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Search of human proteins with 22027500
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|22027500 carbonic anhydrase VIII [Homo sapiens]
(290 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|22027500 carbonic anhydrase VIII [Homo sapiens] 603 e-173
gi|4885101 carbonic anhydrase VII isoform 1 [Homo sapiens] 214 5e-56
gi|4557395 carbonic anhydrase II [Homo sapiens] 200 1e-51
gi|192447434 carbonic anhydrase I [Homo sapiens] 196 3e-50
gi|192447432 carbonic anhydrase I [Homo sapiens] 196 3e-50
gi|192447430 carbonic anhydrase I [Homo sapiens] 196 3e-50
gi|4502517 carbonic anhydrase I [Homo sapiens] 196 3e-50
gi|38348436 carbonic anhydrase XIII [Homo sapiens] 186 2e-47
gi|6005723 carbonic anhydrase VB, mitochondrial precursor [Homo ... 184 8e-47
gi|62240989 carbonic anhydrase VII isoform 2 [Homo sapiens] 180 1e-45
gi|4885099 carbonic anhydrase III [Homo sapiens] 179 3e-45
gi|4502521 carbonic anhydrase VA, mitochondrial precursor [Homo ... 178 6e-45
gi|169636420 carbonic anhydrase IX precursor [Homo sapiens] 155 5e-38
gi|45935383 carbonic anhydrase XII isoform 2 precursor [Homo sap... 142 3e-34
gi|4502515 carbonic anhydrase XII isoform 1 precursor [Homo sapi... 142 3e-34
gi|6912284 carbonic anhydrase XIV precursor [Homo sapiens] 136 2e-32
gi|130979954 carbonic anhydrase X [Homo sapiens] 134 7e-32
gi|130979679 carbonic anhydrase X [Homo sapiens] 134 7e-32
gi|9910366 carbonic anhydrase X [Homo sapiens] 134 7e-32
gi|70167127 carbonic anhydrase VI precursor [Homo sapiens] 133 2e-31
gi|194097398 protein tyrosine phosphatase, receptor type, G prec... 126 3e-29
gi|9951923 carbonic anhydrase XI precursor [Homo sapiens] 121 8e-28
gi|4502519 carbonic anhydrase IV precursor [Homo sapiens] 109 2e-24
gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1 p... 108 4e-24
gi|109134336 SH3-domain binding protein 5 (BTK-associated) isofo... 34 0.17
gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo ... 33 0.29
gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo ... 33 0.29
gi|239750077 PREDICTED: hypothetical protein [Homo sapiens] 32 0.65
gi|31543392 peroxisome proliferator-activated receptor gamma, co... 32 0.65
gi|239757628 PREDICTED: similar to hCG1646661 [Homo sapiens] 32 0.85
>gi|22027500 carbonic anhydrase VIII [Homo sapiens]
Length = 290
Score = 603 bits (1554), Expect = e-173
Identities = 290/290 (100%), Positives = 290/290 (100%)
Query: 1 MADLSFIEDTVAFPEKEEDEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREAR 60
MADLSFIEDTVAFPEKEEDEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREAR
Sbjct: 1 MADLSFIEDTVAFPEKEEDEEEEEEGVEWGYEEGVEWGLVFPDANGEYQSPINLNSREAR 60
Query: 61 YDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWG 120
YDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWG
Sbjct: 61 YDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWG 120
Query: 121 RENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLK 180
RENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLK
Sbjct: 121 RENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLK 180
Query: 181 AVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPL 240
AVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPL
Sbjct: 181 AVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPL 240
Query: 241 TISQLQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ 290
TISQLQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ
Sbjct: 241 TISQLQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ 290
>gi|4885101 carbonic anhydrase VII isoform 1 [Homo sapiens]
Length = 264
Score = 214 bits (546), Expect = 5e-56
Identities = 110/268 (41%), Positives = 161/268 (60%), Gaps = 17/268 (6%)
Query: 29 WGYEEG---VEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTND 85
WGY + W ++P A G+ QSPIN+ S +A Y PSL + LS Y C +TN+
Sbjct: 7 WGYGQDDGPSHWHKLYPIAQGDRQSPINIISSQAVYSPSLQPLELS--YEACMSLSITNN 64
Query: 86 GHTIQVILKS---KSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHL 142
GH++QV ++V++GGPL + L + FHWG+++ GSEHTV+ K+FP ELHL
