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Search of human proteins with 221316630
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|221316630 coatomer protein complex, subunit beta 1 [Homo
sapiens]
(953 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|221316632 coatomer protein complex, subunit beta 1 [Homo sapi... 1863 0.0
gi|221316630 coatomer protein complex, subunit beta 1 [Homo sapi... 1863 0.0
gi|7705369 coatomer protein complex, subunit beta 1 [Homo sapiens] 1863 0.0
gi|22027651 adaptor-related protein complex 1 beta 1 subunit iso... 85 3e-16
gi|22027653 adaptor-related protein complex 1 beta 1 subunit iso... 85 3e-16
gi|117553580 adaptor-related protein complex 3, delta 1 subunit ... 83 1e-15
gi|71773106 adaptor-related protein complex 2, beta 1 subunit is... 79 2e-14
gi|4557469 adaptor-related protein complex 2, beta 1 subunit iso... 79 2e-14
gi|34482047 adaptor-related protein complex 3, beta 2 subunit [H... 69 3e-11
gi|32484979 adaptor-related protein complex 3, beta 1 subunit [H... 67 6e-11
gi|37675283 adaptor-related protein complex 4, epsilon 1 subunit... 60 7e-09
gi|71773010 adaptor-related protein complex 1, gamma 1 subunit i... 55 3e-07
gi|71772942 adaptor-related protein complex 1, gamma 1 subunit i... 54 7e-07
gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [H... 50 1e-05
gi|166197671 adaptor-related protein complex 4, beta 1 subunit [... 44 7e-04
gi|109134349 coatomer protein complex, subunit gamma 2 [Homo sap... 37 0.067
gi|11559929 coatomer protein complex, subunit gamma 1 [Homo sapi... 36 0.15
gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens] 35 0.44
gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens] 34 0.57
gi|95147555 microtubule-associated protein 1A [Homo sapiens] 34 0.74
gi|64085252 hypothetical protein LOC145508 [Homo sapiens] 34 0.74
gi|239744625 PREDICTED: hypothetical protein XP_002343208 [Homo ... 33 0.97
gi|127138957 zinc finger protein 537 [Homo sapiens] 33 0.97
gi|109659847 filamin A interacting protein 1-like isoform 3 [Hom... 33 1.3
gi|109659849 filamin A interacting protein 1-like isoform 2 [Hom... 33 1.3
gi|109659845 filamin A interacting protein 1-like isoform 1 [Hom... 33 1.3
gi|71061468 centromere protein E [Homo sapiens] 33 1.3
gi|19923599 calmin [Homo sapiens] 33 1.3
gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1 ... 33 1.7
gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2 [... 33 1.7
>gi|221316632 coatomer protein complex, subunit beta 1 [Homo
sapiens]
Length = 953
Score = 1863 bits (4827), Expect = 0.0
Identities = 953/953 (100%), Positives = 953/953 (100%)
Query: 1 MTAAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLM 60
MTAAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLM
Sbjct: 1 MTAAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLM 60
Query: 61 TIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGST 120
TIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGST
Sbjct: 61 TIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGST 120
Query: 121 LRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDF 180
LRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDF
Sbjct: 121 LRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDF 180
Query: 181 LVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPS 240
LVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPS
Sbjct: 181 LVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPS 240
Query: 241 ERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLI 300
ERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLI
Sbjct: 241 ERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLI 300
Query: 301 VLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVL 360
VLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVL
Sbjct: 301 VLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVL 360
Query: 361 KKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADV 420
KKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADV
Sbjct: 361 KKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADV 420
Query: 421 LEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEIR 480
LEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEIR
Sbjct: 421 LEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEIR 480
Query: 481 RSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSALSSSRPTKKEEDRP 540
RSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSALSSSRPTKKEEDRP
Sbjct: 481 RSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSALSSSRPTKKEEDRP 540
Query: 541 PLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSL 600
PLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSL
Sbjct: 541 PLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSL 600
Query: 601 PKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEK 660
PKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEK
Sbjct: 601 PKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEK 660
Query: 661 RNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKVTQLT 720
RNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKVTQLT
Sbjct: 661 RNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKVTQLT 720
Query: 721 GFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPH 780
GFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPH
Sbjct: 721 GFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPH 780
Query: 781 DFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEF 840
DFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEF
Sbjct: 781 DFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEF 840
Query: 841 RQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCLTPEKALSGYCGFMAANLYARSI 900
RQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCLTPEKALSGYCGFMAANLYARSI
Sbjct: 841 RQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCLTPEKALSGYCGFMAANLYARSI 900
Query: 901 FGEDALANVSIEKPIHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSI 953
FGEDALANVSIEKPIHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSI
Sbjct: 901 FGEDALANVSIEKPIHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSI 953
>gi|221316630 coatomer protein complex, subunit beta 1 [Homo
