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Search of human proteins with 218505703
BLASTP 2.2.11 [Jun-05-2005]
Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs", Nucleic Acids Res. 25:3389-3402.
Query= gi|218505703 von Willebrand factor A domain containing 3A [Homo
sapiens]
(1184 letters)
Database: hs.faa
37,866 sequences; 18,247,518 total letters
Searching..................................................done
Score E
Sequences producing significant alignments: (bits) Value
gi|218505703 von Willebrand factor A domain containing 3A [Homo ... 2385 0.0
gi|118918435 von Willebrand factor A domain containing 3B [Homo ... 177 7e-44
gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens] 57 1e-07
gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo ... 56 2e-07
gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor ... 50 1e-05
gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor... 50 1e-05
gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor... 50 1e-05
gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens] 49 2e-05
gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein [... 45 5e-04
gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens] 43 0.002
gi|194306644 BCSC-1 isoform 1 [Homo sapiens] 42 0.003
gi|38195080 BCSC-1 isoform 1 [Homo sapiens] 42 0.003
gi|110611231 chloride channel accessory 1 precursor [Homo sapiens] 40 0.017
gi|239735575 otoancorin isoform 3 [Homo sapiens] 39 0.038
gi|24638452 otoancorin isoform 2 [Homo sapiens] 39 0.038
gi|77404409 otoancorin isoform 1 [Homo sapiens] 39 0.038
gi|38195082 BCSC-1 isoform 2 [Homo sapiens] 37 0.085
gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens] 35 0.55
gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens] 35 0.55
gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens] 34 0.94
gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens] 34 0.94
gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens] 34 0.94
gi|45504376 synaptotagmin VI [Homo sapiens] 33 1.2
gi|157412247 RUN and SH3 domain containing 1 isoform b [Homo sap... 33 1.6
gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo sap... 33 1.6
gi|116517292 cut-like 2 [Homo sapiens] 33 1.6
gi|210147462 von Willebrand factor A domain containing 5B1 [Homo... 32 2.7
gi|81295809 pericentrin [Homo sapiens] 32 3.6
gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens] 32 4.7
gi|12545406 RAS p21 protein activator 1 isoform 2 [Homo sapiens] 32 4.7
>gi|218505703 von Willebrand factor A domain containing 3A [Homo
sapiens]
Length = 1184
Score = 2385 bits (6180), Expect = 0.0
Identities = 1184/1184 (100%), Positives = 1184/1184 (100%)
Query: 1 MKKYRKISIGCFAMATQTSHVFHGQENMFLENHCIRRNTGRDSKKPLKQKNMNGLGQNSD 60
MKKYRKISIGCFAMATQTSHVFHGQENMFLENHCIRRNTGRDSKKPLKQKNMNGLGQNSD
Sbjct: 1 MKKYRKISIGCFAMATQTSHVFHGQENMFLENHCIRRNTGRDSKKPLKQKNMNGLGQNSD 60
Query: 61 NGLLVTHVNQTQDLLRLQGSETQSSDWEDSEDWLSAHSLKCQKLTLADLISQGTEVLEEG 120
NGLLVTHVNQTQDLLRLQGSETQSSDWEDSEDWLSAHSLKCQKLTLADLISQGTEVLEEG
Sbjct: 61 NGLLVTHVNQTQDLLRLQGSETQSSDWEDSEDWLSAHSLKCQKLTLADLISQGTEVLEEG 120
Query: 121 TNVVQKICFSTQIIRHFESKLSDTIEVYQERIQWLTENSKKAFGLIKGARVSILIDVSAI 180
TNVVQKICFSTQIIRHFESKLSDTIEVYQERIQWLTENSKKAFGLIKGARVSILIDVSAI
Sbjct: 121 TNVVQKICFSTQIIRHFESKLSDTIEVYQERIQWLTENSKKAFGLIKGARVSILIDVSAI 180
Query: 181 SSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSASTLQELKLWVKT 240
SSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSASTLQELKLWVKT
Sbjct: 181 SSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSASTLQELKLWVKT 240
Query: 241 LQPDGGSNLLQALKKIFTLKGLDSLVAIMRSCPDQPSEILSDYIQQSTMGRDLIIHFITY 300
LQPDGGSNLLQALKKIFTLKGLDSLVAIMRSCPDQPSEILSDYIQQSTMGRDLIIHFITY
Sbjct: 241 LQPDGGSNLLQALKKIFTLKGLDSLVAIMRSCPDQPSEILSDYIQQSTMGRDLIIHFITY 300
Query: 301 RCDDQMPPAVLKNLAEAVRGYYHCYSPKMEHYTSRDMDELLAEIQKAQSLLSHVQALQHS 360
RCDDQMPPAVLKNLAEAVRGYYHCYSPKMEHYTSRDMDELLAEIQKAQSLLSHVQALQHS
Sbjct: 301 RCDDQMPPAVLKNLAEAVRGYYHCYSPKMEHYTSRDMDELLAEIQKAQSLLSHVQALQHS 360
Query: 361 SPCEALTCTMEEISTEITNGPLISLLPKPPKHDAPLTIEFPNLDKTSAEWLKVNGLKAKK 420
SPCEALTCTMEEISTEITNGPLISLLPKPPKHDAPLTIEFPNLDKTSAEWLKVNGLKAKK
Sbjct: 361 SPCEALTCTMEEISTEITNGPLISLLPKPPKHDAPLTIEFPNLDKTSAEWLKVNGLKAKK 420
Query: 421 LSLYQVLAPNAFSPVEEFVPILQKTVSSTIHEKAMIQFEWHDGTVKNIHVDPPFLYKYQQ 480
LSLYQVLAPNAFSPVEEFVPILQKTVSSTIHEKAMIQFEWHDGTVKNIHVDPPFLYKYQQ
Sbjct: 421 LSLYQVLAPNAFSPVEEFVPILQKTVSSTIHEKAMIQFEWHDGTVKNIHVDPPFLYKYQQ 480
Query: 481 QLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQ 540
QLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQ
Sbjct: 481 QLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQ 540