Sbjct: 65 GHSVQVDFNDSDDRTVVTGGPLEG--PYRLKQFHFHWGKKHDVGSEHTVDGKSFPSELHL 122
Query: 143 IHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFN 202
+HWN+ + + EA P G+A++ +F++ G EH + +T+ L +++KG CFN
Sbjct: 123 VHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQFSCFN 182
Query: 203 PNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAEL 262
P LL P R YW Y GSLT PP SE VTWI+ R P+ IS+ Q+ +FR L + E
Sbjct: 183 PKCLL--PASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSEDDER 240
Query: 263 VEGCDGILGDNFRPTQPLSDRVIRAAFQ 290
+ + +NFRP QPL RV++A+F+
Sbjct: 241 IH-----MVNNFRPPQPLKGRVVKASFR 263
>gi|4557395 carbonic anhydrase II [Homo sapiens]
Length = 260
Score = 200 bits (508), Expect = 1e-51
Identities = 110/268 (41%), Positives = 162/268 (60%), Gaps = 18/268 (6%)
Query: 29 WGY--EEGVE-WGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTND 85
WGY G E W FP A GE QSP+++++ A+YDPSL LS +Y + N+
Sbjct: 5 WGYGKHNGPEHWHKDFPIAKGERQSPVDIDTHTAKYDPSLKP--LSVSYDQATSLRILNN 62
Query: 86 GHTIQVIL---KSKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHL 142
GH V + K+VL GGPL + L + FHWG + +GSEHTV+ K + ELHL
Sbjct: 63 GHAFNVEFDDSQDKAVLKGGPLDG--TYRLIQFHFHWGSLDGQGSEHTVDKKKYAAELHL 120
Query: 143 IHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFN 202
+HWN T +G +AV +P G+A++ +F+++G GL+ V ++L I+ KGKS F+
Sbjct: 121 VHWN-TKYGDFGKAVQQPDGLAVLGIFLKVGSAKPGLQKVVDVLDSIKTKGKSADFTNFD 179
Query: 203 PNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAEL 262
P LLP+ L DYW Y GSLT PP E VTWI+ + P+++S Q+ +FR+L + +G
Sbjct: 180 PRGLLPESL--DYWTYPGSLTTPPLLECVTWIVLKEPISVSSEQVLKFRKLNFNGEGEP- 236
Query: 263 VEGCDGILGDNFRPTQPLSDRVIRAAFQ 290
+ ++ DN+RP QPL +R I+A+F+
Sbjct: 237 ----EELMVDNWRPAQPLKNRQIKASFK 260
>gi|192447434 carbonic anhydrase I [Homo sapiens]
Length = 261
Score = 196 bits (497), Expect = 3e-50
Identities = 103/268 (38%), Positives = 159/268 (59%), Gaps = 17/268 (6%)
Query: 28 EWGYEEG---VEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTN 84
+WGY++ +W ++P ANG QSP+++ + E ++D SL + +S N + E+ N
Sbjct: 5 DWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAK--EIIN 62
Query: 85 DGHTIQVILK---SKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELH 141
GH+ V + ++SVL GGP + L++ FHWG N+ GSEHTV+ + ELH
Sbjct: 63 VGHSFHVNFEDNDNRSVLKGGPFSDS--YRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH 120
Query: 142 LIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCF 201
+ HWNS + S+ EA K G+A+I + +++G+ + L+ V + LQ I+ KGK F
Sbjct: 121 VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF 180
Query: 202 NPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAE 261
+P+TLLP L D+W Y GSLT PP E VTWI+ + +++S Q+ +FR L ++V+G
Sbjct: 181 DPSTLLPSSL--DFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDN 238
Query: 262 LVEGCDGILGDNFRPTQPLSDRVIRAAF 289
V + N RPTQPL R +RA+F
Sbjct: 239 AVP-----MQHNNRPTQPLKGRTVRASF 261
>gi|192447432 carbonic anhydrase I [Homo sapiens]
Length = 261
Score = 196 bits (497), Expect = 3e-50
Identities = 103/268 (38%), Positives = 159/268 (59%), Gaps = 17/268 (6%)
Query: 28 EWGYEEG---VEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTN 84
+WGY++ +W ++P ANG QSP+++ + E ++D SL + +S N + E+ N
Sbjct: 5 DWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAK--EIIN 62
Query: 85 DGHTIQVILK---SKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELH 141
GH+ V + ++SVL GGP + L++ FHWG N+ GSEHTV+ + ELH
Sbjct: 63 VGHSFHVNFEDNDNRSVLKGGPFSDS--YRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH 120
Query: 142 LIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCF 201
+ HWNS + S+ EA K G+A+I + +++G+ + L+ V + LQ I+ KGK F
Sbjct: 121 VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF 180
Query: 202 NPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAE 261
+P+TLLP L D+W Y GSLT PP E VTWI+ + +++S Q+ +FR L ++V+G
Sbjct: 181 DPSTLLPSSL--DFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDN 238
Query: 262 LVEGCDGILGDNFRPTQPLSDRVIRAAF 289
V + N RPTQPL R +RA+F
Sbjct: 239 AVP-----MQHNNRPTQPLKGRTVRASF 261
>gi|192447430 carbonic anhydrase I [Homo sapiens]
Length = 261
Score = 196 bits (497), Expect = 3e-50