sapiens]
Length = 953
Score = 1863 bits (4827), Expect = 0.0
Identities = 953/953 (100%), Positives = 953/953 (100%)
Query: 1 MTAAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLM 60
MTAAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLM
Sbjct: 1 MTAAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLM 60
Query: 61 TIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGST 120
TIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGST
Sbjct: 61 TIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGST 120
Query: 121 LRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDF 180
LRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDF
Sbjct: 121 LRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDF 180
Query: 181 LVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPS 240
LVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPS
Sbjct: 181 LVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPS 240
Query: 241 ERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLI 300
ERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLI
Sbjct: 241 ERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLI 300
Query: 301 VLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVL 360
VLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVL
Sbjct: 301 VLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVL 360
Query: 361 KKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADV 420
KKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADV
Sbjct: 361 KKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADV 420
Query: 421 LEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEIR 480
LEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEIR
Sbjct: 421 LEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEIR 480
Query: 481 RSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSALSSSRPTKKEEDRP 540
RSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSALSSSRPTKKEEDRP
Sbjct: 481 RSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSALSSSRPTKKEEDRP 540
Query: 541 PLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSL 600
PLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSL
Sbjct: 541 PLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSL 600
Query: 601 PKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEK 660
PKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEK
Sbjct: 601 PKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEK 660
Query: 661 RNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKVTQLT 720
RNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKVTQLT
Sbjct: 661 RNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKVTQLT 720
Query: 721 GFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPH 780
GFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPH
Sbjct: 721 GFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPH 780
Query: 781 DFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEF 840
DFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEF
Sbjct: 781 DFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEF 840
Query: 841 RQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCLTPEKALSGYCGFMAANLYARSI 900
RQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCLTPEKALSGYCGFMAANLYARSI
Sbjct: 841 RQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCLTPEKALSGYCGFMAANLYARSI 900
Query: 901 FGEDALANVSIEKPIHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSI 953
FGEDALANVSIEKPIHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSI
Sbjct: 901 FGEDALANVSIEKPIHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSI 953
>gi|7705369 coatomer protein complex, subunit beta 1 [Homo sapiens]
Length = 953
Score = 1863 bits (4827), Expect = 0.0
Identities = 953/953 (100%), Positives = 953/953 (100%)
Query: 1 MTAAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLM 60
MTAAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLM
Sbjct: 1 MTAAENVCYTLINVPMDSEPPSEISLKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLM 60
Query: 61 TIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGST 120
TIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGST
Sbjct: 61 TIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGST 120
Query: 121 LRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDF 180
LRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDF
Sbjct: 121 LRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDF 180
Query: 181 LVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPS 240
LVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPS
Sbjct: 181 LVNEKDASCKRNAFMMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPS 240
Query: 241 ERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLI 300
ERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLI
Sbjct: 241 ERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLI 300
Query: 301 VLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVL 360
VLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVL
Sbjct: 301 VLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVL 360
Query: 361 KKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADV 420
KKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADV
Sbjct: 361 KKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADV 420
Query: 421 LEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEIR 480
LEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEIR
Sbjct: 421 LEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKEDIQSVMTEIR 480
Query: 481 RSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSALSSSRPTKKEEDRP 540
RSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSALSSSRPTKKEEDRP
Sbjct: 481 RSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSALSSSRPTKKEEDRP 540
Query: 541 PLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSL 600
PLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSL
Sbjct: 541 PLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSL 600
Query: 601 PKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEK 660
PKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEK
Sbjct: 601 PKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEK 660
Query: 661 RNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKVTQLT 720
RNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKVTQLT
Sbjct: 661 RNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKVTQLT 720
Query: 721 GFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPH 780
GFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPH
Sbjct: 721 GFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAPH 780
Query: 781 DFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEF 840
DFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEF
Sbjct: 781 DFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLSDIHIDIMDYIQPATCTDAEF 840
Query: 841 RQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCLTPEKALSGYCGFMAANLYARSI 900
RQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCLTPEKALSGYCGFMAANLYARSI
Sbjct: 841 RQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCLTPEKALSGYCGFMAANLYARSI 900
Query: 901 FGEDALANVSIEKPIHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSI 953
FGEDALANVSIEKPIHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSI
Sbjct: 901 FGEDALANVSIEKPIHQGPDAAVTGHIRIRAKSQGMALSLGDKINLSQKKTSI 953
>gi|22027651 adaptor-related protein complex 1 beta 1 subunit
isoform a [Homo sapiens]
Length = 949
Score = 85.1 bits (209), Expect = 3e-16
Identities = 120/620 (19%), Positives = 250/620 (40%), Gaps = 101/620 (16%)
Query: 26 LKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIV 85
LK +L + K EA+KKVI + G+ + L ++ + + +KKL+ ++
Sbjct: 18 LKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVN-CMQTDNLELKKLVYLYLMNY 76
Query: 86 PKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLE 145
K+ PD I+ + + KD + PN IR +R + ++ ++ E L +R CL+
Sbjct: 77 AKSQPD-----MAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLK 131
Query: 146 HRHSYVRRNAVLAIYTIYRNFEHLIPDAP--ELIHDFLVNEKDASCKRNAFMMLIHADQD 203
YVR+ A + + ++ L+ D + + D L+++ + NA L +
Sbjct: 132 DEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKD-LISDSNPMVVANAVAALSEIAES 190
Query: 204 -----------RALDYLSTCIDQVQTFGDIL----------------QLVIVELIYKVCH 236
++++ L T +++ +G I Q + + ++ H
Sbjct: 191 HPSSNLLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDREAQSICERVTPRLSH 250
Query: 237 ANPSERARFIRCIYNLLQSSSPAVKY------EAAGTLVTLSSAPTAIKAAAQCYIDLII 290
AN + ++ + ++ S + Y + A LVTL SA ++ A I+LI+
Sbjct: 251 ANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLKKLAPPLVTLLSAEPELQYVALRNINLIV 310
Query: 291 KESDNNVKLIVLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSS 350
++ +K HE M + V + V+ + L + + L S
Sbjct: 311 QKRPEILK---------------HE-------MKVFFVKYNDPIYVKLEKLDIMIRLASQ 348
Query: 351 RNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLS 410
N+ +++ LK+ + D D R+ VR + C+++ A + L++ +
Sbjct: 349 ANIAQVLAELKEYATEV-------DVDFVRK-AVRAIGRCAIKVEQSAERCVSTLLDLIQ 400
Query: 411 DNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKE 470
+ + +++ +++ N ++ + E ++ + +WI+GEY +
Sbjct: 401 TKVNYVVQEAIVVIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEYAERID 460
Query: 471 DIQSVMTEIRRSL-GEIPIVESEIKKEAGEL---KPEEEITVGPVQKLVTEMGTYATQSA 526
+ ++ E V+ ++ +L KP E Q+LV ++ + ATQ
Sbjct: 461 NADELLESFLEGFHDESTQVQLQLLTAIVKLFLKKPTE------TQELVQQVLSLATQ-- 512
Query: 527 LSSSRPTKKEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKK-KQNSFVAEA 585
+ D P LR D + L+T +A + V L ++ + + + E
Sbjct: 513 ---------DSDNPDLR----DRGYIYWRLLST--DPVAAKEVVLAEKPLISEETDLIEP 557
Query: 586 MLLMATILHLGK-SSLPKKP 604
LL I ++G +S+ KP
Sbjct: 558 TLLDELICYIGTLASVYHKP 577
>gi|22027653 adaptor-related protein complex 1 beta 1 subunit
isoform b [Homo sapiens]
Length = 942
Score = 85.1 bits (209), Expect = 3e-16
Identities = 120/620 (19%), Positives = 250/620 (40%), Gaps = 101/620 (16%)
Query: 26 LKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIV 85
LK +L + K EA+KKVI + G+ + L ++ + + +KKL+ ++
Sbjct: 18 LKAELNSDKKEKKKEAVKKVIASMTVGKDVSALFPDVVN-CMQTDNLELKKLVYLYLMNY 76
Query: 86 PKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLE 145
K+ PD I+ + + KD + PN IR +R + ++ ++ E L +R CL+
Sbjct: 77 AKSQPD-----MAIMAVNTFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLK 131
Query: 146 HRHSYVRRNAVLAIYTIYRNFEHLIPDAP--ELIHDFLVNEKDASCKRNAFMMLIHADQD 203
YVR+ A + + ++ L+ D + + D L+++ + NA L +
Sbjct: 132 DEDPYVRKTAAVCVAKLHDINAQLVEDQGFLDTLKD-LISDSNPMVVANAVAALSEIAES 190
Query: 204 -----------RALDYLSTCIDQVQTFGDIL----------------QLVIVELIYKVCH 236
++++ L T +++ +G I Q + + ++ H
Sbjct: 191 HPSSNLLDLNPQSINKLLTALNECTEWGQIFILDCLANYMPKDDREAQSICERVTPRLSH 250
Query: 237 ANPSERARFIRCIYNLLQSSSPAVKY------EAAGTLVTLSSAPTAIKAAAQCYIDLII 290
AN + ++ + ++ S + Y + A LVTL SA ++ A I+LI+
Sbjct: 251 ANSAVVLSAVKVLMKFMEMLSKDLDYYGTLLKKLAPPLVTLLSAEPELQYVALRNINLIV 310
Query: 291 KESDNNVKLIVLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSS 350
++ +K HE M + V + V+ + L + + L S
Sbjct: 311 QKRPEILK---------------HE-------MKVFFVKYNDPIYVKLEKLDIMIRLASQ 348
Query: 351 RNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLS 410
N+ +++ LK+ + D D R+ VR + C+++ A + L++ +
Sbjct: 349 ANIAQVLAELKEYATEV-------DVDFVRK-AVRAIGRCAIKVEQSAERCVSTLLDLIQ 400
Query: 411 DNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYCSTKE 470
+ + +++ +++ N ++ + E ++ + +WI+GEY +
Sbjct: 401 TKVNYVVQEAIVVIKDIFRKYPNKYESVIATLCENLDSLDEPEARAAMIWIVGEYAERID 460
Query: 471 DIQSVMTEIRRSL-GEIPIVESEIKKEAGEL---KPEEEITVGPVQKLVTEMGTYATQSA 526
+ ++ E V+ ++ +L KP E Q+LV ++ + ATQ
Sbjct: 461 NADELLESFLEGFHDESTQVQLQLLTAIVKLFLKKPTE------TQELVQQVLSLATQ-- 512
Query: 527 LSSSRPTKKEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKK-KQNSFVAEA 585
+ D P LR D + L+T +A + V L ++ + + + E
Sbjct: 513 ---------DSDNPDLR----DRGYIYWRLLST--DPVAAKEVVLAEKPLISEETDLIEP 557
Query: 586 MLLMATILHLGK-SSLPKKP 604
LL I ++G +S+ KP
Sbjct: 558 TLLDELICYIGTLASVYHKP 577
>gi|117553580 adaptor-related protein complex 3, delta 1 subunit
isoform 2 [Homo sapiens]
Length = 1153
Score = 82.8 bits (203), Expect = 1e-15
Identities = 121/534 (22%), Positives = 226/534 (42%), Gaps = 65/534 (12%)
Query: 26 LKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIV 85
+K +L++ ++ K A+ K+ + + G + II V+ T K++ +
Sbjct: 43 IKQELKQDNIAVKANAVCKLTYLQMLGYDISWAAFNIIE-VMSASKFTFKRIGYL----- 96
Query: 86 PKTTPDGRLLHE----MILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIR 141
