Search of human proteins with 21735621

Search of human proteins with 21735621

BLASTP 2.2.11 [Jun-05-2005]


Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, 
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997), 
"Gapped BLAST and PSI-BLAST: a new generation of protein database search
programs",  Nucleic Acids Res. 25:3389-3402.

Query= gi|21735621 mitochondrial malate dehydrogenase precursor [Homo
sapiens]
         (338 letters)

Database: hs.faa 
           37,866 sequences; 18,247,518 total letters

Searching..................................................done

                                                                 Score    E
Sequences producing significant alignments:                      (bits) Value

gi|21735621 mitochondrial malate dehydrogenase precursor [Homo s...   663   0.0  
gi|4557032 L-lactate dehydrogenase B [Homo sapiens]                    57   2e-08
gi|239755954 PREDICTED: hypothetical protein [Homo sapiens]            32   1.1  
gi|239750480 PREDICTED: hypothetical protein [Homo sapiens]            32   1.1  
gi|222418558 methylenetetrahydrofolate dehydrogenase 2-like [Hom...    30   2.4  
gi|29029557 Bardet-Biedl syndrome 7 protein isoform a [Homo sapi...    29   6.8  
gi|29029555 Bardet-Biedl syndrome 7 protein isoform b [Homo sapi...    29   6.8  
gi|31543198 serine/threonine kinase 40 [Homo sapiens]                  28   8.9  

>gi|21735621 mitochondrial malate dehydrogenase precursor [Homo
           sapiens]
          Length = 338

 Score =  663 bits (1710), Expect = 0.0
 Identities = 338/338 (100%), Positives = 338/338 (100%)

Query: 1   MLSALARPASAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH 60
           MLSALARPASAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH
Sbjct: 1   MLSALARPASAALRRSFSTSAQNNAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAH 60

Query: 61  TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATI 120
           TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATI
Sbjct: 61  TPGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATI 120

Query: 121 VATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTF 180
           VATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTF
Sbjct: 121 VATLTAACAQHCPEAMICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTF 180

Query: 181 VAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKA 240
           VAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKA
Sbjct: 181 VAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQDQLTALTGRIQEAGTEVVKA 240

Query: 241 KAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIE 300
           KAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIE
Sbjct: 241 KAGAGSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQETECTYFSTPLLLGKKGIE 300

Query: 301 KNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK 338
           KNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK
Sbjct: 301 KNLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK 338


>gi|4557032 L-lactate dehydrogenase B [Homo sapiens]
          Length = 334

 Score = 57.4 bits (137), Expect = 2e-08
 Identities = 75/337 (22%), Positives = 136/337 (40%), Gaps = 47/337 (13%)

Query: 24  NAKVAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHTP--GVAADLSH----IETKAAV 77
           N K+ V+G  G +G   ++ +    L   L L D+      G   DL H    ++T   V
Sbjct: 21  NNKITVVGV-GQVGMACAISILGKSLADELALVDVLEDKLKGEMMDLQHGSLFLQTPKIV 79

Query: 78  --KGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIVATLTAACAQHCPEA 135
             K Y              +VV+ AGV ++ G +R +L   N  +   +     ++ P+ 
Sbjct: 80  ADKDY-------SVTANSKIVVVTAGVRQQEGESRLNLVQRNVNVFKFIIPQIVKYSPDC 132

Query: 136 MICVIANPVNSTIPITAEVFKKHGVYNPNKIFGVTTLDIVRANTFVAELKGLDPARVNVP 195
           +I V++NPV+    +T   +K  G+     I     LD  R    +AE  G+ P+  +  
Sbjct: 133 IIIVVSNPVDI---LTYVTWKLSGLPKHRVIGSGCNLDSARFRYLMAEKLGIHPSSCHGW 189

Query: 196 VIGGHAGKTII---------PLISQCTPKV--DFPQDQLTALTGRIQEAGTEVVKAKAGA 244
           ++G H   ++            + +  P++  D   +    +   + E+  EV+K K   
Sbjct: 190 ILGEHGDSSVAVWSGVNVAGVSLQELNPEMGTDNDSENWKEVHKMVVESAYEVIKLK--- 246

Query: 245 GSATLSMAYAGARFVFSLVDAMNGKEGVVECSFVKSQ---ETECTYFSTPLLLGKKGIEK 301
           G    ++  + A  + S++  ++    V   + VK     E E  + S P +L  +G+  
Sbjct: 247 GYTNWAIGLSVADLIESMLKNLSRIHPV--STMVKGMYGIENE-VFLSLPCILNARGL-- 301

Query: 302 NLGIGKVSSFEEKMISDAIPELKASIKKGEDFVKTLK 338
                  S   +K+  D + +LK S     D  K LK
Sbjct: 302 ------TSVINQKLKDDEVAQLKKSADTLWDIQKDLK 332


>gi|239755954 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 274

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 21/57 (36%), Positives = 27/57 (47%)

Query: 31  GASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPEQLP 87
           G+S G GQ L L    + L  RL  + +   P V+A LS   T+A V     P Q P
Sbjct: 203 GSSAGAGQSLVLHRLPTRLQKRLAHWPLGRPPAVSASLSTPSTEATVTRSPHPPQNP 259