Query: 541 LSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVD 600
LSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVD
Sbjct: 541 LSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVD 600
Query: 601 FKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFYVGEPKMDTTPPA 660
FKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFYVGEPKMDTTPPA
Sbjct: 601 FKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFYVGEPKMDTTPPA 660
Query: 661 RYASHTDTAAAYKEVTRAAGGRFHWFGDTGIYESDDINSIMSEMEKALNYSQKCAFLMAS 720
RYASHTDTAAAYKEVTRAAGGRFHWFGDTGIYESDDINSIMSEMEKALNYSQKCAFLMAS
Sbjct: 661 RYASHTDTAAAYKEVTRAAGGRFHWFGDTGIYESDDINSIMSEMEKALNYSQKCAFLMAS 720
Query: 721 LKNHSGKVLGSSALPKEKPKTLQLRSQPKKLCPPRPTVPLGARMSIKDDPDREKSPPLKS 780
LKNHSGKVLGSSALPKEKPKTLQLRSQPKKLCPPRPTVPLGARMSIKDDPDREKSPPLKS
Sbjct: 721 LKNHSGKVLGSSALPKEKPKTLQLRSQPKKLCPPRPTVPLGARMSIKDDPDREKSPPLKS 780
Query: 781 LKWRPLSSRVGISPAAAQPTKEGMMELRRKTKSREAETSLLLFYTEKGNDVGSVYKKYPQ 840
LKWRPLSSRVGISPAAAQPTKEGMMELRRKTKSREAETSLLLFYTEKGNDVGSVYKKYPQ
Sbjct: 781 LKWRPLSSRVGISPAAAQPTKEGMMELRRKTKSREAETSLLLFYTEKGNDVGSVYKKYPQ 840
Query: 841 GRGLRRTSSSIDLPRKDTVCSSQEWVAKYGLKKLKLEISRCMGPNCTHQKSGQRSASAKH 900
GRGLRRTSSSIDLPRKDTVCSSQEWVAKYGLKKLKLEISRCMGPNCTHQKSGQRSASAKH
Sbjct: 841 GRGLRRTSSSIDLPRKDTVCSSQEWVAKYGLKKLKLEISRCMGPNCTHQKSGQRSASAKH 900
Query: 901 CSIFPSVEIHGVVRHIQWTPREMEVYIRHLEKVLRRYVQRLQWLLSGSRRLFGTVLESKV 960
CSIFPSVEIHGVVRHIQWTPREMEVYIRHLEKVLRRYVQRLQWLLSGSRRLFGTVLESKV
Sbjct: 901 CSIFPSVEIHGVVRHIQWTPREMEVYIRHLEKVLRRYVQRLQWLLSGSRRLFGTVLESKV 960
Query: 961 CILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAAC 1020
CILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAAC
Sbjct: 961 CILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAAC 1020
Query: 1021 HEAMQWVTHLQAQGSTSILQALLKAFSFHDLEGLYLLTDGKPDTSCSLVLNEVQKLREKR 1080
HEAMQWVTHLQAQGSTSILQALLKAFSFHDLEGLYLLTDGKPDTSCSLVLNEVQKLREKR
Sbjct: 1021 HEAMQWVTHLQAQGSTSILQALLKAFSFHDLEGLYLLTDGKPDTSCSLVLNEVQKLREKR 1080
Query: 1081 DVKVHTISLNCSDRAAVEFLRKLASFTGGRYHCPVGEDTLSKIHSLLTKGFINEKDPTLP 1140
DVKVHTISLNCSDRAAVEFLRKLASFTGGRYHCPVGEDTLSKIHSLLTKGFINEKDPTLP
Sbjct: 1081 DVKVHTISLNCSDRAAVEFLRKLASFTGGRYHCPVGEDTLSKIHSLLTKGFINEKDPTLP 1140
Query: 1141 PFEGDDLRILAQEITKARSFLWQAQSFRSQLQKKNDAEPKVTLS 1184
PFEGDDLRILAQEITKARSFLWQAQSFRSQLQKKNDAEPKVTLS
Sbjct: 1141 PFEGDDLRILAQEITKARSFLWQAQSFRSQLQKKNDAEPKVTLS 1184
>gi|118918435 von Willebrand factor A domain containing 3B [Homo
sapiens]
Length = 1294
Score = 177 bits (448), Expect = 7e-44
Identities = 223/986 (22%), Positives = 392/986 (39%), Gaps = 181/986 (18%)
Query: 72 QDLLRLQGSETQSSDWED-----SEDWLSAHSLKCQKLTLADLISQ-------------G 113
Q L R +G +D + SE WL H LK KLTL ++SQ G
Sbjct: 13 QQLQRQEGWINTKTDLAEQSLISSEKWLQLHGLKSNKLTLKQILSQIGFPHCEDYVASLG 72
Query: 114 TEVL--------------EEGTNVVQKICFSTQIIRHFESKLSDTIEVYQERIQWLTENS 159
V E+G V + +++I F L+ +E Y++R+ WLT S
Sbjct: 73 RPVASRYADGLFPQLYRAEDGR--VYNLTAKSELIYQFVEHLTQAVESYKQRMDWLTSKS 130
Query: 160 KKAFGLIKGARVSILIDVSAISSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSL 219
++ FG+I V+I++D I G + + ++ L ++ EQ++H + ++
Sbjct: 131 RQIFGVILEQCVTIVLDFGGILEG-ELDLCREALTMVLQEQVAHITEFNIIRVSQEPVKW 189
Query: 220 WPDPMEVSASTLQELKLWVKTLQPD---GGSNLLQALKKIFTLKGLDSLVA-IMRSCPDQ 275
+ V+ ++ WV+ L + + L AL + K ++S+ ++ P++
Sbjct: 190 QENATPVTEQSIATAISWVEKLTVELTVSEAGRLDALLEAGRDKTIESIYYFVVGDVPEE 249
Query: 276 PSEILSDYIQQSTMGRDLIIHFITYRCDDQMPPAVLKNLAEAVRGYYHCYSPKME----- 330
E+L Q + ++ +++ + A LK+L+ +H ++ + E
Sbjct: 250 SKELLL----QRALEIPCPVYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAERTECVEFP 305
Query: 331 HYTSRDMDELLA-------------------------EIQKAQSLLSHVQALQHSSP--- 362
++++D D ++ E+++A S L+ +Q L P
Sbjct: 306 AFSTKDGDNVMTWNSRKLKGKLPPGAGVREDVFLVWQEMEEACSTLAQIQRLVAEPPKPD 365
Query: 363 CEALTCTMEEISTEITNGPLISLLPKPPKHDAPLTIEFPNLDKTSAEWLKVNGLKAKKLS 422
+ C E S EI + P + S WL+ GLKA+KLS
Sbjct: 366 VATVDCESETTSVEIASNPEDTW--------------------DSKTWLQKYGLKAQKLS 405
Query: 423 LYQVLAPNAF-----------SPVEEFVPILQKTVSSTIHEKAMIQF---EWHDGTVKNI 468
LY VLA +F P E V +T T+H K +F W DG++ ++
Sbjct: 406 LYDVLADCSFRHADGVVDIKAKPENESVQTSAETNKKTVHAKYCSRFVHAPWKDGSLVHV 465
Query: 469 HVDPPFLYKYQQQLSRAMRMYERRIEWLSLASRRIWGTVCEKRVVVLLDISATNSMYIIH 528
++ Y +++ A+ RRI+WL S+ ++G + + +L+D S + +
Sbjct: 466 NITKEKCKWYSERIHTALARIRRRIKWLQDGSQSLFGRLHNDCIYILIDTSHSMKSKLDL 525
Query: 529 IQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQSAWRWALNLRCRGSRN 588
++ + ++EQL K FN + F +WR ++ V+ +NL+ A W +++ S N
Sbjct: 526 VKDKIIQFIQEQLKYKSKFNFVKFDGQAVAWREQLAEVNEDNLEQAQSWIRDIKIGSSTN 585
Query: 589 VLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQDMPTLSAYMAEACGGCDLQLNVCLFY 648
LSAL+ A F DK ++Q IYL T G PDQ T+