Identities = 103/268 (38%), Positives = 159/268 (59%), Gaps = 17/268 (6%)
Query: 28 EWGYEEG---VEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTN 84
+WGY++ +W ++P ANG QSP+++ + E ++D SL + +S N + E+ N
Sbjct: 5 DWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAK--EIIN 62
Query: 85 DGHTIQVILK---SKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELH 141
GH+ V + ++SVL GGP + L++ FHWG N+ GSEHTV+ + ELH
Sbjct: 63 VGHSFHVNFEDNDNRSVLKGGPFSDS--YRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH 120
Query: 142 LIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCF 201
+ HWNS + S+ EA K G+A+I + +++G+ + L+ V + LQ I+ KGK F
Sbjct: 121 VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF 180
Query: 202 NPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAE 261
+P+TLLP L D+W Y GSLT PP E VTWI+ + +++S Q+ +FR L ++V+G
Sbjct: 181 DPSTLLPSSL--DFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDN 238
Query: 262 LVEGCDGILGDNFRPTQPLSDRVIRAAF 289
V + N RPTQPL R +RA+F
Sbjct: 239 AVP-----MQHNNRPTQPLKGRTVRASF 261
>gi|4502517 carbonic anhydrase I [Homo sapiens]
Length = 261
Score = 196 bits (497), Expect = 3e-50
Identities = 103/268 (38%), Positives = 159/268 (59%), Gaps = 17/268 (6%)
Query: 28 EWGYEEG---VEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTN 84
+WGY++ +W ++P ANG QSP+++ + E ++D SL + +S N + E+ N
Sbjct: 5 DWGYDDKNGPEQWSKLYPIANGNNQSPVDIKTSETKHDTSLKPISVSYNPATAK--EIIN 62
Query: 85 DGHTIQVILK---SKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELH 141
GH+ V + ++SVL GGP + L++ FHWG N+ GSEHTV+ + ELH
Sbjct: 63 VGHSFHVNFEDNDNRSVLKGGPFSDS--YRLFQFHFHWGSTNEHGSEHTVDGVKYSAELH 120
Query: 142 LIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCF 201
+ HWNS + S+ EA K G+A+I + +++G+ + L+ V + LQ I+ KGK F
Sbjct: 121 VAHWNSAKYSSLAEAASKADGLAVIGVLMKVGEANPKLQKVLDALQAIKTKGKRAPFTNF 180
Query: 202 NPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAE 261
+P+TLLP L D+W Y GSLT PP E VTWI+ + +++S Q+ +FR L ++V+G
Sbjct: 181 DPSTLLPSSL--DFWTYPGSLTHPPLYESVTWIICKESISVSSEQLAQFRSLLSNVEGDN 238
Query: 262 LVEGCDGILGDNFRPTQPLSDRVIRAAF 289
V + N RPTQPL R +RA+F
Sbjct: 239 AVP-----MQHNNRPTQPLKGRTVRASF 261
>gi|38348436 carbonic anhydrase XIII [Homo sapiens]
Length = 262
Score = 186 bits (472), Expect = 2e-47
Identities = 104/271 (38%), Positives = 152/271 (56%), Gaps = 21/271 (7%)
Query: 27 VEWGYEEG---VEWGLVFPDANGEYQSPINLNSREARYDPSL--LDVRLSPNYVVCRDCE 81
+ WGY E + W FP A+G+ QSPI + ++E +YD SL L ++ P+
Sbjct: 4 LSWGYREHNGPIHWKEFFPIADGDQQSPIEIKTKEVKYDSSLRPLSIKYDPSSAKI---- 59
Query: 82 VTNDGHTIQVIL---KSKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPM 138
++N GH+ V ++KSVL GGPL + L +V HWG + GSEH V+ ++
Sbjct: 60 ISNSGHSFNVDFDDTENKSVLRGGPLTGS--YRLRQVHLHWGSADDHGSEHIVDGVSYAA 117
Query: 139 ELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTI 198
ELH++HWNS + S EA +P G+A++ +F+QIG+ + L+ +T+ L I+ KGK
Sbjct: 118 ELHVVHWNSDKYPSFVEAAHEPDGLAVLGVFLQIGEPNSQLQKITDTLDSIKEKGKQTRF 177
Query: 199 PCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVK 258
F+ +LLP DYW Y GSLT+PP E VTWI+ + P+ IS Q+ +FR L +
Sbjct: 178 TNFDLLSLLPPSW--DYWTYPGSLTVPPLLESVTWIVLKQPINISSQQLAKFRSLLCTAE 235
Query: 259 GAELVEGCDGILGDNFRPTQPLSDRVIRAAF 289
G L N RP QPL R +RA+F
Sbjct: 236 GE-----AAAFLVSNHRPPQPLKGRKVRASF 261
>gi|6005723 carbonic anhydrase VB, mitochondrial precursor [Homo
sapiens]
Length = 317
Score = 184 bits (467), Expect = 8e-47
Identities = 99/257 (38%), Positives = 151/257 (58%), Gaps = 14/257 (5%)
Query: 37 WGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKS- 95
W V G+ QSPIN+ R++ YDP L + +S + C V N+G++ V +
Sbjct: 52 WESVDLVPGGDRQSPINIRWRDSVYDPGLKPLTISYDPATC--LHVWNNGYSFLVEFEDS 109
Query: 96 --KSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSI 153
KSV+ GGPL H + L + FHWG + GSEHTV+ K FP ELHL+HWN+ F +
Sbjct: 110 TDKSVIKGGPLE--HNYRLKQFHFHWGAIDAWGSEHTVDSKCFPAELHLVHWNAVRFENF 167
Query: 154 DEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLR 213
++A + +G+A+I +F+++GK H L+ + + L I++K F+P+ L+ P
Sbjct: 168 EDAALEENGLAVIGVFLKLGKHHKELQKLVDTLPSIKHKDALVEFGSFDPSCLM--PTCP 225
Query: 214 DYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDN 273