>gi|239750480 PREDICTED: hypothetical protein [Homo sapiens]
          Length = 274

 Score = 31.6 bits (70), Expect = 1.1
 Identities = 21/57 (36%), Positives = 27/57 (47%)

Query: 31  GASGGIGQPLSLLLKNSPLVSRLTLYDIAHTPGVAADLSHIETKAAVKGYLGPEQLP 87
           G+S G GQ L L    + L  RL  + +   P V+A LS   T+A V     P Q P
Sbjct: 203 GSSAGAGQSLVLHRLPTRLQKRLAHWPLGRPPAVSASLSTPSTEATVTRSPHPPQNP 259


>gi|222418558 methylenetetrahydrofolate dehydrogenase 2-like [Homo
           sapiens]
          Length = 347

 Score = 30.4 bits (67), Expect = 2.4
 Identities = 29/120 (24%), Positives = 45/120 (37%), Gaps = 19/120 (15%)

Query: 3   SALARPASAALRRSFSTSAQNNAK-VAVLGASGGIGQPLSLLLKNSPLVSRLTLYDIAHT 61
           S +   ASA       T  Q   K V V G S  +G P+++LL               HT
Sbjct: 185 SLIPATASAVWEIIKRTGIQTFGKNVVVAGRSKNVGMPIAMLL---------------HT 229

Query: 62  PGVAADLSHIETKAAVKGYLGPEQLPDCLKGCDVVVIPAGVPRKPGMTRDDLFNTNATIV 121
            G         T      Y   EQL    +  D++++ AG+P+   +   D+    A ++
Sbjct: 230 DGEHERPGGDATVTIAHRYTPKEQLKIHTQLADIIIVAAGIPK---LITSDMVKEGAAVI 286


>gi|29029557 Bardet-Biedl syndrome 7 protein isoform a [Homo
           sapiens]
          Length = 715

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 4/65 (6%)

Query: 270 EGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKK 329
           +GVV C  +K  E    + + P   G K     LG G +++ +EK+   A  E++   K+
Sbjct: 41  DGVVMCFGMKKGEAAAVFKTLP---GPKIARLELG-GVINTPQEKIFIAAASEIRGFTKR 96

Query: 330 GEDFV 334
           G+ F+
Sbjct: 97  GKQFL 101


>gi|29029555 Bardet-Biedl syndrome 7 protein isoform b [Homo
           sapiens]
          Length = 672

 Score = 28.9 bits (63), Expect = 6.8
 Identities = 19/65 (29%), Positives = 33/65 (50%), Gaps = 4/65 (6%)

Query: 270 EGVVECSFVKSQETECTYFSTPLLLGKKGIEKNLGIGKVSSFEEKMISDAIPELKASIKK 329
           +GVV C  +K  E    + + P   G K     LG G +++ +EK+   A  E++   K+
Sbjct: 41  DGVVMCFGMKKGEAAAVFKTLP---GPKIARLELG-GVINTPQEKIFIAAASEIRGFTKR 96

Query: 330 GEDFV 334
           G+ F+
Sbjct: 97  GKQFL 101


>gi|31543198 serine/threonine kinase 40 [Homo sapiens]
          Length = 435

 Score = 28.5 bits (62), Expect = 8.9
 Identities = 26/101 (25%), Positives = 46/101 (45%), Gaps = 12/101 (11%)

Query: 176 RANTFVAELKGLDPARVNVPVIGGHAGKTIIPLISQCTPKVDFPQD--QLTALTGRIQEA 233
           RA    + + G +  R    ++G   G + +P I QC  + D   D  QL  LT  ++E 
Sbjct: 16  RAKALGSGISGNNAKRAGPFILGPRLGNSPVPSIVQCLARKDGTDDFYQLKILT--LEER 73

Query: 234 GTEVVKA-KAGAGSATLSMAYAGARFVFSLVDAMNGKEGVV 273
           G + +++ +   G   L   Y       SL+  ++ ++GVV
Sbjct: 74  GDQGIESQEERQGKMLLHTEY-------SLLSLLHTQDGVV 107


  Database: hs.faa
    Posted date:  Aug 4, 2009  4:42 PM
  Number of letters in database: 18,247,518
  Number of sequences in database:  37,866
  
Lambda     K      H
   0.317    0.133    0.380 

Gapped
Lambda     K      H
   0.267   0.0410    0.140 


Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Number of Hits to DB: 11,932,134
Number of Sequences: 37866
Number of extensions: 506693
Number of successful extensions: 1153
Number of sequences better than 10.0: 8
Number of HSP's better than 10.0 without gapping: 4
Number of HSP's successfully gapped in prelim test: 4
Number of HSP's that attempted gapping in prelim test: 1149
Number of HSP's gapped (non-prelim): 8
length of query: 338
length of database: 18,247,518
effective HSP length: 103
effective length of query: 235
effective length of database: 14,347,320
effective search space: 3371620200
effective search space used: 3371620200
T: 11
A: 40
X1: 16 ( 7.3 bits)
X2: 38 (14.6 bits)
X3: 64 (24.7 bits)
S1: 41 (21.7 bits)
S2: 62 (28.5 bits)
Search results were obtained with NCBI BLAST and RefSeq entries.