Sbjct: 586 TLSALKTA----FADK---ETQAIYLLTDGRPDQPPETV--------------------- 617
Query: 649 VGEPKMDTTPPARYAS--HTDTAA--AYKEVTRAAGGRFHWFG-------DTGIYESDDI 697
+ + K P S + D A KEV GG FH++ +++D+
Sbjct: 618 IDQVKRFQEIPIYTISFNYNDEIANRFLKEVAALTGGEFHFYNFGCKDPTPPEAVQNEDL 677
Query: 698 NSIMSEMEKALNYSQKCAFLMA-SLKNHSGKVLGSSALPKEKPKTLQLRSQPKKLCPPRP 756
++ EME+ + +K L + SL K + + + S P+K P+
Sbjct: 678 TLLVKEMEQGHSDLEKMQDLYSESLIMDWWYNAEKDGDSKHQKEICSMISTPEKCAKPQS 737
Query: 757 TVPLGARMSIK--------DDPDREKSPPL--KSLKWRPLSSRV-GISPAAAQPTKEGMM 805
V S+ D +K L +S K L S++ + +A K+G+
Sbjct: 738 DVDSTQTSSLNMLKGPWGLSDQKVQKKKVLHAESTKTSLLRSQMSSLRSSACSERKDGLS 797
Query: 806 EL-RRKTKSREAETSLLLFYTEKGNDVGSVYKKYPQGRGLRRTSSSIDLPRKDTVCSSQE 864
R+T + E S+LL E+ D S K +G S D D SS+
Sbjct: 798 NASSRRTALSDKEMSILL--AEEWLDDKSSEKVTREG------SQVYDHDSSDV--SSEN 847
Query: 865 WVAKYGLKKLKLEISRCMGPNCTHQKSGQRSASAKHC------SIFPSVEI---HGVVRH 915
W+ YGL KL + + S KH +FP + +
Sbjct: 848 WLKTYGLVAKKLTLMDALSVAAVPHSSTYVPVLDKHVVSKVFDEVFPLAHVCNDTNKMTL 907
Query: 916 IQWTPREMEVYIRHLEKVLRRYVQRL 941
I ++ +Y R +E+ ++ Y +RL
Sbjct: 908 INPQGAKLNIYKRKVEQAIQSYEKRL 933
Score = 143 bits (361), Expect = 8e-34
Identities = 104/349 (29%), Positives = 169/349 (48%), Gaps = 49/349 (14%)
Query: 847 TSSSIDLPRKDTVCSSQEWVAKYGLKKLKLEISRCMGPNC-------------------- 886
TS I +DT S+ W+ KYGLK KL + + +C
Sbjct: 376 TSVEIASNPEDT-WDSKTWLQKYGLKAQKLSLYDVLA-DCSFRHADGVVDIKAKPENESV 433
Query: 887 -THQKSGQRSASAKHCSIFPSVEIH-GVVRHIQWTPREMEVYIRHLEKVLRRYVQRLQWL 944
T ++ +++ AK+CS F G + H+ T + + Y + L R +R++WL
Sbjct: 434 QTSAETNKKTVHAKYCSRFVHAPWKDGSLVHVNITKEKCKWYSERIHTALARIRRRIKWL 493
Query: 945 LSGSRRLFGTVLESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAES 1004
GS+ LFG + + IL+DTS SM L VK +++ I EQL K FN + F
Sbjct: 494 QDGSQSLFGRLHNDCIYILIDTSHSMKSKLDLVKDKIIQFIQEQL-KYKSKFNFVKFDGQ 552
Query: 1005 FQSWQDTLVETTDAACHEAMQWVTHLQAQGSTSILQALLKAFSFHDLEGLYLLTDGKPDT 1064
+W++ L E + +A W+ ++ ST+ L AL AF+ + + +YLLTDG+PD
Sbjct: 553 AVAWREQLAEVNEDNLEQAQSWIRDIKIGSSTNTLSALKTAFADKETQAIYLLTDGRPDQ 612
Query: 1065 SCSLVLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGGRYHCPVGEDTLSKIH 1124
V+++V++ +E + ++TIS N +D A FL+++A+ TGG +H
Sbjct: 613 PPETVIDQVKRFQE---IPIYTISFNYNDEIANRFLKEVAALTGGEFH------------ 657
Query: 1125 SLLTKGFINE--KDPTLP-PFEGDDLRILAQEITKARSFLWQAQSFRSQ 1170
F N KDPT P + +DL +L +E+ + S L + Q S+
Sbjct: 658 ------FYNFGCKDPTPPEAVQNEDLTLLVKEMEQGHSDLEKMQDLYSE 700
Score = 104 bits (259), Expect = 6e-22
Identities = 90/343 (26%), Positives = 158/343 (46%), Gaps = 26/343 (7%)
Query: 856 KDTVCSSQEWVAKYGLKKLKLEISRCMG----PNCTHQKS--GQRSASAKHCSIFPSVEI 909
+ ++ SS++W+ +GLK KL + + + P+C + G+ AS +FP +
Sbjct: 30 EQSLISSEKWLQLHGLKSNKLTLKQILSQIGFPHCEDYVASLGRPVASRYADGLFPQLYR 89
Query: 910 HGVVRHIQWTPREMEVY--IRHLEKVLRRYVQRLQWLLSGSRRLFGTVLESKVCILLDTS 967
R T + +Y + HL + + Y QR+ WL S SR++FG +LE V I+LD
Sbjct: 90 AEDGRVYNLTAKSELIYQFVEHLTQAVESYKQRMDWLTSKSRQIFGVILEQCVTIVLDFG 149
Query: 968 GSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTDAACHEAMQWV 1027
G + L + L +++ EQ+ + FN++ ++ WQ+ T+ + A+ WV
Sbjct: 150 GILEGELDLCREALTMVLQEQVAHITE-FNIIRVSQEPVKWQENATPVTEQSIATAISWV 208
Query: 1028 THLQAQGSTS---ILQALLKAFSFHDLEGLYLLTDGK-PDTSCSLVLNEVQKLREKRDVK 1083
L + + S L ALL+A +E +Y G P+ S L+L ++
Sbjct: 209 EKLTVELTVSEAGRLDALLEAGRDKTIESIYYFVVGDVPEESKELLLQRALEI----PCP 264
Query: 1084 VHTISLNCSDRAAVEFLRKLASFTGGRYHCPVGEDTLSKIHSLLTKGFIN-------EKD 1136
V+T+S N + FL+ L++ T R+H + + TK N +
Sbjct: 265 VYTVSFNARGEGTIAFLKDLSAKTHSRFHAFAERTECVEFPAFSTKDGDNVMTWNSRKLK 324
Query: 1137 PTLPPFEG--DDLRILAQEITKARSFLWQAQSFRSQLQKKNDA 1177
LPP G +D+ ++ QE+ +A S L Q Q ++ K + A
Sbjct: 325 GKLPPGAGVREDVFLVWQEMEEACSTLAQIQRLVAEPPKPDVA 367
Score = 46.2 bits (108), Expect = 2e-04
Identities = 32/101 (31%), Positives = 53/101 (52%), Gaps = 5/101 (4%)
Query: 404 DKTSAEWLKVNGLKAKKLSLYQVLAPNAFSPVEEFVPILQKTVSSTIHEKAMIQFEWHDG 463
D +S WLK GL AKKL+L L+ A +VP+L K V S + ++ +
Sbjct: 842 DVSSENWLKTYGLVAKKLTLMDALSVAAVPHSSTYVPVLDKHVVSKVFDEVFPLAHVCND 901
Query: 464 TVKNIHVDP--PFLYKYQQQLSRAMRMYERR---IEWLSLA 499
T K ++P L Y++++ +A++ YE+R I W +L+
Sbjct: 902 TNKMTLINPQGAKLNIYKRKVEQAIQSYEKRLNKIVWRALS 942
>gi|31542984 inter-alpha (globulin) inhibitor H4 [Homo sapiens]
Length = 930
Score = 57.0 bits (136), Expect = 1e-07
Identities = 37/120 (30%), Positives = 59/120 (49%), Gaps = 5/120 (4%)
Query: 506 TVCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVP 565
T K VV ++D S + S I + + + LS +D FNLI F + WRP +VP
Sbjct: 269 TTMPKNVVFVIDKSGSMSGRKIQQTREALIKILDDLSPRDQFNLIVFSTEATQWRPSLVP 328
Query: 566 VSHNNLQSAWRWALNLRCRGSRNVLSALRKAVE-VDFKDKDKHQSQG----IYLFTGGIP 620
S N+ A +A ++ G N+ A+ AV+ +D ++++ +G I L T G P