+ HE ++L + RKDL P+++ G L L +L L I
Sbjct: 97 ----AASQSFHEGTDVIMLTTNQIRKDLSSPSQYDTGVALTGLSCFVTPDLARDLANDIM 152
Query: 142 ACLEHRHSYVRRNAVLAIYTIYRNF-EHLIPDAPELIHDFLVNEKDASCKRNAFMMLIHA 200
+ H Y+R+ AVL +Y ++ + E L P P L + + D + A ++
Sbjct: 153 TLMSHTKPYIRKKAVLIMYKVFLKYPESLRPAFPRLKEK--LEDPDPGVQSAAVNVICEL 210
Query: 201 DQDRALDYLSTC----IDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYNLLQSS 256
+ +YLS + + + + I++L + P + I + NL+ S+
Sbjct: 211 ARRNPKNYLSLAPLFFKLMTSSTNNWVLIKIIKLFGALTPLEPRLGKKLIEPLTNLIHST 270
Query: 257 SP-AVKYEAAGT----LVTLSSAPTAIKAAAQCYID---LIIKESDNNVKLIVLDRLIE- 307
S ++ YE T L++LSS A+ Q + ++I++SD N+K + L + +
Sbjct: 271 SAMSLLYECVNTVIAVLISLSSGMPNHSASIQLCVQKLRILIEDSDQNLKYLGLLAMSKI 330
Query: 308 LKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKT 367
LK HP + +DL IL+ L D +R + L L +VS +N+ E+V L V K
Sbjct: 331 LKTHPKSVQSHKDL---ILQCLDDKDESIRLRALDLLYGMVSKKNLMEIVKKLMTHVDKA 387
Query: 368 NNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAAN---VIPVLMEFL----SDNNEAAAADV 420
E T +LL + + CS N I +L+E + + AA +
Sbjct: 388 ------EGTTYRDELLTKIIDICSQSNYQYITNFEWYISILVELTRLEGTRHGHLIAAQM 441
Query: 421 LEFV--REAIQRFDNLRMLIVEKMLEVFHAIKS-------VKIYRGALWILGEYCS-TKE 470
L+ +AI++F +M +L+ H + S ++ A WI GE+ +E
Sbjct: 442 LDVAIRVKAIRKFAVSQM---SALLDSAHLLASSTQRNGICEVLYAAAWICGEFSEHLQE 498
Query: 471 DIQSVMTEIRRSLGEIP------IVESEIKKEAGELKPEEEITVGPVQKLVTEM 518
++ +R + +P V++ +K A L+ +E+ + VT++
Sbjct: 499 PHHTLEAMLRPRVTTLPGHIQAVYVQNVVKLYASILQQKEQAGEAEGAQAVTQL 552
>gi|71773106 adaptor-related protein complex 2, beta 1 subunit
isoform a [Homo sapiens]
Length = 951
Score = 79.0 bits (193), Expect = 2e-14
Identities = 122/622 (19%), Positives = 244/622 (39%), Gaps = 105/622 (16%)
Query: 26 LKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIV 85
LK +L + + EA+KKVI + G+ + L ++ + + +KKL+ ++
Sbjct: 18 LKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVN-CMQTDNLELKKLVYLYLMNY 76
Query: 86 PKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLE 145
K+ PD I+ +++ KD + PN IR +R + ++ ++ E L +R CL+
Sbjct: 77 AKSQPD-----MAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLK 131
Query: 146 HRHSYVRRNAVLAIYTIYRNFEHLIPDAPEL--IHDFLVNEKDASCKRNAFMMLIHADQD 203
YVR+ A + + ++ ++ D L + D L+ + + NA L +
Sbjct: 132 DEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRD-LIADSNPMVVANAVAALSEISES 190
Query: 204 -----------RALDYLSTCIDQVQTFGDIL----------------QLVIVELIYKVCH 236
+ ++ L T +++ +G I Q + + ++ H
Sbjct: 191 HPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSH 250
Query: 237 ANPSERARFIRCIYNLLQSSSPAVKY------EAAGTLVTLSSAPTAIKAAAQCYIDLII 290
AN + ++ + L+ Y + A LVTL S ++ Y+ L
Sbjct: 251 ANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQ-----YVAL-- 303
Query: 291 KESDNNVKLIVLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSS 350
N+ LIV R LK+ + + V + V+ + L + + L S
Sbjct: 304 ----RNINLIVQKRPEILKQE-----------IKVFFVKYNDPIYVKLEKLDIMIRLASQ 348
Query: 351 RNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLS 410
N+ +++ LK+ + D D R+ VR + C+++ A + L++ +
Sbjct: 349 ANIAQVLAELKEYATEV-------DVDFVRK-AVRAIGRCAIKVEQSAERCVSTLLDLIQ 400
Query: 411 DNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYC---- 466
+ + +R+ +++ N I+ + E ++ +WI+GEY
Sbjct: 401 TKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERID 460
Query: 467 STKEDIQSVMTEIRRSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSA 526
+ E ++S + ++ + + KP E Q+LV ++ + ATQ
Sbjct: 461 NADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSE------TQELVQQVLSLATQ-- 512
Query: 527 LSSSRPTKKEEDRPPLRGFLLDGDFFVAASLAT---TLTKIALRYVALVQEKKKQNSFVA 583
+ D P LR D + L+T T ++ L L+ E+ + +
Sbjct: 513 ---------DSDNPDLR----DRGYIYWRLLSTDPVTAKEVVLSEKPLISEE----TDLI 555
Query: 584 EAMLLMATILHLGK-SSLPKKP 604
E LL I H+G +S+ KP
Sbjct: 556 EPTLLDELICHIGSLASVYHKP 577
>gi|4557469 adaptor-related protein complex 2, beta 1 subunit
isoform b [Homo sapiens]
Length = 937
Score = 79.0 bits (193), Expect = 2e-14
Identities = 122/622 (19%), Positives = 244/622 (39%), Gaps = 105/622 (16%)
Query: 26 LKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIV 85
LK +L + + EA+KKVI + G+ + L ++ + + +KKL+ ++
Sbjct: 18 LKAELNNEKKEKRKEAVKKVIAAMTVGKDVSSLFPDVVN-CMQTDNLELKKLVYLYLMNY 76
Query: 86 PKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLE 145
K+ PD I+ +++ KD + PN IR +R + ++ ++ E L +R CL+
Sbjct: 77 AKSQPD-----MAIMAVNSFVKDCEDPNPLIRALAVRTMGCIRVDKITEYLCEPLRKCLK 131
Query: 146 HRHSYVRRNAVLAIYTIYRNFEHLIPDAPEL--IHDFLVNEKDASCKRNAFMMLIHADQD 203
YVR+ A + + ++ ++ D L + D L+ + + NA L +
Sbjct: 132 DEDPYVRKTAAVCVAKLHDINAQMVEDQGFLDSLRD-LIADSNPMVVANAVAALSEISES 190
Query: 204 -----------RALDYLSTCIDQVQTFGDIL----------------QLVIVELIYKVCH 236
+ ++ L T +++ +G I Q + + ++ H
Sbjct: 191 HPNSNLLDLNPQNINKLLTALNECTEWGQIFILDCLSNYNPKDDREAQSICERVTPRLSH 250
Query: 237 ANPSERARFIRCIYNLLQSSSPAVKY------EAAGTLVTLSSAPTAIKAAAQCYIDLII 290
AN + ++ + L+ Y + A LVTL S ++ Y+ L
Sbjct: 251 ANSAVVLSAVKVLMKFLELLPKDSDYYNMLLKKLAPPLVTLLSGEPEVQ-----YVAL-- 303
Query: 291 KESDNNVKLIVLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSS 350
N+ LIV R LK+ + + V + V+ + L + + L S
Sbjct: 304 ----RNINLIVQKRPEILKQE-----------IKVFFVKYNDPIYVKLEKLDIMIRLASQ 348
Query: 351 RNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLS 410
N+ +++ LK+ + D D R+ VR + C+++ A + L++ +
Sbjct: 349 ANIAQVLAELKEYATEV-------DVDFVRK-AVRAIGRCAIKVEQSAERCVSTLLDLIQ 400
Query: 411 DNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALWILGEYC---- 466
+ + +R+ +++ N I+ + E ++ +WI+GEY
Sbjct: 401 TKVNYVVQEAIVVIRDIFRKYPNKYESIIATLCENLDSLDEPDARAAMIWIVGEYAERID 460
Query: 467 STKEDIQSVMTEIRRSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSA 526
+ E ++S + ++ + + KP E Q+LV ++ + ATQ
Sbjct: 461 NADELLESFLEGFHDESTQVQLTLLTAIVKLFLKKPSE------TQELVQQVLSLATQ-- 512
Query: 527 LSSSRPTKKEEDRPPLRGFLLDGDFFVAASLAT---TLTKIALRYVALVQEKKKQNSFVA 583
+ D P LR D + L+T T ++ L L+ E+ + +
Sbjct: 513 ---------DSDNPDLR----DRGYIYWRLLSTDPVTAKEVVLSEKPLISEE----TDLI 555
Query: 584 EAMLLMATILHLGK-SSLPKKP 604
E LL I H+G +S+ KP
Sbjct: 556 EPTLLDELICHIGSLASVYHKP 577
>gi|34482047 adaptor-related protein complex 3, beta 2 subunit [Homo
sapiens]
Length = 1082
