BLASTP 2.2.11 [Jun-05-2005] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), "Gapped BLAST and PSI-BLAST: a new generation of protein database search programs", Nucleic Acids Res. 25:3389-3402. Query= gi|221218991 neuroblastoma breakpoint family, member 4 [Homo sapiens] (638 letters) Database: hs.faa 37,866 sequences; 18,247,518 total letters Searching..................................................done Score E Sequences producing significant alignments: (bits) Value gi|221218991 neuroblastoma breakpoint family, member 4 [Homo sap... 1286 0.0 gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2... 1277 0.0 gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1... 1262 0.0 gi|157266285 hypothetical protein LOC728936 [Homo sapiens] 479 e-135 gi|156071420 hypothetical protein LOC728912 [Homo sapiens] 477 e-134 gi|119709825 neuroblastoma breakpoint family, member 11-like [Ho... 477 e-134 gi|29789405 hypothetical protein LOC284565 [Homo sapiens] 476 e-134 gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo ... 474 e-133 gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo sap... 474 e-133 gi|92110019 hypothetical protein LOC55672 [Homo sapiens] 472 e-133 gi|83415174 hypothetical protein LOC400818 [Homo sapiens] 470 e-132 gi|224589132 hypothetical protein LOC100132406 [Homo sapiens] 468 e-131 gi|14149997 neuroblastoma breakpoint family, member 3 [Homo sapi... 459 e-129 gi|114158664 hypothetical protein LOC343505 [Homo sapiens] 416 e-116 gi|7657017 hypothetical protein LOC25832 [Homo sapiens] 395 e-110 gi|239741297 PREDICTED: neuroblastoma breakpoint family, member ... 368 e-102 gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint fami... 145 1e-34 gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint fami... 142 9e-34 gi|239741281 PREDICTED: Neuroblastoma breakpoint family member 6... 142 9e-34 gi|239752894 PREDICTED: Neuroblastoma breakpoint family member 6... 138 1e-32 gi|157311604 phosphodiesterase 4D interacting protein isoform 1 ... 97 6e-20 gi|239758011 PREDICTED: hypothetical protein LOC728841, partial ... 80 6e-15 gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sa... 59 1e-08 gi|150010604 kinesin family member 4B [Homo sapiens] 52 2e-06 gi|239745079 PREDICTED: Putative golgin subfamily A member 6-lik... 51 3e-06 gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-li... 49 1e-05 gi|116686122 kinesin family member 4 [Homo sapiens] 49 1e-05 gi|148839339 nexilin (F actin binding protein) [Homo sapiens] 49 1e-05 gi|100816397 MYST histone acetyltransferase (monocytic leukemia)... 48 2e-05 gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sa... 48 3e-05 >gi|221218991 neuroblastoma breakpoint family, member 4 [Homo sapiens] Length = 638 Score = 1286 bits (3329), Expect = 0.0 Identities = 638/638 (100%), Positives = 638/638 (100%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK Sbjct: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 Query: 61 CEEYKDIIDSVLRDELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDAS 120 CEEYKDIIDSVLRDELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDAS Sbjct: 61 CEEYKDIIDSVLRDELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDAS 120 Query: 121 RWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEE 180 RWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEE Sbjct: 121 RWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEE 180 Query: 181 VEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDS 240 VEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDS Sbjct: 181 VEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDS 240 Query: 241 ALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFLALDEQ 300 ALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFLALDEQ Sbjct: 241 ALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFLALDEQ 300 Query: 301 KVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQES 360 KVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQES Sbjct: 301 KVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQES 360 Query: 361 LDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEEIEDQSPPCPRLSQ 420 LDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEEIEDQSPPCPRLSQ Sbjct: 361 LDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEEIEDQSPPCPRLSQ 420 Query: 421 ELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDVASPTEAA 480 ELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDVASPTEAA Sbjct: 421 ELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDVASPTEAA 480 Query: 481 CPQGTWSGDLSHHQSEVQVSQAQLEPSTLVPSCLRLQLDQGFHCGNGLAQRGLSSTTCSF 540 CPQGTWSGDLSHHQSEVQVSQAQLEPSTLVPSCLRLQLDQGFHCGNGLAQRGLSSTTCSF Sbjct: 481 CPQGTWSGDLSHHQSEVQVSQAQLEPSTLVPSCLRLQLDQGFHCGNGLAQRGLSSTTCSF 540 Query: 541 SANADSGNQWPFQELVLEPSLGMKNPPQLEDDALEGSASNTQGRQVTGRIRASLVLILKT 600 SANADSGNQWPFQELVLEPSLGMKNPPQLEDDALEGSASNTQGRQVTGRIRASLVLILKT Sbjct: 541 SANADSGNQWPFQELVLEPSLGMKNPPQLEDDALEGSASNTQGRQVTGRIRASLVLILKT 600 Query: 601 IRRRLPFSKWRLAFRFAGPHAESAEIPNTAGRTQRMAG 638 IRRRLPFSKWRLAFRFAGPHAESAEIPNTAGRTQRMAG Sbjct: 601 IRRRLPFSKWRLAFRFAGPHAESAEIPNTAGRTQRMAG 638 >gi|221136848 neuroblastoma breakpoint family, member 6 isoform 2 [Homo sapiens] Length = 638 Score = 1277 bits (3305), Expect = 0.0 Identities = 633/638 (99%), Positives = 635/638 (99%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK Sbjct: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 Query: 61 CEEYKDIIDSVLRDELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDAS 120 CEEYKDIIDSVLRDELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDAS Sbjct: 61 CEEYKDIIDSVLRDELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDAS 120 Query: 121 RWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEE 180 RWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEE Sbjct: 121 RWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEE 180 Query: 181 VEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDS 240 VEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDS Sbjct: 181 VEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDS 240 Query: 241 ALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFLALDEQ 300 ALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFLALDEQ Sbjct: 241 ALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFLALDEQ 300 Query: 301 KVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQES 360 KVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQES Sbjct: 301 KVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQES 360 Query: 361 LDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEEIEDQSPPCPRLSQ 420 LDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEEIEDQSPPCPRLSQ Sbjct: 361 LDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEEIEDQSPPCPRLSQ 420 Query: 421 ELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDVASPTEAA 480 ELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDVASPTEAA Sbjct: 421 ELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDVASPTEAA 480 Query: 481 CPQGTWSGDLSHHQSEVQVSQAQLEPSTLVPSCLRLQLDQGFHCGNGLAQRGLSSTTCSF 540 CPQGTWSGDLSHH+SEVQ+SQAQLEPSTLVPSCLRLQLDQGFHCGNGLAQRGLSSTTCSF Sbjct: 481 CPQGTWSGDLSHHRSEVQISQAQLEPSTLVPSCLRLQLDQGFHCGNGLAQRGLSSTTCSF 540 Query: 541 SANADSGNQWPFQELVLEPSLGMKNPPQLEDDALEGSASNTQGRQVTGRIRASLVLILKT 600 SANADSGNQWPFQELVLEPSLGMKNPPQLEDDALEGSASNTQGRQVTGRIRASLVLILKT Sbjct: 541 SANADSGNQWPFQELVLEPSLGMKNPPQLEDDALEGSASNTQGRQVTGRIRASLVLILKT 600 Query: 601 IRRRLPFSKWRLAFRFAGPHAESAEIPNTAGRTQRMAG 638 IRRRLPFSKWRLAFRFAGPHAESAEIPNTA R QRM G Sbjct: 601 IRRRLPFSKWRLAFRFAGPHAESAEIPNTAERMQRMIG 638 >gi|221136844 neuroblastoma breakpoint family, member 6 isoform 1 [Homo sapiens] Length = 667 Score = 1262 bits (3265), Expect = 0.0 Identities = 633/667 (94%), Positives = 635/667 (95%), Gaps = 29/667 (4%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK Sbjct: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 Query: 61 CEEYKDIIDSVLRDELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDAS 120 CEEYKDIIDSVLRDELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDAS Sbjct: 61 CEEYKDIIDSVLRDELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDAS 120 Query: 121 RWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEE 180 RWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEE Sbjct: 121 RWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEE 180 Query: 181 VEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDS 240 VEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDS Sbjct: 181 VEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDS 240 Query: 241 ALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR--------------------- 279 ALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR Sbjct: 241 ALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRNRQSLEPGELTNLRDFLISPV 300 Query: 280 --------HHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDL 331 HHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDL Sbjct: 301 VSHVANPGHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDL 360 Query: 332 EEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDK 391 EEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDK Sbjct: 361 EEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDK 420 Query: 392 QVSLALVDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451 QVSLALVDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC Sbjct: 421 QVSLALVDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 480 Query: 452 HQPYSSTLSSLEDQLACSALDVASPTEAACPQGTWSGDLSHHQSEVQVSQAQLEPSTLVP 511 HQPYSSTLSSLEDQLACSALDVASPTEAACPQGTWSGDLSHH+SEVQ+SQAQLEPSTLVP Sbjct: 481 HQPYSSTLSSLEDQLACSALDVASPTEAACPQGTWSGDLSHHRSEVQISQAQLEPSTLVP 540 Query: 512 SCLRLQLDQGFHCGNGLAQRGLSSTTCSFSANADSGNQWPFQELVLEPSLGMKNPPQLED 571 SCLRLQLDQGFHCGNGLAQRGLSSTTCSFSANADSGNQWPFQELVLEPSLGMKNPPQLED Sbjct: 541 SCLRLQLDQGFHCGNGLAQRGLSSTTCSFSANADSGNQWPFQELVLEPSLGMKNPPQLED 600 Query: 572 DALEGSASNTQGRQVTGRIRASLVLILKTIRRRLPFSKWRLAFRFAGPHAESAEIPNTAG 631 DALEGSASNTQGRQVTGRIRASLVLILKTIRRRLPFSKWRLAFRFAGPHAESAEIPNTA Sbjct: 601 DALEGSASNTQGRQVTGRIRASLVLILKTIRRRLPFSKWRLAFRFAGPHAESAEIPNTAE 660 Query: 632 RTQRMAG 638 R QRM G Sbjct: 661 RMQRMIG 667 >gi|157266285 hypothetical protein LOC728936 [Homo sapiens] Length = 670 Score = 479 bits (1232), Expect = e-135 Identities = 277/499 (55%), Positives = 343/499 (68%), Gaps = 47/499 (9%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA PLSSE+AEMNILEIN++LR QLAE QQFR+LKEK +TQ + LAN+ KKYK Sbjct: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59 Query: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 EE KD+I +LR+E Q EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDA Sbjct: 60 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 119 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RL +HLV KLSPEND D+DED + E Sbjct: 120 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDV--QVE 177 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 EKVQ+S APRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPH+ TKITF+E +VD Sbjct: 178 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVD 237 Query: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285 S L+ S H E E+A++I PEN++D EEEE K PV PR+ +S Sbjct: 238 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 295 Query: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 SY+ +F +L+EQ+VC A D+ R +WD+ K+ D Sbjct: 296 TLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED----- 340 Query: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395 QE PRLSR L + E+ Q+SLD C TPS +LT S PY S Y E ++V L Sbjct: 341 -QEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGL 399 Query: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454 A+ +D+I+K QE EDQ P CPRLS+EL + KE EV +DS++ Y TPS + ++ D QP Sbjct: 400 AIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQP 459 Query: 455 YSSTLSSLEDQLACSALDV 473 YSS + SLE+Q ALDV Sbjct: 460 YSSAVYSLEEQYLGLALDV 478 Score = 114 bits (285), Expect = 3e-25 Identities = 99/329 (30%), Positives = 150/329 (45%), Gaps = 49/329 (14%) Query: 178 DEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFK 234 D+ ++ QE+ PR E+ +E EV QDSL+ C T S ++S QP+RS + Sbjct: 334 DQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLE 393 Query: 235 EHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSF 294 + V A+ ++ E + E EE + P PR + + EV Sbjct: 394 QQRVGLAIDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 437 Query: 295 LALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKGQETVAPR 343 +LD D+ + YS+ + +E LG + D EE + Q PR Sbjct: 438 DSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPR 497 Query: 344 LSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL------ 397 LSR L V + E+ Q+SLD C TPS + S PY S+ Y+ E+K V +L Sbjct: 498 LSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIE 557 Query: 398 -------------VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSV 444 K ++ ++E ED +PPCPRL+ L EV+E EV +DS++ Y T S+ Sbjct: 558 KKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLNGVLMEVEEPEVLQDSLDRCYSTQSM 617 Query: 445 HHDVSDCHQPYSSTLSSLEDQLACSALDV 473 + ++ D Q Y S S E++ AL V Sbjct: 618 YFELPDSFQHYRSVFYSFEEEHISFALYV 646 Score = 36.6 bits (83), Expect = 0.073 Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Query: 188 PAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVV 244 P PR + + EE EV QDSL+ C T S +S Q +RS +F+E + AL V Sbjct: 587 PCPRLNGVLMEVEEPEVLQDSLDRCYSTQSMYFELPDSFQHYRSVFYSFEEEHISFALYV 646 Query: 245 ES 246 ++ Sbjct: 647 DN 648 >gi|156071420 hypothetical protein LOC728912 [Homo sapiens] Length = 790 Score = 477 bits (1227), Expect = e-134 Identities = 289/546 (52%), Positives = 355/546 (65%), Gaps = 53/546 (9%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA PLSSE+AEMNILEIN++L QLAE QQFR LKEK +TQ + LA Q KYK Sbjct: 197 MVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACF-LAKQQNKYK 255 Query: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 EE KD+I S+LR+E Q EKLAE+L+QAEELRQYK LVHSQ +ELTQLREKLREGRDA Sbjct: 256 YEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 315 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D+DED + E Sbjct: 316 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVE 373 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 EKVQ+S +PRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPHR TKITF+E +VD Sbjct: 374 VAEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVD 433 Query: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285 S L+ S H E E+A++I PEN++D EEEE K PV PR+ +S Sbjct: 434 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 491 Query: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 SY+ +F +L+EQ+VC A D+ R +WD+ K+ D Sbjct: 492 TLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED----- 536 Query: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395 QE PRLSR L + E+ Q+SLD C TPS+ LT S PY S Y E +++ L Sbjct: 537 -QEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGL 595 Query: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454 A+ +D+I+K QE EDQ P CPRLS+EL KE EV +DS++ Y TPS + ++ D QP Sbjct: 596 AVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 655 Query: 455 YSSTLSSLEDQLACSALDV---ASPTEAACPQGTWSGDLSHHQSEV---QVSQAQLEPST 508 Y S + SLE+Q ALDV E QG LS EV +V Q L+ Sbjct: 656 YRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQ 715 Query: 509 LVPSCL 514 L+P L Sbjct: 716 LLPVVL 721 Score = 256 bits (653), Expect = 6e-68 Identities = 174/427 (40%), Positives = 239/427 (55%), Gaps = 50/427 (11%) Query: 90 EELRQYKALVHSQAKELTQLREKLREGRDASRWLNKHLKTLLTPDDPDKSQGQDLREQLA 149 +E++QYK LVHSQ +ELTQLREKLREGRDASR LN+HL+ LLTPD+PDKSQGQDL+EQLA Sbjct: 15 QEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74 Query: 150 EGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEKVQESPAPREVQKTEEKEVPQDSLEEC 209 EG RLA+HLV KLSPENDEDEDED + EE EKV ES APREVQK EE +VP+DSLEEC Sbjct: 75 EGCRLAQHLVQKLSPENDEDEDEDV--QVEEDEKVLESSAPREVQKAEESKVPEDSLEEC 132 Query: 210 AVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVVESEHPHDEEEEALNIPP-------- 261 A+TCSNSH P +S QPH++ KITF+E +V+S+LVV+ E HD ++ALNI P Sbjct: 133 AITCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSA 192 Query: 262 ------ENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFLALDEQKVCS--AQDVARDYS 313 + E+ + + + ++ F +L E+ + A +A+ + Sbjct: 193 TNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQN 252 Query: 314 NPKWDE-----TSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHE-----IPQESLDG 363 K++E S+ E+Q E++ Q A L + + V E + ++ +G Sbjct: 253 KYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREG 312 Query: 364 CCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLA--------LVDKIKKDQEEIED----- 410 + S+ L P +D Q LA LV K+ + + +D Sbjct: 313 RDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQV 372 Query: 411 ------QSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLED 464 Q PR E+ + +E+EVPEDS+ E +T S H D +QP+ T + E+ Sbjct: 373 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 429 Query: 465 QLACSAL 471 S L Sbjct: 430 DKVDSTL 436 Score = 41.6 bits (96), Expect = 0.002 Identities = 30/126 (23%), Positives = 60/126 (47%), Gaps = 19/126 (15%) Query: 348 PLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEE 407 P + ++ ++ +GC L ++ L+P ED+ V ++++D++ Sbjct: 61 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------EDEDEDV------QVEEDEKV 107 Query: 408 IEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLA 467 +E +P +E+ + +E +VPEDS+ E +T S H D QP+ + + E+ Sbjct: 108 LESSAP------REVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKV 161 Query: 468 CSALDV 473 S+L V Sbjct: 162 NSSLVV 167 >gi|119709825 neuroblastoma breakpoint family, member 11-like [Homo sapiens] Length = 790 Score = 477 bits (1227), Expect = e-134 Identities = 289/546 (52%), Positives = 355/546 (65%), Gaps = 53/546 (9%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA PLSSE+AEMNILEIN++L QLAE QQFR LKEK +TQ + LA Q KYK Sbjct: 197 MVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACF-LAKQQNKYK 255 Query: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 EE KD+I S+LR+E Q EKLAE+L+QAEELRQYK LVHSQ +ELTQLREKLREGRDA Sbjct: 256 YEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 315 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D+DED + E Sbjct: 316 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVE 373 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 EKVQ+S +PRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPHR TKITF+E +VD Sbjct: 374 VAEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVD 433 Query: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285 S L+ S H E E+A++I PEN++D EEEE K PV PR+ +S Sbjct: 434 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 