Sbjct: 329 ASAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTDGDP 388
Score = 53.9 bits (128), Expect = 9e-07
Identities = 45/169 (26%), Positives = 72/169 (42%), Gaps = 15/169 (8%)
Query: 954 TVLESKVCILLDTSGSM-GPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTL 1012
T + V ++D SGSM G +QQ + L+ ++ + + D FNL+ F+ W+ +L
Sbjct: 269 TTMPKNVVFVIDKSGSMSGRKIQQTREALIKILDDLSPR--DQFNLIVFSTEATQWRPSL 326
Query: 1013 VETTDAACHEAMQWVTHLQAQGSTSILQALLKAFSFHDLEG------------LYLLTDG 1060
V + ++A + +QA G T+I A+L A D + LLTDG
Sbjct: 327 VPASAENVNKARSFAAGIQALGGTNINDAMLMAVQLLDSSNQEERLPEGSVSLIILLTDG 386
Query: 1061 KPDTSCSLVLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGG 1109
P + + +RE + L + FL KLA GG
Sbjct: 387 DPTVGETNPRSIQNNVREAVSGRYSLFCLGFGFDVSYAFLEKLALDNGG 435
Score = 36.2 bits (82), Expect = 0.19
Identities = 36/155 (23%), Positives = 70/155 (45%), Gaps = 16/155 (10%)
Query: 171 VSILIDVSAISSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSAST 230
V +ID S SG + ++ ++ L+ ++D+ LS +++ ++ F T A P + SA
Sbjct: 275 VVFVIDKSGSMSGRKIQQTREALIKILDD-LSPRDQFNLIVFSTEATQWRPSLVPASAEN 333
Query: 231 LQELKLWVKTLQPDGGSNLLQALKKIFTLKGLDSLVAIMRSCPDQPSEILSDYIQQSTMG 290
+ + + + +Q GG+N+ A+ + ++ LDS R S I+ T+G
Sbjct: 334 VNKARSFAAGIQALGGTNINDAM--LMAVQLLDSSNQEERLPEGSVSLIILLTDGDPTVG 391
Query: 291 RDLIIHFITYRCDDQMPPAVLKNLAEAVRGYYHCY 325
+ P ++ N+ EAV G Y +
Sbjct: 392 -------------ETNPRSIQNNVREAVSGRYSLF 413
>gi|70778918 inter-alpha globulin inhibitor H2 polypeptide [Homo
sapiens]
Length = 946
Score = 56.2 bits (134), Expect = 2e-07
Identities = 43/167 (25%), Positives = 82/167 (49%), Gaps = 15/167 (8%)
Query: 956 LESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVET 1015
+ + ++D SGSM + E + I + LR D F+++ F ++ ++W++ L+
Sbjct: 307 IPKNILFVIDVSGSMWGVKMKQTVEAMKTILDDLR-AEDHFSVIDFNQNIRTWRNDLISA 365
Query: 1016 TDAACHEAMQWVTHLQAQGSTSILQALLKA-FSFHDLEGLYLL-----------TDGKPD 1063
T +A +++ +Q G T+I +ALL+A F ++ L LL +DG P
Sbjct: 366 TKTQVADAKRYIEKIQPSGGTNINEALLRAIFILNEANNLGLLDPNSVSLIILVSDGDP- 424
Query: 1064 TSCSLVLNEVQK-LREKRDVKVHTISLNCSDRAAVEFLRKLASFTGG 1109
T L L+++QK ++E + SL +FL++L++ G
Sbjct: 425 TVGELKLSKIQKNVKENIQDNISLFSLGMGFDVDYDFLKRLSNENHG 471
Score = 38.1 bits (87), Expect = 0.050
Identities = 23/96 (23%), Positives = 53/96 (55%), Gaps = 2/96 (2%)
Query: 171 VSILIDVSAISSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSAST 230
+ +IDVS G + ++ + + +++D+ L ++ V+ F N + D + + +
Sbjct: 311 ILFVIDVSGSMWGVKMKQTVEAMKTILDD-LRAEDHFSVIDFNQNIRTWRNDLISATKTQ 369
Query: 231 LQELKLWVKTLQPDGGSNLLQA-LKKIFTLKGLDSL 265
+ + K +++ +QP GG+N+ +A L+ IF L ++L
Sbjct: 370 VADAKRYIEKIQPSGGTNINEALLRAIFILNEANNL 405
>gi|49355778 inter-alpha trypsin inhibitor heavy chain precursor 5
isoform 3 [Homo sapiens]
Length = 702
Score = 50.1 bits (118), Expect = 1e-05
Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 15/162 (9%)
Query: 956 LESKVCILLDTSGSM-GPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVE 1014
L V +LD+S SM G L+Q K L ++ + + D F+++ F+ + W+D L+
Sbjct: 292 LPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQ--DRFSIIGFSNRIKVWKDHLIS 349
Query: 1015 TTDAACHEAMQWVTHLQAQGSTSILQALLKAFSF------------HDLEGLYLLTDGKP 1062
T + + ++ H+ G T I AL +A + + LTDGKP
Sbjct: 350 VTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKP 409
Query: 1063 DTSCSLVLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLA 1104
+ L + RE +V ++ + L KL+
Sbjct: 410 TVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLS 451
>gi|153945780 inter-alpha trypsin inhibitor heavy chain precursor 5
isoform 1 [Homo sapiens]
Length = 956
Score = 50.1 bits (118), Expect = 1e-05
Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 15/162 (9%)
Query: 956 LESKVCILLDTSGSM-GPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVE 1014
L V +LD+S SM G L+Q K L ++ + + D F+++ F+ + W+D L+
Sbjct: 292 LPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQ--DRFSIIGFSNRIKVWKDHLIS 349
Query: 1015 TTDAACHEAMQWVTHLQAQGSTSILQALLKAFSF------------HDLEGLYLLTDGKP 1062
T + + ++ H+ G T I AL +A + + LTDGKP
Sbjct: 350 VTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKP 409
Query: 1063 DTSCSLVLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLA 1104
+ L + RE +V ++ + L KL+
Sbjct: 410 TVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLS 451
>gi|153945711 inter-alpha trypsin inhibitor heavy chain precursor 5
isoform 2 [Homo sapiens]
Length = 742
Score = 50.1 bits (118), Expect = 1e-05
Identities = 39/162 (24%), Positives = 68/162 (41%), Gaps = 15/162 (9%)
Query: 956 LESKVCILLDTSGSM-GPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVE 1014
L V +LD+S SM G L+Q K L ++ + + D F+++ F+ + W+D L+