DYW Y GSLT PP SE VTWI+ + P+ + Q+E+FR L +G + + + DN
Sbjct: 226 DYWTYSGSLTTPPLSESVTWIIKKQPVEVDHDQLEQFRTLLFTSEGEK-----EKRMVDN 280
Query: 274 FRPTQPLSDRVIRAAFQ 290
FRP QPL +R +R++F+
Sbjct: 281 FRPLQPLMNRTVRSSFR 297
>gi|62240989 carbonic anhydrase VII isoform 2 [Homo sapiens]
Length = 208
Score = 180 bits (456), Expect = 1e-45
Identities = 88/212 (41%), Positives = 132/212 (62%), Gaps = 12/212 (5%)
Query: 82 VTNDGHTIQVILKS---KSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPM 138
+TN+GH++QV ++V++GGPL + L + FHWG+++ GSEHTV+ K+FP
Sbjct: 5 ITNNGHSVQVDFNDSDDRTVVTGGPLEG--PYRLKQFHFHWGKKHDVGSEHTVDGKSFPS 62
Query: 139 ELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTI 198
ELHL+HWN+ + + EA P G+A++ +F++ G EH + +T+ L +++KG
Sbjct: 63 ELHLVHWNAKKYSTFGEAASAPDGLAVVGVFLETGDEHPSMNRLTDALYMVRFKGTKAQF 122
Query: 199 PCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVK 258
CFNP LL P R YW Y GSLT PP SE VTWI+ R P+ IS+ Q+ +FR L +
Sbjct: 123 SCFNPKCLL--PASRHYWTYPGSLTTPPLSESVTWIVLREPICISERQMGKFRSLLFTSE 180
Query: 259 GAELVEGCDGILGDNFRPTQPLSDRVIRAAFQ 290
E + + +NFRP QPL RV++A+F+
Sbjct: 181 DDERIH-----MVNNFRPPQPLKGRVVKASFR 207
>gi|4885099 carbonic anhydrase III [Homo sapiens]
Length = 260
Score = 179 bits (453), Expect = 3e-45
Identities = 100/269 (37%), Positives = 155/269 (57%), Gaps = 18/269 (6%)
Query: 28 EWGY--EEGVE-WGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTN 84
EWGY G + W +FP+A GE QSP+ L++++ R+DPSL +S + + + N
Sbjct: 4 EWGYASHNGPDHWHELFPNAKGENQSPVELHTKDIRHDPSLQPWSVSYDGGSAKT--ILN 61
Query: 85 DGHTIQVILKS---KSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELH 141
+G T +V+ +S+L GGPLP + L + HWG + GSEHTV+ + ELH
Sbjct: 62 NGKTCRVVFDDTYDRSMLRGGPLPG--PYRLRQFHLHWGSSDDHGSEHTVDGVKYAAELH 119
Query: 142 LIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCF 201
L+HWN + + EA+ + GIA+I +F++IG E+ + + L I+ KGK F
Sbjct: 120 LVHWNPK-YNTFKEALKQRDGIAVIGIFLKIGHENGEFQIFLDALDKIKTKGKEAPFTKF 178
Query: 202 NPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAE 261
+P+ L P RDYW Y+GS T PPC E + W+L + P+T+S Q+ + R L + +
Sbjct: 179 DPSCLFP--ACRDYWTYQGSFTTPPCEECIVWLLLKEPMTVSSDQMAKLRSLLSSAENEP 236
Query: 262 LVEGCDGILGDNFRPTQPLSDRVIRAAFQ 290
V L N+RP QP+++RV+RA+F+
Sbjct: 237 PVP-----LVSNWRPPQPINNRVVRASFK 260
>gi|4502521 carbonic anhydrase VA, mitochondrial precursor [Homo
sapiens]
Length = 305
Score = 178 bits (451), Expect = 6e-45
Identities = 99/257 (38%), Positives = 148/257 (57%), Gaps = 14/257 (5%)
Query: 37 WGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILKSK 96
W + G QSPIN+ R++ YDP L +R+S C + N G+ QV
Sbjct: 52 WTVPVSVPGGTRQSPINIQWRDSVYDPQLKPLRVSYEAASC--LYIWNTGYLFQVEFDDA 109
Query: 97 ---SVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSI 153
S +SGGPL + + L + FHWG N+ GSEHTV+ A+P ELHL+HWNS + +
Sbjct: 110 TEASGISGGPLE--NHYRLKQFHFHWGAVNEGGSEHTVDGHAYPAELHLVHWNSVKYQNY 167
Query: 154 DEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLR 213
EAV +G+A+I +F+++G H L+ + +IL +I++K + F+P+TLL P
Sbjct: 168 KEAVVGENGLAVIGVFLKLGAHHQTLQRLVDILPEIKHKDARAAMRPFDPSTLL--PTCW 225
Query: 214 DYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDN 273
DYW Y GSLT PP +E VTWI+ + P+ ++ Q+ FR L G E + ++ +N
Sbjct: 226 DYWTYAGSLTTPPLTESVTWIIQKEPVEVAPSQLSAFRTLLFSALGEE-----EKMMVNN 280
Query: 274 FRPTQPLSDRVIRAAFQ 290
+RP QPL +R + A+FQ
Sbjct: 281 YRPLQPLMNRKVWASFQ 297
>gi|169636420 carbonic anhydrase IX precursor [Homo sapiens]
Length = 459
Score = 155 bits (391), Expect = 5e-38
Identities = 98/298 (32%), Positives = 155/298 (52%), Gaps = 26/298 (8%)
Query: 1 MADLSFIEDTVAFPEKEEDEEEEEEGVE---WGYEEGVEWGLVFPDANGEYQSPINLNSR 57
+ DL +E E + + ++EG + W Y W V P G +QSP+++ +
Sbjct: 110 LEDLPTVEAPGDPQEPQNNAHRDKEGDDQSHWRYGGDPPWPRVSPACAGRFQSPVDIRPQ 169
Query: 58 EARYDPSL-----LDVRLSPNYVVCRDCEVTNDGHTIQVILKSKSVLSGGPLPQGHEFEL 112
A + P+L L +L P + + N+GH++Q+ L ++ GP G E+
Sbjct: 170 LAAFCPALRPLELLGFQLPP----LPELRLRNNGHSVQLTLPPGLEMALGP---GREYRA 222
Query: 113 YEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQI 172
++ HWG + GSEHTV FP E+H++H ST F +DEA+G+P G+A++A F++