491 Query: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 SY+ +F +L+EQ+VC A D+ R +WD+ K+ D Sbjct: 492 TLSIPPERLASYQSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED----- 536 Query: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395 QE PRLSR L + E+ Q+SLD C TPS+ LT S PY S Y E +++ L Sbjct: 537 -QEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSVYLGLTDSCQPYRSAFYVLEQQRIGL 595 Query: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454 A+ +D+I+K QE EDQ P CPRLS+EL KE EV +DS++ Y TPS + ++ D QP Sbjct: 596 AVDMDEIEKYQEVEEDQDPSCPRLSRELLAEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 655 Query: 455 YSSTLSSLEDQLACSALDV---ASPTEAACPQGTWSGDLSHHQSEV---QVSQAQLEPST 508 Y S + SLE+Q ALDV E QG LS EV +V Q L+ Sbjct: 656 YRSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDVIQ 715 Query: 509 LVPSCL 514 L+P L Sbjct: 716 LLPVVL 721 Score = 257 bits (656), Expect = 3e-68 Identities = 175/427 (40%), Positives = 239/427 (55%), Gaps = 50/427 (11%) Query: 90 EELRQYKALVHSQAKELTQLREKLREGRDASRWLNKHLKTLLTPDDPDKSQGQDLREQLA 149 EE++QYK LVHSQ +ELTQLREKLREGRDASR LN+HL+ LLTPD+PDKSQGQDL+EQLA Sbjct: 15 EEIQQYKVLVHSQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQEQLA 74 Query: 150 EGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEKVQESPAPREVQKTEEKEVPQDSLEEC 209 EG RLA+HLV KLSPENDEDEDED + EE EKV ES APREVQK EE +VP+DSLEEC Sbjct: 75 EGCRLAQHLVQKLSPENDEDEDEDV--QVEEDEKVLESSAPREVQKAEESKVPEDSLEEC 132 Query: 210 AVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVVESEHPHDEEEEALNIPP-------- 261 A+TCSNSH P +S QPH++ KITF+E +V+S+LVV+ E HD ++ALNI P Sbjct: 133 AITCSNSHGPCDSIQPHKNIKITFEEDKVNSSLVVDRESSHDGCQDALNILPVPGPTSSA 192 Query: 262 ------ENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFLALDEQKVCS--AQDVARDYS 313 + E+ + + + ++ F +L E+ + A +A+ + Sbjct: 193 TNVSMVVSAGPLSSEKAEMNILEINEKLCPQLAEKKQQFRSLKEKCFVTQVACFLAKQQN 252 Query: 314 NPKWDE-----TSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHE-----IPQESLDG 363 K++E S+ E+Q E++ Q A L + + V E + ++ +G Sbjct: 253 KYKYEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREG 312 Query: 364 CCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLA--------LVDKIKKDQEEIED----- 410 + S+ L P +D Q LA LV K+ + + +D Sbjct: 313 RDASRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQV 372 Query: 411 ------QSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLED 464 Q PR E+ + +E+EVPEDS+ E +T S H D +QP+ T + E+ Sbjct: 373 EVAEKVQKSSSPR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEE 429 Query: 465 QLACSAL 471 S L Sbjct: 430 DKVDSTL 436 Score = 41.6 bits (96), Expect = 0.002 Identities = 30/126 (23%), Positives = 60/126 (47%), Gaps = 19/126 (15%) Query: 348 PLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEE 407 P + ++ ++ +GC L ++ L+P ED+ V ++++D++ Sbjct: 61 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------EDEDEDV------QVEEDEKV 107 Query: 408 IEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLA 467 +E +P +E+ + +E +VPEDS+ E +T S H D QP+ + + E+ Sbjct: 108 LESSAP------REVQKAEESKVPEDSLEECAITCSNSHGPCDSIQPHKNIKITFEEDKV 161 Query: 468 CSALDV 473 S+L V Sbjct: 162 NSSLVV 167 >gi|29789405 hypothetical protein LOC284565 [Homo sapiens] Length = 670 Score = 476 bits (1225), Expect = e-134 Identities = 289/547 (52%), Positives = 359/547 (65%), Gaps = 54/547 (9%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA PLSSE+AEMNILEIN++LR QLAE QQFR+LKEK +TQ + LAN+ KKYK Sbjct: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59 Query: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 EE KD+I +LR+E Q EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDA Sbjct: 60 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 119 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RL +HLV KLSPEND D+DED + E Sbjct: 120 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLTQHLVQKLSPENDNDDDEDV--QVE 177 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 EKVQ+S APRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPH+ TKITF+E +VD Sbjct: 178 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHKKTKITFEEDKVD 237 Query: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285 S L+ S H E E+A++I PEN++D EEEE K PV PR+ +S Sbjct: 238 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 295 Query: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 SY+ +F +L+EQ+VC A D+ R +WD+ K+ D Sbjct: 296 TLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED----- 340 Query: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395 QE PRLSR L + E+ Q+SLD C TPS +LT S PY S Y E ++V L Sbjct: 341 -QEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGL 399 Query: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454 A+ +D+I+K QE EDQ P CPRLS+EL + KE EV +DS++ Y TPS + ++ D QP Sbjct: 400 AIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSDYLELPDLGQP 459 Query: 455 YSSTLSSLEDQ---LACSALDVASPTEAACPQGTWSGDLSHHQSEV---QVSQAQLEPST 508 YSS + SLE+Q LA + + E QG LS EV +V Q L+ Sbjct: 460 YSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 519 Query: 509 LVP-SCL 514 P SCL Sbjct: 520 STPSSCL 526 Score = 115 bits (287), Expect = 2e-25 Identities = 100/329 (30%), Positives = 149/329 (45%), Gaps = 49/329 (14%) Query: 178 DEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFK 234 D+ ++ QE+ PR E+ +E EV QDSL+ C T S ++S QP+RS + Sbjct: 334 DQVKKEDQEATGPRLSRELLDEKEPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLE 393 Query: 235 EHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSF 294 + V A+ ++ E + E EE + P PR + + EV Sbjct: 394 QQRVGLAIDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQ 437 Query: 295 LALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKGQETVAPR 343 +LD D+ + YS+ + +E LG + D EE + Q PR Sbjct: 438 DSLDRCYSTPSDYLELPDLGQPYSSAVYSLEEQYLGLALAVDRIKKDQEEEEDQGPPCPR 497 Query: 344 LSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL------ 397 LSR L V + E+ Q+SLD C TPS + S PY S+ Y+ E+K V +L Sbjct: 498 LSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIE 557 Query: 398 -------------VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSV 444 K ++ ++E ED +PPCPRL L EV+E EV +DS++ Y TPS+ Sbjct: 558 KKGKGKKRRGRRSKKKRRRGRKEGEDDNPPCPRLYGVLMEVEEPEVLQDSLDRCYSTPSM 617 Query: 445 HHDVSDCHQPYSSTLSSLEDQLACSALDV 473 + + D Q Y S S E++ AL V Sbjct: 618 YFEQPDSFQHYRSVFYSFEEEHISFALYV 646 Score = 37.4 bits (85), Expect = 0.043 Identities = 23/62 (37%), Positives = 33/62 (53%), Gaps = 3/62 (4%) Query: 188 PAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVV 244 P PR + + EE EV QDSL+ C T S +S Q +RS +F+E + AL V Sbjct: 587 PCPRLYGVLMEVEEPEVLQDSLDRCYSTPSMYFEQPDSFQHYRSVFYSFEEEHISFALYV 646 Query: 245 ES 246 ++ Sbjct: 647 DN 648 >gi|239741309 PREDICTED: hypothetical protein XP_002344485 [Homo sapiens] Length = 4621 Score = 474 bits (1219), Expect = e-133 Identities = 276/499 (55%), Positives = 341/499 (68%), Gaps = 47/499 (9%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA PLSSE+AEMNILEIN++L QLAE QQFR+LKE+ +TQ + LANQ KKYK Sbjct: 272 MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQLAGF-LANQQKKYK 330 Query: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 EE KD+I S+LR+E Q EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDA Sbjct: 331 YEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 390 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D+DED + E Sbjct: 391 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVE 448 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 EKVQ+S APRE+QK EEKEVP+DS EECA+T SNSH P +SNQPHR TKITF+E +VD Sbjct: 449 LAEKVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKTKITFEEDKVD 508 Query: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285 S L+ S H E E+A++I PEN++D EEEE K PV PR+ +S Sbjct: 509 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 566 Query: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 SY+ +F +L+EQ+VC A D+ R +WD+ K+ D Sbjct: 567 TLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED----- 611 Query: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395 QE PRLSR L E+ Q+SLD C TPS +LT S PY S Y E +++ L Sbjct: 612 -QEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRIGL 670 Query: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454 A+ +D+I+K QE EDQ P CPRLS+EL + KE EV +DS++ Y TPS + ++ D QP Sbjct: 671 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 730 Query: 455 YSSTLSSLEDQLACSALDV 473 YSS + SLE+Q ALDV Sbjct: 731 YSSAVYSLEEQYLGLALDV 749 Score = 359 bits (921), Expect = 5e-99 Identities = 235/517 (45%), Positives = 302/517 (58%), Gaps = 52/517 (10%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA P SSE+AEMNILEIN++LR QLAE+ QQF +LKE+ +TQ + LANQ KKY Sbjct: 1 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFVTQLAGF-LANQQKKYN 59 Query: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 EE KD+I +LR+E Q EKLAE+L+QAEELRQYK LVHSQ +ELTQLREKLREGRDA Sbjct: 60 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 SR LN+HL+ LLT D+PDKSQGQDL+EQLAEG RLA+HLV KLSPENDEDEDED + E Sbjct: 120 SRSLNEHLQALLTLDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDV--QVE 177 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 E EKVQ+S APREVQKTEE +VP+DSLEECA+TCSNSH P +SNQPH++ KITF+E EV+ Sbjct: 178 EAEKVQKSSAPREVQKTEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVN 237 Query: 240 SALVVESEHPHDEEEEALNIPP---------------------ENQNDHEEEEGKAPVPP 278 S LVV+ E HDE ++ALNI P + + E + P Sbjct: 238 STLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLHP 297 Query: 279 RHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQE 338 + +K +R+ + + Q Y K S+ E+Q E++ Q Sbjct: 298 QLAEKKQQFRNLKERCFVTQLAGFLANQQKKYKYEECKDLIKSMLRNERQFKEEKLAEQL 357 Query: 339 TVAPRLSRGPLRVDKHE-----IPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQV 393 A L + + V E + ++ +G + S+ L P +D Q Sbjct: 358 KQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQGQDLQE 417 Query: 394 SLA--------LVDKIKKDQEEIED-----------QSPPCPRLSQELPEVKEQEVPEDS 434 LA LV K+ + + +D Q PR E+ + +E+EVPEDS Sbjct: 418 QLAEGCRLAQHLVQKLSPENDNDDDEDVQVELAEKVQKSSAPR---EMQKAEEKEVPEDS 474 Query: 435 VNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSAL 471 E +T S H D +QP+ T + E+ S L Sbjct: 475 QEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511 Score = 147 bits (371), Expect = 3e-35 Identities = 117/322 (36%), Positives = 162/322 (50%), Gaps = 20/322 (6%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D DE +K +EVE+ Q+ PR E+ +E EV QDSL+ C T S + QP+ Sbjct: 2625 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2684 Query: 228 STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275 S + +E + AL V+ EEEE PP + E E P Sbjct: 2685 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYS 2743 Query: 276 VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 P ++ +S + SF AL+E+ V + DV K + +K+ + Sbjct: 2744 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 2803 Query: 336 GQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392 G+E PRLSR L + E+ Q+SLD C TPS +L PY S +YS E++ Sbjct: 2804 GEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQY 2863 Query: 393 VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451 + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Y TPS + D Sbjct: 2864 LGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS 2923 Query: 452 HQPYSSTLSSLEDQLACSALDV 473 QPY S+ +LE++ +LDV Sbjct: 2924 CQPYGSSFYALEEKHVGFSLDV 2945 Score = 146 bits (368), Expect = 7e-35 Identities = 117/322 (36%), Positives = 162/322 (50%), Gaps = 20/322 (6%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D DE +K +EVE+ Q+ PR E+ +E EV QDSL+ C T S + QP+ Sbjct: 3864 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3923 Query: 228 STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275 S + +E + AL V+ EEEE PP + E E P Sbjct: 3924 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYS 3982 Query: 276 VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 P ++ +S + SF AL+E+ V + DV K + +K+ + Sbjct: 3983 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 4042 Query: 336 GQETVAP---RLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392 G+E P RLSR L E+ Q+SLD C TPS +LT S PY S Y E ++ Sbjct: 4043 GEEDQTPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR 4102 Query: 393 VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451 V LA+ +D+I+K QE EDQ P CPRLS+EL + KE EV +DS++ Y TPS + ++ D Sbjct: 4103 VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 4162 Query: 452 HQPYSSTLSSLEDQLACSALDV 473 QPYSS + SLE+Q ALDV Sbjct: 4163 GQPYSSAVYSLEEQYLGLALDV 4184 Score = 146 bits (368), Expect = 7e-35 Identities = 117/322 (36%), Positives = 162/322 (50%), Gaps = 20/322 (6%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D DE +K +EVE+ Q+ PR E+ +E EV QDSL+ C T S + QP+ Sbjct: 4108 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 4167 Query: 228 STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275 S + +E + AL V+ EEEE PP + E E P Sbjct: 4168 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYS 4226 Query: 276 VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 P ++ +S + SF AL+E+ V + DV K + +K+ + Sbjct: 4227 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 4286 Query: 336 GQE---TVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392 G+E PRLSR L E+ Q+SLD C TPS +LT S PY S Y E ++ Sbjct: 4287 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR 4346 Query: 393 VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451 V LA+ +D+I+K QE EDQ P CPRLS+EL + KE EV +DS++ Y TPS + ++ D Sbjct: 4347 VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 4406 Query: 452 HQPYSSTLSSLEDQLACSALDV 473 QPYSS + SLE+Q ALDV Sbjct: 4407 GQPYSSAVYSLEEQYLGLALDV 4428 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 748 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 807 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 808 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 867 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 868 LDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 918 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 919 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 971 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 972 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 1031 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 1032 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1068 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 992 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1051 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 1052 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1111 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 1112 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 1162 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 1163 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 1215 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 1216 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 1275 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 1276 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1312 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 1236 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1295 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 1296 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1355 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 1356 LDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 1406 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 1407 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 1459 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 1460 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 1519 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 1520 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1556 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 1480 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1539 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 1540 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1599 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 1600 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 1650 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 1651 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 1703 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 1704 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 1763 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 1764 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1800 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 1724 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1783 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 1784 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1843 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 1844 LDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 1894 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 1895 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 1947 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 1948 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2007 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 2008 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2044 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 1968 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2027 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 2028 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2087 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 2088 LDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 2138 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 2139 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2191 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 2192 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2251 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 2252 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2288 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 2212 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2271 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 2272 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2331 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 2332 LDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 2382 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 2383 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2435 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 2436 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2495 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 2496 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2532 