Guide to the Human Genome
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Search of human proteins with 219842333

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|219842333 glutathione S-transferase kappa 1 isoform c [Homo
sapiens]
         (214 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|219842333 glutathione S-transferase kappa 1 isoform c [Homo s...   438   e-123
gi|7705704 glutathione S-transferase kappa 1 isoform a [Homo sap...   429   e-121
gi|219842335 glutathione S-transferase kappa 1 isoform d [Homo s...   319   1e-87
gi|219842317 glutathione S-transferase kappa 1 isoform b [Homo s...   268   3e-72
gi|225543215 antigen identified by monoclonal antibody Ki-67 iso...    30   1.5  
gi|103472005 antigen identified by monoclonal antibody Ki-67 iso...    30   1.5  
gi|41349466 PR domain containing 11 [Homo sapiens]                     29   3.4  
gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Ho...    28   7.6  
gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Ho...    28   7.6  

>gi|219842333 glutathione S-transferase kappa 1 isoform c [Homo
           sapiens]
          Length = 214

 Score =  438 bits (1126), Expect = e-123
 Identities = 214/214 (100%), Positives = 214/214 (100%)

Query: 1   MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP 60
           MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP
Sbjct: 1   MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP 60

Query: 61  RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE 120
           RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE
Sbjct: 61  RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE 120

Query: 121 LWMRVWSRAAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGAFGLPITVAHVDG 180
           LWMRVWSRAAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGAFGLPITVAHVDG
Sbjct: 121 LWMRVWSRAAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGAFGLPITVAHVDG 180

Query: 181 QTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL 214
           QTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL
Sbjct: 181 QTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL 214


>gi|7705704 glutathione S-transferase kappa 1 isoform a [Homo
           sapiens]
          Length = 226

 Score =  429 bits (1103), Expect = e-121
 Identities = 214/226 (94%), Positives = 214/226 (94%), Gaps = 12/226 (5%)

Query: 1   MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP 60
           MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP
Sbjct: 1   MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP 60

Query: 61  RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE 120
           RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE
Sbjct: 61  RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE 120

Query: 121 LWMRVWSR------------AAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGA 168
           LWMRVWSR            AAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGA
Sbjct: 121 LWMRVWSRNEDITEPQSILAAAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGA 180

Query: 169 FGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL 214
           FGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL
Sbjct: 181 FGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL 226


>gi|219842335 glutathione S-transferase kappa 1 isoform d [Homo
           sapiens]
          Length = 183

 Score =  319 bits (818), Expect = 1e-87
 Identities = 171/226 (75%), Positives = 171/226 (75%), Gaps = 55/226 (24%)

Query: 1   MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP 60
           MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDS         
Sbjct: 1   MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDS--------- 51

Query: 61  RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE 120
                                             GSLSAMRFLTAVNLEHPEMLEKASRE
Sbjct: 52  ----------------------------------GSLSAMRFLTAVNLEHPEMLEKASRE 77

Query: 121 LWMRVWSR------------AAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGA 168
           LWMRVWSR            AAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGA
Sbjct: 78  LWMRVWSRNEDITEPQSILAAAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGA 137

Query: 169 FGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL 214
           FGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL
Sbjct: 138 FGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL 183


>gi|219842317 glutathione S-transferase kappa 1 isoform b [Homo
           sapiens]
          Length = 282

 Score =  268 bits (684), Expect = 3e-72
 Identities = 128/130 (98%), Positives = 129/130 (99%)

Query: 1   MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP 60
           MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP
Sbjct: 1   MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP 60

Query: 61  RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE 120
           RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE
Sbjct: 61  RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE 120

Query: 121 LWMRVWSRAA 130
           LWMRVWSR +
Sbjct: 121 LWMRVWSRVS 130



 Score =  175 bits (443), Expect = 3e-44
 Identities = 86/86 (100%), Positives = 86/86 (100%)