Sbjct: 223 LQLHLHWGAAGRPGSEHTVEGHRFPAEIHVVHL-STAFARVDEALGRPGGLAVLAAFLEE 281
Query: 173 G-KEHVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGV 231
G +E+ + + L++I +G +P + + LLP R Y+ YEGSLT PPC++GV
Sbjct: 282 GPEENSAYEQLLSRLEEIAEEGSETQVPGLDISALLPSDFSR-YFQYEGSLTTPPCAQGV 340
Query: 232 TWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIRAAF 289
W +F + +S Q+ H L D L NFR TQPL+ RVI A+F
Sbjct: 341 IWTVFNQTVMLSAKQL--------HTLSDTLWGPGDSRLQLNFRATQPLNGRVIEASF 390
>gi|45935383 carbonic anhydrase XII isoform 2 precursor [Homo
sapiens]
Length = 343
Score = 142 bits (358), Expect = 3e-34
Identities = 85/269 (31%), Positives = 138/269 (51%), Gaps = 13/269 (4%)
Query: 26 GVEWGY---EEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSP-NYVVCRDCE 81
G +W Y + W +P G QSPI+L+S +YD SL + N +
Sbjct: 29 GSKWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFL 88
Query: 82 VTNDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWGRENQ-RGSEHTVNFKAFPMEL 140
+TN+GH++++ L S + G + ++ HWG N GSEHTV+ + F EL
Sbjct: 89 LTNNGHSVKLNLPSDMHIQG----LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAEL 144
Query: 141 HLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPC 200
H++H+NS L+ A K G+A++A+ +++G + + LQ ++YKG+ +P
Sbjct: 145 HIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPG 204
Query: 201 FNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGA 260
FN LLP+ +Y+ Y GSLT PPC+ V W +FR P+ ISQ E+ L T +
Sbjct: 205 FNIEELLPE-RTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQ---EQLLALETALYCT 260
Query: 261 ELVEGCDGILGDNFRPTQPLSDRVIRAAF 289
+ + + +NFR Q +R++ +F
Sbjct: 261 HMDDPSPREMINNFRQVQKFDERLVYTSF 289
>gi|4502515 carbonic anhydrase XII isoform 1 precursor [Homo
sapiens]
Length = 354
Score = 142 bits (358), Expect = 3e-34
Identities = 85/269 (31%), Positives = 138/269 (51%), Gaps = 13/269 (4%)
Query: 26 GVEWGY---EEGVEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSP-NYVVCRDCE 81
G +W Y + W +P G QSPI+L+S +YD SL + N +
Sbjct: 29 GSKWTYFGPDGENSWSKKYPSCGGLLQSPIDLHSDILQYDASLTPLEFQGYNLSANKQFL 88
Query: 82 VTNDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWGRENQ-RGSEHTVNFKAFPMEL 140
+TN+GH++++ L S + G + ++ HWG N GSEHTV+ + F EL
Sbjct: 89 LTNNGHSVKLNLPSDMHIQG----LQSRYSATQLHLHWGNPNDPHGSEHTVSGQHFAAEL 144
Query: 141 HLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGKEHVGLKAVTEILQDIQYKGKSKTIPC 200
H++H+NS L+ A K G+A++A+ +++G + + LQ ++YKG+ +P
Sbjct: 145 HIVHYNSDLYPDASTASNKSEGLAVLAVLIEMGSFNPSYDKIFSHLQHVKYKGQEAFVPG 204
Query: 201 FNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGA 260
FN LLP+ +Y+ Y GSLT PPC+ V W +FR P+ ISQ E+ L T +
Sbjct: 205 FNIEELLPE-RTAEYYRYRGSLTTPPCNPTVLWTVFRNPVQISQ---EQLLALETALYCT 260
Query: 261 ELVEGCDGILGDNFRPTQPLSDRVIRAAF 289
+ + + +NFR Q +R++ +F
Sbjct: 261 HMDDPSPREMINNFRQVQKFDERLVYTSF 289
>gi|6912284 carbonic anhydrase XIV precursor [Homo sapiens]
Length = 337
Score = 136 bits (343), Expect = 2e-32
Identities = 83/272 (30%), Positives = 146/272 (53%), Gaps = 20/272 (7%)
Query: 26 GVEWGYE--EGVE-WGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPN---YVVCRD 79
G W YE G + W +P+ QSPI++ + +DP L L P+
Sbjct: 19 GQHWTYEGPHGQDHWPASYPECGNNAQSPIDIQTDSVTFDPDL--PALQPHGYDQPGTEP 76
Query: 80 CEVTNDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWGRENQRG-SEHTVNFKAFPM 138
++ N+GHT+Q+ L S L G P ++ ++ HWG++ G SEH +N +A
Sbjct: 77 LDLHNNGHTVQLSLPSTLYLGGLP----RKYVAAQLHLHWGQKGSPGGSEHQINSEATFA 132
Query: 139 ELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGK-EHVGLKAVTEILQDIQYKGKSKT 197
ELH++H++S + S+ EA +P G+A++ + +++G+ +++ + + L ++++K + +
Sbjct: 133 ELHIVHYDSDSYDSLSEAAERPQGLAVLGILIEVGETKNIAYEHILSHLHEVRHKDQKTS 192
Query: 198 IPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHV 257
+P FN LLP L Y+ Y GSLT PPC + V W +F SQ+ +E+ +L+ +
Sbjct: 193 VPPFNLRELLPKQ-LGQYFRYNGSLTTPPCYQSVLWTVF---YRRSQISMEQLEKLQGTL 248
Query: 258 KGAELVEGCDGILGDNFRPTQPLSDRVIRAAF 289
E E +L N+R QPL+ R++ A+F
Sbjct: 249 FSTE--EEPSKLLVQNYRALQPLNQRMVFASF 278
>gi|130979954 carbonic anhydrase X [Homo sapiens]
Length = 328
Score = 134 bits (338), Expect = 7e-32
Identities = 83/276 (30%), Positives = 141/276 (51%), Gaps = 28/276 (10%)