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 2456 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2515 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 2516 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2575 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 2576 LDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 2626 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 2627 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2679 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 2680 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2739 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 2740 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2776 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 3207 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3266 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 3267 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 3326 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 3327 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 3377 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 3378 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 3430 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 3431 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 3490 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 3491 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3527 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 3451 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3510 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 3511 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 3570 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 3571 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 3621 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 3622 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 3674 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 3675 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 3734 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 3735 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3771 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 3695 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3754 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 3755 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 3814 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 3815 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 3865 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 3866 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 3918 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 3919 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 3978 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 3979 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 4015 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 4183 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 4242 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 4243 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 4302 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 4303 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 4353 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 4354 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 4406 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 4407 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 4466 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 4467 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 4503 Score = 143 bits (361), Expect = 4e-34 Identities = 114/323 (35%), Positives = 162/323 (50%), Gaps = 22/323 (6%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 3939 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3998 Query: 228 STKITFKEHEVDSALVV---ESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKS 284 S+ +E V +L V E + + + + E EE + P PR + Sbjct: 3999 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQTPPCPRLSREL 4058 Query: 285 NSYRHREVSFLALDE-----QKVCSAQDVARDYSNPKW--DETSLGF------LEKQSDL 331 + EV +LD D + Y + + ++ +G +EK ++ Sbjct: 4059 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDMDEIEKYQEV 4118 Query: 332 EEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDK 391 EE Q+ PRLSR L + E+ Q+SLD C TPS +L PY S +YS E++ Sbjct: 4119 EE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 4176 Query: 392 QVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSD 450 + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Y TPS + D Sbjct: 4177 YLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 4236 Query: 451 CHQPYSSTLSSLEDQLACSALDV 473 QPY S+ +LE++ +LDV Sbjct: 4237 SCQPYGSSFYALEEKHVGFSLDV 4259 Score = 140 bits (353), Expect = 4e-33 Identities = 113/314 (35%), Positives = 156/314 (49%), Gaps = 20/314 (6%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR E+ +E EV QDSL+ C T S + QP+ S + +E Sbjct: 2802 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 2861 Query: 236 HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------VPPRHHDK 283 + AL V+ EEEE PP + E E P P ++ Sbjct: 2862 QYLGLALDVDRTKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 2920 Query: 284 SNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETV--- 340 +S + SF AL+E+ V + DV K + +K+ +G+E Sbjct: 2921 PDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPP 2980 Query: 341 APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VD 399 PRLSR L + E+ Q+SLD C TPS +L PY S +YS E++ + LAL VD Sbjct: 2981 CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 3040 Query: 400 KIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTL 459 + KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Y TPS + D QPY S+ Sbjct: 3041 RTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 3100 Query: 460 SSLEDQLACSALDV 473 +LE++ +LDV Sbjct: 3101 YALEEKHVGFSLDV 3114 Score = 140 bits (353), Expect = 4e-33 Identities = 113/314 (35%), Positives = 156/314 (49%), Gaps = 20/314 (6%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR E+ +E EV QDSL+ C T S + QP+ S + +E Sbjct: 2971 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3030 Query: 236 HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------VPPRHHDK 283 + AL V+ EEEE PP + E E P P ++ Sbjct: 3031 QYLGLALDVDRTKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 3089 Query: 284 SNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETV--- 340 +S + SF AL+E+ V + DV K + +K+ +G+E Sbjct: 3090 PDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPP 3149 Query: 341 APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VD 399 PRLSR L + E+ Q+SLD C TPS +L PY S +YS E++ + LAL VD Sbjct: 3150 CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 3209 Query: 400 KIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTL 459 + KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Y TPS + D QPY S+ Sbjct: 3210 RTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 3269 Query: 460 SSLEDQLACSALDV 473 +LE++ +LDV Sbjct: 3270 YALEEKHVGFSLDV 3283 Score = 127 bits (318), Expect = 4e-29 Identities = 109/340 (32%), Positives = 158/340 (46%), Gaps = 37/340 (10%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 3038 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3097 Query: 228 STKITFKEHEVDSAL---VVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKS 284 S+ +E V +L +E + + + + E EE + P PR + Sbjct: 3098 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 3157 Query: 285 NSYRHREVSFLALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEE 333 + EV +LD D+ + YS+ + +E LG + D EE Sbjct: 3158 LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEE 3217 Query: 334 VKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQV 393 + Q PRLSR L V + E+ Q+SLD C TPS + S PY S+ Y+ E+K V Sbjct: 3218 EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHV 3277 Query: 394 SLAL-VDKIKKD-------------------QEEIEDQSPPCPRLSQELPEVKEQEVPED 433 +L V +I+K +E EDQ+PPCPRLS+EL + K EV +D Sbjct: 3278 GFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQD 3337 Query: 434 SVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 S++ Y TPS +++D QPY S LE Q A+D+ Sbjct: 3338 SLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM 3377 Score = 117 bits (293), Expect = 3e-26 Identities = 104/329 (31%), Positives = 151/329 (45%), Gaps = 50/329 (15%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR E+ + EV QDSL+ C T S ++S QP+RS ++ Sbjct: 4285 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 4344 Query: 236 HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFL 295 V A+ ++ E + E EE + P PR + + EV Sbjct: 4345 QRVGLAVDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQD 4388 Query: 296 ALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKGQETVAPRL 344 +LD D+ + YS+ + +E LG + D EE + Q PRL Sbjct: 4389 SLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRL 4448 Query: 345 SRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKK 403 SR L V + E+ Q+SLD C TPS + S PY S+ Y+ E+K V +L V +I+K Sbjct: 4449 SRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEK 4508 Query: 404 D-------------------QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSV 444 +E EDQ+PPCPRL+ L EV+E EV +DS++ Y TPS+ Sbjct: 4509 KGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSM 4568 Query: 445 HHDVSDCHQPYSSTLSSLEDQLACSALDV 473 + ++ D Q Y S S E+Q AL V Sbjct: 4569 YFELPDSFQHYRSVFYSFEEQHISFALYV 4597 Score = 117 bits (292), Expect = 4e-26 Identities = 104/329 (31%), Positives = 151/329 (45%), Gaps = 50/329 (15%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR E+ + EV QDSL+ C T S ++S QP+RS ++ Sbjct: 3797 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 3856 Query: 236 HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFL 295 V A+ ++ E + E EE + P PR + + EV Sbjct: 3857 QRVGLAVDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQD 3900 Query: 296 ALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKGQETVAPRL 344 +LD D+ + YS+ + +E LG + D EE + Q PRL Sbjct: 3901 SLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRL 3960 Query: 345 SRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKK 403 SR L V + E+ Q+SLD C TPS + S PY S+ Y+ E+K V +L V +I+K Sbjct: 3961 SRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEK 4020 Query: 404 D-------------------QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSV 444 +E EDQ+PPCPRLS+EL + K EV +DS++ Y TPS Sbjct: 4021 KGKGKKRRGRRSKKERRRGRKEGEEDQTPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSG 4080 Query: 445 HHDVSDCHQPYSSTLSSLEDQLACSALDV 473 +++D QPY S LE Q A+D+ Sbjct: 4081 CLELTDSCQPYRSAFYVLEQQRVGLAVDM 4109 Score = 40.8 bits (94), Expect = 0.004 Identities = 31/126 (24%), Positives = 56/126 (44%), Gaps = 19/126 (15%) Query: 348 PLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEE 407 P + ++ ++ +GC L ++ L+P ED+ V + +K++K Sbjct: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------EDEDEDVQVEEAEKVQKSS-- 186 Query: 408 IEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLA 467 PR E+ + +E +VPEDS+ E +T S H D +QP+ + + E+ Sbjct: 187 -------APR---EVQKTEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEV 236 Query: 468 CSALDV 473 S L V Sbjct: 237 NSTLVV 242 Score = 39.7 bits (91), Expect = 0.009 Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 3/71 (4%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR + + EE EV QDSL+ C T S +S Q +RS +F+E Sbjct: 4529 KEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEE 4588 Query: 236 HEVDSALVVES 246 + AL V++ Sbjct: 4589 QHISFALYVDN 4599 >gi|169162915 PREDICTED: hypothetical protein LOC728841 [Homo sapiens] Length = 3815 Score = 474 bits (1219), Expect = e-133 Identities = 276/499 (55%), Positives = 341/499 (68%), Gaps = 47/499 (9%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA PLSSE+AEMNILEIN++L QLAE QQFR+LKE+ +TQ + LANQ KKYK Sbjct: 21 MVVSAGPLSSEKAEMNILEINEKLHPQLAEKKQQFRNLKERCFVTQLAGF-LANQQKKYK 79 Query: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 EE KD+I S+LR+E Q EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDA Sbjct: 80 YEECKDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 139 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D+DED + E Sbjct: 140 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVE 197 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 EKVQ+S APRE+QK EEKEVP+DS EECA+T SNSH P +SNQPHR TKITF+E +VD Sbjct: 198 LAEKVQKSSAPREMQKAEEKEVPEDSQEECAITYSNSHGPYDSNQPHRKTKITFEEDKVD 257 Query: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285 S L+ S H E E+A++I PEN++D EEEE K PV PR+ +S Sbjct: 258 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 315 Query: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 SY+ +F +L+EQ+VC A D+ R +WD+ K+ D Sbjct: 316 TLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED----- 360 Query: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395 QE PRLSR L E+ Q+SLD C TPS +LT S PY S Y E +++ L Sbjct: 361 -QEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRIGL 419 Query: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454 A+ +D+I+K QE EDQ P CPRLS+EL + KE EV +DS++ Y TPS + ++ D QP Sbjct: 420 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 479 Query: 455 YSSTLSSLEDQLACSALDV 473 YSS + SLE+Q ALDV Sbjct: 480 YSSAVYSLEEQYLGLALDV 498 Score = 149 bits (375), Expect = 1e-35 Identities = 117/323 (36%), Positives = 164/323 (50%), Gaps = 22/323 (6%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 741 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 800 Query: 228 STKITFKEHEVDSALVV---ESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKS 284 S+ +E V +L V E + + + + E EE + P PR + Sbjct: 801 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 860 Query: 285 NSYRHREVSFLALDE-----QKVCSAQDVARDYSNPKW--DETSLGF------LEKQSDL 331 + EV +LD D+ + YS+ + +E LG +EK ++ Sbjct: 861 LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDEIEKYQEV 920 Query: 332 EEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDK 391 EE Q+ PRLSR L + E+ Q+SLD C TPS +L PY S +YS E++ Sbjct: 921 EE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 978 Query: 392 QVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSD 450 + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Y TPS + D Sbjct: 979 YLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 1038 Query: 451 CHQPYSSTLSSLEDQLACSALDV 473 QPY S+ +LE++ +LDV Sbjct: 1039 SCQPYGSSFYALEEKHVGFSLDV 1061 Score = 147 bits (371), Expect = 3e-35 Identities = 117/322 (36%), Positives = 162/322 (50%), Gaps = 20/322 (6%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D DE +K +EVE+ Q+ PR E+ +E EV QDSL+ C T S + QP+ Sbjct: 910 DVDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 969 Query: 228 STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275 S + +E + AL V+ EEEE PP + E E P Sbjct: 970 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYS 1028 Query: 276 VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 P ++ +S + SF AL+E+ V + DV K + +K+ + Sbjct: 1029 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 1088 Query: 336 GQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392 G+E PRLSR L + E+ Q+SLD C TPS +L PY S +YS E++ Sbjct: 1089 GEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQY 1148 Query: 393 VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451 + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Y TPS + D Sbjct: 1149 LGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS 1208 Query: 452 HQPYSSTLSSLEDQLACSALDV 473 QPY S+ +LE++ +LDV Sbjct: 1209 CQPYGSSFYALEEKHVGFSLDV 1230 Score = 147 bits (371), Expect = 3e-35 Identities = 117/322 (36%), Positives = 162/322 (50%), Gaps = 20/322 (6%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D DE +K +EVE+ Q+ PR E+ +E EV QDSL+ C T S + QP+ Sbjct: 2393 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2452 Query: 228 STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275 S + +E + AL V+ EEEE PP + E E P Sbjct: 2453 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYS 2511 Query: 276 VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 P ++ +S + SF AL+E+ V + DV K + +K+ + Sbjct: 2512 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 2571 Query: 336 GQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392 G+E PRLSR L + E+ Q+SLD C TPS +L PY S +YS E++ Sbjct: 2572 GEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQY 2631 Query: 393 VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451 + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Y TPS + D Sbjct: 2632 LGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS 2691 Query: 452 HQPYSSTLSSLEDQLACSALDV 473 QPY S+ +LE++ +LDV Sbjct: 2692 CQPYGSSFYALEEKHVGFSLDV 2713 Score = 147 bits (371), Expect = 3e-35 Identities = 117/322 (36%), Positives = 162/322 (50%), Gaps = 20/322 (6%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D DE +K +EVE+ Q+ PR E+ +E EV QDSL+ C T S + QP+ Sbjct: 2806 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2865 Query: 228 STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275 S + +E + AL V+ EEEE PP + E E P Sbjct: 2866 SAVYSLEEQYLGLALDVDRTKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYS 2924 Query: 276 VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 P ++ +S + SF AL+E+ V + DV K + +K+ + Sbjct: 2925 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 2984 Query: 336 GQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392 G+E PRLSR L + E+ Q+SLD C TPS +L PY S +YS E++ Sbjct: 2985 GEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQY 3044 Query: 393 VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451 + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Y TPS + D Sbjct: 3045 LGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDS 3104 Query: 452 HQPYSSTLSSLEDQLACSALDV 473 QPY S+ +LE++ +LDV Sbjct: 3105 CQPYGSSFYALEEKHVGFSLDV 3126 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 497 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 556 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 557 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 616 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 617 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 667 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 668 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 720 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 721 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 780 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 781 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 817 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 1492 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1551 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 