Score = 68.6 bits (166), Expect = 3e-11
Identities = 101/548 (18%), Positives = 210/548 (38%), Gaps = 84/548 (15%)
Query: 26 LKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIV 85
LK L+ K EA+K+++ MI G+ L +++ V ++ +KKL+ V+
Sbjct: 42 LKEMLDTNKDSLKLEAMKRIVAMIARGKNASDLFPAVVKNVA-CKNIEVKKLVYVYLVRY 100
Query: 86 PKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLE 145
+ D LL +++ L+ PN+ IR S LR L ++ ++ +M AI+
Sbjct: 101 AEEQQDLALLS-----ISTFQRGLKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEAAS 155
Query: 146 HRHSYVRRNAVLAIYTIY-----------RNFEHLIPDAPELIHDFLVNEKDASCKRNAF 194
YVR+ A AI +Y E L+ D L+ +V + C
Sbjct: 156 DMSPYVRKTAAHAIPKLYSLDSDQKDQLIEVIEKLLADKTTLVAGSVVMAFEEVCPER-- 213
Query: 195 MMLIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFI-----RCI 249
+ LIH + + L + V+ +G ++ + ++ + +P++ + +
Sbjct: 214 IDLIHKNYRK----LCNLLIDVEEWGQVVIISMLTRYARTQFLSPTQNESLLEENAEKAF 269
Query: 250 YNLLQSSSPAVKYEAAGTLVTLSSAP-----------------------TAIKAAAQCYI 286
Y + + E S P + A AQ Y
Sbjct: 270 YGSEEDEAKGAGSEETAAAAAPSRKPYVMDPDHRLLLRNTKPLLQSRSAAVVMAVAQLYF 329
Query: 287 DLIIK--------------ESDNNVKLIVLDRL--IELKEHPAHERVLQDLVMDILRVLS 330
L K S + V+ +VL + + +K E L+ + S
Sbjct: 330 HLAPKAEVGVIAKALVRLLRSHSEVQYVVLQNVATMSIKRRGMFEPYLKSFY-----IRS 384
Query: 331 TPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSC 390
T +++ L++ +L + N+ ++ +T S +D + ++ + C
Sbjct: 385 TDPTQIKILKLEVLTNLANETNIPTVL-----REFQTYIRSMDKD---FVAATIQAIGRC 436
Query: 391 SVRFPDMAANVIPVLMEFLSDNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIK 450
+ + + L++ LS+ +E A+ + +++ +Q I++ + ++ I+
Sbjct: 437 ATNIGRVRDTCLNGLVQLLSNRDELVVAESVVVIKKLLQMQPAQHGEIIKHLAKLTDNIQ 496
Query: 451 SVKIYRGALWILGEYCSTKEDIQSVMTEIRRSLGEIPIVESEI-KKEAGELKPEEEITVG 509
LW++GEYC E + + ++ R + + E +I K + L + +T
Sbjct: 497 VPMARASILWLIGEYC---EHVPRIAPDVLRKMAKSFTAEEDIVKLQVINLAAKLYLTNS 553
Query: 510 PVQKLVTE 517
KL+T+
Sbjct: 554 KQTKLLTQ 561
>gi|32484979 adaptor-related protein complex 3, beta 1 subunit [Homo
sapiens]
Length = 1094
Score = 67.4 bits (163), Expect = 6e-11
Identities = 102/518 (19%), Positives = 203/518 (39%), Gaps = 79/518 (15%)
Query: 26 LKNDLEKGDVKSKTEALKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIV 85
LK LE +K +A+K+++ MI G+ L +++ V ++ IKKL+ V+
Sbjct: 47 LKQMLESNKDSAKLDAMKRIVGMIAKGKNASELFPAVVKNVAS-KNIEIKKLVYVYLVRY 105
Query: 86 PKTTPDGRLLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLE 145
+ D LL +++ L+ PN+ IR S LR L ++ ++ +M AI+
Sbjct: 106 AEEQQDLALLS-----ISTFQRALKDPNQLIRASALRVLSSIRVPIIVPIMMLAIKEASA 160
Query: 146 HRHSYVRRNAVLAIYTIYRNFEHLIPDAPELIHDF---LVNEKDASCKRNAFMMLIHADQ 202
YVR+NA AI +Y L P+ E++ + L+ +K + M
Sbjct: 161 DLSPYVRKNAAHAIQKLY----SLDPEQKEMLIEVIEKLLKDKSTLVAGSVVMAFEEVCP 216
Query: 203 DRA----LDYLSTC--IDQVQTFGDILQLVIVELIYKVCHA------------------- 237
DR +Y C + V+ +G Q+VI+ ++ +
Sbjct: 217 DRIDLIHKNYRKLCNLLVDVEEWG---QVVIIHMLTRYARTQFVSPWKEGDELEDNGKNF 273
Query: 238 --------------------NPSERARFIRCIYNLLQSSSPAVKYEAAGTLVTLSSAPTA 277
+P R IR LLQS + AV A L S +
Sbjct: 274 YESDDDQKEKTDKKKKPYTMDPDHRL-LIRNTKPLLQSRNAAV-VMAVAQLYWHISPKSE 331
Query: 278 IKAAAQCYIDLIIKESDNNVKLIVLDRLIELKEHPAHERVLQDLVMDILRVLSTPDLEVR 337
++ + L+ S+ V+ IVL + + + + + + V ST ++
Sbjct: 332 AGIISKSLVRLL--RSNREVQYIVLQNIATMS---IQRKGMFEPYLKSFYVRSTDPTMIK 386
Query: 338 KKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDM 397
L++ +L + N+ L+ + V ++ ++T+ C+ ++
Sbjct: 387 TLKLEILTNLANEANISTLLREFQTYV--------KSQDKQFAAATIQTIGRCATNILEV 438
Query: 398 AANVIPVLMEFLSDNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRG 457
+ L+ LS+ +E A+ + +++ +Q I++ M ++ +I
Sbjct: 439 TDTCLNGLVCLLSNRDEIVVAESVVVIKKLLQMQPAQHGEIIKHMAKLLDSITVPVARAS 498
Query: 458 ALWILGEYCSTKEDIQSVMTEIRRSLGEIPIVESEIKK 495
LW++GE C E + + ++ R + + E ++ K
Sbjct: 499 ILWLIGENC---ERVPKIAPDVLRKMAKSFTSEDDLVK 533
>gi|37675283 adaptor-related protein complex 4, epsilon 1 subunit
[Homo sapiens]
Length = 1137
Score = 60.5 bits (145), Expect = 7e-09
Identities = 102/445 (22%), Positives = 186/445 (41%), Gaps = 83/445 (18%)
Query: 95 LHE----MILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSY 150
LHE ++L+ + KDLQ N L + ++ E++ ++P I L+H
Sbjct: 124 LHESHELLLLLVNTVVKDLQSTNLVEVCMALTVVSQIFPCEMIPAVLPLIEDKLQHSKEI 183
Query: 151 VRRNAVLAIYTIYRNFEHLIPDAPELIHDFLVNEKDASCKRNAFMML--IHADQDRALDY 208
VRR AVLA+Y HLI AP + + + A C R+ +M +H +
Sbjct: 184 VRRKAVLALYKF-----HLI--APNQVQHIHIKFRKALCDRDVGVMAASLHIYLRMIKEN 236
Query: 209 LSTCIDQVQTFGDILQLVI-----VELIYKVCHANPS----------------ERARFIR 247
S D +F IL+ V+ VE Y H+ P+ + R
Sbjct: 237 SSGYKDLTGSFVTILKQVVGGKLPVEFNY---HSVPAPWLQIQLLRILGLLGKDDQRTSE 293
Query: 248 CIYNLLQSS----------SPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNV 297
+Y++L S + A+ +E T+ ++ ++ AA+C I + N+
Sbjct: 294 LMYDVLDESLRRAELNHNVTYAILFECVHTVYSIYPKSELLEKAAKC-IGKFVLSPKINL 352
Query: 298 KLIVLDRL-IELKEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEEL 356
K + L L +++ P Q M I+ L PD ++++TL+L + +++N+ +
Sbjct: 353 KYLGLKALTYVIQQDPTLALQHQ---MTIIECLDHPDPIIKRETLELLYRITNAQNITVI 409
Query: 357 VIVL-------KKEVIKTNNVSE-HEDTDKY---RQLLVRTLHSC-----SVRFPDMAAN 400
V + K+E + N V + E +KY ++T+++ V PD+ N
Sbjct: 410 VQKMLEYLHQSKEEYVIVNLVGKIAELAEKYAPDNAWFIQTMNAVFSVGGDVMHPDIPNN 469
Query: 401 VIPVLMEFLSDNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIYRGALW 460
+ +L E D E + A+Q + L + M VF+ + +++ W
Sbjct: 470 FLRLLAEGFDDETEDQQLRLY-----AVQSY-----LTLLDMENVFYPQRFLQVMS---W 516
Query: 461 ILGE--YCSTKEDIQSVMTEIRRSL 483
+LGE Y KE + V+ ++ + L
Sbjct: 517 VLGEYSYLLDKETPEEVIAKLYKLL 541
Score = 40.8 bits (94), Expect = 0.006
Identities = 83/417 (19%), Positives = 153/417 (36%), Gaps = 41/417 (9%)
Query: 484 GEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSALSSSRPTKKEEDRPPLR 543
G +P ES+ E+G L +E + V + +T+ L+ S+ K+++
Sbjct: 714 GYLPKKESKTGDESGALPVPQESIMENVDQAITKKDQ---SQVLTQSKEEKEKQ------ 764
Query: 544 GFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMATILH----LGKSS 599
LL FV +T+ L V K ++ S V EA T H SS
Sbjct: 765 --LLASSLFVGLGSESTIN--LLGKADTVSHKFRRKSKVKEAKSGETTSTHNMTCSSFSS 820
Query: 600 LPKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESE 659
L DD S ++D +KE ++ + S L+ E L++ E
Sbjct: 821 LSNVAYEDDYY-------------SNTLHDTGDKELKKF--SLTSELLDSESLTELPLVE 865