Query: 29 WGYEEGVE---------WGLVFPDAN----GEYQSPINLNSREARYDPSLLDVRLSPNYV 75
W Y+E V+ WGLV N G+ QSP+N+ + +DP L +R++
Sbjct: 33 WAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSHMIFDPFLTPLRINTGGR 92
Query: 76 VCRDCEVTNDGHTIQVILKSKSV--LSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNF 133
+ N G + + L + + +SGGP+ H E E+R H+G E+ +GSEH +N
Sbjct: 93 KVSGT-MYNTGRHVSLRLDKEHLVNISGGPMTYSHRLE--EIRLHFGSEDSQGSEHLLNG 149
Query: 134 KAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQI---GKEHVGLKAVTEILQDIQ 190
+AF E+ LIH+N L+ ++ EA P+G+ ++++F+++ + + + I
Sbjct: 150 QAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRIT 209
Query: 191 YKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEF 250
YK + + N L P+ + Y+GS+TIPPC E +WI+ P+ I+++Q+
Sbjct: 210 YKNDAYLLQGLNIEELYPE--TSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSL 267
Query: 251 RRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIR 286
R L + + + DNFRP QPL++R IR
Sbjct: 268 RLLSQNQPSQIFLS-----MSDNFRPVQPLNNRCIR 298
>gi|130979679 carbonic anhydrase X [Homo sapiens]
Length = 328
Score = 134 bits (338), Expect = 7e-32
Identities = 83/276 (30%), Positives = 141/276 (51%), Gaps = 28/276 (10%)
Query: 29 WGYEEGVE---------WGLVFPDAN----GEYQSPINLNSREARYDPSLLDVRLSPNYV 75
W Y+E V+ WGLV N G+ QSP+N+ + +DP L +R++
Sbjct: 33 WAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSHMIFDPFLTPLRINTGGR 92
Query: 76 VCRDCEVTNDGHTIQVILKSKSV--LSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNF 133
+ N G + + L + + +SGGP+ H E E+R H+G E+ +GSEH +N
Sbjct: 93 KVSGT-MYNTGRHVSLRLDKEHLVNISGGPMTYSHRLE--EIRLHFGSEDSQGSEHLLNG 149
Query: 134 KAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQI---GKEHVGLKAVTEILQDIQ 190
+AF E+ LIH+N L+ ++ EA P+G+ ++++F+++ + + + I
Sbjct: 150 QAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRIT 209
Query: 191 YKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEF 250
YK + + N L P+ + Y+GS+TIPPC E +WI+ P+ I+++Q+
Sbjct: 210 YKNDAYLLQGLNIEELYPE--TSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSL 267
Query: 251 RRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIR 286
R L + + + DNFRP QPL++R IR
Sbjct: 268 RLLSQNQPSQIFLS-----MSDNFRPVQPLNNRCIR 298
>gi|9910366 carbonic anhydrase X [Homo sapiens]
Length = 328
Score = 134 bits (338), Expect = 7e-32
Identities = 83/276 (30%), Positives = 141/276 (51%), Gaps = 28/276 (10%)
Query: 29 WGYEEGVE---------WGLVFPDAN----GEYQSPINLNSREARYDPSLLDVRLSPNYV 75
W Y+E V+ WGLV N G+ QSP+N+ + +DP L +R++
Sbjct: 33 WAYKEVVQGSFVPVPSFWGLVNSAWNLCSVGKRQSPVNIETSHMIFDPFLTPLRINTGGR 92
Query: 76 VCRDCEVTNDGHTIQVILKSKSV--LSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNF 133
+ N G + + L + + +SGGP+ H E E+R H+G E+ +GSEH +N
Sbjct: 93 KVSGT-MYNTGRHVSLRLDKEHLVNISGGPMTYSHRLE--EIRLHFGSEDSQGSEHLLNG 149
Query: 134 KAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQI---GKEHVGLKAVTEILQDIQ 190
+AF E+ LIH+N L+ ++ EA P+G+ ++++F+++ + + + I
Sbjct: 150 QAFSGEVQLIHYNHELYTNVTEAAKSPNGLVVVSIFIKVSDSSNPFLNRMLNRDTITRIT 209
Query: 191 YKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEF 250
YK + + N L P+ + Y+GS+TIPPC E +WI+ P+ I+++Q+
Sbjct: 210 YKNDAYLLQGLNIEELYPE--TSSFITYDGSMTIPPCYETASWIIMNKPVYITRMQMHSL 267
Query: 251 RRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIR 286
R L + + + DNFRP QPL++R IR
Sbjct: 268 RLLSQNQPSQIFLS-----MSDNFRPVQPLNNRCIR 298
>gi|70167127 carbonic anhydrase VI precursor [Homo sapiens]
Length = 308
Score = 133 bits (334), Expect = 2e-31
Identities = 82/270 (30%), Positives = 140/270 (51%), Gaps = 21/270 (7%)
Query: 28 EWGYEEGV----EWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVT 83
+W Y EG W +P G+ QSPINL + RY+PSL + ++ + +
Sbjct: 22 DWTYSEGALDEAHWPQHYPACGGQRQSPINLQRTKVRYNPSLKGLNMTGYETQAGEFPMV 81
Query: 84 NDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWGRENQR--GSEHTVNFKAFPMELH 141
N+GHT+Q+ L S ++ + G + ++ FHWG + GSEHTV+ +E+H
Sbjct: 82 NNGHTVQISLPSTMRMT---VADGTVYIAQQMHFHWGGASSEISGSEHTVDGIRHVIEIH 138
Query: 142 LIHWNSTLFGSIDEAVGKPHGIAIIALFVQIGK--EHVGLKAVTEILQDIQYKGKSKTIP 199
++H+NS + S D A P G+A++A FV++ E+ L +I+Y G+ T+