1552 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1611 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 1612 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 1662 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 1663 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 1715 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 1716 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 1775 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 1776 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 1812 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 1736 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1795 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 1796 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1855 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 1856 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 1906 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 1907 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 1959 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 1960 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2019 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 2020 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2056 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 1980 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2039 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 2040 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2099 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 2100 LDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 2150 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 2151 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2203 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 2204 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2263 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 2264 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2300 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 2224 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2283 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 2284 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2343 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 2344 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 2394 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 2395 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2447 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 2448 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2507 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 2508 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2544 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 2637 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2696 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 2697 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2756 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 2757 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 2807 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 2808 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2860 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 2861 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2920 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 2921 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2957 Score = 144 bits (364), Expect = 2e-34 Identities = 119/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 3388 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3447 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 3448 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 3507 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 3508 LDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM--------- 3558 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 3559 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 3611 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+ KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 3612 GQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 3671 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 3672 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3708 Score = 140 bits (353), Expect = 4e-33 Identities = 113/314 (35%), Positives = 156/314 (49%), Gaps = 20/314 (6%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR E+ +E EV QDSL+ C T S + QP+ S + +E Sbjct: 1087 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 1146 Query: 236 HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------VPPRHHDK 283 + AL V+ EEEE PP + E E P P ++ Sbjct: 1147 QYLGLALDVDRTKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 1205 Query: 284 SNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETV--- 340 +S + SF AL+E+ V + DV K + +K+ +G+E Sbjct: 1206 PDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPP 1265 Query: 341 APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VD 399 PRLSR L + E+ Q+SLD C TPS +L PY S +YS E++ + LAL VD Sbjct: 1266 CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 1325 Query: 400 KIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTL 459 + KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Y TPS + D QPY S+ Sbjct: 1326 RTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 1385 Query: 460 SSLEDQLACSALDV 473 +LE++ +LDV Sbjct: 1386 YALEEKHVGFSLDV 1399 Score = 140 bits (353), Expect = 4e-33 Identities = 113/314 (35%), Positives = 156/314 (49%), Gaps = 20/314 (6%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR E+ +E EV QDSL+ C T S + QP+ S + +E Sbjct: 1256 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 1315 Query: 236 HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------VPPRHHDK 283 + AL V+ EEEE PP + E E P P ++ Sbjct: 1316 QYLGLALDVDRTKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 1374 Query: 284 SNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETV--- 340 +S + SF AL+E+ V + DV K + +K+ +G+E Sbjct: 1375 PDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPP 1434 Query: 341 APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VD 399 PRLSR L + E+ Q+SLD C TPS +L PY S +YS E++ + LAL VD Sbjct: 1435 CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 1494 Query: 400 KIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTL 459 + KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Y TPS + D QPY S+ Sbjct: 1495 RTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 1554 Query: 460 SSLEDQLACSALDV 473 +LE++ +LDV Sbjct: 1555 YALEEKHVGFSLDV 1568 Score = 140 bits (353), Expect = 4e-33 Identities = 113/314 (35%), Positives = 156/314 (49%), Gaps = 20/314 (6%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR E+ +E EV QDSL+ C T S + QP+ S + +E Sbjct: 2983 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3042 Query: 236 HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------VPPRHHDK 283 + AL V+ EEEE PP + E E P P ++ Sbjct: 3043 QYLGLALDVDRTKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 3101 Query: 284 SNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETV--- 340 +S + SF AL+E+ V + DV K + +K+ +G+E Sbjct: 3102 PDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPP 3161 Query: 341 APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VD 399 PRLSR L + E+ Q+SLD C TPS +L PY S +YS E++ + LAL VD Sbjct: 3162 CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 3221 Query: 400 KIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTL 459 + KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Y TPS + D QPY S+ Sbjct: 3222 RTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 3281 Query: 460 SSLEDQLACSALDV 473 +LE++ +LDV Sbjct: 3282 YALEEKHVGFSLDV 3295 Score = 140 bits (353), Expect = 4e-33 Identities = 113/314 (35%), Positives = 156/314 (49%), Gaps = 20/314 (6%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR E+ +E EV QDSL+ C T S + QP+ S + +E Sbjct: 3152 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 3211 Query: 236 HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------VPPRHHDK 283 + AL V+ EEEE PP + E E P P ++ Sbjct: 3212 QYLGLALDVDRTKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQ 3270 Query: 284 SNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETV--- 340 +S + SF AL+E+ V + DV K + +K+ +G+E Sbjct: 3271 PDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPP 3330 Query: 341 APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VD 399 PRLSR L + E+ Q+SLD C TPS +L PY S +YS E++ + LAL VD Sbjct: 3331 CPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVD 3390 Query: 400 KIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTL 459 + KKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Y TPS + D QPY S+ Sbjct: 3391 RTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSF 3450 Query: 460 SSLEDQLACSALDV 473 +LE++ +LDV Sbjct: 3451 YALEEKHVGFSLDV 3464 Score = 127 bits (318), Expect = 4e-29 Identities = 109/340 (32%), Positives = 158/340 (46%), Gaps = 37/340 (10%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 1323 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1382 Query: 228 STKITFKEHEVDSAL---VVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKS 284 S+ +E V +L +E + + + + E EE + P PR + Sbjct: 1383 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1442 Query: 285 NSYRHREVSFLALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEE 333 + EV +LD D+ + YS+ + +E LG + D EE Sbjct: 1443 LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEE 1502 Query: 334 VKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQV 393 + Q PRLSR L V + E+ Q+SLD C TPS + S PY S+ Y+ E+K V Sbjct: 1503 EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHV 1562 Query: 394 SLAL-VDKIKKD-------------------QEEIEDQSPPCPRLSQELPEVKEQEVPED 433 +L V +I+K +E EDQ+PPCPRLS+EL + K EV +D Sbjct: 1563 GFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQD 1622 Query: 434 SVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 S++ Y TPS +++D QPY S LE Q A+D+ Sbjct: 1623 SLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM 1662 Score = 126 bits (317), Expect = 5e-29 Identities = 109/340 (32%), Positives = 158/340 (46%), Gaps = 37/340 (10%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 3219 DVDRTKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3278 Query: 228 STKITFKEHEVDSAL---VVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKS 284 S+ +E V +L +E + + + + E EE + P PR + Sbjct: 3279 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 3338 Query: 285 NSYRHREVSFLALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEE 333 + EV +LD D+ + YS+ + +E LG + D EE Sbjct: 3339 LDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEE 3398 Query: 334 VKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQV 393 + Q PRLSR L V + E+ Q+SLD C TPS + S PY S+ Y+ E+K V Sbjct: 3399 EEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHV 3458 Query: 394 SLAL-VDKIKKD-------------------QEEIEDQSPPCPRLSQELPEVKEQEVPED 433 +L V +I+K +E EDQ+PPCPRLS+EL + K EV +D Sbjct: 3459 GFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQD 3518 Query: 434 SVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 S++ Y TPS +++D QPY S LE Q A+D+ Sbjct: 3519 SLDRSYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVDM 3558 Score = 113 bits (282), Expect = 6e-25 Identities = 103/329 (31%), Positives = 150/329 (45%), Gaps = 50/329 (15%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR E+ + EV QDSL+ T S ++S QP+RS ++ Sbjct: 3490 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRSYSTPSGCLELTDSCQPYRSAFYVLEQ 3549 Query: 236 HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFL 295 V A+ ++ E + E EE + P PR + + EV Sbjct: 3550 QRVGLAVDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQD 3593 Query: 296 ALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKGQETVAPRL 344 +LD D+ + YS+ + +E LG + D EE + Q PRL Sbjct: 3594 SLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRTKKDQEEEEDQGPPCPRL 3653 Query: 345 SRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKK 403 SR L V + E+ Q+SLD C TPS + S PY S+ Y+ E+K V +L V +I+K Sbjct: 3654 SRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEK 3713 Query: 404 D-------------------QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSV 444 +E EDQ+PPCPRLS+EL + K EV +DS++ Y TPS Sbjct: 3714 KGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSG 3773 Query: 445 HHDVSDCHQPYSSTLSSLEDQLACSALDV 473 +++D QPY S LE Q A+D+ Sbjct: 3774 CLELTDSCQPYRSAFYVLEQQRVGLAVDM 3802 Score = 37.0 bits (84), Expect = 0.056 Identities = 24/73 (32%), Positives = 38/73 (52%), Gaps = 3/73 (4%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR E+ + EV QDSL+ C T S ++S QP+RS ++ Sbjct: 3734 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 3793 Query: 236 HEVDSALVVESEH 248 V A+ ++ E+ Sbjct: 3794 QRVGLAVDMDGEY 3806 >gi|92110019 hypothetical protein LOC55672 [Homo sapiens] Length = 1214 Score = 472 bits (1214), Expect = e-133 Identities = 277/499 (55%), Positives = 337/499 (67%), Gaps = 47/499 (9%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA PLSSE+AEMNILE+N++LR QLAE QQFR+LKEK +TQ + LANQ KYK Sbjct: 543 MVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLACF-LANQQNKYK 601 Query: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 EE KD+I SVLR+E Q EKLAE+L+QAEELRQYK LVHSQ +ELTQLREKLREGRDA Sbjct: 602 YEECKDLIKSVLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 661 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+ L KLSPEND D DED + E Sbjct: 662 SRSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQQLFQKLSPENDNDHDEDV--QVE 719 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 EKVQ+S APRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPHR TKITF+E +VD Sbjct: 720 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVD 779 Query: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285 S L+ S H E E+A++I PEN++D EEEE K PV PR+ +S Sbjct: 780 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 837 Query: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 SY+ +F +L+EQ+VC A D+ +WD+ K+ D Sbjct: 838 TLSIPPEMLASYQSYSGTFHSLEEQQVCMAVDI----GGHRWDQV------KKED----- 882 Query: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395 QE PRLSR L E+ Q+SLD C TPS +LT S PY S Y E ++V Sbjct: 883 -QEATGPRLSRELLDEKGPEVLQDSLDRCYSTPSGYLELTDSCQPYRSAFYILEQQRVGW 941 Query: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454 AL +D+I+K QE EDQ P CPRLS+EL + KE EV +DS++ Y TPS + ++ D QP Sbjct: 942 ALDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 1001 Query: 455 YSSTLSSLEDQLACSALDV 473 Y S + SLE+Q ALDV Sbjct: 1002 YRSAVYSLEEQYLGLALDV 1020 Score = 363 bits (931), Expect = e-100 Identities = 235/520 (45%), Positives = 305/520 (58%), Gaps = 58/520 (11%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA PLSSE+AEMNILE+N++LR QLAE QQFR+LKEK +TQ + LANQ KYK Sbjct: 272 MVVSAGPLSSEKAEMNILEMNEKLRPQLAEKKQQFRNLKEKCFVTQLAGF-LANQQNKYK 330 Query: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 EE +D+I S+LR+E Q EKLAE+L+QAEELRQYK LVHSQ +ELTQLREKLREGRDA Sbjct: 331 YEECEDLIKSMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 390 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPENDEDEDED + E Sbjct: 391 SRSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDV--QVE 448 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 E EKV ES APREVQK EE +VP+DSLEECA+TCSNSH P +SNQPH++ ITF+E +V+ Sbjct: 449 EAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVN 508 Query: 240 SALVVESEHPHDEEEEALNIPP---------------------ENQNDHEEEEGKAPVPP 278 SALVV+ E HDE ++A+NI P + + E + P Sbjct: 509 SALVVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRP 568 Query: 279 RHHDKSNSYRH-REVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQ 337 + +K +R+ +E F+ Q C + Y + + L + +E K Sbjct: 569 QLAEKKQQFRNLKEKCFVT---QLACFLANQQNKYKYEECKDLIKSVLRNERQFKEEKLA 625 Query: 338 ETV--APRLSRGPLRVDKHE-----IPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFED 390 E + A L + + V E + ++ +G + S+ L P +D Sbjct: 626 EQLKQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQD 685 Query: 391 KQVSLA--------LVDKIKKDQEEIED-----------QSPPCPRLSQELPEVKEQEVP 431 Q LA L K+ + + D Q PR E+ + +E+EVP Sbjct: 686 LQEQLAEGCRLAQQLFQKLSPENDNDHDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVP 742 Query: 432 EDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSAL 471 EDS+ E +T S H D +QP+ T + E+ S L Sbjct: 743 EDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTL 782 Score = 359 bits (921), Expect = 5e-99 Identities = 233/516 (45%), Positives = 308/516 (59%), Gaps = 46/516 (8%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA P SSE+AE NILEIN++LR QLAE+ QQFR+LKEK +TQ + LAN+ KKYK Sbjct: 1 MVVSAGPWSSEKAETNILEINEKLRPQLAENKQQFRNLKEKCFVTQLAGF-LANRQKKYK 59 Query: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 EE KD+I +LR+E Q EKLAE+L+QAEELRQYK LVHSQ +ELTQLREKLREGRDA Sbjct: 60 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPENDEDEDED + E Sbjct: 120 SRSLNQHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDV--QVE 177 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 E EKV ES APREVQK EE +VP+DSLEECA+TCSNSH P +SNQPH++ ITF+E +V+ Sbjct: 178 EAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKVN 237 Query: 240 SALVVESEHPHDEEEEALNIPP--------------ENQNDHEEEEGKAPVPPRHHDKSN 285 S LVV+ E HDE ++A+NI P + E+ + + + Sbjct: 238 STLVVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEKLRP 297 Query: 286 SYRHREVSFLALDEQKVCS--AQDVARDYSNPKWDE-----TSLGFLEKQSDLEEVKGQE 338 ++ F L E+ + A +A + K++E S+ E+Q E++ Q Sbjct: 298 QLAEKKQQFRNLKEKCFVTQLAGFLANQQNKYKYEECEDLIKSMLRNERQFKEEKLAEQL 357 Query: 339 TVAPRLSRGPLRVDKHE-----IPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQV 393 A L + + V E + ++ +G + S+ L P +D Q Sbjct: 358 KQAEELRQYKVLVHSQERELTQLREKLREGRDASRSLNQHLQALLTPDEPDKSQGQDLQE 417 Query: 394 SLA--------LVDKIKKDQEEIEDQSPPCPRLS--------QELPEVKEQEVPEDSVNE 437 LA LV K+ + +E ED+ +E+ + +E +VPEDS+ E Sbjct: 418 QLAEGCRLAQHLVQKLSPENDEDEDEDVQVEEAEKVLESSAPREVQKAEESKVPEDSLEE 477 Query: 438 VYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 +T S H D +QP+ + + E+ SAL V Sbjct: 478 CAITCSNSHGPCDSNQPHKNINITFEEDKVNSALVV 513 Score = 40.4 bits (93), Expect = 0.005 Identities = 55/247 (22%), Positives = 102/247 (41%), Gaps = 49/247 (19%) Query: 348 PLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEE 407 P + ++ ++ +GC L ++ L+P ED+ V + +K+ Sbjct: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------EDEDEDVQVEEAEKV------ 182 Query: 408 IEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPY------------ 455 +E +P +E+ + +E +VPEDS+ E +T S H D +QP+ Sbjct: 183 LESSAP------REVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNINITFEEDKV 236 Query: 456 SSTL------SSLEDQLACSALDVASPTEAA--CPQGTWSGDLSHHQSEVQVSQAQLEPS 507 +STL S E Q A + L V PT +A +G LS ++E+ + + + Sbjct: 237 NSTLVVDRESSHDECQDAVNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEMNEK-- 294 Query: 508 TLVPSCLRLQLDQGFHCGNGLAQRGLSSTTCSFSANADSGNQWPFQELVLEPSLGMKNPP 567 LR QL + L ++ + F AN N++ ++E ++N Sbjct: 295 ------LRPQLAEKKQQFRNLKEKCFVTQLAGFLANQQ--NKYKYEECEDLIKSMLRNER 346 Query: 568 QLEDDAL 574 Q +++ L Sbjct: 347 QFKEEKL 353 Score = 39.7 bits (91), Expect = 0.009 Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 3/71 (4%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR + + EE EV QDSL+ C T S +S Q +RS +F+E Sbjct: 1122 KEGEEDQNPPCPRLSGMLMEVEEPEVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEE 1181 Query: 236 HEVDSALVVES 246 + AL V++ Sbjct: 1182 QHISFALDVDN 1192 >gi|83415174 hypothetical protein LOC400818 [Homo sapiens] Length = 942 Score = 470 bits (1209), Expect = e-132 Identities = 289/547 (52%), Positives = 355/547 (64%), Gaps = 54/547 (9%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA PLSSE+AEMNILEIN++LR QLAE QQFR+LKEK +TQ + LANQ KYK Sbjct: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANQQNKYK 330 Query: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 EE KD+I +LR+E Q EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDA Sbjct: 331 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDA 390 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D++ED + E Sbjct: 391 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDV--QVE 448 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 EKVQ+S APRE+QK EEKEVP+DSLEECA+T SNSH P +SNQPHR TKITF+E +VD Sbjct: 449 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVD 508 Query: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285 S L+ S H E E+A++I PEN++D EEEE K PV PR+ +S Sbjct: 509 STLIGSSSHV--EREDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 566 Query: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 SY+ +F +L+EQ+VC A D+ R +WD+ K+ D Sbjct: 567 TPSIPPEMLASYKSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED----- 611 Query: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395 QE PRLSR L E+ Q+SL C TPS +LT S PY S Y E ++V L Sbjct: 612 -QEATGPRLSRELLDEKGPEVLQDSLYRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGL 670 Query: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454 A+ +D+I+K QE EDQ P CPRLS+EL + KE EV +DS+ Y TPS + ++ D QP Sbjct: 671 AVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRWYSTPSGYPELPDLGQP 730 Query: 455 YSSTLSSLEDQLACSALD---VASPTEAACPQGTWSGDLSHHQSEV---QVSQAQLEPST 508 YSS + SLE+Q ALD + E QG LS EV +V Q L+ Sbjct: 731 YSSAVYSLEEQYLGLALDLDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCY 790 Query: 509 LVP-SCL 514 P SCL Sbjct: 791 STPSSCL 797 Score = 358 bits (920), Expect = 6e-99 Identities = 240/523 (45%), Positives = 313/523 (59%), Gaps = 64/523 (12%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA P SSE+AEMNILEIN++LR QLAE+ QQF +LKE+ +TQ + LAN+ KKYK Sbjct: 1 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFGNLKERCFLTQLAGF-LANRQKKYK 59 Query: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 EE KD+I +LR+E Q EKLAE+L+QAEELRQYK LVHSQ +ELTQL+EKLREGRDA Sbjct: 60 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLKEKLREGRDA 119 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPENDEDEDED + E Sbjct: 120 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDV--QVE 177 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 E EKV ESPAPREVQK EE +V +DSLEECA+TCSNSH P +SNQPH++ KITF+E EV+ Sbjct: 178 EDEKVLESPAPREVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVN 237 Query: 240 SALVVESEHPHDEEEEALNIPP---------------------ENQNDHEEEEGKAPVPP 278 S LVV+ E HDE ++ALNI P + + E + P Sbjct: 238 STLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRP 297 Query: 279 RHHDKSNSYRH-REVSFLALDEQKVCSAQDVARDYSNPKWDETS--LGFL---EKQSDLE 332 + +K +R+ +E FL A +A + K++E + F+ E+Q E Sbjct: 298 QLAEKKQQFRNLKEKCFLTQ------LAGFLANQQNKYKYEECKDLIKFMLRNERQFKEE 351 Query: 333 EVKGQETVAPRLSRGPLRVDKHE-----IPQESLDGCCLTPSILPDLTPSYHPYWSTLYS 387 ++ Q A L + + V E + ++ +G + S+ L P Sbjct: 352 KLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQALLTPDEPDKSQ 411 Query: 388 FEDKQVSLA--------LVDKI--KKDQEEIED---------QSPPCPRLSQELPEVKEQ 428 +D Q LA LV K+ + D ++ ED Q PR E+ + +E+ Sbjct: 412 GQDLQEQLAEGCRLAQHLVQKLSPENDNDDNEDVQVEVAEKVQKSSAPR---EMQKAEEK 468 Query: 429 EVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSAL 471 EVPEDS+ E +T S H D +QP+ T + E+ S L Sbjct: 469 EVPEDSLEECAITYSNSHGPYDSNQPHRKTKITFEEDKVDSTL 511 Score = 40.4 bits (93), Expect = 0.005 Identities = 54/247 (21%), Positives = 104/247 (42%), Gaps = 49/247 (19%) Query: 348 PLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEE 407 P + ++ ++ +GC L ++ L+P ED+ V ++++D++ Sbjct: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------EDEDEDV------QVEEDEKV 182 Query: 408 IEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPY------------ 455 +E +P +E+ + +E +V EDS+ E +T S H D +QP+ Sbjct: 183 LESPAP------REVQKAEESKVTEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEV 236 Query: 456 SSTL------SSLEDQLACSALDVASPTEAA--CPQGTWSGDLSHHQSEVQVSQAQLEPS 507 +STL S E Q A + L V PT +A +G LS ++E+ + + Sbjct: 237 NSTLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILE------ 290 Query: 508 TLVPSCLRLQLDQGFHCGNGLAQRGLSSTTCSFSANADSGNQWPFQELVLEPSLGMKNPP 567 + LR QL + L ++ + F AN N++ ++E ++N Sbjct: 291 --INEKLRPQLAEKKQQFRNLKEKCFLTQLAGFLANQQ--NKYKYEECKDLIKFMLRNER 346 Query: 568 QLEDDAL 574 Q +++ L Sbjct: 347 QFKEEKL 353 Score = 39.7 bits (91), Expect = 0.009 Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 3/71 (4%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR + + EE EV QDSL+ C T S +S Q +RS +F+E Sbjct: 850 KEGEEDQNPPCPRLNGVLMEVEEPEVLQDSLDGCYSTPSMYFELPDSFQHYRSVFYSFEE 909 Query: 236 HEVDSALVVES 246 + AL V++ Sbjct: 910 QHISFALYVDN 920 >gi|224589132 hypothetical protein LOC100132406 [Homo sapiens] Length = 3628 Score = 468 bits (1203), Expect = e-131 Identities = 275/499 (55%), Positives = 340/499 (68%), Gaps = 47/499 (9%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA PLSSE+AEMNILEIN++LR QLAE QQFR+LKEK +TQ + + LANQ KKYK Sbjct: 272 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRNLKEKCFLTQLSGF-LANQQKKYK 330 Query: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 EE KD+I +LR+E Q EKLAE+L+QAEELRQYK LVH+Q +ELTQL+EKLREGRDA Sbjct: 331 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDA 390 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 SR LN+HL+ LLTP +PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D+DED + E Sbjct: 391 SRSLNEHLQALLTPYEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVE 448 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 EKVQ+S APRE+QK EEKEVP+DSLEECA+T SNSH +SNQPHR TKITF+E +VD Sbjct: 449 VAEKVQKSSAPREMQKAEEKEVPEDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVD 508 Query: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN-------------- 285 S L+ S H E E+A++I PEN++D EEEE K PV PR+ +S Sbjct: 509 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYS 566 Query: 286 ----------SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 SY+ +F +L+EQ+VC A D+ R +WD+ K+ D Sbjct: 567 TLSIPPEMLASYQSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED----- 611 Query: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395 QE PRLSR L E+ Q+S D C TPS +LT S PY S Y E ++V L Sbjct: 612 -QEATGPRLSRELLDEKGPEVFQDSQDRCYSTPSGCLELTDSCQPYRSAFYILEQQRVGL 670 Query: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454 A+ +D+I+K QE EDQ P CPRLS+EL + KE EV +DS++ Y TPS + ++ D QP Sbjct: 671 AIDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQP 730 Query: 455 YSSTLSSLEDQLACSALDV 473 YSS + SLE+Q ALDV Sbjct: 731 YSSAVYSLEEQYLGLALDV 749 Score = 363 bits (932), Expect = e-100 Identities = 236/520 (45%), Positives = 304/520 (58%), Gaps = 58/520 (11%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA P SSE+AEMNILEIN+ LR QLAE QQFR+LKEK +TQ + LAN+ KKYK Sbjct: 1 MVVSAGPWSSEKAEMNILEINETLRPQLAEKKQQFRNLKEKCFLTQLAGF-LANRQKKYK 59 Query: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 EE KD+I +LR+E Q EKLAE+L+QAEELRQYK LVHSQ +ELTQLREKLREGRDA Sbjct: 60 YEECKDLIKFMLRNERQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 SR L +HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPENDEDEDED + E Sbjct: 120 SRSLYEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDEDEDEDV--QVE 177 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 E EKV ES APREVQK EE +VP+DSLEECA+TCSNSH P +SNQPH++ KITF+E EV+ Sbjct: 178 EAEKVLESSAPREVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEVN 237 Query: 240 SALVVESEHPHDEEEEALNIPP---------------------ENQNDHEEEEGKAPVPP 278 S LVV+ E HDE ++ALNI P + + E + P Sbjct: 238 STLVVDRESSHDECQDALNILPVPGPTSSATNVSMVVSAGPLSSEKAEMNILEINEKLRP 297 Query: 279 RHHDKSNSYRH-REVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQ 337 + +K +R+ +E FL + + Q + Y + + L + +E K Sbjct: 298 QLAEKKQQFRNLKEKCFLTQLSGFLANQQ---KKYKYEECKDLIKFMLRNERQFKEEKLA 354 Query: 338 ETVAPRLSRGPLRVDKH-------EIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFED 390 E + +V H ++ ++ +G + S+ L PY +D Sbjct: 355 EQLKQAEELRQYKVLVHAQERELTQLKEKLREGRDASRSLNEHLQALLTPYEPDKSQGQD 414 Query: 391 KQVSLA--------LVDKIKKDQEEIED-----------QSPPCPRLSQELPEVKEQEVP 431 Q LA LV K+ + + +D Q PR E+ + +E+EVP Sbjct: 415 LQEQLAEGCRLAQHLVQKLSPENDNDDDEDVQVEVAEKVQKSSAPR---EMQKAEEKEVP 471 Query: 432 EDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSAL 471 EDS+ E +T S H D +QP+ T + E+ S L Sbjct: 472 EDSLEECAITYSNSHGSYDSNQPHRKTKITFEEDKVDSTL 511 Score = 150 bits (378), Expect = 5e-36 Identities = 119/322 (36%), Positives = 164/322 (50%), Gaps = 20/322 (6%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D DE +K +EVE+ Q+ PR E+ +E EV QDSL+ C T S + QP+ Sbjct: 1161 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 1220 Query: 228 STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275 S + +E + AL V+ DEEEE PP + E E AP Sbjct: 1221 SAVYSLEEQYLGLALDVD-RIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYS 1279 Query: 276 VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 P ++ +S + SF AL+E+ V + DV K + +K+ + Sbjct: 1280 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 1339 Query: 336 GQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392 G+E PRLSR L E+ Q+SLD C TPS +LT S PY S Y E ++ Sbjct: 1340 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR 1399 Query: 393 VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451 V +A+ +D+I+K QE EDQ P CPRLS+EL + KE EV +DS+N Y TPS + ++ D Sbjct: 1400 VGMAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDL 1459 Query: 452 HQPYSSTLSSLEDQLACSALDV 473 QPYSS + SLE+Q ALDV Sbjct: 1460 GQPYSSAVYSLEEQYLGLALDV 1481 Score = 146 bits (368), Expect = 7e-35 Identities = 116/323 (35%), Positives = 164/323 (50%), Gaps = 22/323 (6%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 748 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 807 Query: 228 STKITFKEHEVDSALVV---ESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKS 284 S+ +E V +L V E + + + + E EE + P PR + Sbjct: 808 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 867 Query: 285 NSYRHREVSFLALDE-----QKVCSAQDVARDYSNPKW--DETSLGF------LEKQSDL 331 + EV +LD D + Y + + ++ +GF +EK ++ Sbjct: 868 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGFAVDMDEIEKYQEV 927 Query: 332 EEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDK 391 EE Q+ PRLSR L + E+ Q+SLD C TPS +L PY S +YS E++ Sbjct: 928 EE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQ 985 Query: 392 QVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSD 450 + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Y TPS + D Sbjct: 986 YLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPD 1045 Query: 451 CHQPYSSTLSSLEDQLACSALDV 473 QPY S+ +LE++ +LDV Sbjct: 1046 SCQPYGSSFYALEEKHVGFSLDV 1068 Score = 146 bits (368), Expect = 7e-35 Identities = 119/339 (35%), Positives = 169/339 (49%), Gaps = 50/339 (14%) Query: 169 DEDEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQP 225 D D + D++EE ++ Q+ P PR E+ + E EV QDSL+ C T S+ +S QP Sbjct: 1480 DVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQP 1539 Query: 226 HRSTKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQN 265 + S+ +E+ V +L V E E EE N P P Sbjct: 1540 YGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSR 1599 Query: 266 DHEEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNP 315 + +E+G + P + ++S + +F L++Q V A D+ Sbjct: 1600 ELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM------- 1652 Query: 316 KWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLT 375 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 1653 --DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELP 1703 Query: 376 PSYHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDS 434 PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS Sbjct: 1704 DLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDS 1763 Query: 435 VNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 ++ Y TPS + D QPY S+ +LE+ +LDV Sbjct: 1764 LDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 1802 Score = 145 bits (366), Expect = 1e-34 Identities = 120/337 (35%), Positives = 167/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 2458 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2517 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E+ V +L V E E EE N P P + Sbjct: 2518 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2577 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q V A D+ Sbjct: 2578 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM--------- 2628 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 2629 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2681 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 2682 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2741 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 2742 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 2778 Score = 145 bits (365), Expect = 1e-34 Identities = 120/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 1726 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1785 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E+ V +L V E E EE N P P + Sbjct: 1786 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1845 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q V A D+ Sbjct: 1846 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM--------- 1896 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 1897 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 1949 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 1950 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2009 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE+ +LDV Sbjct: 2010 RCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2046 Score = 145 bits (365), Expect = 1e-34 Identities = 120/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 1970 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2029 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E+ V +L V E E EE N P P + Sbjct: 2030 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2089 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q V A D+ Sbjct: 2090 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM--------- 2140 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 2141 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2193 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 2194 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2253 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE+ +LDV Sbjct: 2254 RCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2290 Score = 145 bits (365), Expect = 1e-34 Identities = 120/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 2214 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2273 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E+ V +L V E E EE N P P + Sbjct: 2274 SSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2333 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q V A D+ Sbjct: 2334 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM--------- 2384 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 2385 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2437 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 2438 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2497 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE+ +LDV Sbjct: 2498 RCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 2534 Score = 144 bits (364), Expect = 2e-34 Identities = 117/322 (36%), Positives = 160/322 (49%), Gaps = 20/322 (6%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D DE +K +EVE+ Q+ PR E+ +E EV QDSL+ C T S + QP+ Sbjct: 2139 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 2198 Query: 228 STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275 S + +E + AL V+ EEEE PP + E E P Sbjct: 2199 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYS 2257 Query: 276 VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 P ++ +S + SF AL+E V + DV K + +K+ + Sbjct: 2258 TPSSCLEQPDSCQPYGSSFYALEENHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 2317 Query: 336 GQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392 G+E PRLSR L E+ Q+SLD C TPS +LT S PY S Y E + Sbjct: 2318 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQH 2377 Query: 393 VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451 V LA+ +D+I+K QE EDQ P CPRLS+EL + KE EV +DS++ Y TPS + ++ D Sbjct: 2378 VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2437 Query: 452 HQPYSSTLSSLEDQLACSALDV 473 QPYSS + SLE+Q ALDV Sbjct: 2438 GQPYSSAVYSLEEQYLGLALDV 2459 Score = 144 bits (364), Expect = 2e-34 Identities = 120/337 (35%), Positives = 166/337 (49%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 2702 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 2761 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 2762 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 2821 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q V A D+ Sbjct: 2822 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQHVGLAVDM--------- 2872 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 2873 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 2925 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 PY S +YS E++ + LAL VD+IKKDQEE EDQ PPCPRLS+EL EV E EV +DS++ Sbjct: 2926 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLD 2985 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS + D QPY S+ +LE++ +LDV Sbjct: 2986 RCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 3022 