Sbjct: 78 LPKNVVFVLDSSASMVGTKLRQTKDALFTILHDLRPQ--DRFSIIGFSNRIKVWKDHLIS 135
Query: 1015 TTDAACHEAMQWVTHLQAQGSTSILQALLKAFSF------------HDLEGLYLLTDGKP 1062
T + + ++ H+ G T I AL +A + + LTDGKP
Sbjct: 136 VTPDSIRDGKVYIHHMSPTGGTDINGALQRAIRLLNKYVAHSGIGDRSVSLIVFLTDGKP 195
Query: 1063 DTSCSLVLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLA 1104
+ L + RE +V ++ + L KL+
Sbjct: 196 TVGETHTLKILNNTREAARGQVCIFTIGIGNDVDFRLLEKLS 237
>gi|38348336 inter-alpha (globulin) inhibitor H5-like [Homo sapiens]
Length = 1313
Score = 49.3 bits (116), Expect = 2e-05
Identities = 45/168 (26%), Positives = 80/168 (47%), Gaps = 24/168 (14%)
Query: 956 LESKVCILLDTSGSM-GPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQ-DTLV 1013
+E V ++D S SM G ++Q KT + +++ + + D FN++SF+++ W+ +
Sbjct: 280 MEKNVVFVIDVSSSMFGTKMEQTKTAMNVILSDL--QANDYFNIISFSDTVNVWKAGGSI 337
Query: 1014 ETTDAACHEAMQWVTHLQAQGSTSILQALLKAFSFHDLEG--------------LYLLTD 1059
+ T H A ++ ++A G T + ALL A S + + LTD
Sbjct: 338 QATIQNVHSAKDYLHCMEADGWTDVNSALLAAASVLNHSNQEPGRGPSVGRIPLIIFLTD 397
Query: 1060 GKPD---TSCSLVLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLA 1104
G+P T+ S++L+ V R+ +V SL D A LR+L+
Sbjct: 398 GEPTAGVTTPSVILSNV---RQALGHRVSLFSLAFGDDADFTLLRRLS 442
Score = 34.3 bits (77), Expect = 0.72
Identities = 27/95 (28%), Positives = 50/95 (52%), Gaps = 7/95 (7%)
Query: 509 EKRVVVLLDISATNSMYIIHIQHS---LRLLLEEQLSNKDCFNLIAFGSTIESWRP-EMV 564
EK VV ++D+S+ SM+ ++ + + ++L + +N D FN+I+F T+ W+ +
Sbjct: 281 EKNVVFVIDVSS--SMFGTKMEQTKTAMNVILSDLQAN-DYFNIISFSDTVNVWKAGGSI 337
Query: 565 PVSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEV 599
+ N+ SA + + G +V SAL A V
Sbjct: 338 QATIQNVHSAKDYLHCMEADGWTDVNSALLAAASV 372
>gi|133925809 inter-alpha (globulin) inhibitor H3 preproprotein
[Homo sapiens]
Length = 890
Score = 44.7 bits (104), Expect = 5e-04
Identities = 23/102 (22%), Positives = 48/102 (47%)
Query: 507 VCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVPV 566
V K V ++DIS + + + L + E + +D N I F + +W+ +V
Sbjct: 280 VVPKNVAFVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSGDVSTWKEHLVQA 339
Query: 567 SHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVDFKDKDKHQ 608
+ NLQ A + ++ +G N+ L + + + K +++H+
Sbjct: 340 TPENLQEARTFVKSMEDKGMTNINDGLLRGISMLNKAREEHR 381
Score = 33.9 bits (76), Expect = 0.94
Identities = 23/96 (23%), Positives = 50/96 (52%), Gaps = 8/96 (8%)
Query: 171 VSILIDVSAISSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPM-EVSAS 229
V+ +ID+S +G + E+ ++ L+ ++++ F+L G S W + + + +
Sbjct: 285 VAFVIDISGSMAGRKLEQTKEALLRILEDMQEEDYLNFILFSGD--VSTWKEHLVQATPE 342
Query: 230 TLQELKLWVKTLQPDGGSNLLQALKKIFTLKGLDSL 265
LQE + +VK+++ G +N+ L L+G+ L
Sbjct: 343 NLQEARTFVKSMEDKGMTNINDGL-----LRGISML 373
>gi|156119625 inter-alpha (globulin) inhibitor H1 [Homo sapiens]
Length = 911
Score = 42.7 bits (99), Expect = 0.002
Identities = 38/137 (27%), Positives = 64/137 (46%), Gaps = 18/137 (13%)
Query: 954 TVLESKVCILLDTSGSM-GPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTL 1012
T + V ++D SGSM G ++Q K L+ ++ + + D F+L+ F QSW+ +L
Sbjct: 287 TNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDM--QPGDYFDLVLFGTRVQSWKGSL 344
Query: 1013 VETTDAACHEAMQWVTHLQAQGSTSILQALLKAF--------SFHDLEG----LYLLTDG 1060
V+ ++A A +V +T++ LL+ S +L L +LTDG
Sbjct: 345 VQASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEILNQVQESLPELSNHASILIMLTDG 404
Query: 1061 KPD---TSCSLVLNEVQ 1074
P T S +L V+
Sbjct: 405 DPTEGVTDRSQILKNVR 421
Score = 41.6 bits (96), Expect = 0.005
Identities = 24/94 (25%), Positives = 44/94 (46%)
Query: 506 TVCEKRVVVLLDISATNSMYIIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVP 565
T K VV ++DIS + + L + + D F+L+ FG+ ++SW+ +V
Sbjct: 287 TNMNKNVVFVIDISGSMRGQKVKQTKEALLKILGDMQPGDYFDLVLFGTRVQSWKGSLVQ 346
Query: 566 VSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEV 599
S NLQ+A + + N+ L + +E+
Sbjct: 347 ASEANLQAAQDFVRGFSLDEATNLNGGLLRGIEI 380
Score = 32.0 bits (71), Expect = 3.6
Identities = 38/173 (21%), Positives = 77/173 (44%), Gaps = 18/173 (10%)
Query: 171 VSILIDVSAISSGPQKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSAST 230
V +ID+S G + ++ ++ L+ ++ + + + ++ FGT S ++ S +
Sbjct: 293 VVFVIDISGSMRGQKVKQTKEALLKILGD-MQPGDYFDLVLFGTRVQSWKGSLVQASEAN 351
Query: 231 LQELKLWVKTLQPDGGSNLLQALKKIFTLKGLDSLVAIMRSCPDQPSEILSDYIQQSTMG 290
LQ + +V+ D +NL L L+G++ L + S P+ LS++ M
Sbjct: 352 LQAAQDFVRGFSLDEATNLNGGL-----LRGIEILNQVQESLPE-----LSNHASILIML 401
Query: 291 RDLI-IHFITYRCDDQMPPAVLKNLAEAVRGYYHCYSPKMEHYTSRDMDELLA 342
D +T R +LKN+ A+RG + Y+ H + E+++
Sbjct: 402 TDGDPTEGVTDRSQ------ILKNVRNAIRGRFPLYNLGFGHNVDFNFLEVMS 448
>gi|194306644 BCSC-1 isoform 1 [Homo sapiens]