Query: 129 AAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGAFGLPITVAHVDGQTHMLFGS 188
           AAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGAFGLPITVAHVDGQTHMLFGS
Sbjct: 197 AAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGAFGLPITVAHVDGQTHMLFGS 256

Query: 189 DRMELLAHLLGEKWMGPIPPAVNARL 214
           DRMELLAHLLGEKWMGPIPPAVNARL
Sbjct: 257 DRMELLAHLLGEKWMGPIPPAVNARL 282


>gi|225543215 antigen identified by monoclonal antibody Ki-67
           isoform 2 [Homo sapiens]
          Length = 2896

 Score = 30.0 bits (66), Expect = 1.5
 Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 3/57 (5%)

Query: 112 EMLEKASRELWMRVWSRAAEKAGMSAEQAQGLLEKIATPKVKNQL---KETTEAACR 165
           ++L+ A+R   M+ W R  ++   S E   G  E   TP    +    ++TT+ AC+
Sbjct: 714 QILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACK 770


>gi|103472005 antigen identified by monoclonal antibody Ki-67 isoform
            1 [Homo sapiens]
          Length = 3256

 Score = 30.0 bits (66), Expect = 1.5
 Identities = 16/57 (28%), Positives = 28/57 (49%), Gaps = 3/57 (5%)

Query: 112  EMLEKASRELWMRVWSRAAEKAGMSAEQAQGLLEKIATPKVKNQL---KETTEAACR 165
            ++L+ A+R   M+ W R  ++   S E   G  E   TP    +    ++TT+ AC+
Sbjct: 1074 QILDPAARVTGMKKWPRTPKEEAQSLEDLAGFKELFQTPGPSEESMTDEKTTKIACK 1130


>gi|41349466 PR domain containing 11 [Homo sapiens]
          Length = 511

 Score = 28.9 bits (63), Expect = 3.4
 Identities = 15/45 (33%), Positives = 23/45 (51%)

Query: 91  MLEKGSLSAMRFLTAVNLEHPEMLEKASRELWMRVWSRAAEKAGM 135
           ML+ G L     L    LE PE  + A + +WMR+ S    ++G+
Sbjct: 464 MLKSGKLPEPPVLPPQVLELPEFSDPAGKLVWMRLLSEGRVRSGL 508


>gi|12751473 DNA cytosine methyltransferase 3 alpha isoform a [Homo
           sapiens]
          Length = 912

 Score = 27.7 bits (60), Expect = 7.6
 Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 6/38 (15%)

Query: 111 PEMLEKASRELWMRVWSRAAEK-----AGMSA-EQAQG 142
           P  + K  R+ W+  W R AEK     AGM+A E+ QG
Sbjct: 195 PYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQG 232


>gi|28559069 DNA cytosine methyltransferase 3 alpha isoform a [Homo
           sapiens]
          Length = 912

 Score = 27.7 bits (60), Expect = 7.6
 Identities = 16/38 (42%), Positives = 21/38 (55%), Gaps = 6/38 (15%)

Query: 111 PEMLEKASRELWMRVWSRAAEK-----AGMSA-EQAQG 142
           P  + K  R+ W+  W R AEK     AGM+A E+ QG
Sbjct: 195 PYYISKRKRDEWLARWKREAEKKAKVIAGMNAVEENQG 232


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.322    0.137    0.425 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 8,601,646
Number of Sequences: 37866
Number of extensions: 350581
Number of successful extensions: 798
Number of sequences better than 10.0: 9
Number of HSP's better than 10.0 without gapping: 5
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 787
Number of HSP's gapped (non-prelim): 13
length of query: 214
length of database: 18,247,518
effective HSP length: 98
effective length of query: 116
effective length of database: 14,536,650
effective search space: 1686251400
effective search space used: 1686251400
T: 11
A: 40
X1: 16 ( 7.4 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.9 bits)
S2: 59 (27.3 bits)

Search results were obtained with NCBI BLAST and RefSeq entries.


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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.

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