Score = 144 bits (362), Expect = 3e-34 Identities = 116/322 (36%), Positives = 161/322 (50%), Gaps = 20/322 (6%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D DE +K +EVE+ Q+ PR E+ +E EV QDSL+ C T S + QP+ Sbjct: 917 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 976 Query: 228 STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275 S + +E + AL V+ EEEE PP + E E P Sbjct: 977 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYS 1035 Query: 276 VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 P ++ +S + SF AL+E+ V + DV K + +K+ + Sbjct: 1036 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 1095 Query: 336 GQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392 G+E PRLSR L E+ Q+SLD C TPS +LT S PY S Y E ++ Sbjct: 1096 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQR 1155 Query: 393 VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451 V A+ +D+I+K QE EDQ P CPRLS+EL + KE EV +DS++ Y TPS + ++ D Sbjct: 1156 VGFAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 1215 Query: 452 HQPYSSTLSSLEDQLACSALDV 473 QPYSS + SLE+Q ALDV Sbjct: 1216 GQPYSSAVYSLEEQYLGLALDV 1237 Score = 142 bits (359), Expect = 7e-34 Identities = 116/322 (36%), Positives = 160/322 (49%), Gaps = 20/322 (6%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D DE +K +EVE+ Q+ PR E+ +E EV QDSL+ C T S + QP+ Sbjct: 3190 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYS 3249 Query: 228 STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP------------ 275 S + +E + AL V+ EEEE PP + E E P Sbjct: 3250 SAVYSLEEQYLGLALDVDRIKKDQEEEEDQG-PPCPRLSRELLEVVEPEVLQDSLDRCYS 3308 Query: 276 VPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 P ++ +S + SF AL+E+ V + DV K + +K+ + Sbjct: 3309 TPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKE 3368 Query: 336 GQETV---APRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQ 392 G+E PRLSR L E+ Q+SLD C TPS +L S PY S Y E + Sbjct: 3369 GEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQH 3428 Query: 393 VSLAL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDC 451 V LA+ +D+I+K QE EDQ P CPRLS+EL + KE EV +DS++ Y TPS + ++ D Sbjct: 3429 VGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 3488 Query: 452 HQPYSSTLSSLEDQLACSALDV 473 QPYSS + SLE+Q ALDV Sbjct: 3489 GQPYSSAVYSLEEQYLGLALDV 3510 Score = 139 bits (350), Expect = 8e-33 Identities = 119/339 (35%), Positives = 166/339 (48%), Gaps = 52/339 (15%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KDEE E+ Q+ P PR E+ + EV QDSL+ C T S+ +S QP+ Sbjct: 1236 DVDRIKKDEEEEEDQDPPCPRLSRELLEVVAPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 1295 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 1296 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 1355 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + ++S + +F L++Q+V A D+ Sbjct: 1356 LDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGMAVDM--------- 1406 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SL+ C TPS +L Sbjct: 1407 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLNRCYSTPSGYLELPDL 1459 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKDQ--EEIEDQSPPCPRLSQELPEVKEQEVPEDS 434 PY S +YS E++ + LAL VD+IKKDQ EE EDQ PPCPRLS+EL EV E EV +DS Sbjct: 1460 GQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDEDQDPPCPRLSRELLEVVEPEVLQDS 1519 Query: 435 VNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 ++ Y TPS + D QPY S+ +LE+ +LDV Sbjct: 1520 LDRCYSTPSSCLEQPDSCQPYGSSFYALEENHVGFSLDV 1558 Score = 139 bits (350), Expect = 8e-33 Identities = 110/310 (35%), Positives = 160/310 (51%), Gaps = 31/310 (10%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR E+ + +V QDSL+ C T S +S QP+RS ++ Sbjct: 3048 KEGEEDQNPPCPRLSRELLDEKGPKVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQ 3107 Query: 236 HEVDSALVVESEHPHDEEEEALNIP-PENQNDHEEEEGKAPV----------PPRHHDKS 284 V A+ ++ + E EE + P + +E+G + P + Sbjct: 3108 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELC 3167 Query: 285 NSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRL 344 +S + +F L++Q+V A D+ DE +EK ++EE Q+ PRL Sbjct: 3168 DSCQPYRSAFYILEQQRVGLAVDM---------DE-----IEKYQEVEE--DQDPSCPRL 3211 Query: 345 SRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKK 403 SR L + E+ Q+SLD C TPS +L PY S +YS E++ + LAL VD+IKK Sbjct: 3212 SRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 3271 Query: 404 DQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLE 463 DQEE EDQ PPCPRLS+EL EV E EV +DS++ Y TPS + D QPY S+ +LE Sbjct: 3272 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 3331 Query: 464 DQLACSALDV 473 ++ +LDV Sbjct: 3332 EKHVGFSLDV 3341 Score = 123 bits (309), Expect = 5e-28 Identities = 115/356 (32%), Positives = 163/356 (45%), Gaps = 69/356 (19%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D D KD+E E+ Q P PR E+ + E EV QDSL+ C T S+ +S QP+ Sbjct: 3265 DVDRIKKDQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYG 3324 Query: 228 STKITFKEHEVDSALVV-------------------ESEHPHDEEEEALNIP-PENQNDH 267 S+ +E V +L V E E EE N P P + Sbjct: 3325 SSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSREL 3384 Query: 268 EEEEGKAPV----------PPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKW 317 +E+G + P + +S + +F L++Q V A D+ Sbjct: 3385 LDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDM--------- 3435 Query: 318 DETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPS 377 DE +EK ++EE Q+ PRLSR L + E+ Q+SLD C TPS +L Sbjct: 3436 DE-----IEKYQEVEE--DQDPSCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDL 3488 Query: 378 YHPYWSTLYSFEDKQVSLAL-VDKIKKD-------------------QEEIEDQSPPCPR 417 PY S +YS E++ + LAL VDKI+K +E EDQ+PPCPR Sbjct: 3489 GQPYSSAVYSLEEQYLGLALDVDKIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPR 3548 Query: 418 LSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 L+ L EV+E+EV +DS++ Y TPS++ ++ D Q Y S S E+Q AL V Sbjct: 3549 LNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEEQHISFALYV 3604 Score = 120 bits (302), Expect = 3e-27 Identities = 108/337 (32%), Positives = 155/337 (45%), Gaps = 50/337 (14%) Query: 171 DEDEDDKDEEVEKVQESPAP---REVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D DE +K +EVE+ Q+ P RE+ + EV QDSL+ C T S +S QP+R Sbjct: 3115 DMDEIEKYQEVEEDQDPSCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELCDSCQPYR 3174 Query: 228 STKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSY 287 S ++ V A+ ++ E + E EE + P PR + Sbjct: 3175 SAFYILEQQRVGLAVDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDE 3218 Query: 288 RHREVSFLALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKG 336 + EV +LD D+ + YS+ + +E LG + D EE + Sbjct: 3219 KEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEED 3278 Query: 337 QETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLA 396 Q PRLSR L V + E+ Q+SLD C TPS + S PY S+ Y+ E+K V + Sbjct: 3279 QGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFS 3338 Query: 397 L-VDKIKKD-------------------QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVN 436 L V +I+K +E EDQ+PPCPRLS+EL + K EV +DS++ Sbjct: 3339 LDVGEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLD 3398 Query: 437 EVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 Y TPS ++ D QPY S LE Q A+D+ Sbjct: 3399 RCYSTPSGCLELCDSCQPYRSAFYVLEQQHVGLAVDM 3435 Score = 116 bits (290), Expect = 7e-26 Identities = 104/329 (31%), Positives = 151/329 (45%), Gaps = 50/329 (15%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR E+ + EV QDSL+ C T S ++S QP+RS ++ Sbjct: 850 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQ 909 Query: 236 HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFL 295 V A+ ++ E + E EE + P PR + + EV Sbjct: 910 QRVGFAVDMD----------------EIEKYQEVEEDQDPSCPRLSRELLDEKEPEVLQD 953 Query: 296 ALDE-----QKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKGQETVAPRL 344 +LD D+ + YS+ + +E LG + D EE + Q PRL Sbjct: 954 SLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGPPCPRL 1013 Query: 345 SRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKK 403 SR L V + E+ Q+SLD C TPS + S PY S+ Y+ E+K V +L V +I+K Sbjct: 1014 SRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDVGEIEK 1073 Query: 404 D-------------------QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSV 444 +E EDQ+PPCPRLS+EL + K EV +DS++ Y TPS Sbjct: 1074 KGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSG 1133 Query: 445 HHDVSDCHQPYSSTLSSLEDQLACSALDV 473 +++D QPY S LE Q A+D+ Sbjct: 1134 CLELTDSCQPYRSAFYVLEQQRVGFAVDM 1162 Score = 41.6 bits (96), Expect = 0.002 Identities = 26/71 (36%), Positives = 39/71 (54%), Gaps = 3/71 (4%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR + + EE+EV QDSL+ C T S +S Q +RS +F+E Sbjct: 3536 KEGEEDQNPPCPRLNGVLMEVEEREVLQDSLDRCYSTPSMYFELPDSFQHYRSVFYSFEE 3595 Query: 236 HEVDSALVVES 246 + AL V++ Sbjct: 3596 QHISFALYVDN 3606 Score = 40.0 bits (92), Expect = 0.007 Identities = 30/126 (23%), Positives = 57/126 (45%), Gaps = 19/126 (15%) Query: 348 PLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEE 407 P + ++ ++ +GC L ++ L+P ED+ V + +K+ Sbjct: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------EDEDEDVQVEEAEKV------ 182 Query: 408 IEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLA 467 +E +P +E+ + +E +VPEDS+ E +T S H D +QP+ + + E+ Sbjct: 183 LESSAP------REVQKAEESKVPEDSLEECAITCSNSHGPCDSNQPHKNIKITFEEDEV 236 Query: 468 CSALDV 473 S L V Sbjct: 237 NSTLVV 242 >gi|14149997 neuroblastoma breakpoint family, member 3 [Homo sapiens] Length = 633 Score = 459 bits (1182), Expect = e-129 Identities = 268/499 (53%), Positives = 336/499 (67%), Gaps = 47/499 (9%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA P S E+AEMNILEIN++ R QLAE+ QQFR+LK+K L+TQ AY LAN+ Y Sbjct: 57 MVVSAGPWSGEKAEMNILEINKKSRPQLAENKQQFRNLKQKCLVTQV-AYFLANRQNNYD 115 Query: 61 CEEYKDIIDSVLRDE-LQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 E+ KD+I S+LRDE L + EKLAE+L QAEELRQYK LVHSQ +ELTQLREKL+EGRDA Sbjct: 116 YEDCKDLIKSMLRDERLLTEEKLAEELGQAEELRQYKVLVHSQERELTQLREKLQEGRDA 175 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 SR LN+HL+ LLTPD+PD SQG+DLREQLAEG RLA+HLV KLSPEND+DEDED K E Sbjct: 176 SRSLNQHLQALLTPDEPDNSQGRDLREQLAEGCRLAQHLVQKLSPENDDDEDEDV--KVE 233 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 E EKVQE APREVQK EEKEVP+DSLEECA+TCSNSH+P SNQP+ +T+ITF+E +VD Sbjct: 234 EAEKVQELYAPREVQKAEEKEVPEDSLEECAITCSNSHHPCESNQPYGNTRITFEEDQVD 293 Query: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRH------------------- 280 S L+ S HDE +A+ I PEN++DHE+EE K PV PR+ Sbjct: 294 STLIDSSS--HDEWLDAVCIIPENESDHEQEEEKGPVSPRNLQESEEEEAPQESWDEGDW 351 Query: 281 -----HDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVK 335 D S SY+ +F +++EQ+V A D+ R + D + + Sbjct: 352 TLSIPPDMSASYQSDRSTFHSVEEQQVGLALDIGRHW----------------CDQVKKE 395 Query: 336 GQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSL 395 QE +PRLSR L + E+ Q+SLD TP +L PY S YS +++ + L Sbjct: 396 DQEATSPRLSRELLDEKEPEVLQDSLDRFYSTPFEYLELPDLCQPYRSDFYSLQEQHLGL 455 Query: 396 AL-VDKIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQP 454 AL +D++KKDQEE EDQ PPCPRLS+ELPEV E E +DS++ Y TP + ++ D QP Sbjct: 456 ALDLDRMKKDQEEEEDQGPPCPRLSRELPEVVEPEDLQDSLDRWYSTPFSYPELPDSCQP 515 Query: 455 YSSTLSSLEDQLACSALDV 473 Y S SLE++ +LDV Sbjct: 516 YGSCFYSLEEEHVGFSLDV 534 Score = 48.5 bits (114), Expect = 2e-05 Identities = 31/79 (39%), Positives = 44/79 (55%), Gaps = 3/79 (3%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D DE +K +E E+ Q+ P PR + + EE EV QDSL+ C T S S Q +R Sbjct: 533 DVDEIEKYQEGEEDQKPPCPRLNEVLMEAEEPEVLQDSLDRCYSTTSTYFQLHASFQQYR 592 Query: 228 STKITFKEHEVDSALVVES 246 S +F+E +V AL V++ Sbjct: 593 SAFYSFEEQDVSLALDVDN 611 >gi|114158664 hypothetical protein LOC343505 [Homo sapiens] Length = 421 Score = 416 bits (1069), Expect = e-116 Identities = 236/399 (59%), Positives = 281/399 (70%), Gaps = 39/399 (9%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA P SSE+AEMNILEIN++LR QLAE+ QQFR++K+KFL+TQ + LANQ KYK Sbjct: 21 MVVSAGPWSSEKAEMNILEINEKLRPQLAENKQQFRNMKQKFLVTQMAGF-LANQQNKYK 79 Query: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 EE KD+I S+LR+ELQ EKLAE+L+QAEELRQYK LVHSQ +EL QLREKLREGRDA Sbjct: 80 YEECKDLIKSMLREELQFKEEKLAEQLKQAEELRQYKVLVHSQERELIQLREKLREGRDA 139 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 S LN+HL+ LLTPD D SQGQD REQLAEG RLA HLVHKLSPEND DEDE+ DK + Sbjct: 140 SHSLNQHLQALLTPDKHDNSQGQDFREQLAEGCRLARHLVHKLSPENDTDEDEN--DKTK 197 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 E++KVQESPAPRE QK EEKEVP+DSLEECA+T SNSH PS+SN PH++ KIT +E +V+ Sbjct: 198 ELDKVQESPAPREEQKAEEKEVPEDSLEECAITYSNSHGPSDSNPPHKNIKITSEEDKVN 257 Query: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR-------------------- 279 S LVV+SE DE ++ALNI ENQND EEEEGKAPVPP+ Sbjct: 258 SILVVDSESSQDEWQDALNILLENQNDDEEEEGKAPVPPQVTLWICGLKLQESEEKEVLQ 317 Query: 280 ------------HHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEK 327 HD S SY+ E +FLAL EQKVCSAQDVA ++SN K +ET LGF + Sbjct: 318 DSPEERVTTSCSDHDVSQSYQPCEGTFLALVEQKVCSAQDVASEHSNSKGEETPLGFPDT 377 Query: 328 Q---SDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDG 363 + D ++ + + VA L IP +L G Sbjct: 378 KYCWKDEKDERMSQKVAFLLDEKNYNSKPSSIPNTTLQG 416 Score = 69.7 bits (169), Expect = 8e-12 Identities = 68/253 (26%), Positives = 110/253 (43%), Gaps = 39/253 (15%) Query: 250 HDEEEEALNIPPENQNDHEEEEG-----KAPVPPRHHDKSNSYRHREVSFLALDEQKVCS 304 H +E E + + + + + +A + P HD S RE ++ Sbjct: 120 HSQERELIQLREKLREGRDASHSLNQHLQALLTPDKHDNSQGQDFRE---------QLAE 170 Query: 305 AQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGC 364 +AR + E E E K QE+ APR + + ++ E+P++SL+ C Sbjct: 171 GCRLARHLVHKLSPENDTDEDENDKTKELDKVQESPAPREEQ---KAEEKEVPEDSLEEC 227 Query: 365 CLTPSILPDLTPSYHPYWST-LYSFEDKQVSLALVD----------------KIKKDQEE 407 +T S + S P+ + + S EDK S+ +VD + + D EE Sbjct: 228 AITYSNSHGPSDSNPPHKNIKITSEEDKVNSILVVDSESSQDEWQDALNILLENQNDDEE 287 Query: 408 IEDQSPPCPRLSQ-----ELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSL 462 E ++P P+++ +L E +E+EV +DS E T HDVS +QP T +L Sbjct: 288 EEGKAPVPPQVTLWICGLKLQESEEKEVLQDSPEERVTTSCSDHDVSQSYQPCEGTFLAL 347 Query: 463 EDQLACSALDVAS 475 +Q CSA DVAS Sbjct: 348 VEQKVCSAQDVAS 360 >gi|7657017 hypothetical protein LOC25832 [Homo sapiens] Length = 921 Score = 395 bits (1016), Expect = e-110 Identities = 231/429 (53%), Positives = 286/429 (66%), Gaps = 46/429 (10%) Query: 71 VLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDASRWLNKHLKT 129 +LR+E Q EKLAE+L+QAEELRQYK LVH+Q +ELTQLREKLREGRDASR LN+HL+ Sbjct: 1 MLRNERQFKEEKLAEQLKQAEELRQYKVLVHAQERELTQLREKLREGRDASRSLNEHLQA 60 Query: 130 LLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEKVQESPA 189 LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D+DED + E EKVQ+S A Sbjct: 61 LLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVEVAEKVQKSSA 118 Query: 190 PREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVVESEHP 249 PRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPHR TKITF+E +VDS L+ S H Sbjct: 119 PREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVDSTLIGSSSHV 178 Query: 250 HDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN------------------------ 285 E E+A++I PEN++D EEEE K PV PR+ +S Sbjct: 179 --EWEDAVHIIPENESDDEEEEEKGPVSPRNLQESEEEEVPQESWDEGYSTLSIPPEMLA 236 Query: 286 SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLS 345 SY+ +F +L+EQ+VC A D+ R +WD+ K+ D E PRLS Sbjct: 237 SYKSYSSTFHSLEEQQVCMAVDIGRH----RWDQV------KKED------HEATGPRLS 280 Query: 346 RGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKKD 404 R L E+ Q+SLD C TPS +LT S PY S Y E ++V LA+ +D+I+K Sbjct: 281 RELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYVLEQQRVGLAVNMDEIEKY 340 Query: 405 QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLED 464 QE EDQ P CPRLS+EL + KE EV +DS+ Y TPS + ++ D QPYSS + SLE+ Sbjct: 341 QEVEEDQDPSCPRLSRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEE 400 Query: 465 QLACSALDV 473 Q ALDV Sbjct: 401 QYLGLALDV 409 Score = 138 bits (348), Expect = 1e-32 Identities = 109/310 (35%), Positives = 159/310 (51%), Gaps = 31/310 (10%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR E+ + EV QDSL+ C T S ++S QP+RS ++ Sbjct: 510 KEGEEDQNPPCPRLSRELLDEKGPEVLQDSLDRCYSTPSGCLELTDSCQPYRSAFYILEQ 569 Query: 236 HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDK-----------S 284 V A+ ++ + E EE + + +E + V D+ + Sbjct: 570 QRVGLAVDMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELT 629 Query: 285 NSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRL 344 +S + +F L++Q+V A D+ DE +EK ++EE Q+ PRL Sbjct: 630 DSCQPYRSAFYILEQQRVGLAVDM---------DE-----IEKYQEVEE--DQDPSCPRL 673 Query: 345 SRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-VDKIKK 403 SR L + E+ Q+SL C TPS +L PY S +YS E++ + LAL VD+IKK Sbjct: 674 SRELLDEKEPEVLQDSLGRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDRIKK 733 Query: 404 DQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLE 463 DQEE EDQ PPCPRLS+EL EV E EV +DS++ Y TPS + D QPY S+ +LE Sbjct: 734 DQEEEEDQGPPCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALE 793 Query: 464 DQLACSALDV 473 ++ +LDV Sbjct: 794 EKHVGFSLDV 803 Score = 122 bits (306), Expect = 1e-27 Identities = 105/334 (31%), Positives = 161/334 (48%), Gaps = 44/334 (13%) Query: 171 DEDEDDKDEEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHR 227 D DE +K +EVE+ Q+ PR E+ +E EV Q+SL+ C T S ++S QP+R Sbjct: 577 DMDEIEKYQEVEEDQDPSCPRLSGELLDEKEPEVLQESLDRCYSTPSGCLELTDSCQPYR 636 Query: 228 STKITFKEHEVDSALVVES--EHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSN 285 S ++ V A+ ++ ++ EE++ + P ++ +E+E P D Sbjct: 637 SAFYILEQQRVGLAVDMDEIEKYQEVEEDQDPSCPRLSRELLDEKE-----PEVLQDSLG 691 Query: 286 SYRHREVSFLALDEQKVCSAQDVARDYSNPKW--DETSLGFL----EKQSDLEEVKGQET 339 +L L D+ + YS+ + +E LG + D EE + Q Sbjct: 692 RCYSTPSGYLELP--------DLGQPYSSAVYSLEEQYLGLALDVDRIKKDQEEEEDQGP 743 Query: 340 VAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-V 398 PRLSR L V + E+ Q+SLD C TPS + S PY S+ Y+ E+K V +L V Sbjct: 744 PCPRLSRELLEVVEPEVLQDSLDRCYSTPSSCLEQPDSCQPYGSSFYALEEKHVGFSLDV 803 Query: 399 DKIKKD-------------------QEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVY 439 +I+K +E EDQ+PPCPRL+ L EV+E EV +DS++ Y Sbjct: 804 GEIEKKGKGKKRRGRRSKKERRRGRKEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICY 863 Query: 440 LTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDV 473 TPS++ ++ D Q Y S S E++ AL V Sbjct: 864 STPSMYFELPDSFQHYRSVFYSFEEEHISFALYV 897 Score = 39.3 bits (90), Expect = 0.011 Identities = 26/71 (36%), Positives = 38/71 (53%), Gaps = 3/71 (4%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR + + EE EV QDSL+ C T S +S Q +RS +F+E Sbjct: 829 KEGEEDQNPPCPRLNSMLMEVEEPEVLQDSLDICYSTPSMYFELPDSFQHYRSVFYSFEE 888 Query: 236 HEVDSALVVES 246 + AL V++ Sbjct: 889 EHISFALYVDN 899 >gi|239741297 PREDICTED: neuroblastoma breakpoint family, member 9 [Homo sapiens] Length = 299 Score = 368 bits (945), Expect = e-102 Identities = 196/280 (70%), Positives = 228/280 (81%), Gaps = 6/280 (2%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 MVVSA PLSSE+AEMNILEIN++LR QLAE QQFR LKEK +TQ + LA Q KYK Sbjct: 1 MVVSAGPLSSEKAEMNILEINEKLRPQLAEKKQQFRSLKEKCFVTQLAGF-LAKQQNKYK 59 Query: 61 CEEYKDIIDSVLRDELQ-SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 EE KD+I S+LR+ELQ EKLAE+L+QAEELRQYK LVHSQ +ELTQLREKLREGRDA Sbjct: 60 YEECKDLIKSMLRNELQFKEEKLAEQLKQAEELRQYKVLVHSQERELTQLREKLREGRDA 119 Query: 120 SRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDE 179 SR LN+HL+ LLTPD+PDKSQGQDL+EQLAEG RLA+HLV KLSPEND D+DED + E Sbjct: 120 SRSLNEHLQALLTPDEPDKSQGQDLQEQLAEGCRLAQHLVQKLSPENDNDDDEDV--QVE 177 Query: 180 EVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVD 239 EKVQ+S +PRE+QK EEKEVP+DSLEECA+TCSNSH P +SNQPHR TKITF+E +VD Sbjct: 178 VAEKVQKSSSPREMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVD 237 Query: 240 SALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR 279 S L+ S H E E+A++I PEN++D EEEE K PV PR Sbjct: 238 STLIGSSSHV--EWEDAVHIIPENESDDEEEEEKGPVSPR 275 Score = 45.1 bits (105), Expect = 2e-04 Identities = 31/124 (25%), Positives = 58/124 (46%), Gaps = 19/124 (15%) Query: 348 PLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEE 407 P + ++ ++ +GC L ++ L+P + +D+ V + + +K++K Sbjct: 136 PDKSQGQDLQEQLAEGCRLAQHLVQKLSPEND-------NDDDEDVQVEVAEKVQKSSS- 187 Query: 408 IEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLA 467 PR E+ + +E+EVPEDS+ E +T S H D +QP+ T + E+ Sbjct: 188 --------PR---EMQKAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKV 236 Query: 468 CSAL 471 S L Sbjct: 237 DSTL 240 Score = 36.2 bits (82), Expect = 0.095 Identities = 25/100 (25%), Positives = 49/100 (49%), Gaps = 18/100 (18%) Query: 335 KGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQV- 393 K Q++ +PR + + ++ E+P++SL+ C +T S S P+ T +FE+ +V Sbjct: 181 KVQKSSSPREMQ---KAEEKEVPEDSLEECAITCSNSHGPYDSNQPHRKTKITFEEDKVD 237 Query: 394 --------------SLALVDKIKKDQEEIEDQSPPCPRLS 419 ++ ++ + + D EE E++ P PR S Sbjct: 238 STLIGSSSHVEWEDAVHIIPENESDDEEEEEKGPVSPRTS 277 >gi|239747446 PREDICTED: similar to Neuroblastoma breakpoint family member 6-like protein [Homo sapiens] Length = 298 Score = 145 bits (365), Expect = 1e-34 Identities = 86/185 (46%), Positives = 114/185 (61%), Gaps = 8/185 (4%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 M VSA RAEM+ILE NQ LRS+L + Q F+DL EKFL ++ATAYSL N L+KYK Sbjct: 1 MAVSATTCFGPRAEMSILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60 Query: 61 CEEYKDIIDSVLRDELQSMEK-LAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 CEE KD+I+SVL +E+Q E+ LAE R A LR + L+ +QA+ELT LR+K++EGR Sbjct: 61 CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKIQEGRGV 120 Query: 120 SRWLNKHLKT-------LLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDE 172 +H+K LL D Q Q EQ+ +G +L E LV KL+ EN + Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180 Query: 173 DEDDK 177 ++ K Sbjct: 181 EDRQK 185 >gi|239741304 PREDICTED: similar to Neuroblastoma breakpoint family member 6-like protein [Homo sapiens] Length = 298 Score = 142 bits (358), Expect = 9e-34 Identities = 85/185 (45%), Positives = 113/185 (61%), Gaps = 8/185 (4%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 M VSA RAE++ILE NQ LRS+L + Q F+DL EKFL ++ATAYSL N L+KYK Sbjct: 1 MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60 Query: 61 CEEYKDIIDSVLRDELQSMEK-LAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 CEE KD+I+SVL +E+Q E+ LAE R A LR + L+ +QA+ELT LR+K +EGR Sbjct: 61 CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120 Query: 120 SRWLNKHLKT-------LLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDE 172 +H+K LL D Q Q EQ+ +G +L E LV KL+ EN + Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180 Query: 173 DEDDK 177 ++ K Sbjct: 181 EDRQK 185 >gi|239741281 PREDICTED: Neuroblastoma breakpoint family member 6-like protein [Homo sapiens] Length = 322 Score = 142 bits (358), Expect = 9e-34 Identities = 85/185 (45%), Positives = 113/185 (61%), Gaps = 8/185 (4%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 M VSA RAE++ILE NQ LRS+L + Q F+DL EKFL ++ATAYSL N L+KYK Sbjct: 1 MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60 Query: 61 CEEYKDIIDSVLRDELQSMEK-LAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 CEE KD+I+SVL +E+Q E+ LAE R A LR + L+ +QA+ELT LR+K +EGR Sbjct: 61 CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120 Query: 120 SRWLNKHLKT-------LLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDE 172 +H+K LL D Q Q EQ+ +G +L E LV KL+ EN + Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTDIAYYQRQRFCEQMVQGSQLTEILVRKLATENHNGKKN 180 Query: 173 DEDDK 177 ++ K Sbjct: 181 EDRQK 185 >gi|239752894 PREDICTED: Neuroblastoma breakpoint family member 6-like protein [Homo sapiens] Length = 298 Score = 138 bits (348), Expect = 1e-32 Identities = 84/185 (45%), Positives = 111/185 (60%), Gaps = 8/185 (4%) Query: 1 MVVSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK 60 M VSA RAE++ILE NQ LRS+L + Q F+DL EKFL ++ATAYSL N L+KYK Sbjct: 1 MAVSATTCFGPRAEISILETNQYLRSELEKCKQNFQDLTEKFLTSKATAYSLTNHLQKYK 60 Query: 61 CEEYKDIIDSVLRDELQSMEK-LAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDA 119 CEE KD+I+SVL +E+Q E+ LAE R A LR + L+ +QA+ELT LR+K +EGR Sbjct: 61 CEECKDLIESVLEEEVQFQERELAELPRSAARLRIHDPLIQAQAEELTHLRQKTQEGRGV 120 Query: 120 SRWLNKHLKT-------LLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDE 172 +H+K LL Q Q EQ+ +G +L E LV KL EN + Sbjct: 121 CYLFTQHVKNTVKSFEGLLRNTGIAYYQRQRFCEQMVQGSQLTEILVRKLVTENHNGKKN 180 Query: 173 DEDDK 177 ++ K Sbjct: 181 EDRQK 185 >gi|157311604 phosphodiesterase 4D interacting protein isoform 1 [Homo sapiens] Length = 2346 Score = 96.7 bits (239), Expect = 6e-20 Identities = 69/185 (37%), Positives = 102/185 (55%), Gaps = 14/185 (7%) Query: 80 EKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDASRWLNKHLK-------TLLT 132 EKLAE+LR A +Y +L+ QA+EL+ LR+K+REGR + +H K LL Sbjct: 1459 EKLAEELRSASWPGKYDSLIQDQARELSYLRQKIREGRGICYLITRHAKDTVKSFEDLLR 1518 Query: 133 PDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEKVQESPAPRE 192 +D D GQ REQLA+G +L E L KLS ++ + E KD+ + RE Sbjct: 1519 SNDIDYYLGQSFREQLAQGSQLTERLTSKLSTKDHKSE------KDQAGLEPLALRLSRE 1572 Query: 193 VQKTEEK-EVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVVESEHPHD 251 +Q+ E+ EV Q L+ ++T S+SH S+S++ ST E E S + + SE+ H Sbjct: 1573 LQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSSTSFLSDELEACSDMDIVSEYTHY 1632 Query: 252 EEEEA 256 EE++A Sbjct: 1633 EEKKA 1637 Score = 66.2 bits (160), Expect = 9e-11 Identities = 61/196 (31%), Positives = 79/196 (40%), Gaps = 44/196 (22%) Query: 480 ACPQGTWSGDLSHHQSEVQVSQAQLEPSTLVPSCLRLQLDQGFHCGNGLAQRGLSSTTCS 539 AC Q S DLSH +EV+ + QLE S +CLRLQL Q G G A SS + Sbjct: 2034 ACHQIPLSSDLSHLVAEVRALRGQLEQSIQGNNCLRLQLQQQLESGAGKASLSPSSINQN 2093 Query: 540 FSANADSGNQW----------PFQE------------------------------LVLEP 559 F A+ D GN+ P ++ L L+ Sbjct: 2094 FPASTDPGNKQLLLQDSAVSPPVRDVGMNSPALVFPSSASSTPGSETPIINRANGLGLDT 2153 Query: 560 SLGMKNPPQLEDDALEGSASNTQGRQVTGRIRASLVLILKTIRRRLPFSK----WRLAFR 615 S MK PP+LE DA +GS +N GR V G I L + +L K R A Sbjct: 2154 SPVMKTPPKLEGDATDGSFANKHGRHVIGHIDDYSALRQQIAEGKLLVKKIVSLVRSACS 2213 Query: 616 FAGPHAESAEIPNTAG 631 F G A+ E+ + G Sbjct: 2214 FPGLEAQGTEVLGSKG 2229 Score = 62.4 bits (150), Expect = 1e-09 Identities = 117/485 (24%), Positives = 191/485 (39%), Gaps = 102/485 (21%) Query: 22 QELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYK--------CEEYKDIIDSVLR 73 Q LRSQL++ Q+++DL+EK L+++AT ++ AN+L+KY+ ++ I L+ Sbjct: 1214 QHLRSQLSQCKQRYQDLQEKLLLSEATVFAQANELEKYRVMLTGESLVKQDSKQIQVDLQ 1273 Query: 74 DELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLR----EKLREGRD-ASRWLNKHLK 128 D +E + EE + H+ KE+ + E+ R G AS K L+ Sbjct: 1274 DLGYETCGRSENEAEREETTSPECEEHNSLKEMVLMEGLCSEQGRRGSTLASSSERKPLE 1333 Query: 129 TLLTPDDPDKSQG------------QDLREQLAEGHRLAEHL---VHKLSPENDEDEDED 173 L + + G +DL+ QL +++ ++L V LS +D + Sbjct: 1334 NQLGKQEEFRVYGKSENILVLRKDIKDLKAQLQNANKVIQNLKSRVRSLSVTSDYSSSLE 1393 Query: 174 EDDKDEEVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITF 233 K V + E +P V +E + S P K Sbjct: 1394 RPWKLRAVGTL-EGSSPHSVPDEDEGWL--------------SDGTGAFYSPGLQAKKDL 1438 Query: 234 KEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVS 293 E + +E++ P + EE L EE ++ P +D + RE+S Sbjct: 1439 -ESLIQRVSQLEAQLPKNGLEEKL-----------AEELRSASWPGKYDSLIQDQARELS 1486 Query: 294 FLALDEQKVCSAQDVARDYSNPKWDET-SLGFLEKQSDLEEVKGQETVAPRLSRGPLRVD 352 +L QK+ + + + D S L + +D++ GQ Sbjct: 1487 YL---RQKIREGRGICYLITRHAKDTVKSFEDLLRSNDIDYYLGQ--------------- 1528 Query: 353 KHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEEIEDQS 412 ++ G LT + L+ H K +KDQ +E Sbjct: 1529 --SFREQLAQGSQLTERLTSKLSTKDH--------------------KSEKDQAGLE--- 1563 Query: 413 PPCPRLSQELPE-VKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQL-ACSA 470 P RLS+EL E K EV + ++ LTPS H +SD H+ SST S L D+L ACS Sbjct: 1564 PLALRLSRELQEKEKVIEVLQAKLDARSLTPSSSHALSDSHRSPSST-SFLSDELEACSD 1622 Query: 471 LDVAS 475 +D+ S Sbjct: 1623 MDIVS 1627 Score = 33.1 bits (74), Expect = 0.80 Identities = 67/332 (20%), Positives = 132/332 (39%), Gaps = 44/332 (13%) Query: 11 ERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLK---KYKCEEYKDI 67 E + +I + N EL+ ++ ++ +D K+ T A +L +Q + + + EE + Sbjct: 38 EASREDIYKRNIELKVEVESLKRELQDKKQHLDKTWADVENLNSQNEAELRRQFEERQQE 97 Query: 68 IDSVLRDELQSMEKLAEKLRQAE-ELRQYKALVHSQAKELTQLREKLREGRDASRWLNKH 126 + V ++ L E+ R A+ E + ALV ++ + +L EKL+ + K+ Sbjct: 98 TEHVYELLENKIQLLQEESRLAKNEAARMAALVEAEKECNLELSEKLKG-------VTKN 150 Query: 127 LKTL----LTPDDPDKSQGQ-DLR-EQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEE 180 + + + PD ++ Q D R E+L + E LV +LS E + E+ E Sbjct: 151 WEDVPGDQVKPDQYTEALAQRDKRIEELNQSLAAQERLVEQLSREKQQLLHLLEEPTSME 210 Query: 181 VEKVQESPAPREVQKTEEKEVPQDSLEECAVT----------CSNSHNPSNSNQPHRSTK 230 V+ + E ++ + E + Q S+ + + +N N+ K Sbjct: 211 VQPMTEELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYELK 270 Query: 231 ITFKEHEVDSALV---VESEHPHDEEEEALNIPPENQND---------HEEEEGKAPVPP 278 + + + E+ + E E L E QND H+ + G+ Sbjct: 271 CAQESSQKQDGTIQNLKETLKSRERETEELYQVIEGQNDTMAKLREMLHQSQLGQL---- 326 Query: 279 RHHDKSNSYRHREVSFLALDEQKVCSAQDVAR 310 H + S ++V+ L L CS ++ + Sbjct: 327 -HSSEGTSPAQQQVALLDLQSALFCSQLEIQK 357 Score = 32.0 bits (71), Expect = 1.8 Identities = 29/120 (24%), Positives = 55/120 (45%), Gaps = 11/120 (9%) Query: 3 VSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLK----K 58 + P++ E + L ++ +Q + S+ +L+EK T+AT L +L + Sbjct: 209 MEVQPMTEELLKQQKLNSHETTITQQSVSDSHLAELQEKIQQTEATNKILQEKLNEMSYE 268 Query: 59 YKC-EEYKDIIDSVLRDELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGR 117 KC +E D +++ E L + R+ EEL Q ++ Q + +LRE L + + Sbjct: 269 LKCAQESSQKQDGTIQN---LKETLKSRERETEELYQ---VIEGQNDTMAKLREMLHQSQ 322 >gi|239758011 PREDICTED: hypothetical protein LOC728841, partial [Homo sapiens] Length = 166 Score = 80.1 bits (196), Expect = 6e-15 Identities = 50/119 (42%), Positives = 68/119 (57%), Gaps = 20/119 (16%) Query: 377 SYHPYWSTLYSFEDKQVSLAL-VDKIKKD-------------------QEEIEDQSPPCP 416 S PY S+ Y+ E+K V +L V +I+K +E EDQ+PPCP Sbjct: 6 SCQPYGSSFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCP 65 Query: 417 RLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSSTLSSLEDQLACSALDVAS 475 RLS+EL + KE EV +DS++ Y TPS + ++ D QPYSS + SLE+Q ALDV S Sbjct: 66 RLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLALDVDS 124 Score = 47.4 bits (111), Expect = 4e-05 Identities = 37/108 (34%), Positives = 53/108 (49%), Gaps = 3/108 (2%) Query: 293 SFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETV---APRLSRGPL 349 SF AL+E+ V + DV K + +K+ +G+E PRLSR L Sbjct: 13 SFYALEEKHVGFSLDVGEIEKKGKGKKRRGRRSKKKRRRGRKEGEEDQNPPCPRLSRELL 72 Query: 350 RVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL 397 + E+ Q+SLD C TPS +L PY S +YS E++ + LAL Sbjct: 73 DEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEEQYLGLAL 120 Score = 38.9 bits (89), Expect = 0.015 Identities = 26/73 (35%), Positives = 38/73 (52%), Gaps = 3/73 (4%) Query: 179 EEVEKVQESPAPR---EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 +E E+ Q P PR E+ +E EV QDSL+ C T S + QP+ S + +E Sbjct: 54 KEGEEDQNPPCPRLSRELLDEKEPEVLQDSLDRCYSTPSGYLELPDLGQPYSSAVYSLEE 113 Query: 236 HEVDSALVVESEH 248 + AL V+SE+ Sbjct: 114 QYLGLALDVDSEY 126 >gi|222418637 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 750 Score = 58.9 bits (141), Expect = 1e-08 Identities = 66/327 (20%), Positives = 130/327 (39%), Gaps = 28/327 (8%) Query: 11 ERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYKCEEYKDIIDS 70 E ++ E QE +++ ++ R+ +EK + + ++ K E + I + Sbjct: 415 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR-----QEEKIHEQEKIREE 469 Query: 71 VLRDELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDASRWLNKHLKTL 130 R E + M + EK+ + EE+ + K +H Q +++ + EK+ + R + ++ Sbjct: 470 EKRQEQEEMWRQEEKIHEQEEIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIR-- 527 Query: 131 LTPDDPDKSQGQDLREQLAEGHRLAE--HLVHKLSPENDEDEDEDEDDKDEEVEKVQESP 188 ++ Q + +REQ E R E H K+ E E ED+ + EE + QE Sbjct: 528 -EQEEKMWRQEEKIREQ-EEMWREEEKMHEQEKIWEEEKRQEQEDKMWRQEEKIREQEEK 585 Query: 189 APREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEV--DSALVVES 246 R+ +K E+E + EE + KI +E ++ + E Sbjct: 586 VWRQEEKIREQEEKRQEQEEKMWKQEEKIREQEEKIQEQEEKIREQEEKIREQEEMTQEQ 645 Query: 247 EHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFLALDEQKVCSAQ 306 E E+EE + E + EE + R +K + E+K+ + Sbjct: 646 EEKMGEQEEKMCEQEEKMQEQEETMWRQEEKIREQEKK----------IREQEEKIREQE 695 Query: 307 DVARDYSNPKWDETSLGFLEKQSDLEE 333 ++ ++ W++ EK + EE Sbjct: 696 EMMQEQEEKMWEQE-----EKMCEQEE 717 Score = 41.6 bits (96), Expect = 0.002 Identities = 78/421 (18%), Positives = 165/421 (39%), Gaps = 40/421 (9%) Query: 22 QELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYKCEEYKDIIDSVLRDELQSMEK 81 QE ++ E ++ R+ +EK + + ++++ EE + +R + + M + Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQ--EEMMWEKEEKMRRQEEMMWE 374 Query: 82 LAEKLRQAEE--------LRQYKALVHSQAK-----ELTQLREKLREGRDASRWLNKHLK 128 EK+R+ EE +R+ + +H Q K E Q EK+RE K Sbjct: 375 KEEKMRRQEEMMWEKEEKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAK--- 431 Query: 129 TLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEKVQESP 188 + ++ + Q + +REQ + R E +H+ +E++ +++++ + EK+ E Sbjct: 432 -MWRQEEKIREQEEKIREQEKKMWR-QEEKIHEQEKIREEEKRQEQEEMWRQEEKIHEQE 489 Query: 189 AP-REVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVVESE 247 R+ +K E+E EE + K+ +E ++ E E Sbjct: 490 EIWRQKEKMHEQEEKIRKQEEKVWRQEEKIREQEEKIREQEEKMWRQEEKIR-----EQE 544 Query: 248 HPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFLALDEQKVCSAQD 307 EEE+ Q EEE + + + R +E + E+K+ ++ Sbjct: 545 EMWREEEKM-----HEQEKIWEEEKRQEQEDKMWRQEEKIREQEEK-VWRQEEKIREQEE 598 Query: 308 VARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLT 367 ++ W + EK + EE ++ R +R ++ E+ QE + Sbjct: 599 KRQEQEEKMWKQE-----EKIREQEEKIQEQEEKIREQEEKIR-EQEEMTQEQEEKMGEQ 652 Query: 368 PSILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEEIEDQSPPCPRLSQELPEVKE 427 + + T++ E+K KI++ +E+I +Q +++ E +E Sbjct: 653 EEKMCEQEEKMQEQEETMWRQEEK--IREQEKKIREQEEKIREQEEMMQEQEEKMWEQEE 710 Query: 428 Q 428 + Sbjct: 711 K 711 >gi|150010604 kinesin family member 4B [Homo sapiens] Length = 1234 Score = 51.6 bits (122), Expect = 2e-06 Identities = 58/209 (27%), Positives = 96/209 (45%), Gaps = 35/209 (16%) Query: 19 EINQELRSQLAESNQQFRDLKEKFLITQATAYSLAN-QLKKYKCEEYKDIIDSVLRDELQ 77 EI EL+++L QQ ++ K +L++Q +A QL+K E+ + ++ S L+ + + Sbjct: 911 EIETELQAELVRMEQQHQE-KVLYLVSQLQESQMAEKQLEKSASEKEQQLV-STLQCQDE 968 Query: 78 SMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDASRWLNKHLK--TLLTPDD 135 +EK+ E Q ++L Q ++ ++KL + ASR KHL TLL+PD Sbjct: 969 ELEKMREVCEQNQQLLQENEII----------KQKLILLQVASR--QKHLPNDTLLSPDS 1016 Query: 136 -----PDKSQGQDLREQLAEGHRLAEHLV----HKLSPENDEDEDEDEDDKDEEVEKVQE 186 P K + ++E+ E E L H ++ D D D D D+ D+E K Sbjct: 1017 SFEYIPPKPKPSRVKEKFLEQSMDIEDLKYCSEHSVNEHEDGDGDGDSDEGDDEEWK--- 1073 Query: 187 SPAPREVQKTEEKEVPQDSLEECAVTCSN 215 P ++ K K + S C C N Sbjct: 1074 ---PTKLVKVSRKNIQGCS---CKGWCGN 1096 >gi|239745079 PREDICTED: Putative golgin subfamily A member 6-like protein 6 [Homo sapiens] Length = 724 Score = 51.2 bits (121), Expect = 3e-06 Identities = 52/268 (19%), Positives = 108/268 (40%), Gaps = 29/268 (10%) Query: 11 ERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYKCEEYKDIIDS 70 E ++ E QE +++ ++ R+ +EK + + ++ K E + I + Sbjct: 462 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEEKMWR-----QEEKIHEQEKIREE 516 Query: 71 VLRDELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKL----REGRDASRWLNKH 126 R E + M + EK+R+ EE+ + K +H Q +++ + EK+ + D + + Sbjct: 517 EKRQEQEEMWRQEEKIREQEEIWRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQ 576 Query: 127 LKTLLTPDDPDKSQGQDLREQ---LAEGHRLAEHLVHKLSP------ENDEDEDEDEDDK 177 + + ++ + Q + +REQ + E + + K+ E +E E E+ Sbjct: 577 EEKVWRQEEKIREQEEKIREQEEKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKM 636 Query: 178 DEEVEKVQESPAPREVQKTEEKEVPQDSL---------EECAVTCSNSHNPSNSNQPHRS 228 + EK++E +++++ EEK Q+ + E+ C + R Sbjct: 637 RRQEEKIREQ--EKKIREQEEKIREQEEMMQEQEEKMWEQEEKMCEQEEKMQEQEEKMRR 694 Query: 229 TKITFKEHEVDSALVVESEHPHDEEEEA 256 + E EV E H E EA Sbjct: 695 QEEKMWEQEVRLRQQEEKMQEHQEHLEA 722 Score = 45.1 bits (105), Expect = 2e-04 Identities = 59/331 (17%), Positives = 133/331 (40%), Gaps = 44/331 (13%) Query: 22 QELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKK-----YKCEEYKDIIDSVLRDEL 76 QE ++ E ++ R+ +EK + + ++++ ++ EE + ++ ++ Sbjct: 378 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRQEEMMWEKE 437 Query: 77 QSMEKLAEKL------RQAEELRQYKALVHSQAKELTQLREKLREGRDASRWLNKHLKTL 130 + + +L EK+ R+ EE RQ + + Q K R+ ++A W Sbjct: 438 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEK---------RQEQEAKMW-------- 480 Query: 131 LTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEKVQESPAP 190 ++ + Q + +REQ + R E +H+ +E++ +++++ + EK++E Sbjct: 481 -RQEEKIREQEEKIREQEEKMWR-QEEKIHEQEKIREEEKRQEQEEMWRQEEKIREQEEI 538 Query: 191 -REVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHEV--DSALVVESE 247 R+ +K E+E EE + + K+ +E ++ + E E Sbjct: 539 WRQKEKIHEQEEKIRKQEEKMWRQEEKMHDQEEKIREQEEKVWRQEEKIREQEEKIREQE 598 Query: 248 HPHDEEEEALNIPPENQNDHEE-----EEGKAPVPPRHHDKSNSYRHREVSFLALDEQKV 302 E+EE E + EE EE + + R +E + E+K+ Sbjct: 599 EKIREQEEMTQEQEEKMGEQEEKMCEQEEKMQEQEEKMRRQEEKIREQEKK-IREQEEKI 657 Query: 303 CSAQDVARDYSNPKWDETSLGFLEKQSDLEE 333 +++ ++ W++ EK + EE