Length = 786
Score = 42.0 bits (97), Expect = 0.003
Identities = 44/172 (25%), Positives = 74/172 (43%), Gaps = 20/172 (11%)
Query: 963 LLDTSGSMGPYLQ---------QVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLV 1013
L+D SGSM + Q E ++L+ + L C FN+ F S+++ V
Sbjct: 285 LMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGC-YFNIYGFGSSYEACFPESV 343
Query: 1014 ETTDAACHEAMQWVTHLQAQ-GSTSILQALLKAFSFHDLEG----LYLLTDGKPDTSCSL 1068
+ T EA+ V +QA G T IL L + + G L++ TDG+ + S
Sbjct: 344 KYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFS- 402
Query: 1069 VLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGGRYHCPVGEDTL 1120
V+ EV+ R+K S + + ++ +A +GG G+D +
Sbjct: 403 VIKEVRINRQKH----RCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRM 450
>gi|38195080 BCSC-1 isoform 1 [Homo sapiens]
Length = 786
Score = 42.0 bits (97), Expect = 0.003
Identities = 44/172 (25%), Positives = 74/172 (43%), Gaps = 20/172 (11%)
Query: 963 LLDTSGSMGPYLQ---------QVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLV 1013
L+D SGSM + Q E ++L+ + L C FN+ F S+++ V
Sbjct: 285 LMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGC-YFNIYGFGSSYEACFPESV 343
Query: 1014 ETTDAACHEAMQWVTHLQAQ-GSTSILQALLKAFSFHDLEG----LYLLTDGKPDTSCSL 1068
+ T EA+ V +QA G T IL L + + G L++ TDG+ + S
Sbjct: 344 KYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFS- 402
Query: 1069 VLNEVQKLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGGRYHCPVGEDTL 1120
V+ EV+ R+K S + + ++ +A +GG G+D +
Sbjct: 403 VIKEVRINRQKH----RCFSFGIGEGTSTSLIKGIARASGGTSEFITGKDRM 450
>gi|110611231 chloride channel accessory 1 precursor [Homo sapiens]
Length = 914
Score = 39.7 bits (91), Expect = 0.017
Identities = 44/158 (27%), Positives = 72/158 (45%), Gaps = 18/158 (11%)
Query: 960 VCILLDTSGSM--GPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLVETTD 1017
VC++LD SGSM G L ++ L + + + S+ + +S Q+ L++
Sbjct: 307 VCLVLDKSGSMATGNRLNRLNQAGQLFLLQTVE--LGSWVGMVTFDSAAHVQNELIQINS 364
Query: 1018 AACHEAMQWVTHLQAQGSTSILQALLKAFSF------HDLEGLYLLTDGKPDTSCSLVLN 1071
+ + + A G TSI L AF+ D + LLTDG+ D + S N
Sbjct: 365 GSDRDTLAKRLPAAASGGTSICSGLRSAFTVIRKKYPTDGSEIVLLTDGE-DNTISGCFN 423
Query: 1072 EVQKLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGG 1109
EV ++ +HT++L S A + L +L+ TGG
Sbjct: 424 EV----KQSGAIIHTVALGPS---AAQELEELSKMTGG 454
>gi|239735575 otoancorin isoform 3 [Homo sapiens]
Length = 1060
Score = 38.5 bits (88), Expect = 0.038
Identities = 56/227 (24%), Positives = 93/227 (40%), Gaps = 15/227 (6%)
Query: 943 WLLSGSRRLFGTVLESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFA 1002
W L R + V +L G P L +K E + +W+ + +++S
Sbjct: 754 WALEDLRCMEEDTFIRTVELLGAVQGFSRPQLMTLK-EKAIQVWD-MPSYWREHHIVSLG 811
Query: 1003 ESFQSWQDTLVETTDAACHE---AMQWVTHLQAQGSTSILQALL--KAFSFHDLEGLYLL 1057
+ ++ +E D + + ++ W T + SILQ L +S DL+ +L+
Sbjct: 812 RIALALNESELEQLDLSSIDTVASLSWQTEWTPGQAESILQGYLDDSGYSIQDLKSFHLV 871
Query: 1058 TDGKPDTSCSLVLNEVQ--KLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGG--RYHC 1113
G T C++ + E+ K+ E R V +L CS EF RK G +
Sbjct: 872 --GLGATLCAINITEIPLIKISEFRVVVARIGTLLCSTHVLAEFKRKAEVVFGDPTEWTS 929
Query: 1114 PVGEDTLSKIHSLLTKGFINEKDPTLPP-FEGDDLRILAQEITKARS 1159
V ++ L I + LTK + D L P F+ ++ L EI K S
Sbjct: 930 SVLQE-LGTIAAGLTKAELRMLDKDLMPYFQPSAIKCLPDEIFKELS 975
>gi|24638452 otoancorin isoform 2 [Homo sapiens]
Length = 815
Score = 38.5 bits (88), Expect = 0.038
Identities = 56/227 (24%), Positives = 93/227 (40%), Gaps = 15/227 (6%)
Query: 943 WLLSGSRRLFGTVLESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFA 1002
W L R + V +L G P L +K E + +W+ + +++S
Sbjct: 509 WALEDLRCMEEDTFIRTVELLGAVQGFSRPQLMTLK-EKAIQVWD-MPSYWREHHIVSLG 566
Query: 1003 ESFQSWQDTLVETTDAACHE---AMQWVTHLQAQGSTSILQALL--KAFSFHDLEGLYLL 1057
+ ++ +E D + + ++ W T + SILQ L +S DL+ +L+
Sbjct: 567 RIALALNESELEQLDLSSIDTVASLSWQTEWTPGQAESILQGYLDDSGYSIQDLKSFHLV 626
Query: 1058 TDGKPDTSCSLVLNEVQ--KLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGG--RYHC 1113
G T C++ + E+ K+ E R V +L CS EF RK G +
Sbjct: 627 --GLGATLCAINITEIPLIKISEFRVVVARIGTLLCSTHVLAEFKRKAEVVFGDPTEWTS 684
Query: 1114 PVGEDTLSKIHSLLTKGFINEKDPTLPP-FEGDDLRILAQEITKARS 1159
V ++ L I + LTK + D L P F+ ++ L EI K S
Sbjct: 685 SVLQE-LGTIAAGLTKAELRMLDKDLMPYFQPSAIKCLPDEIFKELS 730
>gi|77404409 otoancorin isoform 1 [Homo sapiens]
Length = 1139
Score = 38.5 bits (88), Expect = 0.038
Identities = 56/227 (24%), Positives = 93/227 (40%), Gaps = 15/227 (6%)
Query: 943 WLLSGSRRLFGTVLESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFA 1002
W L R + V +L G P L +K E + +W+ + +++S
Sbjct: 833 WALEDLRCMEEDTFIRTVELLGAVQGFSRPQLMTLK-EKAIQVWD-MPSYWREHHIVSLG 890