Sbjct: 139 IVHYNSK-YKSYDIAQDAPDGLAVLAAFVEVKNYPENTYYSNFISHLANIKYPGQRTTLT 197
Query: 200 CFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKG 259
+ +LP L+ Y+ Y GSLT PPC+E V W + + +S+ Q+ +
Sbjct: 198 GLDVQDMLPRN-LQHYYTYHGSLTTPPCTENVHWFVLADFVKLSRTQVWKLEN------- 249
Query: 260 AELVEGCDGILGDNFRPTQPLSDRVIRAAF 289
L++ + + +++R TQPL+ RV+ + F
Sbjct: 250 -SLLDHRNKTIHNDYRRTQPLNHRVVESNF 278
>gi|194097398 protein tyrosine phosphatase, receptor type, G
precursor [Homo sapiens]
Length = 1445
Score = 126 bits (316), Expect = 3e-29
Identities = 88/268 (32%), Positives = 130/268 (48%), Gaps = 21/268 (7%)
Query: 29 WGYEEGV---EWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSP-NYVVCRDCEVTN 84
W Y W G +QSPI++ + AR +++L + + N
Sbjct: 60 WAYSGAYGPEHWVTSSVSCGGRHQSPIDILDQYARVGEEYQELQLDGFDNESSNKTWMKN 119
Query: 85 DGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWGREN-QRGSEHTVNFKAFPMELHLI 143
G T+ ++LK +SG LP F+ +V FHWG N GSEH++N + FP+E+ +
Sbjct: 120 TGKTVAILLKDDYFVSGAGLPG--RFKAEKVEFHWGHSNGSAGSEHSINGRRFPVEMQIF 177
Query: 144 HWNSTLFGSIDEAVGKPHGIAIIALFVQIG-KEHVGLKAVTEILQDIQYKGKSKTIPCFN 202
+N F S A+ + I +A+F Q+ +++ L + L+ + + K + F
Sbjct: 178 FYNPDDFDSFQTAISENRIIGAMAIFFQVSPRDNSALDPIIHGLKGVVHHEKETFLDPFV 237
Query: 203 PNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRT-----HV 257
LLP L Y+ Y GSLT PPCSE V WI+FR P+ IS Q+E F + T HV
Sbjct: 238 LRDLLPASL-GSYYRYTGSLTTPPCSEIVEWIVFRRPVPISYHQLEAFYSIFTTEQQDHV 296
Query: 258 KGAELVEGCDGILGDNFRPTQPLSDRVI 285
K E L +NFRP Q L DRV+
Sbjct: 297 KSVE-------YLRNNFRPQQRLHDRVV 317
>gi|9951923 carbonic anhydrase XI precursor [Homo sapiens]
Length = 328
Score = 121 bits (303), Expect = 8e-28
Identities = 87/276 (31%), Positives = 135/276 (48%), Gaps = 28/276 (10%)
Query: 29 WGYEEGVE---------WGLVFPD----ANGEYQSPINLNSREARYDPSLLDVRLSPNYV 75
W Y++ ++ WGLV A G+ QSP+++ + YDP L +RLS
Sbjct: 35 WSYKDNLQGNFVPGPPFWGLVNAAWSLCAVGKRQSPVDVELKRVLYDPFLPPLRLSTGGE 94
Query: 76 VCRDCEVTNDGHTIQVILKSKSVL--SGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNF 133
R + N G + + + V+ SGGPL H L E+R +G + GSEH +N
Sbjct: 95 KLRGT-LYNTGRHVSFLPAPRPVVNVSGGPLLYSHR--LSELRLLFGARDGAGSEHQINH 151
Query: 134 KAFPMELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQI---GKEHVGLKAVTEILQDIQ 190
+ F E+ LIH+N L+G+ A P+G+AI++LFV + + + + I
Sbjct: 152 QGFSAEVQLIHFNQELYGNFSAASRGPNGLAILSLFVNVASTSNPFLSRLLNRDTITRIS 211
Query: 191 YKGKSKTIPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEF 250
YK + + + L P+ + Y+GSL+ PPCSE VTWIL L I+ LQ+
Sbjct: 212 YKNDAYFLQDLSLELLFPESF--GFITYQGSLSTPPCSETVTWILIDRALNITSLQMHSL 269
Query: 251 RRLRTHVKGAELVEGCDGILGDNFRPTQPLSDRVIR 286
R L + +++ + G N RP QPL+ R +R
Sbjct: 270 RLLSQN-PPSQIFQSLSG----NSRPLQPLAHRALR 300
>gi|4502519 carbonic anhydrase IV precursor [Homo sapiens]
Length = 312
Score = 109 bits (273), Expect = 2e-24
Identities = 78/254 (30%), Positives = 131/254 (51%), Gaps = 15/254 (5%)
Query: 35 VEWGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSPNYVVCRDCEVTNDGHTIQVILK 94
V+WG + + QSPIN+ + +A+ D L S Y + V N+GH++ ++L+
Sbjct: 40 VKWG---GNCQKDRQSPINIVTTKAKVDKKLGRFFFS-GYDKKQTWTVQNNGHSVMMLLE 95
Query: 95 SKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFPMELHLIHWNST-LFGSI 153
+K+ +SGG LP ++ + ++ HW +GSEH+++ + F ME+H++H ++
Sbjct: 96 NKASISGGGLPAPYQAK--QLHLHWSDLPYKGSEHSLDGEHFAMEMHIVHEKEKGTSRNV 153
Query: 154 DEAVGKPHGIAIIALFVQIGKE-HVGLKAVTEILQDIQYKGKSKTIPCFNPNTLLP-DPL 211
EA IA++A V+ G + + G + + E L +I S T+ + LLP +
Sbjct: 154 KEAQDPEDEIAVLAFLVEAGTQVNEGFQPLVEALSNIPKPEMSTTMAESSLLDLLPKEEK 213
Query: 212 LRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHVKGAELVEGCDGILG 271
LR Y+ Y GSLT P C E V W +FR P+ + + QI F + + K + +
Sbjct: 214 LRHYFRYLGSLTTPTCDEKVVWTVFREPIQLHREQILAFSQKLYYDKEQTV------SMK 267
Query: 272 DNFRPTQPLSDRVI 285
DN RP Q L R +
Sbjct: 268 DNVRPLQQLGQRTV 281
>gi|91208428 protein tyrosine phosphatase, receptor-type, zeta1
precursor [Homo sapiens]
Length = 2315
Score = 108 bits (271), Expect = 4e-24
Identities = 72/272 (26%), Positives = 140/272 (51%), Gaps = 12/272 (4%)
Query: 25 EGVEWGYEEGVE---WGLVFPDANGEYQSPINLNSREARYDPSLLDVRLSP-NYVVCRDC 80