Sbjct: 658 REQEEMMQEQEEKMWEQE-----EKMCEQEE 683 >gi|239756241 PREDICTED: golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 899 Score = 49.3 bits (116), Expect = 1e-05 Identities = 69/342 (20%), Positives = 138/342 (40%), Gaps = 46/342 (13%) Query: 21 NQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLK--KYKCEEYKDIIDSVLRDELQS 78 N+EL+ + AE L+EK + ++ + +K K K E K ++ V + LQ Sbjct: 220 NEELKKKNAE-------LQEKLPLAESEKSEIQLNVKELKRKLERAKFLLPQVQTNTLQE 272 Query: 79 MEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREG----RDASRWLNKHLKTLLTPD 134 E RQ EELR+ + + Q +++ + E+LRE R+ + + K L + Sbjct: 273 -----EMWRQEEELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQEKRLREQE 327 Query: 135 DPDKSQGQDLREQ--LAEGHRLAEHLVHKLSPENDEDEDEDED---------DKDEEVEK 183 + Q ++LREQ L E + K+ + ++ +++E ++++++ + Sbjct: 328 KELREQEKELREQKELREQEEQMQEQEEKMWEQEEKMREQEEKMWRQEERLWEQEKQMRE 387 Query: 184 VQESPAPRE---------VQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFK 234 ++ +E +++ EE+ Q+ + E + R + + Sbjct: 388 QEQKMRDQEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQEKKTRDQEEKMQ 447 Query: 235 EHE---VDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHRE 291 E E + E E E+EE + EN + EE+E + P +K E Sbjct: 448 EEERIREREKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEKL-----WE 502 Query: 292 VSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEE 333 + E+K+ ++ RD E + EK + E+ Sbjct: 503 QEKMQEQEEKIWEQEEKIRDQEEMWGQEKKMWRQEKMREQED 544 Score = 48.5 bits (114), Expect = 2e-05 Identities = 56/307 (18%), Positives = 131/307 (42%), Gaps = 28/307 (9%) Query: 27 QLAESNQQFRDLKEKFLITQATAYSLANQLKKYKCEEYKDIIDSVLRDELQSMEKLAEKL 86 +L E ++ R +EK + ++++ + + ++ + LR++ + + + ++L Sbjct: 280 ELREQEKKIRKQEEKMWRQEERLREQEGKMREQEEKMWRQ--EKRLREQEKELREQEKEL 337 Query: 87 RQAEELRQYKALVHSQAKELTQLREKLREGRDASRWLNKHLKTLLTPDDPDKSQGQDLRE 146 R+ +ELR+ + + Q +++ + EK+RE ++ W + + L + + Q Q +R+ Sbjct: 338 REQKELREQEEQMQEQEEKMWEQEEKMRE-QEEKMW--RQEERLWEQEKQMREQEQKMRD 394 Query: 147 QLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEKVQESPAPREVQKTEEKEVPQDSL 206 Q E L K ++++ ++ +K E +K+QE ++ + EEK ++ + Sbjct: 395 QEERMWEQDERLREKEERMREQEKMWEQVEKMREEKKMQEQ--EKKTRDQEEKMQEEERI 452 Query: 207 EECAVTCSNSHNPSNSNQPHRSTKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQND 266 E + R + T +E E E+ +E+E PE + Sbjct: 453 RE-------------REKKMREEEETMREQEEKMQKQEENMWEQEEKEWQQQRLPEQKEK 499 Query: 267 HEEEEGKAPVPPRHHDKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLE 326 E+E + ++ R +E + ++K Q+ R+ + W++ E Sbjct: 500 LWEQEKMQEQEEKIWEQEEKIRDQEEMW---GQEKKMWRQEKMREQEDQMWEQE-----E 551 Query: 327 KQSDLEE 333 K D E+ Sbjct: 552 KMRDQEQ 558 Score = 37.7 bits (86), Expect = 0.033 Identities = 52/278 (18%), Positives = 113/278 (40%), Gaps = 30/278 (10%) Query: 22 QELRSQLAESNQQFRDLKEKFLI--------TQATAYSLANQLKKYKCEEYKDIIDSVLR 73 +E Q+ E ++ RD ++K TQ +Q +K + EE + +R Sbjct: 540 REQEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMR 599 Query: 74 DELQSMEKLAEKLRQAEE-LRQYKALVHSQAKELTQLREKLREG------RDASRWLNKH 126 +E + M + EK+++ EE +++ + + Q +++ + EK+ E ++ W + Sbjct: 600 EEEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQR 659 Query: 127 L---KTLLTPDDPDKSQG--QDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDD----- 176 L K L + + Q Q+ E++ E ++ + + D+++ +E+ Sbjct: 660 LPEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKKTWDQEKMREEESMRERE 719 Query: 177 ----KDEEVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKIT 232 ++EE+ + QE + +K +E+E EE + P + K+ Sbjct: 720 KKMREEEEMMREQEEKMQEQEEKMQEQEEEMWEQEE-KMWEQEEKMWEQQRLPEQKEKLW 778 Query: 233 FKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEE 270 E + + E E ++EE + E EE+ Sbjct: 779 EHEKMQEQEKIWEQEEKMRDQEEKMRGQEEKMRGQEEK 816 Score = 35.4 bits (80), Expect = 0.16 Identities = 54/330 (16%), Positives = 127/330 (38%), Gaps = 14/330 (4%) Query: 12 RAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYKCEEYKDIIDSV 71 R E + E ++ R Q E Q+ ++E+ + ++ Q +K + +E Sbjct: 427 REEKKMQEQEKKTRDQ-EEKMQEEERIREREKKMREEEETMREQEEKMQKQEENMWEQEE 485 Query: 72 LRDELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDASRWLNKHLKTLL 131 + Q + + EKL + E++++ + + Q +++ E G++ W + ++ Sbjct: 486 KEWQQQRLPEQKEKLWEQEKMQEQEEKIWEQEEKIRDQEEMW--GQEKKMWRQEKMRE-- 541 Query: 132 TPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEKVQESPAPR 191 +D Q + +R+Q + E + K + + D++E ++EE + +E Sbjct: 542 -QEDQMWEQEEKMRDQEQKMWDQEERMEKKTQEQEKKTWDQEEKMREEERMREREKKMRE 600 Query: 192 EVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEH---EVDSALVVESEH 248 E + E+E EE + K+ +E E + + + Sbjct: 601 EEEMMREQEEKMQEQEEKMQEQEEKMWEQEEKMQEQEEKMWEQEEKMWEQEEKMWEQQRL 660 Query: 249 PHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFLALDEQKVCSAQDV 308 P +E+ + + Q +E+E K + K+ + D++K+ + + Sbjct: 661 PEQKEKLWEHEKMQEQEKMQEQEEKIWEQEKMEKKTQEQEKK-----TWDQEKMREEESM 715 Query: 309 ARDYSNPKWDETSLGFLEKQSDLEEVKGQE 338 + +E + E++ +E K QE Sbjct: 716 REREKKMREEEEMMREQEEKMQEQEEKMQE 745 >gi|116686122 kinesin family member 4 [Homo sapiens] Length = 1232 Score = 48.9 bits (115), Expect = 1e-05 Identities = 51/202 (25%), Positives = 90/202 (44%), Gaps = 23/202 (11%) Query: 19 EINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYKCEEYKDIIDSVLRDELQS 78 EI EL+++L QQ ++ K +L++Q +A + + E + + S L+ + + Sbjct: 911 EIETELQAELVRMEQQHQE-KVLYLLSQLQQSQMAEKQLEESVSEKEQQLLSTLKCQDEE 969 Query: 79 MEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDASRWLNKHLKTLLTPDD--- 135 +EK+ E Q ++L + ++ ++KL + ASR + TLL+PD Sbjct: 970 LEKMREVCEQNQQLLRENEII----------KQKLTLLQVASRQKHLPKDTLLSPDSSFE 1019 Query: 136 --PDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEKVQESPAPREV 193 P K + ++E+ E E L K E+ +E ED D D+E + E P ++ Sbjct: 1020 YVPPKPKPSRVKEKFLEQSMDIEDL--KYCSEHSVNEHEDGDGDDDEGD--DEEWKPTKL 1075 Query: 194 QKTEEKEVPQDSLEECAVTCSN 215 K K + S C C N Sbjct: 1076 VKVSRKNIQGCS---CKGWCGN 1094 Score = 32.7 bits (73), Expect = 1.1 Identities = 45/234 (19%), Positives = 88/234 (37%), Gaps = 49/234 (20%) Query: 11 ERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYKCEEYKDIIDS 70 E E + ++NQE+R + Q R +KE A + +++K ++ K++I Sbjct: 627 ESTERTVSKLNQEIRMMKNQRVQLMRQMKED-----------AEKFRQWKQKKDKEVIQL 675 Query: 71 VLRD-----ELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRD------- 118 RD EL +E+ +K Q+ LR+ + K L +K RE D Sbjct: 676 KERDRKRQYELLKLERNFQK--QSNVLRRKTEEAAAANKRLKDALQKQREVADKRKETQS 733 Query: 119 ---------ASRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDED 169 WL ++ +++ ++ + L ++ +A+ K S EN Sbjct: 734 RGMEGTAARVKNWLGNEIEVMVSTEEAKRHLNDLLEDRKILAQDVAQLKEKKESGENPPP 793 Query: 170 E---------------DEDEDDKDEEVEKVQESPAPREVQKTEEKEVPQDSLEE 208 + E ED +++E ++ R Q + ++ D+ E Sbjct: 794 KLRRRTFSLTEVRGQVSESEDSITKQIESLETEMEFRSAQIADLQQKLLDAESE 847 >gi|148839339 nexilin (F actin binding protein) [Homo sapiens] Length = 675 Score = 48.9 bits (115), Expect = 1e-05 Identities = 54/291 (18%), Positives = 117/291 (40%), Gaps = 38/291 (13%) Query: 3 VSADPLSSERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYKCE 62 +S + + +R E + +E R ++ E + F + + ++ + + YK Sbjct: 312 LSFEEMERQRREDEKRKAEEEARRRIEEEKKAFAEARRNMVVDDDSP-------EMYKTI 364 Query: 63 EYKDIIDSVLRDELQSM--EKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDAS 120 + + L + + +K+ E+ R+ EE R++K + Q E QLR+++ E + + Sbjct: 365 SQEFLTPGKLEINFEELLKQKMEEEKRRTEEERKHKLEMEKQ--EFEQLRQEMGEEEEEN 422 Query: 121 RW--LNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPEN------------ 166 L++ + L+ Q ++L+ + + +L+E + K E Sbjct: 423 ETFGLSREYEELIKLKRSGSIQAKNLKSKFEKIGQLSEKEIQKKIEEERARRRAIDLEIK 482 Query: 167 --DEDEDEDEDDKDEEVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQ 224 + + +EDD D + E+P +V E + EE + Sbjct: 483 EREAENFHEEDDVDVRPARKSEAPFTHKVNMKARFEQMAKAREE---------EEQRRIE 533 Query: 225 PHRSTKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAP 275 + ++ F++ E+D+AL + + +EEEE + D E+ AP Sbjct: 534 EQKLLRMQFEQREIDAAL--QKKREEEEEEEGSIMNGSTAEDEEQTRSGAP 582 >gi|100816397 MYST histone acetyltransferase (monocytic leukemia) 4 [Homo sapiens] Length = 2073 Score = 48.1 bits (113), Expect = 2e-05 Identities = 56/255 (21%), Positives = 99/255 (38%), Gaps = 39/255 (15%) Query: 41 KFLITQATAYSLANQLKKYKCEEYKDIIDSVLR------DELQSMEKLAEKLRQAEELRQ 94 +F+I + L++ K C ++ LR E+ E ++AE L + Sbjct: 954 RFVIIRREKLILSHMEKLKTCSRANELDPDSLRWTPILISNAAVSEEEREAEKEAERLME 1013 Query: 95 YKALVHSQAKELTQLREKLREGRDASRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRL 154 + + +E+ R R+ + NK+L + P+ R QL E Sbjct: 1014 QASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHS------PESRPVTGERGQLLE---- 1063 Query: 155 AEHLVHKLSPENDEDEDEDEDDKDEEVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCS 214 LS E+ E+E+E+ED+++EE E+ +E E ++ EE+E +T Sbjct: 1064 -------LSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPRLTKP 1116 Query: 215 NSHNPSNSNQPHRSTKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHE------ 268 S K K ++S++ E+ E E LN P +N ++ Sbjct: 1117 QSVAIKRKRPFVLKKKRGRKRRRINSSVTTET---ISETTEVLNEPFDNSDEERPMPQLE 1173 Query: 269 -------EEEGKAPV 276 EE+G+ PV Sbjct: 1174 PTCEIEVEEDGRKPV 1188 Score = 42.4 bits (98), Expect = 0.001 Identities = 82/432 (18%), Positives = 159/432 (36%), Gaps = 61/432 (14%) Query: 135 DPDKSQGQDLRE-----QLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEKVQESPA 189 DPD ++ Q+ E + + RL +H +E+E+++E +E+ + E + Sbjct: 1381 DPDGAKSQEKEEPEISTEKEDSARLDDH--------EEEEEEDEEPSHNEDHDADDEDDS 1432 Query: 190 PREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSN-QPHRSTKITFKEHEVDSALVVESEH 248 E + E++E+P++S +E N + N QP S + VD SE Sbjct: 1433 HMESAEVEKEELPRESFKE---VLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSE- 1488 Query: 249 PHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFLALDEQKVCSAQDV 308 P + + +P ++ E+ + + ++ + + +D + V + Q + Sbjct: 1489 PKELAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSL 1548 Query: 309 ARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLSRGPLRVDKHEIPQESLDGCCLTP 368 ++ S +Q D + + A R + R D+ +LD C + Sbjct: 1549 TQESS-------------EQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSD 1595 Query: 369 SILPDLTPSYHPYWSTLYSFEDKQVSLALVDKIKKDQEEIE-DQSPPCPRLSQELPEVKE 427 P + HP S + V+ V ++ +I DQS Q + Sbjct: 1596 HSSPVSSVHSHPGQSV------RSVNSPSVPALENSYAQISPDQSAISVPSLQNMETSPM 1649 Query: 428 QEVPEDSVNEVYLTPSVHHDVSDCH---------QPYSSTL-------SSLEDQLACSAL 471 +VP S + + S D+ Y ST+ S ++ + S L Sbjct: 1650 MDVPSVSDHSQQVVDSGFSDLGSIESTTENYENPSSYDSTMGGSICGNGSSQNSCSYSNL 1709 Query: 472 DVASPTEAACPQGTWSGDLSHHQSEVQVSQAQLEPSTLVPSCLRLQLDQGFHCGNGLAQR 531 +S T+++C ++S S +Q + P+ V S +++ LAQ Sbjct: 1710 TSSSLTQSSCAVTQQMSNISGSCSMLQQTSISSPPTCSVKSPQGCVVERPPSSSQQLAQ- 1768 Query: 532 GLSSTTCSFSAN 543 CS +AN Sbjct: 1769 ------CSMAAN 1774 Score = 39.3 bits (90), Expect = 0.011 Identities = 70/357 (19%), Positives = 129/357 (36%), Gaps = 56/357 (15%) Query: 162 LSPENDEDEDEDEDDKDEEVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSN 221 + PE +E+E+E+E++++EE E+ +E V+K + Q+ E P Sbjct: 1348 IKPEEEEEEEEEEEEEEEE-EEGEEEEGGGNVEKDPDGAKSQEKEE-----------PEI 1395 Query: 222 SNQPHRSTKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHH 281 S + S ++ E E + + E H+E+ +A ++++D E + Sbjct: 1396 STEKEDSARLDDHEEEEEE----DEEPSHNEDHDA-----DDEDDSHMESAEVEKEELPR 1446 Query: 282 DKSNSYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVA 341 + + +FL L+ Q S +V D + E D E V + Sbjct: 1447 ESFKEVLENQETFLDLNVQPGHSNPEVLMDCGVDLTASCNSEPKELAGDPEAVPESDEEP 1506 Query: 342 PRLSRGPLRVDKH--EIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLALVD 399 P + + K+ E+ E +G P+ + E ++ V Sbjct: 1507 PPGEQAQKQDQKNSKEVDTEFKEG---NPA-----------------TMEIDSETVQAVQ 1546 Query: 400 KIKKDQEEIEDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQ-PYSST 458 + ++ E +D C + ++ + S P + + DC Q +SS Sbjct: 1547 SLTQESSEQDDTFQDCAETQEACRSLQNYTRADQS-------PQIATTLDDCQQSDHSSP 1599 Query: 459 LSSLEDQLACSALDVASPTEAACPQGTWSGDLSHHQSEVQVSQAQ---LEPSTLVPS 512 +SS+ S V SP+ A +S QS + V Q P VPS Sbjct: 1600 VSSVHSHPGQSVRSVNSPSVPALENS--YAQISPDQSAISVPSLQNMETSPMMDVPS 1654 Score = 36.2 bits (82), Expect = 0.095 Identities = 32/140 (22%), Positives = 59/140 (42%), Gaps = 23/140 (16%) Query: 133 PDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEK------VQE 186 P P+ S G+ + L K E +E+E+E+E++++EE E+ V++ Sbjct: 1332 PVSPNTSPGEKPEDDLI-----------KPEEEEEEEEEEEEEEEEEEGEEEEGGGNVEK 1380 Query: 187 SPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKEHE--VDSALVV 244 P + Q+ EE E+ + + + + H E + ++SA V Sbjct: 1381 DPDGAKSQEKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAEVE 1440 Query: 245 ESEHPHDEEEEALNIPPENQ 264 + E P + +E L ENQ Sbjct: 1441 KEELPRESFKEVL----ENQ 1456 Score = 35.8 bits (81), Expect = 0.12 Identities = 90/422 (21%), Positives = 138/422 (32%), Gaps = 88/422 (20%) Query: 117 RDASRWL-NKHLKTLL---------TPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPEN 166 R S+W NK KT TP +PD+ + +++ +EG K SP Sbjct: 1254 RGLSKWRQNKERKTGFKLNLYTPPETPMEPDEQVTVEEQKETSEG---------KTSPSP 1304 Query: 167 DEDEDEDEDDKDEEVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPH 226 E EEV++ E+ P+E + EE P S N S +P Sbjct: 1305 IRIE--------EEVKETGEALLPQEENRREETCAPV------------SPNTSPGEKPE 1344 Query: 227 RSTKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHD-KSN 285 D + E E +EEEE E + + EEEEG V KS Sbjct: 1345 ------------DDLIKPEEEEEEEEEEE----EEEEEEEGEEEEGGGNVEKDPDGAKSQ 1388 Query: 286 SYRHREVSFLALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEEVKGQETVAPRLS 345 E+S D ++ ++ + P +E E S +E + Sbjct: 1389 EKEEPEISTEKEDSARLDDHEEEEEEDEEPSHNEDHDADDEDDSHMESAE---------- 1438 Query: 346 RGPLRVDKHEIPQESLDGCCLTPSILPDLTPSYHPYWSTLYSFEDKQVSLAL-----VDK 400 V+K E+P+ES DL + P S D V L + Sbjct: 1439 -----VEKEELPRESFKEVLENQETFLDL--NVQPGHSNPEVLMDCGVDLTASCNSEPKE 1491 Query: 401 IKKDQEEI--EDQSPPCPRLSQELPEVKEQEVPEDSVNEVYLTPSVHHDVSDCHQPYSST 458 + D E + D+ PP +Q+ + +EV + T + + Q + Sbjct: 1492 LAGDPEAVPESDEEPPPGEQAQKQDQKNSKEVDTEFKEGNPATMEIDSETVQAVQSLTQE 1551 Query: 459 LSSLED--------QLACSALDVASPTEAACPQGTWSGDLSHHQSEVQVSQAQLEPSTLV 510 S +D Q AC +L + + + T D VS P V Sbjct: 1552 SSEQDDTFQDCAETQEACRSLQNYTRADQSPQIATTLDDCQQSDHSSPVSSVHSHPGQSV 1611 Query: 511 PS 512 S Sbjct: 1612 RS 1613 Score = 35.0 bits (79), Expect = 0.21 Identities = 27/114 (23%), Positives = 52/114 (45%), Gaps = 6/114 (5%) Query: 172 EDEDDKDEEVEKVQESPAPREVQKTEEKEVPQDSLEECAVTCSNS---HNPSN---SNQP 225 E+E + ++E E++ E + E ++ E +S + A S + H+P + + + Sbjct: 999 EEEREAEKEAERLMEQASCWEKEEQEILSTRANSRQSPAKVQSKNKYLHSPESRPVTGER 1058 Query: 226 HRSTKITFKEHEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPR 279 + +++ + E + E E +EEEE E + + EEEE PPR Sbjct: 1059 GQLLELSKESSEEEEEEEDEEEEEEEEEEEEDEEEEEEEEEEEEEENIQSSPPR 1112 >gi|222446603 golgi autoantigen, golgin subfamily a-like [Homo sapiens] Length = 668 Score = 47.8 bits (112), Expect = 3e-05 Identities = 38/196 (19%), Positives = 88/196 (44%), Gaps = 11/196 (5%) Query: 11 ERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKYKCEEYKDIIDS 70 E ++ E QE +++ ++ R+ +EK + + ++ K E + I + Sbjct: 401 EEEKIREQEKRQEQEAKMWRQEEKIREQEEKIREQEKKMWR-----QEEKIHEQEKIREE 455 Query: 71 VLRDELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREG---RDASRWLNKHL 127 R E + M + EK+R+ EE+ + K +H Q K Q + R+ D + + Sbjct: 456 EKRQEQEEMWRQEEKIREQEEIWRQKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQE 515 Query: 128 KTLLTPDDPDKSQGQDLREQ---LAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEKV 184 + + ++ + Q + +REQ + E + + K+ + ++ +++++ + EE + Sbjct: 516 EKMWRQEEKIREQEEKIREQEEKIREQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIRE 575 Query: 185 QESPAPREVQKTEEKE 200 QE + +K E+E Sbjct: 576 QEEKIREQKEKIREQE 591 Score = 39.7 bits (91), Expect = 0.009 Identities = 59/338 (17%), Positives = 135/338 (39%), Gaps = 53/338 (15%) Query: 22 QELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKK-----YKCEEYKDIIDSV----- 71 QE ++ E ++ R+ +EK + + ++++ ++ EE ++ + Sbjct: 317 QEQEEKIREQEEKIREQEEKMRRQEEMMWEKEEKMRRQEEMMWEKEEKMRRLEEMMWEKE 376 Query: 72 -----LRDELQSMEKLAE---------KLRQAEELRQYKALVHSQAKELTQLREKLREGR 117 L +++ EK+ E K+R+ E+ ++ +A + Q +++ + EK+RE + Sbjct: 377 EKIRELEEKMHEQEKIREQEEKRQEEEKIREQEKRQEQEAKMWRQEEKIREQEEKIRE-Q 435 Query: 118 DASRWLNKHLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDK 177 + W + + +K + ++ R++ E R E + +++E + +K Sbjct: 436 EKKMWRQEE-----KIHEQEKIREEEKRQEQEEMWRQEEKI-------REQEEIWRQKEK 483 Query: 178 DEEVEKV--QESPAPREVQKTEEKEVPQDSLEECAVTCSNSHNPSNSNQPHRSTKITFKE 235 E EK+ QE R+ +K ++E EE + KI +E Sbjct: 484 MHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKIREQE 543 Query: 236 HEVDSALVVESEHPHDEEEEALNIPPENQNDHEEEEGKAPVPPRHHDKSNSYRHREVSFL 295 ++ E E E+EE + E + +EE + ++ R +E Sbjct: 544 E-----MMQEQEEKMGEQEEKMQ---EQEKMRRQEEKIREQEEKIREQKEKIREQEEKIW 595 Query: 296 ALDEQKVCSAQDVARDYSNPKWDETSLGFLEKQSDLEE 333 E+K+ +++ ++ W++ EK + EE Sbjct: 596 E-QEEKIREQEEMMQEQEEKMWEQE-----EKMCEQEE 627 Score = 38.5 bits (88), Expect = 0.019 Identities = 39/205 (19%), Positives = 93/205 (45%), Gaps = 36/205 (17%) Query: 11 ERAEMNILEINQELRSQLAESNQQFRDLKEKFLITQATAYSLANQLKKY--KCEEYKDII 68 ++ +M+ E ++ ++ ++ D +EK + + ++++ K E ++ I Sbjct: 480 QKEKMHEQEKIRKQEEKVWRQEEKMHDQEEKIREQEEKMWRQEEKIREQEEKIREQEEKI 539 Query: 69 ---DSVLRDELQSMEKLAEKLRQAEELRQYKALVHSQAKELTQLREKLREGRDASRWLNK 125 + +++++ + M + EK+++ E++R+ + + Q +++ + +EK+RE ++ W Sbjct: 540 REQEEMMQEQEEKMGEQEEKMQEQEKMRRQEEKIREQEEKIREQKEKIRE-QEEKIW--- 595 Query: 126 HLKTLLTPDDPDKSQGQDLREQLAEGHRLAEHLVHKLSPENDEDEDEDEDDKDEEVEKVQ 185 Q + +REQ ++ E +E E E+ E+ EK+Q Sbjct: 596 -------------EQEEKIREQ------------EEMMQEQEEKMWEQEEKMCEQEEKMQ 630 Query: 186 ESPAP--REVQKTEEKEVPQDSLEE 208 E R+ +K E+EV EE Sbjct: 631 EQEEKMRRQEEKMWEQEVRLRQQEE 655 Database: hs.faa Posted date: Aug 4, 2009 4:42 PM Number of letters in database: 18,247,518 Number of sequences in database: 37,866 Lambda K H 0.310 0.127 0.363 Gapped Lambda K H 0.267 0.0410 0.140 Matrix: BLOSUM62 Gap Penalties: Existence: 11, Extension: 1 Number of Hits to DB: 26,829,177 Number of Sequences: 37866 Number of extensions: 1374434 Number of successful extensions: 17411 Number of sequences better than 10.0: 30 Number of HSP's better than 10.0 without gapping: 294 Number of HSP's successfully gapped in prelim test: 785 Number of HSP's that attempted gapping in prelim test: 9227 Number of HSP's gapped (non-prelim): 4349 length of query: 638 length of database: 18,247,518 effective HSP length: 109 effective length of query: 529 effective length of database: 14,120,124 effective search space: 7469545596 effective search space used: 7469545596 T: 11 A: 40 X1: 16 ( 7.1 bits) X2: 38 (14.6 bits) X3: 64 (24.7 bits) S1: 42 (21.7 bits) S2: 65 (29.6 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.