Query: 660 KRNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKVTQL 719
K + +S L A N M + A ++ + ++
Sbjct: 866 KFSYC-----SLSTPSLFANNNMEIFHPPQSTAASVAKESSLASSFLEETTEYIHSNAME 920
Query: 720 TGFSDPVYAEAYVHVNQYDIVLDVLVVNQTSDTLQNCTLELATLGDLKLVEKPSPLTLAP 779
++ + +Y +++ V N++ L++ LE+ + K+ E+P L
Sbjct: 921 VCNNETISVSSYKIWKDDCLLMVWSVTNKSGLELKSADLEIFPAENFKVTEQPG-CCLPV 979
Query: 780 HDFANIKANVKVASTENGIIFGNIVYDVSGAASDRNCVVLS-DIHIDIMDYIQPATCTDA 838
+ + K+ E GN+ +S D + L +++ ++D+I+P +
Sbjct: 980 MEAESTKSFQYSVQIEKPFTEGNLTGFISYHMMDTHSAQLEFSVNLSLLDFIRPLKISSD 1039
Query: 839 EFRQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCLTPEKALSGYCGFMAANL 895
+F ++W F N V N M + L LK+ K + G G +A L
Sbjct: 1040 DFGKLWLSF--ANDVKQNVKMSESQAALPSALKTLQQKLRLHIIEIIGNEGLLACQL 1094
>gi|71773010 adaptor-related protein complex 1, gamma 1 subunit
isoform a [Homo sapiens]
Length = 825
Score = 55.1 bits (131), Expect = 3e-07
Identities = 87/477 (18%), Positives = 191/477 (40%), Gaps = 76/477 (15%)
Query: 99 ILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLA 158
+L+ + + DL H +F++G L L + +E+ L + L+ +SY+R+ A L
Sbjct: 101 LLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALC 160
Query: 159 IYTIYRNFEHLIPDAPELIHDF------LVNEKD------------ASCKRNAFMMLIHA 200
H+I PEL+ F L+NEK+ C+R+ M+
Sbjct: 161 AV-------HVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFR 213
Query: 201 DQDRALDYLSTCIDQVQTFG------------DILQLVIVELIYKVCHANPSERARFIRC 248
++ + L + + G LQ+ I+ L+ ++ N + + +
Sbjct: 214 KNEKLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLL-RILGRNDDDSSEAMND 272
Query: 249 IYNLLQSSSP-------AVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIV 301
I + +++ A+ YE T++ + S + ++ A + + +D N++ +
Sbjct: 273 ILAQVATNTETSKNVGNAILYETVLTIMDIKS-ESGLRVLAINILGRFLLNNDKNIRYVA 331
Query: 302 LDRLIEL--KEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIV 359
L L++ +H A +R + ++D L+ L D+ ++++ ++L+ LV+ N+ ++
Sbjct: 332 LTSLLKTVQTDHNAVQR-HRSTIVDCLKDL---DVSIKRRAMELSFALVNGNNIRGMM-- 385
Query: 360 LKKEVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAAD 419
KE++ + E E ++ + + ++ I +M L+ D
Sbjct: 386 --KELLYFLDSCEPE----FKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDD 439
Query: 420 VLEFVREAIQRFDNLRMLIVEKMLE-VFHAIKSVKIYRGALWILGEY--------CSTKE 470
+ + + I + V+++ + + + + A W +GEY C +E
Sbjct: 440 AVPNLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEE 499
Query: 471 DIQSVMTEIRRSLGEIPIVESEIKKEAG-------ELKPEEEITVGPVQKLVTEMGT 520
IQ E+ L + I G +L TV ++K+V+ G+
Sbjct: 500 PIQVTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGS 556
>gi|71772942 adaptor-related protein complex 1, gamma 1 subunit
isoform b [Homo sapiens]
Length = 822
Score = 53.9 bits (128), Expect = 7e-07
Identities = 88/474 (18%), Positives = 191/474 (40%), Gaps = 73/474 (15%)
Query: 99 ILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLA 158
+L+ + + DL H +F++G L L + +E+ L + L+ +SY+R+ A L
Sbjct: 101 LLMTNCIKNDLNHSTQFVQGLALCTLGCMGSSEMCRDLAGEVEKLLKTSNSYLRKKAALC 160
Query: 159 IYTIYRNFEHLIPDAPELIHDF------LVNEKD------------ASCKRNAFMM---- 196
H+I PEL+ F L+NEK+ C+R+ M+
Sbjct: 161 AV-------HVIRKVPELMEMFLPATKNLLNEKNHGVLHTSVVLLTEMCERSPDMLAHFR 213
Query: 197 -----LIHADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIYN 251
L+ ++ + S D LQ+ I+ L+ ++ N + + + I
Sbjct: 214 KLVPQLVRILKNLIMSGYSPEHDVSGISDPFLQVRILRLL-RILGRNDDDSSEAMNDILA 272
Query: 252 LLQSSSP-------AVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDR 304
+ +++ A+ YE T++ + S + ++ A + + +D N++ + L
Sbjct: 273 QVATNTETSKNVGNAILYETVLTIMDIKS-ESGLRVLAINILGRFLLNNDKNIRYVALTS 331
Query: 305 LIEL--KEHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKK 362
L++ +H A +R + ++D L+ L D+ ++++ ++L+ LV+ N+ ++ K
Sbjct: 332 LLKTVQTDHNAVQR-HRSTIVDCLKDL---DVSIKRRAMELSFALVNGNNIRGMM----K 383
Query: 363 EVIKTNNVSEHEDTDKYRQLLVRTLHSCSVRFPDMAANVIPVLMEFLSDNNEAAAADVLE 422
E++ + E E ++ + + ++ I +M L+ D +
Sbjct: 384 ELLYFLDSCEPE----FKADCASGIFLAAEKYAPSKRWHIDTIMRVLTTAGSYVRDDAVP 439
Query: 423 FVREAIQRFDNLRMLIVEKMLE-VFHAIKSVKIYRGALWILGEY--------CSTKEDIQ 473
+ + I + V+++ + + + + A W +GEY C +E IQ
Sbjct: 440 NLIQLITNSVEMHAYTVQRLYKAILGDYSQQPLVQVAAWCIGEYGDLLVSGQCEEEEPIQ 499
Query: 474 SVMTEIRRSLGEIPIVESEIKKEAG-------ELKPEEEITVGPVQKLVTEMGT 520
E+ L + I G +L TV ++K+V+ G+
Sbjct: 500 VTEDEVLDILESVLISNMSTSVTRGYALTAIMKLSTRFTCTVNRIKKVVSIYGS 553
>gi|4503843 adaptor-related protein complex 1, gamma 2 subunit [Homo
sapiens]
Length = 785
Score = 50.1 bits (118), Expect = 1e-05
Identities = 61/288 (21%), Positives = 118/288 (40%), Gaps = 35/288 (12%)
Query: 99 ILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVLA 158
+L+ ++ + DL + ++G L L + AE+ L P + L YVR+ A+L
Sbjct: 102 LLITNSIKNDLSQGIQPVQGLALCTLSTMGSAEMCRDLAPEVEKLLLQPSPYVRKKAILT 161
Query: 159 IYTIYRNFEHL----IPDAPELIHD--------------FLVNEKDASCK--RNAFMMLI 198
+ R L +P +L+H+ L A+ + R L+
Sbjct: 162 AVHMIRKVPELSSVFLPPCAQLLHERHHGILLGTITLITELCERSPAALRHFRKVVPQLV 221
Query: 199 HADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSERARFIRCIY-------N 251
H + ST LQ+ I+ L+ ++ N E + + + +
Sbjct: 222 HILRTLVTMGYSTEHSISGVSDPFLQVQILRLL-RILGRNHEESSETMNDLLAQVATNTD 280
Query: 252 LLQSSSPAVKYEAAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLIEL--K 309
+++ AV +E T++ + SA ++ A + + SD N++ + L L+ L
Sbjct: 281 TSRNAGNAVLFETVLTIMDIRSA-AGLRVLAVNILGRFLLNSDRNIRYVALTSLLRLVQS 339
Query: 310 EHPAHERVLQDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELV 357
+H A +R +V L D + ++ L+L+L LV+S NV ++
Sbjct: 340 DHSAVQRHRPTVV----ECLRETDASLSRRALELSLALVNSSNVRAMM 383
>gi|166197671 adaptor-related protein complex 4, beta 1 subunit
[Homo sapiens]
Length = 739
Score = 43.9 bits (102), Expect = 7e-04
Identities = 34/116 (29%), Positives = 54/116 (46%), Gaps = 6/116 (5%)
Query: 42 LKKVIIMILNGEKLPGLLMTIIRFVLPLQDHTIKKLLLVFWEIVPKTTPDGRLLHEMILV 101
+++VI + G + G+ M +++ + D KKL+ ++ PD LL
Sbjct: 33 IQRVIRYMTQGLDMSGVFMEMVKASATV-DIVQKKLVYLYMCTYAPLKPDLALL-----A 86
Query: 102 CDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAVL 157
+ KD PN +RG LR +C L+ + E + I L + SYVRR AVL
Sbjct: 87 INTLCKDCSDPNPMVRGLALRSMCSLRMPGVQEYIQQPILNGLRDKASYVRRVAVL 142
>gi|109134349 coatomer protein complex, subunit gamma 2 [Homo
sapiens]