Query: 1003 ESFQSWQDTLVETTDAACHE---AMQWVTHLQAQGSTSILQALL--KAFSFHDLEGLYLL 1057
+ ++ +E D + + ++ W T + SILQ L +S DL+ +L+
Sbjct: 891 RIALALNESELEQLDLSSIDTVASLSWQTEWTPGQAESILQGYLDDSGYSIQDLKSFHLV 950
Query: 1058 TDGKPDTSCSLVLNEVQ--KLREKRDVKVHTISLNCSDRAAVEFLRKLASFTGG--RYHC 1113
G T C++ + E+ K+ E R V +L CS EF RK G +
Sbjct: 951 --GLGATLCAINITEIPLIKISEFRVVVARIGTLLCSTHVLAEFKRKAEVVFGDPTEWTS 1008
Query: 1114 PVGEDTLSKIHSLLTKGFINEKDPTLPP-FEGDDLRILAQEITKARS 1159
V ++ L I + LTK + D L P F+ ++ L EI K S
Sbjct: 1009 SVLQE-LGTIAAGLTKAELRMLDKDLMPYFQPSAIKCLPDEIFKELS 1054
>gi|38195082 BCSC-1 isoform 2 [Homo sapiens]
Length = 415
Score = 37.4 bits (85), Expect = 0.085
Identities = 38/131 (29%), Positives = 60/131 (45%), Gaps = 16/131 (12%)
Query: 963 LLDTSGSMGPYLQ---------QVKTELVLLIWEQLRKCCDSFNLLSFAESFQSWQDTLV 1013
L+D SGSM + Q E ++L+ + L C FN+ F S+++ V
Sbjct: 285 LMDRSGSMQSPMSSQDTSQLRIQAAKETLILLLKSLPIGC-YFNIYGFGSSYEACFPESV 343
Query: 1014 ETTDAACHEAMQWVTHLQAQ-GSTSILQALLKAFSFHDLEG----LYLLTDGKPDTSCSL 1068
+ T EA+ V +QA G T IL L + + G L++ TDG+ + S
Sbjct: 344 KYTQQTMEEALGRVKLMQADLGGTEILAPLQNIYRGPSIPGHPLQLFVFTDGEVTDTFS- 402
Query: 1069 VLNEVQKLREK 1079
V+ EV+ R+K
Sbjct: 403 VIKEVRINRQK 413
>gi|224831239 integrin alpha M isoform 1 precursor [Homo sapiens]
Length = 1153
Score = 34.7 bits (78), Expect = 0.55
Identities = 17/50 (34%), Positives = 30/50 (60%)
Query: 957 ESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQ 1006
+S + L+D SGS+ P+ + E V + EQL+K F+L+ ++E F+
Sbjct: 148 DSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTLFSLMQYSEEFR 197
>gi|88501734 integrin alpha M isoform 2 precursor [Homo sapiens]
Length = 1152
Score = 34.7 bits (78), Expect = 0.55
Identities = 17/50 (34%), Positives = 30/50 (60%)
Query: 957 ESKVCILLDTSGSMGPYLQQVKTELVLLIWEQLRKCCDSFNLLSFAESFQ 1006
+S + L+D SGS+ P+ + E V + EQL+K F+L+ ++E F+
Sbjct: 148 DSDIAFLIDGSGSIIPHDFRRMKEFVSTVMEQLKKSKTLFSLMQYSEEFR 197
>gi|161169015 neuron navigator 2 isoform 3 [Homo sapiens]
Length = 2365
Score = 33.9 bits (76), Expect = 0.94
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 6/119 (5%)
Query: 735 PKEKPKTLQLRSQPKKLCPPRPTVPLGARM-SIKDDPDREKSPPLKSLKWRPLSSRVGIS 793
PKE P + PKK +P G ++ S K +P +P + + S G S
Sbjct: 456 PKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEP---MAPSHSGIPKPGMKSMPGKS 512
Query: 794 PAAAQPTKEGMMELRRKTKS--REAETSLLLFYTEKGNDVGSVYKKYPQGRGLRRTSSS 850
P+A P+KEG K S + + L ++ + + S K P G L + SS
Sbjct: 513 PSAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISS 571
>gi|161169013 neuron navigator 2 isoform 1 [Homo sapiens]
Length = 2432
Score = 33.9 bits (76), Expect = 0.94
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 6/119 (5%)
Query: 735 PKEKPKTLQLRSQPKKLCPPRPTVPLGARM-SIKDDPDREKSPPLKSLKWRPLSSRVGIS 793
PKE P + PKK +P G ++ S K +P +P + + S G S
Sbjct: 520 PKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEP---MAPSHSGIPKPGMKSMPGKS 576
Query: 794 PAAAQPTKEGMMELRRKTKS--REAETSLLLFYTEKGNDVGSVYKKYPQGRGLRRTSSS 850
P+A P+KEG K S + + L ++ + + S K P G L + SS
Sbjct: 577 PSAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISS 635
>gi|38044282 neuron navigator 2 isoform 2 [Homo sapiens]
Length = 2429
Score = 33.9 bits (76), Expect = 0.94
Identities = 32/119 (26%), Positives = 49/119 (41%), Gaps = 6/119 (5%)
Query: 735 PKEKPKTLQLRSQPKKLCPPRPTVPLGARM-SIKDDPDREKSPPLKSLKWRPLSSRVGIS 793
PKE P + PKK +P G ++ S K +P +P + + S G S
Sbjct: 520 PKEDPSGAAVPEMPKKSSKIASFIPKGGKLNSAKKEP---MAPSHSGIPKPGMKSMPGKS 576
Query: 794 PAAAQPTKEGMMELRRKTKS--REAETSLLLFYTEKGNDVGSVYKKYPQGRGLRRTSSS 850
P+A P+KEG K S + + L ++ + + S K P G L + SS
Sbjct: 577 PSAPAPSKEGERSRSGKLSSGLPQQKPQLDGRHSSSSSSLASSEGKGPGGTTLNHSISS 635
>gi|45504376 synaptotagmin VI [Homo sapiens]
Length = 425
Score = 33.5 bits (75), Expect = 1.2
Identities = 45/170 (26%), Positives = 68/170 (40%), Gaps = 22/170 (12%)
Query: 730 GSSALPKEKPKTLQLRSQPKKLCPPRPTVPLGARMSIKDD------PDREKSPPLKSLKW 783
G+ A + P TL K+ P +P +MS+K+ R+ + P S +
Sbjct: 28 GNMADKLKDPSTLGFLEAAVKISHTSPDIPAEVQMSVKEHIMRHTRLQRQTTEPASSTRH 87
Query: 784 ----RPLSSRVGIS---------PAAAQPTKEGMMELR-RKTKSREAETSLLLFYTEKGN 829
R L ++ +S PAA QPT G ++ K KS + E + G
Sbjct: 88 TSFKRHLPRQMHVSSVDYGNELPPAAEQPTSIGRIKPELYKQKSVDGEDAKSEATKSCGK 147
Query: 830 DVGSVYKKYPQGRGLRRTSSSIDLPRKDTVCSSQEWVAKYGL--KKLKLE 877
S+ Y + R + DLP KD SS +V Y L +K KL+
Sbjct: 148 INFSLRYDYETETLIVRILKAFDLPAKDFCGSSDPYVKIYLLPDRKCKLQ 197
>gi|157412247 RUN and SH3 domain containing 1 isoform b [Homo
sapiens]
Length = 796
Score = 33.1 bits (74), Expect = 1.6
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 9/81 (11%)
Query: 725 SGKVLGSSALPKEKPKTLQLRSQPKKLCPPRP--TVPLGARMSIKDDPDREKSPPLKSLK 782
SG GSSA P+E +LRS+ + PP P P+G + P R PP+
