPGIMRRGESLDNLDSPRSNSWRQPPWLNQPTGFY 1250
+ G + G S+ W N GF+
Sbjct: 1066 VWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFW 1100
Score = 47.0 bits (110), Expect = 1e-04
Identities = 58/272 (21%), Positives = 115/272 (42%), Gaps = 35/272 (12%)
Query: 936 SRWVWDQEEERKRQE----RWQKEQDRLLQEKYQREQEKLREEWQRAKQEAERENSKYLD 991
++W ++EE ++R E R ++E RL E+ +R++++L + Q+ ++ + L
Sbjct: 869 AKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL- 927
Query: 992 EELMVLSSNSMSLTTREPSLATW-----------EATWS--EGSKSSDREGTRAGEEERR 1038
L + PS +TW +AT S E K + + EE+RR
Sbjct: 928 RRLQQQQQQQQLAQMKLPSSSTWGQQSNTTACQSQATLSLAEIQKLEEERERQLREEQRR 987
Query: 1039 QPQEEVVHEDQGKKPQDQLV-----IERERKWEQQLQEEQEQKRLQAEAEEQKRPAEEQK 1093
Q +E + Q ++ Q Q + + + + L E Q+++ Q + ++Q++ +Q
Sbjct: 988 QQRELMKALQQQQQQQQQKLSGWGNVSKPSGTTKSLLEIQQEEARQMQKQQQQQQQHQQP 1047
Query: 1094 RQAEIERETSVRIYQYRRPVDSYDI-PKTEEAS---SGFLPGDRNKSRSTTELDD----- 1144
+A +++ S + P + AS S K+ + DD
Sbjct: 1048 NRARNNTHSNLHTSIGNSVWGSINTGPPNQWASDLVSSIWSNADTKNSNMGFWDDAVKEV 1107
Query: 1145 ---YSTNKNGNNKYLDQIGNMTSSQRRSKKEQ 1173
STNKN NN L + +++ Q + +E+
Sbjct: 1108 GPRNSTNKNKNNASLSKSVGVSNRQNKKVEEE 1139
Score = 38.5 bits (88), Expect = 0.045
Identities = 30/121 (24%), Positives = 59/121 (48%), Gaps = 10/121 (8%)
Query: 392 EASRLRHKKRLMVERLFQKIYGENGSKSMSDVSAEDVQNLRQLRYEEMQKIKSQLK-EQD 450
EA+RLRH++ E +K K + + + LR+L+ ++ Q+ +Q+K
Sbjct: 892 EAARLRHEE----EERKRKELEVQRQKELMRQRQQQQEALRRLQQQQQQQQLAQMKLPSS 947
Query: 451 QKW--QDDLAKWKDRRKSYTSDLQKKKEEREEIEKQALEKSKRSSKTFKEMLQDRESQNQ 508
W Q + + + +++QK +EER E+Q E+ +R + + LQ ++ Q Q
Sbjct: 948 STWGQQSNTTACQSQATLSLAEIQKLEEER---ERQLREEQRRQQRELMKALQQQQQQQQ 1004
Query: 509 K 509
+
Sbjct: 1005 Q 1005
Score = 34.7 bits (78), Expect = 0.65
Identities = 37/200 (18%), Positives = 83/200 (41%), Gaps = 22/200 (11%)
Query: 437 EEMQKIKSQLKEQDQKWQDDLAKWKDRRKSYTSDLQKKKEE------------REEIE-- 482
++++K K+ EQ+++ + AK ++ + +L++++EE REE E
Sbjct: 748 QQLEKAKAAKLEQERREAEMRAKREEEERKRQEELRRQQEEILRRQQEEERKRREEEELA 807
Query: 483 ----KQALEKSKRSSKTFKEMLQDRESQNQKST---VPSRRRMYSFDDVLEEGKRPPTMT 535
++AL + + + ++ E Q Q+ + RRR EE R
Sbjct: 808 RRKQEEALRRQREQEIALRRQREEEERQQQEEALRRLEERRREEEERRKQEELLRKQEEE 867
Query: 536 VSEASYQSERVEEKGATYPSEIPKEDSTTFAKREDRVTTEIQLPSQSPVEEQSPASLSSL 595
++ + + E + + + +E + + E+R E+++ Q + Q +L
Sbjct: 868 AAKWAREEEEAQRRLEENRLRMEEEAARLRHEEEERKRKELEVQRQKELMRQRQQQQEAL 927
Query: 596 RSRSTQMESTRVS-ASLPRS 614
R Q + +++ LP S
Sbjct: 928 RRLQQQQQQQQLAQMKLPSS 947
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.309 0.125 0.355
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 57,063,228
Number of Sequences: 37866
Number of extensions: 2962602
Number of successful extensions: 40884
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 355
Number of HSP's successfully gapped in prelim test: 1224
Number of HSP's that attempted gapping in prelim test: 17114
Number of HSP's gapped (non-prelim): 11636
length of query: 1385
length of database: 18,247,518
effective HSP length: 115
effective length of query: 1270
effective length of database: 13,892,928
effective search space: 17644018560
effective search space used: 17644018560
T: 11
A: 40
X1: 16 ( 7.1 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 42 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.