Length = 871
Score = 37.4 bits (85), Expect = 0.067
Identities = 52/274 (18%), Positives = 117/274 (42%), Gaps = 59/274 (21%)
Query: 97 EMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRRNAV 156
++I+V + KD+ + RG +R LC++ + +L+ + ++ + + S V +A+
Sbjct: 101 DVIIVTSSLTKDMTGKEDVYRGPAIRALCRITDGTMLQAIERYMKQAIVDKVSSVSSSAL 160
Query: 157 LA----IYTIYRNFEHLIPDAPE---------------LIHDFLVNEKDASCK------- 190
++ + Y + I +A E +++ N++ A K
Sbjct: 161 VSSLHMMKISYDVVKRWINEAQEAASSDNIMVQYHALGVLYHLRKNDRLAVSKMLNKFTK 220
Query: 191 -----RNAFMMLIH-----------ADQDRALDYLSTCIDQVQTFGDILQLVIVELIYKV 234
+ A+ MLI + D++ +C+ ++VI E +
Sbjct: 221 SGLKSQFAYCMLIRIASRLLKETEDGHESPLFDFIESCLRNKH------EMVIYEAASAI 274
Query: 235 CHANPSERARFIRCIYNLLQ----SSSPAVKYEAAGTLVTLS-SAPTAIKAAAQCYIDL- 288
H P+ AR + ++LQ S PA++Y A TL ++ P+A+ A C +DL
Sbjct: 275 IHL-PNCTARELAPAVSVLQLFCSSPKPALRYAAVRTLNKVAMKHPSAVTA---CNLDLE 330
Query: 289 -IIKESDNNVKLIVLDRLIELKEHPAHERVLQDL 321
+I +S+ ++ + + L++ + +R+++ +
Sbjct: 331 NLITDSNRSIATLAITTLLKTGSESSVDRLMKQI 364
>gi|11559929 coatomer protein complex, subunit gamma 1 [Homo
sapiens]
Length = 874
Score = 36.2 bits (82), Expect = 0.15
Identities = 62/331 (18%), Positives = 137/331 (41%), Gaps = 42/331 (12%)
Query: 94 LLHEMILVCDAYRKDLQHPNEFIRGSTLRFLCKLKEAELLEPLMPAIRACLEHRHSYVRR 153
+ ++I+V + KD+ + RG +R LC++ ++ +L+ + ++ + + V
Sbjct: 98 IAEDVIIVTSSLTKDMTGKEDNYRGPAVRALCQITDSTMLQAIERYMKQAIVDKVPSVSS 157
Query: 154 NAVLAIYTIYRNFEHLIPDAPELIHDFLVNEKDASCKRNAFMMLIHA--------DQDR- 204
+A+++ HL+ + +++ + VNE + + M+ HA DR
Sbjct: 158 SALVSSL-------HLLKCSFDVVKRW-VNEAQEAASSDNIMVQYHALGLLYHVRKNDRL 209
Query: 205 ALDYLSTCIDQVQTFGDILQLVIVELIYKVCHANPSER-ARFIRCIYNLLQSSSPAVKYE 263
A++ + + + + +++ + K R + I + L++ V YE
Sbjct: 210 AVNKMISKVTRHGLKSPFAYCMMIRVASKQLEEEDGSRDSPLFDFIESCLRNKHEMVVYE 269
Query: 264 AAGTLVTLSSAPTAIKAAAQCYIDLIIKESDNNVKLIVLDRLIEL-KEHP----AHERVL 318
AA +V L A A + L ++ + L ++ +HP A L
Sbjct: 270 AASAIVNLPGCSAKELAPAVSVLQLFCSSPKAALRYAAVRTLNKVAMKHPSAVTACNLDL 329
Query: 319 QDLVMDILRVLSTPDLEVRKKTLQLALDLVSSRNVEELVIVLKKEVIKTNNVSEHEDTDK 378
++LV D R ++T LA+ + E + L K++ + E +D+
Sbjct: 330 ENLVTDSNRSIAT-----------LAITTLLKTGSESSIDRLMKQISSFMS----EISDE 374
Query: 379 YRQLLVRTLHSCSVRFPDMAANVIPVLMEFL 409
++ ++V+ + + ++P A VLM FL
Sbjct: 375 FKVVVVQAISALCQKYPRKHA----VLMNFL 401
>gi|151301127 dynein, axonemal, heavy chain 7 [Homo sapiens]
Length = 4024
Score = 34.7 bits (78), Expect = 0.44
Identities = 30/120 (25%), Positives = 55/120 (45%), Gaps = 8/120 (6%)
Query: 771 KPSPLTLAPHDFA-NIKANVKVASTENGIIFGNIVYDVS---GAASDRNCVVLSDIHIDI 826
K PLT AP F N A++ +E ++F NI+ S GA + + V++++ DI
Sbjct: 3697 KTLPLTPAPEIFGMNANADITKDQSETQLLFDNILLTQSRSAGAGAKSSDEVVNEVASDI 3756
Query: 827 MDYIQPATCTDAEFRQMWAEFEWENKVTVNTNMVDLNDYLQHILKSTNMKCLTPEKALSG 886
+ + +A R+ + ++NT +V +LK+ C+ +KA+ G
Sbjct: 3757 LGKLPNNFDIEAAMRRYPTTYTQ----SMNTVLVQEMGRFNKLLKTIRDSCVNIQKAIKG 3812
>gi|51093836 hypothetical protein LOC126859 isoform 1 [Homo sapiens]
Length = 1012
Score = 34.3 bits (77), Expect = 0.57
Identities = 35/172 (20%), Positives = 79/172 (45%), Gaps = 21/172 (12%)
Query: 561 LTKIALRYVALVQEKKKQNSFVAEAMLLMATILHLGKSSLPKKPITDD--DVDRISL-CL 617
+ ++ L + L ++ + +S+++ M T + L KS+ K T+D +VD++ C
Sbjct: 741 VARLELDAIELTRKLYQYSSYLSSCCKGMVTAMALSKSTNSHKNATEDLYEVDKLKKECY 800
Query: 618 KVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEKRNVTVQPDDPISFMQLT 677
+ ++ CS L+++I ++ + LEEE + + ++P+ SF +
Sbjct: 801 EWINTCSCLLSNIKGRKITLLTYEEIERLLEEEAVKE---------FIEPEIDESFKE-- 849
Query: 678 AKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKVTQLTGFSDPVYAE 729
+E KED+ N +R E +++ K+ + G + V+++
Sbjct: 850 --DEEESKEDR-----KLQEENKERAEEQPSTSTEKEKLIRFIGEDENVHSK 894
>gi|95147555 microtubule-associated protein 1A [Homo sapiens]
Length = 2803
Score = 33.9 bits (76), Expect = 0.74
Identities = 39/175 (22%), Positives = 74/175 (42%), Gaps = 9/175 (5%)
Query: 522 ATQSALSSSR-PTKKEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNS 580
ATQ L+S PT + + R D + A+ T ++K+A R + + K+ S
Sbjct: 294 ATQKDLASGAVPTNLKPSKIKQRA---DSKESLKATTKTAVSKLAKREEVVEEGAKEARS 350
Query: 581 FVAEAMLLMATILHLGKSSLPKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLS 640
+A+ + P+KP + V S + + + + K ++ +S
Sbjct: 351 ELAKELAKTEKKAKESSEKPPEKPAKPERVKTESSEALKAEKRKLIKDKVGKKHLKEKIS 410
Query: 641 HMLSAKLEEEKLSQKKESEKRNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSLLA 695
KLEE+K +KKE +K ++ D+ + AK E K+ + +L ++
Sbjct: 411 -----KLEEKKDKEKKEIKKERKELKKDEGRKEEKKDAKKEEKRKDTKPELKKIS 460
>gi|64085252 hypothetical protein LOC145508 [Homo sapiens]
Length = 1094
Score = 33.9 bits (76), Expect = 0.74
Identities = 38/194 (19%), Positives = 75/194 (38%), Gaps = 11/194 (5%)
Query: 472 IQSVMTEIRRSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSALSSSR 531
++ + + ++ E+ ++I KE ELK + + ++ L E+ T+ AL
Sbjct: 500 LERALEKQSETVDELTGKNNQILKEKDELKTQLYAALQQIENLRKELNDVLTKRALQEEE 559
Query: 532 PTKKEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSFVAEAMLLMAT 591
KEE ++ D + V SL T L E KKQ+ ++ + A
Sbjct: 560 LHSKEEKLRDIKSHQADLELEVKNSLDT--------IHRLESELKKQSKIQSQMKVEKA- 610
Query: 592 ILHLGKSSLPKKPITDDDVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEK 651
HL + K D ++ + + + S + D+ NK + + K +
Sbjct: 611 --HLEEEIAELKKSQAQDKAKLLEMQESIKDLSAIRADLANKLAEEERAKKAVLKDLSDL 668
Query: 652 LSQKKESEKRNVTV 665
+Q K ++ T+
Sbjct: 669 TAQAKSRDEETATI 682
>gi|239744625 PREDICTED: hypothetical protein XP_002343208 [Homo
sapiens]
Length = 333
Score = 33.5 bits (75), Expect = 0.97
Identities = 17/68 (25%), Positives = 33/68 (48%)
Query: 754 QNCTLELATLGDLKLVEKPSPLTLAPHDFANIKANVKVASTENGIIFGNIVYDVSGAASD 813
+NCT L G +VE+ L DF +++ N+ V E ++ G+++ SGA +
Sbjct: 242 KNCTSHLVDEGGKLVVEELDLFALFRPDFLDLRVNLHVEGGEQALVDGDLLNSPSGADGE 301
Query: 814 RNCVVLSD 821
+ ++
Sbjct: 302 ARATLTTE 309
>gi|127138957 zinc finger protein 537 [Homo sapiens]
Length = 1081
Score = 33.5 bits (75), Expect = 0.97
Identities = 31/145 (21%), Positives = 56/145 (38%), Gaps = 9/145 (6%)
Query: 469 KEDIQSVMTEIRRSLGEIPIVESEIKKEAGELKPEEEITVGPVQKLVTEMGTYATQSALS 528
K + ++ +++ ++ VE ++K+ G+L P + T P +E+G A S
Sbjct: 604 KTNFHAMEELVKKVTEKVAKVEEKMKEPDGKLSPPKRATPSPCS---SEVGEPIKMEASS 660