E + W Y + WG +P N QSPIN++ + + +L ++ + +
Sbjct: 34 EEIGWSYTGALNQKNWGKKYPTCNSPKQSPINIDEDLTQVNVNLKKLKFQGWDKTSLENT 93
Query: 81 EVTNDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWGRENQR--GSEHTVNFKAFPM 138
+ N G T+++ L + +SGG F+ ++ FHWG+ N GSEH++ + FP+
Sbjct: 94 FIHNTGKTVEINLTNDYRVSGGVSEM--VFKASKITFHWGKCNMSSDGSEHSLEGQKFPL 151
Query: 139 ELHLIHWNSTLFGSIDEAVGKPHGIAIIALFVQIG-KEHVGLKAVTEILQDIQYKGKSKT 197
E+ + +++ F S +EAV + +++ ++G +E++ KA+ + ++ + GK
Sbjct: 152 EMQIYCFDADRFSSFEEAVKGKGKLRALSILFEVGTEENLDFKAIIDGVESVSRFGKQAA 211
Query: 198 IPCFNPNTLLPDPLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRLRTHV 257
+ F LLP+ + Y++Y GSLT PPC++ V WI+F+ ++IS+ Q+ F + T
Sbjct: 212 LDPFILLNLLPNSTDK-YYIYNGSLTSPPCTDTVDWIVFKDTVSISESQLAVFCEVLTMQ 270
Query: 258 KGAELVEGCDGILGDNFRPTQPLSDRVIRAAF 289
+ ++ L +NFR Q R + +++
Sbjct: 271 QSGYVM--LMDYLQNNFREQQYKFSRQVFSSY 300
>gi|109134336 SH3-domain binding protein 5 (BTK-associated)
isoform a [Homo sapiens]
Length = 455
Score = 33.9 bits (76), Expect = 0.17
Identities = 23/59 (38%), Positives = 29/59 (49%), Gaps = 7/59 (11%)
Query: 8 EDTVAFPEKEEDEEEEEEGVEWGYEEGVEWGLVFPDANGEY----QSPINLNSREARYD 62
E P ++EEEEEEG+E G EE E V P GE QS ++N RE +
Sbjct: 12 EPAEILPPARDEEEEEEEGMEQGLEEEEE---VDPRIQGELEKLNQSTDDINRRETELE 67
>gi|113204617 skeletal muscle ryanodine receptor isoform 2 [Homo
sapiens]
Length = 5033
Score = 33.1 bits (74), Expect = 0.29
Identities = 15/26 (57%), Positives = 20/26 (76%)
Query: 15 EKEEDEEEEEEGVEWGYEEGVEWGLV 40
EKE++E+EEEE E EEG+E GL+
Sbjct: 1902 EKEDEEKEEEEAAEGEKEEGLEEGLL 1927
Score = 30.4 bits (67), Expect = 1.9
Identities = 18/33 (54%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
Query: 4 LSFIEDTVAFPEKEEDEEEEEEGVEWGYEEGVE 36
L IE V F E+EE+E+EEEEG E EE E
Sbjct: 1863 LKMIEPEV-FTEEEEEEDEEEEGEEEDEEEKEE 1894
>gi|113204615 skeletal muscle ryanodine receptor isoform 1 [Homo
sapiens]
Length = 5038
Score = 33.1 bits (74), Expect = 0.29
Identities = 15/26 (57%), Positives = 20/26 (76%)
Query: 15 EKEEDEEEEEEGVEWGYEEGVEWGLV 40
EKE++E+EEEE E EEG+E GL+
Sbjct: 1902 EKEDEEKEEEEAAEGEKEEGLEEGLL 1927
Score = 30.4 bits (67), Expect = 1.9
Identities = 18/33 (54%), Positives = 21/33 (63%), Gaps = 1/33 (3%)
Query: 4 LSFIEDTVAFPEKEEDEEEEEEGVEWGYEEGVE 36
L IE V F E+EE+E+EEEEG E EE E
Sbjct: 1863 LKMIEPEV-FTEEEEEEDEEEEGEEEDEEEKEE 1894
>gi|239750077 PREDICTED: hypothetical protein [Homo sapiens]
Length = 903
Score = 32.0 bits (71), Expect = 0.65
Identities = 20/55 (36%), Positives = 26/55 (47%)
Query: 83 TNDGHTIQVILKSKSVLSGGPLPQGHEFELYEVRFHWGRENQRGSEHTVNFKAFP 137
T G VI S S SG P P+ + + H GRE QR + T+ F A+P
Sbjct: 764 TGSGPDTTVISFSSSRASGPPKPRTSRILGFPLCAHSGREAQRTPQTTLRFPAWP 818
>gi|31543392 peroxisome proliferator-activated receptor gamma,
coactivator 1 beta [Homo sapiens]
Length = 1023
Score = 32.0 bits (71), Expect = 0.65
Identities = 15/24 (62%), Positives = 17/24 (70%)
Query: 15 EKEEDEEEEEEGVEWGYEEGVEWG 38
++EEDEEEEEE E EE EWG
Sbjct: 429 QEEEDEEEEEEEEEEEKEEEEEWG 452
>gi|239757628 PREDICTED: similar to hCG1646661 [Homo sapiens]
Length = 190
Score = 31.6 bits (70), Expect = 0.85
Identities = 16/44 (36%), Positives = 21/44 (47%)
Query: 210 PLLRDYWVYEGSLTIPPCSEGVTWILFRYPLTISQLQIEEFRRL 253
P Y + GSLT P C V W +F P+ I +Q+ F L
Sbjct: 98 PNTSSYCRFAGSLTPPDCEPTVLWTVFEDPIPIRWVQMTLFYTL 141
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.319 0.139 0.431
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 12,428,018
Number of Sequences: 37866
Number of extensions: 602447
Number of successful extensions: 5621
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 60
Number of HSP's successfully gapped in prelim test: 11
Number of HSP's that attempted gapping in prelim test: 5091
Number of HSP's gapped (non-prelim): 281
length of query: 290
length of database: 18,247,518
effective HSP length: 101
effective length of query: 189
effective length of database: 14,423,052
effective search space: 2725956828
effective search space used: 2725956828
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 61 (28.1 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.