Sbjct: 355 SGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALV----PPRPPPPPVPP-- 408
Query: 783 WRPLSSRVGISPAAAQPTKEG 803
R +R G+ P A ++EG
Sbjct: 409 -RRKKNRPGLQPIAEGQSEEG 428
>gi|157412245 RUN and SH3 domain containing 1 isoform a [Homo
sapiens]
Length = 902
Score = 33.1 bits (74), Expect = 1.6
Identities = 27/81 (33%), Positives = 38/81 (46%), Gaps = 9/81 (11%)
Query: 725 SGKVLGSSALPKEKPKTLQLRSQPKKLCPPRP--TVPLGARMSIKDDPDREKSPPLKSLK 782
SG GSSA P+E +LRS+ + PP P P+G + P R PP+
Sbjct: 355 SGSPGGSSAPPREVTTFKELRSRSRAPAPPVPPRDPPVGWALV----PPRPPPPPVPP-- 408
Query: 783 WRPLSSRVGISPAAAQPTKEG 803
R +R G+ P A ++EG
Sbjct: 409 -RRKKNRPGLQPIAEGQSEEG 428
>gi|116517292 cut-like 2 [Homo sapiens]
Length = 1486
Score = 33.1 bits (74), Expect = 1.6
Identities = 39/171 (22%), Positives = 72/171 (42%), Gaps = 31/171 (18%)
Query: 736 KEKPKTLQLRSQPKKLCPPRPTVPLGARM-----------SIKDDPDREKSPPLKSLKWR 784
K P+ L + Q + P PT+ G+R+ ++ + EK L+ ++
Sbjct: 136 KRNPELLSPKEQREGTSPAGPTLTEGSRLPGIPGKALLTETLLQRNEAEKQKGLQEVQ-I 194
Query: 785 PLSSRVG-------ISPAAAQPTKEGMMELRRK----TKSREAETSLLLFYTEKGNDVGS 833
L++R+G + +A + T+ ++ELRRK S+ E L++ EK N
Sbjct: 195 TLAARLGEAEEKIKVLHSALKATQAELLELRRKYDEEAASKADEVGLIMTNLEKANQRAE 254
Query: 834 VYKKYPQGRGLRRTSSSIDLPRKDTVCSSQEWVAKYGLKKLKLEISRCMGP 884
++ + LR +S++ + CS Q G K+ + C GP
Sbjct: 255 AAQR--EVESLREQLASVNSSIRLACCSPQ------GPSGDKVNFTLCSGP 297
>gi|210147462 von Willebrand factor A domain containing 5B1 [Homo
sapiens]
Length = 1215
Score = 32.3 bits (72), Expect = 2.7
Identities = 24/83 (28%), Positives = 39/83 (46%), Gaps = 1/83 (1%)
Query: 513 VVLLDISATNSMYIIHIQHSLRLLLEEQLSNKDCFNLIAFGSTIESWRPEMVPVSHNNLQ 572
+ L+D S++ S +H L+ + L FN+I FGST +S P S ++L
Sbjct: 363 IFLIDRSSSMSGISMHRVKDAMLVALKSLMPACLFNIIGFGSTFKSLFPSSQTYSEDSLA 422
Query: 573 SAWRWALNLRC-RGSRNVLSALR 594
A ++ G N+LS L+
Sbjct: 423 MACDDIQRMKADMGGTNILSPLK 445
>gi|81295809 pericentrin [Homo sapiens]
Length = 3336
Score = 32.0 bits (71), Expect = 3.6
Identities = 44/186 (23%), Positives = 72/186 (38%), Gaps = 39/186 (20%)
Query: 185 QKEEFQKDLMSLIDEQLSHKEKLFVLSFGTNAGSLWPDPMEVSASTLQELKLW------V 238
+KE K + +L+ ++ LS G S P P +Q++ L V
Sbjct: 2384 EKEVRPKHVKALLQMVRDESHQILALSEGLAPPSGEPHPPR-KEDEIQDISLHGGKTQEV 2442
Query: 239 KTLQPDGGSNLLQALKKIFTLKGLDSLVAIMRSCPDQPSEILSDYIQQSTMGRDLIIHFI 298
T PD +LLQ +++ F ++ E+ +Q G DL H
Sbjct: 2443 PTACPDWRGDLLQVVQEAF----------------EKEQEMQGVELQPRLSGSDLGGH-- 2484
Query: 299 TYRCDDQMPPAVLKNLAEAVRGYYHCYSPKMEHYTSRDMDELLAEIQ--KAQSLLSHVQ- 355
++L+ L + +R +EH D LL+EIQ +AQ ++H+Q
Sbjct: 2485 ---------SSLLERLEKIIREQGDLQEKSLEHLRLPDRSSLLSEIQALRAQLRMTHLQN 2535
Query: 356 --ALQH 359
LQH
Sbjct: 2536 QEKLQH 2541
>gi|4506431 RAS p21 protein activator 1 isoform 1 [Homo sapiens]
Length = 1047
Score = 31.6 bits (70), Expect = 4.7
Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 566 VSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQDMP 625
+ HN L+ W W NLR ++ L VE +++D H +G F G I Q+
Sbjct: 308 IVHNELEDGWMWVTNLRTDEQGLIVEDL---VEEVGREEDPH--EGKIWFHGKISKQEAY 362
Query: 626 TLSAYMAEAC 635
L + + C
Sbjct: 363 NLLMTVGQVC 372
>gi|12545406 RAS p21 protein activator 1 isoform 2 [Homo sapiens]
Length = 870
Score = 31.6 bits (70), Expect = 4.7
Identities = 20/70 (28%), Positives = 31/70 (44%), Gaps = 5/70 (7%)
Query: 566 VSHNNLQSAWRWALNLRCRGSRNVLSALRKAVEVDFKDKDKHQSQGIYLFTGGIPDQDMP 625
+ HN L+ W W NLR ++ L VE +++D H +G F G I Q+
Sbjct: 131 IVHNELEDGWMWVTNLRTDEQGLIVEDL---VEEVGREEDPH--EGKIWFHGKISKQEAY 185
Query: 626 TLSAYMAEAC 635
L + + C
Sbjct: 186 NLLMTVGQVC 195
Database: hs.faa
Posted date: Aug 4, 2009 4:42 PM
Number of letters in database: 18,247,518
Number of sequences in database: 37,866
Lambda K H
0.318 0.132 0.394
Gapped
Lambda K H
0.267 0.0410 0.140
Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 45,586,912
Number of Sequences: 37866
Number of extensions: 2038300
Number of successful extensions: 5808
Number of sequences better than 10.0: 30
Number of HSP's better than 10.0 without gapping: 13
Number of HSP's successfully gapped in prelim test: 22
Number of HSP's that attempted gapping in prelim test: 5724
Number of HSP's gapped (non-prelim): 77
length of query: 1184
length of database: 18,247,518
effective HSP length: 113
effective length of query: 1071
effective length of database: 13,968,660
effective search space: 14960434860
effective search space used: 14960434860
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 68 (30.8 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.
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Guide to the Human Genome
Copyright © 2010 by Stewart Scherer. All rights reserved.