Query: 529 SSRPTKKEEDRPPLRGFLLDGDFFV-----AASLATTLTKIALRYVALVQEKKKQNSFVA 583
+E P R DG L L A++ + + FV
Sbjct: 661 DGGFRSQENSPSPPRDGCKDGSPLAEPVENGKELVKPLASSLSGSTAIITDHPPEQPFVN 720
Query: 584 EAMLLMATI-LHLGKSSLPKKPITD 607
L + + +HLGK++ P P D
Sbjct: 721 PLSALQSVMNIHLGKAAKPSLPALD 745
>gi|109659847 filamin A interacting protein 1-like isoform 3 [Homo
sapiens]
Length = 1133
Score = 33.1 bits (74), Expect = 1.3
Identities = 27/109 (24%), Positives = 54/109 (49%), Gaps = 7/109 (6%)
Query: 609 DVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEK-RNVTVQP 667
+V+++S + L + + D FNK ++ S L LE+E+++ K+ S++ ++ V+
Sbjct: 416 EVEKLSKRIMALEK----LEDAFNKSKQECYS--LKCNLEKERMTTKQLSQELESLKVRI 469
Query: 668 DDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKV 716
+ + K E KED +L L M +RK ++ L +K+
Sbjct: 470 KELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKL 518
>gi|109659849 filamin A interacting protein 1-like isoform 2 [Homo
sapiens]
Length = 893
Score = 33.1 bits (74), Expect = 1.3
Identities = 27/109 (24%), Positives = 54/109 (49%), Gaps = 7/109 (6%)
Query: 609 DVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEK-RNVTVQP 667
+V+++S + L + + D FNK ++ S L LE+E+++ K+ S++ ++ V+
Sbjct: 176 EVEKLSKRIMALEK----LEDAFNKSKQECYS--LKCNLEKERMTTKQLSQELESLKVRI 229
Query: 668 DDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKV 716
+ + K E KED +L L M +RK ++ L +K+
Sbjct: 230 KELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKL 278
>gi|109659845 filamin A interacting protein 1-like isoform 1 [Homo
sapiens]
Length = 1135
Score = 33.1 bits (74), Expect = 1.3
Identities = 27/109 (24%), Positives = 54/109 (49%), Gaps = 7/109 (6%)
Query: 609 DVDRISLCLKVLSECSPLMNDIFNKECRQSLSHMLSAKLEEEKLSQKKESEK-RNVTVQP 667
+V+++S + L + + D FNK ++ S L LE+E+++ K+ S++ ++ V+
Sbjct: 416 EVEKLSKRIMALEK----LEDAFNKSKQECYS--LKCNLEKERMTTKQLSQELESLKVRI 469
Query: 668 DDPISFMQLTAKNEMNCKEDQFQLSLLAAMGNTQRKEAADPLASKLNKV 716
+ + K E KED +L L M +RK ++ L +K+
Sbjct: 470 KELEAIESRLEKTEFTLKEDLTKLKTLTVMFVDERKTMSEKLKKTEDKL 518
>gi|71061468 centromere protein E [Homo sapiens]
Length = 2701
Score = 33.1 bits (74), Expect = 1.3
Identities = 51/268 (19%), Positives = 118/268 (44%), Gaps = 29/268 (10%)
Query: 471 DIQSVMTEIRRSLGEIPIVESEIKKEAGELKPEEEITVGPVQKL---VTEMGTYATQSAL 527
++Q M+E+++ + EI +++E+K + L+ E + QKL E+ + + +
Sbjct: 1145 NVQEEMSEMQKKINEIENLKNELKNKELTLEHMETERLELAQKLNENYEEVKSITKERKV 1204
Query: 528 SSSRPTKKEEDRPPLRGFLLDGDFFVAASLATTLTKIALRYVALVQEKKKQNSF---VAE 584
E +R LRG++ + + A+ T ++ + ++ L + ++ + V+E
Sbjct: 1205 LKELQKSFETERDHLRGYIRE----IEATGLQTKEELKIAHIHLKEHQETIDELRRSVSE 1260
Query: 585 AMLLMATILHLGKSSLPKK---PITDDDVDRISLCLKVLSECSPLMNDI-FNKECRQSLS 640
+ L KS + P+ ++ + + +K +SE MN++ E +
Sbjct: 1261 KTAQIINTQDLEKSHTKLQEEIPVLHEEQELLP-NVKEVSETQETMNELELLTEQSTTKD 1319
Query: 641 HMLSAKLEEEKLS-----QKKESEKRNVTVQPDDPISFMQLTAKNEMNCKEDQFQLSLLA 695
A++E E+L Q+ + E +++T + D+ T K + K DQ + +
Sbjct: 1320 STTLARIEMERLRLNEKFQESQEEIKSLTKERDN-----LKTIKEALEVKHDQLKEHIRE 1374
Query: 696 AMGNTQ----RKEAADPLASKLNKVTQL 719
+ Q ++E + + K N+ T++
Sbjct: 1375 TLAKIQESQSKQEQSLNMKEKDNETTKI 1402
>gi|19923599 calmin [Homo sapiens]
Length = 1002
Score = 33.1 bits (74), Expect = 1.3
Identities = 57/208 (27%), Positives = 94/208 (45%), Gaps = 20/208 (9%)
Query: 471 DIQSVMTEIRRSLGEIPIVESEIKKEAGELKPEE----EITVGPVQK-----LVTEMG-- 519
D QS+MT + + L P +E+E ++ + P E I P ++ ++TE G
Sbjct: 275 DEQSIMTYVAQFLERFPELEAEDIFDSDKEVPIESTFVRIKETPSEQESKVFVLTENGER 334
Query: 520 TYATQSALSSSRPTKKEE-DRP-PLRGFLLDGDFFVAASLATT--LTKIALRYVALVQEK 575
TY S P+K D+P ++ F LDG A S ++T + +I + + K
Sbjct: 335 TYTVNHETSHPPPSKVFVCDKPESMKEFRLDGVSSHALSDSSTEFMHQIIDQVLQGGPGK 394
Query: 576 KKQNSFVAEAMLLMATILHLGKS-SLPKKPITDDDVD--RISLCLKVLSECSPLMNDIFN 632
S + ++++ G+S SLP K + D + C K LS C +
Sbjct: 395 TSDISEPSPESSILSSRKENGRSNSLPIKKTVHFEADTYKDPFCSKNLSLCFEGSPRVAK 454
Query: 633 KECRQSLSHMLSAKLEEEKLSQKKESEK 660
+ RQ H+L+ ++ EEK QK+ES K
Sbjct: 455 ESLRQD-GHVLAVEVAEEK-EQKQESSK 480
>gi|197304715 vav 2 guanine nucleotide exchange factor isoform 1
[Homo sapiens]
Length = 878
Score = 32.7 bits (73), Expect = 1.7
Identities = 35/143 (24%), Positives = 65/143 (45%), Gaps = 5/143 (3%)
Query: 396 DMAANVIPVLMEFLSDNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIY 455
D+ N + L LS + AA LE + + F LR + V M+ K +
Sbjct: 219 DIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHSF--LRAIDVSVMVGGSTLAKVFLDF 276
Query: 456 RGALWILGEYCSTKEDIQSVMTEIRRSLGEI--PIVESEIKKEAGELKPEEEITVGPVQK 513
+ L I GEYCS E Q+ + ++ S + + E +K + G+ K ++ + V P+Q+
Sbjct: 277 KERLLIYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLVV-PMQR 335
Query: 514 LVTEMGTYATQSALSSSRPTKKE 536
++ + S+ RP +++
Sbjct: 336 VLKYHLLLKELLSHSAERPERQQ 358
>gi|40549448 vav 2 guanine nucleotide exchange factor isoform 2
[Homo sapiens]
Length = 839
Score = 32.7 bits (73), Expect = 1.7
Identities = 35/143 (24%), Positives = 65/143 (45%), Gaps = 5/143 (3%)
Query: 396 DMAANVIPVLMEFLSDNNEAAAADVLEFVREAIQRFDNLRMLIVEKMLEVFHAIKSVKIY 455
D+ N + L LS + AA LE + + F LR + V M+ K +
Sbjct: 214 DIEKNYMSPLRLVLSPADMAAVFINLEDLIKVHHSF--LRAIDVSVMVGGSTLAKVFLDF 271
Query: 456 RGALWILGEYCSTKEDIQSVMTEIRRSLGEI--PIVESEIKKEAGELKPEEEITVGPVQK 513
+ L I GEYCS E Q+ + ++ S + + E +K + G+ K ++ + V P+Q+
Sbjct: 272 KERLLIYGEYCSHMEHAQNTLNQLLASREDFRQKVEECTLKVQDGKFKLQDLLVV-PMQR 330
Query: 514 LVTEMGTYATQSALSSSRPTKKE 536
++ + S+ RP +++
Sbjct: 331 VLKYHLLLKELLSHSAERPERQQ 353
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.134 0.378
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 32,836,657
Number of Sequences: 37866
Number of extensions: 1380776
Number of successful extensions: 4113
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 18
Number of HSP's successfully gapped in prelim test: 33
Number of HSP's that attempted gapping in prelim test: 4047
Number of HSP's gapped (non-prelim): 83
length of query: 953
length of database: 18,247,518
effective HSP length: 112
effective length of query: 841
effective length of database: 14,006,526
effective search space: 11779488366
effective search space used: 11779488366
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.8 bits)
S2: 67 (30.4 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.